synovitis: ['Inflammation of the SYNOVIAL MEMBRANE [ MeSH ]']
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
328 |
4. Check minimum number of eventsNone |
328 |
5. Include endpointsNone |
328 |
6. Filter based on genotype QC (FinnGen only) |
328 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M67
- Name in latin
- Synovitis transitoria
Similar endpoints
↥List of similar endpoints to Transient synovitis based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 4739 | 1722 | 3013 |
Only index persons | 3886 | 1464 | 2422 |
Unadjusted period prevalence (%) | |||
Whole population | 0.07 | 0.05 | 0.08 |
Only index persons | 0.08 | 0.05 | 0.09 |
Median age at first event (years) | |||
Whole population | 6.89 | 8.17 | 6.11 |
Only index persons | 8.02 | 10.50 | 6.51 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 328 | 191 | 137 |
Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.06 |
Median age at first event (years) | 23.78 | 30.04 | 15.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 286
- Matched controls
- 2859
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint M13_TRANSSYNOVITIS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_TRANSSYNOVITIS | 1.188 [0.89, 1.59] | 0.244 |
Birth year | 0.993 [0.98, 1.0] | 0.098 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 1551 females with M13_TRANSSYNOVITIS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_TRANSSYNOVITIS | 1.195 [0.91, 1.56] | 0.196 |
Birth year | 0.989 [0.98, 1.0] | 0.024 |
During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 2694 males with M13_TRANSSYNOVITIS died.
Mortality risk
Mortality risk for people of age
years, who have M13_TRANSSYNOVITIS.N-year risk | Females | Males |
---|---|---|
1 | 0.096% | 0.247% |
5 | 0.579% | 1.482% |
10 | 1.456% | 3.667% |
15 | 2.989% | 7.022% |
20 | 5.127% | 11.837% |
Relationships between endpoints
↥Index endpoint: M13_TRANSSYNOVITIS – Transient synovitis
GWS hits: 1