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Isolated proteinuria with specified morphological lesion

DOID EFO Endpoint Browser PheWeb

N14_ISOLPROTEINURIA

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N06#
  • Cause of death: ICD-10 — N06#

2 out of 7 registries used, show all original rules.

415

4. Check minimum number of events

None

415

5. Include endpoints

None

415

6. Filter based on genotype QC (FinnGen only)

394

Control definitions (FinnGen only)

Control exclude
N14_GLOMERULAR

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N00-N08
Name in latin
Proteinuria isolata cum laesione morphologica specificata

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2409 1167 1221
Only index persons 2118 1030 1088
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.04 0.04 0.04
Median age at first event (years)
Whole population 57.83 56.49 59.16
Only index persons 55.61 53.58 57.53

-FinnGen-

Key figures

All Female Male
Number of individuals 394 196 198
Unadjusted period prevalence (%) 0.08 0.07 0.09
Median age at first event (years) 56.76 51.94 61.53

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
415
Matched controls
4150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N06.9
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, unspecified
+∞
258.2
220
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
107.2
177.6
92
11
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
73.6
167.8
92
16
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
87.5
157.8
84
12
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
19.3
146.7
130
96
N18.8
ICD-10 Finland
Other chronic renal failure
47.0
133.0
80
21
A11CC03
ATC
alfacalcidol; systemic
37.6
120.5
77
25
A12AA04
ATC
calcium carbonate; oral
64.8
109.4
61
11
L04AA06
ATC
mycophenolic acid; systemic
37.0
98.8
63
20
127
Kela drug reimbursment
Transplant complication
48.6
93.0
55
13
TK800
NOMESCO Finland
Hemodialysis
34.6
87.9
57
19
N06.0
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, minor glomerular abnormality
+∞
84.3
78
*
B03XA02
ATC
darbepoetin alfa; parenteral
30.7
83.0
56
21
Z49.1
ICD-10 Finland
Extracorporeal dialysis
51.6
78.9
46
10
R80
ICD-10 Finland
Isolated proteinuria
154.5
73.7
76
6
L04AD01
ATC
ciclosporin; systemic
24.0
63.9
47
22
C03CA01
ATC
furosemide; systemic
5.1
60.2
228
803
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
121.1
58.6
62
6
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
8.8
54.9
76
103
Z94.0
ICD-10 Finland
Kidney transplant status
206.3
53.3
54
*
205
Kela drug reimbursment
Chronic hypertension
4.6
51.0
193
663
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
48.9
46
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
184.6
48.0
49
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.1
46.2
121
308
KA1AE
NOMESCO Finland
Kidney ultrasound examination
13.6
45.1
44
36
N06.1
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, focal and segmental glomerular lesions
+∞
44.6
42
*
C08CA01
ATC
amlodipine; oral
4.0
43.4
245
1090
Z49.0
ICD-10 Finland
Preparatory care for dialysis
100.7
41.7
45
5
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
122.7
41.6
44
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
73.6
41.0
46
7
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
226.8
40.6
41
*
C09AA02
ATC
enalapril; systemic
4.1
39.5
147
485
N18.0
ICD-10 Finland
End-stage renal disease
208.5
37.4
38
*
L04AD02
ATC
tacrolimus; systemic
110.4
37.4
40
*
137
Kela drug reimbursment
Uraemia requiring dialysis
143.1
37.4
39
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
37.0
35
*
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
+∞
37.0
35
*
M04AA01
ATC
allopurinol; systemic
4.5
36.4
110
309
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
+∞
36.0
34
*
B05DB
ATC
Hypertonic solutions
365.6
34.5
34
*
B05DA
ATC
Isotonic solutions
190.6
34.3
35
*
L04AA01
ATC
[U] ciclosporin
42.2
34.1
42
11
V03AE01
ATC
polystyrene sulfonate; oral
69.5
33.6
38
6
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.3
33.4
61
110
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
127.1
33.2
35
*
WW200
NOMESCO Finland
Immunization
12.3
33.1
34
30
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.5
32.0
93
252
N06.8
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, other
+∞
31.7
30
*
N19
ICD-10 Finland
Unspecified kidney failure
8.1
31.1
44
60
Z49.2
ICD-10 Finland
Other dialysis
172.9
31.1
32
*
H02AB04
ATC
methylprednisolone; systemic
4.0
30.6
108
337
N17.9
ICD-10 Finland
Acute renal failure, unspecified
8.2
30.3
42
56
C08CA02
ATC
felodipine; oral
4.7
29.8
78
194
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.2
29.3
194
897
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
161.2
29.0
30
*
L01BA01
ATC
methotrexate; systemic
8.6
28.6
38
48
N06.2
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse membranous glomerulonephritis
+∞
28.5
27
*
N04.0
ICD-10 Finland
Nephrotic syndrome, minor glomerular abnormality
+∞
28.5
27
*
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
83.7
28.2
31
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
8.8
26.9
35
43
C02AC05
ATC
moxonidine; oral
6.2
26.8
49
88
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
276.9
26.0
26
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.2
24.4
54
116
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
24.2
23
*
P01BA02
ATC
hydroxychloroquine; oral
4.5
24.1
66
169
M10.9
ICD-10 Finland
Gout, unspecified
4.9
24.0
57
130
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
254.1
23.9
24
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
7.6
23.2
34
48
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
+∞
23.1
22
*
C10AA05
ATC
atorvastatin; oral
2.8
22.7
221
1215
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
84.8
21.9
24
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
121.5
21.8
23
*
N04.2
ICD-10 Finland
Nephrotic syndrome, diffuse membranous glomerulonephritis
+∞
21.0
20
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
4.9
20.9
49
110
V03AE02
ATC
sevelamer; oral
220.6
20.8
21
*
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
20.0
19
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.5
19.7
29
41
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
19.7
234
1388
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
6.7
19.6
32
51
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.4
19.4
40
80
ZX120
NOMESCO Finland
Intravenous
3.7
19.3
69
213
L04AX01
ATC
azathioprine; systemic
6.2
19.2
34
59
I10
ICD-10 Finland
Essential (primary) hypertension
2.7
19.1
291
1931
N06.3
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse mesangial proliferative glomerulonephritis
+∞
18.9
18
*
N03.0
ICD-10 Finland
Chronic nephritic syndrome, minor glomerular abnormality
+∞
18.9
18
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
18.9
18
*
N03.2
ICD-10 Finland
Chronic nephritic syndrome, diffuse membranous glomerulonephritis
+∞
18.9
18
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
104.8
18.7
20
*
C09CA01
ATC
losartan; oral
2.6
18.4
146
710
C08CA13
ATC
lercanidipine; oral
3.1
18.2
92
352
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.1
17.9
39
82
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
17.8
17
*
TK820
NOMESCO Finland
Peritoneal dialysis
99.4
17.7
19
*
V03AE03
ATC
lanthanum carbonate; oral
187.7
17.7
18
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.1
17.3
51
137
H05BX01
ATC
cinacalcet; oral
36.7
16.8
21
6
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
36.7
16.8
21
6
C10AA01
ATC
simvastatin; oral
2.3
16.0
205
1221
3025
Kela drug reimbursment
Calcium carbonate
62.5
15.9
18
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
15.7
138
695
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
88.5
15.7
17
*
B03XA01
ATC
erythropoietin; parenteral
21.0
15.3
22
11
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.9
15.2
35
77
E66.00
ICD-10 Finland
Metabolic syndrome
4.4
15.1
40
99
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
33.1
14.9
19
6
321
Kela drug reimbursment
Paricalcitol and cinacalcet
33.1
14.9
19
6
H02AB06
ATC
prednisolone; systemic
2.3
14.8
229
1462
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
14.7
14
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
14.5
63
219
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.9
14.4
45
126
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
20.0
14.4
21
11
L04AA13
ATC
[U] leflunomide
10.6
13.7
26
26
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.8
13.6
44
126
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.3
13.5
145
790
RD210, ,
NOMESCO Finland
12.1
13.5
24
21
KBV00
NOMESCO Finland
Insertion of stent into ureter
41.5
13.2
16
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
6.2
13.2
23
39
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
12.9
58
205
R50.9
ICD-10 Finland
Fever, unspecified
2.7
12.8
82
352
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
12.6
125
656
N03.5
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
12.6
12
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
133.9
12.5
13
*
J01MA14
ATC
moxifloxacin; systemic
3.0
12.4
58
210
K65.0
ICD-10 Finland
Acute peritonitis
14.9
12.4
20
14
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
12.3
64
246
C07AG02
ATC
carvedilol; oral
3.6
12.3
42
125
A07EC01
ATC
sulfasalazine; oral, rectal
3.3
12.1
49
163
E66.8
ICD-10 Finland
Other obesity
4.2
12.0
33
84
B01AA03
ATC
warfarin; systemic
2.4
11.8
95
454
M01CB01
ATC
sodium aurothiomalate; parenteral
13.1
11.7
20
16
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.7
11.7
72
302
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.9
11.6
21
37
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
11.5
11
*
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
+∞
11.5
11
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.8
11.3
60
233
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
11.3
108
555
WX202
NOMESCO Finland
Supraclavicular plexus blockade
11.6
11.2
20
18
R4190
NOMESCO Finland
Nutritional therapy
4.6
11.1
27
62
Z3231
NOMESCO Finland
Registered nurse
2.1
11.0
134
759
L04AX03
ATC
methotrexate; systemic
2.9
10.8
56
214
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
13.4
10.7
18
14
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
10.7
91
443
A46
ICD-10 Finland
Erysipelas
2.5
10.7
79
362
C07AB07
ATC
bisoprolol; oral
2.0
10.6
222
1522
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
10.5
10
*
7910X
ICD-9 Finland
Nonspecific findings on examination of urine, Proteinuria[PROTEINURIA NUD]
+∞
10.5
10
*
N06.4
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse endocapillary proliferative glomerulonephritis
+∞
10.5
10
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
10.5
10
*
58209
ICD-8 Finland
Chronic nephritis, Unspecified
+∞
10.5
10
*
N06.5
ICD-10 Finland
Isolated proteinuria with specified morphological lesion, diffuse mesangiocapillary glomerulonephritis
+∞
10.5
10
*
M13.9
ICD-10 Finland
Arthritis, unspecified
3.1
10.4
45
155
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.4
10.1
38
120
N02AX02
ATC
tramadol; systemic, rectal
1.9
9.9
195
1299
U14
ICPC
Kidney symptom/complaint
11.0
9.9
18
17
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
9.9
83
402
L88
ICPC
Rheumatoid/seropositive arthritis
4.3
9.8
26
64
C07FB02
ATC
metoprolol and felodipine; systemic
5.0
9.6
21
44
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
9.6
115
642
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.6
9.5
59
248
TQW80
NOMESCO Finland
Local dermatologic skincare
5.3
9.4
19
37
N04.5
ICD-10 Finland
Nephrotic syndrome, diffuse mesangiocapillary glomerulonephritis
+∞
9.4
9
*
N04.3
ICD-10 Finland
Nephrotic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
9.4
9
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
9.2
90
463
C02EA02, ,
ATC
3.8
9.2
28
77
J01MA02
ATC
ciprofloxacin; systemic
1.9
9.0
173
1134
J01MA12
ATC
levofloxacin; systemic
2.2
9.0
93
489
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
9.0
123
719
O12.1
ICD-10 Finland
Gestational proteinuria
24.6
9.0
12
5
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
8.8
112
636
WZC30
NOMESCO Finland
Teaching
2.2
8.8
80
399
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
8.8
93
494
C02CA01
ATC
prazosin; oral
7.9
8.7
19
25
B01AB05
ATC
enoxaparin; parenteral
1.9
8.7
144
896
306
Kela drug reimbursment
Erythropoietin and darbepoetin
51.1
8.7
10
*
ZXD05
NOMESCO Finland
Urgent procedure
1.9
8.7
140
864
M01AE01
ATC
ibuprofen; systemic, rectal
0.5
8.7
282
3343
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.7
8.7
28
80
A10BK01
ATC
dapagliflozin; oral
3.0
8.6
39
138
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.0
8.6
39
138
WW500
NOMESCO Finland
Blood transfusion
3.6
8.5
29
86
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
20.5
8.5
12
6
WX204
NOMESCO Finland
Axillary plexus blockaced
3.9
8.5
25
67
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
8.5
133
813
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
8.4
52
218
JN4AD
NOMESCO Finland
Body CT examination
2.6
8.4
52
218
C09CA06
ATC
candesartan; oral
2.0
8.4
109
624
A12AA12
ATC
[U] calcium acetate
+∞
8.4
8
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
8.4
8
*
U88
ICPC
Glomerulonephritis/nephrosis
+∞
8.4
8
*
N06
ICD-10 Finland
Isolated proteinuria with specified morphological lesion
+∞
8.4
8
*
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
9.2
8.1
16
18
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
9.2
8.1
16
18
C03AA03
ATC
hydrochlorothiazide; oral
2.7
8.1
46
185
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.6
8.0
50
210
SPAT1262
SPAT
Handing over of treatment supplies
2.1
8.0
82
428
J01FF01
ATC
clindamycin; systemic
1.9
8.0
126
768
WX892
NOMESCO Finland
Monitored bed care
2.8
8.0
41
156
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.8
8.0
18
39
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
7.9
115
682
SPAT1255
SPAT
Intravenous administration of medicine
3.0
7.9
36
128
RS221, ,
NOMESCO Finland
8.7
7.9
16
19
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
7.9
44
175
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
7.8
80
418
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.3
7.7
30
97
A10BH05
ATC
linagliptin; oral
3.3
7.7
29
92
R4110
NOMESCO Finland
Physiotherapy
1.9
7.7
124
761
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
7.7
99
563
ZXE00
NOMESCO Finland
One hour or less
1.8
7.6
165
1109
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
7.6
47
197
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
7.5
67
331
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
7.4
37
139
UKC02
NOMESCO Finland
Cystoscopy
2.1
7.4
78
412
A10AB05
ATC
insulin aspart; parenteral
2.6
7.4
43
175
R2110
NOMESCO Finland
Giving the first information
3.2
7.4
30
100
N00.0
ICD-10 Finland
Acute nephritic syndrome, Minor glomerular abnormality
+∞
7.3
7
*
TK824
NOMESCO Finland
Replacement of peritoneal dialysis catheter extension tube
+∞
7.3
7
*
N05.8
ICD-10 Finland
Unspecified nephritic syndrome, other
+∞
7.3
7
*
E66.01
ICD-10 Finland
Obesity due to excess calories
2.6
7.2
43
177
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.7
7.2
38
147
L01AA01
ATC
cyclophosphamide; systemic
30.6
7.2
9
*
B07.9
ICD-10 Finland
Verruca simplex
3.9
7.2
21
56
M10.3
ICD-10 Finland
Gout due to impairment of renal function
20.4
7.2
10
5
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
3.3
7.1
27
86
N18
ICD-10 Finland
Chronic kidney disease
10.3
7.1
13
13
212
Kela drug reimbursment
Gout
6.5
7.0
17
27
R06.0
ICD-10 Finland
Dyspnoea
1.8
7.0
121
757
H26.3
ICD-10 Finland
Drug-induced cataract
14.1
6.9
11
8
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
6.9
54
252
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.9
6.9
20
53
T90
ICPC
Diabetes non-insulin dependent
1.9
6.9
104
622
R4180
NOMESCO Finland
Podiatric therapy
8.5
6.9
14
17
XW000
NOMESCO Finland
Bone marrow biopsy
3.2
6.9
27
88
XPX08
NOMESCO Finland
Intraoperative flow measurement
9.5
6.8
13
14
A12BA01
ATC
potassium chloride; oral
3.3
6.8
25
78
H02AB07
ATC
prednisone; oral
2.1
6.8
65
330
J01DB01
ATC
cefalexin; oral
2.0
6.8
341
2897
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
6.8
153
1035
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
6.7
65
331
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.8
6.7
20
54
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
6.7
55
262
RF210, ,
NOMESCO Finland
4.1
6.7
18
45
J01CF02
ATC
cloxacillin; systemic
5.7
6.7
18
33
R60.0
ICD-10 Finland
Localized oedema
2.2
6.7
57
276
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.4
6.7
24
74
TQW40
NOMESCO Finland
Remowal of suture of skin
2.7
6.6
36
141
A10AC01
ATC
insulin (human); parenteral
2.5
6.6
42
178
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.3
6.6
17
41
B01AB10
ATC
tinzaparin; parenteral
2.3
6.6
50
230
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.4
6.6
46
204
C07AB02
ATC
metoprolol; systemic
1.9
6.6
90
520
UJF32
NOMESCO Finland
Coloscopy
1.8
6.6
113
703
C08CA05
ATC
nifedipine; systemic
2.8
6.6
34
130
Z2446
NOMESCO Finland
Social worker
2.7
6.6
35
136
C10AA04
ATC
fluvastatin; oral
2.4
6.6
47
211
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
6.5
85
483
C09DA07
ATC
telmisartan and diuretics; oral
3.4
6.5
23
70
TPH07
NOMESCO Finland
Cathetrisation of artery
2.3
6.5
53
252
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
70.9
6.4
7
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.2
6.4
17
42
E78.29
ICD-10 Finland
Other mixed hyperlipidaemia
11.3
6.3
11
10
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
4.0
6.3
18
47
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.0
6.3
18
47
A02BC02
ATC
pantoprazole; systemic
1.7
6.3
278
2240
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
18.4
6.3
9
5
C08DB01
ATC
diltiazem; oral
3.0
6.3
27
93
N04.4
ICD-10 Finland
Nephrotic syndrome, diffuse endocapillary proliferative glomerulonephritis
+∞
6.3
6
*
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
+∞
6.3
6
*
L04AA17
ATC
[U] adalimumab
+∞
6.3
6
*
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
27.1
6.2
8
*
I50.0
ICD-10 Finland
Congestive heart failure
2.6
6.2
37
152
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.4
6.2
42
184
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
6.2
49
230
C09AA03
ATC
lisinopril; oral
3.0
6.2
27
94
TQW99
NOMESCO Finland
Other minor procedure on skin
2.8
6.2
30
111
A02BC01
ATC
omeprazole; systemic
1.8
6.1
117
751
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.5
6.1
21
63
N05CF01
ATC
zopiclone; oral
1.7
6.1
137
921

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
108
24
60.48
188.51
4.1
2.4
2.26
1.11
g/24h
2.47
77
13
257
403
15.12
181.25
18.1
4.3
1.14
1.01
mmol/l
9.06
251
370
181
234
12.94
143.47
8.9
3.2
149.38
72.78
ng/l
7.43
168
207
120
93
17.75
131.23
5.6
2.1
1.97
1.45
mg/l
3.77
114
83
94
69
17.32
104.93
3.0
4.3
—
—
—
0
0
105
96
14.30
103.10
3.7
3.9
68.26
103.43
mg/l
0.23
76
78
105
96
14.30
103.10
3.7
3.9
45.65
27.04
mg/l
2.07
77
78
104
94
14.43
102.84
3.7
3.8
0.77
2.48
ratio
—
5
12
64
27
27.84
91.26
2.0
2.5
—
—
—
0
0
191
426
7.45
90.36
7.0
2.1
23.12
22.72
%
0.14
178
363
195
456
7.18
87.60
6.7
2.0
2.17
2.37
g/l
4.95
189
418
125
210
8.09
76.23
3.3
2.6
—
—
—
0
0
267
962
5.98
71.43
9.8
3.1
635.74
106.76
mg/l
2.45
250
624
65
49
15.54
70.63
8.8
2.0
—
—
—
0
0
273
1017
5.92
69.76
12.2
3.5
75.19
6.34
mg/mmol
22.30
254
637
224
711
5.67
69.14
7.1
2.4
3.91
4.90
e6/l
0.68
214
638
273
1024
5.87
68.97
10.0
2.9
6.56
7.80
mmol/l
5.39
261
857
319
1410
6.46
64.99
14.5
4.4
34.18
35.86
g/l
7.05
314
1333
63
5
148.05
60.73
1.5
1.2
—
—
—
0
0
262
1039
5.13
59.26
9.1
3.1
21.81
120.99
e6/l
0.94
241
804
129
290
6.00
57.74
10.1
3.1
1.36
2.10
mmol/l
1.42
109
238
204
680
4.93
57.20
7.7
2.8
489.91
555.03
mosm/kgh2o
5.39
190
582
244
939
4.88
56.72
8.4
3.0
0.29
0.45
e6/l
0.75
224
706
231
876
4.69
54.14
6.0
2.7
386.05
6007.06
umol/l
3.05
221
757
59
62
10.93
51.61
8.0
2.6
—
—
—
0
0
323
1619
5.49
51.44
24.0
6.2
1.22
1.21
mmol/l
0.50
287
1385
86
145
7.22
51.12
2.4
2.2
1.64
1.58
g/l
0.17
79
129
267
1200
4.43
48.05
10.5
3.6
74.59
94.97
e6/l
0.17
245
858
237
983
4.29
47.62
15.4
3.7
7.39
7.40
ph
2.31
69
187
163
516
4.56
47.43
2.4
2.0
29.69
29.78
s
0.06
163
499
225
915
4.19
46.13
8.0
2.9
—
—
—
0
0
278
1321
4.35
45.41
4.0
2.2
70.80
76.43
nmol/l
2.73
272
1171
92
206
5.45
40.36
7.2
3.3
7.40
7.42
ph
1.02
30
22
92
209
5.37
39.67
7.2
3.2
4.99
5.06
kpa
0.42
92
202
286
1478
4.01
39.24
18.4
5.4
1.23
1.21
mmol/l
1.94
281
1340
152
516
4.07
39.19
5.0
3.2
0.81
0.82
mmol/l
0.16
146
492
103
263
4.88
38.62
11.5
7.7
—
—
—
0
0
286
1492
3.95
38.35
11.5
5.7
0.71
0.66
%
0.60
275
1399
48
57
9.39
38.11
5.0
2.1
—
—
—
0
0
103
269
4.76
37.49
4.7
2.8
73.38
71.64
e9/l
0.18
78
207
289
1536
3.90
37.26
11.4
5.8
2.88
2.75
%
0.43
279
1446
123
372
4.28
36.97
5.1
2.7
1.95
1.84
%
0.60
118
337
289
1545
3.87
36.72
11.7
6.0
8.49
8.62
%
0.33
278
1459
290
1560
3.85
36.35
11.2
5.6
59.38
57.49
%
1.80
278
1477
298
1639
3.90
35.93
11.0
5.7
0.05
0.04
e9/l
1.59
276
1442
297
1637
3.86
35.53
11.0
5.7
0.62
0.59
e9/l
1.44
275
1438
287
1549
3.76
35.44
11.6
6.3
—
—
—
0
0
290
1583
3.76
35.01
11.7
5.9
25.50
27.52
%
2.27
280
1498
126
406
4.02
34.46
3.0
1.5
—
—
—
0
0
301
1700
3.81
34.07
11.3
5.9
0.20
0.19
e9/l
0.52
279
1516
47
64
8.15
33.35
3.3
1.2
137.89
105.31
u/ml
—
9
13
296
1677
3.67
32.82
11.4
5.7
2.35
1.92
e9/l
0.42
279
1517
56
95
6.66
32.58
4.3
2.8
36.28
38.41
g/l
1.63
56
84
59
112
5.98
30.62
7.0
3.5
0.96
0.15
g/l
2.82
46
40
34
35
10.49
29.82
1.1
1.3
—
—
—
0
0
47
73
7.13
29.64
3.3
1.2
—
—
—
0
0
43
63
7.50
28.56
1.7
1.8
—
—
—
0
0
141
549
3.38
28.28
5.9
2.9
1.44
2.05
e6/l
0.74
100
299
280
1619
3.24
28.20
10.6
4.9
0.00
0.00
estimate
-0.00
94
311
137
525
3.40
28.19
3.0
1.6
—
—
—
0
0
34
38
9.66
28.09
2.2
2.6
—
—
—
0
0
348
2302
4.17
28.00
11.8
4.1
—
—
—
0
0
312
1928
3.49
27.94
14.3
9.2
4.45
4.14
e9/l
1.85
292
1698
145
579
3.31
27.85
5.3
2.7
0.61
0.96
e6/l
1.50
104
326
42
62
7.42
27.69
5.3
2.2
15.99
16.20
%
0.09
37
28
280
1641
3.17
27.11
8.0
3.6
0.01
0.00
estimate
0.49
89
295
277
1622
3.13
26.69
8.1
3.6
0.00
0.00
estimate
0.50
97
334
122
457
3.36
25.78
1.4
1.4
564.80
509.70
titre
0.10
25
101
41
69
6.48
23.88
1.9
1.2
235.19
260.55
u/ml
0.18
26
40
246
1406
2.84
23.76
7.0
2.6
212.05
129.66
ug/l
3.95
239
1295
78
229
3.96
23.68
1.9
1.5
1.56
1.51
g/l
0.03
71
211
37
58
6.91
23.03
1.1
1.5
—
—
—
0
0
184
918
2.80
22.92
6.5
4.1
—
—
—
0
0
250
1471
2.76
22.31
22.6
9.6
0.00
0.00
e9/l
0.03
222
1217
81
254
3.72
22.30
7.5
5.1
0.12
0.15
%
0.15
34
87
49
106
5.11
21.87
1.6
1.2
—
—
—
0
0
258
1564
2.72
21.34
19.3
12.8
1.18
1.26
inr
1.04
107
469
78
247
3.66
21.10
6.8
4.8
0.58
0.39
%
0.49
31
86
78
247
3.66
21.10
7.3
5.0
0.16
0.15
%
0.02
31
79
225
1290
2.63
20.62
6.7
3.4
5.80
5.88
ph
—
10
104
82
274
3.48
20.40
7.4
4.9
1.03
0.87
%
0.18
35
108
186
992
2.59
19.55
4.0
2.9
—
—
—
0
0
38
74
5.55
19.01
5.5
2.0
—
—
—
0
0
116
495
2.86
18.91
2.7
1.9
—
—
—
0
0
27
14
20.53
18.44
1.9
1.4
—
—
—
0
0
35
65
5.79
18.40
8.9
2.9
2.21
2.32
mmol/l
0.08
22
44
131
606
2.70
18.20
3.2
1.8
—
—
—
0
0
167
898
2.44
16.66
7.7
3.2
—
—
—
0
0
24
13
19.51
16.20
2.6
2.0
—
—
—
0
0
266
1773
2.39
15.98
7.7
6.3
11.17
11.21
umol/l
0.01
260
1688
24
36
7.01
15.47
1.4
1.2
—
—
—
0
0
153
813
2.40
15.45
3.0
2.0
2.99
3.14
mg/l
0.38
137
693
26
21
13.12
15.08
2.6
2.0
750.85
396.55
ml
2.76
20
11
286
2012
2.36
14.51
9.8
4.4
6.87
6.65
mmol/l
1.19
274
1873
307
2235
2.44
14.26
8.1
4.2
286.88
963.69
e6/l
—
8
36
176
1021
2.26
14.23
2.9
2.1
141.48
213.07
u/l
1.69
169
960
18
6
31.25
13.99
1.0
1.0
—
—
—
0
0
178
1076
2.15
12.62
3.5
2.4
63.34
61.51
u/l
0.14
172
1007
17
7
25.22
12.56
1.0
1.0
—
—
—
0
0
17
7
25.22
12.56
1.0
1.1
—
—
—
0
0
34
88
4.12
12.07
3.3
2.1
421.60
80.01
ug/min
2.09
25
54
148
849
2.16
11.86
10.7
6.7
—
—
—
0
0
54
193
3.07
11.79
8.1
2.6
0.18
0.18
e6/l
0.00
54
185
153
893
2.13
11.69
8.8
3.8
0.14
0.00
estimate
1.22
64
305
178
1100
2.08
11.69
6.7
3.2
2.32
2.35
mmol/l
1.86
170
963
71
300
2.65
11.37
6.8
6.5
1.25
1.35
mmol/l
0.27
71
290
46
155
3.21
11.08
8.4
3.3
—
—
—
0
0
63
256
2.72
10.88
2.3
1.4
—
—
—
0
0
66
277
2.64
10.69
10.3
3.3
—
—
—
0
0
113
609
2.18
10.42
2.3
1.7
1273.21
1179.09
nmol/l
0.39
97
465
135
786
2.06
10.13
1.8
1.5
20.67
21.33
nmol/l
0.17
128
675
318
2498
2.17
10.13
8.2
3.9
20.09
11.93
mm/h
10.77
309
2294
41
136
3.24
10.12
2.7
1.6
—
—
—
0
0
33
95
3.69
10.11
4.5
3.1
—
—
—
0
0
70
314
2.48
9.85
1.9
1.8
350.49
370.65
nmol/l
0.32
65
287
170
1083
1.97
9.85
3.5
2.3
—
—
—
0
0
122
695
2.07
9.65
1.9
1.4
2.79
2.51
g/l
0.59
89
434
21
44
4.97
9.64
2.8
2.1
—
—
—
0
0
65
288
2.49
9.38
1.6
1.4
—
—
—
0
0
17
16
11.02
9.37
1.6
1.5
3.82
0.78
u/field
—
11
9
40
138
3.10
9.25
3.1
2.7
—
—
—
0
0
45
168
2.88
9.07
5.7
2.3
0.74
0.65
%
1.37
45
168
194
1323
1.88
8.91
2.3
1.9
102.20
93.40
pmol/l
2.08
116
699
76
378
2.24
8.41
6.3
7.0
11.12
12.00
kpa
0.84
71
362
8
0
+∞
8.36
4.5
0.0
16.09
—
mmol/l
—
8
0
8
0
+∞
8.36
3.3
0.0
1.28
—
g/l
—
8
0
8
0
+∞
8.36
4.5
0.0
349.88
—
umol/l
—
8
0
77
389
2.20
8.19
2.4
1.6
—
—
—
0
0
16
18
9.20
8.11
1.6
1.7
—
—
—
0
0
124
752
1.93
8.01
7.0
3.5
—
—
—
0
0
59
271
2.37
7.84
10.0
3.3
—
—
—
0
0
15
17
9.11
7.60
1.3
1.2
179.47
163.39
mmol/24h
0.16
15
17
74
379
2.16
7.58
6.3
7.0
0.61
1.13
mmol/l
0.61
58
299
187
1309
1.78
7.52
5.6
3.7
42.77
40.40
ng/l
0.13
155
924
41
164
2.66
7.26
8.3
3.6
—
—
—
0
0
216
1602
1.73
6.89
3.5
2.5
—
—
—
0
0
40
164
2.59
6.75
6.9
9.4
—
—
—
0
0
146
980
1.76
6.59
4.4
3.1
4740.05
1138.35
ng/l
3.63
135
833
34
130
2.76
6.57
6.5
4.4
1.67
1.55
%
0.36
34
120
163
1131
1.73
6.53
4.0
3.2
49.40
31.94
u/l
0.57
152
1082
21
62
3.51
6.22
6.0
1.6
78.29
60.42
%
3.48
21
62
27
95
2.97
6.06
1.2
1.2
—
75.00
—
0
6
364
3203
2.11
5.99
6.2
4.0
1.66
1.30
mmol/l
3.04
349
2940
60
314
2.06
5.77
6.9
7.6
113.40
122.05
g/l
2.14
60
306
32
128
2.63
5.68
6.8
4.5
0.86
0.89
%
0.22
32
119
377
3378
2.27
5.66
37.6
13.8
18.35
23.48
mg/l
3.30
340
2652
132
893
1.70
5.64
1.8
1.6
1.74
1.42
mmol/l
0.76
117
742
16
42
3.92
5.59
3.0
2.1
89.69
90.41
%
0.17
16
42
16
42
3.92
5.59
1.1
1.2
—
—
—
0
0
19
57
3.45
5.51
1.9
1.5
—
—
—
0
0
352
3096
1.90
5.28
9.7
5.7
40.92
39.80
mmol/mol
1.15
341
2886
5
0
+∞
5.22
5.6
0.0
70.66
—
g/mol
—
5
0
369
3302
2.06
5.19
6.8
4.4
1.39
1.45
mmol/l
1.42
357
3045
14
27
5.33
5.12
5.4
1.7
10.46
10.70
%
0.08
14
27
20
66
3.13
5.01
1.3
1.8
—
—
—
0
0
20
67
3.09
4.89
1.9
1.2
—
—
—
0
0
369
3318
2.01
4.87
6.9
4.4
4.54
4.63
mmol/l
1.01
357
3076
14
29
4.96
4.85
1.1
1.2
—
—
—
0
0
16
48
3.43
4.65
2.9
3.0
—
—
—
0
0
11
19
5.92
4.47
2.4
5.1
—
—
—
0
0
39
192
2.14
4.40
1.3
1.3
—
—
—
0
0
103
692
1.65
4.39
1.9
1.7
465.80
6956961.22
pmol/l
0.50
91
575
24
95
2.62
4.38
7.0
4.6
—
—
—
0
0
94
618
1.67
4.35
6.1
3.5
100.32
249.45
ng/l
1.22
78
479
372
3381
1.97
4.35
7.2
4.9
2.57
2.76
mmol/l
3.78
361
3116
14
41
3.50
4.22
1.1
1.2
—
—
—
0
0
12
25
4.91
4.21
1.9
2.4
0.67
3.00
u/field
—
6
7
42
217
2.04
4.19
5.5
4.0
—
—
—
0
0
292
2507
1.56
4.05
4.3
3.9
14.78
14.82
pmol/l
0.09
272
2266
16
53
3.10
4.01
2.9
2.7
3.88
3.98
mmol/l
0.43
16
53
16
53
3.10
4.01
2.9
2.7
—
—
—
0
0
16
53
3.10
4.01
2.9
2.7
104.88
105.64
mmol/l
0.20
16
53
278
2368
1.53
3.94
5.0
3.9
—
—
—
0
0
8
11
7.39
3.87
1.9
1.0
1351.38
1418.82
miu/ml
—
8
11
107
750
1.57
3.79
1.4
1.2
2.18
1.63
u/ml
0.30
37
208
13
34
3.91
3.72
1.2
1.1
—
—
—
0
0
66
411
1.72
3.71
2.1
2.2
175.33
117.50
ug/g
0.55
59
325
128
939
1.53
3.68
1.6
1.4
—
—
—
0
0
40
214
1.96
3.64
3.8
2.7
—
—
—
0
0
13
35
3.80
3.62
1.6
1.4
—
—
nmol/l
—
0
0
54
320
1.79
3.60
2.5
1.7
—
—
—
0
0
7
9
7.89
3.57
1.3
1.4
—
—
—
0
0
32
161
2.07
3.45
2.3
2.4
—
—
—
0
0
13
37
3.59
3.43
1.1
1.4
—
—
—
0
0
383
3569
1.95
3.34
23.7
10.4
25.49
26.80
u/l
0.48
377
3444
63
399
1.68
3.33
1.3
1.3
—
—
—
0
0
16
60
2.73
3.26
1.1
1.1
—
—
—
0
0
13
44
3.02
3.16
1.2
1.4
—
—
—
0
0
9
20
4.58
3.13
4.8
3.0
—
—
—
0
0
52
318
1.73
3.12
18.3
3.9
—
—
—
0
0
62
399
1.65
3.09
3.2
2.7
7.30
7.77
umol/l
0.14
54
350
19
81
2.41
3.03
3.4
2.3
—
—
—
0
0
7
209
0.32
3.02
1.1
1.4
—
—
—
0
0
11
31
3.62
3.01
4.5
2.7
—
—
—
0
0
11
32
3.50
2.92
1.4
1.2
—
—
—
0
0
6
9
6.74
2.87
2.0
1.4
—
—
—
0
0
6
9
6.74
2.87
1.0
1.6
182.33
54.11
nmol/24h
—
6
9
128
983
1.44
2.83
5.8
3.9
—
—
—
0
0
103
759
1.47
2.82
2.1
1.8
1.82
1.14
mg/l
0.57
84
588
8
18
4.51
2.81
1.1
1.1
—
—
—
0
0
8
18
4.51
2.81
2.3
1.4
—
—
—
0
0
9
23
3.98
2.79
1.6
1.8
46.07
35.83
%
—
9
23
5
6
8.41
2.75
1.0
1.0
—
—
—
0
0
13
48
2.76
2.74
2.2
1.5
—
—
—
0
0
10
29
3.51
2.71
3.0
1.3
—
—
—
0
0
6
10
6.07
2.70
4.2
5.1
57.50
51.90
%
—
6
10
16
68
2.41
2.59
1.1
1.1
—
—
—
0
0
5
7
7.21
2.55
1.8
1.3
—
—
—
0
0
19
88
2.21
2.55
1.2
1.2
—
—
—
0
0
7
16
4.43
2.48
1.0
2.2
1108.00
818.81
u/ml
—
7
16
8
21
3.86
2.47
1.1
1.0
—
—
—
0
0
15
64
2.39
2.41
6.0
3.3
59.67
57.30
%
0.29
15
64
333
3058
1.45
2.36
5.2
4.6
1.94
2.30
mu/l
0.43
318
2782
12
47
2.60
2.29
2.9
4.1
—
—
—
0
0
27
150
1.86
2.26
1.1
1.2
—
—
—
0
0
16
320
0.48
2.25
1.2
1.4
—
—
—
0
0
59
407
1.52
2.22
1.7
1.4
—
—
—
0
0
12
48
2.54
2.20
10.6
5.9
15.13
11.16
mg/l
2.03
12
43
12
49
2.49
2.12
1.9
1.5
—
—
—
0
0
8
25
3.24
2.10
1.6
2.0
1.16
1.03
e9/l
—
8
20
56
387
1.52
2.09
1.4
1.3
—
—
—
0
0
5
10
5.05
2.07
1.2
1.3
—
—
—
0
0
15
70
2.19
2.00
3.9
1.6
—
—
—
0
0
19
99
1.96
1.93
2.5
2.1
3703.17
3663.53
u/l
—
6
36
6
17
3.56
1.84
1.3
1.2
—
—
—
0
0
16
81
2.01
1.77
1.2
1.2
—
—
—
0
0
372
3536
1.50
1.76
34.6
12.9
—
—
—
0
0
7
24
2.95
1.73
1.6
1.0
—
—
—
0
0
10
40
2.54
1.67
1.0
1.2
—
—
—
0
0
13
62
2.13
1.67
5.2
3.0
4.40
4.26
e9/l
0.07
13
62
13
62
2.13
1.67
1.1
1.1
22.48
17.56
u/l
0.45
13
54
11
49
2.28
1.65
2.1
3.1
—
—
—
0
0
8
32
2.53
1.60
1.1
1.6
—
—
—
0
0
7
26
2.72
1.58
1.1
1.0
—
—
—
0
0
5
15
3.36
1.52
1.4
1.2
—
—
—
0
0
6
22
2.75
1.44
3.7
1.7
10.10
9.07
mmol/l
—
6
22
6
22
2.75
1.44
2.2
4.5
—
—
—
0
0
154
1333
1.25
1.35
2.2
2.0
—
—
—
0
0
61
469
1.35
1.32
1.2
1.2
—
—
—
0
0
51
389
1.35
1.17
1.7
1.7
—
—
—
0
0
386
3741
1.46
1.15
51.7
20.5
38.62
40.38
%
5.81
365
3534
13
73
1.81
1.12
2.3
1.9
3.75
4.84
mmol/24h
0.78
13
65
35
253
1.42
1.11
1.3
1.2
—
—
—
0
0
386
3744
1.44
1.11
51.9
20.4
4.29
4.51
e12/l
9.38
381
3654
14
86
1.65
0.92
2.0
1.3
—
—
—
0
0
6
29
2.08
0.89
2.2
1.6
—
—
—
0
0
6
29
2.08
0.89
1.2
1.1
—
—
—
0
0
8
42
1.92
0.89
1.0
1.1
—
—
—
0
0
9
150
0.59
0.80
2.1
1.8
—
—
—
0
0
139
1246
1.17
0.80
4.0
5.0
2.27
2.56
ug/l
0.35
127
1129
6
34
1.78
0.76
1.3
1.4
—
—
—
0
0
16
109
1.49
0.72
3.8
1.3
—
—
—
0
0
42
338
1.27
0.71
1.4
1.5
—
—
—
0
0
16
110
1.47
0.69
3.8
1.3
—
—
—
0
0
16
110
1.47
0.69
3.8
1.3
—
—
—
0
0
16
111
1.46
0.67
3.7
1.4
—
—
—
0
0
5
28
1.80
0.66
1.2
1.5
—
—
—
0
0
15
104
1.46
0.63
3.8
1.3
—
—
—
0
0
82
722
1.17
0.59
9.3
3.9
1.02
1.02
kg/l
0.32
14
93
6
37
1.63
0.55
1.0
1.8
—
—
—
0
0
240
2281
1.12
0.54
5.0
3.2
70.19
50.07
u/l
1.41
226
2141
18
134
1.36
0.54
8.1
4.4
—
—
—
0
0
17
222
0.76
0.48
1.1
1.2
25.17
150.24
iu/ml
—
6
91
7
46
1.53
0.48
1.6
1.1
—
—
—
0
0
7
46
1.53
0.48
1.6
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
4.9
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
290
2814
1.10
0.38
42.2
18.0
330.11
332.89
g/l
5.54
290
2799
15
116
1.30
0.37
1.3
1.2
—
—
—
0
0
5
37
1.36
0.37
2.8
1.6
76.44
14.86
ug/l
—
5
37
64
576
1.13
0.37
1.2
1.3
96.99
35.34
iu/ml
0.68
21
188
26
217
1.21
0.36
1.1
1.3
—
37.41
—
0
14
12
90
1.34
0.36
1.3
1.8
138.08
230.04
pmol/l
3.32
12
83
68
617
1.12
0.35
2.9
3.0
2.49
2.45
mmol/l
1.82
60
552
6
45
1.34
0.34
1.2
1.1
—
11.88
—
0
5
6
46
1.31
0.33
3.0
2.9
6.35
3.80
nmol/l
—
6
46
28
240
1.18
0.31
1.8
2.5
—
21.13
—
0
13
61
555
1.12
0.30
1.3
1.3
46.72
14.13
u/ml
0.52
15
215
29
252
1.16
0.28
1.3
1.4
—
—
—
0
0
6
84
0.71
0.24
1.2
1.1
—
—
—
0
0
5
39
1.29
0.23
1.8
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
19.97
—
0
6
0
10
0.00
0.21
0.0
2.1
—
17.46
—
0
10
0
12
0.00
0.21
0.0
1.3
—
5543.40
—
0
5
5
43
1.16
0.21
1.8
1.8
—
—
—
0
0
12
144
0.83
0.20
1.2
1.1
—
—
—
0
0
78
738
1.07
0.18
3.3
3.0
1.25
0.79
ug/l
1.01
61
484
331
3267
1.07
0.18
6.4
4.5
6.17
5.96
mmol/l
1.77
313
2979
28
307
0.91
0.16
1.3
1.4
—
—
—
0
0
125
1210
1.05
0.14
4.8
2.8
—
—
—
0
0
8
97
0.82
0.14
15.3
10.4
—
—
—
0
0
10
86
1.17
0.11
1.1
1.1
—
—
—
0
0
6
56
1.07
0.08
1.0
1.1
—
—
—
0
0
21
195
1.08
0.08
1.2
1.2
—
—
—
0
0
14
138
1.01
0.00
1.0
1.1
—
—
—
0
0
35
345
1.02
0.00
3.3
4.1
4.20
39.24
ug/l
0.91
25
290
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
1.84
—
0
6
0
5
0.00
0.00
0.0
1.0
—
8.08
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.1
—
5.82
—
0
8
13
130
1.00
-0.00
1.5
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
17.97
—
0
7
0
7
0.00
-0.00
0.0
2.3
—
8165.00
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
42.71
—
0
7
5
50
1.00
-0.00
1.2
4.8
269.20
361.48
umol/l
—
5
44
6
65
0.92
-0.00
1.2
1.3
—
—
—
0
0
6
61
0.98
-0.00
1.5
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint N14_ISOLPROTEINURIA and mortality.

Females

Parameter HR [95% CI] p-value
N14_ISOLPROTEINURIA 2.374 [1.89, 2.99] < 0.001
Birth year 0.997 [0.99, 1.01] 0.498

During the follow-up period (1.1.1998 — 31.12.2019), 298 out of 1035 females with N14_ISOLPROTEINURIA died.

Males

Parameter HR [95% CI] p-value
N14_ISOLPROTEINURIA 2.47 [2.05, 2.98] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 335 out of 1068 males with N14_ISOLPROTEINURIA died.

Mortality risk

Mortality risk for people of age

years, who have N14_ISOLPROTEINURIA.

N-year risk Females Males
1 0.206% 0.406%
5 1.226% 2.37%
10 3.842% 6.592%
15 7.307% 12.895%
20 13.146% 21.264%

Relationships between endpoints

↥

Index endpoint: N14_ISOLPROTEINURIA – Isolated proteinuria with specified morphological lesion

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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