Vertical strabismus

H7_VERTISTRAB

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H50.2
  • Hospital discharge: ICD-9 3783
  • Hospital discharge: ICD-8 37302
  • Cause of death: ICD-10 H50.2
  • Cause of death: ICD-9 3783
  • Cause of death: ICD-8 37302

2 out of 7 registries used, show all original rules.

1257

4. Check minimum number of events

None

1257

5. Include endpoints

None

1257

6. Filter based on genotype QC (FinnGen only)

1257

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H50
Name in latin
Strabismus verticalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9645 5200 4422
Only index persons 8778 4806 3972
Unadjusted period prevalence (%)
Whole population 0.14 0.15 0.12
Only index persons 0.17 0.18 0.15
Median age at first event (years)
Whole population 28.68 28.55 28.72
Only index persons 30.56 30.52 30.61

-FinnGen-

Key figures

All Female Male
Number of individuals 1257 758 499
Unadjusted period prevalence (%) 0.24 0.26 0.22
Median age at first event (years) 47.02 42.89 53.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1143
Matched controls
11430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H50.2
ICD-10 Finland
Vertical strabismus
4503599627370496.0
323.0
902
*
H53.2
ICD-10 Finland
Diplopia
41.2
202.3
255
79
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
181.2
169
*
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
174.6
163
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
1463.8
136.3
130
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
135.1
127
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
1325.4
124.4
119
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
121.0
114
*
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
115.6
109
*
3503
FHL
Single muscle retroposition
+∞
101.6
96
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.0
90.4
282
594
H50.52
ICD-10 Finland
Exophoria
443.9
84.2
83
*
H50.31
ICD-10 Finland
Intermittent exotropia
+∞
72.7
69
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
71.6
68
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
64.2
61
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
60.7
63.5
74
13
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
63.1
60
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.4
47.8
273
969
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
47.2
45
*
H50.8
ICD-10 Finland
Other specified strabismus
+∞
41.9
40
*
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
40.9
39
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
7.8
39.8
95
132
H50.9
ICD-10 Finland
Strabismus, unspecified
185.6
34.9
36
*
XCK00
NOMESCO Finland
Perimetry
4.4
34.3
132
328
H52.0
ICD-10 Finland
Hypermetropia
35.1
34.3
44
13
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
33.5
32
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
32.9
496
2966
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
41.4
32.3
40
10
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
31.4
30
*
CE2W4
NOMESCO Finland
Eye movement mapping
159.1
29.8
31
*
WX140
NOMESCO Finland
Parabulbar anesthesy
5.2
29.6
95
195
H50.4
ICD-10 Finland
Other and unspecified heterotropia
299.2
28.9
29
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
19.4
28.4
43
23
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
48.4
27.6
33
7
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
27.2
26
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.6
26.8
130
396
H52.1
ICD-10 Finland
Myopia
11.6
24.8
46
41
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.0
24.2
393
2343
H53.0
ICD-10 Finland
Amblyopia ex anopsia
19.5
24.0
36
19
H03BB01
ATC
carbimazole; oral
4.8
23.9
82
181
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
23.0
22
*
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
23.0
22
*
H50.50
ICD-10 Finland
Alternating hyperphoria
122.5
22.7
24
*
H52.2
ICD-10 Finland
Astigmatism
21.2
22.6
33
16
3504
FHL
Retroposition of two muscles
+∞
21.9
21
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
6.1
21.9
60
102
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
20.9
20
*
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
48.9
20.2
24
5
H05.2
ICD-10 Finland
Exophthalmic conditions
36.5
19.9
25
7
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
18.8
18
*
ZXA00
NOMESCO Finland
Right side
1.9
18.8
316
1875
H50.51
ICD-10 Finland
Esophoria
71.1
18.8
21
*
N07AA02
ATC
pyridostigmine; systemic
19.1
18.7
28
15
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.3
18.7
97
311
H062, E050
ICD-10 Finland
NA
53.4
18.0
21
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
17.7
17
*
3501
FHL
Myotomy or tenotomy
+∞
17.7
17
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
17.7
17
*
AA1AD
NOMESCO Finland
CT of head and brain
2.0
17.1
257
1453
3505
FHL
Single muscle resection
+∞
16.7
16
*
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
16.7
16
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.0
16.7
54
113
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.5
15.8
131
563
F95
ICPC
Strabismus
60.9
15.8
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
15.7
314
1960
ZXA10
NOMESCO Finland
Bilateral
2.0
15.7
213
1153
G70.0
ICD-10 Finland
Myasthenia gravis
19.5
15.6
23
12
ZXA05
NOMESCO Finland
Left side
1.9
15.3
286
1740
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.3
14.9
146
683
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.6
14.8
115
477
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
14.6
14
*
3507
FHL
Retroposition and resection
151.8
14.5
15
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.5
13.7
107
446
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
9.8
13.2
26
27
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
12.5
12
*
3510
FHL
Cardiac surgery on three or more muscles
+∞
12.5
12
*
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
12.5
12
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
12.5
12
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
131.4
12.5
13
*
H03AA01
ATC
levothyroxine sodium; systemic
1.8
12.2
257
1612
108
Kela drug reimbursment
Myasthenia gravis
16.1
12.2
19
12
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
21.5
12.0
17
8
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
12.0
101
437
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
11.9
134
665
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
11.9
119
563
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
8.0
11.9
26
33
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
65.6
11.6
13
*
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
11.5
11
*
H02.4
ICD-10 Finland
Ptosis of eyelid
4.2
10.6
39
95
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
10.6
75
297
TAB00
NOMESCO Finland
Lumbar puncture
3.1
10.4
57
192
H25.0
ICD-10 Finland
Senile incipient cataract
2.8
10.4
65
238
CS494
NOMESCO Finland
Other visual field testing
4.1
10.2
38
94
H04.10
ICD-10 Finland
Dry eye syndrome
2.2
10.0
108
526
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.5
9.7
22
30
WX002
NOMESCO Finland
Sedation and analgesia
1.7
9.5
201
1253
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
9.5
306
2143
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
9.4
9
*
3508
FHL
Transposition or anteposition
+∞
9.4
9
*
H53.3
ICD-10 Finland
Other disorders of binocular vision
13.8
9.2
15
11
H26.4
ICD-10 Finland
After-cataract
2.2
9.1
90
424
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
9.0
83
378
CAC10
NOMESCO Finland
Reconstruction of orbital wall using bone graft or plate
37.0
9.0
11
*
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
4.6
9.0
30
67
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.5
8.8
40
118
WX402
NOMESCO Finland
General anaesthesia
1.7
8.6
172
1055
CAC44
NOMESCO Finland
Combined decompression of orbit
90.7
8.4
9
*
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
8.3
8
*
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
8.3
8
*
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
8.3
8
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
8.2
254
1753
R42
ICD-10 Finland
Dizziness and giddiness
1.6
8.2
211
1388
H33.0
ICD-10 Finland
Retinal detachment with retinal break
3.5
8.1
36
105
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
8.0
104
548
BAA60
NOMESCO Finland
Total thyroidectomy
3.5
7.4
33
97
CAC20
NOMESCO Finland
Lateral decompression of orbit
80.6
7.4
8
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.8
7.4
29
77
CEC85
NOMESCO Finland
Combined correction of cyclodeviation
+∞
7.3
7
*
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
7.3
7
*
CEE00
NOMESCO Finland
Posterior fixation suture of extraocular muscle
+∞
7.3
7
*
XA800
NOMESCO Finland
Neuropsychological investigation
2.7
7.2
47
179
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.1
525
4314
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.9
7.0
41
146
S02.30
ICD-10 Finland
Fracture of orbital floor, closed
7.0
7.0
16
23
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
7.0
66
305
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.9
152
956
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
6.7
6.8
16
24
H50.59
ICD-10 Finland
Heterophor UNS
40.3
6.8
8
*
WX110
NOMESCO Finland
Local anesthesy
1.4
6.8
720
6280
A02BC05
ATC
esomeprazole; systemic
1.4
6.7
385
3009
N06AX11
ATC
mirtazapine; oral
1.5
6.7
310
2329
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
4.9
6.7
20
41
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
22.7
6.7
9
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
6.6
209
1446
R20.2
ICD-10 Finland
Paraesthesia of skin
2.1
6.6
69
337
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.1
6.5
33
109
H50.39
ICD-10 Finland
Intermittent heterotropia
70.2
6.4
7
*
CA1AD
NOMESCO Finland
Orbita CT
14.4
6.4
10
7
J01DB01
ATC
cefalexin; oral
1.4
6.4
857
7747
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.3
131
809
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
6.3
121
732
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
11.1
6.3
11
10
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.9
6.3
83
444
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
4.3
6.2
21
49
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.2
399
3178
R01AD09
ATC
mometasone; nasal
1.4
6.1
447
3634
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
6.1
198
1375
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
12.6
6.1
10
8
104
Kela drug reimbursment
Thyroid insufficiency
2.0
6.1
74
385
R62.0
ICD-10 Finland
Delayed milestone
8.6
6.1
12
14
CKC60
NOMESCO Finland
Local buckling of sclera using implant
10.1
6.0
11
11
S18
ICPC
Laceration/cut
1.4
6.0
394
3144

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
63
60
11.00
58.07
1.2
1.1
3.7
1.8
nmol/l
0.35
16
12
106
273
4.15
37.19
3.4
1.9
6.5
4.9
iu/l
0.57
61
101
649
4877
1.68
17.96
6.9
6.7
1.2
1.2
mmol/l
0.41
551
4159
589
4420
1.63
15.60
6.1
6.0
1.2
1.2
mmol/l
0.55
543
4043
61
212
2.97
13.49
2.0
1.8
—
—
—
0
0
408
2884
1.61
13.25
2.2
2.1
219.4
223.8
u/l
0.03
390
2720
128
650
2.08
12.50
4.8
3.3
4.5
4.6
pmol/l
0.48
116
573
507
3877
1.52
11.17
8.5
8.8
1.2
1.2
inr
0.37
142
1159
256
1721
1.61
9.82
1.8
1.7
1055.3
1180.0
nmol/l
1.50
190
1311
701
5818
1.46
9.79
5.0
4.7
6.5
6.6
mmol/l
0.86
663
5423
1051
9502
1.65
9.64
6.3
4.7
1.8
2.0
mu/l
0.84
979
8768
509
3987
1.46
9.53
2.0
1.9
97.7
95.1
pmol/l
0.63
266
2078
911
8017
1.50
9.01
5.6
4.0
14.9
14.7
pmol/l
1.37
844
7352
530
4231
1.44
8.76
4.5
4.7
36.3
35.8
g/l
1.15
495
3947
385
2904
1.47
8.55
4.1
3.9
7.4
7.4
ph
0.61
78
556
55
231
2.44
8.50
2.0
1.8
1046.6
632.5
e6/l
0.23
43
182
55
231
2.44
8.50
2.0
1.7
19.2
15.0
e6/l
0.18
43
174
35
116
3.08
8.47
2.5
2.3
—
—
—
0
0
158
975
1.71
8.38
2.2
2.0
358.9
377.2
nmol/l
0.59
143
900
33
108
3.11
8.17
2.4
1.9
—
—
—
0
0
53
224
2.43
8.09
1.2
1.5
3.7
3.7
mmol/l
0.01
48
212
1114
10335
1.68
7.92
15.4
13.4
21.7
23.1
mg/l
0.61
900
8101
876
7728
1.44
7.91
7.4
7.3
79.7
78.6
u/l
0.17
831
7275
1121
10437
1.68
7.60
17.8
15.1
139.7
139.6
mmol/l
0.68
1101
10164
220
1514
1.55
7.48
1.9
2.2
30.1
29.7
s
0.33
212
1471
1122
10461
1.68
7.41
18.0
15.2
4.0
4.0
mmol/l
0.12
1103
10177
604
5031
1.39
7.40
6.3
6.0
28.3
28.4
%
0.11
560
4725
593
4961
1.37
6.90
5.9
5.8
57.2
56.8
%
0.30
551
4683
333
2530
1.43
6.87
4.0
3.9
88.3
91.0
%
1.13
325
2461
804
7080
1.38
6.67
5.1
4.1
—
—
—
0
0
583
4896
1.36
6.48
6.5
6.2
8.5
8.5
%
0.14
549
4616
580
4868
1.36
6.47
6.2
5.9
2.8
2.8
%
0.16
543
4562
769
6740
1.36
6.47
5.5
4.3
3545.5
2785.6
e6/l
0.11
13
102
221
1571
1.49
6.41
2.7
3.4
0.8
0.8
mmol/l
0.07
207
1479
624
5303
1.35
6.38
6.0
5.8
1.9
1.9
e9/l
0.13
536
4684
431
3470
1.37
6.21
6.0
5.8
—
—
—
0
0
561
4713
1.34
6.10
6.3
6.0
0.7
0.7
%
0.44
525
4426
184
1290
1.50
5.68
5.2
5.7
1.1
1.1
mmol/l
0.05
172
1203
621
5340
1.32
5.57
6.3
6.1
0.2
0.2
e9/l
0.08
541
4712
1144
10842
1.61
5.56
14.9
12.5
—
—
—
0
0
601
5152
1.32
5.48
6.1
5.8
0.6
0.6
e9/l
0.05
518
4456
417
3393
1.34
5.47
3.2
3.4
2.4
2.4
mmol/l
0.03
356
2996
997
9216
1.40
5.34
5.8
5.4
39.1
39.4
mmol/mol
0.39
932
8610
601
5176
1.31
5.20
6.1
5.8
0.0
0.0
e9/l
0.02
517
4482
836
7540
1.32
5.13
4.4
4.0
11.1
11.6
mm/h
0.47
780
6998
588
5091
1.29
4.73
4.0
3.5
0.0
0.0
estimate
0.28
110
937
80
481
1.71
4.72
8.6
10.4
—
—
—
0
0
23
86
2.71
4.60
1.2
1.2
35.8
41.2
mg/l
0.26
18
70
310
2471
1.34
4.54
1.4
1.3
0.9
1.7
u/ml
2.17
92
667
426
3573
1.29
4.28
3.9
3.6
41.6
88.5
e6/l
2.04
298
2484
481
4101
1.28
4.23
2.2
2.1
—
—
—
0
0
593
5194
1.27
4.17
5.3
6.1
11.5
11.5
umol/l
0.00
559
4923
147
1051
1.45
4.11
7.8
7.8
5.1
5.1
kpa
0.04
140
1009
147
1052
1.45
4.09
7.8
7.8
12.9
12.3
kpa
0.65
141
1012
575
5025
1.27
4.09
3.9
3.5
0.0
0.0
estimate
0.00
115
953
323
2625
1.31
4.08
4.4
4.1
—
—
—
0
0
114
779
1.51
4.00
2.5
2.9
10.7
10.5
g/l
0.18
106
719
575
5037
1.26
3.97
5.2
4.8
0.0
0.0
estimate
0.50
112
975
109
739
1.52
3.97
4.0
3.8
73.2
81.7
ng/l
0.56
92
663
368
3056
1.29
3.93
3.4
3.2
7.5
7.6
mmol/l
0.31
323
2581
1037
9775
1.35
3.91
4.7
4.3
5.8
5.9
mmol/l
0.48
964
8964
668
5962
1.26
3.90
9.4
8.8
4.0
4.1
e9/l
0.28
583
5226
329
2695
1.30
3.90
3.5
3.0
—
—
—
0
0
362
3015
1.28
3.76
3.4
3.2
43.4
90.9
e6/l
0.94
281
2309
40
209
1.94
3.75
3.3
2.0
—
—
—
0
0
549
4809
1.25
3.72
4.0
4.0
—
—
—
0
0
429
3666
1.26
3.57
3.7
3.5
28.9
47.4
ng/l
0.88
290
2415
7
9
7.81
3.56
2.6
2.2
—
—
—
0
0
49
282
1.77
3.44
1.9
2.4
11.5
11.9
mg/l
0.12
42
256
179
1369
1.36
3.40
1.2
1.2
—
—
—
0
0
142
1049
1.40
3.34
8.1
7.9
0.5
1.2
mmol/l
1.45
112
831
242
1943
1.30
3.29
3.0
2.7
561.7
550.7
mosm/kgh2o
0.29
202
1664
54
324
1.70
3.29
1.6
1.4
10.9
9.9
u/l
0.14
45
258
379
3219
1.25
3.28
2.4
2.3
—
—
—
0
0
353
2976
1.26
3.25
3.6
2.9
—
—
—
0
0
763
6988
1.23
3.25
4.0
3.6
—
—
—
0
0
18
72
2.52
3.22
1.2
1.2
—
—
—
0
0
66
420
1.60
3.21
1.8
1.5
363.4
294.0
mu/l
0.71
59
373
101
707
1.47
3.19
2.7
3.0
4.3
4.1
e9/l
0.26
79
568
1068
10181
1.33
3.18
4.8
4.6
2.7
2.8
mmol/l
1.47
994
9449
281
2311
1.28
3.17
3.9
3.5
—
—
—
0
0
59
367
1.64
3.15
3.1
1.7
—
—
—
0
0
314
2625
1.26
3.09
6.7
6.6
—
—
—
0
0
304
2533
1.26
3.08
2.3
2.2
2.8
3.0
mg/l
0.44
253
2175
1052
10019
1.31
3.07
4.3
4.2
4.6
4.7
mmol/l
1.62
982
9353
12
40
3.02
2.97
8.3
16.0
—
—
—
0
0
1135
10940
1.39
2.97
11.3
9.9
26.0
26.2
u/l
0.14
1100
10598
202
1605
1.31
2.96
2.7
2.9
2.9
2.6
e6/l
0.14
105
866
10
30
3.35
2.91
1.0
1.7
—
—
—
0
0
104
747
1.43
2.89
1.3
1.2
174.2
153.2
iu/ml
0.21
47
302
295
2471
1.25
2.84
2.7
2.6
2366.8
6011.8
umol/l
1.43
258
2160
1010
9600
1.27
2.78
3.8
3.8
1.3
1.3
mmol/l
0.02
931
8871
124
925
1.38
2.78
2.2
2.4
26.8
36.0
u/l
2.56
99
785
31
166
1.89
2.78
1.3
1.6
0.6
0.9
g/l
1.27
24
128
225
1839
1.27
2.66
3.8
3.7
259.9
359.7
ng/l
0.34
172
1380
167
1313
1.31
2.65
2.0
2.4
194.4
119.9
ug/g
0.66
131
1034
275
2306
1.25
2.61
1.6
1.5
20.5
20.9
nmol/l
0.18
238
1973
1042
9961
1.27
2.60
4.3
4.1
1.4
1.5
mmol/l
1.68
965
9245
176
1398
1.30
2.60
2.3
2.3
2.4
2.3
g/l
0.75
167
1301
250
2076
1.25
2.58
1.7
1.7
460.4
30778459.9
pmol/l
2.17
212
1748
323
2760
1.23
2.57
3.5
3.1
0.4
0.4
e6/l
0.22
242
2072
51
324
1.60
2.55
4.6
2.3
—
—
—
0
0
5
7
7.17
2.55
1.2
1.3
78.6
98.3
umol/l
—
5
7
1187
11568
1.47
2.54
23.6
19.6
251.6
252.6
e9/l
0.23
1174
11295
247
2055
1.25
2.51
3.1
2.5
4.9
6.4
e6/l
0.98
222
1812
172
1369
1.30
2.50
1.4
1.3
429.3
478.6
titre
0.19
30
280
60
400
1.53
2.45
1.8
2.5
20.8
21.1
s
0.33
47
360
256
2144
1.24
2.45
1.5
1.4
2.1
2.3
g/l
1.45
164
1302
106
788
1.38
2.45
3.5
3.6
1.2
1.2
mmol/l
0.13
96
690
1187
11577
1.45
2.43
23.5
19.5
30.3
30.2
pg
0.62
1178
11424
1187
11577
1.45
2.43
23.6
19.5
90.8
90.7
fl
0.58
1178
11426
1187
11578
1.45
2.42
23.6
19.6
4.5
4.5
e12/l
0.15
1169
11273
77
543
1.45
2.40
1.4
1.4
25.0
27.2
iu/l
0.22
63
454
1187
11581
1.45
2.38
23.6
19.6
6.7
6.7
e9/l
0.07
1171
11271
1187
11582
1.45
2.37
23.8
19.7
135.7
135.4
g/l
0.36
1178
11426
360
3134
1.21
2.36
2.5
2.5
57.8
56.2
u/l
0.27
336
2904
12
47
2.57
2.27
4.1
1.4
—
—
—
0
0
119
917
1.33
2.20
4.1
4.2
—
—
—
0
0
92
682
1.38
2.19
3.5
3.8
7.4
7.4
ph
0.13
11
82
8
24
3.35
2.18
1.0
1.0
6.4
7.3
mg/g
—
8
24
186
1524
1.26
2.16
2.3
2.4
13.1
13.2
umol/l
0.01
177
1412
46
691
0.65
2.16
1.2
1.4
—
—
—
0
0
107
815
1.34
2.15
8.4
9.0
—
—
—
0
0
8
25
3.21
2.09
1.0
1.0
—
—
—
0
0
94
707
1.36
2.05
2.7
2.2
12.4
12.6
nmol/l
0.11
84
630
1006
9645
1.22
2.05
17.7
14.3
39.9
39.9
%
0.00
730
7197
92
690
1.36
2.05
3.5
3.8
5.4
5.1
kpa
1.28
87
652
515
4681
1.17
2.00
3.0
2.8
101.6
111.8
ug/l
0.76
479
4358
44
288
1.55
2.00
3.1
3.4
—
—
—
0
0
307
2673
1.20
1.98
4.5
3.8
0.0
0.0
estimate
1.28
111
941
96
729
1.34
1.98
2.2
3.0
65.6
66.7
g/l
0.75
89
673
148
1194
1.27
1.97
2.1
1.6
—
—
—
0
0
11
45
2.46
1.93
6.4
2.8
—
—
—
0
0
282
2444
1.20
1.91
2.3
2.2
—
—
—
0
0
107
831
1.31
1.90
1.4
1.5
—
—
—
0
0
111
867
1.31
1.90
1.2
1.2
—
—
—
0
0
7
22
3.19
1.88
1.0
1.1
—
—
—
0
0
7
22
3.19
1.88
1.0
1.1
—
—
—
0
0
7
22
3.19
1.88
1.0
1.1
—
—
—
0
0
504
4591
1.16
1.87
10.5
9.1
0.0
0.0
e9/l
0.34
420
3756
78
584
1.36
1.78
9.8
9.9
1.5
1.4
%
0.25
78
579
209
1777
1.21
1.74
1.3
1.3
18.3
33.8
iu/ml
2.83
65
544
7
24
2.93
1.72
1.1
1.0
—
—
—
0
0
156
1290
1.24
1.70
2.4
2.4
22.1
23.0
%
0.35
134
1107
65
477
1.38
1.69
2.7
2.4
—
—
—
0
0
172
1438
1.23
1.69
2.1
2.0
—
—
—
0
0
77
583
1.34
1.66
9.9
10.0
0.8
0.7
%
0.44
77
578
44
302
1.47
1.65
1.5
1.4
260.4
295.5
ug/g
0.43
24
178
68
508
1.36
1.60
3.8
4.1
—
—
—
0
0
264
2314
1.18
1.57
1.8
1.8
1.3
1.2
mg/l
0.04
202
1755
11
50
2.21
1.57
6.4
2.7
—
—
—
0
0
60
441
1.38
1.57
3.1
1.8
—
—
—
0
0
313
2783
1.17
1.56
3.7
3.7
—
—
—
0
0
18
309
0.58
1.54
7.6
10.2
—
—
—
0
0
64
477
1.36
1.54
2.6
1.8
—
—
—
0
0
10
44
2.28
1.53
1.8
3.3
493.0
780.5
u/ml
—
10
44
64
479
1.35
1.50
3.1
1.8
—
—
—
0
0
26
162
1.62
1.50
1.1
1.2
—
—
—
0
0
254
2228
1.18
1.50
4.5
3.8
1.0
1.0
kg/l
1.57
41
313
32
210
1.54
1.49
3.4
3.5
55.7
57.2
%
0.32
32
210
31
202
1.55
1.49
3.5
3.1
3.5
4.3
e9/l
1.91
31
202
94
745
1.28
1.48
5.8
4.3
0.1
0.6
%
0.49
20
189
63
473
1.35
1.46
2.6
1.8
—
—
—
0
0
103
829
1.26
1.44
5.5
4.2
0.7
0.9
%
0.54
28
238
63
474
1.35
1.44
3.0
1.8
—
—
—
0
0
308
2752
1.16
1.44
3.4
3.2
253.9
259.8
mg/l
0.01
199
1741
15
81
1.86
1.40
2.3
2.6
649.5
706.1
e6/l
—
6
32
208
1805
1.18
1.40
3.1
2.9
2.4
2.4
mmol/l
0.74
177
1583
139
1163
1.22
1.38
2.3
2.9
8.0
8.0
umol/l
0.00
119
1009
18
104
1.74
1.37
1.1
1.1
—
—
—
0
0
911
8763
1.14
1.35
20.2
16.1
13.6
13.6
%
0.04
897
8571
127
1060
1.22
1.30
2.5
2.7
1.8
1.8
%
0.00
111
954
93
755
1.25
1.24
5.7
4.1
0.5
0.5
%
0.01
19
183
320
2897
1.14
1.23
4.1
4.0
10.0
8.6
mg/mmol
0.14
203
1813
11
56
1.97
1.22
2.1
2.1
1.8
3.7
ug/l
1.70
11
48
19
116
1.65
1.21
1.5
1.5
—
—
—
0
0
88
1079
0.80
1.21
1.3
1.3
—
—
—
0
0
294
2655
1.14
1.18
1.7
1.7
1.4
1.4
mmol/l
0.27
264
2256
21
133
1.59
1.17
2.3
2.7
—
—
—
0
0
139
1185
1.19
1.17
1.5
1.4
—
—
—
0
0
26
174
1.50
1.16
1.5
1.4
97.0
63.7
mmol/l
1.86
20
143
5
20
2.51
1.15
1.8
1.4
—
—
—
0
0
305
2768
1.13
1.13
4.7
4.9
2.0
2.5
ug/l
1.35
275
2482
10
51
1.97
1.11
1.2
3.3
—
—
—
0
0
191
1680
1.16
1.11
1.3
1.2
10.6
13.4
u/ml
0.24
76
649
76
612
1.26
1.11
2.4
2.5
—
—
—
0
0
5
21
2.39
1.09
1.0
2.1
—
—
—
0
0
27
185
1.47
1.09
1.5
1.8
—
—
—
0
0
30
210
1.44
1.09
1.2
1.5
—
—
—
0
0
95
787
1.22
1.08
5.8
4.3
0.0
0.1
%
5.64
22
218
7
32
2.19
1.08
1.0
1.0
—
—
—
0
0
49
374
1.32
1.07
1.3
1.3
132.6
229.6
miu/ml
1.14
16
179
22
145
1.53
1.06
1.7
1.7
—
—
—
0
0
10
52
1.93
1.06
1.3
1.3
—
—
—
0
0
14
82
1.72
1.05
1.1
1.2
—
—
—
0
0
75
611
1.24
1.01
5.0
4.6
—
—
—
0
0
100
841
1.21
0.99
5.3
7.4
8.5
9.0
mmol/l
0.37
93
802
14
84
1.67
0.98
1.1
1.1
—
186.2
—
0
13
14
222
0.63
0.95
1.1
1.2
—
—
—
0
0
148
1295
1.16
0.94
1.6
1.6
—
—
—
0
0
16
101
1.59
0.93
1.4
1.3
7.9
7.2
g/l
0.24
11
75
16
101
1.59
0.93
1.4
1.3
0.6
0.4
g/l
0.80
11
74
16
101
1.59
0.93
1.4
1.3
4.2
2.8
g/l
0.97
11
73
25
175
1.44
0.93
2.0
2.7
—
—
—
0
0
10
55
1.82
0.92
1.5
3.1
—
—
—
0
0
93
787
1.20
0.89
2.7
2.7
72.3
71.0
e9/l
0.12
74
601
36
272
1.33
0.88
3.3
3.8
26.8
31.3
mg/l
0.55
29
216
36
272
1.33
0.88
3.3
3.8
43.6
73.6
mg/l
0.61
29
215
16
103
1.56
0.87
1.4
1.3
—
—
—
0
0
23
161
1.44
0.87
3.7
5.3
419.8
365.0
umol/l
0.75
18
144
30
221
1.37
0.86
1.1
1.2
0.2
3.1
u/ml
2.41
13
100
28
204
1.38
0.85
3.9
4.0
—
—
—
0
0
287
2641
1.11
0.85
2.7
3.0
1359.8
1225.4
ng/l
0.19
241
2239
305
2817
1.11
0.84
3.5
3.2
—
—
—
0
0
196
1768
1.13
0.82
1.6
1.6
—
—
—
0
0
25
180
1.40
0.82
1.2
1.3
4.6
6.1
u/ml
—
7
77
20
138
1.46
0.82
1.6
1.7
—
—
—
0
0
6
32
1.88
0.82
1.0
1.4
—
—
—
0
0
8
47
1.71
0.80
1.3
1.1
—
—
—
0
0
39
304
1.29
0.79
1.2
1.2
—
—
—
0
0
29
218
1.34
0.75
2.3
2.2
130.3
131.4
g/l
0.10
19
169
17
116
1.47
0.74
1.5
1.6
63.5
57.6
%
0.24
11
81
16
108
1.49
0.73
1.2
1.1
—
—
—
0
0
52
425
1.23
0.73
1.2
1.2
—
—
—
0
0
7
39
1.80
0.72
29.3
31.9
96.4
131.1
ug/l
—
7
31
20
143
1.41
0.70
4.9
3.3
0.9
1.2
%
0.29
14
123
7
41
1.71
0.70
1.0
1.0
—
—
—
0
0
55
455
1.22
0.70
2.1
2.2
3969.9
4865.9
u/l
0.17
21
188
10
61
1.64
0.68
1.1
1.0
—
—
—
0
0
38
473
0.80
0.67
3.1
3.5
—
—
—
0
0
20
272
0.73
0.67
1.6
1.4
—
—
—
0
0
124
1103
1.14
0.67
1.2
1.3
—
—
—
0
0
16
111
1.45
0.66
1.3
1.2
—
—
—
0
0
11
70
1.58
0.65
2.8
2.8
0.2
0.2
e9/l
0.48
11
62
76
654
1.17
0.64
1.2
1.2
—
—
—
0
0
176
1606
1.11
0.63
2.9
2.9
0.7
0.7
ug/l
0.54
124
1036
41
333
1.24
0.63
1.1
1.2
—
—
—
0
0
8
50
1.60
0.61
1.0
1.4
112.4
154.2
nmol/l
—
8
50
21
156
1.35
0.61
1.0
1.1
2.4
4.1
u/ml
—
10
53
26
200
1.31
0.61
3.0
2.3
15.8
16.2
%
0.25
14
112
11
163
0.67
0.60
1.3
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
2.7
—
0
21
20
266
0.75
0.60
1.5
1.4
—
—
—
0
0
8
52
1.54
0.59
1.5
1.7
—
55.2
—
0
8
32
257
1.25
0.55
1.1
1.1
—
—
—
0
0
47
394
1.20
0.55
1.8
2.1
1.3
1.5
g/l
0.57
39
356
87
768
1.14
0.55
2.4
3.0
160.5
179.9
ng/l
0.21
79
706
18
133
1.36
0.55
1.7
1.4
—
—
—
0
0
89
788
1.14
0.54
2.0
2.4
10.5
7.2
ug/l
0.35
67
698
25
195
1.29
0.54
1.2
1.5
102.2
105.2
u/ml
—
5
37
12
82
1.47
0.54
1.2
1.1
—
—
—
0
0
140
1277
1.11
0.53
1.3
1.3
—
—
—
0
0
70
611
1.15
0.52
1.7
1.7
—
—
—
0
0
9
63
1.43
0.52
1.1
1.0
—
—
—
0
0
6
98
0.61
0.52
1.2
1.2
—
—
—
0
0
33
270
1.23
0.50
1.7
2.6
36.5
37.9
g/l
0.60
28
234
77
680
1.14
0.50
1.5
1.3
302.5
218.5
u/ml
0.23
70
628
25
198
1.27
0.49
1.1
1.1
3.1
5.5
u/ml
0.53
12
108
60
521
1.16
0.49
3.8
5.0
23.8
24.2
mmol/l
0.42
53
476
16
119
1.35
0.48
2.7
1.9
31.1
32.5
pg
0.46
16
119
229
2149
1.08
0.48
1.9
1.9
—
—
—
0
0
41
346
1.19
0.47
3.4
3.9
1.4
1.4
mmol/l
0.01
41
339
24
191
1.26
0.46
1.1
1.1
3.6
3.8
u/ml
—
6
43
5
84
0.59
0.45
2.0
1.4
—
—
—
0
0
128
1174
1.10
0.45
23.1
23.7
1.2
1.3
inr
0.26
13
158
21
264
0.79
0.45
1.5
1.4
—
—
—
0
0
17
130
1.31
0.44
1.4
3.3
—
—
—
0
0
18
139
1.30
0.43
1.0
1.1
3.5
6.5
u/ml
—
10
52
26
212
1.23
0.42
1.2
1.2
—
—
—
0
0
12
87
1.38
0.42
7.4
3.3
58.7
53.7
%
—
7
68
19
149
1.28
0.42
1.4
1.5
—
—
—
0
0
13
96
1.36
0.41
1.2
1.1
—
—
—
0
0
12
161
0.74
0.41
1.0
1.2
—
—
—
0
0
59
521
1.14
0.40
2.4
2.8
65.4
52.7
u/ml
0.13
59
501
26
214
1.22
0.39
4.0
3.4
—
—
—
0
0
13
97
1.34
0.39
2.9
2.6
1.3
1.1
e9/l
—
7
56
5
35
1.43
0.39
1.0
1.0
—
4.2
—
0
5
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
102
934
1.10
0.39
3.5
4.3
1.3
1.9
mmol/l
0.99
83
737
15
115
1.31
0.39
1.1
1.3
—
—
—
0
0
11
80
1.38
0.38
1.5
1.3
—
—
—
0
0
30
252
1.20
0.38
1.1
1.3
—
—
—
0
0
245
2328
1.07
0.38
5.0
4.2
—
—
—
0
0
102
936
1.10
0.37
3.0
4.3
5.3
23.6
ug/l
1.29
81
768
14
107
1.31
0.37
1.3
1.4
—
—
—
0
0
5
37
1.35
0.37
1.6
1.4
—
1.2
%
—
0
8
30
254
1.19
0.35
1.8
1.3
—
—
—
0
0
6
42
1.43
0.35
1.0
1.5
—
—
—
0
0
6
42
1.43
0.35
1.5
1.3
—
—
—
0
0
20
241
0.83
0.32
3.1
4.7
—
—
—
0
0
14
110
1.28
0.31
7.9
4.2
—
—
—
0
0
52
466
1.12
0.31
1.1
1.1
—
—
—
0
0
7
53
1.32
0.31
1.6
2.9
1488.6
2047.1
ml
—
7
48
361
3729
0.96
0.30
2.5
2.6
—
—
—
0
0
79
727
1.09
0.29
1.4
1.4
—
—
—
0
0
71
650
1.10
0.29
4.2
2.9
—
—
—
0
0
10
76
1.32
0.28
1.0
1.6
0.9
1.0
g/l
—
10
76
15
122
1.23
0.27
1.1
1.3
—
54.0
—
0
7
12
96
1.25
0.24
1.6
1.3
61840.0
206473.1
e6/l
—
5
63
22
189
1.17
0.24
2.8
2.3
—
—
—
0
0
10
78
1.28
0.24
1.4
1.2
—
—
—
0
0
6
84
0.71
0.24
1.0
1.4
—
—
—
0
0
15
124
1.21
0.24
1.1
1.3
—
0.5
nmol/l
—
0
10
26
227
1.15
0.24
1.4
3.3
26.8
34.5
umol/l
2.24
21
190
112
1185
0.94
0.23
1.4
1.4
—
—
—
0
0
19
222
0.85
0.23
2.3
2.1
—
—
—
0
0
49
447
1.10
0.23
2.8
3.1
25.5
25.3
mmol/l
0.25
49
426
15
179
0.84
0.23
1.1
1.6
—
—
—
0
0
12
97
1.24
0.23
1.7
1.3
955.6
1657.9
e6/l
—
7
63
11
88
1.25
0.22
1.7
1.3
143210.2
44011.1
e6/l
—
5
48
7
91
0.77
0.22
2.0
1.6
—
—
—
0
0
5
40
1.25
0.22
1.2
1.4
—
—
—
0
0
18
153
1.18
0.22
1.4
1.4
—
—
—
0
0
98
924
1.07
0.22
1.8
2.4
0.2
0.2
g/l
0.02
91
871
22
191
1.15
0.22
1.1
1.1
0.5
0.7
u/ml
—
10
90
306
2974
1.04
0.21
1.5
1.5
—
—
—
0
0
13
156
0.83
0.21
2.0
1.2
16.4
36.3
u/l
0.94
13
137
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
12
145
0.83
0.21
2.0
2.1
13.3
13.2
%
0.11
12
145
0
13
0.00
0.21
0.0
1.1
—
267.1
—
0
8
0
13
0.00
0.21
0.0
5.0
—
—
—
0
0
85
800
1.07
0.20
4.4
3.4
—
—
—
0
0
10
80
1.25
0.20
1.6
2.2
—
1.7
—
0
8
0
14
0.00
0.20
0.0
3.1
—
—
—
0
0
0
14
0.00
0.20
0.0
3.5
—
—
—
0
0
25
221
1.13
0.20
1.3
1.2
222.5
261.9
u/ml
—
10
130
9
112
0.80
0.20
1.2
1.3
—
—
nmol/l
—
0
0
6
49
1.23
0.20
1.0
1.4
—
—
—
0
0
6
49
1.23
0.20
1.3
1.3
22.4
28.9
nmol/l
—
6
39
40
365
1.10
0.20
3.9
3.9
0.2
0.3
g/l
0.31
20
162
15
127
1.18
0.19
2.5
2.3
—
—
—
0
0
6
51
1.18
0.19
1.0
1.0
143.0
180.6
iu/ml
—
6
51
37
405
0.91
0.19
1.0
1.1
—
—
—
0
0
6
53
1.13
0.18
1.0
1.6
—
—
—
0
0
92
873
1.06
0.18
4.4
3.6
—
—
—
0
0
11
91
1.21
0.17
1.0
1.1
—
—
—
0
0
40
368
1.09
0.17
4.4
4.6
—
—
—
0
0
20
176
1.14
0.17
1.5
1.6
—
—
—
0
0
15
129
1.16
0.17
1.0
1.0
0.0
0.7
u/ml
—
5
33
40
433
0.92
0.16
1.8
1.8
—
—
—
0
0
9
79
1.14
0.15
1.0
1.1
—
—
—
0
0
12
102
1.18
0.15
1.4
1.4
—
34.8
—
0
5
11
94
1.17
0.13
4.2
3.7
—
—
—
0
0
10
117
0.85
0.13
2.0
2.6
—
—
—
0
0
12
104
1.16
0.12
4.6
2.7
—
—
—
0
0
81
843
0.96
0.12
1.4
1.4
—
—
—
0
0
25
230
1.09
0.11
2.5
2.5
10.2
123.8
ug/min
3.93
12
139
5
44
1.14
0.10
2.2
2.3
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
2043.2
1691.5
miu/ml
—
5
44
60
575
1.05
0.10
1.3
1.3
—
—
—
0
0
5
47
1.06
0.09
1.0
1.3
—
—
—
0
0
19
174
1.09
0.09
1.1
1.1
—
—
—
0
0
99
1019
0.97
0.09
1.4
1.4
—
—
—
0
0
36
380
0.95
0.09
1.2
1.3
—
—
—
0
0
35
331
1.06
0.09
1.4
1.5
1.2
1.2
g/l
0.17
35
312
12
107
1.12
0.08
1.8
2.2
—
—
—
0
0
23
214
1.08
0.08
5.0
4.0
2.4
2.4
mmol/l
0.01
17
144
6
58
1.03
0.08
1.0
1.1
—
—
—
0
0
16
146
1.10
0.08
2.4
2.8
7.2
9.1
umol/l
—
9
105
11
123
0.89
0.08
1.2
1.7
—
—
—
0
0
11
123
0.89
0.08
1.2
1.7
—
—
—
0
0
11
123
0.89
0.08
1.2
1.7
—
—
—
0
0
11
123
0.89
0.08
1.2
1.7
—
—
—
0
0
7
66
1.06
0.08
2.9
3.9
—
—
—
0
0
6
71
0.84
0.07
1.2
1.5
—
1908.4
—
0
13
6
75
0.80
0.07
1.0
1.0
—
—
—
0
0
8
75
1.07
0.07
1.3
1.1
—
—
—
0
0
24
225
1.07
0.07
2.8
3.6
22.5
27.3
mg/l
0.28
13
145
8
78
1.03
0.07
1.1
1.1
—
72.0
—
0
5
10
112
0.89
0.07
1.2
1.3
—
—
—
0
0
7
83
0.84
0.07
1.6
2.1
—
—
—
0
0
37
355
1.04
0.06
2.5
2.8
—
—
—
0
0
37
355
1.04
0.06
3.8
3.4
3242.0
3911.0
u/ml
0.06
32
310
122
1198
1.02
0.06
1.8
1.7
—
—
—
0
0
10
90
1.11
0.05
1.2
1.4
2.0
1.4
nmol/l
—
10
80
27
258
1.05
0.04
4.4
3.8
7.4
7.4
ph
1.24
22
211
18
170
1.06
0.04
1.4
1.2
—
—
—
0
0
11
119
0.92
0.04
1.9
2.6
106.2
105.6
mmol/l
0.22
11
119
11
119
0.92
0.04
1.9
2.6
4.0
4.0
mmol/l
0.16
11
119
38
369
1.03
0.03
2.0
1.8
2.6
2.0
ug/l
0.10
27
330
17
161
1.06
0.03
1.2
1.1
50.3
106.4
iu/ml
—
5
40
15
142
1.06
0.02
1.7
2.5
4.4
33.0
u/ml
0.51
15
132
120
1188
1.01
0.02
1.5
1.7
—
—
—
0
0
16
167
0.96
0.01
1.4
1.4
—
—
—
0
0
19
194
0.98
0.00
1.1
1.1
—
—
—
0
0
38
384
0.99
0.00
1.7
1.6
—
—
—
0
0
19
192
0.99
0.00
1.1
1.1
—
—
—
0
0
12
121
0.99
0.00
2.3
2.6
—
—
—
0
0
17
167
1.02
0.00
1.1
1.1
—
—
—
0
0
24
237
1.01
0.00
1.5
1.6
13295.5
12810.9
e6/l
0.03
17
174
22
215
1.02
0.00
3.8
4.4
—
—
—
0
0
12
125
0.96
0.00
1.0
1.2
—
—
—
0
0
5
54
0.93
0.00
1.0
1.2
90.8
466.3
u/l
—
5
49
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
170.8
—
0
9
7
72
0.97
0.00
1.3
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
12.1
—
0
8
0
6
0.00
0.00
0.0
4.7
—
—
—
0
0
8
87
0.92
0.00
1.6
2.4
—
—
—
0
0
6
66
0.91
0.00
1.2
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
3.9
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
5.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
0.00
1.6
1.4
—
—
—
0
0
26
260
1.00
0.00
2.8
2.5
24.8
24.9
mmol/l
0.03
21
229
0
5
0.00
0.00
0.0
1.2
—
0.0
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
35.4
—
0
7
0
6
0.00
0.00
0.0
1.5
—
326.8
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_VERTISTRAB and mortality.

Females

Parameter HR [95% CI] p-value
H7_VERTISTRAB 0.921 [0.77, 1.09] 0.349
Birth year 0.992 [0.98, 1.0] 0.078

During the follow-up period (1.1.1998 — 31.12.2019), 229 out of 3370 females with H7_VERTISTRAB died.

Males

Parameter HR [95% CI] p-value
H7_VERTISTRAB 1.046 [0.89, 1.23] 0.586
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 278 out of 2894 males with H7_VERTISTRAB died.

Mortality risk

Mortality risk for people of age

years, who have H7_VERTISTRAB.

N-year risk Females Males
1 0.086% 0.209%
5 0.507% 1.234%
10 1.248% 2.985%
15 2.428% 5.589%
20 4.468% 9.332%

Relationships between endpoints

Index endpoint: H7_VERTISTRAB – Vertical strabismus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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