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Vertical strabismus

DOID EFO Endpoint Browser PheWeb

H7_VERTISTRAB

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H50.2
  • Hospital discharge: ICD-9 — 3783
  • Hospital discharge: ICD-8 — 37302
  • Cause of death: ICD-10 — H50.2
  • Cause of death: ICD-9 — 3783
  • Cause of death: ICD-8 — 37302

2 out of 7 registries used, show all original rules.

1315

4. Check minimum number of events

None

1315

5. Include endpoints

None

1315

6. Filter based on genotype QC (FinnGen only)

1278

Control definitions (FinnGen only)

Control exclude
H7_OCUMUSCLE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H50
Name in latin
Strabismus verticalis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9645 5200 4422
Only index persons 8778 4806 3972
Unadjusted period prevalence (%)
Whole population 0.14 0.15 0.12
Only index persons 0.17 0.18 0.15
Median age at first event (years)
Whole population 28.68 28.55 28.72
Only index persons 30.56 30.52 30.61

-FinnGen-

Key figures

All Female Male
Number of individuals 1278 777 501
Unadjusted period prevalence (%) 0.26 0.28 0.23
Median age at first event (years) 48.41 44.22 54.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1315
Matched controls
13150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H50.2
ICD-10 Finland
Vertical strabismus
16384.0
307.7
1053
*
H53.2
ICD-10 Finland
Diplopia
32.7
307.7
306
121
CEC00
NOMESCO Finland
Recession of extraocular muscle
2229.6
214.6
202
*
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
190.3
178
*
H50.52
ICD-10 Finland
Exophoria
93.0
181.4
95
11
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
159.7
150
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
58.9
156.5
88
16
H50.1
ICD-10 Finland
Divergent concomitant strabismus
+∞
154.3
145
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
151.0
142
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.9
147.1
316
671
H50.0
ICD-10 Finland
Convergent concomitant strabismus
1561.4
145.6
139
*
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
126.1
119
*
3503
FHL
Single muscle retroposition
+∞
110.0
104
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
50.9
84.6
49
10
H50.31
ICD-10 Finland
Intermittent exotropia
849.5
82.4
80
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
81.1
77
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
76.8
73
*
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
7.7
75.0
109
152
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
28.8
74.2
50
18
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
73.6
70
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
73.1
360
1358
XCK00
NOMESCO Finland
Perimetry
5.0
63.8
146
318
H50.8
ICD-10 Finland
Other specified strabismus
+∞
58.8
56
*
H52.0
ICD-10 Finland
Hypermetropia
12.5
53.3
53
44
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
52.4
50
*
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
50.3
48
*
H50.9
ICD-10 Finland
Strabismus, unspecified
173.1
48.2
50
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
18.6
47.4
38
21
WX140
NOMESCO Finland
Parabulbar anesthesy
4.7
47.1
114
259
H52.1
ICD-10 Finland
Myopia
9.0
44.6
56
65
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
42.9
41
*
H52.2
ICD-10 Finland
Astigmatism
11.7
40.6
42
37
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
39.8
612
3782
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
38.7
37
*
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
37.7
36
*
H03BB01
ATC
carbimazole; oral
4.4
36.6
96
232
H50.4
ICD-10 Finland
Other and unspecified heterotropia
+∞
33.5
32
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
33.3
157
560
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
5.0
32.1
71
149
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.4
30.8
115
356
H50.50
ICD-10 Finland
Alternating hyperphoria
84.6
29.9
33
*
3780B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONVERGENS ALTERNANS]
+∞
29.3
28
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.0
29.2
465
2832
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
79.4
27.9
31
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.6
27.8
181
763
CE2W4
NOMESCO Finland
Eye movement mapping
54.6
27.3
32
6
3504
FHL
Retroposition of two muscles
+∞
26.1
25
*
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
26.1
25
*
F95
ICPC
Strabismus
265.6
25.8
26
*
CEC50
NOMESCO Finland
Advancement of extraocular muscle
+∞
25.1
24
*
AA1AD
NOMESCO Finland
CT of head and brain
2.0
24.5
363
2133
H50.51
ICD-10 Finland
Esophoria
+∞
24.0
23
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.2
23.6
63
154
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
30.7
22.8
30
10
CS494
NOMESCO Finland
Other visual field testing
4.7
22.6
53
117
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
22.5
365
2203
H05.2
ICD-10 Finland
Exophthalmic conditions
50.9
21.2
25
5
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
20.9
20
*
H062, E050,
ICD-10 Finland
42.4
20.5
25
6
ZXA00
NOMESCO Finland
Right side
1.9
20.2
357
2202
N07AA02
ATC
pyridostigmine; systemic
17.6
20.1
31
18
3780A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Convergent concomitant strabismus[STRABISMUS CONCOMITANS CONVERGENS]
+∞
19.8
19
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
19.8
19
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
202.9
19.6
20
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
19.6
179
873
Z3231
NOMESCO Finland
Registered nurse
1.8
19.3
371
2343
ZXA10
NOMESCO Finland
Bilateral
2.0
18.7
252
1418
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
18.7
141
633
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
17.8
138
627
G70.0
ICD-10 Finland
Myasthenia gravis
23.1
17.8
25
11
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
17.7
17
*
3501
FHL
Myotomy or tenotomy
+∞
17.7
17
*
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
6.2
17.7
30
49
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
17.0
101
405
ZXA05
NOMESCO Finland
Left side
1.8
16.9
320
2000
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
16.7
16
*
3505
FHL
Single muscle resection
+∞
16.7
16
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
16.4
175
903
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
4.5
16.2
39
88
108
Kela drug reimbursment
Myasthenia gravis
30.5
16.1
21
7
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
30.5
16.1
21
7
H02.4
ICD-10 Finland
Ptosis of eyelid
3.7
15.8
51
143
3507
FHL
Retroposition and resection
161.9
15.5
16
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
14.9
131
626
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.6
14.8
28
51
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
14.7
118
543
3781B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALTERNANS]
+∞
14.6
14
*
3781A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS CONCOMITANS DIVERGENS]
+∞
13.6
13
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.6
13.6
82
332
CAC30
NOMESCO Finland
Decompression of orbit to sinuses
141.4
13.5
14
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
13.3
102
461
WX402
NOMESCO Finland
General anaesthesia
1.7
13.1
276
1764
H26.4
ICD-10 Finland
After-cataract
2.2
12.8
117
569
H03AA01
ATC
levothyroxine sodium; systemic
1.7
12.7
297
1951
Z3229
NOMESCO Finland
Other healthcare associate professional
2.2
12.6
110
525
3782B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Intermittent heterotropia[STRABISMUS DIVERGENS INTERMITTENS]
+∞
12.5
12
*
3510
FHL
Cardiac surgery on three or more muscles
+∞
12.5
12
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
12.5
336
2288
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.7
12.2
39
109
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
12.2
144
770
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.0
12.1
53
181
R42
ICD-10 Finland
Dizziness and giddiness
1.7
12.0
278
1818
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
8.8
12.0
25
29
S06.2
ICD-10 Finland
Diffuse brain injury
5.8
11.5
21
37
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
11.5
11
*
BAA60
NOMESCO Finland
Total thyroidectomy
3.3
11.4
43
134
TAB00
NOMESCO Finland
Lumbar puncture
2.5
10.8
68
281
Z2445
NOMESCO Finland
Psychologist
2.6
10.8
62
245
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
10.7
435
3236
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.9
10.6
48
167
3508
FHL
Transposition or anteposition
+∞
10.4
10
*
CEC40
NOMESCO Finland
Resection and advancement of extraocular muscle
+∞
10.4
10
*
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
10.4
10
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
10.2
383
2795
WX002
NOMESCO Finland
Sedation and analgesia
1.7
10.2
235
1532
H53.3
ICD-10 Finland
Other disorders of binocular vision
9.2
10.0
20
22
XA800
NOMESCO Finland
Neuropsychological investigation
2.5
9.8
59
239
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
9.7
126
695
N99
ICPC
Neurological disease other
4.6
9.5
22
48
104
Kela drug reimbursment
Thyroid insufficiency
2.1
9.5
90
444
CAC20
NOMESCO Finland
Lateral decompression of orbit
100.7
9.4
10
*
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
9.4
9
*
3784B
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Heterophoria[EXOPHORIA]
+∞
9.4
9
*
CEC85
NOMESCO Finland
Combined correction of cyclodeviation
+∞
9.4
9
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.5
9.4
32
94
ZXD20
NOMESCO Finland
Day surgery
1.7
9.3
164
994
CAC44
NOMESCO Finland
Combined decompression of orbit
37.0
9.0
11
*
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
24.2
8.9
12
5
CA1AD
NOMESCO Finland
Orbita CT
24.2
8.9
12
5
R1250, ,
SPAT
3.6
8.8
29
83
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.8
8.8
43
157
WX400
NOMESCO Finland
Inhalation anesthesy
2.4
8.7
61
265
CAC10
NOMESCO Finland
Reconstruction of orbital wall using bone graft or plate
14.1
8.7
14
10
ZXE00
NOMESCO Finland
One hour or less
1.4
8.6
467
3643
H50.39
ICD-10 Finland
Intermittent heterotropia
90.6
8.4
9
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
8.4
188
1212
CEE00
NOMESCO Finland
Posterior fixation suture of extraocular muscle
+∞
8.3
8
*
H50.59
ICD-10 Finland
Heterophor UNS
+∞
8.3
8
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.1
8.3
33
107
A02BC05
ATC
esomeprazole; systemic
1.4
8.2
470
3692
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
7.6
8.2
18
24
WX725
NOMESCO Finland
Noninvasive ventilation
2.2
8.2
71
339
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.1
8.1
77
380
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
4.1
8.1
22
55
T90.5
ICD-10 Finland
Sequelae of intracranial injury
4.1
8.1
22
55
N06AX11
ATC
mirtazapine; oral
1.4
8.0
399
3058
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
4.3
8.0
20
47
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
7.8
7.9
17
22
S02.30
ICD-10 Finland
Fracture of orbital floor, closed
6.0
7.7
20
34
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
7.6
88
467
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.5
877
7730
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.5
441
3470
N28
ICPC
Limited function/disability (N)
3.7
7.5
23
63
H49.9
ICD-10 Finland
Paralytic strabismus, unspecified
+∞
7.3
7
*
H50
ICD-10 Finland
Other strabismus
+∞
7.3
7
*
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
3.9
7.3
21
55
S01EE01
ATC
latanoprost; ophthalmic
2.1
7.2
67
328
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
7.2
322
2410
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
7.2
268
1937
A04
ICPC
Weakness/tiredness general
1.6
7.1
175
1156
R51.80
ICD-10 Finland
Headache
1.6
6.9
189
1276
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
4.0
6.9
19
48
S06.0
ICD-10 Finland
Concussion
1.7
6.9
136
849
Z01.2
ICD-10 Finland
Dental examination
1.4
6.8
540
4444
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
11.0
6.8
12
11
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.8
483
3911
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.8
6.7
104
607
SPAT1360
SPAT
Extensive global examination
1.9
6.6
78
418
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
6.6
244
1759
XCW11
NOMESCO Finland
Assessment of strabismus
70.2
6.4
7
*
N05CF01
ATC
zopiclone; oral
1.4
6.4
354
2744
S06.3
ICD-10 Finland
Focal brain injury
3.8
6.4
19
51
H53.4
ICD-10 Finland
Visual field defects
3.1
6.4
26
86
F80.1
ICD-10 Finland
Expressive language disorder
4.1
6.4
17
42
XKD00
NOMESCO Finland
Uroflowmetry
1.6
6.3
148
964
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
6.3
148
964
SPAT1229
SPAT
Assessment of need for aid
1.9
6.3
80
439
CED00
NOMESCO Finland
Plication of extraocular muscle
+∞
6.3
6
*
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
6.3
6
*
3781X
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Divergent concomitant strabismus[STRABISMUS DIVERGENS ALIUS]
+∞
6.3
6
*
CD2S4
NOMESCO Finland
Photography of eye
7.1
6.2
14
20
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
6.2
172
1165
A02BC02
ATC
pantoprazole; systemic
1.3
6.2
787
6918
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
6.2
588
4953
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.5
6.2
20
57
114
Kela drug reimbursment
Glaucoma
1.8
6.1
86
488
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
6.1
149
981
R01AD09
ATC
mometasone; nasal
1.3
6.1
537
4472
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.7
6.1
32
122
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
6.1
503
4151
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
6.1
252
1855
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
3.5
6.0
20
58

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
66
60
11.53
62.77
1.2
1.1
3.71
1.81
nmol/l
0.35
16
12
115
286
4.31
42.29
3.5
1.8
6.47
4.70
iu/l
0.73
64
109
681
5120
1.68
18.79
6.8
6.7
1.21
1.21
mmol/l
0.38
578
4393
621
4639
1.64
16.94
6.0
6.0
1.21
1.21
mmol/l
0.42
572
4265
136
680
2.12
13.82
4.8
3.2
4.47
4.58
pmol/l
0.47
123
599
423
3023
1.59
12.92
2.3
2.1
225.62
222.07
u/l
0.03
404
2847
61
220
2.86
12.62
2.0
1.8
—
—
—
0
0
744
6114
1.50
11.45
4.9
4.7
6.51
6.65
mmol/l
1.13
704
5699
587
4661
1.47
10.33
13.1
14.2
1.24
1.24
inr
0.01
163
1391
1101
9989
1.63
9.56
6.3
4.7
1.82
2.00
mu/l
0.85
1024
9213
955
8403
1.50
9.47
5.7
4.0
14.83
14.70
pmol/l
0.84
884
7702
263
1815
1.56
8.89
1.7
1.7
1049.25
1188.39
nmol/l
1.82
194
1380
1168
10815
1.72
8.69
15.3
13.5
21.83
23.28
mg/l
0.72
945
8492
163
1006
1.71
8.62
2.2
2.1
353.96
376.44
nmol/l
0.80
147
927
1177
10938
1.72
8.42
17.6
15.2
139.74
139.63
mmol/l
0.89
1157
10657
1179
10964
1.73
8.38
17.8
15.3
3.96
3.96
mmol/l
0.00
1159
10669
399
3044
1.45
8.20
4.0
3.9
7.40
7.40
ph
0.97
80
583
550
4445
1.41
8.19
4.5
4.8
36.24
35.73
g/l
1.29
513
4145
523
4194
1.41
8.13
2.0
1.9
97.65
94.75
pmol/l
0.76
273
2177
918
8116
1.43
8.04
7.4
7.3
79.90
78.65
u/l
0.21
870
7652
35
122
2.92
7.78
2.5
2.2
—
—
—
0
0
634
5297
1.38
7.54
6.3
6.0
28.27
28.40
%
0.11
598
5000
33
114
2.94
7.47
2.4
1.9
—
—
—
0
0
55
247
2.28
7.35
2.0
1.7
19.21
35.74
e6/l
0.32
43
187
55
247
2.28
7.35
2.0
1.7
1046.60
937.58
e6/l
0.05
43
195
623
5223
1.37
7.09
5.9
5.8
57.02
56.81
%
0.17
587
4930
53
238
2.28
7.09
1.2
1.5
3.68
3.68
mmol/l
0.00
48
226
348
2667
1.41
6.76
4.0
3.9
88.53
90.87
%
1.00
340
2596
613
5155
1.35
6.71
6.5
6.2
8.54
8.47
%
0.24
579
4853
610
5126
1.35
6.71
6.2
5.9
2.80
2.83
%
0.13
574
4818
841
7431
1.37
6.64
5.1
4.1
—
—
—
0
0
224
1586
1.50
6.59
1.9
2.2
30.13
29.68
s
0.38
216
1540
806
7082
1.36
6.55
5.4
4.3
3292.29
2787.72
e6/l
0.07
14
102
653
5573
1.34
6.36
6.0
5.8
1.92
1.94
e9/l
0.19
568
4935
589
4952
1.34
6.34
6.3
5.9
0.69
0.66
%
0.61
554
4643
1199
11342
1.65
6.18
14.8
12.5
—
—
—
0
0
194
1351
1.51
6.17
5.0
5.7
1.05
1.05
mmol/l
0.02
180
1258
882
7897
1.35
6.11
4.4
4.0
11.00
11.66
mm/h
0.66
822
7335
228
1654
1.46
5.91
2.7
3.4
0.82
0.82
mmol/l
0.01
216
1562
1047
9660
1.41
5.85
5.8
5.4
39.14
39.42
mmol/mol
0.48
976
9025
650
5599
1.32
5.70
6.2
6.1
0.19
0.19
e9/l
0.09
566
4932
599
5107
1.32
5.63
6.6
6.2
—
—
—
0
0
630
5416
1.31
5.55
6.1
5.8
0.57
0.57
e9/l
0.03
543
4684
434
3558
1.33
5.31
3.2
3.4
2.35
2.35
mmol/l
0.22
376
3160
629
5429
1.30
5.29
6.0
5.8
0.04
0.04
e9/l
0.01
541
4695
119
770
1.60
5.25
3.8
3.8
74.07
82.74
ng/l
0.60
99
688
508
4286
1.30
4.97
2.1
2.1
—
—
—
0
0
583
5026
1.29
4.79
2.5
2.5
—
—
—
0
0
84
513
1.68
4.67
8.3
10.4
—
—
—
0
0
523
4467
1.28
4.55
2.5
2.3
76.44
76.26
nmol/l
0.05
468
4030
42
208
2.05
4.51
3.1
1.9
—
—
—
0
0
23
87
2.67
4.50
1.2
1.2
35.83
41.75
mg/l
0.29
18
71
322
2587
1.32
4.41
1.4
1.3
0.87
1.68
u/ml
2.18
97
690
1090
10251
1.37
4.41
4.7
4.3
5.85
5.89
mmol/l
0.46
1010
9404
611
5337
1.27
4.39
4.0
3.5
0.02
0.01
estimate
0.28
114
980
798
7200
1.28
4.38
3.3
3.1
46.07
45.59
u/l
0.06
755
6776
621
5451
1.26
4.22
5.3
6.1
11.53
11.60
umol/l
0.05
584
5177
403
3360
1.29
4.17
2.3
2.3
—
—
—
0
0
443
3748
1.27
4.05
3.8
3.6
40.67
88.91
e6/l
2.30
310
2618
699
6247
1.25
3.98
9.3
8.8
4.02
4.08
e9/l
0.24
608
5468
118
814
1.49
3.95
2.5
2.9
10.57
10.54
g/l
0.02
110
750
108
733
1.52
3.90
2.7
3.0
5.16
6.08
e9/l
0.29
85
612
336
2761
1.29
3.85
4.4
4.1
—
—
—
0
0
599
5277
1.25
3.82
3.9
3.5
0.00
0.00
estimate
0.50
123
1077
448
3829
1.26
3.70
3.8
3.5
28.56
49.00
ng/l
1.05
307
2523
152
1115
1.41
3.69
7.6
7.8
5.13
5.13
kpa
0.01
144
1070
152
1116
1.41
3.67
7.6
7.8
12.95
12.27
kpa
0.80
145
1073
383
3217
1.27
3.66
3.3
3.2
7.41
7.61
mmol/l
0.41
339
2736
1193
11462
1.44
3.62
11.3
9.9
25.95
26.12
u/l
0.12
1154
11110
597
5281
1.24
3.60
5.2
4.8
0.00
0.00
estimate
0.50
116
1020
1122
10677
1.35
3.57
4.8
4.6
2.72
2.77
mmol/l
1.03
1043
9922
377
3169
1.27
3.56
3.4
3.2
41.92
87.22
e6/l
0.95
294
2438
341
2832
1.28
3.56
3.4
3.0
—
—
—
0
0
7
9
7.81
3.56
2.6
2.2
—
—
—
0
0
1106
10506
1.33
3.54
4.4
4.2
4.60
4.67
mmol/l
1.31
1031
9815
61
372
1.67
3.48
3.0
1.7
—
—
—
0
0
50
290
1.75
3.41
1.9
2.3
11.51
11.81
mg/l
0.10
43
263
68
432
1.61
3.32
1.9
1.6
380.75
298.10
mu/l
0.86
61
384
33
170
1.97
3.26
1.3
1.7
0.55
0.87
g/l
1.56
26
131
13
43
3.04
3.25
7.7
15.0
—
—
—
0
0
799
7335
1.23
3.24
3.9
3.6
—
—
—
0
0
1062
10067
1.29
3.20
3.9
3.8
1.28
1.28
mmol/l
0.01
977
9297
292
2411
1.27
3.17
3.9
3.5
—
—
—
0
0
184
1429
1.33
3.15
1.2
1.2
—
—
—
0
0
18
73
2.49
3.13
1.7
1.6
—
—
—
0
0
14
50
2.82
3.09
3.6
1.5
—
—
—
0
0
55
338
1.65
3.08
1.6
1.4
10.81
9.85
u/l
0.15
46
267
1096
10446
1.30
3.06
4.3
4.2
1.44
1.47
mmol/l
1.67
1013
9704
486
4262
1.22
3.04
3.6
3.3
6.05
5.84
ph
0.91
43
343
147
1110
1.37
3.03
7.9
7.8
0.43
1.19
mmol/l
1.65
117
892
1245
12112
1.52
2.99
23.5
19.7
251.88
252.72
e9/l
0.17
1230
11829
11
31
3.57
2.99
1.0
1.7
—
—
—
0
0
328
2764
1.25
2.97
6.8
6.6
—
—
—
0
0
109
785
1.42
2.97
1.3
1.2
171.25
149.09
iu/ml
0.24
50
318
220
1768
1.29
2.95
2.6
2.7
0.77
1.03
e6/l
1.09
118
997
129
959
1.38
2.93
3.9
4.1
—
—
—
0
0
1244
12106
1.51
2.92
23.7
19.8
40.41
40.51
%
0.09
1169
11363
53
328
1.64
2.90
4.5
2.2
—
—
—
0
0
1245
12121
1.51
2.88
23.4
19.6
30.26
30.22
pg
0.39
1235
11963
1245
12121
1.51
2.88
23.5
19.6
90.77
90.68
fl
0.31
1235
11965
1245
12122
1.51
2.86
23.5
19.7
4.51
4.50
e12/l
0.39
1225
11803
1245
12122
1.51
2.86
23.5
19.7
6.72
6.70
e9/l
0.10
1227
11798
254
2088
1.27
2.84
3.0
2.8
557.40
542.26
mosm/kgh2o
0.47
216
1799
343
2920
1.24
2.82
3.8
3.7
—
—
—
0
0
182
1435
1.31
2.81
1.4
1.3
576.77
475.49
titre
0.24
31
293
372
3196
1.23
2.81
3.6
2.9
—
—
—
0
0
98
700
1.43
2.80
3.5
3.8
7.41
7.40
ph
0.13
11
82
1245
12127
1.50
2.80
23.7
19.8
135.74
135.28
g/l
0.58
1235
11967
209
1682
1.29
2.77
2.7
2.9
2.87
2.61
e6/l
0.11
109
914
5
6
8.36
2.75
1.2
1.3
78.60
97.50
umol/l
—
5
6
314
2656
1.24
2.73
2.3
2.2
2.89
2.96
mg/l
0.24
260
2269
98
708
1.42
2.65
3.5
3.8
5.34
5.13
kpa
1.21
93
685
302
2553
1.24
2.64
2.3
2.2
—
—
—
0
0
173
1369
1.30
2.61
2.1
2.4
193.28
121.56
ug/g
0.66
136
1084
129
982
1.35
2.55
2.2
2.4
27.06
36.00
u/l
2.64
103
834
115
861
1.37
2.53
1.4
1.5
—
—
—
0
0
10
31
3.24
2.52
1.1
1.4
63.70
86.71
nmol/24h
—
10
31
263
2201
1.24
2.51
1.7
1.7
455.20
26861271.66
pmol/l
1.98
223
1854
305
2595
1.23
2.50
2.7
2.6
2284.65
5705.62
umol/l
1.39
269
2283
79
555
1.45
2.49
1.4
1.4
25.59
26.72
iu/l
0.11
65
462
267
2241
1.24
2.49
1.5
1.5
2.16
2.34
g/l
1.22
170
1358
114
856
1.36
2.47
8.1
8.8
—
—
—
0
0
234
1940
1.25
2.43
3.7
3.7
268.26
365.79
ng/l
0.34
177
1458
336
2898
1.21
2.40
3.5
3.1
0.34
0.45
e6/l
0.36
255
2199
403
3541
1.20
2.37
3.2
3.2
29.48
32.62
u/l
1.66
384
3369
12
46
2.62
2.36
6.4
3.0
—
—
—
0
0
181
1463
1.28
2.33
2.3
2.3
2.42
2.34
g/l
0.92
172
1358
61
415
1.49
2.28
1.8
2.5
20.77
21.11
s
0.29
47
375
375
3284
1.20
2.27
2.5
2.4
57.18
83.28
u/l
0.54
348
3046
284
2426
1.22
2.23
1.6
1.5
20.31
20.95
nmol/l
0.31
246
2079
256
2167
1.23
2.20
3.0
2.5
4.99
6.43
e6/l
0.90
233
1956
109
832
1.34
2.15
3.4
3.6
1.23
1.23
mmol/l
0.07
98
722
73
524
1.42
2.09
3.7
4.0
—
—
—
0
0
8
25
3.21
2.09
1.0
1.0
6.36
7.28
mg/g
—
8
25
63
445
1.44
1.99
3.0
1.8
—
—
—
0
0
192
1594
1.24
1.98
2.3
2.4
13.09
13.19
umol/l
0.07
182
1486
97
738
1.34
1.97
2.6
2.2
12.10
12.47
nmol/l
0.18
87
661
221
1866
1.22
1.95
1.3
1.2
19.33
33.87
iu/ml
2.54
66
581
67
481
1.41
1.94
2.5
1.8
—
—
—
0
0
47
315
1.51
1.93
2.9
3.3
—
—
—
0
0
67
483
1.41
1.90
3.0
1.8
—
—
—
0
0
70
509
1.40
1.89
2.6
2.4
—
—
—
0
0
82
614
1.36
1.86
9.5
9.7
1.43
1.37
%
0.13
82
609
66
477
1.40
1.85
2.5
1.8
—
—
—
0
0
66
478
1.40
1.83
3.0
1.8
—
—
—
0
0
18
326
0.55
1.81
7.6
10.2
—
—
—
0
0
50
711
0.69
1.81
1.2
1.4
—
—
—
0
0
7
23
3.05
1.80
1.0
1.1
—
—
—
0
0
7
23
3.05
1.80
1.0
1.1
—
—
—
0
0
7
23
3.05
1.80
1.0
1.1
—
—
—
0
0
528
4833
1.15
1.79
10.5
9.1
0.00
0.00
e9/l
0.34
440
3947
319
2813
1.18
1.75
4.5
3.8
0.00
0.01
estimate
1.28
115
985
81
613
1.34
1.73
9.6
9.8
0.75
0.68
%
0.31
81
608
114
906
1.28
1.72
1.2
1.2
—
—
—
0
0
7
24
2.93
1.72
1.1
1.0
—
—
—
0
0
532
4884
1.15
1.71
3.0
2.8
101.23
111.83
ug/l
0.84
496
4537
163
1353
1.23
1.70
2.4
2.4
22.14
23.10
%
0.40
141
1159
317
2801
1.17
1.70
1.7
1.7
1.35
1.39
mmol/l
0.36
283
2376
276
2411
1.18
1.69
1.8
1.8
1.23
1.26
mg/l
0.04
212
1828
34
221
1.55
1.63
1.3
1.2
31.86
40.13
u/ml
—
7
20
98
772
1.29
1.60
2.2
3.0
65.64
66.66
g/l
0.68
91
711
23
137
1.69
1.56
2.3
2.8
—
—
—
0
0
266
2334
1.18
1.55
4.4
3.8
1.01
1.02
kg/l
1.45
43
335
13
64
2.04
1.54
2.3
2.0
1.62
3.38
ug/l
1.88
13
57
99
789
1.28
1.49
5.6
4.3
3.18
0.51
%
0.40
22
212
989
9523
1.16
1.48
19.5
16.0
14.77
14.76
%
0.02
977
9356
10
45
2.23
1.46
1.8
3.4
493.00
760.51
u/ml
—
10
45
150
1260
1.22
1.42
2.2
1.7
—
—
—
0
0
108
879
1.25
1.38
5.3
4.1
0.63
0.99
%
0.89
31
302
26
166
1.58
1.38
1.1
1.0
1.00
2.08
u/ml
—
10
72
18
104
1.74
1.37
1.1
1.1
—
—
—
0
0
5
17
2.95
1.36
1.4
1.1
—
—
—
0
0
177
1521
1.19
1.33
2.1
2.0
—
—
—
0
0
43
309
1.40
1.31
1.6
1.5
260.43
293.96
ug/g
0.40
24
180
132
1108
1.21
1.28
2.5
2.7
1.74
1.77
%
0.11
116
998
64
494
1.31
1.26
1.0
1.1
—
0.99
—
0
7
216
1899
1.16
1.24
3.1
2.9
2.43
2.45
mmol/l
1.22
185
1664
20
123
1.64
1.24
1.5
1.5
—
—
—
0
0
321
2906
1.14
1.23
3.3
3.2
244.26
267.30
mg/l
0.04
208
1859
32
221
1.46
1.22
3.4
3.5
55.72
57.43
%
0.39
32
221
31
213
1.47
1.21
3.5
3.1
3.47
4.26
e9/l
1.94
31
213
22
140
1.58
1.20
1.8
1.7
—
—
—
0
0
43
315
1.38
1.19
1.2
1.1
0.58
5.92
u/ml
—
6
39
156
1341
1.19
1.18
1.6
1.6
—
—
—
0
0
92
1119
0.81
1.18
1.3
1.3
—
—
—
0
0
202
1775
1.16
1.18
1.3
1.2
10.20
12.83
u/ml
0.23
80
680
27
182
1.49
1.16
1.5
1.4
97.24
62.99
mmol/l
2.09
21
150
306
2772
1.14
1.16
2.7
2.9
1319.42
1248.45
ng/l
0.10
255
2339
5
20
2.51
1.15
1.6
1.3
25.77
0.11
u/ml
—
5
20
97
801
1.23
1.13
5.5
4.0
0.56
0.61
%
0.08
25
261
15
88
1.71
1.11
1.1
1.1
—
176.43
—
0
14
17
104
1.64
1.09
1.4
1.4
3.98
2.76
g/l
0.79
12
76
17
104
1.64
1.09
1.4
1.4
7.55
7.16
g/l
0.13
12
77
17
104
1.64
1.09
1.4
1.4
0.53
0.38
g/l
0.64
12
76
50
382
1.32
1.08
1.3
1.3
132.62
231.24
miu/ml
1.17
16
182
143
1231
1.18
1.08
2.3
2.9
7.85
8.17
umol/l
0.07
123
1069
100
834
1.22
1.07
5.6
4.2
0.00
0.12
%
5.74
23
255
10
52
1.93
1.06
1.2
3.3
—
—
—
0
0
7
33
2.13
1.05
1.0
1.0
—
—
—
0
0
319
2917
1.12
1.04
4.9
4.9
2.05
2.77
ug/l
1.18
289
2615
5
22
2.28
1.03
1.0
2.0
—
—
—
0
0
334
3064
1.12
1.03
3.9
3.8
9.62
8.50
mg/mmol
0.12
213
1920
17
106
1.61
1.03
1.4
1.4
—
—
—
0
0
14
226
0.62
1.01
1.1
1.2
—
—
—
0
0
143
1240
1.17
1.00
1.5
1.4
—
—
—
0
0
5
23
2.18
0.98
1.8
1.5
—
—
—
0
0
152
1329
1.16
0.97
1.3
1.3
—
—
—
0
0
9
50
1.81
0.96
2.6
2.7
42411.11
36804.96
ug/l
—
9
50
6
27
2.23
0.93
1.8
1.1
168.60
0.98
u/ml
—
6
18
117
1006
1.18
0.92
3.7
4.2
—
7.36
—
0
6
30
218
1.38
0.92
1.2
1.5
—
—
—
0
0
204
1831
1.14
0.91
1.6
1.6
—
—
—
0
0
11
63
1.75
0.90
1.1
1.0
—
—
—
0
0
24
168
1.44
0.90
3.6
5.3
418.21
365.13
umol/l
0.77
19
150
12
71
1.70
0.89
2.7
2.8
0.16
0.20
e9/l
0.55
12
63
10
56
1.79
0.88
1.5
3.1
—
—
—
0
0
14
87
1.62
0.87
1.1
1.2
—
—
—
0
0
103
882
1.18
0.86
5.2
7.4
8.47
8.95
mmol/l
0.33
96
841
58
469
1.25
0.86
2.3
2.2
3796.45
4951.34
u/l
0.23
22
188
22
153
1.45
0.86
1.7
1.6
—
—
—
0
0
10
57
1.76
0.83
1.3
1.3
—
—
—
0
0
77
645
1.21
0.83
2.4
2.6
—
—
—
0
0
35
267
1.32
0.81
1.1
1.1
—
—
—
0
0
15
97
1.55
0.81
2.2
2.3
43.92
39.66
%
0.67
15
97
27
198
1.37
0.80
1.5
1.8
—
—
—
0
0
25
181
1.39
0.80
2.2
2.7
—
—
—
0
0
6
33
1.82
0.79
1.0
1.5
—
—
—
0
0
8
48
1.67
0.78
1.3
1.1
—
—
—
0
0
43
341
1.27
0.76
1.1
1.2
—
—
—
0
0
96
829
1.17
0.75
2.7
2.7
71.85
71.09
e9/l
0.06
75
630
81
690
1.19
0.74
1.2
1.2
—
—
—
0
0
55
452
1.23
0.73
1.1
1.2
—
—
—
0
0
7
39
1.80
0.72
29.3
32.3
96.43
131.00
ug/l
—
7
31
6
109
0.55
0.72
1.2
1.2
—
—
—
0
0
11
171
0.64
0.72
1.3
1.2
—
—
—
0
0
317
2957
1.09
0.72
3.5
3.2
—
—
—
0
0
37
291
1.28
0.71
3.2
3.8
27.83
30.82
mg/l
0.34
30
234
37
291
1.28
0.71
3.2
3.8
43.86
70.82
mg/l
0.59
30
233
7
41
1.71
0.70
1.0
1.0
—
—
—
0
0
40
319
1.26
0.69
1.2
1.2
—
—
—
0
0
17
118
1.45
0.69
1.2
1.1
—
—
—
0
0
5
27
1.85
0.68
1.6
1.3
55.54
62.34
mu/l
—
5
22
25
187
1.34
0.68
1.2
1.2
4.57
5.90
u/ml
—
7
81
186
1695
1.11
0.67
3.0
2.9
0.71
0.74
ug/l
0.26
133
1096
76
651
1.18
0.67
5.0
4.7
—
—
—
0
0
17
119
1.43
0.67
1.5
1.6
63.45
56.77
%
0.29
11
83
21
282
0.74
0.65
1.6
1.5
—
—
—
0
0
28
215
1.31
0.65
1.2
1.2
—
—
—
0
0
29
224
1.30
0.65
2.3
2.1
130.26
131.30
g/l
0.09
19
171
28
216
1.30
0.63
3.9
4.0
—
—
—
0
0
30
234
1.29
0.63
1.1
1.2
1.38
4.23
u/ml
1.22
16
134
19
138
1.38
0.62
1.7
1.4
—
—
—
0
0
20
147
1.37
0.62
2.0
1.8
—
1552.00
—
0
5
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
2.61
—
0
22
41
497
0.82
0.59
3.1
3.5
—
—
—
0
0
10
64
1.57
0.58
1.1
1.0
—
—
—
0
0
21
276
0.76
0.58
1.5
1.4
—
—
—
0
0
8
53
1.51
0.58
1.5
1.7
—
55.16
—
0
8
82
718
1.15
0.57
1.5
1.3
286.99
214.44
u/ml
0.21
75
663
8
54
1.48
0.57
1.0
1.4
112.37
152.55
nmol/l
—
8
54
239
2227
1.09
0.57
2.0
1.9
—
—
—
0
0
14
98
1.43
0.56
1.5
2.9
0.10
1.65
g/24h
—
5
51
26
204
1.28
0.54
3.0
2.3
15.82
16.23
%
0.25
14
112
20
151
1.33
0.54
4.8
3.3
0.83
1.22
%
0.41
15
141
40
331
1.21
0.54
1.7
2.6
8.85
10.38
g/l
1.53
35
297
17
125
1.36
0.53
1.1
1.3
—
53.97
—
0
7
128
1162
1.11
0.52
1.2
1.3
—
—
—
0
0
49
416
1.18
0.51
1.7
2.0
1.29
1.48
g/l
0.79
41
373
9
65
1.39
0.50
1.0
1.4
1.61
1.56
g/l
—
9
65
14
101
1.39
0.49
2.8
2.5
1.32
1.12
e9/l
0.67
14
92
72
634
1.14
0.49
1.8
1.7
—
—
—
0
0
16
119
1.35
0.48
1.3
1.2
—
—
—
0
0
85
759
1.13
0.47
1.4
1.4
—
—
—
0
0
12
85
1.42
0.47
1.3
1.1
—
—
—
0
0
7
49
1.43
0.46
1.0
1.4
—
—
—
0
0
22
274
0.80
0.43
1.5
1.4
—
—
—
0
0
25
202
1.24
0.43
1.2
1.5
102.22
103.20
u/ml
—
5
38
21
166
1.27
0.43
1.0
1.0
1.94
3.47
u/ml
0.51
13
80
5
32
1.56
0.42
1.4
2.6
258.00
190.59
e6/l
—
5
17
0
15
0.00
0.41
0.0
3.4
—
—
—
0
0
0
15
0.00
0.41
0.0
3.8
—
—
—
0
0
54
474
1.15
0.40
1.1
1.1
—
—
—
0
0
34
288
1.19
0.39
1.7
2.6
36.70
38.09
g/l
0.61
29
255
90
819
1.11
0.38
2.0
2.4
10.40
7.12
ug/l
0.34
68
728
11
80
1.38
0.38
1.0
1.6
0.87
0.99
g/l
0.97
11
80
13
98
1.33
0.37
1.1
1.1
—
—
—
0
0
26
216
1.21
0.37
4.0
3.4
—
—
—
0
0
106
977
1.09
0.36
3.5
4.2
1.32
1.90
mmol/l
1.11
92
794
6
43
1.40
0.35
1.0
1.4
—
—
—
0
0
6
43
1.40
0.35
1.5
1.3
—
—
—
0
0
16
127
1.26
0.33
2.7
1.9
31.06
32.60
pg
0.49
16
127
16
127
1.26
0.33
1.1
1.3
—
—
—
0
0
322
3097
1.05
0.33
1.5
1.5
—
—
—
0
0
6
87
0.69
0.33
1.0
1.4
—
—
—
0
0
17
137
1.24
0.32
2.4
2.1
—
—
—
0
0
11
83
1.33
0.32
1.5
1.2
—
—
—
0
0
25
211
1.19
0.31
1.1
1.1
3.14
5.40
u/ml
0.50
12
114
24
202
1.19
0.31
1.1
1.1
3.74
2.10
u/ml
0.27
12
110
7
52
1.35
0.31
1.3
1.3
24.18
31.32
nmol/l
—
7
42
19
156
1.22
0.31
1.4
1.4
—
—
—
0
0
18
147
1.23
0.30
1.0
1.1
3.55
5.99
u/ml
—
10
56
41
362
1.14
0.30
3.4
4.0
1.36
1.35
mmol/l
0.02
41
355
52
467
1.12
0.30
3.0
3.1
25.50
25.28
mmol/l
0.19
52
446
14
111
1.26
0.30
1.3
1.4
—
—
—
0
0
13
102
1.28
0.30
1.6
1.3
9042.38
1658.50
e6/l
—
8
68
12
93
1.29
0.30
1.7
1.3
129341.83
41230.60
e6/l
—
6
52
19
157
1.21
0.29
2.5
3.2
—
—
—
0
0
30
260
1.16
0.29
1.8
1.2
—
—
—
0
0
87
806
1.09
0.28
2.4
2.9
160.49
182.14
ng/l
0.24
79
741
11
85
1.30
0.28
1.5
1.3
—
—
—
0
0
14
172
0.81
0.27
1.0
1.2
—
—
—
0
0
31
271
1.15
0.27
1.1
1.3
—
—
—
0
0
13
104
1.25
0.26
3.2
3.5
—
—
—
0
0
41
457
0.89
0.26
1.8
1.8
—
—
—
0
0
22
256
0.86
0.25
3.1
4.6
—
—
—
0
0
27
235
1.15
0.25
1.6
3.3
28.36
34.58
umol/l
1.35
22
211
14
114
1.23
0.25
7.9
4.2
—
—
—
0
0
90
841
1.08
0.25
4.3
3.3
—
—
—
0
0
12
148
0.81
0.24
2.0
2.1
13.25
13.13
%
0.14
12
148
60
553
1.09
0.23
2.4
3.1
64.58
54.19
u/ml
0.10
60
533
73
680
1.08
0.22
4.2
2.9
—
—
—
0
0
5
40
1.25
0.22
1.2
1.4
—
—
—
0
0
5
40
1.25
0.22
1.6
1.4
—
3.60
%
—
0
10
105
993
1.06
0.22
3.0
4.2
5.41
28.02
ug/l
1.62
84
808
14
167
0.84
0.21
1.9
1.2
15.72
34.95
u/l
0.99
14
147
380
3891
0.97
0.21
2.5
2.6
—
—
—
0
0
0
13
0.00
0.21
0.0
3.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
267.15
—
0
8
22
192
1.15
0.20
2.8
2.3
—
—
—
0
0
26
230
1.13
0.20
1.3
1.2
267.73
260.09
u/ml
0.04
11
134
10
123
0.81
0.20
1.2
1.3
—
—
nmol/l
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
16
136
1.18
0.20
1.1
1.3
—
0.52
nmol/l
—
0
10
118
1238
0.95
0.20
1.4
1.4
—
—
—
0
0
12
99
1.21
0.19
1.6
1.3
61840.00
196759.97
e6/l
—
5
65
41
375
1.10
0.19
4.1
3.8
0.24
0.30
g/l
0.36
21
164
6
52
1.15
0.19
1.0
1.0
143.00
178.91
iu/ml
—
6
52
29
262
1.11
0.17
4.2
2.4
—
—
—
0
0
102
973
1.05
0.17
1.8
2.4
0.21
0.22
g/l
0.03
95
913
13
110
1.18
0.17
4.3
2.7
—
—
—
0
0
5
67
0.75
0.17
1.0
1.3
142.86
173.42
pmol/l
—
5
67
16
183
0.87
0.16
1.1
1.7
—
—
—
0
0
8
72
1.11
0.16
2.6
3.9
—
—
—
0
0
6
77
0.78
0.15
1.0
1.0
—
—
—
0
0
9
81
1.11
0.15
1.0
1.1
—
—
—
0
0
39
420
0.93
0.15
1.0
1.1
—
—
—
0
0
8
97
0.82
0.13
1.9
1.6
—
—
—
0
0
37
344
1.08
0.13
1.4
1.5
1.15
1.19
g/l
0.31
37
323
96
922
1.04
0.13
4.3
3.7
—
—
—
0
0
63
598
1.06
0.13
1.3
1.3
—
—
—
0
0
42
448
0.94
0.13
2.8
3.2
0.64
0.64
%
0.01
42
448
20
180
1.11
0.13
1.1
1.1
—
—
—
0
0
10
117
0.85
0.13
1.2
1.3
—
—
—
0
0
18
161
1.12
0.13
1.4
1.3
—
—
—
0
0
19
171
1.11
0.12
1.2
1.1
50.28
96.84
iu/ml
—
5
44
129
1250
1.04
0.12
1.8
1.7
—
—
—
0
0
20
181
1.11
0.12
1.5
1.6
—
—
—
0
0
105
1087
0.96
0.12
1.4
1.4
—
—
—
0
0
11
95
1.16
0.11
1.2
1.3
2.94
2.05
u/ml
—
5
52
11
95
1.16
0.11
1.0
1.1
—
—
—
0
0
41
386
1.06
0.11
4.2
4.6
—
—
—
0
0
5
45
1.11
0.09
1.0
1.0
2043.20
1703.84
miu/ml
—
5
45
5
46
1.09
0.09
2.2
2.3
—
—
—
0
0
22
203
1.09
0.09
1.1
1.1
0.50
0.72
u/ml
—
10
98
16
176
0.91
0.09
1.4
1.4
—
—
—
0
0
126
1228
1.03
0.09
1.5
1.7
—
—
—
0
0
6
55
1.09
0.09
1.7
2.9
1553.33
2043.20
ml
—
6
50
6
55
1.09
0.09
1.0
1.7
—
—
—
0
0
15
136
1.10
0.08
1.0
1.0
0.01
0.51
u/ml
—
6
44
8
76
1.05
0.07
1.3
1.1
—
—
—
0
0
12
108
1.11
0.07
1.8
2.2
—
—
—
0
0
8
91
0.88
0.06
1.6
2.4
—
—
—
0
0
37
386
0.96
0.06
1.2
1.2
—
—
—
0
0
26
247
1.05
0.05
2.1
2.3
9.62
118.92
ug/min
4.17
13
150
19
202
0.94
0.05
1.1
1.1
—
—
—
0
0
16
149
1.07
0.05
2.4
2.7
7.24
9.39
umol/l
—
9
108
87
888
0.98
0.05
1.4
1.4
—
—
—
0
0
12
130
0.92
0.04
1.0
1.2
—
—
—
0
0
39
378
1.03
0.04
2.6
2.7
—
—
—
0
0
19
200
0.95
0.03
1.1
1.1
—
—
—
0
0
13
121
1.08
0.03
2.6
2.6
3.99
4.01
mmol/l
0.07
13
121
13
121
1.08
0.03
2.6
2.6
106.62
105.61
mmol/l
0.45
13
121
23
220
1.05
0.03
5.0
4.0
2.41
2.37
mmol/l
0.03
17
148
40
389
1.03
0.03
2.0
1.8
2.56
2.02
ug/l
0.10
29
348
31
301
1.03
0.02
3.8
4.1
3.79
3.86
mmol/l
0.59
31
296
18
172
1.05
0.02
1.1
1.1
—
—
—
0
0
12
126
0.95
0.00
2.3
2.6
—
—
—
0
0
24
234
1.03
0.00
2.8
3.5
22.51
26.09
mg/l
0.20
13
151
38
376
1.01
0.00
3.8
3.4
3143.94
3702.39
u/ml
0.05
33
328
12
119
1.01
0.00
2.8
2.6
—
—
—
0
0
40
401
1.00
0.00
1.7
1.6
—
—
—
0
0
22
225
0.98
0.00
3.8
4.1
—
—
—
0
0
24
245
0.98
0.00
1.5
1.6
13295.47
13508.85
e6/l
0.01
17
179
5
50
1.00
0.00
1.0
1.2
—
—
—
0
0
7
76
0.92
0.00
1.3
1.3
—
—
—
0
0
5
50
1.00
0.00
1.0
1.4
143.40
168.35
mmol/24h
—
5
50
0
6
0.00
-0.00
0.0
2.2
—
1.92
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
12.14
—
0
8
8
84
0.95
-0.00
1.5
2.1
—
—
—
0
0
9
91
0.99
-0.00
1.6
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
79
1.01
-0.00
1.6
1.4
61.00
78.61
umol/l
—
8
79
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
18
180
1.00
-0.00
1.4
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
170.78
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
35.40
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.1
—
—
—
0
0
8
83
0.96
-0.00
1.1
1.1
—
88.33
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
0.04
—
0
5
6
68
0.88
-0.00
1.2
1.2
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.2
90.80
455.90
u/l
—
5
51
0
8
0.00
-0.00
0.0
3.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
326.83
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_VERTISTRAB and mortality.

Females

Parameter HR [95% CI] p-value
H7_VERTISTRAB 0.921 [0.77, 1.09] 0.349
Birth year 0.992 [0.98, 1.0] 0.078

During the follow-up period (1.1.1998 — 31.12.2019), 229 out of 3370 females with H7_VERTISTRAB died.

Males

Parameter HR [95% CI] p-value
H7_VERTISTRAB 1.046 [0.89, 1.23] 0.586
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 278 out of 2894 males with H7_VERTISTRAB died.

Mortality risk

Mortality risk for people of age

years, who have H7_VERTISTRAB.

N-year risk Females Males
1 0.086% 0.209%
5 0.507% 1.234%
10 1.248% 2.985%
15 2.428% 5.589%
20 4.468% 9.332%

Relationships between endpoints

↥

Index endpoint: H7_VERTISTRAB – Vertical strabismus

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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