Pyoderma

L12_PYODERMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L08.0
  • Hospital discharge: ICD-9 6860
  • Hospital discharge: ICD-8 68600
  • Cause of death: ICD-10 L08.0
  • Cause of death: ICD-9 6860
  • Cause of death: ICD-8 68600

2 out of 7 registries used, show all original rules.

736

4. Check minimum number of events

None

736

5. Include endpoints

None

736

6. Filter based on genotype QC (FinnGen only)

717

Control definitions (FinnGen only)

Control exclude
L12_INFECT_SKIN

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L08
Name in latin
Pyoderma

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7378 3141 4153
Only index persons 5683 2533 3150
Unadjusted period prevalence (%)
Whole population 0.10 0.09 0.12
Only index persons 0.11 0.09 0.12
Median age at first event (years)
Whole population 39.59 39.40 39.51
Only index persons 37.57 38.25 37.03

-FinnGen-

Key figures

All Female Male
Number of individuals 717 368 349
Unadjusted period prevalence (%) 0.14 0.13 0.16
Median age at first event (years) 44.09 41.77 46.54

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
736
Matched controls
7360
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L08.0
ICD-10 Finland
Pyoderma
2107.3
307.7
523
9
68600
ICD-8 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
+∞
178.6
164
*
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
13.3
78.3
77
64
A46
ICD-10 Finland
Erysipelas
4.7
65.7
189
509
6860A
ICD-9 Finland
Other local infections of skin and subcutaneous tissue, Pyoderma
+∞
58.1
55
*
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
4.1
51.6
174
521
J01FF01
ATC
clindamycin; systemic
3.3
51.1
289
1210
E0000UV, ,
ATC
3.0
47.9
398
2057
L20.0
ICD-10 Finland
Besnier prurigo
4.7
45.1
115
277
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
13.0
43.9
43
35
E000001, ,
ATC
3.2
42.9
220
856
D07BA04
ATC
hydrocortisone and antiseptics; topical
4.2
42.5
127
345
TQW80
NOMESCO Finland
Local dermatologic skincare
8.6
40.2
53
66
L30.9
ICD-10 Finland
Dermatitis, unspecified
3.1
39.4
211
838
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
8.9
37.7
48
57
D09AB01
ATC
zinc bandage without supplements; topical
10.5
35.7
40
40
D07AB08
ATC
desonide; topical
3.5
34.6
135
439
D07AC01
ATC
betamethasone; topical
2.6
34.4
326
1724
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
8.7
33.3
43
52
L30.3
ICD-10 Finland
Infective dermatitis
6.0
31.3
57
101
S97
ICPC
Chronic ulcer skin
4.5
30.2
78
188
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.2
29.6
136
487
D07AD01
ATC
clobetasol; topical
2.9
29.0
162
648
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.5
28.6
108
342
D07AC13
ATC
mometasone; topical
2.4
27.5
259
1337
D07BC01
ATC
betamethasone and antiseptics; topical
3.1
27.5
131
478
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.0
26.3
48
85
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
8.0
26.1
36
47
D07CC01
ATC
betamethasone and antibiotics; topical
2.9
25.9
139
541
D07AA02
ATC
hydrocortisone; topical
2.8
25.1
148
606
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.3
23.8
101
343
N05BB01
ATC
hydroxyzine; systemic
3.8
23.3
77
222
D06AX01
ATC
fusidic acid; topical
3.2
23.1
102
354
D07AB02
ATC
hydrocortisone butyrate; topical
2.3
22.9
258
1420
E000002, ,
ATC
3.0
22.3
114
430
E000003, ,
ATC
4.3
22.3
60
149
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
7.6
22.2
32
44
-, ,
ICD-10 Finland
6.6
22.0
36
57
H02AB06
ATC
prednisolone; systemic
2.1
21.8
385
2512
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
21.6
362
2313
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
6.5
21.2
35
56
J01DB01
ATC
cefalexin; oral
2.7
20.8
628
5030
J01DA01
ATC
[U] cefalexin
2.1
20.7
483
3472
R06AE07
ATC
cetirizine; oral
2.1
19.8
344
2206
J01MA12
ATC
levofloxacin; systemic
2.4
19.7
164
786
J01CF05
ATC
flucloxacillin; systemic
3.8
19.5
62
174
J01DA09
ATC
[U] cefadroxil
2.2
18.8
224
1243
L01.0
ICD-10 Finland
Impetigo [any organism] [any site]
7.9
18.8
26
34
C03CA01
ATC
furosemide; systemic
2.1
18.7
236
1339
D05BB02
ATC
acitretin; oral
5.6
17.7
34
63
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.6
17.3
114
489
XQ802
NOMESCO Finland
Epicutan test
4.1
17.2
49
127
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.8
16.6
52
144
R60.0
ICD-10 Finland
Localized oedema
2.6
16.1
102
428
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.6
16.0
99
411
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
15.9
87
339
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.1
15.8
70
242
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
15.4
122
568
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
15.2
95
396
69282
ICD-8 Finland
Other eczema and dermatitis, E microbis
20.6
15.2
22
11
D02AX
ATC
Other emollients and protectives
4.4
15.2
38
89
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
15.1
136
668
D07XC01
ATC
betamethasone; topical
2.4
15.1
112
506
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
14.6
109
494
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
6.0
14.5
26
45
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.4
14.4
114
530
J01MA02
ATC
ciprofloxacin; systemic
1.9
14.3
289
1896
L03.9
ICD-10 Finland
Cellulitis, unspecified
13.7
14.3
24
18
D07XB05
ATC
dexamethasone; topical
4.7
14.1
33
73
D11AX14
ATC
[U] tacrolimus
24.3
13.8
19
8
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
13.8
78
309
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
4.9
13.6
30
63
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.1
13.6
38
97
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
4.1
13.6
38
97
D02AE01
ATC
carbamide; topical
3.0
13.5
62
219
H02AB07
ATC
prednisone; oral
2.3
13.4
116
560
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.1
13.3
58
199
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.7
13.1
43
123
L30.0
ICD-10 Finland
Nummular dermatitis
3.8
13.1
40
109
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.0
13.0
181
1045
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
13.0
90
393
NHQ40
NOMESCO Finland
Amputation of toe
6.3
13.0
22
36
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.6
12.8
43
125
S76
ICPC
Skin infection other
3.3
12.7
49
156
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.9
12.7
28
59
L89
ICD-10 Finland
Decubitus ulcer and pressure area
5.6
12.7
24
44
D01AC02
ATC
miconazole; topical
2.7
12.6
71
280
E000006, ,
ATC
2.8
12.6
65
245
J01AA07
ATC
tetracycline; systemic
2.2
12.5
120
603
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.1
12.5
53
179
SPAT1254
SPAT
Administration of medicine
2.2
12.2
115
573
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
6.1
12.2
21
35
N06AB04
ATC
citalopram; systemic
2.0
12.2
166
950
N02AX02
ATC
tramadol; systemic, rectal
1.8
12.1
315
2203
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.5
11.8
29
67
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
5.8
11.5
21
37
L04AX01
ATC
azathioprine; systemic
3.4
11.5
42
129
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
11.5
100
482
SPAT1255
SPAT
Intravenous administration of medicine
2.8
11.4
57
211
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
11.4
125
660
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
11.4
100
484
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.1
11.2
49
168
D05AX52
ATC
calcipotriol, combinations; topical
3.1
11.2
48
163
ZXD05
NOMESCO Finland
Urgent procedure
1.8
11.1
228
1482
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
11.0
190
1169
ZZA00
NOMESCO Finland
Split skin graft
4.1
11.0
30
75
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
4.9
11.0
24
50
SPAT1172
SPAT
Guidance concerning hydration
5.5
10.9
21
39
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.7
10.9
62
246
D11AH01
ATC
tacrolimus; topical
10.8
10.8
20
19
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
10.8
257
1738
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
4.8
10.8
24
51
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.2
10.7
97
476
69299
ICD-8 Finland
Other eczema and dermatitis, Due to other and unspecified cause
60.9
10.6
12
*
L04AA01
ATC
[U] ciclosporin
8.7
10.6
22
26
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
10.4
194
1220
S29
ICPC
Skin symptom/complaint other
2.0
10.4
136
765
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
10.2
229
1518
R41.0
ICD-10 Finland
Disorientation, unspecified
4.1
10.1
28
71
R50.9
ICD-10 Finland
Fever, unspecified
2.0
10.1
118
637
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.7
10.0
56
220
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.1
10.0
42
141
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
26.4
9.8
13
5
S18
ICPC
Laceration/cut
1.7
9.8
316
2303
SPAT1260
SPAT
Consultation of another employee
1.9
9.7
127
713
J01CE08
ATC
benzathine benzylpenicillin; parenteral
11.6
9.6
17
15
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
9.5
97
497
E66.8
ICD-10 Finland
Other obesity
2.9
9.4
44
157
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.7
9.3
29
80
L28
ICPC
Limited function/disability (L)
1.9
9.3
123
691
L04AA06
ATC
mycophenolic acid; systemic
4.8
9.3
21
45
M79.6
ICD-10 Finland
Pain in limb
1.6
9.3
285
2043
L04AX03
ATC
methotrexate; systemic
2.2
9.1
77
366
L88
ICD-10 Finland
Pyoderma gangrenosum
37.2
9.0
11
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
8.9
202
1335
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.2
8.9
77
370
A10AE04
ATC
insulin glargine; parenteral
2.2
8.8
75
358
SPAT1229
SPAT
Assessment of need for aid
2.5
8.7
57
242
6929B
ICD-9 Finland
Contact dermatitis and other eczema, Unspecified cause[ECZEMA INFECTIOSUM]
50.6
8.7
10
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
8.6
72
341
SPAT1301
SPAT
No procedures
1.7
8.6
213
1441
SPAT1216
SPAT
Assessment of functional ability
1.9
8.5
108
599
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.5
8.4
29
86
L20
ICD-10 Finland
Atopic dermatitis
3.4
8.4
30
91
S87
ICPC
Dermatitis/atopic eczema
3.7
8.3
26
72
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
9.6
8.3
16
17
N03AX16
ATC
[U] pregabalin
1.7
8.3
163
1034
F10.24
ICD-10 Finland
Alcohol depence active use
4.3
8.2
21
50
B18.2
ICD-10 Finland
Chronic viral hepatitis C
6.6
8.2
20
31
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
8.2
131
782
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.9
8.2
39
141
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
6.9
8.1
19
28
L73.2
ICD-10 Finland
Hidradenitis suppurativa
6.9
8.1
19
28
D11AX15
ATC
[U] pimecrolimus
33.7
8.1
10
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
8.1
102
564
AA1AD
NOMESCO Finland
CT of head and brain
1.7
8.1
180
1182
UJF32
NOMESCO Finland
Coloscopy
1.7
8.0
178
1168
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
8.0
135
820
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.4
7.9
54
235
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
3.9
7.8
23
61
D07CB01
ATC
triamcinolone and antibiotics; topical
4.1
7.8
21
52
A10AB05
ATC
insulin aspart; parenteral
2.3
7.8
60
274
N05BA04
ATC
oxazepam; oral
1.7
7.8
179
1182
N05CD07
ATC
temazepam; oral
2.0
7.8
89
475
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.2
7.8
30
96
L17
ICPC
Foot/toe symptom/complaint
1.6
7.7
195
1320
134
Kela drug reimbursment
General erythroderma
15.2
7.7
12
8
69240
ICD-8 Finland
Other eczema and dermatitis, Due to other chemicals
45.5
7.7
9
*
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
7.7
131
796
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
7.7
67
323
N03AX12
ATC
[U] gabapentin; oral
1.8
7.7
119
703
H02AB04
ATC
methylprednisolone; systemic
1.9
7.7
104
589
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.5
7.6
26
77
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.2
7.6
63
298
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
7.6
97
539
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
7.5
136
841
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.1
7.5
70
347
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.0
7.5
21
54
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
7.5
162
1054
N06AX11
ATC
mirtazapine; oral
1.6
7.4
231
1644
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.1
7.4
20
50
N05BA01
ATC
diazepam; systemic, rectal
1.9
7.4
96
536
NF1AA
NOMESCO Finland
Hip X-ray examination
2.2
7.3
60
282
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
7.3
147
936
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.9
7.3
34
122
SPAT1263
SPAT
Sampling
1.5
7.2
280
2093
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
7.2
208
1455
S20.2
ICD-10 Finland
Contusion of thorax
2.6
7.0
39
153
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.3
7.0
52
234
S01
ICPC
Pain/tenderness of skin
2.9
7.0
33
119
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
6.9
158
1039
A41.9
ICD-10 Finland
Sepsis, unspecified
3.0
6.9
30
103
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
6.9
109
647
XQ800
NOMESCO Finland
Prick test
2.3
6.8
54
250
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.7
6.8
21
58
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.7
6.8
21
58
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.1
6.7
28
94
D05AX02
ATC
calcipotriol; topical
2.9
6.7
30
105
M05BA04
ATC
alendronic acid; oral
2.2
6.7
58
279
N03AE01
ATC
clonazepam; systemic
2.5
6.6
42
176
M10.9
ICD-10 Finland
Gout, unspecified
2.3
6.6
48
214
D11AH02
ATC
pimecrolimus; topical
12.4
6.6
11
9
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.6
280
2125
R06AX22
ATC
ebastine; oral
1.7
6.6
116
711
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
6.6
201
1419
L04AD01
ATC
ciclosporin; systemic
3.9
6.6
19
50
J02AC01
ATC
fluconazole; systemic
1.5
6.6
254
1889
NG4AA
NOMESCO Finland
Lower leg X-ray examination
3.1
6.6
27
90
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
10.1
6.5
12
12
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
6.5
67
344
B00.10
ICD-10 Finland
Herpes simplex facialis
6.9
6.5
15
22
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
6.9
6.5
15
22
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
5.8
6.5
17
30
N05AA02
ATC
levomepromazine; systemic
2.7
6.5
34
130
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
4.0
6.5
18
46
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.6
6.5
36
142
K05.31
ICD-10 Finland
Periodontitis pronounced
1.9
6.4
78
425
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
7.5
6.4
14
19
N05AH04
ATC
quetiapine; oral
1.7
6.4
121
756
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
6.4
62
312
A02BC02
ATC
pantoprazole; systemic
1.5
6.4
453
3806
L02.8
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of other sites
6.6
6.4
15
23
F05.9
ICD-10 Finland
Delirium, unspecified
5.2
6.4
18
35
R06AE09
ATC
levocetirizine; oral
1.8
6.3
99
586
205
Kela drug reimbursment
Chronic hypertension
1.6
6.3
173
1190
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
6.3
50
233
J01FA01
ATC
erythromycin; systemic
1.8
6.2
90
519
L30.8
ICD-10 Finland
Other specified dermatitis
3.1
6.2
25
82
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
6.2
60
301
T78.4
ICD-10 Finland
Allergy, unspecified
2.7
6.2
33
127
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
6.2
45
201
P01AB01
ATC
metronidazole; oral, rectal
1.5
6.2
265
2008
N02AA05
ATC
oxycodone; systemic
1.7
6.2
114
707
N06AB03
ATC
fluoxetine; oral
1.8
6.1
89
515
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.7
6.1
19
53
WW200
NOMESCO Finland
Immunization
3.2
6.1
23
73
J04BA02
ATC
dapsone; oral
10.1
6.0
11
11
L14
ICPC
Leg/thigh symptom/complaint
2.1
6.0
56
277
N07BA03
ATC
varenicline; oral
2.5
6.0
37
153

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
177
610
3.50
41.97
2.9
1.6
—
—
—
0
0
276
1465
2.41
27.57
5.4
4.0
—
—
—
0
0
158
769
2.34
18.22
2.7
1.9
—
—
—
0
0
392
2704
1.96
17.69
9.1
6.2
—
—
—
0
0
367
2513
1.92
16.55
9.6
6.2
1.21
1.21
mmol/l
0.01
333
2284
392
2765
1.89
15.92
9.6
6.8
1.21
1.21
mmol/l
0.16
335
2352
411
2969
1.87
15.23
9.1
6.1
0.22
0.19
e9/l
2.31
347
2619
397
2867
1.84
14.43
9.0
5.7
0.62
0.58
e9/l
2.17
338
2493
397
2874
1.83
14.24
9.0
5.7
0.04
0.04
e9/l
1.48
338
2501
341
2387
1.80
13.41
6.7
4.8
35.00
35.77
g/l
1.59
316
2234
397
2940
1.76
12.59
9.2
5.7
1.92
1.94
e9/l
0.10
350
2620
398
2962
1.75
12.29
7.0
6.3
10.57
11.84
umol/l
1.00
381
2803
435
3325
1.75
12.17
12.3
8.9
4.52
4.02
e9/l
3.85
370
2917
131
693
2.08
11.93
1.6
1.4
—
—
—
0
0
102
491
2.25
11.78
9.7
7.5
9.04
9.14
mmol/l
0.06
97
470
429
3297
1.72
11.48
7.3
4.8
6.88
6.63
mmol/l
1.33
410
3071
59
226
2.75
11.09
1.3
1.3
—
—
—
0
0
366
2713
1.69
11.03
10.4
6.1
8.40
8.67
%
0.81
337
2553
372
2778
1.69
10.83
9.6
5.9
26.19
28.10
%
2.30
342
2619
349
2565
1.69
10.78
16.9
12.7
1.24
1.24
inr
0.00
83
746
116
609
2.07
10.72
8.4
8.2
11.41
12.21
kpa
1.20
108
587
116
609
2.07
10.72
8.4
8.2
5.26
5.05
kpa
1.10
106
584
132
730
1.98
10.56
9.4
6.1
1.05
1.05
mmol/l
0.06
126
674
154
903
1.89
10.35
4.7
3.8
0.79
0.82
mmol/l
3.01
145
844
365
2740
1.66
10.20
9.3
5.7
58.77
56.97
%
1.78
336
2586
361
2703
1.66
10.19
9.6
5.8
2.88
2.90
%
0.05
331
2538
215
1402
1.75
10.17
8.4
6.6
—
—
—
0
0
350
2611
1.65
9.94
9.2
5.9
0.67
0.68
%
0.06
320
2445
114
614
2.01
9.79
8.5
8.2
1.00
1.06
mmol/l
0.06
88
485
303
2187
1.66
9.75
2.4
1.9
91.42
93.74
pmol/l
0.41
156
1118
529
4405
1.71
9.63
10.0
7.3
77.77
78.93
u/l
0.29
502
4150
91
455
2.14
9.52
4.4
3.1
—
—
—
0
0
196
1280
1.72
9.08
4.5
3.5
—
—
—
0
0
157
975
1.78
8.64
1.9
1.7
1227.23
1183.74
nmol/l
0.21
118
733
98
524
2.00
8.56
2.6
2.3
0.20
0.21
g/l
0.51
91
488
236
1641
1.64
8.55
6.6
3.9
7.40
7.40
ph
0.11
43
303
88
453
2.07
8.52
2.6
2.3
4.06
8.36
ug/l
2.61
74
394
190
1250
1.70
8.50
1.9
1.9
0.87
1.07
mg/l
1.06
138
961
59
260
2.38
8.34
7.6
5.8
25.59
24.91
mmol/l
0.66
53
245
117
673
1.88
8.23
10.7
6.5
104.25
104.17
mmol/l
0.06
117
673
236
1655
1.63
8.21
2.4
2.1
151.33
284.02
u/l
1.43
213
1559
287
2114
1.59
8.11
4.3
3.4
27.30
39.39
ng/l
1.83
191
1435
63
290
2.28
8.07
7.2
5.3
—
—
—
0
0
233
1636
1.62
8.03
3.5
2.7
—
—
—
0
0
304
2285
1.56
7.79
3.0
2.3
72.31
76.37
nmol/l
1.81
266
2047
77
390
2.09
7.78
7.4
5.0
5.34
5.15
kpa
1.11
72
375
76
386
2.08
7.63
7.5
5.0
7.43
7.41
ph
—
8
44
506
4276
1.59
7.58
5.1
3.9
14.63
11.43
mm/h
3.64
469
3951
201
1381
1.63
7.49
3.1
2.0
3.18
2.99
mg/l
0.49
166
1181
136
852
1.73
7.16
3.0
2.4
11.55
13.61
umol/l
2.32
120
798
125
766
1.76
7.11
3.0
2.3
2.32
2.33
g/l
0.07
109
714
244
1776
1.56
7.05
3.3
2.4
49.90
61.41
u/l
3.20
224
1651
119
727
1.76
6.83
3.0
2.4
20.81
23.68
%
1.35
100
620
195
1356
1.60
6.83
2.9
2.2
—
—
—
0
0
202
1421
1.58
6.72
5.4
4.0
91.30
90.68
%
0.13
195
1392
48
213
2.34
6.71
2.4
1.9
2.79
2.88
ug/l
0.01
41
186
257
1911
1.53
6.67
4.1
3.3
29.36
31.64
u/l
0.77
240
1829
252
1867
1.53
6.65
3.6
3.4
2.37
2.35
mmol/l
1.20
212
1653
67
343
2.05
6.59
4.3
5.9
—
—
—
0
0
57
282
2.11
6.14
10.9
9.9
24.24
24.22
mmol/l
0.02
51
276
77
427
1.90
6.04
3.8
2.9
69.70
70.36
e9/l
0.06
59
329
214
1559
1.53
6.00
4.1
3.1
1780.36
1237.69
ng/l
0.85
178
1326
110
682
1.72
5.97
2.9
2.4
139.46
122.87
ug/g
0.27
83
551
213
1552
1.52
5.96
4.1
2.9
1.02
0.45
e6/l
0.97
161
1164
80
452
1.86
5.93
14.8
8.7
—
—
—
0
0
135
887
1.64
5.89
3.1
2.8
3.41
2.01
e6/l
0.66
75
480
43
195
2.28
5.75
9.3
4.7
—
—
—
0
0
108
674
1.71
5.72
1.9
1.6
—
—
—
0
0
74
413
1.88
5.70
4.8
4.0
84.62
79.66
ng/l
0.18
60
366
466
3982
1.46
5.69
5.3
4.0
—
—
—
0
0
87
513
1.79
5.62
4.3
4.2
—
—
—
0
0
207
1520
1.50
5.52
4.1
2.9
—
—
—
0
0
317
2532
1.44
5.49
13.5
9.1
0.00
0.00
e9/l
0.29
258
2081
91
548
1.75
5.47
3.0
2.0
362.80
376.16
nmol/l
0.19
84
508
37
161
2.37
5.44
1.2
1.1
—
—
—
0
0
229
1722
1.48
5.42
3.8
3.1
7.89
7.82
mmol/l
0.06
185
1455
236
1795
1.46
5.24
2.9
2.3
—
—
—
0
0
13
22
5.99
5.24
1.0
1.1
322.50
144.17
iu/ml
1.34
13
22
73
421
1.81
5.08
1.8
1.5
—
—
—
0
0
161
2190
0.66
5.06
2.7
2.7
—
—
—
0
0
84
506
1.75
5.05
8.3
4.1
2.64
1.73
mmol/l
1.54
74
408
126
848
1.59
4.95
2.6
2.6
30.35
29.61
s
0.62
120
830
211
1588
1.46
4.90
3.7
3.2
1844.54
267.97
mg/l
1.48
143
1031
84
511
1.73
4.88
3.3
2.3
30.09
34.52
u/l
0.70
75
438
21
73
2.93
4.80
1.7
1.4
—
—
—
0
0
26
103
2.58
4.67
1.4
1.2
—
—
—
0
0
31
135
2.35
4.58
4.4
1.7
—
—
—
0
0
56
307
1.89
4.58
1.5
1.2
—
—
—
0
0
22
81
2.77
4.55
5.7
1.6
—
—
—
0
0
631
5828
1.58
4.52
23.8
13.0
27.47
23.41
mg/l
2.11
541
4559
196
1475
1.45
4.50
3.9
2.7
2355.12
6774.63
umol/l
1.16
166
1319
18
60
3.05
4.42
1.9
1.5
—
—
—
0
0
43
219
2.02
4.35
1.7
2.0
1.65
1.47
g/l
0.53
37
192
497
4408
1.39
4.20
4.3
3.7
14.63
14.69
pmol/l
0.19
450
4008
34
161
2.17
4.16
4.1
1.4
—
—
—
0
0
43
223
1.99
4.15
2.3
1.7
—
—
—
0
0
90
584
1.62
4.11
3.9
2.7
1.82
1.77
%
0.20
76
529
71
433
1.71
4.11
2.9
3.0
66.76
66.89
g/l
0.05
61
392
61
358
1.77
4.04
1.4
1.2
2184.44
242.29
u/ml
1.13
54
327
220
1722
1.40
4.00
4.2
3.0
38.31
95.77
e6/l
0.77
165
1317
30
138
2.22
3.94
1.2
1.3
—
—
—
0
0
214
1671
1.40
3.94
4.2
3.8
8.50
9.68
mg/mmol
0.17
137
1060
303
2505
1.36
3.90
3.3
2.7
134.24
120.06
ug/l
0.35
279
2332
251
2016
1.37
3.88
4.7
3.5
124.27
100.19
e6/l
0.10
178
1409
73
456
1.67
3.87
5.7
4.3
0.72
1.03
%
0.77
39
170
320
2686
1.34
3.66
3.1
2.5
—
—
—
0
0
51
293
1.80
3.64
9.6
11.3
—
—
—
0
0
121
866
1.48
3.56
1.8
1.6
—
—
—
0
0
26
118
2.25
3.55
7.0
3.7
—
—
—
0
0
169
1289
1.40
3.53
1.7
1.5
19.95
20.89
nmol/l
0.35
136
1082
8
13
6.21
3.51
1.0
1.2
—
—
—
0
0
10
22
4.59
3.44
3.5
2.0
—
—
—
0
0
335
2850
1.32
3.43
4.4
3.5
0.00
0.01
estimate
0.50
52
516
66
419
1.63
3.31
1.5
1.4
—
—
—
0
0
38
207
1.88
3.23
4.9
3.5
0.71
0.23
g/l
0.59
21
89
10
24
4.21
3.20
1.0
1.8
67.40
63.88
umol/l
—
5
16
70
455
1.60
3.20
1.3
1.2
—
—
—
0
0
330
2821
1.31
3.19
4.4
3.5
0.00
0.00
estimate
0.50
58
566
38
208
1.87
3.19
1.9
2.6
—
—
—
0
0
20
86
2.36
3.10
1.2
1.1
—
—
—
0
0
10
25
4.04
3.09
38.0
26.5
6.50
7.70
ug/l
—
10
20
52
317
1.69
3.06
7.1
3.6
123.69
129.06
g/l
0.97
52
310
66
429
1.59
3.03
6.1
4.4
0.06
0.14
%
0.87
34
144
64
414
1.60
3.00
5.8
4.1
1.52
0.61
%
0.62
33
141
327
2815
1.29
2.93
5.5
4.7
0.00
0.00
estimate
-0.00
55
536
147
1134
1.37
2.84
1.3
1.5
2.56
2.45
g/l
0.31
80
695
11
33
3.37
2.82
1.5
1.4
150.64
155.56
nmol/l
0.07
11
33
17
71
2.43
2.82
4.7
4.1
—
—
—
0
0
21
97
2.20
2.79
1.1
1.1
—
—
—
0
0
66
439
1.55
2.76
2.0
2.7
10.42
10.39
g/l
0.02
55
403
5
6
8.38
2.75
1.0
1.3
—
—
—
0
0
269
2272
1.29
2.75
4.3
3.3
5.83
5.84
ph
0.01
12
182
439
3943
1.28
2.73
4.5
3.0
53.76
48.05
u/l
0.62
415
3690
199
1617
1.32
2.71
4.3
3.8
—
—
—
0
0
574
5344
1.34
2.71
5.4
4.5
1.93
2.12
mu/l
0.38
525
4887
131
1004
1.37
2.63
3.0
3.0
2.46
2.45
mmol/l
0.40
114
886
55
355
1.59
2.62
2.3
2.6
—
—
—
0
0
163
1294
1.33
2.60
1.3
1.3
0.71
1.78
u/ml
2.07
33
359
150
1177
1.34
2.59
3.6
2.4
8.83
5.56
e6/l
0.60
131
1054
34
193
1.80
2.59
4.4
1.4
—
—
—
0
0
104
769
1.41
2.58
1.4
1.2
—
—
—
0
0
12
44
2.76
2.55
2.9
3.0
35.29
42.20
%
—
7
26
5
7
7.18
2.55
1.4
1.1
21.02
16.11
umol/l
—
5
7
123
942
1.37
2.48
1.3
1.3
20.10
12.99
u/ml
0.35
49
366
7
16
4.41
2.48
1.1
2.2
—
—
—
0
0
19
89
2.16
2.46
1.5
1.5
37.56
24.80
u/l
0.60
13
75
60
402
1.54
2.45
6.1
4.4
0.19
0.18
%
0.00
27
119
25
133
1.91
2.34
2.9
2.4
—
—
—
0
0
23
119
1.96
2.32
3.7
1.6
0.75
0.85
nmol/l
0.31
17
101
24
128
1.90
2.23
1.5
1.6
—
—
—
0
0
566
5307
1.29
2.21
7.0
5.4
41.14
39.47
mmol/mol
3.13
520
4949
22
115
1.94
2.17
1.6
1.6
—
—
—
0
0
627
5971
1.34
2.10
26.2
14.9
139.27
139.66
mmol/l
3.75
611
5804
28
161
1.77
2.08
1.3
1.4
189.95
304.78
ug/g
1.79
15
95
13
56
2.35
2.05
1.4
1.1
—
—
—
0
0
261
2261
1.24
2.04
2.2
2.0
—
—
—
0
0
183
1524
1.27
2.02
5.4
3.7
0.00
0.01
estimate
0.69
54
522
628
5990
1.33
2.02
26.2
15.1
3.97
3.97
mmol/l
0.24
610
5818
40
604
0.64
2.00
1.4
1.4
—
—
—
0
0
9
32
2.83
2.00
3.3
2.3
—
—
—
0
0
23
126
1.85
2.00
2.1
1.6
21113.24
14060.55
e6/l
0.27
17
99
16
77
2.10
1.98
4.6
5.1
368.75
365.82
umol/l
0.03
16
66
79
585
1.39
1.97
1.4
1.4
—
—
—
0
0
33
203
1.65
1.95
4.6
1.4
—
—
—
0
0
33
204
1.65
1.92
4.5
1.4
—
—
—
0
0
101
782
1.34
1.92
1.4
1.3
507.83
520.49
titre
0.03
23
162
21
367
0.56
1.90
1.3
1.4
—
—
—
0
0
33
205
1.64
1.89
4.6
1.4
—
—
—
0
0
8
28
2.88
1.86
1.4
1.6
—
—
—
0
0
32
198
1.64
1.86
2.1
2.1
17577.25
2938.26
u/l
—
10
85
30
183
1.67
1.84
2.1
2.4
10.54
10.70
g/l
0.05
22
167
6
17
3.55
1.84
1.2
1.4
2.50
1.39
%
—
6
12
6
17
3.55
1.84
1.3
1.4
28.83
46.82
%
—
6
11
31
191
1.65
1.84
1.8
1.4
—
—
—
0
0
56
396
1.45
1.82
5.9
2.4
5.13
5.98
e9/l
0.21
40
328
18
94
1.94
1.81
1.7
1.6
—
—
—
0
0
30
185
1.65
1.78
4.1
8.2
1.26
1.33
mmol/l
0.20
25
167
24
139
1.75
1.77
2.7
2.2
136.56
122.42
ug/min
0.07
15
79
14
67
2.11
1.77
4.9
2.5
—
—
—
0
0
133
1084
1.28
1.74
2.2
1.8
—
—
—
0
0
83
634
1.35
1.73
3.9
2.8
7.05
8.92
umol/l
0.73
69
560
22
125
1.78
1.73
3.5
3.9
—
—
—
0
0
5
13
3.86
1.71
2.0
1.7
—
—
—
0
0
60
435
1.41
1.71
2.6
3.4
213.78
193.29
ng/l
0.16
51
400
31
195
1.62
1.71
1.5
1.3
157.00
249.51
miu/ml
—
9
94
11
48
2.31
1.71
1.4
1.4
1.94
1.21
promille
—
5
41
18
97
1.88
1.67
1.4
1.2
7.44
8.77
u/ml
—
9
44
13
62
2.12
1.66
5.5
2.1
32.00
33.77
pg
0.81
13
62
22
127
1.75
1.65
1.2
1.3
—
—
—
0
0
133
1600
0.79
1.63
3.9
3.1
—
—
—
0
0
13
63
2.08
1.60
1.6
1.2
—
—
—
0
0
15
77
1.97
1.60
4.1
2.9
—
—
—
0
0
84
652
1.33
1.59
1.4
1.3
—
—
—
0
0
8
33
2.44
1.54
5.8
20.5
993.25
1489.52
nmol/l
—
8
33
32
209
1.56
1.54
3.3
3.0
22.11
21.50
s
0.31
27
191
6
21
2.87
1.51
2.3
2.9
44016.67
35190.71
ug/l
—
6
21
5
128
0.39
1.50
1.6
1.6
—
—
—
0
0
10
45
2.24
1.47
2.3
2.9
38.45
36.13
%
—
10
45
48
346
1.41
1.45
1.7
1.6
0.91
1.58
g/l
2.32
42
323
176
1513
1.21
1.44
1.7
1.7
1.53
1.41
mmol/l
1.01
160
1290
136
1140
1.24
1.41
3.7
2.7
543.91
557.89
mosm/kgh2o
0.31
117
967
10
46
2.19
1.40
1.8
5.0
11.75
11.36
%
—
10
46
129
1077
1.24
1.39
5.0
3.5
42.88
521.42
ng/l
5.30
100
818
10
47
2.14
1.34
1.1
1.1
—
—
—
0
0
13
68
1.93
1.34
1.1
1.2
—
—
—
0
0
19
113
1.70
1.33
13.1
3.9
2.73
2.58
mmol/l
0.12
14
74
18
106
1.72
1.30
2.2
2.4
18.26
16.35
%
—
8
54
18
106
1.72
1.30
3.6
3.3
3.20
4.18
e9/l
1.91
18
106
20
122
1.66
1.28
2.1
1.4
254.08
246.43
u/ml
0.04
13
71
16
92
1.76
1.26
5.6
1.3
67.00
63.72
mmol/l
0.06
11
81
23
147
1.58
1.24
1.4
1.2
3.42
13.46
u/ml
—
6
24
30
204
1.49
1.24
4.9
1.4
—
—
—
0
0
18
109
1.67
1.19
1.8
1.2
—
—
—
0
0
21
321
0.64
1.19
1.9
1.7
—
—
—
0
0
11
57
1.94
1.17
2.6
2.6
—
—
—
0
0
55
423
1.32
1.15
11.2
4.0
1.23
1.23
mmol/l
0.16
50
364
5
20
2.51
1.15
1.0
1.1
1656.60
1581.10
miu/ml
—
5
20
8
152
0.52
1.15
1.3
1.1
—
—
—
0
0
100
1193
0.81
1.14
3.2
3.0
0.64
0.79
ug/l
1.89
64
772
18
111
1.64
1.13
4.0
3.6
51.78
57.17
%
0.86
18
111
10
51
1.97
1.11
1.6
1.1
1.08
1.43
nmol/l
—
10
46
67
534
1.28
1.10
3.4
4.5
8.25
31.03
ug/l
0.82
49
442
15
89
1.70
1.08
1.9
2.8
—
—
—
0
0
60
474
1.29
1.06
1.5
1.4
—
—
—
0
0
427
4023
1.15
1.06
4.1
3.6
—
—
—
0
0
7
33
2.13
1.05
5.3
12.8
559.14
804.21
nmol/l
—
7
33
5
22
2.28
1.03
2.0
1.1
—
—
—
0
0
5
22
2.28
1.03
1.2
1.1
—
—
—
0
0
632
6138
1.21
1.03
20.2
12.4
—
—
—
0
0
145
1265
1.18
1.02
5.7
3.7
1.02
1.02
kg/l
0.53
19
180
10
53
1.90
1.01
1.3
2.7
0.70
1.07
e9/l
—
10
43
15
91
1.66
1.01
1.5
1.5
—
—
—
0
0
7
35
2.01
1.00
2.3
1.9
—
—
—
0
0
23
156
1.49
0.99
1.3
2.5
37.15
38.12
g/l
0.23
15
141
639
6218
1.21
0.98
15.0
9.9
27.06
26.65
u/l
0.21
618
6004
115
986
1.20
0.98
1.4
1.3
43.15
35.08
iu/ml
0.24
36
310
0
30
0.00
0.97
0.0
8.8
—
—
—
0
0
7
36
1.95
0.97
1.4
1.5
—
—
—
0
0
10
54
1.86
0.97
1.0
1.6
—
—
—
0
0
6
27
2.23
0.93
3.3
2.1
56.83
46.90
umol/l
—
6
20
22
153
1.45
0.86
3.2
3.0
—
—
—
0
0
17
114
1.50
0.80
1.0
1.6
—
—
—
0
0
10
58
1.73
0.80
2.0
1.3
—
—
—
0
0
16
106
1.52
0.79
4.1
3.6
—
—
—
0
0
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
6
33
1.82
0.79
14.7
10.8
0.58
0.64
mmol/l
—
6
33
11
66
1.68
0.79
1.5
1.5
—
—
—
0
0
8
48
1.67
0.79
1.3
1.4
—
—
—
0
0
13
82
1.60
0.78
1.3
1.2
21.69
17.59
u/l
0.23
13
72
9
55
1.64
0.73
2.1
1.2
—
—
—
0
0
5
25
2.01
0.72
4.0
3.6
—
—
—
0
0
5
26
1.93
0.70
6.6
4.4
—
—
—
0
0
5
26
1.93
0.70
1.4
2.1
13.68
9.45
nmol/l
—
5
20
14
93
1.52
0.70
8.7
3.2
—
—
—
0
0
7
42
1.67
0.68
1.4
2.9
0.18
0.19
e9/l
—
7
33
5
28
1.79
0.66
1.0
1.4
147.00
180.77
mmol/24h
—
5
28
66
561
1.19
0.66
1.6
1.6
—
—
—
0
0
33
260
1.28
0.65
3.1
3.3
—
—
—
0
0
5
30
1.67
0.61
1.0
1.3
6.46
6.95
ug/l
—
5
25
5
30
1.67
0.61
1.8
1.4
—
—
—
0
0
5
30
1.67
0.61
3.2
1.8
10.14
9.02
mmol/l
—
5
30
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
8
52
1.54
0.59
1.4
1.1
—
—
—
0
0
6
35
1.72
0.57
1.2
1.1
—
—
—
0
0
9
62
1.46
0.53
1.2
1.3
—
—
—
0
0
9
132
0.68
0.52
1.3
1.2
—
—
—
0
0
21
270
0.77
0.52
1.2
1.1
—
—
—
0
0
187
2005
0.91
0.51
4.7
4.9
2.49
2.71
ug/l
0.16
157
1807
6
41
1.47
0.50
1.2
1.0
—
—
—
0
0
10
67
1.50
0.50
2.3
2.6
—
—
—
0
0
81
721
1.14
0.49
1.3
1.3
—
—
—
0
0
10
142
0.70
0.46
4.1
4.4
—
—
—
0
0
564
5519
1.09
0.46
4.6
3.8
1.37
1.29
mmol/l
1.63
512
5086
8
121
0.66
0.45
1.9
1.3
—
—
—
0
0
20
156
1.29
0.45
1.1
1.2
—
—
—
0
0
7
50
1.40
0.45
2.4
3.3
—
—
—
0
0
10
69
1.46
0.44
1.1
1.0
1.93
4.75
u/ml
—
5
22
5
31
1.62
0.43
1.4
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
9
69
1.31
0.37
1.4
1.9
—
—
—
0
0
25
207
1.22
0.37
1.3
1.6
—
—
—
0
0
581
5713
1.08
0.36
5.0
4.2
1.38
1.45
mmol/l
4.44
527
5289
60
668
0.89
0.35
1.7
1.6
—
—
—
0
0
155
1646
0.93
0.35
1.4
1.4
—
—
—
0
0
9
122
0.73
0.35
1.8
1.3
—
—
—
0
0
9
124
0.72
0.35
1.9
1.4
—
—
—
0
0
34
292
1.17
0.35
1.1
1.1
—
137.10
—
0
10
593
5841
1.08
0.33
5.4
4.7
2.61
2.76
mmol/l
3.67
542
5406
41
360
1.15
0.33
3.1
2.6
—
—
—
0
0
493
5027
0.94
0.31
29.4
16.8
330.92
333.01
g/l
5.33
488
4990
571
5622
1.07
0.31
5.5
4.3
6.17
5.90
mmol/l
3.30
521
5140
30
261
1.16
0.28
1.5
1.4
32.72
28.02
iu/l
0.33
25
219
26
224
1.17
0.27
1.1
1.1
—
—
—
0
0
8
66
1.21
0.26
1.1
1.3
—
—
nmol/l
—
0
0
11
86
1.28
0.26
1.9
1.4
—
—
—
0
0
5
75
0.66
0.26
26.6
2.0
13.22
13.23
%
—
5
75
15
123
1.22
0.25
1.9
2.2
143.33
131.85
g/l
—
9
92
582
5746
1.06
0.25
5.1
4.3
4.44
4.65
mmol/l
5.34
530
5349
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
4.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
15.70
—
0
9
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
2.3
2.8
—
—
—
0
0
41
375
1.10
0.19
1.3
1.2
—
—
—
0
0
6
51
1.18
0.19
1.0
1.2
—
—
—
0
0
11
90
1.23
0.19
1.1
1.0
0.61
6.41
u/ml
—
5
44
11
91
1.21
0.17
2.4
1.8
—
—
—
0
0
5
69
0.72
0.17
1.2
1.3
—
—
—
0
0
11
129
0.85
0.15
1.2
1.3
—
—
—
0
0
119
1147
1.04
0.14
1.6
1.7
477.91
18040056.45
pmol/l
1.04
98
959
12
103
1.17
0.14
1.0
1.1
—
12.00
—
0
6
29
268
1.09
0.12
3.0
2.3
—
—
—
0
0
509
5133
0.97
0.11
26.0
15.6
15.00
14.80
%
0.37
504
5049
40
424
0.94
0.11
1.4
1.2
43.01
162.03
iu/ml
4.83
15
172
19
173
1.10
0.10
1.8
1.4
10.56
9.72
u/l
0.07
14
141
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
6
55
1.09
0.09
1.2
1.4
—
—
—
0
0
6
56
1.07
0.08
1.3
1.7
—
—
—
0
0
5
63
0.79
0.08
1.4
1.1
—
—
—
0
0
7
81
0.86
0.07
1.3
1.1
—
—
—
0
0
7
85
0.82
0.07
1.1
1.2
—
—
—
0
0
16
173
0.92
0.06
17.7
9.1
—
—
—
0
0
8
94
0.85
0.06
2.9
3.1
—
—
—
0
0
48
492
0.97
0.03
5.2
3.5
—
—
—
0
0
656
6552
1.01
0.01
33.8
19.3
39.44
41.08
%
1.47
619
6125
58
587
0.99
0.01
1.4
1.5
—
—
—
0
0
656
6553
1.01
0.01
33.3
19.2
257.68
249.26
e9/l
2.18
639
6375
48
475
1.01
0.00
2.6
2.1
12.51
12.93
nmol/l
0.15
43
430
10
98
1.02
0.00
1.0
1.1
—
—
—
0
0
10
98
1.02
0.00
1.0
1.1
—
—
—
0
0
656
6555
1.01
0.00
33.3
19.1
90.93
90.83
fl
0.22
644
6455
656
6556
1.01
0.00
33.3
19.1
30.13
30.30
pg
1.54
644
6454
656
6557
1.00
0.00
33.4
19.2
4.42
4.52
e12/l
5.26
639
6361
656
6557
1.00
0.00
33.4
19.2
7.16
6.68
e9/l
6.46
637
6355
656
6559
1.00
0.00
33.9
19.3
132.31
136.08
g/l
7.79
645
6457
5
51
0.98
0.00
1.6
1.1
—
—
—
0
0
6
66
0.91
0.00
1.2
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.6
—
0.32
—
0
9
0
8
0.00
-0.00
0.0
1.3
—
1.85
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
85.60
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
77.20
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
61
0.98
-0.00
3.3
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_PYODERMA and mortality.

Females

Parameter HR [95% CI] p-value
L12_PYODERMA 2.971 [2.44, 3.62] < 0.001
Birth year 0.996 [0.99, 1.01] 0.409

During the follow-up period (1.1.1998 — 31.12.2019), 506 out of 2065 females with L12_PYODERMA died.

Males

Parameter HR [95% CI] p-value
L12_PYODERMA 3.025 [2.54, 3.61] < 0.001
Birth year 0.989 [0.98, 1.0] 0.028

During the follow-up period (1.1.1998 — 31.12.2019), 688 out of 2431 males with L12_PYODERMA died.

Mortality risk

Mortality risk for people of age

years, who have L12_PYODERMA.

N-year risk Females Males
1 0.308% 0.658%
5 1.762% 3.384%
10 4.729% 8.653%
15 8.484% 16.462%
20 14.789% 26.195%

Relationships between endpoints

Index endpoint: L12_PYODERMA – Pyoderma

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data