Birth injury to peripheral nervous system

P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM

peripheral nervous system disease: A disease involving the peripheral nervous system.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P14 Cause of death: ICD-10 — P14 2 out of 7 registries used, show all original rules.	109
4. Check minimum number of events None	109
5. Include endpoints None	109
6. Filter based on genotype QC (FinnGen only)	109

Control definitions (FinnGen only)

Control exclude: P16_BIRTH_TRAUMA

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P1[0-5]
Name in latin: Laesio intranatalis systematis nervosi peripherici

NAME	P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM
CONTROL_EXCLUDE	P16_BIRTH_TRAUMA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P14
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P14
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Birth injury to peripheral nervous system based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	3211	1629	1580
Only index persons	2307	1193	1114
Unadjusted period prevalence (%)
Whole population	0.05	0.05	0.04
Only index persons	0.04	0.04	0.04
Median age at first event (years)
Whole population	0.07	0.06	0.05
Only index persons	0.08	0.09	0.07

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	109	70	39
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	7.48	6.66	8.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
98: Matched controls
980

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

P14.0

ICD-10 Finland

Erb paralysis due to birth injury

+∞

135.6

7676A

ICD-9 Finland

Birth trauma, Injury to brachial plexus

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

5.35

3.45

1.0

1.2

—

(3027315) Oxygen [Partial pressure] in Blood

8.98

3.30

4.3

8.4

7.98

9.60

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

8.98

3.30

4.8

8.4

4.78

5.54

kpa

—

(1616796) Gas panel - Central venous blood

6.98

2.90

4.2

8.1

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

530

1.97

2.84

6.2

5.9

79.68

81.85

u/l

0.14

498

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.02

2.56

1.4

1.1

—

(3019309) Folate [Moles/volume] in Red Blood Cells

2.51

2.56

1.9

1.5

1234.00

1030.86

nmol/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

744

2.20

2.55

4.2

4.1

1.67

1.82

mu/l

0.94

688

(3013650) Neutrophils [#/volume] in Blood by Automated count

484

1.78

2.24

5.5

8.6

4.00

4.07

e9/l

0.10

426

(3041096) Erythrocytes [Presence] in Urine by Automated

222

1.85

2.19

2.4

2.5

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

3.11

1.98

1.4

1.2

3.23

2.95

ug/l

—

(3013707) Erythrocyte sedimentation rate by Westergren method

555

1.66

1.75

3.4

3.7

7.86

7.62

mm/h

0.07

514

(3006315) Basophils [#/volume] in Blood

421

1.62

1.67

4.7

6.5

0.04

e9/l

0.16

375

(3041806) Other cells [#/volume] in Blood by Manual count

3.44

1.54

2.0

1.5

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

2.60

1.48

1.4

1.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

644

1.59

1.40

3.5

14.86

14.48

pmol/l

0.81

572

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

285

1.57

1.39

2.8

3.0

—

(3027945) Reticulocytes/100 erythrocytes in Blood

2.09

1.39

2.4

4.7

1.53

1.54

0.01

(3032080) INR in Blood by Coagulation assay

197

1.64

1.39

6.6

6.1

1.16

1.11

inr

0.20

(1761868) Lipid panel - Serum or Plasma

259

1.58

1.37

1.7

1.9

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

668

1.59

1.35

3.0

2.9

5.36

5.49

mmol/l

0.64

611

(3022145) Colonoscopy Study observation

2.05

1.33

1.9

1.4

—

(3023520) Reticulocytes [#/volume] in Blood

2.14

1.30

3.7

3.0

57.10

70.98

e9/l

—

(3021589) Normoblasts [#/volume] in Blood

392

1.51

1.28

7.7

8.0

0.00

e9/l

0.00

312

(3001604) Monocytes [#/volume] in Blood

421

1.50

1.27

4.9

6.5

0.50

0.55

e9/l

1.75

375

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

186

1.60

1.22

1.9

2.5

13.88

21.31

ng/l

0.61

(3003694) ABO and Rh group [Type] in Blood

286

1.50

1.16

1.7

1.8

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.57

1.16

3.0

1.3

—

(36304419) Bacteria [Presence] in Urine

198

1.56

1.13

3.5

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

114

1.69

1.11

2.4

2.7

16188.26

4481.67

u/l

—

(40761536) Microorganisms panel - Urine sediment

1.89

1.09

4.0

3.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

123

1.66

1.09

1.2

1.3

13.68

23.11

iu/ml

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

684

1.49

1.07

3.0

2.71

2.79

mmol/l

0.39

645

(3030467) Casts [#/volume] in Urine by Automated count

192

1.54

1.06

3.7

3.6

0.36

0.18

e6/l

0.65

149

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

553

1.43

1.02

3.6

3.5

36.88

36.75

mmol/mol

0.04

522

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.99

0.0

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.21

0.93

1.0

1.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

683

1.43

0.91

3.2

2.9

4.42

4.58

mmol/l

0.87

645

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.13

0.91

1.0

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.13

0.91

1.0

1.2

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

770

1.47

0.88

11.0

10.4

139.55

139.50

mmol/l

0.08

747

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

1.84

0.86

1.6

1.3

—

(3009261) Glucose [Presence] in Urine by Test strip

378

1.38

0.84

2.9

3.1

0.00

estimate

0.00

(3014007) Fractional oxyhemoglobin in Arterial blood

1.92

0.83

10.2

13.0

96.08

94.87

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.66

0.82

3.3

2.4

2.55

2.58

g/l

0.06

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.80

0.0

1.8

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

231

1.41

0.80

3.4

3.6

—

(3009508) Creatinine [Moles/volume] in Urine

195

1.44

0.79

5.0

3.0

10.17

8.80

mmol/l

0.24

178

(3023103) Potassium [Moles/volume] in Serum or Plasma

776

1.43

0.78

11.2

10.4

3.98

3.90

mmol/l

1.95

750

(3021601) Nitrite [Presence] in Urine by Test strip

372

1.36

0.78

4.0

4.2

0.00

estimate

0.00

(3002582) Erythrocytes [#/volume] in Urine

216

1.40

0.73

3.7

3.4

215.22

46.57

e6/l

0.60

168

(3035350) Ketones [Presence] in Urine by Test strip

376

1.34

0.72

3.0

3.1

0.00

estimate

—

(42870588) Differential panel, method unspecified - Blood

272

1.36

0.72

5.5

6.9

—

(3029937) Albumin [Presence] in Urine by Test strip

199

1.40

0.71

3.3

3.4

0.00

0.01

estimate

0.49

(3028707) Methadone [Presence] in Urine by Screen method

1.70

0.71

3.1

2.2

—

(3011288) Drugs identified in Urine by Screen method

1.56

0.71

3.3

2.0

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.82

0.67

2.2

1.2

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

104

1.51

0.67

3.1

1.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

547

1.31

0.66

3.5

4.0

—

(3031040) Bacteria [#/volume] in Urine by Automated count

519

1.30

0.64

3.7

4.1

—

178.60

—

(3044889) 12 lead EKG panel

431

1.30

0.63

3.1

2.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

195

1.37

0.61

3.8

4.0

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.62

0.61

7.0

11.0

23.66

25.11

mmol/l

—

(3013512) EKG study

125

1.43

0.58

2.6

2.8

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

179

1.36

0.57

1.7

1.8

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.52

0.57

4.3

1.9

—

(40758558) Short blood count panel - Blood

207

1.34

0.56

3.5

6.7

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.54

0.56

1.6

5.5

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.52

0.55

8.3

10.7

106.67

105.66

mmol/l

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.49

0.55

1.7

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

1.44

0.53

4.6

9.1

1.68

1.48

mmol/l

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

1.53

0.52

1.7

1.9

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.59

0.50

1.4

1.5

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

375

1.24

0.46

2.6

1.8

—

(3016879) Cocaine [Presence] in Urine

122

1.37

0.45

2.9

1.8

—

(3018095) Leukocytes [#/volume] in Urine

261

1.26

0.45

3.9

63.34

67.23

e6/l

0.03

174

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

686

1.25

0.45

9.8

7.4

97.82

103.58

ml/min/173m2

1.53

513

(3042936) Bacteria identified in Isolate by Culture

1.43

0.44

2.4

2.3

—

(40768797) Stomach Pathology biopsy report

1.47

0.43

1.4

1.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.59

0.43

2.0

1.3

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.59

0.43

12.0

13.0

0.86

1.57

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.59

0.43

1.4

1.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.39

0.42

2.0

1.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

179

1.29

0.41

1.7

1.4

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.1

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.41

0.0

1.1

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.41

0.0

1.0

—

12.00

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.40

0.0

1.1

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.40

0.0

1.4

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.35

0.39

1.2

1.4

—

(3007164) IgA [Mass/volume] in Serum or Plasma

263

0.80

0.38

1.5

1.4

1.80

1.91

g/l

0.21

156

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

883

1.27

0.34

10.7

9.8

16.54

20.00

mg/l

0.49

648

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

194

1.24

0.33

2.1

1.6

107.03

97.11

pmol/l

0.69

105

(40761511) CBC panel - Blood by Automated count

917

1.28

0.31

10.1

8.5

—

(3027008) Opiates [Presence] in Urine

130

1.27

0.31

2.9

1.8

—

(3028300) Cannabinoids [Presence] in Urine

130

1.27

0.31

3.0

1.8

—

(3000764) Benzodiazepines [Presence] in Urine

130

1.27

0.31

3.0

1.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

177

1.23

0.30

1.8

1.5

—

(3007853) Bacteria identified in Skin by Aerobe culture

103

1.30

0.30

1.5

1.6

—

(3009542) Hematocrit [Volume Fraction] of Blood

876

1.24

0.29

11.8

11.4

40.57

40.55

0.01

745

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

341

1.18

0.29

4.6

4.3

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.35

0.29

2.7

1.3

—

(3005719) IgG [Mass/volume] in Serum or Plasma

0.68

0.27

2.0

2.3

10.62

10.41

g/l

—

(3023368) Bacteria identified in Blood by Culture

133

1.24

0.26

4.7

4.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

168

0.81

0.25

3.6

3.3

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

210

0.83

0.25

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.26

0.23

2.6

1.6

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.23

0.22

2.6

1.3

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.5

—

2.91

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.5

—

(4094501)

0.00

0.21

0.0

1.0

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.5

—

6.80

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.21

0.0

2.5

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(1175426) CD3 cells/100 lymphocytes in Blood

0.00

0.21

0.0

3.7

—

72.80

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(4062490)

0.00

0.21

0.0

1.0

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.00

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

9.22

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.21

0.0

3.7

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

42.47

—

(3006245) CD3-CD19+ cells/100 cells in Blood

0.00

0.21

0.0

3.2

—

11.40

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.21

0.0

1.2

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3022621) pH of Urine by Test strip

1.29

0.21

2.3

1.8

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

14.9

—

1213.46

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3027944) Amphetamines [Presence] in Urine

128

1.20

0.19

3.1

1.8

—

(3019225) pH of Specimen

1.16

0.19

3.7

6.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

100

1.22

0.19

1.3

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

142

0.83

0.19

1.3

1.6

—

(3018418) pH of Serum or Plasma

148

1.18

0.18

7.4

3.6

7.41

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

216

1.14

0.17

2.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

373

1.11

0.17

2.3

2.1

—

(21494755) Public health laboratory ask at order entry panel

111

1.19

0.16

1.2

—

(3000494) Fungus identified in Specimen by Culture

0.78

0.16

1.3

1.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.18

0.16

1.8

1.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.14

0.15

1.8

1.5

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.79

0.15

1.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.21

0.14

1.3

1.4

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

103

1.19

0.14

2.4

3.0

9.67

530.19

ng/l

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

268

1.11

0.14

8.8

10.0

1.22

mmol/l

0.15

246

(3044640) Blood type and Crossmatch panel - Blood

210

1.12

0.13

1.9

2.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

309

1.10

0.12

3.0

2.4

—

(36660697) Celiac disease serology panel - Serum

115

1.15

0.11

1.1

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.17

0.10

4.8

2.1

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

302

1.08

0.10

1.4

0.58

1.52

u/ml

—

(3008898) HLA-B27 [Presence]

1.14

0.09

1.0

1.1

—

(3026008) Bacteria identified in Urine by Culture

215

0.91

0.08

2.4

2.6

—

(3000492) Spirometry study

1.15

0.08

1.2

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

334

1.07

0.08

3.2

2.6

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.80

0.08

1.5

1.6

—

(40768804) Tissue Pathology biopsy report

265

1.08

0.08

1.7

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.88

0.07

1.5

—

(3015736) pH of Urine

296

1.07

0.06

2.7

2.9

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

104

0.85

0.06

1.8

2.0

—

(3048689) Calprotectin [Mass/mass] in Stool

168

1.09

0.06

4.7

2.8

146.17

81.31

ug/g

0.58

129

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

878

1.07

0.06

4.4

4.1

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

292

0.94

0.05

2.1

1.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

159

0.93

0.03

2.5

2.6

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.10

0.03

1.3

1.5

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

152

1.06

0.02

1.3

1.6

1.07

1.32

mmol/l

1.00

132

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

294

1.03

0.00

9.5

10.5

1.22

mmol/l

0.13

263

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

117

1.03

0.00

1.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

251

0.99

0.00

1.8

—

(3005033) Fetal Nuchal fold Thickness US

0.98

0.00

1.6

1.5

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.98

0.00

1.6

1.5

—

(3000991) Gas panel - Venous blood

1.00

0.00

10.4

8.5

—

(3002256) Pathology report gross observation

1.00

0.00

1.0

1.1

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.1

—

(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.8

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

0.0

1.4

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

0.00

0.0

1.0

—

17.32

—

(40761872) Peanut recombinant (rAra h) 2 IgE Ab [Units/volume] in Serum

0.00

0.0

1.1

—

8.40

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

0.0

2.8

—

(3013336) Amino acids [Identifier] in Serum or Plasma

0.00

0.0

1.2

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

0.92

0.00

3.7

6.8

0.82

0.81

mmol/l

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.4

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.0

2.4

—

(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood

0.00

0.0

3.3

—

27.00

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.0

1.0

—

87.80

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.92

0.00

6.4

9.9

24.28

24.62

mmol/l

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

1.6

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.1

—

(3005880) Parainfluenza virus 3 Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

0.0

1.3

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.2

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.3

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.93

0.00

1.5

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(4211845)

0.00

0.0

1.0

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.0

1.8

—

52.00

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.0

1.3

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.1

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.93

0.00

1.5

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.0

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.93

0.00

1.5

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.95

0.00

1.0

1.6

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.96

0.00

1.6

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1866.14

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

49.60

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

3.0

—

168.78

—

(3004959) Base excess in Arterial cord blood by calculation

0.00

0.0

1.0

—

(3010375) cycloSPORINE [Mass/volume] in Blood

0.00

0.0

12.2

—

181.60

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

4.1

—

0.00

—

(3022313) Gas panel - Capillary blood

0.90

0.00

5.0

9.9

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.4

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

4.1

—

0.00

—

(3025941) Bacteria identified in Stool by Culture

0.96

0.00

1.2

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3006598) pH of Arterial cord blood

0.00

0.0

1.0

—

(3001964) Herpes simplex virus Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.98

0.00

1.0

1.1

—

(3011841) English Walnut IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

0.06

—

(3021578) Parainfluenza virus 2 Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3010464) Parainfluenza virus 1 Ag [Presence] in Specimen

0.00

0.0

1.0

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.93

0.00

1.5

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.2

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.0

1.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

0.0

4.4

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM – Birth injury to peripheral nervous system

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Birth injury to peripheral nervous system

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints