Birth injury to peripheral nervous system

P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM

peripheral nervous system disease: A disease involving the peripheral nervous system.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P14 Hospital discharge: ICD-9 — 7676A\|7677A Cause of death: ICD-10 — P14 Cause of death: ICD-9 — 7676A\|7677A 2 out of 7 registries used, show all original rules.	124
4. Check minimum number of events None	124
5. Include endpoints None	124
6. Filter based on genotype QC (FinnGen only)	121

Control definitions (FinnGen only)

Control exclude: P16_BIRTH_TRAUMA

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P1[0-5]
Name in latin: Laesio intranatalis systematis nervosi peripherici

NAME	P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM
CONTROL_EXCLUDE	P16_BIRTH_TRAUMA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P14
HD_ICD_9	7676A\|7677A
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P14
COD_ICD_9	7676A\|7677A
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Birth injury to peripheral nervous system based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	121	82	39
Unadjusted period prevalence (%)	0.03	0.03	0.02
Median age at first event (years)	1.62	1.83	1.18

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
124: Matched controls
1240

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

P14.0

ICD-10 Finland

Erb paralysis due to birth injury

+∞

142.8

108

7676A

ICD-9 Finland

Birth trauma, Injury to brachial plexus

+∞

22.6

NBU20

NOMESCO Finland

Removal of internal fixation device from shoulder or upper arm

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

4.33

2.94

1.0

1.1

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

601

1.87

2.78

5.7

77.81

80.28

u/l

0.19

563

(3013290) Carbon dioxide [Partial pressure] in Blood

6.24

2.73

4.8

7.1

4.78

5.25

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

6.24

2.73

4.3

7.1

7.98

9.76

kpa

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

102

858

2.06

2.48

4.2

1.66

1.80

mu/l

0.93

800

(1616796) Gas panel - Central venous blood

5.19

2.43

4.2

6.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

268

1.73

2.02

2.5

2.6

—

(3019309) Folate [Moles/volume] in Red Blood Cells

2.11

1.91

1.9

1.6

1164.10

1059.22

nmol/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

546

1.59

1.77

5.4

8.1

4.01

4.08

e9/l

0.10

477

(3003694) ABO and Rh group [Type] in Blood

352

1.59

1.67

1.6

1.9

—

(3022217) INR in Platelet poor plasma by Coagulation assay

246

1.65

1.66

8.3

7.6

1.15

1.12

inr

0.10

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

740

1.59

1.54

3.5

3.6

14.90

14.40

pmol/l

1.38

663

(3015235) Bicarbonate [Moles/volume] in Capillary blood

3.21

1.45

2.4

3.6

25.50

23.43

mmol/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.18

1.43

1.4

1.1

—

(3013707) Erythrocyte sedimentation rate by Westergren method

635

1.51

1.39

3.3

3.6

7.71

7.78

mm/h

0.02

588

(3041806) Other cells [#/volume] in Blood by Manual count

3.02

1.37

2.0

1.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

771

1.55

1.36

2.9

5.38

5.47

mmol/l

0.43

705

(3022145) Colonoscopy Study observation

1.99

1.34

1.8

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

207

1.59

1.32

1.8

2.5

13.88

20.39

ng/l

0.55

(3006315) Basophils [#/volume] in Blood

473

1.47

1.30

4.7

6.2

0.04

e9/l

0.19

417

(3021589) Normoblasts [#/volume] in Blood

445

1.47

1.29

7.6

0.00

e9/l

-0.00

356

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

643

1.47

1.25

3.5

3.4

36.54

36.62

mmol/mol

0.02

606

(3013826) Glucose [Moles/volume] in Serum or Plasma

458

1.45

1.22

4.3

5.7

5.96

6.18

mmol/l

0.54

400

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

2.18

1.21

1.4

1.2

3.23

3.55

ug/l

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

338

1.47

1.18

2.9

3.0

—

(3001604) Monocytes [#/volume] in Blood

472

1.43

1.14

4.8

6.2

0.52

0.55

e9/l

0.39

417

(3023520) Reticulocytes [#/volume] in Blood

1.90

1.01

3.7

2.9

57.10

70.50

e9/l

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.82

1.00

2.4

4.3

1.53

1.56

0.02

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

784

1.42

0.97

3.0

2.9

4.39

4.57

mmol/l

1.16

738

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.94

0.95

1.4

1.2

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

105

0.45

0.93

1.0

1.7

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

408

1.38

0.93

2.5

2.8

—

(3022948) Iron [Moles/volume] in Serum or Plasma

103

1.64

0.93

2.9

2.6

11.47

14.24

umol/l

0.93

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.12

0.90

1.0

1.2

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

2.12

0.90

2.2

1.2

—

(36304419) Bacteria [Presence] in Urine

225

1.44

0.90

3.6

3.4

—

(1761868) Lipid panel - Serum or Plasma

307

1.39

0.90

1.7

1.8

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.05

0.88

1.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.05

0.88

1.0

1.2

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

879

1.41

0.82

10.0

139.60

139.50

mmol/l

0.21

854

(3014007) Fractional oxyhemoglobin in Arterial blood

1.86

0.80

10.2

12.8

96.08

94.90

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.13

0.75

3.0

1.3

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

885

1.38

0.73

10.2

9.9

3.98

3.90

mmol/l

1.91

855

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

261

1.36

0.73

3.3

3.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

145

1.45

0.71

1.2

13.68

22.45

iu/ml

—

(3037467) Urinalysis macro (dipstick) panel - Urine

639

1.30

0.71

3.6

4.1

—

(3030467) Casts [#/volume] in Urine by Automated count

217

1.38

0.70

3.8

3.5

0.33

0.22

e6/l

0.37

166

(3009261) Glucose [Presence] in Urine by Test strip

444

1.29

0.68

2.9

3.2

0.00

estimate

-0.00

(40768443) Skin Pathology biopsy report

1.82

0.67

1.0

1.2

—

(3044889) 12 lead EKG panel

485

1.28

0.65

2.9

2.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

196

0.68

0.64

3.6

3.2

—

(3021601) Nitrite [Presence] in Urine by Test strip

438

1.28

0.63

4.0

4.3

0.00

estimate

-0.00

(3007164) IgA [Mass/volume] in Serum or Plasma

294

0.73

0.63

1.5

1.4

1.80

1.92

g/l

0.24

176

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.61

0.0

1.5

—

6.19

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.60

0.0

1.1

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.60

0.0

1.0

—

9.38

—

(3029937) Albumin [Presence] in Urine by Test strip

232

1.33

0.60

3.3

3.4

0.00

0.01

estimate

0.49

(21494755) Public health laboratory ask at order entry panel

124

1.43

0.59

1.2

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.48

0.59

3.1

2.4

2.62

2.53

g/l

0.20

(40761536) Microorganisms panel - Urine sediment

1.53

0.59

4.0

3.7

—

(3009508) Creatinine [Moles/volume] in Urine

223

1.33

0.59

4.9

2.9

10.35

8.77

mmol/l

0.32

206

(3035350) Ketones [Presence] in Urine by Test strip

441

1.27

0.59

3.0

3.1

0.00

estimate

-0.00

(3031040) Bacteria [#/volume] in Urine by Automated count

611

1.25

0.56

3.6

4.3

—

178.60

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

144

1.38

0.55

2.4

2.8

16188.26

4249.96

u/l

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

118

1.41

0.53

2.9

1.9

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.51

0.48

7.0

10.6

23.66

25.06

mmol/l

—

(40760892) CBC W Ordered Manual Differential panel - Blood

442

1.22

0.46

6.0

6.5

—

(3002582) Erythrocytes [#/volume] in Urine

241

1.27

0.46

3.8

3.4

205.80

52.16

e6/l

0.56

185

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.49

0.46

7.6

9.7

107.50

105.35

mmol/l

—

(40758558) Short blood count panel - Blood

232

1.27

0.45

3.4

6.3

—

(3044640) Blood type and Crossmatch panel - Blood

251

1.26

0.45

1.8

2.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.45

0.45

1.6

5.4

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

1.49

0.44

1.6

1.3

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

105

1.38

0.43

3.9

1.9

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.47

0.43

1.6

1.7

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.59

0.42

12.0

13.0

0.86

1.57

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

216

1.26

0.41

1.7

1.8

—

(3011288) Drugs identified in Urine by Screen method

106

1.36

0.41

3.3

2.1

—

(3028707) Methadone [Presence] in Urine by Screen method

1.44

0.40

3.1

2.2

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.40

0.0

1.1

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.45

0.40

1.4

1.9

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.39

0.0

1.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

361

1.20

0.38

2.9

2.4

—

(3013512) EKG study

144

1.29

0.38

2.6

2.8

—

(3016879) Cocaine [Presence] in Urine

135

1.30

0.37

2.8

1.8

—

(40768797) Stomach Pathology biopsy report

1.39

0.37

1.4

1.2

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

1.31

0.37

4.6

8.5

1.68

1.36

mmol/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

200

1.25

0.37

2.0

1.4

—

(3042936) Bacteria identified in Isolate by Culture

1.35

0.37

2.4

2.2

—

(3005719) IgG [Mass/volume] in Serum or Plasma

0.63

0.37

2.0

2.2

10.62

10.33

g/l

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

1.45

0.36

1.7

1.9

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

104

1000

1.25

0.34

10.2

9.6

16.04

19.71

mg/l

0.60

740

(3000494) Fungus identified in Specimen by Culture

0.67

0.34

1.3

1.6

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.71

0.32

1.0

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

796

1.17

0.31

9.0

7.1

99.21

103.60

ml/min/173m2

1.19

599

(3003327) Ova and parasites identified in Stool by Light microscopy

1.31

0.31

1.4

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

397

1.17

0.31

3.2

2.6

—

(3022621) pH of Urine by Test strip

1.29

0.30

2.1

2.0

—

(40761511) CBC panel - Blood by Automated count

108

1046

1.25

0.30

9.7

8.5

—

(40768804) Tissue Pathology biopsy report

301

1.18

0.30

1.6

—

(3018095) Leukocytes [#/volume] in Urine

302

1.17

0.29

3.9

3.8

58.27

63.88

e6/l

0.04

196

(3023368) Bacteria identified in Blood by Culture

150

1.23

0.28

4.3

4.0

—

(3009542) Hematocrit [Volume Fraction] of Blood

118

1155

1.45

0.24

14.9

14.0

40.42

40.43

0.00

112

1104

(46235355) HIV 1 and 2 tests - Meaningful Use set

453

1.14

0.24

2.5

2.1

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.33

0.23

2.0

1.5

—

(3002032) Base excess in Venous blood by calculation

1.27

0.23

3.3

5.6

0.47

1.47

mmol/l

—

(3027008) Opiates [Presence] in Urine

145

1.20

0.22

2.8

1.8

—

(3000764) Benzodiazepines [Presence] in Urine

145

1.20

0.22

2.9

1.8

—

(3028300) Cannabinoids [Presence] in Urine

145

1.20

0.22

2.9

1.8

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.5

—

43.15

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.21

0.0

2.5

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.5

—

0.00

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.21

0.0

1.0

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.5

—

9.26

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

(3006245) CD3-CD19+ cells/100 cells in Blood

0.00

0.21

0.0

3.2

—

11.40

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.21

0.0

3.7

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.00

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.8

—

0.00

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.21

0.0

1.1

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

0.21

0.0

1.1

—

(3027831) CD3-CD16+CD56+ (Natural killer) cells/100 cells in Blood

0.00

0.21

0.0

3.6

—

10.00

—

(1175426) CD3 cells/100 lymphocytes in Blood

0.00

0.21

0.0

3.7

—

72.80

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.3

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.3

—

6.79

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.3

—

2.78

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.3

—

3.34

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.3

—

2.67

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(4062490) Immunoglobulin typing, IgG

0.00

0.21

0.0

1.1

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

2.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.7

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

15.0

—

1277.86

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

223

1.15

0.20

1.6

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

103

1003

1.16

0.19

4.4

4.1

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.23

0.18

2.5

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.24

0.17

1.7

1.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

120

1.19

0.17

7.1

3.6

5.20

28.16

mg/mmol

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.11

0.15

1.2

1.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

112

1.18

0.15

1.5

1.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

112

1.18

0.15

2.0

1.4

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.78

0.15

1.6

1.7

—

(3048689) Calprotectin [Mass/mass] in Stool

189

1.13

0.15

4.1

2.7

134.00

80.56

ug/g

0.60

143

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

434

1.10

0.15

2.5

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

316

1.10

0.14

1.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.19

0.13

1.7

1.6

—

(3027944) Amphetamines [Presence] in Urine

143

1.14

0.12

3.0

1.8

—

(3019150) Specific gravity of Urine by Refractometry

229

0.90

0.12

2.6

2.8

1.02

1.01

kg/l

—

(36660697) Celiac disease serology panel - Serum

125

1.14

0.10

1.1

—

(3026008) Bacteria identified in Urine by Culture

258

0.91

0.10

2.3

2.5

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.17

0.10

1.2

1.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.17

0.10

2.6

1.5

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

116

1.13

0.09

2.3

2.8

9.67

501.98

ng/l

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.09

0.09

2.6

1.4

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.15

0.09

1.3

1.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

234

1.09

0.09

2.0

1.6

109.68

96.14

pmol/l

1.20

127

(3025941) Bacteria identified in Stool by Culture

0.83

0.08

1.2

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.12

0.08

1.1

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

174

0.91

0.08

1.3

1.6

1.07

1.33

mmol/l

1.09

149

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.84

0.08

1.7

1.5

—

(3005033) Fetal Nuchal fold Thickness US

0.84

0.08

1.7

1.5

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.82

0.08

1.7

1.6

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

108

1.12

0.07

1.3

—

(3002256) Pathology report gross observation

0.88

0.07

1.0

1.1

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

334

0.94

0.06

9.0

9.6

1.22

mmol/l

0.05

296

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

240

0.95

0.04

1.7

1.6

—

(3018418) pH of Serum or Plasma

172

1.05

0.02

7.0

3.4

7.41

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

188

0.95

0.02

1.4

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

263

1.03

0.01

1.9

2.0

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

343

1.03

0.01

1.4

0.59

1.39

u/ml

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

106

0.94

0.01

3.4

6.3

0.82

0.81

mmol/l

—

(3000492) Spirometry study

1.05

0.00

1.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

109

1.01

0.00

1.3

1.5

—

(3050129) First trimester maternal screen panel - Serum or Plasma

121

0.99

0.00

1.4

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

129

1.01

0.00

1.6

1.8

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

131

0.99

0.00

1.5

2.0

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

355

1.02

0.00

2.1

1.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

192

0.99

0.00

2.4

—

(3022313) Gas panel - Capillary blood

0.84

0.00

5.0

9.3

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

1.01

0.00

1.4

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

1.01

0.00

1.4

1.5

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

0.84

0.00

6.4

9.2

24.28

24.59

mmol/l

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

1.01

0.00

1.4

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

1.01

0.00

1.4

1.5

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

3.0

—

168.78

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

87.80

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

49.60

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

2.7

—

357.57

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

4.0

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

140.60

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.6

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.7

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.90

-0.00

1.4

1.6

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.4

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.2

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.98

-0.00

4.8

2.4

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.7

—

1.82

—

(3016038) Potassium [Moles/volume] in Urine

0.00

-0.00

0.0

1.8

—

52.00

—

(3010375) cycloSPORINE [Mass/volume] in Blood

0.00

-0.00

0.0

12.2

—

181.60

—

(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(40761872) Peanut recombinant (rAra h) 2 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

8.40

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.6

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

0.45

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.1

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.6

—

(3030862) Granulocytes [#/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3001964) Herpes simplex virus Ag [Presence] in Specimen

0.00

-0.00

0.0

1.0

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3000991) Gas panel - Venous blood

0.95

-0.00

10.4

8.2

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

1.8

—

(3008898) HLA-B27 [Presence]

0.98

-0.00

1.0

1.1

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

-0.00

0.0

2.8

—

40.83

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

8.01

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.8

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.8

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

0.00

-0.00

0.0

1.0

—

17.32

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3004959) Base excess in Arterial cord blood by calculation

0.00

-0.00

0.0

1.0

—

(3019225) pH of Specimen

0.98

-0.00

3.7

5.5

—

(3011841) English Walnut IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

0.06

—

(3007449) CD3+CD8+ (T8 suppressor) cells/100 cells in Blood

0.00

-0.00

0.0

3.3

—

27.00

—

(42868499) Enterovirus IgG Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.2

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

1.6

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3023419) Bacteria identified in Sputum by Culture

0.00

-0.00

0.0

3.2

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.7

—

(3006598) pH of Arterial cord blood

0.00

-0.00

0.0

1.0

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1693.50

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.3

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

0.97

-0.00

4.5

7.0

24.17

23.55

mmol/l

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3013336) Amino acids [Identifier] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.00

-0.00

1.3

1.6

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM – Birth injury to peripheral nervous system

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Birth injury to peripheral nervous system

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Birth injury to peripheral nervous system (P16_BIRTHINJY_PERIP_NERVOUS_SYSTEM)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints