otitis externa: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
540 |
4. Check minimum number of eventsNone |
540 |
5. Include endpointsNone |
540 |
6. Filter based on genotype QC (FinnGen only) |
514 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H60
- Name in latin
- Abscessus auris externae
Similar endpoints
↥List of similar endpoints to
Abscess of external ear
based on the number of shared cases.
Similar with more cases:
- Otitis externa
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5026 | 2233 | 2766 |
| Only index persons | 4591 | 2057 | 2534 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.06 | 0.08 |
| Only index persons | 0.09 | 0.08 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 34.04 | 36.08 | 32.27 |
| Only index persons | 33.71 | 36.09 | 31.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 514 | 273 | 241 |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | 0.11 |
| Median age at first event (years) | 41.99 | 39.64 | 44.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 540
- Matched controls
- 5400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H60.0
ICD-10 Finland
Abscess of external ear
7733.8
307.7
487
5
H60.3
ICD-10 Finland
Other infective otitis externa
44.7
167.7
102
28
H60.9
ICD-10 Finland
Otitis externa, unspecified
13.7
151.1
164
167
H60.8
ICD-10 Finland
Other otitis externa
27.1
120.0
85
37
H60.1
ICD-10 Finland
Cellulitis of external ear
35.8
72.3
46
14
38000
ICD-8 Finland
Otitis externa, Abscessus auris externae
+∞
50.8
48
*
UDC00
NOMESCO Finland
Ear microscopy
6.2
49.2
93
174
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
9.4
41.2
51
59
H60
ICD-10 Finland
Otitis externa
5.5
33.3
70
143
H66.9
ICD-10 Finland
Otitis media, unspecified
4.7
32.1
82
198
H01
ICPC
Ear pain/earache
3.5
26.6
105
346
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
8.1
25.3
35
46
H70
ICPC
Otitis externa
8.2
22.8
31
40
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.2
22.2
104
378
H65.3
ICD-10 Finland
Chronic mucoid otitis media
7.3
21.4
32
46
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
114.5
20.7
22
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.5
20.6
78
248
J01MA02
ATC
ciprofloxacin; systemic
2.3
19.4
229
1304
J01DA01
ATC
[U] cefalexin
2.3
17.6
363
2560
H29
ICPC
Ear symptom/complaint other
3.1
17.6
83
301
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.7
17.3
107
450
A46
ICD-10 Finland
Erysipelas
2.8
16.9
95
380
J01DB01
ATC
cefalexin; oral
3.0
16.3
474
3821
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
7.0
15.0
23
34
J01FF01
ATC
clindamycin; systemic
2.2
14.8
167
915
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
17.6
14.4
22
13
TDA90
NOMESCO Finland
Removal wax from ear
14.1
13.8
23
17
DAA00
NOMESCO Finland
Incision of auricle
+∞
13.6
13
*
H61.8
ICD-10 Finland
Other specified disorders of external ear
35.0
13.6
17
5
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
10.4
13.1
25
25
SPAT1301
SPAT
No procedures
2.0
13.0
180
1059
S02CA02
ATC
flumetasone and antiinfectives; otic
3.6
12.8
43
126
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
12.7
308
2189
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
11.6
173
1036
H61.2
ICD-10 Finland
Impacted cerumen
3.5
11.6
41
124
SPAT1260
SPAT
Consultation of another employee
2.3
11.5
105
522
H04
ICPC
Ear discharge
4.9
11.3
25
53
N02AX02
ATC
tramadol; systemic, rectal
1.9
11.2
227
1505
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.4
10.5
81
374
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
10.4
85
402
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
10.3
226
1523
SPAT1262
SPAT
Handing over of treatment supplies
2.2
10.3
94
466
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
10.3
123
678
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.7
10.3
23
31
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
10.0
211
1403
H71
ICD-10 Finland
Cholesteatoma of middle ear
10.9
9.8
18
17
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
9.7
54
213
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
9.5
76
356
DC1AD
NOMESCO Finland
Temporalbone CT
12.6
9.4
16
13
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
7.2
9.1
21
30
H65.0
ICD-10 Finland
Acute serous otitis media
7.2
9.1
21
30
H02AB06
ATC
prednisolone; systemic
1.7
9.0
244
1731
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
4.5
8.9
22
51
J01MA12
ATC
levofloxacin; systemic
2.1
8.9
100
536
R10.0
ICD-10 Finland
Acute abdomen
4.2
8.8
23
56
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
50.8
8.7
10
*
L72.1
ICD-10 Finland
Trichilemmal cyst
2.8
8.6
44
166
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
8.5
134
807
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.4
8.2
60
270
J01AA02
ATC
doxycycline; systemic
1.8
8.2
393
3236
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
17.5
8.1
12
7
H70.1
ICD-10 Finland
Chronic mastoiditis
33.9
8.1
10
*
R03AC02
ATC
salbutamol; inhalant
1.7
8.1
299
2288
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
22.4
8.0
11
5
J46
ICD-10 Finland
Status asthmaticus
4.4
8.0
20
47
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.7
8.0
43
167
SPAT1263
SPAT
Sampling
1.7
8.0
226
1611
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
7.9
110
636
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
7.9
139
866
M79.6
ICD-10 Finland
Pain in limb
1.7
7.8
220
1562
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.0
7.8
22
57
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.6
7.7
46
188
N03AX16
ATC
[U] pregabalin
1.9
7.7
121
727
H65.2
ICD-10 Finland
Chronic serous otitis media
8.2
7.6
16
20
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.9
7.6
117
698
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
3.1
7.5
31
104
R03BA02
ATC
budesonide; inhalant
1.9
7.3
103
597
N06AX16
ATC
venlafaxine; oral
2.0
7.3
88
484
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
4.6
7.2
17
38
SPAT1310
SPAT
Counselling related to known health issue
1.7
7.2
168
1130
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.2
134
846
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
7.1
73
377
U05
ICPC
Urination problems other
3.0
7.0
31
108
P01AB01
ATC
metronidazole; oral, rectal
1.7
7.0
204
1452
L73.2
ICD-10 Finland
Hidradenitis suppurativa
6.0
7.0
18
31
D07XC01
ATC
betamethasone; topical
2.1
6.8
66
335
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
6.8
64
321
J01CA04
ATC
amoxicillin; systemic
1.8
6.7
446
3890
R42
ICD-10 Finland
Dizziness and giddiness
1.8
6.7
104
619
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.3
6.6
25
79
EBA00
NOMESCO Finland
Extraction of tooth
1.6
6.6
201
1441
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.2
6.6
26
85
SPAT1252
SPAT
Overall medication plan or its review
2.7
6.5
34
130
A02BC02
ATC
pantoprazole; systemic
1.6
6.5
328
2651
R02
ICPC
Shortness of breath/dyspnoea
2.1
6.5
64
326
R33
ICD-10 Finland
Retention of urine
2.5
6.4
40
167
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
6.4
168
1158
J01FA06
ATC
roxithromycin; oral
1.6
6.4
201
1449
N05BA01
ATC
diazepam; systemic, rectal
2.0
6.4
71
377
S10
ICPC
Boil/carbuncle
2.5
6.4
39
161
C09CA06
ATC
candesartan; oral
1.8
6.4
117
733
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
6.3
53
253
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.9
6.3
30
109
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
9.4
6.3
12
13
H61.0
ICD-10 Finland
Perichondritis of external ear
+∞
6.3
6
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
6.2
229
1715
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
6.2
254
1949
L17
ICPC
Foot/toe symptom/complaint
1.7
6.1
145
973
Z3231
NOMESCO Finland
Registered nurse
1.7
6.1
140
931
SPAT1153
SPAT
Removal of sutures
1.7
6.1
146
984
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.0
99
599
WX002
NOMESCO Finland
Sedation and analgesia
1.8
6.0
93
553
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
231
1599
1.78
9.44
6.5
4.9
35.99
36.27
g/l
0.31
206
1507
244
1719
1.77
9.36
14.9
11.5
1.23
1.18
inr
0.34
79
521
189
1238
1.81
9.27
4.2
3.1
8.30
8.07
mmol/l
0.22
161
1060
314
2384
1.76
9.21
6.6
4.8
6.77
6.61
mmol/l
0.59
301
2185
171
1120
1.77
8.22
5.2
3.8
19.47
10.08
mg/mmol
0.77
118
723
90
486
2.02
7.83
9.2
6.0
1.08
1.04
mmol/l
0.59
85
455
19
48
4.07
6.94
1.4
1.3
—
—
—
0
0
207
1482
1.64
6.93
5.2
3.3
32.52
37.55
ng/l
0.34
115
936
276
2127
1.61
6.81
6.1
6.4
12.18
11.18
umol/l
0.34
260
2024
374
3113
1.66
6.65
4.3
3.9
12.50
10.42
mm/h
1.82
345
2894
166
1135
1.67
6.59
2.5
2.1
161.44
274.46
u/l
1.00
155
1073
145
957
1.70
6.57
2.6
2.0
2.66
3.06
mg/l
1.62
129
813
310
2470
1.60
6.55
9.1
9.1
4.35
4.06
e9/l
1.35
283
2163
488
4396
2.14
6.55
19.9
12.4
21.97
22.62
mg/l
0.18
404
3408
180
1285
1.60
5.91
4.0
2.6
54.70
60.79
u/l
0.77
160
1207
386
3286
1.61
5.80
4.3
3.9
14.61
14.63
pmol/l
0.06
349
3020
374
3180
1.57
5.46
8.5
7.4
81.48
76.98
u/l
1.01
352
2990
48
234
2.15
5.46
1.7
1.4
—
—
—
0
0
200
1485
1.55
5.45
2.0
1.8
101.19
95.13
pmol/l
1.10
103
769
73
416
1.87
5.39
7.8
8.7
0.58
1.04
mmol/l
0.29
60
333
149
1041
1.60
5.26
2.9
2.6
2887.17
5268.35
umol/l
0.38
135
926
479
4376
1.84
4.84
21.6
13.7
139.53
139.66
mmol/l
0.53
472
4261
152
1086
1.56
4.82
4.0
2.8
0.75
0.40
e6/l
0.50
119
801
139
973
1.58
4.82
1.9
1.8
1.02
1.10
mg/l
0.23
101
727
480
4390
1.84
4.80
21.6
13.8
3.97
3.96
mmol/l
0.49
472
4266
119
804
1.62
4.79
3.6
2.4
6.44
6.00
e6/l
0.09
104
726
55
297
1.95
4.77
3.6
2.3
4.75
7.39
ug/l
0.73
48
270
219
1698
1.49
4.71
8.6
6.1
1.20
1.21
mmol/l
1.34
204
1561
43
214
2.10
4.66
2.1
2.4
6408.11
3225.20
u/l
0.30
15
92
94
605
1.67
4.57
3.4
2.3
13.37
13.92
umol/l
0.30
88
564
121
832
1.59
4.51
1.6
1.5
20.00
20.78
nmol/l
0.22
98
717
235
1860
1.47
4.50
10.2
6.7
1.20
1.21
mmol/l
1.14
203
1590
186
1406
1.49
4.49
4.4
2.9
—
—
—
0
0
76
468
1.73
4.34
8.1
6.2
103.62
104.31
mmol/l
0.45
76
468
147
1065
1.52
4.32
1.4
1.3
2.29
2.08
u/ml
0.07
32
312
21
78
2.76
4.30
2.7
2.0
129.38
130.67
g/l
0.10
16
58
81
510
1.69
4.27
3.4
2.3
23.47
23.89
%
0.10
71
448
92
600
1.64
4.24
2.2
1.9
—
—
—
0
0
91
594
1.64
4.18
3.3
2.1
30.42
29.56
s
0.75
85
577
255
2089
1.42
3.88
4.4
3.3
0.00
0.00
estimate
0.50
62
418
67
411
1.72
3.88
2.3
1.8
—
—
—
0
0
255
2091
1.42
3.85
6.1
4.5
0.00
0.00
estimate
0.50
60
401
107
744
1.55
3.76
1.3
1.3
10.25
34.04
iu/ml
6.40
27
247
93
628
1.58
3.71
2.7
2.8
2.43
2.43
mmol/l
0.03
78
544
93
629
1.58
3.68
2.0
1.7
1166.35
1142.52
nmol/l
0.09
68
475
437
3981
1.51
3.50
5.2
4.5
1.84
1.85
mu/l
0.05
395
3711
255
2116
1.39
3.48
4.5
3.3
0.00
0.00
estimate
-0.00
59
381
164
1262
1.43
3.46
3.7
3.2
2.35
2.35
mmol/l
0.04
140
1125
206
1651
1.40
3.45
2.7
2.2
73.73
73.75
nmol/l
0.00
187
1495
57
352
1.69
3.24
6.5
3.8
0.81
1.90
mmol/l
1.42
49
287
445
4094
1.49
3.15
16.4
10.9
88.01
87.34
ml/min/173m2
0.21
382
3345
61
387
1.65
3.14
3.8
2.4
37.45
153.92
u/l
0.46
55
329
23
105
2.24
3.13
1.9
1.6
—
—
—
0
0
101
722
1.49
3.10
1.3
1.3
1.11
10.77
u/ml
3.86
34
301
50
304
1.71
3.02
2.0
2.4
70.50
73.13
ml/min/173m2
0.13
20
124
64
418
1.60
2.94
2.3
1.8
—
—
—
0
0
88
618
1.51
2.94
3.1
2.7
2.39
2.10
e6/l
0.14
52
319
59
380
1.62
2.87
3.5
2.9
—
—
—
0
0
99
718
1.46
2.82
5.0
3.7
128.85
318.94
ng/l
0.79
75
502
420
3852
1.41
2.75
7.3
5.2
41.34
39.17
mmol/mol
3.02
391
3626
17
72
2.41
2.75
1.0
1.1
4.31
2.56
u/ml
—
10
38
237
1997
1.33
2.73
2.7
2.5
—
—
—
0
0
199
1635
1.34
2.72
4.6
3.3
—
—
—
0
0
67
453
1.55
2.67
11.1
6.5
—
—
—
0
0
7
15
4.71
2.60
1.1
1.3
—
—
—
0
0
27
144
1.92
2.51
1.7
2.2
1.41
1.37
g/l
0.08
21
129
7
16
4.42
2.48
1.1
1.3
—
—
—
0
0
232
1973
1.31
2.43
3.6
2.8
136.28
110.17
ug/l
0.75
215
1837
129
1007
1.37
2.42
1.9
1.6
—
—
—
0
0
344
3090
1.31
2.38
3.7
3.1
54.83
44.51
u/l
1.17
324
2928
41
255
1.66
2.32
6.5
3.9
114.82
79.31
ng/l
1.22
34
232
14
59
2.41
2.31
2.1
1.3
—
—
—
0
0
358
3241
1.31
2.29
3.3
3.4
—
—
—
0
0
8
23
3.51
2.27
1.1
1.1
75.38
98.77
u/l
—
8
23
8
23
3.51
2.27
1.1
1.1
13.38
31.82
u/l
—
8
23
139
1110
1.34
2.24
4.8
3.5
0.00
0.01
estimate
1.08
60
393
38
235
1.66
2.20
4.2
3.5
1.89
1.61
mmol/l
0.22
28
174
43
275
1.61
2.19
1.7
1.6
—
—
—
0
0
50
332
1.56
2.18
2.5
2.3
0.22
0.22
g/l
0.11
45
310
16
74
2.20
2.16
1.3
1.6
—
—
—
0
0
7
20
3.53
2.06
1.1
1.3
—
—
—
0
0
25
140
1.82
2.04
1.5
1.8
—
—
—
0
0
27
156
1.77
2.00
2.1
1.7
—
—
—
0
0
460
4349
1.39
1.99
5.3
4.4
2.72
2.82
mmol/l
1.33
427
4067
121
963
1.33
1.99
3.7
3.2
1451.46
1037.76
ng/l
0.59
100
801
21
112
1.91
1.99
1.2
1.4
338.07
307.40
ug/g
0.30
14
65
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
105
1.94
1.98
5.2
3.0
0.32
0.34
u/ml
0.06
11
58
27
158
1.75
1.93
1.8
1.8
—
—
—
0
0
87
663
1.37
1.89
3.2
2.5
1.61
0.90
e6/l
0.74
52
360
18
93
1.97
1.87
1.3
1.2
—
—
—
0
0
133
1087
1.30
1.80
1.7
1.6
1.43
1.41
mmol/l
0.11
111
935
12
54
2.25
1.75
1.3
1.5
—
—
—
0
0
7
24
2.94
1.72
1.1
1.3
—
—
—
0
0
86
665
1.35
1.71
1.8
1.8
1.55
1.46
%
0.47
77
602
452
4292
1.33
1.64
5.0
4.0
4.55
4.69
mmol/l
2.07
423
4037
92
725
1.32
1.62
2.4
1.9
—
—
—
0
0
438
4148
1.30
1.57
5.0
4.0
6.10
5.85
mmol/l
1.94
394
3827
175
1502
1.24
1.57
3.4
3.5
52.76
31.35
u/l
0.50
161
1435
25
153
1.66
1.56
1.6
2.0
—
—
—
0
0
449
4268
1.31
1.55
4.9
4.0
1.40
1.44
mmol/l
1.46
419
3998
21
123
1.74
1.53
2.2
2.8
—
—
—
0
0
98
786
1.30
1.53
1.7
1.7
477.96
432.94
pmol/l
0.93
76
685
13
65
2.02
1.50
1.3
1.4
—
—
—
0
0
486
4679
1.39
1.49
12.0
9.5
28.63
27.52
u/l
0.59
471
4542
513
4994
1.54
1.40
27.1
18.0
4.50
4.56
e12/l
1.99
504
4867
513
4997
1.53
1.36
27.2
18.2
135.55
137.36
g/l
1.94
508
4932
512
4989
1.51
1.31
27.3
18.1
254.75
251.81
e9/l
0.44
506
4875
35
491
0.69
1.30
1.6
1.7
—
—
—
0
0
512
4990
1.50
1.30
27.2
18.1
39.95
41.66
%
1.05
474
4708
30
203
1.51
1.27
1.5
1.5
—
—
—
0
0
8
35
2.30
1.27
1.0
1.1
—
—
—
0
0
97
798
1.26
1.25
2.6
2.1
—
—
—
0
0
6
25
2.42
1.24
2.0
3.4
—
—
—
0
0
15
85
1.79
1.24
3.7
3.7
27.73
34.86
umol/l
1.47
15
79
118
1000
1.23
1.17
2.4
2.1
—
—
—
0
0
431
4116
1.23
1.17
4.5
3.6
1.38
1.29
mmol/l
1.21
401
3839
8
39
2.07
1.15
1.0
1.2
—
—
—
0
0
46
346
1.36
1.14
1.3
1.2
214.90
159.11
iu/ml
—
10
149
18
111
1.64
1.13
3.2
2.2
124.57
55.02
ug/min
0.44
12
60
15
88
1.72
1.12
1.1
1.2
—
1.03
—
0
7
62
491
1.30
1.09
3.0
2.8
9.20
8.20
umol/l
0.13
53
429
5
21
2.39
1.09
1.2
1.2
—
—
—
0
0
5
22
2.28
1.03
2.0
3.0
36680.00
38200.00
ug/l
—
5
22
13
75
1.75
1.03
1.3
1.6
—
—
—
0
0
112
960
1.21
1.00
4.1
3.4
1.02
1.02
kg/l
0.17
16
135
9
52
1.74
0.92
1.2
1.3
—
—
—
0
0
6
28
2.16
0.91
1.0
1.3
3.85
1.87
mmol/l
—
6
28
8
42
1.92
0.89
1.0
1.0
—
—
—
0
0
10
56
1.80
0.88
1.2
1.6
—
—
—
0
0
13
81
1.62
0.82
1.1
1.2
—
—
—
0
0
21
147
1.45
0.81
1.3
1.5
1.35
1.17
g/l
1.48
21
139
26
190
1.39
0.80
1.3
1.4
283.74
255.66
miu/ml
—
9
95
144
1288
1.16
0.80
4.7
4.3
2.53
2.16
ug/l
0.23
130
1169
16
106
1.52
0.79
1.3
1.3
186.43
240.06
u/ml
0.41
11
66
0
25
0.00
0.79
0.0
3.1
—
—
—
0
0
15
98
1.55
0.79
1.7
4.3
122.41
110.49
mg/l
—
9
83
29
218
1.35
0.77
1.6
1.4
408.78
288.12
mu/l
0.61
23
196
6
34
1.77
0.76
1.3
1.6
—
—
—
0
0
6
34
1.77
0.76
1.0
1.2
—
68.00
—
0
5
44
352
1.27
0.76
1.7
1.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
24
2.09
0.74
1.2
1.3
—
—
—
0
0
7
38
1.85
0.73
1.3
1.2
—
—
—
0
0
7
38
1.85
0.73
1.3
1.3
—
—
—
0
0
20
142
1.42
0.73
1.4
1.5
0.26
0.23
g/l
0.55
20
134
25
185
1.37
0.73
2.2
1.4
12.32
9.06
u/l
0.49
20
154
14
92
1.54
0.73
1.1
1.2
—
—
—
0
0
7
40
1.76
0.71
1.0
1.8
—
—
—
0
0
25
187
1.35
0.69
4.8
2.8
0.66
0.67
%
0.08
25
187
7
42
1.68
0.68
1.1
1.5
—
—
—
0
0
5
27
1.86
0.68
1.0
1.1
—
—
—
0
0
5
27
1.86
0.68
1.2
1.1
154.40
119.20
iu/ml
—
5
27
15
103
1.47
0.65
1.1
1.2
—
—
—
0
0
7
44
1.60
0.65
2.7
3.3
—
—
—
0
0
14
95
1.49
0.64
1.7
4.2
—
1.20
—
0
14
16
112
1.44
0.64
1.3
1.3
—
—
—
0
0
21
155
1.37
0.64
1.4
1.4
—
—
—
0
0
16
113
1.43
0.61
1.2
1.2
—
3.20
—
0
13
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
25
192
1.32
0.60
4.8
2.9
1.29
1.41
%
0.17
25
192
34
273
1.26
0.59
2.9
3.9
4.57
4.65
pmol/l
0.11
29
241
10
64
1.57
0.59
1.2
1.1
1.54
1.41
g/l
—
10
58
14
98
1.44
0.57
1.7
4.3
52.01
33.80
mg/l
—
8
84
15
109
1.39
0.51
7.8
4.1
1.59
1.38
mg/l
0.58
15
99
7
45
1.56
0.49
1.0
1.1
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
—
—
—
0
0
23
285
0.80
0.44
1.2
1.2
—
—
—
0
0
14
104
1.36
0.43
1.6
1.4
113.13
102.83
u/ml
—
6
24
8
57
1.41
0.42
1.1
1.5
—
—
—
0
0
5
33
1.52
0.41
3.4
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
23.73
—
0
17
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
17
215
0.78
0.39
2.0
1.9
—
—
—
0
0
20
160
1.26
0.39
1.5
1.6
—
—
—
0
0
9
68
1.33
0.37
1.0
1.1
—
—
—
0
0
14
180
0.77
0.37
1.4
1.4
—
—
—
0
0
14
180
0.77
0.37
1.4
1.4
—
—
—
0
0
10
72
1.40
0.37
1.2
1.7
—
—
—
0
0
11
81
1.37
0.36
1.5
1.5
—
—
—
0
0
14
179
0.78
0.36
1.4
1.4
—
—
—
0
0
14
179
0.78
0.36
1.4
1.4
—
—
—
0
0
50
446
1.13
0.33
2.0
1.9
—
—
—
0
0
16
128
1.26
0.32
1.3
1.1
—
—
—
0
0
11
84
1.32
0.30
1.7
1.5
—
—
—
0
0
11
84
1.32
0.30
1.1
1.0
2.68
2.05
u/ml
—
5
42
52
469
1.12
0.29
4.4
4.0
32.31
30.89
%
0.42
35
331
7
57
1.23
0.29
7.9
2.8
105.29
105.42
mmol/l
—
7
57
16
194
0.82
0.28
1.4
1.5
—
—
—
0
0
9
74
1.22
0.25
3.8
4.1
—
2779.30
—
0
10
29
256
1.14
0.23
1.1
1.0
—
—
—
0
0
11
88
1.26
0.22
2.6
1.3
—
—
—
0
0
11
88
1.26
0.22
2.6
1.3
—
—
—
0
0
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
5
41
1.22
0.22
29.4
18.4
1723.40
1450.93
nmol/l
—
5
41
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
43.90
—
0
10
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
15
127
1.19
0.19
1.3
1.3
—
—
—
0
0
20
226
0.88
0.17
1.3
1.4
—
—
—
0
0
17
148
1.15
0.17
1.8
1.9
—
—
—
0
0
10
120
0.83
0.16
1.3
1.5
—
—
—
0
0
8
70
1.14
0.16
1.1
1.1
—
—
—
0
0
8
72
1.11
0.16
5.8
5.8
422.75
372.22
umol/l
—
8
65
6
76
0.79
0.15
1.3
1.1
—
—
—
0
0
10
119
0.84
0.15
1.8
1.9
4.84
5.52
iu/l
—
5
42
9
80
1.13
0.15
8.1
4.3
62.11
56.89
%
—
9
80
13
150
0.86
0.15
1.2
1.1
—
—
—
0
0
30
326
0.92
0.14
1.4
1.5
—
—
—
0
0
8
98
0.81
0.14
1.3
1.4
—
—
—
0
0
13
148
0.88
0.12
1.2
1.1
—
—
—
0
0
12
104
1.16
0.12
1.3
1.6
773.42
404.91
mg/l
0.66
12
96
41
385
1.07
0.12
3.0
2.3
10.82
13.60
nmol/l
1.13
30
357
77
740
1.05
0.11
1.4
1.4
—
—
—
0
0
5
44
1.14
0.10
2.0
1.1
—
—
—
0
0
5
47
1.06
0.09
1.2
1.8
—
—
—
0
0
105
1023
1.03
0.09
3.6
4.0
23.58
20.90
%
0.75
47
428
19
175
1.09
0.08
1.3
1.3
—
—
—
0
0
13
143
0.91
0.07
1.5
1.5
—
—
—
0
0
9
102
0.88
0.06
1.6
1.2
—
—
—
0
0
21
220
0.95
0.03
1.6
2.4
23.07
31.99
u/ml
0.44
21
210
35
361
0.97
0.03
2.7
4.3
4.42
41.65
ug/l
1.01
26
299
73
743
0.98
0.03
2.7
2.7
0.76
0.70
ug/l
0.22
48
443
10
92
1.09
0.03
2.3
1.9
—
—
—
0
0
11
102
1.08
0.03
1.4
1.6
—
—
—
0
0
10
93
1.08
0.02
1.3
1.5
3.98
3.68
mmol/l
—
10
83
10
94
1.07
0.01
2.7
1.8
—
—
—
0
0
10
105
0.95
0.00
1.4
1.6
—
—
—
0
0
13
135
0.96
0.00
1.8
1.7
—
—
—
0
0
13
129
1.01
0.00
1.2
2.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
54
0.93
-0.00
1.2
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
76
0.92
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
80
1.00
-0.00
1.4
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXT_ABSC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_ABSC | 1.518 [1.23, 1.88] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.427 |
During the follow-up period (1.1.1998 — 31.12.2019), 227 out of 1895 females with H8_EXT_ABSC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_ABSC | 1.552 [1.3, 1.85] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 326 out of 2212 males with H8_EXT_ABSC died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXT_ABSC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.136% | 0.284% |
| 5 | 0.798% | 1.831% |
| 10 | 2.06% | 4.494% |
| 15 | 4.252% | 8.106% |
| 20 | 7.656% | 13.681% |
Relationships between endpoints
↥Index endpoint: H8_EXT_ABSC – Abscess of external ear
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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