otitis externa: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
526 |
4. Check minimum number of eventsNone |
526 |
5. Include endpointsNone |
526 |
6. Filter based on genotype QC (FinnGen only) |
526 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H60
- Name in latin
- Abscessus auris externae
Similar endpoints
↥List of similar endpoints to
Abscess of external ear
based on the number of shared cases.
Similar with more cases:
- Otitis externa
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5026 | 2233 | 2766 |
| Only index persons | 4591 | 2057 | 2534 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.06 | 0.08 |
| Only index persons | 0.09 | 0.08 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 34.04 | 36.08 | 32.27 |
| Only index persons | 33.71 | 36.09 | 31.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 526 | 274 | 252 |
| Unadjusted period prevalence (%) | 0.10 | 0.09 | 0.11 |
| Median age at first event (years) | 41.96 | 39.52 | 44.62 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 477
- Matched controls
- 4771
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H60.0
ICD-10 Finland
Abscess of external ear
10140.7
323.0
427
5
H60.9
ICD-10 Finland
Otitis externa, unspecified
15.5
80.0
139
123
H60.3
ICD-10 Finland
Other infective otitis externa
65.3
75.1
86
16
H60.8
ICD-10 Finland
Other otitis externa
45.8
60.6
74
19
38000
ICD-8 Finland
Otitis externa, Abscessus auris externae
+∞
47.7
45
*
H60.1
ICD-10 Finland
Cellulitis of external ear
35.2
30.5
39
12
UDC00
NOMESCO Finland
Ear microscopy
6.7
29.9
81
142
H66.9
ICD-10 Finland
Otitis media, unspecified
6.1
23.6
67
124
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
10.2
21.6
43
46
J01DB01
ATC
cefalexin; oral
3.1
18.7
414
3252
H66.0
ICD-10 Finland
Acute suppurative otitis media
4.7
17.7
62
146
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
186.6
17.6
18
*
J01DA01
ATC
[U] cefalexin; systemic
2.3
16.9
322
2245
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.3
15.9
89
314
H60
ICD-10 Finland
Otitis externa
5.3
15.8
49
101
H01
ICPC
Ear pain/earache
3.3
15.5
84
287
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
29.7
15.3
20
7
H65.3
ICD-10 Finland
Chronic mucoid otitis media
9.4
15.2
31
35
H29
ICPC
Ear symptom/complaint other
3.7
15.2
69
207
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
7.4
14.4
34
49
A46
ICD-10 Finland
Erysipelas
3.2
13.4
76
269
J01FF01
ATC
clindamycin; systemic
2.3
13.4
150
791
J01MA02
ATC
ciprofloxacin; systemic
2.1
13.1
195
1168
D07AB02
ATC
hydrocortisone butyrate; topical
2.3
13.0
147
775
DAA00
NOMESCO Finland
Incision of auricle
133.4
12.5
13
*
SPAT1260
SPAT
Consultation of another employee
2.6
11.8
96
426
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.5
11.4
94
419
TDA90
NOMESCO Finland
Removal wax from ear
12.3
10.9
19
16
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
10.9
193
1217
S02CA02
ATC
flumetasone and antiinfectives; otic
4.2
10.8
41
105
H70
ICPC
Otitis externa
7.8
10.8
24
32
H61.2
ICD-10 Finland
Impacted cerumen
5.0
10.1
32
68
H65.0
ICD-10 Finland
Acute serous otitis media
9.4
10.1
20
22
SPAT1301
SPAT
No procedures
2.0
10.1
160
960
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
9.9
263
1895
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
8.3
9.4
20
25
H71
ICD-10 Finland
Cholesteatoma of middle ear
12.7
9.4
16
13
J01MA12
ATC
levofloxacin; systemic
2.4
9.4
89
424
H61.8
ICD-10 Finland
Other specified disorders of external ear
37.4
9.1
11
*
N02AX02
ATC
tramadol; systemic, rectal
1.9
9.0
190
1250
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
8.6
172
1109
R03AC02
ATC
salbutamol; inhalant
1.8
8.4
250
1834
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.2
8.3
43
144
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
6.8
8.0
19
29
R42
ICD-10 Finland
Dizziness and giddiness
2.1
7.9
90
468
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
7.8
143
891
SPAT1310
SPAT
Counselling related to known health issue
1.8
7.8
150
951
SPAT1262
SPAT
Handing over of treatment supplies
2.2
7.6
84
427
H65.2
ICD-10 Finland
Chronic serous otitis media
12.1
7.6
13
11
R51.80
ICD-10 Finland
Headache
2.2
7.6
82
414
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.3
7.5
68
318
A10AE04
ATC
insulin glargine; parenteral
2.8
7.4
47
179
H02AB06
ATC
prednisolone; systemic
1.7
7.4
212
1513
J01XC01
ATC
fusidic acid; systemic
11.1
7.3
13
12
H04
ICPC
Ear discharge
5.3
7.3
21
41
H62.0
ICD-10 Finland
Otitis externa in bacterial diseases classified elsewhere
+∞
7.3
7
*
H66.1
ICD-10 Finland
Chronic tubotympanic suppurative otitis media
30.5
7.2
9
*
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
30.5
7.2
9
*
H70.1
ICD-10 Finland
Chronic mastoiditis
20.4
7.2
10
5
L73.2
ICD-10 Finland
Hidradenitis suppurativa
9.0
7.1
14
16
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
4.0
7.1
27
71
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
7.0
230
1700
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
7.0
205
1465
M79.6
ICD-10 Finland
Pain in limb
1.8
7.0
159
1053
N06AX16
ATC
venlafaxine; oral
2.2
7.0
71
347
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
6.0
7.0
18
31
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.5
6.9
23
53
N05BA01
ATC
diazepam; systemic, rectal
2.3
6.9
64
300
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
6.9
96
536
Z94.0
ICD-10 Finland
Kidney transplant status
11.2
6.8
12
11
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
5.8
6.8
18
32
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.8
6.8
21
45
J01DA06
ATC
[U] cefuroxime; systemic
2.2
6.8
72
359
J01CA04
ATC
amoxicillin; systemic
1.8
6.8
385
3320
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
6.8
105
611
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
6.8
84
450
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.7
118
718
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.5
6.6
52
225
DC1AD
NOMESCO Finland
Temporalbone CT
12.5
6.6
11
9
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
10.2
6.6
12
12
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
6.5
97
557
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.9
6.4
38
140
J01AA02
ATC
doxycycline; systemic
1.7
6.4
342
2861
P01AB01
ATC
metronidazole; oral, rectal
1.7
6.3
178
1252
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
9.4
6.3
12
13
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
+∞
6.3
6
*
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
5.2
6.2
18
36
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
6.2
109
660
S10
ICPC
Boil/carbuncle
3.2
6.2
30
97
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
6.2
57
267
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.1
6.2
68
346
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
6.1
97
567
A10AA02
ATC
NA
4.5
6.1
20
46
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
6.1
108
656
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.2
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
225
1561
1.77
9.11
6.4
4.9
35.9
36.2
g/l
0.35
202
1467
306
2327
1.75
8.90
6.6
4.8
6.8
6.6
mmol/l
0.69
294
2131
181
1207
1.76
8.22
4.3
3.1
8.3
8.1
mmol/l
0.19
155
1022
166
1101
1.74
7.58
5.3
4.0
18.8
10.2
mg/mmol
0.67
115
710
19
47
4.16
7.14
1.4
1.3
—
—
—
0
0
87
481
1.97
7.08
9.1
6.0
1.1
1.0
mmol/l
0.73
82
450
143
925
1.75
7.06
2.7
2.0
2.7
3.1
mg/l
1.58
127
790
477
4282
2.22
6.82
19.9
12.5
22.1
22.7
mg/l
0.16
395
3314
202
1447
1.64
6.76
5.2
3.3
33.2
37.3
ng/l
0.27
112
911
271
2087
1.62
6.76
5.9
6.5
12.2
11.2
umol/l
0.32
255
1986
162
1107
1.67
6.47
2.5
2.1
164.2
276.4
u/l
0.96
151
1047
363
3034
1.63
6.21
4.3
3.9
12.4
10.5
mm/h
1.73
335
2817
300
2407
1.57
6.01
9.2
9.2
4.3
4.0
e9/l
1.31
275
2105
177
1257
1.62
5.99
4.0
2.7
54.7
55.2
u/l
0.07
158
1177
73
405
1.93
5.85
7.8
8.9
0.7
1.1
mmol/l
0.24
59
321
48
228
2.22
5.82
1.7
1.4
—
—
—
0
0
375
3198
1.60
5.53
4.2
3.9
14.6
14.6
pmol/l
0.01
340
2935
138
944
1.63
5.35
1.9
1.8
1.0
1.1
mg/l
0.26
101
707
195
1448
1.55
5.33
2.0
1.8
101.6
94.8
pmol/l
1.28
100
754
365
3107
1.57
5.29
8.4
7.4
81.7
77.2
u/l
0.97
343
2917
145
1019
1.58
4.99
2.8
2.6
2945.3
5111.7
umol/l
0.33
132
895
149
1064
1.56
4.76
4.0
2.8
0.8
0.4
e6/l
0.52
115
785
42
206
2.13
4.73
2.1
2.4
6408.1
3383.6
u/l
0.28
15
87
93
593
1.69
4.70
3.3
2.2
13.3
14.0
umol/l
0.42
87
549
54
294
1.93
4.58
3.7
2.3
4.7
7.3
ug/l
0.69
48
266
183
1377
1.50
4.56
4.4
3.0
—
—
—
0
0
466
4266
1.81
4.54
21.7
13.8
139.5
139.7
mmol/l
0.46
460
4153
467
4280
1.81
4.51
21.7
13.9
4.0
4.0
mmol/l
0.34
460
4157
80
499
1.71
4.37
3.2
2.3
23.4
24.1
%
0.17
70
439
212
1657
1.47
4.32
8.6
6.2
1.2
1.2
mmol/l
1.32
196
1518
89
574
1.66
4.30
3.4
2.1
30.5
29.5
s
0.86
83
559
117
812
1.57
4.18
1.6
1.5
20.1
20.7
nmol/l
0.18
96
701
142
1031
1.52
4.14
1.4
1.3
2.3
2.0
u/ml
0.09
32
305
227
1813
1.44
4.07
10.3
6.8
1.2
1.2
mmol/l
1.15
195
1540
20
75
2.73
4.03
2.8
2.0
129.2
130.9
g/l
0.13
15
57
89
588
1.62
3.90
2.2
1.9
—
—
—
0
0
248
2034
1.41
3.75
6.1
4.5
0.0
0.0
estimate
0.50
59
392
201
1605
1.41
3.47
2.7
2.2
73.6
73.9
nmol/l
0.04
183
1450
90
613
1.56
3.47
2.7
2.8
2.4
2.4
mmol/l
0.10
76
531
245
2025
1.39
3.45
4.5
3.3
0.0
0.0
estimate
0.00
57
388
90
614
1.56
3.44
2.0
1.7
1183.3
1148.3
nmol/l
0.14
66
465
64
403
1.67
3.39
2.3
1.7
—
—
—
0
0
56
345
1.70
3.22
6.4
3.8
0.8
1.9
mmol/l
1.21
44
271
60
378
1.66
3.18
3.8
2.4
37.6
157.1
u/l
0.46
54
321
158
1229
1.41
3.12
3.8
3.2
2.3
2.3
mmol/l
0.08
135
1089
246
2060
1.36
3.09
4.6
3.3
0.0
0.0
estimate
0.00
58
373
98
700
1.49
3.03
5.1
3.7
128.9
322.5
ng/l
0.80
75
493
422
3870
1.46
2.97
5.2
4.5
1.8
1.9
mu/l
0.04
382
3602
22
102
2.21
2.91
2.0
1.6
—
—
—
0
0
58
372
1.63
2.88
3.5
2.9
—
—
—
0
0
86
606
1.50
2.84
3.1
2.7
2.4
2.1
e6/l
0.14
51
315
100
728
1.46
2.81
1.3
1.3
10.4
33.1
iu/ml
5.91
23
237
62
410
1.58
2.72
2.3
1.8
—
—
—
0
0
194
1593
1.35
2.67
4.7
3.4
—
—
—
0
0
48
300
1.66
2.64
2.0
2.4
70.2
72.3
ml/min/173m2
0.10
19
121
230
1946
1.32
2.56
4.3
4.0
—
—
—
0
0
409
3767
1.39
2.49
7.3
5.2
41.4
39.2
mmol/mol
2.93
382
3545
14
57
2.50
2.47
2.1
1.3
—
—
—
0
0
125
969
1.38
2.46
1.9
1.6
—
—
—
0
0
16
70
2.33
2.43
1.3
1.6
—
—
—
0
0
95
704
1.43
2.43
1.3
1.3
1.1
10.4
u/ml
3.62
32
293
428
3978
1.41
2.42
16.6
11.0
87.8
87.1
ml/min/173m2
0.20
367
3243
224
1907
1.30
2.32
3.5
2.7
138.2
111.8
ug/l
0.73
208
1779
43
273
1.63
2.25
1.7
1.6
—
—
—
0
0
26
143
1.86
2.23
1.8
2.2
1.5
1.4
g/l
0.16
20
128
40
251
1.64
2.20
6.3
3.9
116.7
79.9
ng/l
1.24
33
228
347
3145
1.30
2.18
3.3
3.4
—
—
—
0
0
334
3013
1.30
2.17
3.6
3.1
55.5
45.1
u/l
1.14
316
2851
27
152
1.82
2.16
1.8
1.8
—
—
—
0
0
64
451
1.48
2.13
11.3
6.5
—
—
—
0
0
25
138
1.85
2.13
1.5
1.8
—
—
—
0
0
37
230
1.65
2.11
4.3
3.5
1.9
1.6
mmol/l
0.24
27
170
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
103
1.98
2.08
5.2
3.0
0.3
0.3
u/ml
0.06
11
58
16
76
2.14
2.04
1.1
1.2
5.8
2.9
u/ml
0.26
11
35
6
15
4.03
2.04
1.2
1.3
—
—
—
0
0
18
90
2.04
2.02
1.3
1.2
—
—
—
0
0
26
149
1.78
1.98
2.1
1.6
—
—
—
0
0
119
947
1.33
1.96
3.7
3.2
1451.5
1049.3
ng/l
0.57
100
787
449
4245
1.39
1.96
5.3
4.4
2.7
2.8
mmol/l
1.33
417
3961
134
1085
1.32
1.96
4.9
3.5
0.0
0.0
estimate
0.80
59
384
48
325
1.52
1.94
2.2
2.4
0.2
0.2
g/l
0.17
43
305
6
16
3.78
1.94
1.2
1.3
—
—
—
0
0
85
650
1.37
1.82
3.1
2.5
1.6
0.9
e6/l
0.76
51
355
20
109
1.87
1.79
1.2
1.5
315.2
307.4
ug/g
0.07
13
65
172
1460
1.26
1.73
3.0
3.5
53.1
31.6
u/l
0.49
159
1393
21
119
1.80
1.68
2.2
2.8
—
—
—
0
0
129
1061
1.29
1.67
1.8
1.6
1.4
1.4
mmol/l
0.18
107
910
25
150
1.70
1.66
1.6
2.1
—
—
—
0
0
97
770
1.32
1.63
1.7
1.7
478.0
432.8
pmol/l
0.94
76
671
441
4187
1.33
1.62
5.0
4.0
4.5
4.7
mmol/l
2.13
414
3934
58
425
1.41
1.61
23.5
18.7
1.2
1.2
inr
—
7
57
427
4040
1.30
1.58
5.0
4.0
6.1
5.9
mmol/l
2.10
385
3725
6
20
3.02
1.58
1.2
1.3
—
—
—
0
0
474
4558
1.40
1.53
11.9
9.6
28.8
27.6
u/l
0.66
460
4423
438
4165
1.31
1.51
4.8
4.0
1.4
1.4
mmol/l
1.55
410
3898
83
652
1.32
1.50
1.8
1.8
1.6
1.5
%
0.49
75
590
500
4863
1.57
1.45
27.4
18.3
135.6
137.4
g/l
1.85
495
4798
87
694
1.30
1.42
2.4
2.0
—
—
—
0
0
11
53
2.10
1.39
1.4
1.5
—
—
—
0
0
30
199
1.54
1.38
1.5
1.5
—
—
—
0
0
6
24
2.52
1.30
1.2
1.3
—
—
—
0
0
8
34
2.37
1.29
1.0
1.1
—
—
—
0
0
34
476
0.69
1.25
1.6
1.7
—
—
—
0
0
6
25
2.42
1.24
2.0
3.4
—
—
—
0
0
12
64
1.90
1.19
1.3
1.5
—
—
—
0
0
421
4017
1.24
1.19
4.5
3.6
1.4
1.3
mmol/l
1.27
393
3748
18
110
1.66
1.17
3.2
2.2
124.6
53.0
ug/min
0.45
12
59
8
39
2.07
1.15
1.0
1.2
—
—
—
0
0
61
481
1.30
1.11
2.1
2.9
9.3
8.2
umol/l
0.14
52
418
92
765
1.25
1.10
2.5
2.1
—
—
—
0
0
5
21
2.39
1.09
1.2
1.2
—
—
—
0
0
114
979
1.21
1.01
2.4
2.2
—
—
—
0
0
7
35
2.01
1.00
1.3
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
23
2.18
0.98
1.2
1.3
—
—
—
0
0
26
182
1.45
0.98
1.3
1.4
283.7
253.7
miu/ml
—
9
92
9
51
1.78
0.95
1.2
1.3
—
—
—
0
0
13
78
1.68
0.92
1.1
1.2
—
—
—
0
0
6
28
2.16
0.91
1.0
1.3
3.8
1.9
mmol/l
—
6
28
14
86
1.65
0.91
1.1
1.2
—
1.0
—
0
7
108
934
1.20
0.89
4.2
3.4
1.0
1.0
kg/l
0.17
16
129
8
42
1.92
0.89
1.0
1.0
—
—
—
0
0
143
1271
1.17
0.86
4.7
4.3
2.5
2.2
ug/l
0.24
129
1154
422
4066
1.19
0.86
19.6
13.3
39.3
40.7
%
2.16
288
3179
12
73
1.66
0.82
1.3
1.5
—
—
—
0
0
6
33
1.83
0.79
1.3
1.6
—
—
—
0
0
15
98
1.55
0.79
1.7
4.3
122.4
110.5
mg/l
—
9
83
0
25
0.00
0.79
0.0
3.1
—
—
—
0
0
24
174
1.40
0.78
2.3
1.4
10.7
9.2
u/l
0.21
19
145
42
333
1.28
0.77
1.2
1.3
214.9
160.4
iu/ml
—
10
142
42
334
1.28
0.76
1.7
1.8
—
—
—
0
0
9
55
1.65
0.74
1.2
1.4
—
—
—
0
0
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
7
40
1.76
0.71
1.0
1.8
—
—
—
0
0
5
26
1.93
0.71
1.2
1.2
154.4
120.2
iu/ml
—
5
26
15
102
1.48
0.68
1.1
1.2
—
—
—
0
0
7
43
1.64
0.67
1.0
1.1
—
—
—
0
0
27
206
1.33
0.67
1.6
1.4
420.0
286.5
mu/l
0.66
22
185
25
189
1.34
0.65
4.8
2.9
1.3
1.4
%
0.19
25
189
15
103
1.47
0.65
1.3
1.3
143.1
243.8
u/ml
—
10
64
7
44
1.60
0.65
1.0
1.1
—
—
—
0
0
7
44
1.60
0.65
2.7
3.3
—
—
—
0
0
14
95
1.49
0.64
1.7
4.2
—
1.2
—
0
14
21
279
0.74
0.63
1.2
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
14
98
1.44
0.57
1.7
4.3
52.0
33.8
mg/l
—
8
84
13
90
1.46
0.56
1.2
1.2
—
—
—
0
0
6
37
1.63
0.55
1.3
1.1
—
—
—
0
0
19
142
1.35
0.55
1.4
1.5
1.4
1.2
g/l
1.47
19
135
9
62
1.46
0.53
1.0
1.1
—
—
—
0
0
9
63
1.44
0.52
1.2
1.1
1.5
1.4
g/l
—
9
57
15
109
1.39
0.51
1.3
1.2
—
—
—
0
0
6
41
1.47
0.50
1.2
1.3
—
—
—
0
0
15
110
1.37
0.49
1.2
1.2
—
3.2
—
0
13
18
137
1.32
0.48
1.4
1.5
0.3
0.2
g/l
0.52
18
130
16
210
0.75
0.47
2.1
1.9
—
—
—
0
0
19
148
1.29
0.44
1.5
1.5
—
—
—
0
0
5
31
1.62
0.43
3.4
2.2
—
—
—
0
0
16
122
1.32
0.42
1.3
1.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.2
—
68.0
—
0
5
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
23.8
—
0
16
11
79
1.40
0.41
1.1
1.0
2.7
1.5
u/ml
—
5
40
11
79
1.40
0.41
1.5
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
2.9
—
46.4
—
0
18
13
170
0.76
0.38
1.4
1.4
—
—
—
0
0
13
170
0.76
0.38
1.4
1.4
—
—
—
0
0
13
169
0.76
0.37
1.4
1.4
—
—
—
0
0
13
169
0.76
0.37
1.4
1.4
—
—
—
0
0
9
70
1.29
0.37
1.2
1.6
—
—
—
0
0
19
153
1.25
0.36
1.4
1.4
—
—
—
0
0
14
108
1.30
0.35
6.9
4.1
1.6
1.4
mg/l
0.47
14
98
29
248
1.18
0.32
1.1
1.0
—
—
—
0
0
11
83
1.33
0.32
1.7
1.5
—
—
—
0
0
15
119
1.27
0.32
1.3
1.4
—
—
—
0
0
13
102
1.28
0.30
1.5
1.4
113.1
102.8
u/ml
—
6
24
7
56
1.25
0.29
1.1
1.3
—
—
—
0
0
15
184
0.81
0.29
1.5
1.5
—
—
—
0
0
11
85
1.30
0.28
2.6
1.3
—
—
—
0
0
11
85
1.30
0.28
2.6
1.3
—
—
—
0
0
47
424
1.12
0.27
2.0
1.9
—
—
—
0
0
9
72
1.25
0.25
3.8
4.0
—
2779.3
—
0
10
12
148
0.81
0.25
1.2
1.1
—
—
—
0
0
50
457
1.10
0.24
4.3
4.0
32.2
30.8
%
0.42
35
316
5
38
1.32
0.23
1.0
1.2
—
—
—
0
0
5
39
1.28
0.23
1.0
1.1
—
—
—
0
0
5
39
1.28
0.23
1.0
1.2
—
—
—
0
0
12
146
0.82
0.22
1.2
1.1
—
—
—
0
0
5
41
1.22
0.22
29.4
18.4
1707.6
1453.4
nmol/l
—
5
41
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
8
101
0.79
0.21
1.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
41
377
1.09
0.18
3.0
2.4
10.8
13.7
nmol/l
1.17
30
347
8
68
1.18
0.16
1.1
1.1
—
—
—
0
0
8
72
1.11
0.16
5.8
5.8
422.8
372.2
umol/l
—
8
65
12
102
1.18
0.15
1.3
1.5
773.4
402.5
mg/l
0.67
12
95
74
704
1.06
0.15
1.4
1.4
—
—
—
0
0
8
96
0.83
0.14
1.3
1.4
—
—
—
0
0
105
1012
1.05
0.14
3.6
4.0
23.6
20.9
%
0.76
47
427
29
311
0.93
0.11
1.4
1.5
—
—
—
0
0
5
45
1.11
0.10
2.0
1.1
—
—
—
0
0
5
46
1.09
0.09
1.2
1.8
—
—
—
0
0
10
114
0.87
0.09
1.3
1.5
—
—
—
0
0
5
47
1.06
0.09
1.2
1.1
—
—
—
0
0
6
71
0.84
0.07
1.3
1.1
—
—
—
0
0
20
214
0.93
0.07
1.3
1.4
—
—
—
0
0
9
102
0.88
0.06
1.4
1.5
—
—
—
0
0
34
354
0.96
0.05
2.7
4.3
4.6
42.7
ug/l
1.01
25
291
10
91
1.10
0.04
2.4
1.9
—
—
—
0
0
10
91
1.10
0.04
1.3
1.5
4.0
3.7
mmol/l
—
10
82
10
92
1.09
0.03
2.7
1.8
—
—
—
0
0
13
136
0.95
0.00
1.5
1.5
—
—
—
0
0
15
145
1.04
0.00
1.9
2.0
—
—
—
0
0
13
126
1.03
0.00
1.2
2.3
—
—
—
0
0
21
213
0.99
0.00
1.6
2.4
23.1
32.3
u/ml
0.45
21
203
10
99
1.01
0.00
1.4
1.6
—
—
—
0
0
73
732
1.00
0.00
2.7
2.7
0.8
0.7
ug/l
0.25
48
440
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.2
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
17
170
1.00
0.00
1.3
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
7
78
0.90
0.00
1.3
1.2
—
—
—
0
0
7
74
0.95
0.00
1.0
1.1
—
—
—
0
0
13
130
1.00
0.00
1.8
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXT_ABSC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_ABSC | 1.518 [1.23, 1.88] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.427 |
During the follow-up period (1.1.1998 — 31.12.2019), 227 out of 1895 females with H8_EXT_ABSC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_ABSC | 1.552 [1.3, 1.85] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 326 out of 2212 males with H8_EXT_ABSC died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXT_ABSC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.136% | 0.284% |
| 5 | 0.798% | 1.831% |
| 10 | 2.06% | 4.494% |
| 15 | 4.252% | 8.106% |
| 20 | 7.656% | 13.681% |
Relationships between endpoints
↥Index endpoint: H8_EXT_ABSC – Abscess of external ear
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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