Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

O15_MATERN_INFECT_ELSEWHERE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O98
  • Hospital discharge: ICD-9 647
  • Cause of death: ICD-10 O98
  • Cause of death: ICD-9 647

2 out of 7 registries used, show all original rules.

807

4. Check minimum number of events

None

807

5. Include endpoints

None

807

6. Filter based on genotype QC (FinnGen only)

807

Control definitions (FinnGen only)

Control exclude
O15_OBSTET_NAS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O94-O99
Name in latin
Morbi infectiosi et parasitici materni alibi classificabiles sed complicantes graviditatem, partum et puerperium

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6905 6905 -
Only index persons 6801 6801 -
Unadjusted period prevalence (%)
Whole population 0.20 0.20 -
Only index persons 0.25 0.25 -
Median age at first event (years)
Whole population - 29.22 -
Only index persons - 29.24 -

-FinnGen-

Key figures

All Female Male
Number of individuals 807 807 -
Unadjusted period prevalence (%) 0.28 0.28 -
Median age at first event (years) 29.43 29.43 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
743
Matched controls
7430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O98.8
ICD-10 Finland
Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium
+∞
142.4
132
*
O98.5
ICD-10 Finland
Other viral diseases complicating pregnancy, childbirth and the puerperium
+∞
134.6
125
*
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
+∞
134.6
125
*
O98.3
ICD-10 Finland
Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium
+∞
127.9
119
*
O99.80
ICD-10 Finland
The fear of childbirth
+∞
99.2
93
*
6478X
ICD-9 Finland
Infective and parasitic conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other specified infective and parasitic diseases
+∞
84.0
79
*
B18.2
ICD-10 Finland
Chronic viral hepatitis C
33.7
80.0
105
36
6476A
ICD-9 Finland
Infective and parasitic conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other viral diseases
+∞
64.5
61
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
4.8
62.0
246
691
O98.9
ICD-10 Finland
Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium
+∞
61.3
58
*
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
321.9
59.2
59
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
3.2
44.7
324
1444
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.9
40.8
146
351
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
144.4
39.1
41
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
3.6
38.8
209
728
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
2.9
38.3
322
1543
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
53.1
38.0
45
9
Z72.2
ICD-10 Finland
Drug use
63.4
36.5
42
7
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
177.9
33.0
34
*
P19
ICPC
Drug abuse
19.9
30.0
45
24
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.4
29.5
456
2932
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
10.9
29.5
57
56
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
59.2
29.4
34
6
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.8
27.9
221
977
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
2.4
27.4
403
2487
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
39.5
27.3
34
9
XMA22
NOMESCO Finland
General examination of pregnant woman
3.5
27.0
140
462
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.8
26.2
202
874
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
+∞
26.2
25
*
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
8.7
26.1
57
70
Z86.4
ICD-10 Finland
Personal history of psychoactive substance abuse
35.9
24.4
31
9
SPAT1272
SPAT
Drug screening
32.3
23.9
31
10
J05AB01
ATC
aciclovir; systemic
2.5
23.7
229
1119
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.8
23.0
166
684
WX234
NOMESCO Finland
Paracervical blockade
4.7
22.7
80
185
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
6.3
22.4
61
104
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
2.6
22.3
186
834
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
40.0
21.8
27
7
F11.20
ICD-10 Finland
Addiction-induced dependence caused by opiates currently independent
51.6
21.2
25
5
WX740
NOMESCO Finland
Nitrogen oxide therapy
22.3
21.0
30
14
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
2.4
20.0
212
1073
Z22.5
ICD-10 Finland
Carrier of viral hepatitis
75.6
19.8
22
*
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.2
18.9
241
1322
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
39.5
18.6
23
6
SPAT1275
SPAT
Drug rehabilitation and replacement therapy of opioid-dependent person
18.1
18.4
28
16
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
20.0
18.3
27
14
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.5
18.3
162
741
O98.0
ICD-10 Finland
Tuberculosis complicating pregnancy, childbirth and the puerperium
+∞
17.8
17
*
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
32.3
17.1
22
7
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
92.2
16.6
18
*
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.6
16.2
127
541
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
19.0
16.1
24
13
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.0
15.8
251
1496
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
+∞
15.7
15
*
W78
ICPC
Pregnancy
2.0
15.6
247
1466
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
86.9
15.6
17
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
86.9
15.6
17
*
P01AB01
ATC
metronidazole; oral, rectal
1.9
15.5
351
2379
W84
ICPC
Pregnancy high risk
3.4
14.9
75
238
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
18.8
14.8
22
12
F13.20
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent
21.6
14.7
21
10
6479X
ICD-9 Finland
Infective and parasitic conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Unspecified infection or infestation
+∞
14.6
14
*
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
36.8
14.5
18
5
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
5.3
14.5
44
87
SPAT1379
SPAT
Health check-up of pregnant person
2.1
14.2
189
1035
R3110
NOMESCO Finland
Psychosocial training
12.3
14.2
25
21
N06AB04
ATC
citalopram; systemic
2.1
13.5
186
1035
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.4
13.3
65
202
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
40.9
13.2
16
*
SPAT1265
SPAT
Breathalyser
12.4
13.2
23
19
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
11.2
13.1
24
22
A60.9
ICD-10 Finland
Anogenital herpesviral infection, unspecified
19.5
13.0
19
10
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.2
12.8
144
732
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.7
12.4
55
159
SPAT1197
SPAT
Extensive health check-up of expecting family
1.9
12.2
214
1295
LCH11
NOMESCO Finland
Pharmacologic abortion
2.7
12.2
87
350
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.1
12.1
144
749
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
12.1
304
2082
8811
FHL
Cesarean section
2.8
11.8
79
304
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
3.2
11.7
63
211
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
11.6
401
3010
TQX20
NOMESCO Finland
Implantation of subcutaneous medicament implant
10.3
11.6
22
22
6472X
ICD-9 Finland
Infective and parasitic conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Other venereal diseases
+∞
11.5
11
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.4
11.2
55
172
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
11.4
11.1
20
18
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
11.1
65
232
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
11.0
576
4864
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
44.0
10.9
13
*
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
18.1
10.8
16
9
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
16.3
10.4
16
10
Z37.0
ICD-10 Finland
Single live birth
1.9
10.4
160
920
B17.1
ICD-10 Finland
Acute hepatitis C
33.0
10.4
13
*
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.9
10.1
161
933
N05BA04
ATC
oxazepam; oral
1.8
10.1
194
1203
SPAT1254
SPAT
Administration of medicine
2.4
10.0
87
387
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.9
9.7
153
882
N05AH04
ATC
quetiapine; oral
1.9
9.7
153
885
MAX99
NOMESCO Finland
Assistance to normal delivery
1.9
9.6
156
909
SGA01
NOMESCO Finland
Tooth opening as first aid
1.9
9.6
154
894
N07BB01
ATC
disulfiram; oral
4.1
9.5
36
91
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
3.0
9.5
55
194
R74
ICPC
Upper respiratory infection acute
1.7
9.5
309
2234
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
101.3
9.4
10
*
D72
ICPC
Viral hepatitis
101.3
9.4
10
*
F19.30
ICD-10 Finland
Withdrawal symptoms caused by several drugs in combination and by other psychoactive substances uncomplicated
30.4
9.4
12
*
339
Kela drug reimbursment
Product containing buprenorfine and naloxone
+∞
9.4
9
*
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
9.4
9
*
Z30.2
ICD-10 Finland
Sterilization
2.0
9.3
131
726
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
9.2
237
1603
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
3.0
9.1
52
181
J05AB11
ATC
valaciclovir; oral
2.1
9.1
111
579
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.6
9.1
427
3386
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
15.8
9.1
14
9
SPAT1227
SPAT
Substance abuse rehabilitation
15.8
9.1
14
9
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
4.1
9.0
34
86
N03AX16
ATC
pregabalin; oral
1.9
9.0
151
888
SPAT1380
SPAT
Postpartum check-up
1.9
9.0
146
851
Z29
ICPC
Social problem NOS
4.7
9.0
29
63
WX290
NOMESCO Finland
Other blockade of nerve
1.6
9.0
409
3217
A02BC01
ATC
omeprazole; systemic
1.8
9.0
162
978
O80.8
ICD-10 Finland
Other single spontaneous delivery
2.4
8.8
75
332
N03AE01
ATC
clonazepam; systemic
3.3
8.8
44
141
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
8.8
129
723
LCH00
NOMESCO Finland
Vacuum aspiration of products of conception from uterus
2.8
8.8
56
212
F19.2
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, dependence syndrome
50.6
8.7
10
*
N05BA01
ATC
diazepam; systemic, rectal
2.2
8.6
86
411
O35.4
ICD-10 Finland
Maternal care for (suspected) damage to fetus from alcohol
27.9
8.5
11
*
RS310
NOMESCO Finland
NA
27.9
8.5
11
*
RS120
NOMESCO Finland
NA
27.9
8.5
11
*
AA1AD
NOMESCO Finland
CT of head and brain
2.0
8.3
103
542
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.3
8.3
41
131
K02.1
ICD-10 Finland
Caries of dentine
1.6
8.3
470
3871
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
11.9
8.1
14
12
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.6
8.1
417
3346
K04.08
ICD-10 Finland
Other specified pulpit
2.3
8.0
77
361
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.7
8.0
54
210
M01AE01
ATC
ibuprofen; systemic, rectal
2.2
8.0
694
6428
N06AB10
ATC
escitalopram; oral
1.7
8.0
195
1292
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
7.9
104
561
R42
ICD-10 Finland
Dizziness and giddiness
1.9
7.8
121
693
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
7.7
330
2519
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
7.7
202
1361
N06AX16
ATC
venlafaxine; oral
1.8
7.6
135
807
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
5.5
7.6
21
39
A05AA02
ATC
ursodeoxycholic acid; oral
4.2
7.6
27
66
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
7.4
71
333
IFC01
NOMESCO Finland
Withdrawal and replacement therapy for opioid addiction
80.9
7.4
8
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
7.4
136
824
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
+∞
7.3
7
*
O98.1
ICD-10 Finland
Syphilis complicating pregnancy, childbirth and the puerperium
+∞
7.3
7
*
N07BC51
ATC
buprenorphine, combinations; sublingual
+∞
7.3
7
*
XLA10
NOMESCO Finland
NA
2.4
7.3
62
274
S06.0
ICD-10 Finland
Concussion
2.2
7.3
72
343
RS312
NOMESCO Finland
NA
30.3
7.2
9
*
F19.21
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances currently independent but staying in a controlling environment
30.3
7.2
9
*
D11
ICPC
Diarrhoea
1.9
7.1
109
618
EBA30
NOMESCO Finland
Excision of root of tooth
3.7
7.1
29
80
J01DA01
ATC
[U] cefalexin; systemic
1.5
7.1
467
3907
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.3
7.1
33
102
D10
ICPC
Vomiting
2.1
7.1
78
392
W85
ICPC
Gestational diabetes
2.3
7.0
63
285
R53
ICD-10 Finland
Malaise and fatigue
1.7
7.0
147
925
K04.0
ICD-10 Finland
Pulpitis
1.9
7.0
101
563
N02BE01
ATC
paracetamol; systemic, rectal
1.6
6.9
602
5364
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
2.3
6.9
60
269
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.4
6.9
31
93
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
13.9
6.9
11
8
P18
ICPC
Medication abuse
8.4
6.8
14
17
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
2.0
6.8
86
453
MAA00
NOMESCO Finland
Amniocentesis
2.9
6.8
39
138
6412B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Premature separation of placenta[ABLATIO PLACENTAE ANTETEMPUS,SYNN PÄÄTT HOITOJAKSO]
40.4
6.8
8
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.8
6.8
21
45
-1
NOMESCO Finland
NA
1.5
6.8
280
2104
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.2
6.7
68
327
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
2.1
6.7
73
366
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
12.4
6.6
11
9
Z36.9
ICD-10 Finland
Antenatal screening, unspecified
3.4
6.5
30
92
R50.9
ICD-10 Finland
Fever, unspecified
1.9
6.5
92
509
WX306
NOMESCO Finland
Lumbar epidural anesthesy
1.9
6.5
90
495
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
2.5
6.5
49
206
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
6.4
79
413
SPAT1196
SPAT
Monitoring of normal pregnancy
1.8
6.4
113
675
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
6.3
233
1698
W01
ICPC
Question of pregnancy
4.6
6.3
20
44
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
3.1
6.3
32
106
N05BA12
ATC
alprazolam; oral
2.0
6.3
76
395
G02CB01
ATC
bromocriptine; systemic
3.2
6.3
31
101
F11.21
ICD-10 Finland
Addiction-indiced dependence caused by opiates currently independent but staying in controlling environment
26.9
6.2
8
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
6.2
117
714
R2110
NOMESCO Finland
Giving the first information
2.1
6.2
70
356
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
2.2
6.2
60
283
A02BC02
ATC
pantoprazole; systemic
1.5
6.1
401
3300
N01
ICPC
Headache
1.8
6.1
106
627
K04.1
ICD-10 Finland
Necrosis of pulp
2.0
6.1
81
438
N77.1*A60.0
ICD-10 Finland
Vaginitis, vulvitis and vulvovaginitis in herpesviral [herpes simplex] infection
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
75
203
3.97
24.76
9.5
1.8
—
—
—
0
0
101
335
3.30
24.60
17.5
2.1
—
—
—
0
0
27
27
10.31
23.93
2.6
3.0
33.3
52.1
%
—
10
11
326
2008
2.05
20.69
2.0
1.7
—
—
—
0
0
330
2067
2.01
19.77
3.5
3.9
37.4
37.2
g/l
0.34
307
1937
63
180
3.71
19.22
2.6
2.3
4.6
4.8
umol/l
0.09
51
131
412
2823
1.94
18.67
5.5
5.1
9.4
9.5
umol/l
0.10
387
2663
114
471
2.65
18.55
8.5
1.5
—
—
—
0
0
107
435
2.68
17.96
9.5
1.5
—
—
—
0
0
113
475
2.60
17.73
9.2
1.5
—
—
—
0
0
113
478
2.59
17.50
9.6
1.5
—
—
—
0
0
96
375
2.77
17.39
10.2
1.5
—
—
—
0
0
112
475
2.58
17.24
9.5
1.5
—
—
—
0
0
313
2016
1.90
16.56
3.3
2.9
51.6
54.7
e6/l
0.06
195
1265
234
1368
2.00
16.48
3.1
3.0
97.9
99.9
%
0.79
225
1320
253
1526
1.96
16.25
2.7
2.6
204.8
166.9
e6/l
0.07
181
1136
20
6
34.12
15.79
6.0
1.8
—
—
—
0
0
572
4499
1.93
15.78
6.8
6.2
71.5
72.3
u/l
0.19
541
4244
402
2846
1.82
15.41
8.8
7.2
0.0
0.0
e9/l
0.52
328
2352
358
2453
1.83
15.23
2.3
2.0
—
—
—
0
0
298
1932
1.86
15.14
6.0
5.4
—
—
—
0
0
49
141
3.64
14.79
4.9
3.2
0.1
0.4
g/l
1.19
33
48
228
1372
1.92
14.49
2.8
2.5
0.2
0.3
e6/l
1.39
164
996
122
582
2.29
14.40
3.4
2.9
—
—
—
0
0
200
1156
1.97
14.29
2.0
1.5
—
—
—
0
0
108
494
2.37
14.03
6.2
4.7
1.0
1.0
mmol/l
0.41
103
463
111
514
2.34
14.03
2.6
2.2
31.6
41.6
u/l
0.98
96
425
228
1389
1.89
13.87
2.7
2.4
—
—
—
0
0
98
452
2.33
12.46
1.5
1.3
—
—
—
0
0
256
1663
1.79
12.44
2.6
2.0
—
—
—
0
0
418
3139
1.69
11.88
4.3
3.7
6.0
6.2
mmol/l
1.16
388
2815
177
1046
1.89
11.58
2.2
2.2
10.0
9.4
e6/l
0.13
161
918
21
37
5.80
11.52
4.9
1.2
—
—
—
0
0
539
4371
1.70
11.11
4.6
3.5
79.5
832.5
e6/l
—
8
42
431
3307
1.65
10.92
3.5
2.9
0.0
0.0
estimate
0.50
112
622
251
1678
1.72
10.76
1.9
1.6
—
—
—
0
0
430
3306
1.64
10.74
4.8
4.1
0.0
0.0
estimate
0.38
112
651
42
140
3.11
10.10
1.8
1.2
—
—
—
0
0
430
3343
1.61
9.98
3.6
3.0
0.0
0.0
estimate
1.06
114
630
164
995
1.81
9.73
5.2
3.5
—
—
—
0
0
30
84
3.67
9.46
2.3
2.1
2.0
2.1
mmol/l
0.13
17
52
553
4606
1.64
9.38
4.4
3.5
—
—
—
0
0
34
106
3.30
9.13
1.1
1.0
—
—
—
0
0
379
2901
1.58
9.09
6.8
5.3
0.7
0.7
%
0.40
353
2712
427
3363
1.57
9.02
6.7
5.6
0.2
0.2
e9/l
0.11
387
3043
13
18
7.32
8.86
1.2
1.1
—
—
—
0
0
748
6844
2.27
8.74
11.8
9.3
19.2
17.9
mg/l
0.50
599
5148
227
1560
1.63
8.43
7.2
6.1
—
—
—
0
0
389
3033
1.55
8.37
6.6
5.2
2.6
2.7
%
0.10
361
2831
154
958
1.75
8.30
2.5
2.3
511.2
526.0
mosm/kgh2o
0.37
136
819
125
732
1.84
8.24
2.1
1.4
—
—
—
0
0
80
403
2.09
8.16
1.6
2.3
0.2
0.2
g/l
0.00
71
385
133
797
1.80
8.13
2.3
2.1
8185.7
4775.6
u/l
0.58
49
324
390
3058
1.53
8.08
6.9
5.4
7.5
7.7
%
0.78
368
2887
197
1322
1.65
7.99
6.4
3.1
7.4
7.8
mmol/l
0.49
166
1167
407
3226
1.53
7.98
6.7
5.3
0.5
0.5
e9/l
0.42
356
2877
408
3237
1.53
7.96
6.7
5.3
0.0
0.0
e9/l
0.15
356
2874
32
105
3.13
7.93
1.1
1.0
—
—
—
0
0
26
76
3.50
7.72
1.7
2.2
—
—
—
0
0
402
3196
1.51
7.66
6.7
5.2
31.1
30.0
%
1.35
378
3015
114
666
1.83
7.55
1.8
1.5
—
—
—
0
0
765
7130
2.40
7.43
10.1
7.8
25.5
23.5
u/l
3.30
751
6951
30
100
3.08
7.26
2.3
2.6
7.4
7.4
ph
1.14
30
83
396
3168
1.49
7.14
6.6
5.0
55.2
56.3
%
1.32
371
2990
262
1929
1.53
7.02
1.8
1.7
105.1
98.9
pmol/l
0.84
123
1092
675
6065
1.69
7.02
14.3
11.0
13.4
13.4
%
0.36
663
5947
447
3672
1.49
7.02
9.1
8.1
3.8
3.9
e9/l
0.50
392
3256
279
2083
1.52
7.00
5.0
4.6
1.2
1.2
mmol/l
0.24
265
1915
238
1726
1.54
6.80
3.8
3.2
0.0
0.0
estimate
0.28
116
644
414
3369
1.47
6.69
6.6
5.3
2.1
2.0
e9/l
0.30
369
3064
198
1392
1.56
6.47
3.3
3.3
7.4
7.4
ph
0.08
52
278
212
1516
1.54
6.41
1.9
1.7
0.7
0.7
mg/l
0.06
158
1127
24
78
3.14
6.08
2.1
1.7
18.1
16.9
%
—
9
34
44
197
2.30
6.03
1.2
1.2
—
—
—
0
0
57
284
2.08
6.02
1.2
1.2
—
—
—
0
0
164
1121
1.58
6.01
1.4
1.4
491.9
544.1
titre
0.11
37
234
704
6464
1.70
5.92
10.7
8.6
3.9
3.9
mmol/l
0.36
687
6263
217
1585
1.50
5.88
3.8
4.6
1.1
1.0
inr
0.22
89
564
702
6449
1.68
5.79
10.6
8.5
139.4
139.6
mmol/l
1.62
686
6266
113
711
1.69
5.76
3.2
3.3
0.8
0.8
mmol/l
0.75
100
675
305
2391
1.44
5.73
5.4
5.1
1.2
1.2
mmol/l
0.02
254
1997
115
728
1.68
5.73
2.6
2.3
4.2
4.7
e6/l
0.16
43
372
64
339
1.96
5.72
1.8
2.2
1.6
1.7
%
0.22
56
305
456
3852
1.42
5.62
2.7
2.6
—
—
—
0
0
19
56
3.45
5.61
2.1
1.4
1.7
1.6
mmol/l
0.38
19
56
750
7039
1.93
5.50
12.0
9.5
63.4
65.4
umol/l
5.23
750
7034
116
744
1.65
5.50
2.9
2.7
62.5
354.0
ng/l
1.27
40
331
110
701
1.66
5.34
1.8
1.8
—
—
—
0
0
199
1453
1.49
5.34
2.1
2.0
2.6
2.6
mg/l
0.10
171
1261
196
1430
1.49
5.27
1.3
1.3
25.3
26.1
iu/ml
0.05
65
475
48
236
2.10
5.27
1.9
1.7
—
—
—
0
0
460
3934
1.39
5.03
3.2
2.7
58.4
60.2
ug/l
0.21
431
3744
122
810
1.60
5.02
2.5
2.2
2.4
2.4
mmol/l
0.87
93
711
544
4797
1.41
4.91
3.9
3.5
10.2
8.9
mm/h
1.91
513
4538
187
1376
1.47
4.78
2.3
2.0
124.2
122.8
u/l
0.03
175
1312
17
52
3.32
4.77
2.2
1.5
89.9
91.6
%
0.88
17
52
186
1370
1.46
4.72
1.3
1.3
6.8
10.2
u/ml
0.48
78
613
7
5
14.10
4.58
2.0
3.2
—
—
—
0
0
254
1997
1.40
4.47
3.0
2.5
—
—
—
0
0
198
1492
1.43
4.43
1.5
1.6
1.3
1.3
mmol/l
0.05
171
1335
98
637
1.61
4.40
2.4
2.2
4.4
4.7
umol/l
0.28
80
528
227
1756
1.41
4.38
2.4
2.3
54.9
56.3
u/l
0.27
206
1647
13
35
3.76
4.38
2.8
2.6
10.4
13.8
%
—
7
18
190
1425
1.44
4.36
3.8
3.1
—
—
—
0
0
607
5511
1.41
4.22
4.2
3.8
36.5
37.2
mmol/mol
1.12
572
5278
100
661
1.59
4.20
1.6
1.3
—
—
—
0
0
145
1041
1.48
4.16
1.4
1.4
19.4
20.1
nmol/l
0.32
128
946
291
2367
1.36
4.09
2.1
1.7
—
—
—
0
0
59
342
1.78
4.05
1.4
1.8
1.4
1.4
g/l
0.07
53
320
669
6202
1.46
3.97
3.8
3.3
5.5
5.5
mmol/l
0.01
625
5900
228
1791
1.38
3.97
3.1
3.1
2.4
2.3
mmol/l
1.57
197
1644
185
1414
1.40
3.77
5.7
3.1
1.0
1.0
kg/l
0.53
17
208
207
1616
1.38
3.71
1.4
1.4
2.1
2.1
g/l
0.01
125
1076
373
3185
1.32
3.66
4.5
3.7
—
—
—
0
0
32
156
2.09
3.66
2.0
2.9
1.7
1.3
%
0.86
32
156
69
431
1.66
3.65
6.2
6.8
104.4
105.0
mmol/l
0.31
69
426
142
1043
1.44
3.61
2.1
2.0
—
—
—
0
0
97
660
1.53
3.60
2.1
2.0
375.7
378.0
nmol/l
0.05
92
619
15
51
2.98
3.59
1.7
1.8
57.3
63.2
%
0.38
15
51
47
265
1.82
3.56
6.7
8.8
—
—
—
0
0
40
214
1.91
3.55
2.1
2.5
66.8
74.0
e9/l
0.78
29
158
114
806
1.48
3.53
1.1
1.1
—
—
—
0
0
27
125
2.20
3.51
1.2
1.3
—
—
—
0
0
53
313
1.74
3.45
1.9
2.9
—
—
—
0
0
16
59
2.75
3.34
1.3
1.7
—
—
—
0
0
698
6577
1.45
3.28
5.4
4.8
1.6
1.9
mu/l
0.72
664
6323
96
674
1.48
3.08
1.9
1.5
1276.9
1149.7
nmol/l
0.73
78
535
50
301
1.70
3.07
1.8
3.1
2.1
1.9
mmol/l
0.16
39
241
18
74
2.47
3.06
2.4
2.6
51.0
31.8
umol/l
0.57
12
66
627
5825
1.34
3.03
4.8
4.2
14.3
14.2
pmol/l
0.50
590
5531
26
127
2.08
3.00
1.0
1.1
—
—
—
0
0
41
237
1.77
2.90
1.7
2.0
20.5
20.5
s
0.03
31
193
51
314
1.67
2.89
6.4
6.8
1.2
1.2
mmol/l
0.05
51
299
13
47
2.79
2.82
1.5
1.1
—
—
—
0
0
201
1626
1.31
2.78
2.9
2.4
25.0
19.8
ng/l
0.15
79
612
85
596
1.48
2.76
1.8
2.2
22.8
24.6
%
0.58
72
516
68
456
1.54
2.73
2.1
2.5
11.1
10.4
g/l
0.97
61
423
24
119
2.05
2.68
1.1
1.3
92.4
109.5
u/ml
—
7
25
9
24
3.78
2.67
2.1
2.3
10.7
11.2
%
—
9
24
137
1053
1.36
2.67
1.5
1.5
432.6
21458758.7
pmol/l
1.05
115
960
82
577
1.47
2.63
1.5
1.5
276.0
303.5
mu/l
0.52
70
519
9
25
3.63
2.58
1.1
1.2
—
—
—
0
0
67
454
1.52
2.58
1.6
1.4
—
—
—
0
0
67
455
1.52
2.55
1.6
1.4
—
—
—
0
0
27
143
1.92
2.53
1.2
1.6
—
—
—
0
0
760
7348
1.59
2.49
10.8
8.7
—
—
—
0
0
22
109
2.05
2.48
3.7
3.8
3.4
4.2
e9/l
1.67
22
109
22
111
2.01
2.37
4.3
4.1
51.9
56.8
%
1.85
22
111
27
147
1.87
2.35
1.3
1.3
227.7
248.5
u/ml
0.23
22
98
210
1749
1.27
2.29
4.1
3.8
—
—
—
0
0
13
53
2.48
2.28
1.4
1.2
—
—
—
0
0
13
53
2.48
2.28
1.0
1.1
13.1
6.6
iu/ml
—
5
19
28
156
1.82
2.28
1.3
1.4
22.7
6.6
e6/l
0.41
19
128
28
156
1.82
2.28
1.5
1.5
14.6
123.6
e6/l
1.90
20
134
235
1986
1.26
2.26
2.0
1.9
—
—
—
0
0
102
775
1.36
2.15
1.8
2.1
13.8
15.0
umol/l
0.91
91
720
56
382
1.50
2.12
3.5
10.3
1.0
1.1
inr
1.65
16
72
67
476
1.44
2.08
1.7
1.4
—
—
—
0
0
9
31
2.92
2.07
2.6
1.7
—
—
—
0
0
15
69
2.20
2.05
1.2
1.8
—
—
—
0
0
15
69
2.20
2.05
1.8
2.2
—
—
—
0
0
103
793
1.34
2.00
1.3
1.2
175.4
161.1
iu/ml
0.14
50
327
24
134
1.82
1.97
2.0
2.7
—
—
—
0
0
705
6768
1.33
1.96
12.9
9.9
39.5
39.7
%
0.44
584
5757
794
7802
2.10
1.96
18.2
13.8
90.2
90.0
fl
0.38
789
7733
794
7803
2.09
1.94
18.2
13.8
30.1
30.0
pg
0.89
789
7732
6
16
3.77
1.93
5.0
3.0
8.3
5.1
%
—
6
16
6
16
3.77
1.93
4.7
2.9
—
—
—
0
0
226
1934
1.23
1.91
1.3
1.3
0.6
1.5
u/ml
2.10
76
556
27
158
1.73
1.91
10.1
10.7
—
—
—
0
0
794
7805
2.07
1.90
18.2
13.9
4.4
4.5
e12/l
4.13
779
7666
794
7806
2.07
1.88
18.3
13.9
6.9
6.7
e9/l
0.64
782
7651
149
1218
1.27
1.88
2.7
2.4
—
—
—
0
0
8
28
2.88
1.86
4.5
3.3
0.2
0.2
e9/l
—
8
28
793
7795
2.00
1.84
18.4
13.9
264.9
271.0
e9/l
2.10
781
7655
86
655
1.35
1.81
1.2
1.2
—
—
—
0
0
794
7812
2.02
1.77
18.4
13.9
132.1
133.6
g/l
3.30
789
7743
17
88
1.95
1.76
1.2
1.3
—
—
—
0
0
23
132
1.76
1.75
1.1
1.3
—
—
—
0
0
9
36
2.52
1.74
3.9
2.2
—
3.8
—
0
6
11
48
2.31
1.71
3.4
3.3
—
—
—
0
0
78
591
1.35
1.71
2.6
3.4
4.5
4.6
pmol/l
0.08
71
526
51
359
1.45
1.70
9.0
7.6
1.1
1.0
mmol/l
0.12
40
256
31
197
1.60
1.65
2.9
2.0
—
—
—
0
0
19
106
1.81
1.60
1.2
1.1
1.1
4372.2
iu/ml
—
7
29
11
51
2.17
1.51
1.5
2.1
—
—
—
0
0
65
490
1.36
1.49
1.3
1.2
—
—
—
0
0
683
6583
1.24
1.45
3.9
3.4
2.9
2.9
mmol/l
0.35
645
6298
87
688
1.30
1.45
1.8
2.1
2.5
2.5
g/l
0.06
80
643
5
16
3.14
1.44
1.0
1.1
5.4
5.9
mg/g
—
5
16
13
66
1.99
1.44
1.2
1.7
—
—
—
0
0
6
22
2.74
1.43
2.0
1.9
13.6
30.5
ug/l
—
6
22
6
22
2.74
1.43
1.8
3.7
—
—
—
0
0
322
2923
1.17
1.37
2.0
1.9
—
—
—
0
0
33
224
1.49
1.35
1.4
1.1
—
—
—
0
0
12
61
1.98
1.33
1.3
1.1
—
—
—
0
0
15
83
1.82
1.32
1.5
2.7
23.1
24.6
mmol/l
1.46
15
75
8
34
2.37
1.29
1.9
3.3
—
—
—
0
0
58
441
1.34
1.29
1.2
1.2
—
—
—
0
0
5
18
2.79
1.28
1.0
1.1
—
—
—
0
0
677
6539
1.22
1.28
3.7
3.3
4.8
4.9
mmol/l
0.46
648
6295
10
48
2.10
1.28
5.7
2.9
—
—
—
0
0
17
99
1.73
1.28
2.5
2.5
—
—
—
0
0
168
1452
1.20
1.27
1.8
1.9
—
—
—
0
0
8
35
2.30
1.27
1.1
1.8
29.9
31.8
pg
—
8
35
6
25
2.41
1.24
1.0
1.9
121.3
141.2
nmol/l
—
6
25
9
45
2.01
1.23
1.3
1.2
—
—
—
0
0
19
116
1.65
1.22
2.2
3.2
0.9
1.3
mg/l
4.18
19
108
8
37
2.17
1.21
1.0
1.2
1341.7
1650.7
miu/ml
—
8
37
674
6516
1.21
1.21
3.6
3.2
1.5
1.6
mmol/l
2.52
642
6254
57
438
1.32
1.19
1.1
1.1
—
—
—
0
0
20
126
1.60
1.15
1.4
1.2
2.1
5.8
u/ml
—
8
44
61
480
1.29
1.09
1.3
1.3
183.6
230.2
miu/ml
0.60
26
251
123
1051
1.20
1.07
2.0
2.2
85.9
86.1
ug/g
0.00
98
809
103
866
1.22
1.06
1.2
1.2
—
—
—
0
0
17
106
1.62
1.03
1.5
2.0
—
—
—
0
0
7
34
2.07
1.03
1.1
2.6
—
—
—
0
0
9
47
1.93
1.02
1.1
1.3
—
—
—
0
0
9
47
1.93
1.02
1.1
1.2
—
—
—
0
0
29
205
1.43
1.02
1.1
1.2
—
—
—
0
0
70
569
1.25
0.99
2.2
2.2
18.9
20.5
au/ml
—
6
45
18
116
1.56
0.97
2.1
3.2
18.5
23.3
mg/l
—
9
77
46
355
1.31
0.97
1.0
1.1
—
—
—
0
0
46
357
1.31
0.94
3.9
4.0
2.8
109.3
ug/l
0.54
35
258
101
860
1.20
0.93
1.3
1.3
25.8
26.3
iu/l
0.05
79
734
6
28
2.15
0.91
1.5
1.3
—
—
—
0
0
28
203
1.39
0.88
9.4
6.2
—
—
—
0
0
12
72
1.68
0.85
1.4
1.2
0.1
0.5
u/ml
—
5
23
150
1331
1.16
0.85
1.6
2.0
2389.1
3190.5
umol/l
0.14
139
1209
8
47
1.71
0.81
1.4
1.4
—
—
—
0
0
19
132
1.45
0.76
5.5
5.0
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
196.0
637.4
u/l
—
6
28
5
26
1.93
0.70
1.2
1.3
—
—
—
0
0
17
239
0.71
0.69
1.0
1.1
0.9
4.2
u/ml
—
8
129
117
1037
1.15
0.69
2.6
3.3
25.6
576.0
mg/l
2.49
79
645
80
688
1.18
0.69
1.3
1.3
—
—
—
0
0
121
1076
1.15
0.68
3.2
4.0
4.4
10.7
mg/mmol
1.57
83
670
104
1176
0.87
0.67
1.3
1.3
—
—
—
0
0
13
86
1.52
0.66
1.2
1.3
—
—
—
0
0
7
44
1.60
0.65
1.6
1.2
—
—
—
0
0
25
190
1.33
0.63
7.8
4.5
—
—
—
0
0
18
130
1.39
0.61
1.5
1.5
—
—
—
0
0
5
30
1.67
0.61
1.8
1.8
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
10
64
1.57
0.58
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
3.0
—
70.2
—
0
13
6
35
1.72
0.57
1.7
2.0
11.1
8.5
mg/l
—
6
30
16
218
0.73
0.57
1.0
1.1
0.9
0.9
u/ml
—
6
95
72
629
1.16
0.54
1.4
1.3
—
—
—
0
0
6
38
1.58
0.54
5.7
3.4
—
—
—
0
0
45
378
1.20
0.53
4.3
3.5
—
—
—
0
0
13
91
1.44
0.53
1.3
1.9
—
—
—
0
0
10
66
1.52
0.52
1.2
1.3
—
—
—
0
0
50
425
1.19
0.52
3.5
3.8
0.6
0.7
%
0.11
13
77
9
63
1.43
0.52
1.4
1.4
0.8
0.9
g/l
—
9
63
12
169
0.71
0.52
1.5
1.1
—
—
—
0
0
35
290
1.22
0.48
1.3
1.7
—
—
—
0
0
7
46
1.53
0.48
5.7
1.8
—
—
—
0
0
7
46
1.53
0.48
1.0
1.1
—
—
—
0
0
49
420
1.18
0.48
3.5
4.2
0.1
1.1
%
0.50
13
76
10
143
0.70
0.48
3.3
2.9
25.0
24.4
mmol/l
—
10
133
61
693
0.87
0.45
1.5
1.3
—
—
—
0
0
24
192
1.26
0.45
1.0
1.1
—
—
—
0
0
24
192
1.26
0.45
1.0
1.1
—
—
—
0
0
39
330
1.19
0.44
1.7
1.7
—
—
—
0
0
12
86
1.40
0.44
2.7
2.3
—
—
—
0
0
51
443
1.16
0.43
3.4
4.1
0.1
0.1
%
0.16
15
94
20
158
1.27
0.42
1.3
1.3
316.0
345.2
ug/g
—
9
80
0
15
0.00
0.41
0.0
3.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.3
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
205.5
152.9
iu/ml
—
5
34
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
53
466
1.15
0.40
3.4
4.0
0.6
0.9
%
0.77
16
107
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
9
66
1.37
0.38
1.0
1.0
—
—
—
0
0
9
66
1.37
0.38
1.6
1.2
—
—
nmol/l
—
0
0
71
783
0.90
0.35
1.6
1.7
—
—
—
0
0
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
10
134
0.74
0.35
1.5
1.2
—
—
—
0
0
27
227
1.20
0.35
2.5
2.2
—
—
—
0
0
21
253
0.83
0.33
1.0
1.1
3.1
1.5
u/ml
—
8
99
7
56
1.25
0.29
1.6
1.2
12.5
12.2
u/l
—
7
47
15
184
0.81
0.29
1.1
1.5
—
—
—
0
0
8
66
1.21
0.26
2.0
1.2
—
—
—
0
0
8
67
1.20
0.26
1.4
1.3
—
—
—
0
0
27
236
1.15
0.24
1.9
1.9
3.8
4.9
iu/l
—
8
101
24
274
0.87
0.23
1.1
1.5
57.3
100.0
pmol/l
0.55
24
266
25
219
1.15
0.22
2.2
2.9
7.4
7.4
ph
—
7
25
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.1
—
0
5
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.9
—
1.2
—
0
13
0
13
0.00
0.21
0.0
2.4
—
—
—
0
0
27
242
1.12
0.18
1.9
2.2
0.3
0.1
e6/l
0.31
27
229
13
153
0.85
0.18
2.7
3.0
—
—
—
0
0
55
513
1.08
0.18
2.2
2.2
3.8
4.2
e9/l
1.10
45
454
14
119
1.18
0.17
1.1
1.0
—
—
—
0
0
10
83
1.21
0.15
1.3
1.9
—
—
—
0
0
39
418
0.93
0.14
1.8
1.9
—
—
—
0
0
137
1327
1.04
0.13
1.4
1.4
—
—
—
0
0
48
452
1.07
0.13
4.3
3.1
—
—
—
0
0
44
465
0.94
0.11
1.4
1.3
—
—
—
0
0
25
232
1.08
0.10
1.1
1.3
—
—
—
0
0
30
320
0.94
0.10
1.2
1.2
15.1
12.5
u/l
0.37
22
261
5
46
1.09
0.09
1.0
1.5
—
—
—
0
0
629
6254
1.03
0.09
3.4
3.0
1.2
1.2
mmol/l
0.85
604
5997
59
566
1.05
0.09
1.2
1.3
212.2
167.4
u/ml
0.16
53
527
13
116
1.12
0.09
1.1
1.8
—
—
—
0
0
10
88
1.14
0.08
1.1
1.1
—
—
—
0
0
7
68
1.03
0.08
1.0
1.6
—
—
—
0
0
7
68
1.03
0.08
1.4
1.4
—
—
—
0
0
7
68
1.03
0.08
1.4
1.4
—
—
—
0
0
7
68
1.03
0.08
1.4
1.4
—
—
—
0
0
7
68
1.03
0.08
1.4
1.4
—
—
—
0
0
24
226
1.06
0.06
1.9
2.1
—
—
—
0
0
286
2878
0.99
0.03
2.3
2.1
—
—
—
0
0
37
361
1.03
0.02
1.2
1.3
—
—
—
0
0
29
285
1.02
0.00
1.4
1.4
0.6
0.4
nmol/l
0.28
22
236
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
6.0
—
0.4
—
0
8
23
230
1.00
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
3.7
—
0
5
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
15.8
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
9
95
0.95
0.00
2.8
2.5
—
—
—
0
0
8
80
1.00
0.00
1.0
1.1
—
—
—
0
0
5
50
1.00
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.4
—
—
—
0
0
8
84
0.95
0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
262.7
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
41.2
—
0
6
0
6
0.00
0.00
0.0
1.2
—
81.5
—
0
6
0
5
0.00
0.00
0.0
2.0
—
19.4
—
0
5

Mortality – FinRegistry

Association

Association between endpoint O15_MATERN_INFECT_ELSEWHERE and mortality.

Females

Parameter HR [95% CI] p-value
O15_MATERN_INFECT_ELSEWHERE 2.082 [1.65, 2.62] < 0.001
Birth year 0.994 [0.98, 1.0] 0.195

During the follow-up period (1.1.1998 — 31.12.2019), 91 out of 5032 females with O15_MATERN_INFECT_ELSEWHERE died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_MATERN_INFECT_ELSEWHERE.

N-year risk Females Males
1 0.203% No data
5 1.09% No data
10 2.947% No data
15 5.379% No data
20 9.454% No data

Relationships between endpoints

Index endpoint: O15_MATERN_INFECT_ELSEWHERE – Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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