Fetal death of unspecified cause

P16_FETAL_DEATH_UNSP_CAUSE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P95
  • Cause of death: ICD-10 P95

2 out of 7 registries used, show all original rules.

60

4. Check minimum number of events

None

60

5. Include endpoints

None

60

6. Filter based on genotype QC (FinnGen only)

60

Control definitions (FinnGen only)

Control exclude
P16_OTH_DISORD_ORIGINA_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P9
Name in latin
Mors fetus causa non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 391 384 -
Only index persons 380 378 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population 31.05 31.27 -
Only index persons 31.20 31.27 -

-FinnGen-

Key figures

All Female Male
Number of individuals 60 60 -
Unadjusted period prevalence (%) 0.02 0.02 -
Median age at first event (years) 31.78 31.78 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
54
Matched controls
539
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P95
ICD-10 Finland
Fetal death of unspecified cause
+∞
77.3
54
*
G02CB01
ATC
bromocriptine; systemic
29.6
17.1
23
13
O36.4
ICD-10 Finland
Maternal care for intrauterine death
101.3
14.4
15
*
Z39.2
ICD-10 Finland
Routine postpartum follow-up
7.8
10.3
28
65
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
7.1
9.4
27
66
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
16.6
8.4
13
10
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
8.2
6.8
15
24

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
12
5.42
2.46
17.8
5.3
—
—
—
0
0
40
289
2.15
2.03
3.8
3.4
—
17.4
—
0
5
5
11
4.85
1.98
2.0
1.2
—
—
—
0
0
11
51
2.42
1.62
3.3
2.0
—
—
—
0
0
5
15
3.53
1.55
3.0
3.3
—
—
—
0
0
6
21
3.06
1.55
5.3
3.0
—
—
—
0
0
6
21
3.06
1.55
20.8
4.0
1.3
1.9
mmol/l
—
6
21
9
38
2.60
1.53
1.1
1.2
—
—
—
0
0
17
98
2.03
1.51
4.1
2.4
—
—
—
0
0
5
18
2.93
1.31
27.8
4.8
—
—
—
0
0
40
327
1.67
1.02
4.0
3.5
—
—
—
0
0
8
140
0.51
0.99
8.9
5.3
—
—
—
0
0
8
43
1.99
0.92
3.3
3.9
4.4
4.7
pmol/l
—
8
36
17
115
1.67
0.89
3.4
1.2
2.4
2.1
g/l
0.15
11
79
11
65
1.85
0.89
3.3
2.7
9.0
155.1
ng/l
—
5
27
55
504
2.09
0.87
3.5
3.4
1.5
1.6
mmol/l
0.76
55
483
8
135
0.53
0.86
3.0
1.7
—
—
—
0
0
22
162
1.57
0.83
5.1
4.2
37.9
36.7
g/l
0.70
22
155
18
127
1.60
0.80
2.1
1.9
—
—
—
0
0
14
93
1.66
0.78
2.3
3.3
—
—
—
0
0
12
77
1.70
0.75
6.6
3.4
—
—
—
0
0
26
320
0.67
0.75
4.2
2.5
—
—
—
0
0
15
207
0.63
0.75
20.4
7.6
0.0
0.0
e9/l
0.48
15
172
55
506
2.04
0.74
3.8
3.5
3.0
3.0
mmol/l
0.09
55
481
16
112
1.58
0.73
1.8
1.7
—
—
—
0
0
52
477
1.67
0.63
16.3
12.1
331.3
331.7
g/l
0.12
52
477
5
30
1.73
0.63
1.0
1.1
—
—
—
0
0
8
52
1.62
0.62
1.4
1.6
1672.0
1068.2
nmol/l
—
8
41
60
580
+∞
0.61
25.0
14.6
4.5
4.5
e12/l
0.40
60
571
60
580
+∞
0.61
24.9
14.6
29.7
30.1
pg
0.91
60
575
60
580
+∞
0.61
25.0
14.7
6.4
6.5
e9/l
0.30
60
568
60
581
+∞
0.61
25.2
14.7
132.8
134.1
g/l
0.38
60
575
60
579
+∞
0.61
24.9
14.6
89.5
90.5
fl
1.08
60
574
6
34
1.85
0.61
2.3
5.6
—
—
—
0
0
52
483
1.57
0.52
4.6
4.9
1.7
4.1
mu/l
0.50
52
463
19
148
1.42
0.52
2.8
2.3
—
—
—
0
0
9
129
0.64
0.50
20.9
6.8
—
—
—
0
0
18
223
0.72
0.47
2.3
1.9
—
—
—
0
0
7
50
1.45
0.47
2.4
1.3
—
—
—
0
0
12
87
1.47
0.46
1.5
1.3
—
—
—
0
0
14
106
1.42
0.44
1.9
2.3
—
—
—
0
0
22
182
1.33
0.41
2.7
2.7
—
—
—
0
0
9
122
0.69
0.40
2.8
1.8
114.6
119.6
u/l
—
9
116
9
69
1.36
0.39
1.0
1.3
33.5
28.2
iu/l
—
9
60
5
36
1.42
0.39
21.8
17.4
—
1.1
—
0
10
45
414
1.35
0.38
4.1
4.4
13.5
14.1
pmol/l
0.97
45
399
6
42
1.48
0.37
4.7
2.0
2.6
4.1
e9/l
—
6
37
32
284
1.27
0.34
3.8
2.8
62.0
60.8
ug/l
0.04
32
269
15
120
1.33
0.34
2.7
5.1
1.0
1.0
inr
—
5
44
10
75
1.40
0.32
1.8
1.8
—
—
—
0
0
7
53
1.36
0.32
1.1
1.0
—
—
—
0
0
51
482
1.39
0.31
3.6
3.1
1.2
1.2
mmol/l
0.11
51
458
27
241
1.22
0.26
6.8
6.0
11.6
9.5
umol/l
0.57
27
231
17
144
1.25
0.25
13.4
5.9
—
—
—
0
0
5
38
1.34
0.24
1.4
1.6
—
—
—
0
0
45
425
1.24
0.22
4.7
3.9
37.3
37.3
mmol/mol
0.01
45
411
0
11
0.00
0.21
0.0
4.6
—
58.6
—
0
11
0
11
0.00
0.21
0.0
4.3
—
4.6
—
0
11
0
10
0.00
0.21
0.0
2.1
—
5.0
—
0
10
0
10
0.00
0.21
0.0
2.1
—
10.2
—
0
10
0
10
0.00
0.21
0.0
2.1
—
7.5
—
0
10
0
10
0.00
0.21
0.0
5.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
6
47
1.31
0.21
5.8
2.0
2.4
2.5
g/l
—
6
42
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
14
119
1.23
0.20
4.9
2.7
32.8
13.0
ng/l
—
5
48
7
59
1.21
0.19
2.1
2.0
—
—
—
0
0
11
129
0.82
0.16
1.4
1.5
1.1
1.5
mmol/l
2.43
11
115
53
514
1.27
0.16
20.5
10.0
17.2
16.8
mg/l
0.05
39
381
24
261
0.87
0.15
14.0
6.0
0.1
0.2
e9/l
2.99
24
245
15
132
1.18
0.15
3.5
2.1
—
—
—
0
0
14
155
0.87
0.10
2.4
1.6
86.7
100.8
pmol/l
—
9
94
6
53
1.15
0.09
2.7
1.2
—
—
—
0
0
6
54
1.12
0.09
1.5
1.4
—
—
—
0
0
5
63
0.78
0.08
1.6
1.2
—
—
—
0
0
11
98
1.15
0.08
5.2
2.3
7.1
8.0
mmol/l
0.23
11
84
7
67
1.05
0.08
1.1
1.1
—
—
—
0
0
7
81
0.85
0.07
1.3
1.5
483.9
459.5
pmol/l
—
7
75
24
251
0.93
0.05
13.1
5.8
0.0
0.0
e9/l
0.36
24
230
24
250
0.93
0.04
13.1
5.9
0.5
0.5
e9/l
0.31
24
230
22
229
0.94
0.03
14.6
5.6
0.6
0.7
%
0.48
22
215
23
239
0.94
0.03
2.3
2.3
—
—
—
0
0
18
172
1.07
0.02
14.2
4.2
1.2
1.2
mmol/l
0.35
18
159
25
242
1.06
0.02
13.0
5.6
33.6
29.8
%
1.22
25
232
49
484
1.07
0.01
22.0
8.6
139.6
139.8
mmol/l
0.24
49
472
15
144
1.06
0.01
6.2
2.3
47.3
54.1
u/l
0.40
15
138
10
97
1.04
0.00
4.5
2.2
—
—
—
0
0
49
487
1.03
0.00
22.8
8.7
3.8
3.9
mmol/l
0.58
49
474
26
261
0.99
0.00
12.3
5.8
1.9
1.9
e9/l
0.04
26
243
23
233
0.98
0.00
14.2
5.8
8.6
8.1
%
0.29
23
222
13
125
1.05
0.00
1.4
1.3
3.6
7.0
u/ml
—
6
57
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
6.7
—
1.3
—
0
7
0
7
0.00
0.00
0.0
15.7
—
1645.7
—
0
7
0
5
0.00
0.00
0.0
10.0
—
0.7
—
0
5
5
49
1.02
0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
14.4
—
946.9
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
64
0.93
0.00
3.2
2.0
—
—
—
0
0
9
88
1.03
0.00
1.2
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
90.8
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
9.8
—
0
5
0
5
0.00
0.00
0.0
4.0
—
7.9
—
0
5
7
77
0.90
0.00
1.6
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_FETAL_DEATH_UNSP_CAUSE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_FETAL_DEATH_UNSP_CAUSE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_FETAL_DEATH_UNSP_CAUSE – Fetal death of unspecified cause

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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