Benign neoplasm: Liver/bile ducts

CD2_BENIGN_LIVE_BILE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

1003

6. Filter based on genotype QC (FinnGen only)

977

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4652 3169 1446
Only index persons 4204 2945 1259
Unadjusted period prevalence (%)
Whole population 0.07 0.09 0.04
Only index persons 0.09 0.11 0.05
Median age at first event (years)
Whole population 53.05 49.88 59.76
Only index persons 51.67 48.81 58.37

-FinnGen-

Key figures

All Female Male
Number of individuals 977 711 266
Unadjusted period prevalence (%) 0.22 0.25 0.12
Median age at first event (years) 53.28 49.74 62.74

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1003
Matched controls
10030
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
53.7
307.7
226
54
D13.4
ICD-10 Finland
Benign neoplasm: Liver
4503599627370496.0
307.7
887
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
26.3
263.9
191
89
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
18.9
159.8
131
79
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
15.2
112.4
102
74
D13.5
ICD-10 Finland
Benign neoplasm: Extrahepatic bile ducts
+∞
108.3
102
*
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
32.6
107.6
70
23
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.2
88.7
214
498
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
16.6
61.0
52
33
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
47.6
497
2753
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
7.9
43.2
61
82
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.5
41.8
71
117
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
39.6
270
1196
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
38.7
187
686
D18.0
ICD-10 Finland
Haemangioma, any site
6.7
35.7
58
91
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
29.7
337
1847
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.8
27.6
161
648
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.0
27.1
134
493
UJF32
NOMESCO Finland
Coloscopy
2.1
22.4
279
1558
JN3AD
NOMESCO Finland
Abdominal CT examination
2.6
21.4
137
575
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
16.8
19.7
31
19
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.5
18.6
67
203
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.3
18.5
48
115
N02AX02
ATC
tramadol; systemic, rectal
1.8
18.2
434
2971
K76.9
ICD-10 Finland
Liver disease, unspecified
6.6
18.0
29
45
K76.89
ICD-10 Finland
Other specified diseases of liver
20.5
17.8
26
13
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
17.0
291
1791
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.4
16.8
43
102
J01MA02
ATC
ciprofloxacin; systemic
1.8
16.0
381
2582
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
6.0
15.8
28
48
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
15.7
222
1278
A02BC02
ATC
pantoprazole; systemic
1.8
15.6
671
5350
A02BC05
ATC
esomeprazole; systemic
1.7
15.3
418
2935
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
4.7
15.3
35
76
WX402
NOMESCO Finland
General anaesthesia
1.9
14.8
230
1363
K76.80
ICD-10 Finland
Hepatic cyst
11.5
14.8
27
24
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
14.4
14.6
24
17
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
14.3
238
1442
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.3
14.0
54
171
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
13.8
264
1666
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.1
13.7
138
701
JN4CD
NOMESCO Finland
Very extensive body CT
3.8
13.3
41
112
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
13.1
64
233
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
11.1
13.1
24
22
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
50.7
12.9
15
*
JJB71
NOMESCO Finland
Laparoscopic resection of liver
50.7
12.9
15
*
21150
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Hepatis
+∞
12.5
12
*
JKA20
NOMESCO Finland
Cholecystectomy
4.0
12.1
34
87
A02BC01
ATC
omeprazole; systemic
1.7
11.8
272
1797
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
12.7
11.7
20
16
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
15.2
11.3
18
12
A02BC03
ATC
lansoprazole; oral
1.7
11.3
281
1892
R07.0
ICD-10 Finland
Pain in throat
2.3
11.2
84
377
JJB50
NOMESCO Finland
Excision of segments V, VI, VII and VIII of liver
43.8
10.9
13
*
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
18.0
10.7
16
9
J01DB01
ATC
cefalexin; oral
1.8
10.7
826
7269
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
13.1
10.7
18
14
R06.0
ICD-10 Finland
Dyspnoea
1.7
10.4
252
1680
Z3231
NOMESCO Finland
Registered nurse
1.7
10.3
260
1752
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
10.1
142
809
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
9.9
146
844
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.3
9.8
78
359
D01
ICPC
Abdominal pain/cramps general
1.9
9.8
125
688
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
26.3
9.8
13
5
K83.0
ICD-10 Finland
Cholangitis
5.0
9.8
21
43
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
9.8
128
711
130
Kela drug reimbursment
Malignant tumour
2.3
9.8
78
360
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
9.6
400
3025
R4110
NOMESCO Finland
Physiotherapy
1.6
9.4
258
1768
P01AB01
ATC
metronidazole; oral, rectal
1.5
9.4
413
3154
JN1AE, ,
SPAT
2.7
9.2
48
181
K30
ICD-10 Finland
Functional dyspepsia
1.9
9.2
122
681
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
9.1
100
523
N02BE01
ATC
paracetamol; systemic, rectal
1.8
9.1
875
7924
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
18.8
8.9
13
7
H53.1
ICD-10 Finland
Subjective visual disturbances
2.3
8.9
71
328
B01AB04
ATC
dalteparin; parenteral
2.5
8.9
55
227
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
8.8
153
929
JN3AE, ,
SPAT
2.8
8.6
42
153
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
8.5
358
2695
R01AD58
ATC
fluticasone, combinations; nasal
1.6
8.4
261
1836
XKD00
NOMESCO Finland
Uroflowmetry
1.9
8.4
108
597
B01AB05
ATC
enoxaparin; parenteral
1.5
8.3
282
2025
UJK02
NOMESCO Finland
ERCP
3.3
8.3
30
92
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.1
347
2613
R51.80
ICD-10 Finland
Headache
1.7
8.1
168
1069
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
3.8
8.1
24
64
JJB30
NOMESCO Finland
Excision of two segments of liver
33.6
8.1
10
*
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
11.8
8.1
14
12
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
11.8
8.1
14
12
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
8.1
242
1688
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
22.2
8.0
11
5
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.1
7.9
71
344
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.8
196
1311
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
7.8
103
575
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
7.7
180
1180
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
7.7
217
1489
UJK12
NOMESCO Finland
Peroral cholangioscopy
45.3
7.7
9
*
K83.1
ICD-10 Finland
Obstruction of bile duct
4.6
7.7
18
40
Z3226
NOMESCO Finland
Physiotherapist
1.7
7.7
171
1109
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.4
7.6
26
77
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
7.5
130
786
UKC02
NOMESCO Finland
Cystoscopy
1.8
7.4
122
729
Z71.8
ICD-10 Finland
Other specified counselling
1.5
7.4
305
2275
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
9.4
7.3
14
15
R30.0
ICD-10 Finland
Dysuria
2.4
7.3
47
198
K86.2
ICD-10 Finland
Cyst of pancreas
5.8
7.2
19
33
JJB10
NOMESCO Finland
Atypcal resection of liver
15.9
7.2
11
7
N03AX16
ATC
[U] pregabalin
1.6
7.2
215
1495
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.6
7.2
23
65
J01MA12
ATC
levofloxacin; systemic
1.6
7.1
158
1022
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
7.1
307
2305
D06
ICPC
Abdominal pain localized other
1.9
7.0
84
453
SPAT1360
SPAT
Extensive global examination
2.2
7.0
61
293
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
4.4
7.0
17
39
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
13.9
6.9
11
8
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.4
6.9
46
197
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.2
6.8
17
28
R01AD09
ATC
mometasone; nasal
1.4
6.8
457
3722
A10AB05
ATC
insulin aspart; parenteral
2.0
6.6
69
355
C08CA01
ATC
amlodipine; oral
1.5
6.6
294
2216
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
2.8
6.6
32
117
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.4
6.6
44
189
D02
ICPC
Abdominal pain epigastric
2.1
6.5
64
322
N03AX12
ATC
[U] gabapentin; oral
1.6
6.5
154
1012
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
70.3
6.4
7
*
JN3GE
NOMESCO Finland
Intraoperative ultrasound examination of abdomen
70.3
6.4
7
*
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
3.0
6.4
27
91
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.0
6.4
65
331
M54
ICD-10 Finland
Dorsalgia
1.7
6.4
122
759
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
4.1
6.4
17
42
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
6.3
124
776
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
11.1
6.3
11
10
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
6.3
185
1280
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.2
504
4213
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
26.8
6.2
8
*
XX9KE
NOMESCO Finland
Ultrasound examination with contrast
26.8
6.2
8
*
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.2
6.2
51
239
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
6.2
90
517
R53
ICD-10 Finland
Malaise and fatigue
1.5
6.2
220
1583
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
3.2
6.2
24
77
M03BX02
ATC
tizanidine; oral
1.4
6.2
607
5240
A02BA02
ATC
ranitidine; systemic
1.6
6.2
166
1124
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.2
322
2495
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.8
6.1
90
519
R06AE07
ATC
cetirizine; oral
1.4
6.1
425
3460
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
6.1
97
573
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
2.4
6.1
42
183
JJA20
NOMESCO Finland
Open biopsy of liver
10.1
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
314
707
6.01
139.61
2.5
4.2
2.67
24.50
ug/l
1.24
215
576
186
254
8.76
133.16
2.1
3.3
30.19
1156.75
u/ml
0.98
164
218
741
4135
4.03
86.70
6.8
5.8
10.49
10.54
umol/l
0.05
714
3921
75
59
13.66
78.46
1.3
1.4
—
—
—
0
0
281
896
3.97
76.59
3.9
2.5
5.20
6.79
umol/l
2.15
251
771
103
133
8.52
76.09
2.0
3.7
118.68
2208.27
u/ml
0.60
95
126
237
718
4.01
68.83
2.5
2.2
0.23
0.22
g/l
1.59
230
678
596
3261
3.04
64.13
5.6
4.5
36.17
36.17
g/l
0.00
564
3058
877
6266
4.18
55.12
9.4
7.1
80.58
76.39
u/l
2.46
845
5900
411
1970
2.84
54.28
5.6
3.5
96.60
93.98
%
1.25
402
1904
572
3314
2.69
50.99
12.3
11.7
1.15
1.18
inr
0.29
125
1032
450
2529
2.41
39.80
3.2
2.5
57.06
60.24
u/l
0.49
415
2348
478
2798
2.35
38.05
4.1
3.2
31.69
30.24
u/l
0.60
462
2660
93
221
4.54
36.43
1.4
1.1
52.22
83.16
titre
—
9
19
89
231
4.13
31.02
1.3
1.2
—
835.00
—
0
8
648
4556
2.19
30.23
6.4
4.4
6.57
6.55
mmol/l
0.06
620
4206
574
3898
2.10
28.69
2.8
2.4
—
—
—
0
0
344
1928
2.19
28.47
2.6
2.1
—
—
—
0
0
410
2559
2.02
24.71
2.6
2.1
—
—
—
0
0
745
5785
2.12
23.55
4.4
3.0
64.02
42.93
u/l
8.22
719
5462
164
726
2.51
23.01
3.4
2.4
31.04
37.64
u/l
1.03
137
608
137
565
2.65
22.21
9.1
7.4
8.15
8.81
mmol/l
0.46
131
538
641
4774
1.95
22.03
8.5
8.8
4.39
4.01
e9/l
3.50
558
4199
202
1005
2.26
21.68
3.0
2.2
23.71
23.02
%
0.30
185
864
213
1089
2.21
21.36
3.0
2.2
2.47
2.38
g/l
1.09
199
1010
227
1192
2.17
21.29
3.0
2.2
13.90
13.56
umol/l
0.32
218
1109
765
6124
2.05
20.48
4.4
3.9
12.15
10.98
mm/h
1.35
719
5700
951
8382
3.60
20.10
17.0
12.4
23.57
21.42
mg/l
1.12
828
6550
526
3756
1.84
19.68
9.1
6.2
1.22
1.22
mmol/l
0.09
474
3192
576
4253
1.83
19.09
6.0
5.6
2.37
1.93
e9/l
0.59
504
3821
562
4124
1.83
18.96
6.0
5.6
0.58
0.55
e9/l
0.88
480
3616
562
4133
1.82
18.73
6.0
5.6
0.04
0.04
e9/l
0.66
481
3626
577
4279
1.82
18.68
6.2
6.0
0.19
0.18
e9/l
0.13
495
3807
947
8420
3.23
17.80
18.7
13.6
139.60
139.64
mmol/l
0.17
937
8201
475
3376
1.77
17.26
8.1
5.5
1.22
1.22
mmol/l
0.04
440
3090
947
8443
3.18
17.24
18.8
13.7
3.93
3.95
mmol/l
1.62
936
8209
529
3880
1.77
17.22
6.0
6.1
—
—
—
0
0
168
859
2.15
16.54
10.4
6.8
105.23
104.34
mmol/l
2.04
168
859
285
1760
1.87
16.36
1.7
1.4
2.16
2.28
g/l
0.66
193
1101
531
3968
1.72
15.58
6.2
5.5
57.72
56.88
%
0.98
506
3740
536
4016
1.72
15.57
6.4
5.8
28.55
28.55
%
0.00
510
3790
519
3875
1.70
15.09
6.3
5.7
2.71
2.80
%
0.45
493
3641
521
3894
1.70
15.09
6.6
6.0
7.95
8.30
%
2.20
495
3666
201
1134
1.97
15.03
1.2
1.2
—
—
—
0
0
210
1203
1.94
15.02
1.5
1.3
545.78
521.71
titre
0.06
45
257
503
3729
1.70
14.98
6.3
5.7
0.65
0.67
%
0.38
473
3489
678
5453
1.75
14.93
4.9
4.1
410.57
1692.93
e6/l
—
7
69
196
1102
1.97
14.79
2.0
2.4
117.84
109.63
ug/g
0.15
149
867
133
647
2.22
14.76
1.4
1.4
—
—
—
0
0
118
547
2.31
14.69
4.0
3.6
89.99
79.06
ng/l
0.53
99
497
312
2049
1.76
14.28
1.3
1.3
0.59
1.88
u/ml
3.44
88
561
190
1088
1.92
13.49
1.5
1.6
—
—
—
0
0
389
2751
1.68
13.40
4.8
3.5
37.11
86.91
e6/l
1.88
261
1853
169
932
1.98
13.39
7.2
5.2
1.05
1.02
mmol/l
0.54
156
860
199
1160
1.89
13.37
3.5
2.8
2.76
3.06
e6/l
0.16
104
596
697
5730
1.71
13.32
4.8
4.1
—
—
—
0
0
292
1917
1.74
13.21
2.2
1.7
1.02
1.03
mg/l
0.03
228
1445
208
1238
1.86
13.07
2.9
2.6
1.28
1.07
e6/l
0.19
110
669
464
3450
1.64
13.04
2.6
2.0
—
—
—
0
0
76
306
2.61
12.82
2.6
1.8
22.97
21.19
s
0.50
66
268
306
2050
1.71
12.80
3.6
2.9
—
—
—
0
0
309
2078
1.70
12.73
3.8
2.9
0.29
0.41
e6/l
0.58
213
1541
330
2269
1.68
12.46
4.1
3.0
51.74
93.38
e6/l
0.55
240
1716
103
488
2.24
12.14
2.1
1.7
1.18
1.49
g/l
1.15
97
449
179
1040
1.88
12.06
1.4
1.3
—
—
—
0
0
160
899
1.93
11.93
1.4
1.3
—
—
—
0
0
286
1916
1.69
11.81
4.0
3.9
—
—
—
0
0
217
1375
1.74
10.87
3.3
3.5
1536.31
286.82
ng/l
0.60
151
963
290
2000
1.63
10.50
2.5
2.1
2.79
2.88
mg/l
0.26
246
1714
138
773
1.91
10.33
9.7
7.7
0.37
1.11
mmol/l
1.59
116
619
19
20
9.66
9.79
1.3
4.1
—
—
—
0
0
446
3444
1.53
9.72
2.8
2.3
72.62
76.10
nmol/l
2.01
410
3129
406
3072
1.54
9.71
2.1
1.9
100.54
96.45
pmol/l
0.83
227
1621
112
601
1.97
9.49
8.6
7.1
1.36
1.32
mmol/l
0.13
112
586
286
2019
1.58
9.21
2.9
2.4
2398.65
5800.76
umol/l
1.20
255
1772
79
376
2.20
9.21
8.0
10.0
—
—
—
0
0
357
2652
1.54
9.16
3.1
3.3
2.36
2.35
mmol/l
1.26
312
2360
953
8899
2.42
8.95
13.7
9.6
29.39
25.48
u/l
6.92
936
8623
374
2831
1.51
8.68
3.3
3.3
26.76
33.71
ng/l
0.53
219
1757
100
537
1.96
8.45
11.9
8.8
—
—
—
0
0
424
3309
1.49
8.41
3.8
3.1
5.90
5.86
ph
0.15
50
289
120
687
1.85
8.36
1.3
1.2
—
—
—
0
0
173
1103
1.69
8.31
2.1
1.9
—
—
—
0
0
98
540
1.90
7.68
1.5
1.4
—
—
—
0
0
489
3997
1.44
7.27
3.8
2.7
111.13
101.49
ug/l
0.51
465
3738
755
6711
1.51
7.09
4.7
4.1
14.53
14.56
pmol/l
0.14
697
6181
45
189
2.45
7.03
3.9
3.9
37.69
32.37
mg/l
0.23
38
152
182
1228
1.59
6.91
4.3
3.1
0.83
0.82
mmol/l
0.45
167
1158
198
1367
1.56
6.80
2.9
2.7
2.46
2.43
mmol/l
1.49
177
1211
67
340
2.04
6.66
1.5
1.6
—
—
—
0
0
276
2057
1.47
6.57
6.9
6.3
—
—
—
0
0
44
189
2.39
6.56
4.0
3.9
43.74
83.34
mg/l
0.60
38
153
258
1899
1.48
6.53
2.7
2.9
1348.00
1053.82
ng/l
0.46
218
1591
31
112
2.82
6.52
1.0
1.0
0.08
0.09
u/ml
—
10
35
252
1848
1.49
6.50
3.6
3.4
—
—
—
0
0
32
118
2.77
6.49
1.0
1.1
5.55
6.51
u/ml
0.09
13
42
296
2242
1.45
6.46
5.5
3.7
7.39
7.40
ph
0.61
42
425
500
4164
1.40
6.38
4.0
3.4
0.00
0.01
estimate
0.80
69
767
495
4117
1.40
6.36
4.1
3.4
0.00
0.00
estimate
0.50
76
830
43
187
2.36
6.25
2.9
3.8
0.90
1.94
ratio
—
5
20
937
8838
1.91
6.21
16.2
11.6
—
—
—
0
0
493
4110
1.39
6.18
5.7
4.6
0.00
0.00
estimate
0.50
72
790
38
159
2.44
6.02
1.0
1.1
1.51
5.03
u/ml
1.56
19
76
854
7877
1.57
5.96
5.7
4.8
1.72
1.97
mu/l
1.01
801
7305
40
175
2.34
5.76
1.2
1.2
—
—
—
0
0
219
1597
1.48
5.73
1.6
1.6
—
—
—
0
0
208
1502
1.49
5.72
4.2
2.7
542.11
539.72
mosm/kgh2o
0.05
173
1291
40
176
2.33
5.69
1.1
1.1
1.95
2.95
u/ml
0.42
17
87
50
243
2.11
5.60
1.5
1.4
312.11
300.44
ug/g
0.13
27
137
36
153
2.40
5.53
1.0
1.1
0.34
0.84
u/ml
1.46
12
62
305
2389
1.40
5.36
2.8
2.7
—
—
—
0
0
115
738
1.63
5.34
2.9
2.5
1.90
1.82
%
0.23
101
655
32
131
2.49
5.33
1.0
1.0
1.37
2.94
u/ml
0.98
14
61
94
574
1.70
5.27
1.3
1.2
—
—
—
0
0
636
5620
1.36
5.09
3.8
3.5
—
—
—
0
0
213
1585
1.44
4.96
3.3
2.5
5.52
7.06
e6/l
0.85
183
1418
15
41
3.70
4.94
2.7
2.9
43466.67
36709.88
ug/l
1.16
15
41
53
279
1.95
4.82
1.8
2.2
1.46
1.48
g/l
0.06
43
242
286
2251
1.38
4.80
2.1
2.1
161.89
202.64
u/l
0.47
271
2129
49
253
1.98
4.71
9.4
4.6
—
—
—
0
0
93
584
1.65
4.71
1.3
1.3
131.51
199.71
u/ml
0.73
86
543
34
152
2.28
4.70
1.0
1.1
0.32
1.32
u/ml
1.64
14
76
58
318
1.87
4.68
1.4
1.5
—
5.79
—
0
7
66
377
1.80
4.68
2.7
2.2
—
—
—
0
0
95
601
1.64
4.68
5.4
3.5
1.99
1.93
mmol/l
0.09
84
494
84
515
1.69
4.66
2.1
2.9
127.20
166.15
ng/l
0.61
77
468
179
1305
1.45
4.63
1.7
1.7
1113.88
1206.78
nmol/l
0.73
139
998
230
1764
1.39
4.48
1.7
1.5
18.90
20.85
nmol/l
1.40
198
1522
85
532
1.65
4.37
3.4
2.5
69.60
72.14
e9/l
0.32
66
403
16
51
3.17
4.22
1.1
1.0
—
—
—
0
0
133
933
1.49
4.18
1.8
1.6
—
—
—
0
0
429
3646
1.31
4.17
9.6
8.7
0.00
0.00
e9/l
0.28
337
3013
88
567
1.61
4.05
2.0
2.3
6.88
6.52
ug/l
0.06
78
499
284
2288
1.34
4.00
3.7
3.1
7.94
7.61
mmol/l
0.56
253
1959
30
138
2.21
3.92
1.1
1.1
—
—
—
0
0
30
139
2.19
3.86
3.8
2.1
—
—
—
0
0
29
133
2.22
3.83
1.1
1.0
—
—
—
0
0
15
49
3.09
3.81
1.1
1.0
—
—
—
0
0
90
592
1.57
3.81
2.4
2.6
4.27
6.48
e9/l
1.15
65
498
299
2449
1.31
3.71
1.4
1.5
—
—
—
0
0
44
239
1.88
3.71
9.5
4.0
1.13
1.33
mmol/l
1.22
44
233
14
39
3.63
3.71
2.1
1.9
2.02
7.45
nmol/l
—
9
29
88
583
1.56
3.62
3.1
3.4
4.51
4.56
pmol/l
0.20
77
510
101
690
1.52
3.62
1.4
1.5
—
—
—
0
0
195
1509
1.36
3.54
1.3
1.3
19.26
13.13
u/ml
0.37
82
605
203
1582
1.36
3.53
1.3
1.3
25.05
32.17
iu/ml
0.44
54
512
968
9387
1.89
3.50
27.0
18.4
40.09
40.13
%
0.07
930
8868
790
7370
1.34
3.49
20.7
14.9
14.70
14.69
%
0.01
785
7257
113
797
1.47
3.47
1.9
2.0
395.67
379.23
nmol/l
0.31
96
740
30
146
2.09
3.44
4.6
4.3
—
—
—
0
0
968
9394
1.87
3.39
26.5
18.4
267.00
257.43
e9/l
3.73
948
9188
72
463
1.60
3.37
2.3
2.3
—
—
—
0
0
968
9397
1.86
3.34
26.5
18.3
90.29
90.70
fl
2.19
960
9285
968
9399
1.86
3.30
26.5
18.3
29.96
30.19
pg
4.19
960
9286
968
9400
1.85
3.29
26.6
18.3
4.49
4.49
e12/l
0.04
950
9174
30
149
2.04
3.28
1.5
1.2
2.07
5.69
u/ml
1.16
14
54
968
9401
1.85
3.27
26.6
18.4
7.08
6.65
e9/l
7.50
950
9168
968
9405
1.84
3.21
26.7
18.4
133.86
134.95
g/l
1.66
961
9288
75
494
1.56
3.19
1.3
1.2
—
—
—
0
0
50
297
1.72
3.18
1.3
1.2
—
—
—
0
0
266
2187
1.29
3.15
4.6
3.8
17.31
8.84
mg/mmol
1.01
190
1384
68
440
1.59
3.12
7.1
4.9
—
—
—
0
0
799
7504
1.32
3.10
6.4
5.2
39.57
39.08
mmol/mol
0.78
757
7011
47
277
1.73
3.08
1.1
1.1
1.20
5.90
u/ml
—
5
43
38
210
1.84
3.08
2.8
3.0
—
—
—
0
0
106
758
1.45
3.05
5.1
3.7
—
—
—
0
0
254
2084
1.29
3.04
3.9
3.3
936.82
393.49
mg/l
0.66
179
1340
30
154
1.98
3.02
1.1
1.2
—
—
—
0
0
261
2156
1.28
2.96
4.1
3.5
—
—
—
0
0
82
563
1.50
2.90
2.4
2.8
66.72
67.30
g/l
0.31
72
516
66
432
1.56
2.90
3.3
2.1
12.16
11.88
nmol/l
0.09
54
386
45
726
0.60
2.85
5.5
3.5
—
—
—
0
0
47
284
1.69
2.84
2.7
5.3
1.77
1.57
%
0.61
47
267
70
467
1.54
2.84
1.1
1.1
—
122.60
—
0
10
47
289
1.66
2.68
1.7
1.5
1.26
1.20
g/l
0.63
47
272
135
1031
1.36
2.67
1.3
1.4
—
—
—
0
0
5
7
7.17
2.55
8.4
3.1
5.80
8.00
mmol/l
—
5
7
50
318
1.60
2.51
4.4
3.3
25.32
25.38
mmol/l
0.04
50
308
865
8277
1.33
2.48
4.8
4.1
4.70
4.75
mmol/l
0.69
822
7757
85
610
1.43
2.44
3.5
3.2
—
—
—
0
0
41
251
1.66
2.40
3.0
2.6
—
—
—
0
0
35
206
1.72
2.36
2.6
1.8
38.10
38.67
g/l
0.23
29
189
13
52
2.52
2.36
5.8
7.4
—
—
—
0
0
833
7946
1.29
2.33
4.3
3.7
1.39
1.26
mmol/l
5.39
775
7364
38
230
1.68
2.33
1.3
1.2
1.50
2.74
u/ml
—
6
28
9
28
3.23
2.31
3.4
2.6
—
—
—
0
0
42
262
1.63
2.30
3.6
3.3
0.35
0.26
g/l
0.27
23
100
19
92
2.09
2.28
1.1
1.2
—
—
—
0
0
11
40
2.77
2.28
1.5
2.3
3619.27
678.45
u/ml
0.47
11
40
7
18
3.91
2.25
2.9
4.6
—
—
—
0
0
29
164
1.79
2.25
1.7
1.5
—
—
—
0
0
214
1783
1.25
2.22
4.4
3.6
1.02
1.02
kg/l
0.09
30
250
10
35
2.88
2.21
40.7
23.5
6.66
7.39
ug/l
—
10
29
123
956
1.33
2.19
1.4
1.4
—
—
—
0
0
6
14
4.30
2.15
1.8
1.9
—
—
—
0
0
9
30
3.02
2.15
1.2
1.5
73.33
75.30
nmol/24h
—
9
30
81
591
1.40
2.14
1.4
1.3
25.41
28.31
iu/l
0.36
68
510
110
844
1.34
2.14
1.4
1.4
—
—
—
0
0
839
8032
1.27
2.12
4.8
4.2
5.90
5.82
mmol/l
0.94
788
7407
9
31
2.92
2.07
1.2
1.2
—
—
—
0
0
858
8244
1.28
2.05
4.8
4.1
1.46
1.50
mmol/l
2.26
804
7690
13
56
2.34
2.05
1.2
1.3
—
—
—
0
0
59
410
1.47
2.04
1.1
1.1
—
—
—
0
0
28
162
1.75
2.03
1.3
1.2
188.15
258.33
u/ml
1.37
13
104
41
263
1.58
2.03
2.2
2.0
4.34
2.53
ug/l
0.21
33
236
125
985
1.31
2.03
3.0
2.9
0.80
0.71
ug/l
0.45
91
648
50
336
1.51
2.03
2.8
3.0
—
—
—
0
0
8
26
3.09
2.01
1.0
1.1
—
—
—
0
0
252
2163
1.22
1.98
1.7
1.6
1.55
1.36
mmol/l
2.10
228
1851
26
149
1.76
1.96
1.5
1.4
102.80
112.90
u/ml
—
7
30
38
243
1.59
1.92
2.5
1.9
10.19
10.24
g/l
0.03
32
225
19
99
1.94
1.91
1.1
1.2
0.50
0.55
nmol/l
0.50
19
94
12
52
2.32
1.88
1.1
1.1
1.64
0.30
u/ml
—
5
19
15
72
2.10
1.87
1.6
1.6
—
—
—
0
0
9
34
2.66
1.86
1.0
1.3
—
—
—
0
0
16
80
2.02
1.80
1.4
1.2
—
—
—
0
0
8
29
2.77
1.79
1.8
1.2
—
—
—
0
0
8
29
2.77
1.79
1.6
1.4
—
—
—
0
0
65
475
1.39
1.74
1.7
2.1
4606.93
3880.33
u/l
0.10
21
192
868
8388
1.26
1.72
5.3
4.5
2.76
2.83
mmol/l
1.61
817
7826
41
277
1.50
1.66
1.2
1.2
—
—
—
0
0
15
76
1.99
1.65
2.5
3.1
—
—
—
0
0
18
98
1.85
1.62
1.7
1.4
—
32.83
—
0
6
10
43
2.34
1.59
1.1
1.3
—
—
—
0
0
23
137
1.69
1.56
2.2
1.4
—
—
—
0
0
29
187
1.57
1.47
1.4
1.6
589.67
724.44
e6/l
0.06
24
154
15
80
1.89
1.45
1.3
1.1
—
—
—
0
0
25
156
1.62
1.44
3.1
7.4
11.44
11.11
mmol/l
0.19
25
142
25
156
1.62
1.44
3.1
7.4
103.16
105.41
mmol/l
1.33
25
142
16
88
1.83
1.42
4.6
5.0
10.42
53.89
u/ml
—
6
26
27
173
1.58
1.41
2.8
2.2
61.21
103.91
ug/min
0.43
17
109
196
1696
1.19
1.41
5.4
4.8
2.68
2.27
ug/l
0.58
185
1515
46
331
1.41
1.39
1.3
1.2
—
—
—
0
0
6
23
2.62
1.37
1.0
1.1
—
—
—
0
0
13
68
1.92
1.33
1.9
2.5
—
—
—
0
0
37
258
1.45
1.33
1.2
1.3
10.65
10.52
u/l
0.02
24
209
36
250
1.46
1.32
1.2
1.2
—
—
—
0
0
6
24
2.51
1.30
1.0
1.0
—
—
—
0
0
5
18
2.79
1.28
1.6
1.4
—
—
—
0
0
28
187
1.51
1.25
1.5
1.6
39.35
9.33
e6/l
0.45
23
149
40
289
1.40
1.21
1.3
1.5
—
—
—
0
0
60
464
1.31
1.19
3.3
3.1
5.07
5.14
kpa
0.33
54
447
27
182
1.50
1.16
1.4
1.4
27.12
26.12
u/l
0.05
20
152
5
20
2.51
1.15
1.0
1.5
10.38
14.08
g/l
—
5
15
23
150
1.55
1.15
1.3
1.1
—
11.65
—
0
13
33
234
1.42
1.12
1.1
1.1
—
—
—
0
0
11
59
1.87
1.07
1.0
1.2
—
—
—
0
0
13
74
1.77
1.07
3.0
2.8
3.13
1.68
g/24h
—
6
39
7
33
2.13
1.05
1.0
1.0
—
—
—
0
0
16
98
1.64
1.03
1.6
1.3
—
—
—
0
0
5
22
2.28
1.03
1.0
1.1
—
—
—
0
0
5
22
2.28
1.03
1.0
1.1
—
—
—
0
0
5
22
2.28
1.03
1.0
1.1
—
—
—
0
0
19
122
1.57
1.03
1.9
1.4
—
—
—
0
0
41
309
1.34
1.00
3.0
2.6
0.63
0.66
%
0.25
41
309
34
250
1.37
0.97
1.9
1.9
—
—
—
0
0
14
85
1.66
0.94
1.8
1.7
—
—
—
0
0
6
27
2.23
0.93
3.0
2.0
59.23
51.83
ug/l
—
6
27
47
367
1.29
0.91
1.3
1.5
—
—
—
0
0
240
2184
1.13
0.90
4.7
3.7
0.00
0.01
estimate
1.08
70
771
23
160
1.45
0.89
1.0
1.1
1.40
2.48
u/ml
0.78
11
77
6
29
2.08
0.89
1.7
1.7
—
—
—
0
0
13
79
1.65
0.88
1.1
1.1
—
—
—
0
0
6
31
1.94
0.84
2.2
1.7
—
—
—
0
0
46
365
1.27
0.81
1.3
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
39.00
—
0
15
6
33
1.82
0.79
1.5
1.7
—
—
—
0
0
11
66
1.67
0.79
1.1
1.4
1.67
1.57
nmol/l
0.09
11
59
16
107
1.50
0.76
1.4
1.3
—
—
—
0
0
253
2333
1.11
0.76
4.0
3.0
—
—
—
0
0
43
342
1.27
0.75
1.3
1.5
—
—
—
0
0
46
369
1.26
0.75
1.3
1.5
—
—
—
0
0
12
185
0.64
0.75
3.4
2.7
7.40
7.42
ph
0.58
12
163
11
67
1.65
0.75
1.3
1.1
—
—
—
0
0
45
362
1.25
0.73
1.3
1.5
—
—
—
0
0
23
169
1.37
0.70
1.4
1.6
—
—
—
0
0
17
118
1.45
0.69
2.8
2.6
—
—
—
0
0
72
619
1.18
0.63
4.1
4.2
0.05
0.11
%
0.64
22
182
19
138
1.38
0.62
1.8
1.7
—
—
—
0
0
15
104
1.45
0.62
1.5
1.6
—
—
—
0
0
14
199
0.70
0.62
1.4
2.1
—
—
—
0
0
10
63
1.59
0.62
1.1
1.0
—
—
—
0
0
31
244
1.28
0.61
1.6
1.9
2.14
5.03
iu/l
—
9
89
80
697
1.16
0.60
1.3
1.2
143.51
151.82
iu/ml
0.05
26
290
11
162
0.68
0.59
3.4
3.9
56.45
56.56
%
0.01
11
162
44
364
1.22
0.58
1.2
1.3
236.48
241.23
miu/ml
0.04
22
177
49
410
1.21
0.58
1.3
1.6
303.47
316.67
mu/l
0.10
43
373
13
89
1.47
0.58
1.4
1.1
—
—
—
0
0
8
54
1.49
0.57
1.3
2.1
10.90
10.92
%
—
8
54
12
81
1.49
0.57
1.5
1.6
—
—
—
0
0
117
1054
1.12
0.55
2.0
1.8
—
—
—
0
0
207
1923
1.10
0.55
1.9
1.9
—
—
—
0
0
70
609
1.16
0.55
5.5
3.3
1.23
1.23
mmol/l
0.24
63
527
6
38
1.58
0.54
1.8
1.3
95.83
168.83
mmol/24h
—
6
38
14
99
1.42
0.54
1.2
1.1
—
—
—
0
0
9
62
1.46
0.53
1.6
1.2
6.24
6.31
mmol/l
—
9
57
21
161
1.31
0.52
1.5
1.7
—
—
—
0
0
6
40
1.50
0.51
2.7
3.4
—
—
—
0
0
44
370
1.20
0.51
1.0
1.1
—
—
—
0
0
11
157
0.70
0.51
3.2
3.6
4.19
4.19
e9/l
0.00
11
157
90
1006
0.88
0.51
1.4
1.3
—
—
—
0
0
176
1633
1.09
0.49
1.6
1.7
423.84
30281612.71
pmol/l
1.81
149
1387
16
121
1.33
0.44
1.2
1.2
—
—
—
0
0
10
69
1.45
0.44
1.0
1.1
174.80
221.95
mg/l
—
10
57
23
184
1.26
0.43
1.3
1.4
0.26
0.33
nmol/l
0.57
15
147
20
157
1.28
0.43
1.5
1.7
—
—
—
0
0
8
57
1.41
0.42
1.0
2.0
48.62
38.40
%
—
8
57
8
58
1.38
0.41
1.3
1.1
—
—
—
0
0
5
33
1.52
0.41
1.4
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
305
3187
0.94
0.40
2.6
2.6
—
—
—
0
0
18
141
1.28
0.40
3.3
2.7
—
—
—
0
0
8
60
1.34
0.40
1.3
1.5
—
—
—
0
0
5
35
1.43
0.39
1.2
4.0
—
—
—
0
0
9
67
1.35
0.38
2.1
1.5
—
—
—
0
0
67
602
1.12
0.37
1.8
1.7
—
—
—
0
0
66
594
1.12
0.35
4.1
4.3
0.00
0.68
%
0.66
16
159
9
125
0.72
0.35
4.8
2.5
—
—
—
0
0
10
73
1.37
0.34
1.3
1.1
31.50
37.83
mg/l
—
10
57
6
46
1.31
0.33
2.5
1.2
—
—
—
0
0
10
74
1.35
0.32
1.7
1.3
—
—
—
0
0
67
608
1.11
0.32
4.0
4.0
0.35
0.67
%
1.05
23
191
16
128
1.25
0.32
1.1
1.1
—
73.86
—
0
28
47
527
0.89
0.31
2.1
2.5
—
—
—
0
0
11
84
1.31
0.30
4.7
2.2
—
—
—
0
0
72
660
1.10
0.29
4.1
4.1
0.82
1.06
%
0.20
22
224
9
72
1.25
0.25
3.7
2.9
—
—
—
0
0
12
147
0.81
0.23
4.3
2.6
—
—
—
0
0
16
134
1.20
0.23
1.2
1.6
—
—
—
0
0
5
39
1.28
0.23
1.2
3.6
—
—
—
0
0
10
79
1.27
0.22
1.6
2.0
31.90
32.29
pg
—
10
79
5
41
1.22
0.22
2.0
1.4
—
—
—
0
0
13
107
1.22
0.21
1.9
2.8
—
—
—
0
0
5
42
1.19
0.21
2.0
1.4
140.60
145.67
nmol/l
—
5
42
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
6.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
5.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
65
607
1.08
0.20
1.4
1.4
—
—
—
0
0
12
99
1.21
0.19
1.6
1.7
—
—
—
0
0
14
165
0.85
0.19
3.5
4.1
24.79
25.91
mg/l
—
9
102
17
147
1.16
0.18
1.6
1.2
—
—
—
0
0
7
59
1.19
0.18
3.4
3.0
—
—
—
0
0
7
62
1.13
0.17
1.0
1.2
—
—
—
0
0
7
63
1.11
0.17
13.6
12.0
0.61
0.65
mmol/l
—
7
58
11
92
1.20
0.16
1.0
1.1
—
—
—
0
0
10
83
1.21
0.15
1.2
1.1
—
—
—
0
0
20
178
1.13
0.15
7.3
4.2
—
—
—
0
0
5
47
1.06
0.09
1.4
1.2
184.20
487.63
u/l
—
5
41
15
136
1.10
0.08
1.1
1.4
—
—
—
0
0
24
257
0.93
0.08
5.0
8.9
—
—
—
0
0
7
64
1.09
0.08
1.3
1.3
67.00
74.23
umol/l
—
7
64
7
64
1.09
0.08
1.1
1.2
—
—
—
0
0
10
88
1.14
0.08
1.9
1.9
—
—
—
0
0
7
65
1.08
0.08
1.0
1.5
1.47
1.19
promille
—
7
51
20
187
1.07
0.06
1.0
1.1
—
—
—
0
0
13
122
1.07
0.02
1.2
1.5
—
—
—
0
0
15
158
0.95
0.02
3.2
2.3
128.00
130.11
g/l
—
8
120
24
233
1.03
0.01
1.4
1.3
—
—
—
0
0
27
277
0.97
0.01
1.4
1.4
—
—
—
0
0
12
114
1.05
0.00
1.8
1.4
44.86
66.58
mmol/l
—
7
96
36
354
1.02
0.00
1.8
1.7
—
—
—
0
0
28
284
0.99
0.00
1.5
1.5
—
—
—
0
0
36
356
1.01
0.00
5.2
3.0
—
—
—
0
0
17
168
1.01
0.00
1.1
1.1
—
—
—
0
0
17
168
1.01
0.00
1.1
1.1
—
—
—
0
0
19
187
1.02
0.00
1.5
1.6
7282.64
14087.89
e6/l
0.86
11
142
20
197
1.02
0.00
1.2
1.1
—
—
—
0
0
112
1123
1.00
0.00
1.6
1.6
—
—
—
0
0
27
275
0.98
0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
18.30
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
41.33
—
0
9
9
96
0.94
-0.00
2.7
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
60
1.00
-0.00
2.5
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
56
0.89
-0.00
2.2
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
8
85
0.94
-0.00
3.4
2.5
—
—
—
0
0
8
86
0.93
-0.00
3.4
2.5
4.40
3.99
mmol/l
—
8
86
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.5
—
—
—
0
0
8
86
0.93
-0.00
3.4
2.5
107.63
105.99
mmol/l
—
8
86
0
6
0.00
-0.00
0.0
1.5
—
2.58
—
0
6

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_LIVE_BILE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_LIVE_BILE 1.65 [1.41, 1.93] < 0.001
Birth year 0.994 [0.99, 1.0] 0.164

During the follow-up period (1.1.1998 — 31.12.2019), 315 out of 2402 females with CD2_BENIGN_LIVE_BILE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_LIVE_BILE 1.985 [1.62, 2.42] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1102 males with CD2_BENIGN_LIVE_BILE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_LIVE_BILE.

N-year risk Females Males
1 0.15% 0.324%
5 0.89% 2.124%
10 2.35% 5.521%
15 4.438% 10.241%
20 7.635% 16.824%

Relationships between endpoints

Index endpoint: CD2_BENIGN_LIVE_BILE – Benign neoplasm: Liver/bile ducts

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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