reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
353 |
4. Check minimum number of eventsNone |
353 |
5. Include endpointsNone |
353 |
6. Filter based on genotype QC (FinnGen only) |
348 |
Control definitions (FinnGen only)
- Control exclude
- RHEUMA_ARHTROPAT_REACTIVE
Extra metadata
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M02
- Name in latin
- Arthropathia post infectionem intestinalem
Similar endpoints
↥List of similar endpoints to
Postdysenteric arthropathy
based on the number of shared cases.
Similar with more cases:
- Reactive arthropathies, FINNGEN
- Reactive arthropathies
- Finngen Rheumatological endpoints
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2221 | 1079 | 1138 |
| Only index persons | 2145 | 1048 | 1097 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 45.19 | 45.69 | 44.72 |
| Only index persons | 44.97 | 45.57 | 44.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 348 | 186 | 162 |
| Unadjusted period prevalence (%) | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | 47.06 | 46.45 | 47.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 353
- Matched controls
- 3530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M02.1
ICD-10 Finland
Postdysenteric arthropathy
+∞
307.7
352
*
A07EC01
ATC
sulfasalazine; oral, rectal
22.5
184.2
168
137
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
1672.3
124.9
114
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
12.9
123.8
158
208
M13.9
ICD-10 Finland
Arthritis, unspecified
13.4
106.1
120
131
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
12.1
88.5
104
118
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
12.5
88.5
101
110
L04AX03
ATC
methotrexate; systemic
8.1
66.9
110
186
H02AB06
ATC
prednisolone; systemic
5.8
52.0
259
1139
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
14.4
51.4
49
39
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
14.5
49.6
47
37
M02.8
ICD-10 Finland
Other reactive arthropathies
250.4
44.0
44
*
L01BA01
ATC
methotrexate; systemic
11.8
40.1
43
41
L88
ICPC
Rheumatoid/seropositive arthritis
9.9
35.3
43
49
J01MA02
ATC
ciprofloxacin; systemic
3.6
31.6
191
866
M45
ICD-10 Finland
Ankylosing spondylitis
10.4
31.1
36
38
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
7.6
29.6
45
67
P01BA02
ATC
hydroxychloroquine; oral
5.1
27.2
64
146
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.2
20.6
104
404
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
19.7
16.2
24
13
L04AB04
ATC
adalimumab; parenteral
12.6
15.3
27
23
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
7.0
14.7
23
35
H02AB07
ATC
prednisone; oral
3.1
14.2
67
246
A02BC02
ATC
pantoprazole; systemic
2.5
13.7
257
1812
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
13.5
126
654
M25.5
ICD-10 Finland
Pain in joint
2.4
13.3
144
798
S01BA01
ATC
dexamethasone; ophthalmic
5.8
13.3
25
46
L04AB06
ATC
golimumab; parenteral
29.6
13.1
17
6
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.3
12.7
22
37
L04AB01
ATC
etanercept; parenteral
18.2
12.7
19
11
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
16.6
12.3
19
12
M01AH01
ATC
celecoxib; oral
2.7
11.5
73
313
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
10.6
11.2
21
21
A02.0
ICD-10 Finland
Salmonella enteritis
29.0
10.8
14
5
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
10.6
153
934
N02AX02
ATC
tramadol; systemic, rectal
2.1
10.2
168
1073
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
4.6
10.0
24
55
M01AH05
ATC
etoricoxib; oral
2.1
9.6
239
1760
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.9
9.5
29
80
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
12.8
9.4
16
13
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
8.9
48
188
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
11.1
8.9
16
15
M02.3
ICD-10 Finland
Reiter disease
+∞
8.4
8
*
M01AE02
ATC
naproxen; oral, rectal
2.0
8.3
220
1619
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
22.6
8.1
11
5
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
13.4
7.9
13
10
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.6
7.8
19
30
S01BA04
ATC
prednisolone; ophthalmic
7.0
7.7
18
27
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
7.6
160
1082
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
7.4
7.6
17
24
A02BC05
ATC
esomeprazole; systemic
1.9
7.5
151
1006
TNG10
NOMESCO Finland
Puncture of knee
8.6
7.4
15
18
A04.5
ICD-10 Finland
Campylobacter enteritis
11.2
7.4
13
12
M02
ICD-10 Finland
Reactive arthropathies
+∞
7.3
7
*
M03.2*A04.6
ICD-10 Finland
Postinfectious arthropathy in enteritis due to Yersinia enterocolitica
+∞
7.3
7
*
4AB02, ,
NOMESCO Finland
30.7
7.2
9
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
7.2
102
604
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.0
7.2
32
113
R50.9
ICD-10 Finland
Fever, unspecified
2.3
7.1
61
298
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.6
6.9
41
169
M03BX02
ATC
tizanidine; oral
1.8
6.9
230
1775
L04AA01
ATC
[U] ciclosporin
17.1
6.8
10
6
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.5
6.7
43
184
L04AA13
ATC
[U] leflunomide
5.7
6.7
18
33
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
27.2
6.3
8
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
74
67
13.71
72.56
1.6
1.4
—
—
—
0
0
60
59
12.05
55.28
1.8
1.5
17165.40
19485.70
e6/l
0.09
42
43
35
25
15.43
38.74
1.7
1.4
62.16
68.21
%
0.32
25
19
238
1382
3.22
23.77
9.0
6.1
30.29
28.28
%
1.88
230
1313
234
1371
3.10
22.51
8.5
5.9
54.83
56.82
%
1.65
227
1304
260
1656
3.16
20.79
10.9
9.4
3.79
4.08
e9/l
1.67
241
1456
30
17
19.15
19.93
1.7
1.5
29.77
30.00
%
0.01
24
12
114
483
3.01
19.31
1.3
1.2
3.96
9.61
u/ml
0.96
46
200
299
2135
3.62
18.31
7.9
3.8
12.34
10.79
mm/h
1.09
289
1973
34
65
5.68
17.39
1.7
1.5
—
—
—
0
0
112
499
2.82
17.02
1.3
1.3
17.33
31.62
iu/ml
1.76
47
175
134
732
2.34
12.69
2.6
2.7
315.91
6997.52
umol/l
3.07
123
652
21
24
9.23
10.43
1.4
1.1
7733.00
534621.94
e6/l
0.78
16
18
52
203
2.83
9.76
2.4
2.3
35.92
18.30
au/ml
—
6
13
202
1399
2.04
9.65
5.4
4.6
0.00
0.00
estimate
0.50
54
261
202
1399
2.04
9.65
4.4
3.3
0.00
0.00
estimate
0.50
54
273
203
1419
2.01
9.33
4.5
3.4
0.00
0.00
estimate
-0.00
46
243
23
55
4.40
9.06
3.7
3.6
4.06
4.44
e9/l
0.36
23
55
23
55
4.40
9.06
4.1
4.1
55.91
56.93
%
0.16
23
55
273
2187
2.10
7.82
10.2
7.5
76.34
78.42
u/l
0.39
267
2061
27
90
3.17
6.65
1.9
1.5
0.27
0.05
iu/ml
—
7
17
162
1137
1.79
6.55
2.4
2.3
75.72
75.69
nmol/l
0.00
153
1030
329
2926
2.83
6.11
20.8
12.6
25.44
22.60
mg/l
0.68
303
2265
39
173
2.41
5.64
1.6
1.6
—
—
—
0
0
23
82
2.93
5.08
1.3
1.2
—
—
—
0
0
23
83
2.89
4.98
1.3
1.2
—
—
—
0
0
312
2776
2.07
4.68
16.1
11.5
87.92
86.19
ml/min/173m2
0.78
291
2268
96
628
1.73
4.68
2.1
1.9
2.84
2.99
mg/l
0.34
83
531
35
161
2.30
4.68
1.7
1.3
—
—
—
0
0
108
732
1.68
4.61
5.5
3.4
0.00
0.02
estimate
0.69
51
251
149
1106
1.60
4.40
4.7
3.4
—
—
—
0
0
100
675
1.67
4.30
1.4
1.3
0.86
1.55
u/ml
0.59
28
196
339
3141
3.00
4.29
15.5
9.9
26.66
27.65
u/l
0.56
334
3046
67
409
1.79
4.11
1.7
2.2
—
—
—
0
0
63
380
1.80
4.02
1.7
2.0
—
—
—
0
0
18
64
2.91
4.02
1.2
1.5
—
—
—
0
0
254
2172
1.60
3.84
4.1
3.9
14.81
14.64
pmol/l
0.44
244
1988
87
582
1.66
3.83
1.5
1.5
19.99
20.77
nmol/l
0.23
81
500
106
748
1.60
3.76
3.1
2.7
0.24
0.44
e6/l
0.90
88
552
87
585
1.65
3.75
1.4
1.5
—
—
—
0
0
159
1238
1.52
3.60
3.0
2.7
131.97
121.01
ug/l
0.30
153
1149
13
36
3.71
3.53
1.2
1.6
—
—
—
0
0
13
36
3.71
3.53
1.2
1.6
—
—
—
0
0
13
36
3.71
3.53
1.2
1.6
—
—
—
0
0
12
31
3.97
3.52
1.3
1.2
—
—
—
0
0
72
471
1.66
3.44
3.5
2.8
2.42
2.45
mmol/l
0.77
63
415
129
973
1.51
3.34
3.4
2.9
—
—
—
0
0
145
1125
1.49
3.26
4.5
5.1
36.16
36.19
g/l
0.02
130
1062
119
891
1.51
3.16
2.9
3.4
2.34
2.35
mmol/l
0.45
109
794
89
626
1.56
3.15
1.6
1.7
0.73
1.20
mg/l
2.69
68
470
12
35
3.51
3.13
1.2
1.6
—
—
—
0
0
12
36
3.41
3.05
1.2
1.6
—
—
—
0
0
12
36
3.41
3.05
1.2
1.6
—
—
—
0
0
67
445
1.62
3.00
2.7
3.3
0.83
0.82
mmol/l
0.29
62
424
7
13
5.47
2.88
1.1
1.3
5.59
1.72
mmol/l
—
7
13
19
85
2.31
2.75
2.3
1.4
—
—
—
0
0
15
60
2.57
2.74
1.0
1.2
—
—
—
0
0
148
1190
1.42
2.62
14.5
11.4
1.16
1.18
inr
0.13
59
362
292
2661
1.56
2.59
4.9
4.5
1.80
2.30
mu/l
0.57
280
2453
8
20
4.07
2.58
1.1
1.1
282.38
169.18
iu/ml
—
8
20
192
1621
1.40
2.55
4.0
5.0
6.51
6.66
mmol/l
0.47
183
1517
6
12
5.07
2.41
1.3
1.8
—
—
—
0
0
344
3314
2.49
2.40
26.7
18.7
40.81
40.82
%
0.02
334
3140
64
445
1.54
2.36
2.4
2.5
0.52
0.74
e6/l
0.57
37
238
9
28
3.27
2.32
1.4
1.7
—
—
—
0
0
12
47
2.61
2.29
1.0
1.1
—
—
—
0
0
6
13
4.67
2.28
1.3
1.8
—
—
—
0
0
7
18
3.94
2.26
1.4
1.6
—
—
—
0
0
10
36
2.83
2.15
1.4
1.6
—
—
—
0
0
41
268
1.60
1.98
2.4
2.4
71.66
35.79
u/l
0.50
35
226
172
1466
1.34
1.97
5.8
6.5
10.07
10.91
umol/l
1.21
165
1393
5
11
4.59
1.94
6.2
3.2
37700.00
37209.09
ug/l
—
5
11
124
1008
1.35
1.94
3.8
3.3
92.17
39.19
ng/l
0.32
71
645
6
16
3.80
1.94
1.3
1.7
—
—
—
0
0
13
58
2.29
1.93
1.2
1.1
0.17
2.86
u/ml
—
5
30
233
2081
1.35
1.93
3.7
3.2
—
—
—
0
0
16
79
2.07
1.88
1.1
1.3
—
—
—
0
0
59
424
1.47
1.87
2.6
2.6
1.82
2.03
e6/l
0.09
31
218
315
2975
1.55
1.77
16.7
14.4
3.94
3.96
mmol/l
0.82
309
2900
314
2964
1.54
1.77
16.6
14.3
139.45
139.67
mmol/l
0.86
308
2894
5
13
3.88
1.72
1.8
1.2
11.20
13.31
u/l
—
5
13
48
337
1.49
1.71
2.4
2.7
4.54
8.63
umol/l
2.45
43
285
125
1036
1.32
1.68
2.1
1.8
100.13
97.36
pmol/l
0.28
77
545
5
14
3.61
1.62
1.0
1.2
—
—
—
0
0
5
14
3.61
1.62
1.0
1.1
—
—
—
0
0
5
14
3.61
1.62
1.0
1.0
—
—
—
0
0
16
86
1.90
1.53
1.2
1.7
—
—
—
0
0
25
155
1.66
1.51
1.1
1.0
—
—
—
0
0
14
72
1.98
1.51
1.5
1.4
230.25
295.73
ug/g
—
8
40
15
80
1.91
1.47
1.0
1.1
—
—
—
0
0
99
808
1.31
1.47
2.5
2.0
129.43
203.56
u/l
1.97
90
770
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
16
3.15
1.44
1.0
1.1
—
—
—
0
0
18
103
1.79
1.43
1.6
1.7
—
304.00
—
0
5
26
166
1.61
1.42
1.6
2.0
—
—
—
0
0
38
267
1.47
1.37
2.2
2.1
334.82
384.41
nmol/l
0.92
38
246
149
1296
1.26
1.32
5.8
7.2
1.22
1.21
mmol/l
0.59
127
1120
16
92
1.77
1.27
1.1
1.2
—
—
—
0
0
63
492
1.34
1.26
1.5
1.7
488.70
17590799.98
pmol/l
0.50
57
415
10
49
2.07
1.23
1.4
1.9
—
—
—
0
0
30
206
1.50
1.22
1.7
2.1
—
—
—
0
0
11
57
1.96
1.18
1.2
1.6
—
—
—
0
0
6
130
0.45
1.18
2.3
4.1
26.22
25.19
mmol/l
—
6
130
8
40
2.02
1.12
1.5
1.7
—
—
—
0
0
105
892
1.25
1.12
3.2
2.7
57.37
62.91
u/l
0.40
99
825
10
53
1.91
1.02
1.2
1.1
—
—
—
0
0
39
295
1.36
0.98
1.6
1.8
—
—
—
0
0
7
36
1.96
0.97
1.0
1.2
—
—
—
0
0
0
32
0.00
0.95
0.0
1.2
—
—
—
0
0
281
2672
1.25
0.94
5.4
5.4
38.41
39.48
mmol/mol
1.41
268
2513
7
127
0.54
0.90
1.4
2.7
0.49
0.69
%
—
7
127
6
29
2.09
0.89
1.2
1.3
—
—
—
0
0
15
96
1.59
0.85
1.0
1.4
286.43
313.17
miu/ml
—
6
51
6
31
1.95
0.84
1.5
1.3
18.91
3.02
ug/l
—
6
26
28
207
1.38
0.82
1.6
2.8
84.45
70.07
ml/min/173m2
1.65
11
88
53
431
1.27
0.82
1.7
1.6
1379.06
1185.57
nmol/l
0.70
44
337
51
413
1.27
0.82
2.0
1.9
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
38
298
1.31
0.78
1.7
1.9
—
—
—
0
0
6
34
1.78
0.76
1.0
1.4
149.55
183.94
pmol/l
—
6
34
5
25
2.01
0.73
1.4
1.5
59.80
71.92
umol/l
—
5
25
11
68
1.64
0.72
4.0
3.0
—
3.63
—
0
6
7
40
1.76
0.71
1.4
1.8
—
—
—
0
0
76
655
1.20
0.71
2.8
2.3
—
—
—
0
0
93
817
1.19
0.70
3.2
3.9
24.68
10.27
mg/mmol
0.72
61
529
9
59
1.54
0.69
1.2
1.4
—
—
—
0
0
7
42
1.68
0.68
1.0
1.1
—
—
—
0
0
7
43
1.64
0.67
1.3
1.3
—
—
—
0
0
7
43
1.64
0.67
1.3
1.3
—
—
—
0
0
63
538
1.21
0.65
3.0
2.6
0.64
0.74
ug/l
0.62
38
329
11
71
1.57
0.63
1.5
1.8
—
—
—
0
0
33
263
1.28
0.62
4.8
2.9
—
—
—
0
0
13
89
1.48
0.59
3.1
1.8
—
—
—
0
0
10
149
0.66
0.58
1.4
1.4
—
—
—
0
0
8
54
1.49
0.57
1.5
1.7
—
—
—
0
0
23
295
0.76
0.57
5.3
10.5
-0.00
1.00
mmol/l
0.92
16
244
8
123
0.64
0.55
3.4
3.9
42.99
50.17
%
—
8
123
31
250
1.26
0.54
3.7
4.3
79.81
24.44
ug/l
0.31
21
208
14
101
1.40
0.50
3.1
1.4
1.30
1.17
g/l
0.69
14
96
58
505
1.18
0.50
3.7
3.4
81.15
260.26
ng/l
1.29
39
361
7
46
1.53
0.48
1.4
1.3
—
—
—
0
0
141
1312
1.12
0.48
2.5
2.6
—
—
—
0
0
7
47
1.50
0.48
1.4
1.7
—
—
—
0
0
8
116
0.68
0.46
1.3
1.4
271.50
305.63
mu/l
—
8
106
11
152
0.71
0.45
4.0
2.4
39.55
56.02
u/ml
0.32
11
144
73
655
1.14
0.44
3.2
3.1
1962.67
1024.31
ng/l
0.54
62
537
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
13
96
1.37
0.42
3.5
2.0
0.49
3.98
ug/l
0.66
13
88
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
0.97
—
0
10
10
72
1.40
0.37
1.5
1.8
—
—
—
0
0
304
2979
1.15
0.36
4.7
4.7
2.85
2.83
mmol/l
0.20
290
2786
14
108
1.31
0.36
1.4
2.2
—
—
—
0
0
6
42
1.44
0.35
1.0
1.1
—
—
—
0
0
300
2944
1.13
0.31
4.3
4.3
4.76
4.72
mmol/l
0.34
286
2767
84
778
1.10
0.31
1.8
1.7
1.30
1.45
mmol/l
1.04
74
666
12
93
1.30
0.30
3.3
2.0
—
—
—
0
0
7
56
1.25
0.29
1.6
1.4
—
—
—
0
0
24
206
1.18
0.27
1.3
1.2
98.50
126.02
iu/ml
—
10
80
5
74
0.67
0.26
1.6
1.5
—
—
—
0
0
5
74
0.67
0.26
1.6
1.5
—
—
—
0
0
298
2931
1.11
0.26
4.2
4.2
1.48
1.45
mmol/l
0.59
285
2738
78
730
1.09
0.24
3.7
3.8
20.90
21.92
%
0.28
36
314
214
2081
1.07
0.24
3.4
3.3
49.51
48.57
u/l
0.07
202
1966
21
241
0.86
0.22
2.2
4.0
1.35
1.92
mmol/l
0.26
15
197
10
124
0.80
0.22
1.4
1.7
—
—
—
0
0
6
48
1.25
0.20
2.5
4.1
—
3856.00
—
0
7
6
48
1.25
0.20
1.3
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
96
913
1.07
0.20
4.4
4.3
1.66
1.98
ug/l
0.76
87
823
35
320
1.10
0.18
6.4
7.4
105.26
103.91
mmol/l
1.24
35
320
7
62
1.13
0.17
1.0
1.4
—
108.85
—
0
13
5
67
0.74
0.17
1.0
1.2
—
—
—
0
0
8
70
1.15
0.16
1.4
1.4
—
—
—
0
0
8
71
1.13
0.16
1.0
1.2
—
—
—
0
0
9
78
1.16
0.15
1.4
2.9
—
—
—
0
0
31
337
0.91
0.15
4.2
4.3
31.38
31.42
%
0.01
21
233
16
141
1.14
0.14
1.6
1.6
—
—
—
0
0
12
103
1.17
0.14
1.2
1.4
—
—
—
0
0
46
488
0.93
0.13
1.3
1.4
—
—
—
0
0
285
2820
1.06
0.12
4.5
4.3
5.83
5.91
mmol/l
0.66
274
2610
34
318
1.08
0.11
7.2
6.8
—
—
—
0
0
281
2836
0.96
0.10
3.9
3.8
1.31
1.32
mmol/l
0.10
267
2632
7
66
1.06
0.08
1.0
1.2
—
53.30
—
0
5
6
74
0.81
0.07
1.2
1.3
—
—
—
0
0
7
80
0.87
0.07
1.6
1.6
—
—
—
0
0
9
87
1.04
0.07
1.7
1.4
—
—
—
0
0
13
142
0.91
0.06
1.6
1.5
—
—
—
0
0
30
311
0.96
0.04
1.4
1.8
—
—
—
0
0
6
67
0.89
0.00
1.8
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
68.64
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
49
1.02
-0.00
1.6
3.0
16.00
33.56
u/ml
—
5
49
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
-0.00
1.5
2.0
221.75
184.61
%
—
8
84
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.4
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint ARTRHO_POSTDYSENTERIC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ARTRHO_POSTDYSENTERIC | 1.182 [0.9, 1.55] | 0.228 |
| Birth year | 0.999 [0.99, 1.01] | 0.765 |
During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 974 females with ARTRHO_POSTDYSENTERIC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ARTRHO_POSTDYSENTERIC | 0.814 [0.65, 1.02] | 0.071 |
| Birth year | 0.986 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 1010 males with ARTRHO_POSTDYSENTERIC died.
Mortality risk
Mortality risk for people of age
years, who have ARTRHO_POSTDYSENTERIC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.104% | 0.138% |
| 5 | 0.787% | 0.85% |
| 10 | 1.998% | 2.199% |
| 15 | 3.78% | 4.239% |
| 20 | 6.482% | 7.309% |
Relationships between endpoints
↥Index endpoint: ARTRHO_POSTDYSENTERIC – Postdysenteric arthropathy
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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