Chylothorax

J10_CHYLOTHORAX

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J94.0
  • Cause of death: ICD-10 J94.0

2 out of 7 registries used, show all original rules.

79

4. Check minimum number of events

None

79

5. Include endpoints

None

79

6. Filter based on genotype QC (FinnGen only)

75

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 75 30 45
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 64.77 58.32 69.07

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
79
Matched controls
790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J94.0
ICD-10 Finland
Chylous effusion
+∞
113.6
79
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
51.1
21.4
25
7
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
30.1
21.0
28
14
J94.8
ICD-10 Finland
Other specified pleural conditions
56.3
20.9
24
6
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
45.4
19.3
23
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.7
12.9
35
97
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
139.5
11.8
12
*
C03CA01
ATC
furosemide; systemic
5.0
11.5
47
179
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.4
9.9
19
37
J94.9
ICD-10 Finland
Pleural condition, unspecified
113.0
9.6
10
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
9.4
8.8
18
24
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
100.3
8.6
9
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
8.3
55
280
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
12.8
8.2
14
13
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
+∞
7.4
7
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.7
7.2
18
33
JN4AD
NOMESCO Finland
Body CT examination
4.7
7.0
19
50
TGA30
NOMESCO Finland
Thoracocentesis
44.0
6.9
8
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
11.5
6.8
12
12
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.5
6.7
19
52
R06.0
ICD-10 Finland
Dyspnoea
3.5
6.6
35
148
R4190
NOMESCO Finland
Nutritional therapy
6.4
6.3
16
30
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.3
6.1
33
141

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
13
0
+∞
13.95
1.5
0.0
1.75
—
mmol/l
—
13
0
16
5
39.42
13.16
1.9
1.4
—
—
—
0
0
17
8
26.55
12.66
2.2
1.9
—
—
—
0
0
39
121
5.39
12.52
3.0
1.9
—
—
—
0
0
24
50
6.46
11.88
4.4
2.2
419.79
193.16
ng/l
0.79
24
43
49
196
4.95
11.22
7.1
4.3
—
—
—
0
0
38
126
4.88
11.02
10.5
5.5
0.80
0.81
mmol/l
0.47
38
117
64
321
6.23
10.89
20.6
14.3
1.40
1.33
inr
0.17
20
87
24
74
4.22
7.28
11.0
8.5
1.98
1.12
mmol/l
0.38
19
59
25
80
4.11
7.21
4.0
6.9
5.90
8.76
umol/l
0.86
20
70
27
93
3.89
7.01
10.3
9.3
104.07
104.28
mmol/l
0.10
27
93
11
12
10.43
6.01
2.7
1.7
—
—
—
0
0
16
42
4.52
5.88
9.4
3.8
—
—
—
0
0
64
411
3.93
5.83
10.5
5.6
7.03
6.67
mmol/l
0.41
64
387
58
351
3.45
5.81
16.6
8.1
1.19
1.21
mmol/l
1.55
49
307
55
325
3.28
5.68
12.0
7.4
—
—
—
0
0
24
87
3.53
5.67
3.9
8.8
6.21
5.54
kpa
1.64
24
82
24
87
3.53
5.67
3.9
8.9
—
—
—
0
0
43
225
3.00
5.45
5.3
2.8
—
—
—
0
0
18
56
3.87
5.28
5.2
5.2
0.60
0.96
%
—
10
27
22
81
3.38
5.03
12.0
11.8
—
—
—
0
0
17
53
3.81
4.96
5.1
5.3
0.13
0.13
%
—
8
24
8
9
9.72
4.39
1.6
6.6
—
—
—
0
0
8
9
9.72
4.39
1.9
2.9
26.12
38.62
%
—
8
9
36
188
2.68
4.35
7.6
4.1
7.39
7.40
ph
—
10
37
22
88
3.08
4.35
1.6
1.5
—
—
—
0
0
16
53
3.53
4.25
4.9
5.1
0.33
0.69
%
—
9
24
42
242
2.57
4.10
4.3
4.5
76.65
41.09
e6/l
0.33
36
182
15
51
3.40
3.82
4.7
5.4
0.00
0.36
%
—
5
22
8
12
7.27
3.77
2.0
1.4
—
—
—
0
0
29
145
2.58
3.73
3.5
2.8
1.29
1.07
mg/l
0.27
23
113
53
352
2.54
3.68
11.2
6.7
0.04
0.04
e9/l
0.32
47
297
53
358
2.46
3.46
11.6
6.7
1.39
2.01
e9/l
2.89
47
314
30
158
2.45
3.42
2.3
1.9
1.31
1.29
mmol/l
0.04
25
130
53
359
2.45
3.42
12.6
7.2
0.18
0.20
e9/l
0.26
47
310
17
67
2.96
3.40
2.3
2.4
3.82
6.16
ug/l
1.20
17
59
52
351
2.41
3.36
11.4
6.8
0.71
0.59
e9/l
1.83
47
297
13
41
3.59
3.25
3.3
4.4
—
—
—
0
0
6
8
8.00
3.11
2.3
3.6
13.81
17.16
ug/l
—
6
8
16
64
2.88
3.11
24.2
13.7
26.31
24.73
mmol/l
0.59
16
64
11
32
3.82
3.04
15.0
9.9
—
—
—
0
0
57
411
2.39
3.02
5.4
4.1
—
—
—
0
0
5
5
10.55
3.02
1.2
1.2
—
—
—
0
0
12
38
3.54
3.01
1.8
3.2
0.09
0.03
e6/l
0.77
12
38
20
93
2.54
2.92
1.9
1.6
—
—
—
0
0
7
14
5.37
2.79
1.4
2.1
—
—
—
0
0
5
6
8.78
2.79
2.8
2.2
0.68
0.85
nmol/l
—
5
6
5
6
8.78
2.79
1.2
1.2
6.26
5.22
mg/l
—
5
6
6
10
6.38
2.75
16.5
2.5
—
—
—
0
0
12
42
3.18
2.69
2.1
6.7
0.52
0.63
%
0.68
12
42
12
44
3.04
2.68
2.1
6.5
1.28
1.25
%
0.04
12
44
17
76
2.58
2.67
2.6
8.3
4.29
4.79
kpa
0.56
17
71
32
192
2.12
2.57
3.2
3.8
—
—
—
0
0
10
32
3.43
2.54
12.4
5.3
—
—
—
0
0
22
114
2.29
2.52
3.8
3.2
2.47
2.47
mmol/l
0.00
22
100
6
12
5.31
2.45
1.8
1.3
—
—
—
0
0
21
108
2.29
2.44
1.3
2.0
—
—
—
0
0
6
14
4.54
2.19
1.7
1.7
125.17
132.00
g/l
—
6
7
13
57
2.53
2.11
18.9
6.8
—
—
—
0
0
22
124
2.07
2.03
2.5
2.3
2.20
2.34
g/l
0.42
22
111
7
21
3.55
2.01
1.0
1.7
—
—
—
0
0
27
165
1.97
2.00
1.4
1.4
—
—
—
0
0
9
34
2.85
1.93
1.2
1.3
—
—
—
0
0
31
203
1.87
1.85
19.8
7.4
—
—
—
0
0
55
433
1.89
1.80
4.3
4.4
—
—
—
0
0
12
56
2.35
1.71
1.4
1.4
—
—
—
0
0
6
19
3.33
1.69
1.2
1.3
—
—
—
0
0
14
71
2.18
1.66
1.2
1.6
—
—
—
0
0
30
202
1.78
1.60
3.8
3.5
6.66
7.67
mmol/l
0.61
25
167
11
51
2.34
1.59
2.6
2.4
—
—
—
0
0
6
21
3.00
1.53
1.5
1.9
—
—
—
0
0
5
16
3.26
1.46
1.6
2.0
—
—
—
0
0
43
328
1.68
1.44
3.4
4.0
0.00
0.00
estimate
—
8
53
26
173
1.75
1.43
2.7
4.2
0.00
0.00
estimate
—
8
49
42
323
1.64
1.33
4.8
5.6
0.00
0.00
estimate
—
10
54
15
86
1.92
1.30
1.5
1.5
—
—
—
0
0
27
186
1.69
1.30
4.2
3.2
47.75
96.75
mg/l
1.06
22
122
63
545
1.77
1.20
52.9
19.1
16.24
15.28
%
0.67
63
538
41
321
1.58
1.16
3.4
4.0
0.00
0.00
estimate
—
9
58
28
200
1.62
1.16
4.4
3.8
7.62
12.33
mg/mmol
0.49
20
124
25
176
1.62
1.09
3.1
3.7
—
—
—
0
0
55
465
1.60
1.09
4.7
4.0
15.05
14.71
pmol/l
0.32
50
415
14
85
1.79
1.02
1.3
1.3
—
—
—
0
0
64
565
1.70
1.02
4.9
4.7
1.96
1.96
mu/l
0.01
56
508
6
27
2.32
0.96
7.0
3.7
—
—
—
0
0
10
57
1.86
0.88
3.2
5.5
67.25
88.16
ng/l
—
10
48
71
659
1.76
0.82
34.9
14.1
—
—
—
0
0
27
206
1.47
0.81
4.6
4.3
—
—
—
0
0
14
93
1.61
0.76
1.6
1.6
—
—
—
0
0
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
12
83
1.53
0.55
1.3
1.3
—
—
—
0
0
5
31
1.65
0.44
1.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
56
518
1.28
0.39
59.7
21.5
327.21
333.06
g/l
4.42
56
518
5
78
0.62
0.38
1.0
1.4
—
—
—
0
0
6
42
1.46
0.36
1.0
2.0
—
—
—
0
0
24
204
1.25
0.34
2.6
3.3
—
—
—
0
0
62
585
1.28
0.33
4.4
4.8
6.10
6.07
mmol/l
0.06
55
532
16
190
0.80
0.27
2.6
2.9
—
—
—
0
0
57
600
0.82
0.27
5.2
5.3
2.34
2.65
mmol/l
1.75
49
546
30
268
1.19
0.26
2.3
2.0
86.23
94.73
pmol/l
0.68
18
136
28
249
1.19
0.25
2.1
2.3
—
—
—
0
0
0
10
0.00
0.21
0.0
14.9
—
11.12
—
0
10
56
584
0.86
0.19
4.4
4.7
1.23
1.44
mmol/l
2.95
50
526
26
281
0.89
0.14
3.9
5.4
1.58
3.16
ug/l
0.76
21
252
54
559
0.89
0.12
6.8
6.4
41.36
40.49
mmol/mol
0.22
47
515
17
155
1.12
0.10
3.4
4.0
—
—
—
0
0
6
58
1.04
0.08
1.5
1.3
—
—
—
0
0
8
75
1.07
0.08
5.1
4.6
—
—
—
0
0
15
161
0.92
0.05
2.9
3.0
0.62
0.69
ug/l
—
10
119
58
589
0.94
0.03
4.7
4.7
3.94
4.49
mmol/l
3.22
50
533
58
571
1.06
0.03
4.6
4.2
1.29
1.28
mmol/l
0.04
51
514
15
156
0.95
0.00
1.4
1.3
0.70
1.23
u/ml
—
6
38
0
5
0.00
-0.00
0.0
8.0
—
0.57
—
0
5
0
7
0.00
-0.00
0.0
2.4
—
1.14
—
0
7
7
78
0.89
-0.00
2.4
2.6
238.57
175.66
ug/g
—
7
64
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
60
1.00
-0.00
1.7
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.1
—
2.00
—
0
8
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
45.8
—
132.33
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
6.81
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
6
62
0.97
-0.00
1.8
3.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.20
—
0
8

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: J10_CHYLOTHORAX – Chylothorax

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).