Turner's syndrome

Q17_TURNE_SYNDR

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q96 Cause of death: ICD-10 — Q96 2 out of 7 registries used, show all original rules.	90
4. Check minimum number of events None	90
5. Include endpoints None	90
6. Filter based on genotype QC (FinnGen only)	90

Control definitions (FinnGen only)

Control exclude: Q17_CHROMOSOMAL_ABNORMALITI_NOT_ELSEW_CLASSIFIED

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Q9
Name in latin: Syndroma Turner

NAME	Q17_TURNE_SYNDR
CONTROL_EXCLUDE	Q17_CHROMOSOMAL_ABNORMALITI_NOT_ELSEW_CLASSIFIED
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q96
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q96
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Turner's syndrome based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1030	965	61
Only index persons	909	853	56
Unadjusted period prevalence (%)
Whole population	0.03	0.03	0.00
Only index persons	0.03	0.03	0.00
Median age at first event (years)
Whole population	15.85	16.16	9.17
Only index persons	17.47	18.00	9.51

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	90	84	6
Unadjusted period prevalence (%)	0.03	0.03	0.00
Median age at first event (years)	20.70	21.52	9.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3009214) Lutropin [Units/volume] in Serum or Plasma

7.34

12.98

2.7

1.7

6.6

11.9

u/l

0.77

(40765089) Chromosome analysis panel - Blood by G-banded

19.50

8.33

1.0

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

270

3.05

6.32

2.0

1.4

0.6

2.0

u/ml

1.27

(3007164) IgA [Mass/volume] in Serum or Plasma

243

2.83

5.53

2.0

1.3

2.0

g/l

0.07

134

(36660697) Celiac disease serology panel - Serum

111

3.05

5.07

1.4

1.2

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

297

2.43

4.11

3.4

2.3

66.2

72.1

nmol/l

1.04

273

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

10.48

3.01

7.0

4.2

2.9

2.2

ug/l

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

160

2.20

2.84

1.5

1.4

1.3

mmol/l

0.20

144

(3008898) HLA-B27 [Presence]

0.00

2.74

0.0

1.1

—

(3014007) Fractional oxyhemoglobin in Arterial blood

4.07

2.53

8.8

19.9

94.4

96.1

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

3.89

2.43

8.8

19.1

1.2

1.1

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

3.89

2.43

8.8

19.1

0.6

0.7

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

2.25

2.00

2.6

2.0

2.4

mmol/l

0.20

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

4.74

1.97

1.0

2.1

—

(3032080) INR in Blood by Coagulation assay

167

1.88

1.87

4.3

5.3

0.9

1.1

inr

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

4.00

1.74

1.2

1.0

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

2.02

1.65

1.7

2.5

1845.2

5212.0

u/l

—

(40761536) Microorganisms panel - Urine sediment

2.12

1.59

3.0

2.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

1.97

1.56

2.3

3.2

1463.3

577.9

ng/l

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

2.00

1.53

1.4

1.3

180.0

137.0

iu/ml

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.85

1.46

10.8

17.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

300

0.57

1.37

1.4

1.7

—

(3020682) Albumin/Creatinine [Ratio] in Urine

100

1.86

1.35

4.1

3.5

7.9

20.3

mg/mmol

0.60

(3019060) Gas panel - Arterial blood

2.72

1.23

2.2

4.6

—

(3044889) 12 lead EKG panel

382

1.55

1.22

3.0

2.6

—

(3023368) Bacteria identified in Blood by Culture

113

1.74

1.17

3.2

3.9

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.58

1.16

1.2

1.6

—

(3034770) Mitochondria Ab [Titer] in Serum

2.58

1.16

1.6

1.7

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

646

1.69

1.11

3.4

3.0

5.6

5.5

mmol/l

0.31

599

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

734

0.62

1.09

4.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

166

1.61

1.09

1.6

2.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.96

1.01

1.3

1.7

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.02

0.99

1.1

1.3

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

2.31

0.95

6.3

2.9

138.0

167.9

—

(4035726)

1.94

0.90

1.0

1.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.66

0.84

1.2

1.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

131

0.57

0.81

2.6

2.0

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.80

0.0

1.9

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.73

0.79

6.3

9.4

23.9

24.8

mmol/l

0.33

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.71

0.76

1.3

1.7

—

(40768443) Skin Pathology biopsy report

2.06

0.74

1.0

1.1

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.61

0.72

1.7

1.5

—

(3000494) Fungus identified in Specimen by Culture

1.68

0.72

1.3

—

(3015736) pH of Urine

317

0.71

2.1

2.9

—

(3021589) Normoblasts [#/volume] in Blood

361

1.37

0.71

6.7

8.1

0.0

e9/l

0.49

299

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.60

0.71

1.3

1.9

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

772

1.70

0.70

8.9

8.1

39.1

22.2

u/l

2.57

746

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

241

0.68

0.69

2.7

2.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

543

0.75

0.62

3.1

3.9

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

170

0.66

0.61

2.8

2.1

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.59

0.0

1.1

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

1.53

0.58

2.8

2.7

30.7

29.4

0.56

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.58

0.57

2.3

2.9

234.4

225.8

u/l

—

(3000991) Gas panel - Venous blood

1.58

0.57

9.8

12.1

—

(3019225) pH of Specimen

1.58

0.54

1.7

6.7

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.53

0.52

11.5

3.5

1.2

mmol/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

262

0.74

0.52

2.7

2.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.60

0.50

2.1

2.8

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

465

0.78

0.50

5.7

8.2

3.9

3.8

e9/l

0.11

406

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

174

0.70

0.49

1.5

1.7

—

(3009508) Creatinine [Moles/volume] in Urine

157

1.35

0.49

4.0

2.8

7.4

8.1

mmol/l

0.21

139

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.56

0.48

1.2

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.56

0.48

1.2

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.56

0.48

1.2

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.56

0.48

1.2

1.5

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

290

1.28

0.47

8.6

7.1

1.2

mmol/l

0.32

253

(3022217) INR in Platelet poor plasma by Coagulation assay

1.59

0.43

42.6

10.3

—

1.0

—

(3000492) Spirometry study

1.39

0.42

1.3

1.4

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.41

0.0

1.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.41

0.0

1.0

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

1.50

0.41

2.0

1.5

—

(3002256) Pathology report gross observation

1.43

0.40

1.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

756

1.37

0.37

12.9

11.3

38.0

39.5

1.00

654

(3011397) Hemoglobin [Presence] in Urine by Test strip

187

0.76

0.36

2.1

3.1

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.46

0.36

1.0

1.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

212

1.25

0.35

1.8

1.5

106.2

94.2

pmol/l

0.57

(40758558) Short blood count panel - Blood

196

0.78

0.34

5.8

7.1

—

(42870588) Differential panel, method unspecified - Blood

261

1.22

0.34

4.4

5.7

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

611

1.23

0.33

10.3

8.1

101.6

98.1

ml/min/173m2

0.69

478

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.71

0.33

1.3

1.6

—

(21494755) Public health laboratory ask at order entry panel

106

0.73

0.31

1.0

1.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

108

0.72

0.31

1.4

1.5

—

(3000850) Epithelial cells [#/volume] in Urine

150

0.77

0.30

1.9

2.3

6.8

7.2

e6/l

0.06

137

(3044640) Blood type and Crossmatch panel - Blood

227

1.20

0.28

1.9

2.2

—

(3005033) Fetal Nuchal fold Thickness US

0.69

0.27

1.2

1.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

0.69

0.27

1.4

1.5

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.69

0.27

1.2

1.4

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.69

0.27

4.8

1.7

—

(3042936) Bacteria identified in Isolate by Culture

0.68

0.27

1.0

2.1

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.67

0.27

1.2

1.5

—

(3036489) Thrombin time

1.37

0.24

3.0

2.4

24.6

20.9

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.76

0.24

2.1

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

192

1.19

0.23

1.9

3.9

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

1.23

0.22

1.2

1.9

1.3

2.6

mg/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

330

0.86

0.22

2.2

2.1

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

1.7

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.21

0.0

1.5

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.21

0.0

1.0

—

97.1

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.21

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

110

0.80

0.21

1.4

2.1

—

(3049717) Cytology report of Urine Cyto stain

0.00

0.21

0.0

1.7

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.21

0.0

2.7

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

120.5

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.21

0.0

1.8

—

13.3

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

253.5

—

(4306422)

0.00

0.20

0.0

1.0

—

(4094501)

0.00

0.20

0.0

1.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

157

1.18

0.19

1.8

2.7

20.1

18.1

ng/l

0.10

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

1.21

0.17

1.9

1.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

295

0.88

0.17

2.9

3.1

—

(1761868) Lipid panel - Serum or Plasma

256

1.14

0.17

2.7

2.1

—

(3012544) pH of Venous blood

1.12

0.16

3.3

6.1

—

(3000764) Benzodiazepines [Presence] in Urine

0.77

0.16

1.2

1.5

—

(3028300) Cannabinoids [Presence] in Urine

0.79

0.16

1.2

1.5

—

(3027944) Amphetamines [Presence] in Urine

0.79

0.16

1.2

1.5

—

(3027008) Opiates [Presence] in Urine

0.79

0.16

1.2

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

243

0.87

0.16

1.6

1.8

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

1.19

0.16

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

269

1.12

0.13

1.7

1.8

—

(40768804) Tissue Pathology biopsy report

279

1.11

0.13

1.9

—

(3013512) EKG study

123

1.16

0.13

3.1

2.9

—

(3030467) Casts [#/volume] in Urine by Automated count

191

1.13

0.13

2.0

2.8

0.1

0.2

e6/l

1.17

150

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

231

1.11

0.12

2.0

3.1

—

(3035350) Ketones [Presence] in Urine by Test strip

388

0.92

0.10

2.6

3.2

0.0

estimate

—

(3018095) Leukocytes [#/volume] in Urine

267

0.91

0.10

2.6

3.4

77.2

64.5

e6/l

0.09

179

(3022313) Gas panel - Capillary blood

1.09

0.10

3.8

11.0

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.04

0.09

1.4

1.2

—

(3026782) Osmolality of Urine

134

0.88

0.09

1.9

2.4

478.1

549.4

mosm/kgh2o

0.70

119

(3009261) Glucose [Presence] in Urine by Test strip

387

0.93

0.09

2.7

3.3

0.0

estimate

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

156

1.11

0.09

1.4

1.5

—

(3003694) ABO and Rh group [Type] in Blood

296

0.92

0.09

1.8

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

0.81

0.08

6.2

9.5

5.6

5.0

kpa

—

(3011288) Drugs identified in Urine by Screen method

0.82

0.08

1.8

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.03

0.08

1.3

1.5

—

(3016879) Cocaine [Presence] in Urine

0.83

0.08

1.2

1.5

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.11

0.08

1.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

224

0.92

0.07

3.1

2.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

234

0.92

0.07

1.7

1.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

385

0.93

0.07

3.6

4.6

0.0

estimate

—

(36304419) Bacteria [Presence] in Urine

197

1.09

0.07

2.1

2.7

—

(3026008) Bacteria identified in Urine by Culture

217

1.08

0.07

1.6

2.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

366

1.07

0.06

2.9

4.1

—

(3013115) Eosinophils [#/volume] in Blood

413

0.94

0.06

4.3

5.8

0.1

0.2

e9/l

1.91

369

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

150

0.92

0.04

1.4

2.3

380.0

634.3

u/l

0.24

145

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

160

0.93

0.04

1.7

1.5

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

1.11

0.04

1.1

1.8

—

(3006315) Basophils [#/volume] in Blood

400

0.96

0.03

3.9

5.7

0.0

e9/l

0.24

358

(3001604) Monocytes [#/volume] in Blood

398

0.96

0.02

3.9

5.7

0.5

e9/l

0.10

356

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

768

1.02

0.00

9.5

10.3

25.4

19.7

mg/l

0.72

551

(3002582) Erythrocytes [#/volume] in Urine

217

1.02

0.00

2.0

2.7

12.1

53.3

e6/l

1.44

173

(3031040) Bacteria [#/volume] in Urine by Automated count

515

1.02

0.00

2.5

3.9

—

50.0

—

(3037522) Nuclear Ab [Titer] in Serum

125

1.05

0.00

1.5

—

680.0

—

(3029937) Albumin [Presence] in Urine by Test strip

209

1.01

0.00

2.9

3.2

0.0

estimate

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.2

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

4.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.84

0.00

4.4

4.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

5.4

—

26.4

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.4

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.3

—

(36304052) Adalimumab Ab [Units/volume] in Serum or Plasma

0.00

0.0

5.2

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.5

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

2.1

—

(3015183) Erythrocyte sedimentation rate

0.00

0.0

1.0

—

(3020393) Adenovirus Ag [Presence] in Stool

0.00

0.0

3.8

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

0.84

0.00

6.2

9.7

3.4

1.0

mmol/l

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.0

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

8.8

—

0.6

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(42869547) Procollagen type III.N-terminal propeptide [Mass/volume] in Serum

0.00

0.0

1.0

—

6.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.2

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

0.0

1.1

—

0.3

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

0.0

3.3

—

6.4

—

(3020491) Glucose [Moles/volume] in Blood

0.00

0.0

1.3

—

5.5

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

3.3

—

1.0

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.4

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.1

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.92

0.00

1.2

1.5

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3041806) Other cells [#/volume] in Blood by Manual count

0.00

0.0

2.1

—

(40758990) Choriogonadotropin.beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.2

—

(3022145) Colonoscopy Study observation

0.87

0.00

1.3

1.5

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

1.2

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.1

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

0.0

1.4

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.4

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.0

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

0.0

1.1

—

107.6

—

(3026250) Tacrolimus [Mass/volume] in Blood

0.00

0.0

68.9

—

6.3

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3011985) Renin [Units/volume] in Plasma

0.00

0.0

1.0

—

38.5

—

(3010254) Herpes simplex virus identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

0.0

4.0

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.4

—

(3028772) Osteocalcin [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

80.8

—

(40768797) Stomach Pathology biopsy report

0.91

0.00

1.4

1.3

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_TURNE_SYNDR and mortality.

Females

Parameter	HR [95% CI]	p-value
Q17_TURNE_SYNDR	4.191 [3.01, 5.84]	< 0.001
Birth year	0.994 [0.99, 1.0]	0.156

During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 862 females with Q17_TURNE_SYNDR died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_TURNE_SYNDR.

N-year risk	Females	Males
1	0.364%	No data
5	2.293%	No data
10	5.834%	No data
15	10.872%	No data
20	18.565%	No data

Relationships between endpoints

↥

Index endpoint: Q17_TURNE_SYNDR – Turner's syndrome

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Turner's syndrome

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints