This is a non-core endpoint: only basic statistics are computed.

IPHG Phlebitis and thrombophlebitis of intracranial venous sinuses

I9_PHLETHROMBIC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G08 Hospital discharge: ICD-9 — 3259X Hospital discharge: ICD-8 — 32100 Cause of death: ICD-10 — G08 Cause of death: ICD-9 — 3259X Cause of death: ICD-8 — 32100 2 out of 7 registries used, show all original rules.	11
4. Check minimum number of events None	11
5. Include endpoints None	11
6. Filter based on genotype QC (FinnGen only)	11

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G00-G09
Name in latin: Phlebitis/thrombophlebitis intracranialis/intraspinalis

NAME	I9_PHLETHROMBIC
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G08
HD_ICD_9	3259X
HD_ICD_8	32100
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G08
COD_ICD_9	3259X
COD_ICD_8	32100
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to IPHG Phlebitis and thrombophlebitis of intracranial venous sinuses based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	206	119	82
Only index persons	149	94	55
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	38.40	36.55	39.95
Only index persons	31.20	32.03	29.79

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	11	9	-
Unadjusted period prevalence (%)	0.00	0.00	-
Median age at first event (years)	32.31	29.95	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

12.91

3.37

1.3

2.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

11.55

3.19

1.3

1.9

—

(3012516) Albumin [Mass/volume] in Urine

7.40

2.45

2.7

2.1

mg/l

42.4

103.3

—

(3033658) Prothrombin time (PT) actual/Normal

6.00

2.11

7.7

4.8

97.2

96.7

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

+∞

2.08

16.9

5.9

u/l

63.6

79.9

1.08

(3023368) Bacteria identified in Blood by Culture

6.63

2.08

2.4

8.9

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

4.19

1.47

1.6

2.4

mmol/l

0.8

0.9

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

3.93

1.39

1.2

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

1.18

0.0

1.6

—

(40758558) Short blood count panel - Blood

3.29

1.18

22.8

6.5

—

(42870588) Differential panel, method unspecified - Blood

3.31

1.12

15.3

4.6

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.91

0.0

1.3

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

2.54

0.80

1.8

4.3

g/l

37.2

36.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

+∞

0.68

4.9

3.6

mmol/l

6.2

5.7

0.78

(40768804) Tissue Pathology biopsy report

2.09

0.48

1.3

1.5

—

(3022096) Basophils/100 leukocytes in Blood

1.93

0.47

16.8

3.9

1.0

0.7

—

(3019069) Monocytes/100 leukocytes in Blood

1.93

0.47

16.7

4.0

8.2

8.0

—

(3006504) Eosinophils/100 leukocytes in Blood

1.93

0.47

17.2

3.9

1.8

3.2

—

(3018010) Neutrophils/100 leukocytes in Blood

1.86

0.46

13.7

3.9

50.8

55.4

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

+∞

0.45

6.1

4.4

mu/l

1.3

1.7

0.79

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

1.79

0.44

4.7

4.2

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

+∞

0.44

5.5

3.8

mmol/l

4.4

4.9

1.49

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.44

0.0

1.3

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

+∞

0.44

27.6

9.7

mmol/l

139.8

139.9

0.12

(3023103) Potassium [Moles/volume] in Serum or Plasma

+∞

0.44

27.8

9.8

mmol/l

3.9

0.46

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

1.64

0.29

3.2

4.4

mmol/l

1.2

—

(3019198) Lymphocytes [#/volume] in Blood

1.60

0.27

15.8

4.1

e9/l

2.1

1.7

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

0.00

0.22

0.0

2.0

—

0.7

—

(36660697) Celiac disease serology panel - Serum

0.00

0.22

0.0

1.0

—

(3000492) Spirometry study

0.00

0.22

0.0

1.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.22

0.0

2.0

—

(3002256) Pathology report gross observation

0.00

0.22

0.0

1.1

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.22

0.0

1.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.40

0.13

1.4

1.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.40

0.13

3.2

3.0

—

(3015736) pH of Urine

1.25

0.12

4.2

2.6

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

1.1

—

(4094501)

0.00

0.0

1.0

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

11.1

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.0

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

0.2

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

0.00

0.0

1.4

—

150.6

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

1.2

—

(3008898) HLA-B27 [Presence]

0.00

0.0

1.2

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.0

1.8

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.6

—

(40761535) Cells panel - Urine sediment

0.00

0.0

3.4

—

(3019060) Gas panel - Arterial blood

0.00

0.0

1.8

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.6

—

(3020779) Urea [Moles/volume] in Serum or Plasma

0.00

0.0

4.7

—

5.7

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.6

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.7

—

512.6

—

(3020961) Endomysium IgA Ab [Titer] in Serum

0.00

0.0

1.3

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.6

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.6

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.6

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.7

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.6

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.6

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.0

1.4

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

0.00

0.0

3.5

—

4.1

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint I9_PHLETHROMBIC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have I9_PHLETHROMBIC.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: I9_PHLETHROMBIC – IPHG Phlebitis and thrombophlebitis of intracranial venous sinuses

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

IPHG Phlebitis and thrombophlebitis of intracranial venous sinuses

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints