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Benign neoplasm: Skin of lower limb, including hip

CD2_BENIGN_SKIN_LOWERLIMB

skin neoplasm: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D23.7&
  • Hospital discharge: ICD-9 2167
  • Hospital discharge: ICD-8 21608
  • Hospital discharge: excluded ICD-9 2167A
  • Cause of death: ICD-10 D23.7&
  • Cause of death: ICD-9 2167
  • Cause of death: ICD-8 21608
  • Cause of death: excluded ICD-9 2167A

2 out of 7 registries used, show all original rules.

1005

4. Check minimum number of events

None

1005

5. Include endpoints

None

1005

6. Filter based on genotype QC (FinnGen only)

1005

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D23
Name in latin
Neoplasma benignum cutis pelvis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1005 628 377
Unadjusted period prevalence (%) 0.20 0.21 0.17
Median age at first event (years) 50.15 47.00 55.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
907
Matched controls
9067
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
1648.0
323.0
699
18
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
34.7
193.5
255
101
21608
ICD-8 Finland
Benign neoplasm of skin, Extremitatis inferioris
+∞
140.3
131
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.6
61.4
200
438
2167X
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,TARK MÄÄRITT HYVÄNLAAT KASV]
+∞
44.1
42
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.4
33.1
128
324
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
16.5
29.2
47
30
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
7.9
26.3
61
82
9733
FHL
Excision of skin change in operating room or anesthesia
10.5
24.5
48
48
2167G
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,MUU MÄÄR HYVÄNLAAT KASV]
+∞
24.1
23
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.8
20.0
89
254
L57.0
ICD-10 Finland
Actinic keratosis
3.1
19.9
119
426
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.1
19.5
112
390
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
3.9
18.2
78
216
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
8.2
17.9
40
51
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
5.8
16.8
48
87
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.3
16.6
51
101
XQ848
NOMESCO Finland
Dermatological photography
5.2
15.7
49
99
QDA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of lower limb
70.9
12.6
14
*
B07.9
ICD-10 Finland
Verruca simplex
4.1
12.4
48
122
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
5.7
12.2
34
61
TQW99
NOMESCO Finland
Other minor procedure on skin
3.1
11.9
65
219
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.0
11.6
151
805
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
15.3
11.3
18
12
ZXC50
NOMESCO Finland
Cryotherapy
4.1
11.3
43
108
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
21.7
10.7
15
7
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.3
10.4
37
88
Z94.0
ICD-10 Finland
Kidney transplant status
8.9
9.8
20
23
NHM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of ankle or foot
10.8
9.8
18
17
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
5.0
9.8
30
61
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
21.9
9.4
13
6
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
5.5
9.3
26
48
S18
ICPC
Laceration/cut
1.6
9.2
361
2688
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
6.8
9.2
22
33
TQW80
NOMESCO Finland
Local dermatologic skincare
3.8
9.1
37
100
D23.6
ICD-10 Finland
Benign neoplasm: Skin of upper limb, including shoulder
8.4
9.1
19
23
L82
ICD-10 Finland
Seborrhoeic keratosis
1.9
9.0
139
789
XQ845
NOMESCO Finland
Dermatoscopy
6.2
9.0
23
38
D23.9
ICD-10 Finland
Benign neoplasm: Skin, unspecified
4.3
8.9
32
77
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.6
8.9
63
250
127
Kela drug reimbursment
Transplant complication
5.2
8.8
26
51
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
3.9
8.8
35
93
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
12.9
8.4
14
11
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
8.2
148
881
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
14.6
8.2
13
9
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
3.9
8.2
32
84
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.9
7.9
31
82
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
7.9
153
937
J01DB01
ATC
cefalexin; oral
1.6
7.8
708
6280
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
7.7
356
2722
ZXC12
NOMESCO Finland
Pulse colorlaser
18.5
7.6
11
6
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.7
7.5
51
199
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
3.9
7.4
29
77
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
8.5
7.3
15
18
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
11.0
7.3
13
12
2167C
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,VERRUCA SEBORRHOICA]
+∞
7.3
7
*
SPAT1153
SPAT
Removal of sutures
1.5
7.2
274
1999
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
3.9
7.2
28
74
L04AA06
ATC
mycophenolic acid; systemic
4.3
7.1
25
60
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
8.0
7.1
15
19
L84
ICD-10 Finland
Corns and callosities
3.1
7.1
37
124
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
4.5
7.0
23
52
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
5.5
6.9
19
35
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.3
6.8
14
17
QDE15
NOMESCO Finland
Excision of other superficial lesion of skin in lower limb
40.3
6.8
8
*
C44.72
ICD-10 Finland
Spinocellular carcinoma of the skin of the lower extremity including the hip
12.3
6.6
11
9
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.6
6.5
46
185
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
14.4
6.4
10
7
J02AC01
ATC
fluconazole; systemic
1.4
6.3
339
2649
9734
FHL
Excision and local plastic or associated free skin grafting
9.3
6.3
12
13
E0000UV
ATC
NA
1.5
6.3
327
2537
J01FF01
ATC
clindamycin; systemic
1.5
6.3
224
1606
C43.73
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip nodular
26.9
6.2
8
*
A12AA04
ATC
calcium carbonate; oral
4.4
6.1
20
46
ZZA00
NOMESCO Finland
Split skin graft
3.3
6.0
28
87
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
6.0
52
233

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
512
3376
2.05
27.18
2.7
2.1
—
—
—
0
0
205
1059
2.18
19.91
1.4
1.3
—
—
—
0
0
390
2818
1.63
12.01
6.8
5.7
—
—
—
0
0
542
4241
1.60
11.98
7.3
5.8
1.9
1.9
e9/l
0.20
480
3733
532
4153
1.60
11.81
7.2
5.8
0.0
0.0
e9/l
0.03
468
3591
529
4135
1.59
11.59
7.1
5.7
0.6
0.6
e9/l
0.71
468
3567
544
4290
1.58
11.40
7.5
6.1
0.2
0.2
e9/l
0.39
485
3778
595
4794
1.59
11.35
9.9
9.2
4.0
4.1
e9/l
0.55
524
4203
516
4059
1.56
10.65
8.1
6.7
1.2
1.2
mmol/l
0.72
432
3415
722
6148
1.62
10.42
5.1
4.1
11.4
12.0
mm/h
0.67
672
5681
743
6400
1.62
9.93
9.1
7.5
77.4
78.3
u/l
0.18
707
6012
129
737
1.86
9.05
1.3
1.4
—
—
—
0
0
469
3705
1.50
8.91
6.9
5.9
1.2
1.2
mmol/l
0.36
430
3360
474
3761
1.49
8.77
8.0
5.9
0.7
0.7
%
0.22
444
3510
487
3887
1.49
8.74
7.8
5.9
2.9
2.8
%
0.18
456
3622
669
5699
1.52
8.70
5.5
4.3
—
—
—
0
0
489
3911
1.49
8.66
8.3
6.1
8.5
8.5
%
0.08
461
3664
492
3950
1.48
8.48
7.4
5.7
57.4
57.2
%
0.14
464
3702
903
8303
1.86
8.22
17.1
13.9
22.2
23.4
mg/l
0.47
735
6577
75
368
2.12
8.11
1.3
1.2
—
—
—
0
0
495
4002
1.47
8.10
7.9
6.0
28.4
27.9
%
0.37
468
3731
432
3524
1.40
6.15
6.0
4.6
35.8
35.6
g/l
0.40
400
3281
90
521
1.80
6.05
3.8
3.3
4.4
4.5
pmol/l
0.74
74
460
437
3608
1.37
5.63
3.2
2.7
108.2
119.3
ug/l
0.76
405
3346
559
4800
1.37
5.63
5.7
4.7
6.6
6.7
mmol/l
0.31
522
4508
513
4349
1.37
5.58
6.8
6.1
11.1
11.2
umol/l
0.05
495
4122
623
5454
1.37
5.50
5.2
4.4
40.2
2050.9
e6/l
—
5
78
314
2464
1.40
5.48
4.7
3.9
7.4
7.4
ph
0.07
55
482
266
2045
1.41
5.18
2.5
2.1
2.8
3.0
mg/l
0.92
223
1756
96
593
1.68
5.16
1.5
1.4
—
—
—
0
0
140
953
1.54
5.06
2.2
1.7
—
—
—
0
0
906
8535
1.62
5.02
19.4
16.0
4.0
4.0
mmol/l
0.30
887
8308
17
51
3.37
4.90
1.8
1.3
9.3
6.1
ug/l
0.50
17
41
829
7676
1.46
4.85
5.6
4.8
1.9
2.1
mu/l
0.54
769
7041
903
8515
1.60
4.80
19.2
15.9
139.9
139.7
mmol/l
1.96
886
8299
273
2133
1.38
4.79
3.4
2.5
8187.1
4905.6
umol/l
0.48
235
1836
198
1486
1.41
4.36
1.7
1.7
1267.4
1206.9
nmol/l
0.36
145
1113
959
9221
1.87
4.29
25.5
20.5
254.1
252.4
e9/l
0.37
944
9004
959
9224
1.87
4.24
25.4
20.4
90.8
91.0
fl
0.64
949
9099
297
2394
1.34
4.20
4.2
3.2
295.6
296.0
mg/l
0.00
175
1500
959
9227
1.86
4.19
25.6
20.5
6.7
6.7
e9/l
0.06
938
8984
313
2545
1.33
4.16
4.2
3.1
6.9
7.4
mmol/l
1.36
257
2134
959
9230
1.85
4.14
25.7
20.6
134.2
134.9
g/l
0.79
950
9102
926
8831
1.62
4.12
12.8
10.3
25.8
25.7
u/l
0.09
902
8536
958
9225
1.82
4.02
25.4
20.4
30.2
30.3
pg
1.41
948
9098
958
9226
1.82
4.00
25.6
20.5
4.5
4.5
e12/l
0.10
936
8987
146
1053
1.45
3.99
9.1
5.4
1.0
1.0
mmol/l
0.03
139
973
315
2592
1.31
3.80
2.6
2.5
54.2
56.7
u/l
0.79
296
2387
139
1009
1.44
3.67
1.8
1.4
—
—
—
0
0
388
3295
1.29
3.66
8.7
9.2
1.1
1.2
inr
1.36
105
965
306
2522
1.31
3.62
5.3
4.0
9.6
9.0
mg/mmol
0.10
185
1558
122
873
1.45
3.48
2.5
2.7
1.9
1.8
%
0.15
107
788
65
405
1.65
3.45
8.8
11.5
—
—
—
0
0
95
651
1.51
3.36
5.1
3.6
111.9
80.7
ng/l
1.97
86
577
461
4030
1.27
3.36
4.9
3.6
0.0
0.0
estimate
0.00
89
776
216
1712
1.33
3.34
3.3
2.5
4.0
6.4
e6/l
2.90
194
1516
8
14
5.75
3.34
4.6
2.6
—
—
—
0
0
257
2089
1.31
3.33
6.9
6.8
—
—
—
0
0
467
4096
1.26
3.29
5.0
3.6
0.0
0.0
estimate
0.80
95
760
702
6464
1.29
3.28
4.9
4.0
14.8
14.8
pmol/l
0.01
643
5896
808
7593
1.33
3.16
17.4
15.0
39.3
39.8
%
0.76
572
5456
195
1538
1.33
3.11
3.4
3.7
179.3
297.6
ng/l
0.83
138
1186
229
1850
1.31
3.08
5.3
4.6
—
—
—
0
0
34
181
1.91
3.08
1.1
1.5
312.9
772.8
e6/l
0.32
29
143
34
181
1.91
3.08
1.1
1.4
2.6
33.0
e6/l
0.98
26
137
32
168
1.93
3.02
1.2
1.5
—
—
—
0
0
203
1618
1.32
3.01
3.8
2.7
509.7
546.8
mosm/kgh2o
1.81
181
1390
460
4057
1.25
3.00
6.6
4.9
0.0
0.0
estimate
0.50
91
783
387
3349
1.25
2.98
2.0
2.0
95.1
95.6
pmol/l
0.07
204
1740
10
30
3.36
2.91
2.7
2.9
—
—
—
0
0
155
1196
1.35
2.86
2.2
2.0
—
—
—
0
0
31
165
1.91
2.83
5.1
3.6
56.5
58.6
%
0.54
31
165
107
778
1.42
2.82
2.8
2.1
310.5
368.5
nmol/l
2.76
98
720
332
2840
1.25
2.79
4.0
3.5
2.4
2.4
mmol/l
0.14
290
2497
307
2604
1.26
2.78
2.4
2.3
—
—
—
0
0
30
159
1.91
2.78
5.0
3.4
3.7
4.4
e9/l
1.91
30
159
125
940
1.38
2.72
3.2
2.7
9.1
8.2
umol/l
0.17
114
822
8
19
4.24
2.68
1.3
1.6
—
—
—
0
0
436
3860
1.23
2.64
4.3
4.0
—
—
—
0
0
118
889
1.37
2.55
7.8
8.3
5.1
5.1
kpa
0.11
112
855
118
889
1.37
2.55
7.8
8.3
12.3
12.2
kpa
0.01
112
858
334
2885
1.24
2.53
4.7
3.6
72.5
99.9
e6/l
0.40
248
2048
847
8075
1.31
2.52
5.1
4.5
6.0
5.9
mmol/l
0.21
779
7370
808
7661
1.28
2.48
6.8
5.7
39.9
39.8
mmol/mol
0.21
748
7122
90
651
1.42
2.47
3.2
2.8
79.3
71.6
e9/l
1.08
70
500
117
886
1.36
2.45
7.8
8.3
1.4
1.3
mmol/l
0.09
93
708
634
5867
1.22
2.37
4.4
3.8
—
—
—
0
0
61
413
1.51
2.35
2.8
2.4
—
—
—
0
0
162
1295
1.30
2.35
3.4
2.3
12.1
13.2
umol/l
1.30
152
1200
141
1106
1.32
2.34
3.6
2.4
21.3
22.9
%
0.83
124
952
737
6930
1.24
2.34
19.9
17.1
13.7
13.7
%
0.15
726
6798
144
1135
1.31
2.31
1.5
1.3
776.4
506.3
titre
0.58
39
246
258
2188
1.24
2.29
3.8
3.0
—
—
—
0
0
293
2520
1.23
2.28
3.2
3.0
—
—
—
0
0
873
8383
1.32
2.27
5.4
4.9
2.8
2.8
mmol/l
0.23
808
7726
285
2447
1.23
2.25
4.1
3.2
121.0
90.3
e6/l
0.11
227
1894
5
9
5.58
2.21
1.0
1.3
—
—
—
0
0
898
8663
1.34
2.21
16.7
13.1
—
—
—
0
0
17
80
2.14
2.19
1.2
1.6
—
—
—
0
0
182
1490
1.27
2.19
1.3
1.3
29.6
31.7
iu/ml
0.10
61
490
262
2242
1.23
2.13
3.9
3.0
0.3
0.4
e6/l
0.89
209
1699
256
2186
1.23
2.12
5.7
4.0
0.0
0.0
estimate
1.08
89
766
86
636
1.39
2.11
4.2
3.0
174.4
202.0
ng/l
0.35
81
582
42
269
1.59
2.09
3.0
1.5
0.2
0.2
g/l
0.87
37
253
283
2446
1.22
2.08
2.3
2.1
146.6
224.7
u/l
1.73
262
2305
38
239
1.61
2.04
2.6
3.4
—
—
—
0
0
412
3696
1.19
2.04
11.5
9.4
0.0
0.0
e9/l
1.08
348
3042
276
2386
1.22
2.02
4.1
3.8
—
—
—
0
0
857
8240
1.27
1.98
5.0
4.4
4.7
4.7
mmol/l
0.47
794
7637
260
2242
1.22
1.95
4.4
3.3
—
—
—
0
0
84
629
1.37
1.93
3.5
2.8
9.9
10.8
g/l
1.31
77
573
145
1176
1.27
1.89
1.3
1.2
—
—
—
0
0
77
571
1.38
1.88
4.2
2.8
4.5
4.1
e9/l
0.67
62
458
100
774
1.32
1.85
2.4
2.3
0.2
0.2
g/l
1.22
93
731
86
651
1.35
1.85
9.4
8.4
—
—
—
0
0
161
1327
1.25
1.84
4.1
3.2
0.8
0.8
mmol/l
0.11
150
1242
219
1869
1.22
1.81
1.9
1.7
1.1
1.1
mg/l
0.05
169
1433
12
53
2.28
1.81
4.2
6.9
—
—
—
0
0
70
515
1.39
1.80
4.5
5.5
—
—
—
0
0
117
930
1.29
1.80
1.5
1.3
—
—
—
0
0
851
8196
1.25
1.79
4.9
4.3
1.5
1.5
mmol/l
0.52
786
7553
824
7910
1.23
1.78
4.3
3.9
1.3
1.3
mmol/l
0.65
756
7250
145
1186
1.26
1.77
3.5
2.3
2.3
2.3
g/l
0.83
137
1100
190
1608
1.22
1.71
1.6
1.5
2.2
2.4
g/l
1.34
109
978
216
1853
1.21
1.70
5.1
3.6
—
—
—
0
0
91
708
1.31
1.65
4.7
3.9
—
—
—
0
0
239
2076
1.20
1.65
5.1
3.7
94.1
91.6
%
0.80
232
2022
5
14
3.58
1.61
1.2
1.3
—
—
—
0
0
216
1863
1.20
1.60
1.3
1.3
0.7
1.5
u/ml
1.65
54
515
259
2272
1.19
1.60
1.8
1.7
1.4
1.4
mmol/l
0.48
221
1904
135
1112
1.25
1.57
1.7
1.6
—
—
—
0
0
127
1039
1.25
1.56
29.2
21.7
1.1
1.3
inr
0.54
16
132
36
241
1.51
1.54
1.5
1.3
235.2
246.1
miu/ml
0.06
15
110
98
779
1.29
1.53
5.1
4.1
—
—
—
0
0
266
2349
1.18
1.51
3.3
3.0
1300.6
1249.3
ng/l
0.08
233
1998
227
1980
1.19
1.49
2.3
2.3
—
—
—
0
0
24
147
1.65
1.48
5.8
2.7
—
—
—
0
0
35
236
1.50
1.46
1.4
1.2
—
1216.3
—
0
8
92
731
1.28
1.45
4.4
3.5
2.2
2.0
mmol/l
0.34
75
588
6
22
2.74
1.43
1.2
1.1
—
16.8
%
—
0
5
6
22
2.74
1.43
2.3
1.5
—
—
—
0
0
206
1788
1.19
1.43
1.7
1.7
39306805.2
24949855.9
pmol/l
0.14
173
1483
20
118
1.71
1.42
1.3
1.3
0.6
0.6
nmol/l
0.22
20
112
10
46
2.19
1.40
1.1
1.2
—
—
—
0
0
111
913
1.24
1.33
2.0
1.5
—
—
—
0
0
6
24
2.51
1.30
1.0
1.4
—
—
—
0
0
85
681
1.27
1.28
4.5
3.3
—
—
—
0
0
75
592
1.29
1.27
1.2
1.2
86.1
139.1
iu/ml
1.41
30
245
39
278
1.42
1.26
4.4
3.2
0.2
0.2
g/l
0.20
22
108
245
2182
1.16
1.25
4.8
4.2
—
—
—
0
0
20
123
1.64
1.24
1.2
1.2
—
—
—
0
0
6
25
2.41
1.24
1.0
1.4
—
—
—
0
0
6
25
2.41
1.24
2.0
1.2
1.8
4.1
mmol/l
—
6
20
6
25
2.41
1.24
1.0
1.1
1907.8
1610.4
miu/ml
—
6
25
13
71
1.84
1.19
1.1
1.1
—
—
—
0
0
148
1269
1.19
1.19
3.3
2.8
2.2
2.4
e6/l
0.18
86
689
6
26
2.32
1.19
1.0
1.4
—
—
—
0
0
18
110
1.65
1.16
1.1
1.3
—
—
—
0
0
15
87
1.74
1.15
2.3
2.8
—
—
—
0
0
64
506
1.28
1.09
2.4
1.7
1.0
1.5
g/l
2.05
55
464
40
295
1.37
1.09
1.8
1.9
20.5
21.1
s
0.55
35
264
85
696
1.24
1.09
8.3
7.3
1.1
1.3
mmol/l
2.01
80
665
21
138
1.53
1.03
1.2
1.2
—
—
—
0
0
11
60
1.84
1.03
1.0
1.1
—
—
—
0
0
7
34
2.07
1.03
2.9
3.1
—
—
—
0
0
161
1417
1.16
0.97
1.3
1.3
15.9
11.6
u/ml
0.30
73
535
18
116
1.56
0.97
2.6
2.3
5.4
39.1
u/ml
0.49
18
109
46
355
1.31
0.96
1.3
1.9
1.5
1.5
g/l
0.11
40
311
13
77
1.70
0.95
1.1
1.2
—
—
—
0
0
9
51
1.77
0.94
1.1
1.2
—
—
—
0
0
16
101
1.59
0.94
1.9
1.2
—
57.1
—
0
7
32
235
1.37
0.92
1.9
2.0
973.2
2929.5
u/l
0.75
11
88
40
305
1.32
0.92
5.3
4.3
—
—
—
0
0
65
529
1.24
0.91
1.2
1.2
—
—
—
0
0
17
110
1.55
0.91
3.8
1.9
33.1
32.3
pg
0.28
17
110
246
2241
1.13
0.91
5.0
5.0
2.0
2.5
ug/l
0.91
219
1994
78
648
1.22
0.90
1.2
1.2
—
—
—
0
0
6
29
2.08
0.89
2.2
3.5
—
—
—
0
0
216
1954
1.13
0.89
1.5
1.5
21.6
21.2
nmol/l
0.14
191
1673
338
3142
1.11
0.88
4.0
3.5
29.5
48.9
ng/l
0.93
218
2148
14
87
1.62
0.88
3.9
4.7
44.7
54.2
u/ml
—
6
27
16
103
1.56
0.87
1.2
1.3
—
—
nmol/l
—
0
0
77
643
1.21
0.86
1.8
1.6
—
—
—
0
0
63
515
1.24
0.86
2.2
2.2
14.9
13.0
nmol/l
0.96
57
454
195
1758
1.14
0.85
5.7
4.0
1.0
1.0
kg/l
0.78
28
243
23
162
1.43
0.85
2.7
2.1
125.1
128.3
g/l
0.23
16
123
10
57
1.76
0.84
1.0
1.0
—
—
—
0
0
12
189
0.63
0.82
2.3
2.2
—
—
—
0
0
12
73
1.65
0.82
1.1
1.2
—
—
—
0
0
13
81
1.61
0.81
1.2
1.1
—
—
—
0
0
19
130
1.47
0.81
1.7
1.3
—
—
—
0
0
18
122
1.48
0.80
1.2
1.2
—
—
—
0
0
76
640
1.20
0.79
6.0
4.0
0.7
0.5
%
0.13
15
153
69
577
1.21
0.77
1.7
1.4
—
—
—
0
0
31
235
1.33
0.76
1.8
2.3
10.4
11.9
mg/l
0.65
31
216
82
700
1.19
0.75
5.9
4.1
1.2
1.0
%
0.14
20
210
99
859
1.17
0.75
4.3
3.9
14.0
25.1
ug/l
0.41
82
708
23
167
1.39
0.74
5.0
4.0
2.6
2.8
mmol/l
0.06
17
114
73
618
1.20
0.73
6.4
4.2
0.0
0.7
%
0.65
15
158
12
76
1.59
0.72
1.7
1.3
—
—
—
0
0
27
203
1.34
0.71
4.7
3.7
7.4
7.4
ph
0.44
22
165
5
26
1.93
0.70
2.6
2.0
—
—
—
0
0
7
41
1.71
0.70
2.6
3.1
311.6
1166.2
u/ml
—
7
41
7
43
1.63
0.67
1.3
1.3
144.9
145.5
nmol/l
—
7
43
13
86
1.52
0.66
1.1
1.7
—
—
—
0
0
112
992
1.15
0.66
2.0
2.2
102.6
133.3
ug/g
0.58
92
785
7
44
1.59
0.65
1.0
1.0
—
—
—
0
0
149
1348
1.12
0.64
1.9
1.8
—
—
—
0
0
46
378
1.23
0.64
1.2
1.3
26.7
29.9
iu/l
0.27
38
318
5
29
1.73
0.64
1.0
1.2
50.6
36.4
g/l
—
5
19
8
131
0.61
0.63
1.3
1.6
—
—
—
0
0
23
302
0.76
0.63
1.0
1.1
—
—
—
0
0
56
471
1.20
0.62
1.5
1.3
—
—
—
0
0
77
667
1.17
0.62
3.2
3.0
66.6
67.0
g/l
0.18
68
611
18
130
1.39
0.61
1.2
1.2
1.8
7.2
u/ml
—
6
51
13
88
1.48
0.60
2.2
1.8
—
—
—
0
0
78
678
1.16
0.60
5.0
3.7
1.2
1.2
mmol/l
0.07
69
594
37
299
1.25
0.60
1.7
1.6
—
—
—
0
0
20
148
1.36
0.60
3.2
2.5
—
—
—
0
0
25
192
1.31
0.59
1.6
1.7
45.1
40.5
nmol/l
0.51
25
185
44
364
1.22
0.58
1.1
1.1
—
—
—
0
0
167
1530
1.11
0.58
2.9
2.9
2.5
2.5
mmol/l
0.10
142
1347
22
167
1.32
0.57
4.2
3.7
—
—
—
0
0
13
90
1.45
0.55
2.5
1.1
—
—
—
0
0
19
142
1.34
0.54
1.6
1.4
—
—
—
0
0
9
60
1.50
0.54
1.2
1.1
—
—
—
0
0
14
99
1.42
0.54
2.1
1.7
—
—
—
0
0
18
134
1.35
0.53
1.0
1.1
—
—
—
0
0
6
39
1.54
0.53
1.8
1.7
1.7
6.5
nmol/l
—
6
30
6
99
0.60
0.52
1.0
1.3
—
—
—
0
0
75
660
1.15
0.51
6.3
4.2
0.1
0.2
%
0.82
17
189
28
224
1.26
0.51
1.5
1.3
—
—
—
0
0
19
144
1.33
0.51
1.5
1.3
57.8
60.6
mmol/l
0.09
12
121
9
65
1.39
0.50
1.7
3.7
12.3
10.7
%
—
9
65
6
41
1.47
0.50
1.0
1.0
—
—
—
0
0
38
317
1.21
0.49
3.2
3.1
3198.9
1114.7
u/ml
0.28
30
272
11
76
1.45
0.48
1.5
1.3
44327.8
124677.6
e6/l
—
6
42
70
791
0.88
0.47
1.2
1.4
—
—
—
0
0
12
85
1.42
0.47
2.3
2.2
—
—
—
0
0
24
191
1.26
0.46
2.8
2.7
7.8
8.1
kpa
0.31
24
174
34
406
0.83
0.45
4.7
3.6
—
—
—
0
0
18
138
1.31
0.45
1.0
1.1
—
—
—
0
0
7
51
1.38
0.44
3.7
1.6
—
—
—
0
0
64
565
1.14
0.44
2.5
2.5
—
—
—
0
0
232
2191
1.08
0.43
1.4
1.4
—
—
—
0
0
10
140
0.71
0.43
1.3
1.6
—
—
—
0
0
27
221
1.23
0.42
2.1
1.8
4.4
5.1
iu/l
0.16
11
75
99
903
1.11
0.41
1.6
1.7
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
—
93.8
—
0
8
45
390
1.16
0.40
4.6
3.6
24.8
24.3
mmol/l
0.41
38
349
74
665
1.12
0.40
2.5
2.4
6.0
7.3
ug/l
0.36
62
587
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
26
216
1.21
0.37
1.7
1.2
9.3
2.5
u/ml
—
6
24
24
198
1.22
0.36
1.3
1.3
9.6
12.1
u/l
0.42
18
159
9
71
1.27
0.36
5.0
1.9
—
1.3
—
0
5
22
180
1.23
0.36
2.5
1.7
—
—
—
0
0
89
814
1.10
0.36
1.4
1.5
—
—
—
0
0
26
217
1.20
0.35
1.4
1.2
—
—
—
0
0
290
3021
0.94
0.35
2.9
2.8
—
—
—
0
0
59
528
1.12
0.35
3.3
2.8
—
—
—
0
0
16
127
1.26
0.33
1.1
1.2
—
—
—
0
0
6
46
1.31
0.33
2.2
2.0
—
51.3
—
0
5
6
46
1.31
0.33
1.0
1.2
—
—
—
0
0
21
252
0.83
0.32
14.4
9.7
—
—
—
0
0
13
165
0.79
0.32
1.5
1.3
—
—
—
0
0
10
75
1.34
0.30
1.0
1.3
—
—
—
0
0
11
84
1.31
0.30
1.3
1.6
—
—
—
0
0
8
66
1.21
0.26
1.5
1.4
—
—
—
0
0
11
136
0.81
0.23
1.1
1.1
0.7
2.2
u/ml
—
5
52
5
39
1.28
0.23
1.2
1.4
—
—
—
0
0
81
758
1.07
0.22
1.5
1.4
—
—
—
0
0
11
88
1.25
0.22
1.5
1.1
—
—
—
0
0
5
41
1.22
0.22
1.2
1.0
—
4.2
—
0
5
16
135
1.19
0.21
2.1
1.3
118.0
111.9
u/ml
—
5
28
5
42
1.19
0.21
2.0
2.5
—
—
—
0
0
0
11
0.00
0.21
0.0
13.1
—
0.2
—
0
11
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
15
177
0.85
0.21
2.2
3.4
—
—
—
0
0
0
13
0.00
0.21
0.0
2.7
—
—
—
0
0
0
13
0.00
0.21
0.0
9.9
—
—
—
0
0
0
13
0.00
0.21
0.0
5.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
49
1.23
0.20
1.0
1.1
—
—
—
0
0
42
457
0.92
0.19
2.1
1.7
—
—
—
0
0
10
81
1.24
0.18
2.0
2.6
—
—
—
0
0
21
238
0.88
0.18
1.4
1.3
—
—
—
0
0
10
121
0.82
0.18
1.5
1.4
—
—
—
0
0
23
258
0.89
0.18
1.4
1.3
—
—
—
0
0
57
533
1.07
0.17
5.5
3.4
7.4
7.4
ph
—
10
65
23
257
0.89
0.17
1.4
1.3
—
—
—
0
0
15
129
1.17
0.17
1.1
1.1
—
—
—
0
0
28
253
1.11
0.17
1.5
2.2
37.0
38.1
g/l
0.35
23
224
37
340
1.09
0.16
2.0
1.9
2.6
2.0
ug/l
0.13
32
306
6
77
0.78
0.15
2.2
1.3
5.5
6.9
mmol/l
—
6
70
30
274
1.10
0.15
1.8
1.6
500.4
302.6
mu/l
0.84
25
249
9
78
1.16
0.15
1.2
1.3
—
—
—
0
0
23
255
0.90
0.15
1.4
1.3
—
—
—
0
0
23
255
0.90
0.15
1.4
1.3
—
—
—
0
0
9
79
1.14
0.15
1.7
1.4
—
—
—
0
0
9
82
1.10
0.15
7.2
2.2
—
—
—
0
0
21
188
1.12
0.15
6.8
4.1
—
—
—
0
0
10
116
0.86
0.12
1.4
1.4
—
—
—
0
0
10
116
0.86
0.12
1.4
1.4
—
—
—
0
0
18
162
1.11
0.12
3.9
2.4
15.4
16.0
%
0.27
12
84
15
168
0.89
0.11
1.5
1.7
—
—
—
0
0
16
143
1.12
0.11
1.1
1.2
—
—
—
0
0
5
47
1.06
0.09
1.2
1.9
—
—
—
0
0
11
97
1.14
0.09
4.9
2.8
—
—
—
0
0
6
57
1.05
0.08
1.2
2.4
—
—
—
0
0
34
359
0.95
0.08
1.9
1.9
—
—
—
0
0
13
144
0.90
0.08
1.2
1.2
261.9
26.6
u/l
—
7
129
21
226
0.93
0.08
1.0
1.1
—
—
—
0
0
30
283
1.06
0.08
5.3
3.8
1.1
1.3
mmol/l
0.86
30
276
7
65
1.08
0.08
2.1
1.6
1.0
1.0
g/l
—
7
65
11
98
1.12
0.07
1.9
1.2
—
—
—
0
0
7
82
0.85
0.07
5.9
3.6
—
—
—
0
0
7
83
0.84
0.07
1.1
1.2
—
—
—
0
0
8
90
0.89
0.06
2.0
3.8
—
—
—
0
0
9
104
0.86
0.06
1.1
1.5
—
—
—
0
0
51
493
1.04
0.06
1.4
1.4
—
—
—
0
0
14
129
1.09
0.05
1.1
1.1
—
—
—
0
0
27
257
1.05
0.05
1.4
1.2
—
—
—
0
0
16
149
1.08
0.05
1.6
1.2
339.2
280.9
u/ml
—
9
89
25
238
1.05
0.05
6.2
3.8
3.8
3.9
mmol/l
0.49
25
219
11
101
1.09
0.04
1.9
1.4
30.8
32.3
g/l
0.19
11
90
22
210
1.05
0.03
4.4
4.8
—
—
—
0
0
13
122
1.07
0.02
1.7
3.3
1.0
1.3
%
0.17
13
103
16
152
1.05
0.02
2.2
1.4
—
—
—
0
0
18
173
1.04
0.01
3.0
3.7
18.8
27.4
mg/l
0.60
12
106
20
194
1.03
0.00
2.9
2.4
340.3
90.6
ug/min
0.50
11
119
26
254
1.02
0.00
1.1
1.2
—
—
—
0
0
32
316
1.01
0.00
2.5
2.6
—
—
—
0
0
10
98
1.02
0.00
4.1
2.4
—
—
—
0
0
14
138
1.01
0.00
1.1
1.3
—
—
—
0
0
130
1304
1.00
0.00
3.0
3.0
0.7
0.8
ug/l
0.09
82
859
15
147
1.02
0.00
1.1
1.6
—
—
—
0
0
13
127
1.02
0.00
1.0
1.5
—
—
—
0
0
19
191
0.99
0.00
1.1
1.4
—
—
—
0
0
11
109
1.01
0.00
5.1
2.4
—
—
—
0
0
39
395
0.99
0.00
6.5
3.3
—
—
—
0
0
24
235
1.02
0.00
1.8
1.5
285.3
283.5
ug/g
0.02
17
138
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
0.00
1.7
1.4
—
—
—
0
0
10
100
1.00
0.00
4.1
2.4
3.9
4.1
mmol/l
—
10
100
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
100.0
—
0
5
9
93
0.97
0.00
1.9
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
0.00
1.9
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
7
78
0.90
0.00
2.3
1.6
—
—
—
0
0
9
93
0.97
0.00
1.9
1.6
—
—
—
0
0
7
79
0.89
0.00
2.4
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
5.7
—
—
—
0
0
10
100
1.00
0.00
4.1
2.4
105.3
105.3
mmol/l
—
10
100
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
8
82
0.98
0.00
1.1
1.2
—
—
—
0
0
9
93
0.97
0.00
1.9
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
17.4
—
0
9
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_SKIN_LOWERLIMB – Benign neoplasm: Skin of lower limb, including hip

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).