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Benign neoplasm: Skin of lower limb, including hip

CD2_BENIGN_SKIN_LOWERLIMB

skin neoplasm: A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D23.7&
  • Hospital discharge: ICD-9 2167
  • Hospital discharge: ICD-8 21608
  • Hospital discharge: excluded ICD-9 2167A
  • Cause of death: ICD-10 D23.7&
  • Cause of death: ICD-9 2167
  • Cause of death: ICD-8 21608
  • Cause of death: excluded ICD-9 2167A

2 out of 7 registries used, show all original rules.

1054

4. Check minimum number of events

None

1054

5. Include endpoints

None

1054

6. Filter based on genotype QC (FinnGen only)

1028

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D23
Name in latin
Neoplasma benignum cutis pelvis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1028 639 389
Unadjusted period prevalence (%) 0.21 0.23 0.18
Median age at first event (years) 50.86 47.71 56.04

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1054
Matched controls
10540
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
26.6
307.7
297
153
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
2028.7
307.7
828
19
21608
ICD-8 Finland
Benign neoplasm of skin, Extremitatis inferioris
+∞
154.0
144
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.2
97.6
240
569
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
34.1
81.2
52
16
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.3
51.4
149
393
2167X
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,TARK MÄÄRITT HYVÄNLAAT KASV]
+∞
46.2
44
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.9
38.9
125
353
9733
FHL
Excision of skin change in operating room or anesthesia
8.4
37.8
50
62
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
5.7
36.6
71
133
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
6.0
34.9
63
110
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
7.0
33.4
52
78
XQ848
NOMESCO Finland
Dermatological photography
5.3
30.7
64
128
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.0
28.0
136
495
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
3.6
27.6
95
280
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.4
27.4
55
106
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.3
27.0
254
1276
2167G
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,MUU MÄÄR HYVÄNLAAT KASV]
+∞
26.1
25
*
L57.0
ICD-10 Finland
Actinic keratosis
2.7
25.7
154
627
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
5.2
24.6
52
105
127
Kela drug reimbursment
Transplant complication
7.1
21.7
33
48
XQ845
NOMESCO Finland
Dermatoscopy
5.8
21.3
39
69
TQW99
NOMESCO Finland
Other minor procedure on skin
3.2
19.8
81
266
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
4.7
19.8
46
101
ZXC50
NOMESCO Finland
Cryotherapy
4.2
19.4
53
132
B07.9
ICD-10 Finland
Verruca simplex
3.7
17.9
58
164
D23.9
ICD-10 Finland
Benign neoplasm: Skin, unspecified
4.8
17.6
40
86
L04AA06
ATC
mycophenolic acid; systemic
5.3
15.9
32
62
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
4.2
14.3
38
93
TQW80
NOMESCO Finland
Local dermatologic skincare
4.0
13.9
40
104
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.9
13.8
68
248
D23.6
ICD-10 Finland
Benign neoplasm: Skin of upper limb, including shoulder
6.6
13.7
22
34
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
4.4
12.9
32
74
S18
ICPC
Laceration/cut
1.6
12.7
477
3571
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
4.2
12.4
33
81
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
14.5
12.3
20
14
QDA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of lower limb
21.6
12.0
17
8
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
3.3
11.9
44
136
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
3.9
11.7
34
89
D21.2
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of lower limb, including hip
23.2
11.6
16
7
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
4.7
11.5
26
56
L82
ICD-10 Finland
Seborrhoeic keratosis
1.8
11.1
195
1189
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
3.6
10.9
36
103
Z94.0
ICD-10 Finland
Kidney transplant status
8.4
10.8
23
28
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.0
10.8
30
76
ZXC15
NOMESCO Finland
Use of photodynamic technique
4.8
10.3
23
49
L04AD01
ATC
ciclosporin; systemic
4.2
10.2
27
66
J01DB01
ATC
cefalexin; oral
1.7
9.9
850
7513
SPAT1153
SPAT
Removal of sutures
1.6
9.5
326
2350
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.1
9.3
39
130
L04AA01
ATC
[U] ciclosporin
4.7
9.3
21
45
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
10.8
9.3
17
16
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.8
9.2
28
76
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
4.8
9.1
20
42
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
8.9
453
3541
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
2.2
8.8
77
370
D18.0
ICD-10 Finland
Haemangioma, any site
3.4
8.7
31
94
E0000UV, ,
ATC
1.5
8.7
411
3164
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
4.6
8.6
20
44
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
9.1
8.5
17
19
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.6
8.5
201
1322
L04AD02
ATC
tacrolimus; systemic
7.1
8.3
19
27
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
7.1
8.3
19
27
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
14.6
8.2
13
9
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.6
8.2
26
73
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
7.3
8.0
18
25
D06BX02
ATC
ingenol mebutate; topical
4.5
7.9
19
43
A12AA04
ATC
calcium carbonate; oral
4.0
7.9
22
56
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.7
7.9
18
39
NHM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of ankle or foot
7.0
7.8
18
26
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
7.0
7.8
18
26
D22
ICD-10 Finland
Melanocytic naevi
2.4
7.8
53
229
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
7.7
215
1470
A11CC03
ATC
alfacalcidol; systemic
3.2
7.7
29
91
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.0
7.6
87
461
J02AC01
ATC
fluconazole; systemic
1.5
7.6
393
3056
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
7.6
181
1193
C44.72
ICD-10 Finland
Spinocellular carcinoma of the skin of the lower extremity including the hip
10.1
7.5
14
14
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
7.2
7.5
17
24
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
7.4
62
292
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
7.4
350
2675
2167C
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,VERRUCA SEBORRHOICA]
+∞
7.3
7
*
C43.73
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip nodular
20.2
7.1
10
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
7.1
125
759
UJF32
NOMESCO Finland
Coloscopy
1.5
7.1
251
1806
L84
ICD-10 Finland
Corns and callosities
2.5
7.1
42
170
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
10.1
7.0
13
13
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
7.0
7.0
16
23
ZZA00
NOMESCO Finland
Split skin graft
2.8
7.0
35
130
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.1
6.8
63
310
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.2
6.8
56
263
ZXA00
NOMESCO Finland
Right side
1.5
6.7
261
1914
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
6.5
6.6
16
25
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
7.9
6.6
14
18
M03BX02
ATC
tizanidine; oral
1.4
6.5
615
5272
D07AC01
ATC
betamethasone; topical
1.4
6.5
345
2681
QAE15
NOMESCO Finland
Excision of other superficial lesion of skin from head and neck
70.3
6.4
7
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.4
699
6134
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
3.8
6.4
19
51
SPAT1260
SPAT
Consultation of another employee
1.6
6.4
163
1090
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.1
6.3
25
81
2167D
ICD-9 Finland
Benign neoplasm of skin, Skin of lower limb, including hip[ALARAAJAN IHON BEN KASV,MUU EPIDERM JA KARVAFOLL KA]
+∞
6.3
6
*
D07XC01
ATC
betamethasone; topical
1.7
6.2
116
716
SPAT1301
SPAT
No procedures
1.4
6.1
292
2221
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
12.6
6.1
10
8
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
6.1
218
1569
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
10.1
6.0
11
11
TQW40
NOMESCO Finland
Remowal of suture of skin
1.9
6.0
73
396

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
550
3542
2.16
32.45
2.7
2.1
—
—
—
0
0
229
1115
2.35
26.13
1.4
1.3
—
—
—
0
0
534
4120
1.60
12.47
8.0
6.2
—
—
—
0
0
545
4249
1.59
12.00
8.6
6.7
1.21
1.21
mmol/l
0.73
459
3609
556
4365
1.58
11.80
7.4
5.7
0.04
0.04
e9/l
0.09
491
3783
566
4469
1.58
11.67
7.6
5.7
1.89
1.92
e9/l
0.24
505
3958
760
6436
1.65
11.63
5.1
4.1
11.32
12.01
mm/h
0.83
707
5953
569
4511
1.57
11.43
7.7
6.0
0.21
0.19
e9/l
0.35
509
3977
553
4356
1.57
11.42
7.4
5.7
0.56
0.58
e9/l
1.05
491
3772
623
5044
1.58
11.39
10.6
9.1
3.96
4.09
e9/l
0.76
551
4426
781
6696
1.64
10.99
9.5
7.4
77.10
78.51
u/l
0.32
745
6301
137
766
1.91
10.27
1.4
1.4
—
—
—
0
0
495
3873
1.52
10.08
7.2
6.0
1.21
1.21
mmol/l
0.39
455
3536
701
5963
1.52
9.21
5.5
4.3
—
—
—
0
0
949
8708
1.90
9.01
17.7
13.8
22.04
23.39
mg/l
0.60
776
6893
496
3957
1.48
8.77
8.2
5.9
0.69
0.68
%
0.14
465
3695
513
4126
1.47
8.67
8.7
6.1
8.47
8.51
%
0.12
484
3868
510
4099
1.47
8.64
8.1
5.8
2.84
2.83
%
0.03
480
3840
79
388
2.12
8.50
1.3
1.2
—
—
—
0
0
515
4171
1.46
8.25
7.7
5.7
57.46
57.24
%
0.17
487
3917
519
4224
1.45
8.02
8.2
5.9
28.25
27.87
%
0.36
492
3967
548
4546
1.43
7.41
7.1
6.2
11.11
11.18
umol/l
0.05
529
4315
458
3686
1.43
7.29
6.4
4.7
35.94
35.66
g/l
0.49
424
3439
335
2574
1.44
6.75
4.9
3.9
7.40
7.40
ph
0.04
59
504
592
5028
1.40
6.72
6.0
4.8
6.60
6.68
mmol/l
0.44
555
4720
94
546
1.79
6.23
3.7
3.3
4.43
4.56
pmol/l
0.66
78
485
459
3805
1.37
5.69
3.3
2.7
108.48
117.99
ug/l
0.64
426
3528
150
1010
1.57
5.67
2.2
1.7
—
—
—
0
0
874
8060
1.49
5.61
5.6
4.8
1.88
2.05
mu/l
0.58
812
7407
651
5708
1.37
5.59
5.2
4.4
40.20
2164.33
e6/l
—
5
86
951
8940
1.65
5.55
19.9
16.0
3.97
3.96
mmol/l
0.24
932
8706
947
8920
1.61
5.15
19.7
15.9
139.88
139.67
mmol/l
1.93
930
8697
277
2152
1.39
5.01
2.4
2.1
2.80
3.01
mg/l
0.93
233
1839
286
2237
1.38
4.96
3.7
2.5
7748.39
5037.94
umol/l
0.40
249
1947
159
1119
1.50
4.90
9.5
5.4
1.03
1.03
mmol/l
0.05
149
1034
98
619
1.64
4.84
1.6
1.4
—
—
—
0
0
469
3987
1.32
4.60
15.7
14.0
1.13
1.24
inr
2.30
132
1170
1007
9680
1.90
4.58
26.3
20.5
44.47
40.09
%
0.47
945
9060
335
2717
1.34
4.54
2.7
2.5
54.72
88.51
u/l
0.60
316
2512
1007
9683
1.90
4.53
26.1
20.4
253.88
252.35
e9/l
0.33
992
9462
1007
9686
1.89
4.48
26.0
20.4
90.80
90.99
fl
0.67
997
9559
10
15
6.72
4.47
5.7
2.6
—
—
—
0
0
1007
9692
1.87
4.38
26.2
20.5
134.37
135.01
g/l
0.74
998
9562
311
2506
1.34
4.38
4.3
3.2
502.88
308.30
mg/l
0.25
186
1587
17
55
3.13
4.37
1.8
1.3
9.30
5.97
ug/l
0.52
17
43
972
9269
1.63
4.34
13.1
10.3
25.70
25.76
u/l
0.03
948
8964
431
3643
1.31
4.33
2.5
2.2
77.92
77.47
nmol/l
0.12
392
3267
149
1062
1.47
4.30
1.9
1.4
—
—
—
0
0
36
172
2.13
4.27
5.2
3.6
55.94
58.23
%
0.61
36
172
1006
9687
1.85
4.26
26.0
20.3
30.16
30.28
pg
1.50
996
9558
1006
9687
1.85
4.26
26.1
20.4
6.65
6.68
e9/l
0.21
985
9438
1006
9688
1.84
4.24
26.1
20.4
4.48
4.48
e12/l
0.05
984
9444
101
669
1.56
4.12
5.0
3.6
109.55
80.55
ng/l
1.86
90
594
326
2668
1.32
4.08
4.1
3.1
7.01
7.46
mmol/l
1.19
268
2250
202
1547
1.38
3.90
1.7
1.7
1250.65
1202.98
nmol/l
0.27
148
1158
34
165
2.10
3.90
5.0
3.3
3.68
4.43
e9/l
2.27
34
165
493
4292
1.28
3.79
5.0
3.6
0.00
0.01
estimate
0.80
101
792
70
433
1.66
3.79
10.1
11.7
—
—
—
0
0
487
4236
1.28
3.76
5.0
3.7
0.00
0.00
estimate
0.50
100
864
228
1794
1.35
3.70
3.5
2.5
4.69
6.38
e6/l
1.36
211
1627
207
1607
1.36
3.66
3.5
3.7
778.52
314.76
ng/l
0.36
146
1237
354
2968
1.29
3.63
4.1
3.4
2.35
2.35
mmol/l
0.21
315
2631
486
4250
1.27
3.52
6.7
4.9
0.00
0.00
estimate
0.50
97
815
318
2641
1.29
3.49
5.1
3.8
10.36
8.86
mg/mmol
0.26
191
1636
464
4042
1.26
3.45
2.7
2.5
—
—
—
0
0
735
6765
1.29
3.43
4.9
4.0
14.76
14.74
pmol/l
0.07
674
6178
134
978
1.42
3.42
3.4
2.7
8.90
8.40
umol/l
0.09
121
854
407
3500
1.27
3.34
1.9
2.0
94.15
95.33
pmol/l
0.19
215
1821
127
923
1.43
3.32
2.7
2.7
1.86
1.82
%
0.19
111
832
326
2732
1.28
3.30
2.4
2.3
—
—
—
0
0
114
815
1.45
3.26
2.8
2.1
306.96
371.90
nmol/l
3.57
105
754
9
19
4.77
3.24
1.9
1.6
—
—
—
0
0
268
2196
1.30
3.23
7.2
6.7
—
—
—
0
0
216
1720
1.32
3.21
4.1
2.8
499.03
540.97
mosm/kgh2o
2.39
194
1493
892
8459
1.35
3.15
5.1
4.5
5.94
5.92
mmol/l
0.17
820
7724
164
1260
1.36
3.09
2.2
2.0
—
—
—
0
0
35
189
1.88
3.04
1.1
1.4
2.85
31.50
e6/l
0.96
27
144
35
189
1.88
3.04
1.1
1.5
302.57
741.63
e6/l
0.32
30
150
806
7554
1.28
2.98
20.3
16.7
14.68
14.90
%
0.55
795
7434
391
3385
1.25
2.95
4.2
3.4
5.54
5.83
ph
0.63
27
264
12
37
3.27
2.94
1.1
1.1
—
80.83
%
—
0
6
33
177
1.89
2.94
1.2
1.5
—
—
—
0
0
352
3019
1.25
2.87
4.8
3.6
71.47
96.03
e6/l
0.37
262
2137
848
8015
1.30
2.83
6.8
5.6
39.88
39.74
mmol/mol
0.18
785
7459
126
944
1.38
2.79
8.5
8.5
12.29
12.18
kpa
0.09
120
912
126
944
1.38
2.79
8.5
8.5
5.09
5.12
kpa
0.11
120
909
667
6138
1.24
2.77
4.4
3.7
—
—
—
0
0
12
43
2.81
2.65
1.2
1.4
159.92
177.27
mmol/24h
0.36
12
43
436
3853
1.22
2.64
12.0
9.4
0.00
0.00
e9/l
1.12
371
3171
175
1390
1.31
2.64
4.7
3.2
0.82
0.81
mmol/l
0.04
164
1307
125
945
1.37
2.62
8.5
8.5
1.45
1.26
mmol/l
0.30
100
767
7
15
4.69
2.60
1.3
1.5
—
—
—
0
0
95
688
1.42
2.57
3.5
2.8
81.03
71.51
e9/l
1.40
73
526
192
1552
1.29
2.54
1.3
1.3
28.10
31.58
iu/ml
0.20
66
516
10
31
3.25
2.52
2.7
2.9
—
—
—
0
0
301
2569
1.24
2.52
2.4
2.1
143.81
251.28
u/l
1.97
278
2420
301
2571
1.24
2.50
4.2
3.1
115.86
86.91
e6/l
0.11
240
1982
15
63
2.40
2.47
2.3
2.1
36.53
36.86
%
0.03
15
63
916
8789
1.32
2.44
5.4
4.9
2.76
2.78
mmol/l
0.33
849
8121
293
2502
1.24
2.43
4.2
3.8
—
—
—
0
0
277
2351
1.24
2.43
4.0
3.0
0.29
0.45
e6/l
1.04
223
1786
169
1352
1.30
2.42
3.4
2.3
12.11
13.24
umol/l
1.47
159
1261
943
9091
1.35
2.39
17.2
13.1
—
—
—
0
0
271
2299
1.24
2.38
4.0
3.0
—
—
—
0
0
91
666
1.40
2.34
3.7
2.8
9.78
10.77
g/l
1.66
83
608
269
2285
1.24
2.33
5.6
4.0
0.00
0.01
estimate
1.08
94
794
147
1160
1.31
2.33
3.7
2.3
21.39
22.94
%
0.83
129
992
276
2354
1.23
2.30
4.4
3.3
—
—
—
0
0
18
85
2.14
2.29
1.2
1.6
—
—
—
0
0
99
738
1.38
2.29
4.8
3.8
—
—
—
0
0
150
1190
1.30
2.29
1.5
1.3
776.41
532.11
titre
0.51
39
261
235
1971
1.25
2.28
1.9
1.7
1.12
1.10
mg/l
0.04
181
1504
309
2670
1.22
2.27
3.2
3.0
—
—
—
0
0
93
687
1.39
2.27
9.2
8.6
—
—
—
0
0
125
971
1.33
2.22
1.5
1.3
—
—
—
0
0
27
150
1.82
2.21
6.3
2.7
—
—
—
0
0
5
9
5.58
2.21
1.0
1.3
—
—
—
0
0
329
2871
1.21
2.18
4.2
3.2
29.03
31.75
u/l
1.20
316
2728
900
8644
1.28
2.16
5.0
4.4
4.67
4.70
mmol/l
0.44
836
8032
90
668
1.38
2.15
4.3
3.0
176.99
198.57
ng/l
0.27
85
610
62
431
1.47
2.12
2.8
2.4
—
—
—
0
0
8
25
3.22
2.09
1.8
1.2
2.25
4.08
mmol/l
—
8
20
101
769
1.35
2.06
4.5
3.5
2.29
1.95
mmol/l
0.48
86
634
43
280
1.56
2.00
3.0
1.5
0.21
0.24
g/l
0.99
38
264
894
8597
1.26
2.00
4.9
4.3
1.47
1.48
mmol/l
0.43
827
7941
153
1240
1.27
1.99
3.6
2.3
2.29
2.34
g/l
0.59
145
1148
81
601
1.38
1.96
4.1
2.8
4.69
5.26
e9/l
0.32
68
498
151
1225
1.27
1.95
1.3
1.2
—
—
—
0
0
39
250
1.58
1.95
2.6
3.3
—
—
—
0
0
145
1171
1.28
1.95
1.7
1.6
—
—
—
0
0
866
8305
1.24
1.94
4.4
3.9
1.32
1.29
mmol/l
0.72
795
7622
105
814
1.32
1.91
2.3
2.3
0.23
0.22
g/l
1.69
98
770
228
1943
1.22
1.90
4.9
3.6
—
—
—
0
0
74
545
1.38
1.88
5.9
5.6
—
—
—
0
0
241
2075
1.21
1.81
2.2
2.3
—
—
—
0
0
263
2289
1.20
1.76
4.9
4.2
—
—
—
0
0
119
951
1.28
1.75
2.1
1.5
—
—
—
0
0
12
54
2.24
1.74
4.2
7.1
—
—
—
0
0
7
24
2.93
1.72
2.4
1.4
—
—
—
0
0
13
61
2.15
1.72
1.2
1.1
—
—
—
0
0
49
341
1.46
1.71
1.4
1.2
1.04
1.20
u/ml
—
5
26
280
2458
1.19
1.70
3.4
2.9
1272.13
1241.33
ng/l
0.05
244
2086
7
25
2.81
1.65
2.1
1.4
—
—
—
0
0
250
2179
1.19
1.64
5.1
3.7
94.92
91.57
%
1.27
243
2124
11
49
2.26
1.64
1.5
1.4
—
—
—
0
0
271
2386
1.18
1.58
1.8
1.7
1.46
1.39
mmol/l
0.59
231
2007
81
624
1.32
1.58
1.2
1.2
89.72
137.05
iu/ml
1.28
32
257
198
1697
1.21
1.56
1.7
1.5
2.16
2.44
g/l
1.40
114
1039
85
665
1.30
1.49
6.2
4.0
0.57
0.61
%
0.06
28
221
37
251
1.49
1.49
1.5
1.3
235.16
249.75
miu/ml
0.08
15
116
9
37
2.44
1.48
2.4
2.1
96.33
65.31
ug/l
—
9
37
7
28
2.51
1.45
2.3
2.0
—
—
—
0
0
6
22
2.74
1.43
1.2
1.1
—
16.80
%
—
0
5
224
1958
1.18
1.42
1.3
1.3
0.73
1.44
u/ml
1.72
57
537
102
823
1.27
1.42
4.9
4.1
—
—
—
0
0
214
1866
1.18
1.40
1.7
1.7
37778221.94
23902237.80
pmol/l
0.14
180
1548
167
1424
1.21
1.40
2.9
2.6
1.07
1.09
e6/l
0.02
105
807
89
709
1.28
1.38
4.3
3.3
—
—
—
0
0
91
727
1.28
1.38
6.2
4.1
0.71
1.01
%
0.69
35
261
5
17
2.95
1.36
2.0
1.2
7.40
32.17
%
—
5
12
14
75
1.88
1.34
1.1
1.1
—
—
—
0
0
43
308
1.41
1.34
1.8
1.9
20.71
21.41
s
0.63
38
276
615
5807
1.14
1.34
3.3
3.1
46.23
49.19
u/l
0.40
575
5423
69
534
1.31
1.33
2.5
1.7
1.00
1.46
g/l
2.21
60
490
156
1329
1.20
1.32
3.4
2.8
2.05
2.36
e6/l
0.24
91
713
64
491
1.32
1.32
1.5
1.2
—
—
—
0
0
20
121
1.67
1.31
1.3
1.3
0.64
0.63
nmol/l
0.05
20
114
6
24
2.51
1.30
1.0
1.3
—
—
—
0
0
81
644
1.28
1.29
6.5
4.2
0.00
0.61
%
0.66
23
176
6
25
2.41
1.24
1.8
1.6
132.33
95.04
nmol/24h
—
6
25
16
93
1.73
1.21
2.2
2.7
—
—
—
0
0
40
290
1.39
1.19
4.3
3.3
0.20
0.25
g/l
0.27
23
115
6
26
2.31
1.19
1.0
1.4
—
—
—
0
0
6
26
2.31
1.19
1.3
4.2
63.17
50.94
%
—
6
26
49
368
1.35
1.18
1.3
1.9
1.46
1.49
g/l
0.07
42
322
230
2047
1.16
1.17
1.5
1.5
21.26
21.16
nmol/l
0.03
204
1754
19
118
1.62
1.15
4.1
2.0
33.16
32.38
pg
0.32
19
118
5
20
2.51
1.15
1.2
1.1
—
—
—
0
0
65
511
1.29
1.15
11.6
9.9
1.24
1.37
%
0.82
65
506
35
252
1.40
1.09
1.4
1.2
—
1121.00
—
0
10
182
1601
1.17
1.09
2.8
2.9
2.45
2.45
mmol/l
0.03
156
1411
86
706
1.24
1.08
5.7
3.7
1.23
1.23
mmol/l
0.04
75
618
69
552
1.27
1.08
1.2
1.2
—
—
—
0
0
64
508
1.28
1.06
11.7
10.0
0.60
0.69
%
1.13
64
503
18
113
1.60
1.06
1.1
1.3
—
—
—
0
0
22
147
1.51
1.01
1.2
1.2
—
—
—
0
0
357
3303
1.12
1.01
4.0
3.5
29.16
48.05
ng/l
0.97
230
2256
83
685
1.23
1.00
1.9
1.6
—
—
—
0
0
83
685
1.23
1.00
6.5
4.2
0.07
0.14
%
0.54
27
218
26
181
1.45
0.99
2.7
2.2
124.39
128.76
g/l
0.39
18
140
262
2382
1.13
0.98
5.0
4.9
1.99
2.44
ug/l
1.01
233
2127
167
1473
1.16
0.97
1.3
1.3
14.97
12.02
u/ml
0.21
78
555
162
1428
1.16
0.95
2.0
1.7
—
—
—
0
0
14
85
1.66
0.94
1.1
1.2
—
—
—
0
0
23
158
1.47
0.94
3.2
2.6
—
—
—
0
0
6
28
2.15
0.91
1.0
1.1
1907.83
1618.32
miu/ml
—
6
28
34
253
1.36
0.91
2.0
2.1
973.17
2864.47
u/l
0.73
11
90
43
332
1.31
0.90
3.0
3.3
2823.41
1300.01
u/ml
0.22
34
284
11
63
1.75
0.90
2.5
1.4
93.73
77.76
umol/l
0.57
11
63
67
550
1.23
0.87
2.2
2.2
14.93
12.93
nmol/l
1.13
61
491
8
43
1.87
0.87
1.3
1.3
140.50
145.54
nmol/l
—
8
43
25
178
1.41
0.86
5.2
4.2
2.76
2.69
mmol/l
0.03
19
121
205
1854
1.13
0.84
5.5
4.0
1.02
1.02
kg/l
0.23
30
259
6
31
1.94
0.84
2.2
3.4
—
—
—
0
0
21
146
1.45
0.83
1.5
1.4
—
—
—
0
0
120
1047
1.16
0.82
2.1
2.2
127.93
130.33
ug/g
0.02
99
830
8
46
1.74
0.82
1.1
1.5
200.71
176.08
pmol/l
—
8
46
16
105
1.53
0.82
1.9
1.2
—
57.11
—
0
7
82
693
1.20
0.82
3.6
2.9
66.48
67.05
g/l
0.30
73
635
14
89
1.58
0.81
3.9
4.7
44.67
52.30
u/ml
—
6
28
16
106
1.52
0.79
1.2
1.3
—
—
nmol/l
—
0
0
41
322
1.28
0.78
5.1
4.3
—
—
—
0
0
12
74
1.63
0.78
1.1
1.2
—
—
—
0
0
103
893
1.17
0.77
4.3
4.0
13.54
27.18
ug/l
0.55
86
736
10
59
1.70
0.76
1.0
1.0
—
—
—
0
0
9
53
1.70
0.75
1.1
1.2
—
—
—
0
0
14
91
1.55
0.75
1.1
1.7
—
—
—
0
0
72
607
1.20
0.75
1.7
1.4
—
—
—
0
0
93
805
1.17
0.72
2.8
2.2
29.86
35.47
u/l
0.92
81
679
13
84
1.55
0.72
1.2
1.1
—
—
—
0
0
24
177
1.36
0.71
4.8
3.7
—
—
—
0
0
14
93
1.51
0.69
2.1
1.7
—
—
—
0
0
47
383
1.24
0.69
1.1
1.1
—
—
—
0
0
12
77
1.56
0.68
1.0
1.3
—
—
—
0
0
7
42
1.67
0.68
2.6
3.0
311.57
1144.14
u/ml
—
7
42
20
144
1.40
0.68
2.1
1.3
118.29
109.59
u/ml
—
7
30
18
127
1.42
0.68
1.6
3.3
0.97
1.26
%
0.26
18
116
19
136
1.40
0.67
1.7
1.4
—
—
—
0
0
18
128
1.41
0.66
1.2
1.2
—
—
—
0
0
19
137
1.39
0.65
1.2
1.2
1.71
7.11
u/ml
—
7
54
27
208
1.31
0.62
1.6
1.8
44.33
40.79
nmol/l
0.39
27
198
6
102
0.59
0.62
1.0
1.3
—
—
—
0
0
30
235
1.28
0.62
2.2
1.8
4.22
4.90
iu/l
0.19
12
78
5
30
1.67
0.61
1.0
1.2
50.60
36.50
g/l
—
5
18
106
941
1.14
0.61
1.7
1.6
—
—
—
0
0
43
353
1.23
0.61
2.5
2.0
2.37
1.94
ug/l
0.10
36
319
9
137
0.65
0.61
1.3
1.6
—
—
—
0
0
13
88
1.48
0.60
1.3
1.6
—
—
—
0
0
30
236
1.28
0.60
1.4
1.3
—
—
—
0
0
79
688
1.16
0.59
1.2
1.2
—
—
—
0
0
248
2314
1.09
0.59
1.4
1.4
—
—
—
0
0
31
246
1.27
0.58
1.8
2.2
10.42
11.93
mg/l
0.65
31
227
27
211
1.29
0.57
1.2
1.3
9.00
11.75
u/l
0.52
20
167
8
54
1.49
0.57
5.2
1.6
—
—
—
0
0
24
185
1.30
0.56
2.9
1.7
—
—
—
0
0
38
312
1.23
0.55
1.7
1.6
—
—
—
0
0
19
142
1.34
0.54
1.0
1.0
—
—
—
0
0
79
694
1.15
0.54
2.5
2.4
7.43
7.26
ug/l
0.03
67
612
17
125
1.37
0.54
5.2
2.2
—
—
—
0
0
25
315
0.79
0.52
1.0
1.1
—
—
—
0
0
12
83
1.45
0.52
2.0
2.6
—
—
—
0
0
9
65
1.39
0.50
1.2
1.1
—
—
—
0
0
21
269
0.78
0.50
14.4
9.6
—
—
—
0
0
6
41
1.47
0.50
1.8
1.7
1.73
6.31
nmol/l
—
6
32
47
399
1.19
0.50
1.2
1.3
26.75
30.06
iu/l
0.28
38
335
64
558
1.16
0.50
3.3
2.9
—
—
—
0
0
64
558
1.16
0.50
1.3
1.3
36.44
45.55
au/ml
—
5
37
19
145
1.32
0.49
1.0
1.1
—
—
—
0
0
7
45
1.56
0.49
1.0
1.0
—
—
—
0
0
13
93
1.40
0.48
2.5
1.1
—
—
—
0
0
97
873
1.12
0.48
1.4
1.5
—
—
—
0
0
70
620
1.14
0.45
2.4
2.4
15.47
24.43
au/ml
—
7
51
75
840
0.88
0.45
1.2
1.4
—
—
—
0
0
10
69
1.45
0.44
2.5
3.6
12.43
10.87
%
—
10
69
66
585
1.14
0.43
3.2
2.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
7.5
—
—
—
0
0
17
132
1.29
0.40
1.1
1.2
—
—
—
0
0
12
88
1.37
0.40
9.6
2.4
0.40
1.44
g/24h
—
6
44
13
171
0.76
0.39
1.5
1.3
—
—
—
0
0
14
106
1.33
0.39
2.1
1.8
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
11
148
0.74
0.39
1.1
1.1
0.66
2.86
u/ml
—
5
74
11
80
1.38
0.38
1.5
1.3
44327.83
119165.77
e6/l
—
6
44
20
161
1.25
0.37
2.1
1.4
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
83.33
—
0
9
11
81
1.36
0.36
1.2
1.3
—
—
—
0
0
19
153
1.25
0.35
1.5
1.3
57.83
62.09
mmol/l
0.15
12
129
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
62
559
1.12
0.33
5.2
3.5
7.38
7.41
ph
1.07
12
70
43
486
0.88
0.32
2.0
1.8
—
—
—
0
0
6
47
1.28
0.32
1.0
1.2
—
—
—
0
0
33
289
1.15
0.28
1.8
1.5
495.74
304.80
mu/l
0.88
27
264
13
103
1.27
0.28
3.8
2.5
—
—
—
0
0
18
149
1.21
0.28
1.2
1.2
—
—
—
0
0
19
160
1.19
0.25
1.5
1.2
310.90
271.47
u/ml
—
10
95
26
226
1.15
0.25
1.4
1.2
—
—
—
0
0
13
105
1.24
0.25
1.8
1.4
30.79
32.50
g/l
0.28
13
92
13
106
1.23
0.23
3.8
2.5
3.92
4.06
mmol/l
0.80
13
106
13
106
1.23
0.23
3.8
2.5
106.46
105.34
mmol/l
0.60
13
106
16
189
0.84
0.22
3.3
3.3
—
—
—
0
0
5
41
1.22
0.22
1.2
1.4
—
—
—
0
0
17
144
1.18
0.22
1.1
1.3
—
—
—
0
0
26
229
1.14
0.21
1.7
1.2
9.30
2.58
u/ml
—
6
26
5
42
1.19
0.21
1.2
1.0
—
7.34
—
0
6
0
11
0.00
0.21
0.0
13.1
—
0.25
—
0
11
15
126
1.19
0.21
4.1
3.1
—
—
—
0
0
5
43
1.16
0.21
1.2
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
0.28
—
0
14
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
25
221
1.13
0.20
5.4
4.7
—
—
—
0
0
6
49
1.23
0.20
1.7
2.0
—
51.34
—
0
5
6
51
1.18
0.19
1.0
1.1
—
—
—
0
0
20
175
1.15
0.18
3.9
2.4
15.34
16.03
%
0.37
14
91
11
132
0.83
0.18
1.5
1.4
—
—
—
0
0
26
233
1.12
0.17
1.7
1.2
47.74
9.38
u/ml
—
5
41
11
91
1.21
0.17
1.5
1.1
—
—
—
0
0
12
142
0.84
0.17
1.8
1.5
—
—
—
0
0
30
272
1.11
0.17
1.4
1.2
—
—
—
0
0
25
278
0.90
0.17
1.4
1.3
—
—
—
0
0
25
277
0.90
0.16
1.4
1.3
—
—
—
0
0
23
256
0.90
0.16
1.4
1.3
—
—
—
0
0
8
72
1.11
0.16
1.5
1.4
—
—
—
0
0
6
77
0.78
0.15
1.2
3.0
58.33
54.98
%
—
6
69
10
83
1.21
0.15
1.7
1.4
—
—
—
0
0
22
197
1.12
0.15
9.6
4.1
—
—
—
0
0
21
234
0.90
0.15
1.0
1.1
—
—
—
0
0
86
821
1.05
0.15
1.5
1.4
—
—
—
0
0
25
275
0.91
0.14
1.4
1.3
—
—
—
0
0
7
86
0.81
0.14
1.1
1.2
—
—
—
0
0
25
274
0.91
0.14
1.4
1.3
—
—
—
0
0
15
132
1.14
0.13
1.7
1.8
0.48
0.87
g/l
—
10
97
312
3174
0.98
0.12
2.9
2.8
—
—
—
0
0
10
85
1.18
0.12
8.2
2.3
—
—
—
0
0
11
126
0.87
0.11
1.4
1.4
—
—
—
0
0
11
126
0.87
0.11
1.4
1.4
—
—
—
0
0
40
424
0.94
0.11
5.4
3.6
—
—
—
0
0
13
115
1.13
0.10
4.6
2.4
—
—
—
0
0
5
44
1.14
0.10
2.0
2.5
—
—
—
0
0
5
46
1.09
0.09
2.0
1.2
—
—
—
0
0
15
136
1.10
0.08
1.1
1.1
—
—
—
0
0
6
57
1.05
0.08
1.2
1.4
1.67
1.57
g/l
—
6
57
7
82
0.85
0.07
2.4
2.5
—
—
—
0
0
7
84
0.83
0.07
2.3
1.6
—
—
—
0
0
7
84
0.83
0.07
5.7
3.4
—
—
—
0
0
54
521
1.04
0.07
1.3
1.5
—
—
—
0
0
8
91
0.88
0.06
2.0
3.8
—
—
—
0
0
17
158
1.08
0.06
1.2
1.6
—
—
—
0
0
14
151
0.93
0.05
1.1
1.2
249.95
25.77
u/l
—
8
135
17
181
0.94
0.05
1.5
1.6
—
—
—
0
0
140
1383
1.01
0.04
2.9
3.0
0.71
0.75
ug/l
0.16
88
907
12
129
0.93
0.03
1.1
1.0
1.40
1.48
u/ml
—
6
55
21
219
0.96
0.03
3.0
2.4
—
—
—
0
0
20
208
0.96
0.02
1.2
1.3
—
—
—
0
0
27
262
1.03
0.02
1.1
1.2
—
—
—
0
0
32
328
0.97
0.01
2.5
2.6
—
—
—
0
0
11
104
1.06
0.01
1.8
1.2
—
—
—
0
0
26
254
1.02
0.00
6.0
3.7
3.81
3.87
mmol/l
0.25
26
249
14
136
1.03
0.00
1.1
1.1
—
—
—
0
0
41
414
0.99
0.00
6.2
3.5
—
—
—
0
0
25
251
1.00
0.00
1.8
1.5
285.79
283.77
ug/g
0.02
18
147
11
113
0.97
0.00
1.1
1.4
—
—
—
0
0
19
187
1.02
0.00
3.0
3.8
23.08
26.02
mg/l
0.15
13
116
37
373
0.99
0.00
2.2
1.9
—
—
—
0
0
20
205
0.98
0.00
2.8
2.2
340.26
90.99
ug/min
0.50
11
128
13
135
0.96
0.00
1.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
0.00
2.1
1.6
1.00
1.03
g/l
—
7
69
0
5
0.00
0.00
0.0
1.2
—
100.00
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
7
72
0.97
-0.00
1.7
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
8
81
0.99
-0.00
1.1
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
6
59
1.02
-0.00
1.2
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.0
—
—
—
0
0
8
80
1.00
-0.00
1.9
1.3
5.26
6.84
mmol/l
—
8
73
0
7
0.00
-0.00
0.0
4.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
55
0.91
-0.00
1.4
1.8
3.00
2.89
u/field
—
5
41
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_BENIGN_SKIN_LOWERLIMB – Benign neoplasm: Skin of lower limb, including hip

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).