Otorrhagia

H8_OTORRHAGIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H92.2
  • Cause of death: ICD-10 H92.2

2 out of 7 registries used, show all original rules.

224

4. Check minimum number of events

None

224

5. Include endpoints

None

224

6. Filter based on genotype QC (FinnGen only)

224

Control definitions (FinnGen only)

Control exclude
H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H92
Name in latin
Otorrhagia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1851 828 1014
Only index persons 1598 720 878
Unadjusted period prevalence (%)
Whole population 0.03 0.02 0.03
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 56.80 63.46 51.22
Only index persons 59.29 66.15 53.66

-FinnGen-

Key figures

All Female Male
Number of individuals 224 103 121
Unadjusted period prevalence (%) 0.04 0.04 0.05
Median age at first event (years) 63.43 63.89 63.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
200
Matched controls
1999
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H92.2
ICD-10 Finland
Otorrhagia
+∞
285.1
200
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
64.3
32.6
37
7
UDC00
NOMESCO Finland
Ear microscopy
9.8
18.8
39
48
DFF00
NOMESCO Finland
Pure tone audiometry
11.9
15.3
28
27
H92.0
ICD-10 Finland
Otalgia
9.2
11.7
24
29
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.5
11.6
43
114
I48
ICD-10 Finland
Atrial fibrillation and flutter
3.2
11.2
70
287
H05
ICPC
Bleeding ear
63.4
10.7
12
*
R04.0
ICD-10 Finland
Epistaxis
4.9
9.2
30
69
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.0
9.1
60
249
H91.9
ICD-10 Finland
Hearing loss, unspecified
13.6
8.5
14
11
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
8.5
71
340
R4110
NOMESCO Finland
Physiotherapy
2.7
8.4
71
343
ZXA05
NOMESCO Finland
Left side
2.7
8.4
66
304
AA1AD
NOMESCO Finland
CT of head and brain
2.8
8.4
61
267
ZXA10
NOMESCO Finland
Bilateral
3.1
8.4
50
194
B01AA03
ATC
warfarin; systemic
2.8
8.3
63
282
N02BE01
ATC
paracetamol; systemic, rectal
3.1
8.2
173
1353
WX110
NOMESCO Finland
Local anesthesy
2.5
8.1
144
1016
H65.3
ICD-10 Finland
Chronic mucoid otitis media
8.3
8.1
17
22
C03CA01
ATC
furosemide; systemic
2.4
7.5
77
408
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
7.5
94
549
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
8.9
7.5
15
18
N02AX02
ATC
tramadol; systemic, rectal
2.3
7.4
96
569
H02AB06
ATC
prednisolone; systemic
2.3
7.3
100
610
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
4.0
7.0
28
79
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
7.0
69
355
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
7.0
52
229
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
6.8
96
586
L17
ICPC
Foot/toe symptom/complaint
2.5
6.8
60
292
C07AB07
ATC
bisoprolol; oral
2.2
6.7
104
661
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
6.5
36
132
D11
ICPC
Diarrhoea
3.6
6.4
28
86
S01.3
ICD-10 Finland
Open wound of ear
18.7
6.3
9
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
6.3
84
493
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
+∞
6.3
6
*
I50.9
ICD-10 Finland
Heart failure, unspecified
2.8
6.2
41
166
Z97.4
ICD-10 Finland
Presence of external hearing-aid
13.1
6.1
10
8
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.1
6.1
18
38
TFP20
NOMESCO Finland
Cardiodefibrillation
3.6
6.1
26
79

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
63
236
3.32
13.46
36.3
23.3
1.4
1.3
inr
—
5
29
87
442
2.58
10.25
2.7
2.2
2.7
3.2
mg/l
1.16
80
381
49
188
3.06
9.83
12.0
9.2
—
—
—
0
0
117
715
2.33
8.85
16.0
9.3
1.4
1.3
inr
0.54
28
210
127
811
2.31
8.57
13.0
6.8
1.2
1.2
mmol/l
0.51
118
744
27
77
3.85
8.55
3.1
2.6
22.7
22.0
s
0.26
22
71
123
786
2.25
8.15
7.8
5.1
35.3
35.5
g/l
0.14
115
749
41
161
2.89
7.81
2.5
2.8
71.0
68.2
e9/l
0.17
31
117
56
262
2.52
7.56
2.4
1.9
—
—
—
0
0
137
936
2.19
7.43
7.8
6.0
0.2
0.2
e9/l
0.29
117
805
51
230
2.58
7.42
2.7
2.7
1.9
1.7
%
0.62
45
209
134
908
2.18
7.42
7.4
5.8
0.0
0.0
e9/l
0.11
113
771
133
903
2.16
7.27
7.1
5.8
0.6
0.6
e9/l
1.69
113
763
91
534
2.19
7.24
2.3
2.1
178.9
487.3
u/l
0.99
84
505
132
896
2.15
7.19
14.4
7.4
1.2
1.2
mmol/l
0.73
116
766
108
681
2.13
7.11
2.4
2.0
91.7
90.9
pmol/l
0.06
60
339
135
933
2.12
6.91
7.5
5.9
1.9
2.1
e9/l
0.28
113
811
126
859
2.07
6.57
7.5
6.2
9.1
8.6
%
0.86
119
809
65
345
2.25
6.52
5.5
3.5
151.4
299.5
ng/l
0.60
53
284
112
734
2.05
6.48
4.5
2.7
193.6
126.7
ug/l
0.84
106
678
106
682
2.05
6.44
5.9
3.9
27.0
47.6
ng/l
1.60
77
498
52
252
2.39
6.43
12.6
6.7
1.2
1.1
mmol/l
0.43
47
230
146
1065
2.07
6.16
12.0
9.3
4.1
4.2
e9/l
0.18
124
915
98
622
2.02
6.10
7.6
5.6
—
—
—
0
0
124
856
2.00
6.08
7.4
5.8
2.6
2.8
%
0.33
117
801
121
831
1.99
5.99
7.4
5.9
0.6
0.7
%
0.33
114
775
88
541
2.03
5.96
5.1
4.3
—
—
—
0
0
125
873
1.98
5.85
7.3
5.8
56.7
57.8
%
0.34
116
821
144
1060
2.00
5.74
9.9
5.5
6.9
6.7
mmol/l
0.45
137
982
43
201
2.41
5.73
2.0
1.7
—
—
—
0
0
125
885
1.93
5.49
7.5
6.0
27.1
27.4
%
0.08
117
829
87
547
1.97
5.43
3.3
2.4
57.7
56.2
u/l
0.18
81
509
70
411
2.02
5.28
3.8
4.0
—
—
—
0
0
80
494
1.96
5.23
10.4
6.1
—
—
—
0
0
44
219
2.26
5.06
10.0
6.0
—
—
—
0
0
75
459
1.95
4.99
3.7
2.8
363.4
8188.0
umol/l
2.36
66
392
71
427
1.97
4.97
1.8
1.6
20.7
20.8
nmol/l
0.02
64
358
67
399
1.97
4.81
2.9
1.8
1.2
1.3
mg/l
0.26
51
308
43
217
2.21
4.77
1.3
1.3
—
—
—
0
0
172
1390
2.02
4.75
10.4
7.3
82.3
81.7
u/l
0.07
166
1307
86
560
1.87
4.70
3.9
2.4
—
—
—
0
0
86
564
1.85
4.57
8.3
3.7
7.4
7.4
ph
—
9
110
42
219
2.13
4.29
11.8
8.1
1.3
1.0
mmol/l
0.27
35
178
155
1234
1.83
4.18
4.6
3.8
—
—
—
0
0
14
42
3.49
4.11
2.0
1.2
—
—
—
0
0
46
257
1.99
3.89
13.5
7.3
103.5
104.0
mmol/l
0.33
46
249
160
1300
1.81
3.87
4.7
3.8
15.0
14.9
pmol/l
0.20
150
1161
6
5
12.27
3.78
2.7
4.6
369.0
56.6
nmol/l
—
6
5
26
117
2.38
3.75
1.2
1.2
—
—
—
0
0
53
315
1.89
3.74
1.9
1.8
1106.1
1200.7
nmol/l
0.34
41
241
202
1787
2.33
3.62
26.6
14.8
25.3
26.0
mg/l
0.10
171
1410
77
519
1.74
3.59
4.5
3.3
7.3
7.7
mmol/l
0.38
66
434
187
1610
1.98
3.58
4.6
3.9
1.2
1.3
mmol/l
0.59
169
1470
11
31
3.68
3.53
1.5
1.8
—
—
—
0
0
6
6
10.23
3.51
2.8
1.8
—
—
—
0
0
184
1580
1.92
3.49
5.6
4.6
2.0
1.9
mu/l
0.23
174
1433
12
37
3.37
3.39
3.8
2.1
—
—
—
0
0
17
65
2.75
3.39
3.1
1.8
—
—
—
0
0
12
38
3.28
3.26
2.9
1.6
—
—
—
0
0
80
559
1.67
3.21
4.1
3.2
0.2
0.4
e6/l
1.81
58
413
58
372
1.75
3.17
1.5
1.3
4.1
1.3
u/ml
0.48
12
104
177
1520
1.78
3.11
34.7
18.9
330.5
333.0
g/l
2.80
177
1512
20
87
2.43
3.11
16.5
11.4
—
—
—
0
0
193
1703
1.96
3.09
5.8
4.9
2.4
2.7
mmol/l
4.91
176
1558
189
1657
1.90
3.08
4.9
4.4
6.0
6.0
mmol/l
0.04
175
1504
156
1298
1.66
3.05
5.0
4.1
13.2
11.9
mm/h
0.46
145
1191
86
619
1.63
3.05
4.9
3.2
81.6
45.6
e6/l
0.26
66
472
207
1881
2.32
2.94
14.9
10.2
27.2
25.7
u/l
0.42
202
1812
85
615
1.62
2.93
4.2
3.4
2.3
2.4
mmol/l
0.02
75
556
89
653
1.60
2.88
2.3
2.0
—
—
—
0
0
25
125
2.13
2.84
8.4
4.5
—
—
—
0
0
69
477
1.65
2.84
3.9
3.3
76.8
70.1
mg/l
0.05
46
329
188
1659
1.83
2.82
5.2
4.3
1.3
1.4
mmol/l
2.65
172
1519
27
141
2.04
2.74
3.9
4.0
—
—
—
0
0
11
37
3.07
2.73
12.0
6.0
71.8
69.7
%
0.12
11
37
188
1664
1.81
2.72
5.3
4.4
4.1
4.6
mmol/l
8.15
173
1535
71
507
1.59
2.53
4.7
4.0
16.4
11.5
mg/mmol
0.20
47
326
53
352
1.66
2.52
3.0
3.2
2.5
2.5
mmol/l
0.17
48
316
143
1193
1.55
2.51
6.1
4.3
—
—
—
0
0
11
39
2.91
2.51
2.4
1.7
180.5
298.9
u/ml
—
6
19
13
51
2.64
2.49
12.8
7.3
—
—
—
0
0
18
83
2.27
2.48
2.7
2.3
—
—
—
0
0
73
527
1.57
2.47
4.0
3.2
—
—
—
0
0
24
125
2.03
2.47
3.0
2.2
—
—
—
0
0
13
52
2.59
2.40
2.0
1.7
—
—
—
0
0
202
1848
1.95
2.34
24.3
13.2
—
—
—
0
0
34
204
1.79
2.31
2.3
1.4
—
—
—
0
0
212
1975
2.37
2.31
38.3
21.1
4.4
4.5
e12/l
3.16
207
1901
36
220
1.76
2.30
1.4
1.4
354.3
517.9
titre
—
7
58
74
545
1.53
2.27
4.4
3.1
—
—
—
0
0
14
60
2.42
2.27
2.1
1.6
—
—
—
0
0
32
190
1.80
2.25
2.5
1.6
—
—
—
0
0
10
36
2.86
2.23
1.6
1.4
—
—
—
0
0
90
696
1.49
2.18
6.3
3.7
36.2
52.2
e6/l
0.51
67
500
6
14
4.37
2.16
2.2
2.7
—
—
—
0
0
8
25
3.28
2.11
1.3
1.3
—
—
—
0
0
9
31
2.98
2.09
1.6
1.8
—
—
—
0
0
9
31
2.98
2.09
1.6
1.8
—
—
—
0
0
9
31
2.98
2.09
1.6
1.8
—
—
—
0
0
9
31
2.98
2.09
1.6
1.8
—
—
—
0
0
107
862
1.46
2.08
11.8
9.5
0.0
0.0
e9/l
0.47
87
690
22
119
1.94
2.06
1.6
1.5
—
—
—
0
0
107
864
1.46
2.05
4.4
3.9
0.0
0.0
estimate
0.00
13
168
180
1613
1.59
2.03
30.2
15.9
38.5
39.8
%
1.01
133
1193
178
1592
1.58
2.01
7.2
5.7
40.4
40.1
mmol/mol
0.13
166
1484
16
78
2.13
1.96
10.9
4.6
—
—
—
0
0
8
27
3.03
1.95
1.0
1.2
—
—
—
0
0
23
129
1.87
1.94
11.0
5.2
24.2
24.1
mmol/l
0.05
23
117
171
1524
1.52
1.88
32.2
18.0
14.0
13.7
%
1.87
166
1496
44
301
1.57
1.85
2.4
1.8
—
—
—
0
0
6
18
3.39
1.76
2.0
1.3
—
—
—
0
0
57
419
1.48
1.72
3.5
2.5
5.2
4.5
e6/l
0.27
44
377
5
13
3.91
1.72
1.0
1.4
—
—
—
0
0
5
13
3.91
1.72
1.6
2.2
—
—
—
0
0
107
884
1.40
1.72
4.7
4.0
0.0
0.0
estimate
0.00
14
168
55
405
1.47
1.65
4.4
2.6
508.8
563.7
mosm/kgh2o
1.01
43
348
105
871
1.39
1.62
6.3
5.3
0.0
0.0
estimate
0.00
14
170
50
364
1.48
1.58
1.6
1.4
2.6
2.4
g/l
0.22
25
229
48
348
1.48
1.55
1.7
1.9
176316306.6
444.4
pmol/l
0.49
38
301
32
213
1.59
1.51
1.3
1.3
—
—
—
0
0
5
16
3.17
1.44
1.0
1.4
6.4
3.7
mg/l
—
5
16
46
607
0.70
1.39
3.2
2.9
—
—
—
0
0
7
148
0.46
1.37
1.3
1.4
—
—
—
0
0
6
23
2.65
1.37
1.5
3.0
—
—
—
0
0
9
43
2.14
1.32
5.7
1.6
—
—
—
0
0
12
62
1.99
1.30
1.1
1.1
—
—
—
0
0
24
155
1.61
1.29
4.6
4.8
0.0
0.1
%
—
8
45
17
100
1.76
1.27
4.8
3.8
—
—
—
0
0
24
156
1.60
1.26
1.7
1.5
—
—
—
0
0
33
232
1.50
1.24
2.5
1.6
—
—
—
0
0
18
109
1.71
1.23
5.4
7.2
—
—
—
0
0
5
19
2.67
1.22
1.2
2.3
—
597.6
—
0
8
5
19
2.67
1.22
1.0
1.2
—
—
—
0
0
5
19
2.67
1.22
1.2
1.2
—
—
—
0
0
5
19
2.67
1.22
3.0
2.7
4.5
12.1
nmol/l
—
5
19
5
19
2.67
1.22
1.0
1.1
—
—
—
0
0
25
166
1.57
1.21
4.6
4.7
0.8
0.7
%
—
8
53
23
150
1.59
1.20
3.5
4.5
0.2
0.5
%
—
5
35
80
661
1.33
1.20
4.2
4.7
2.0
2.6
ug/l
0.49
71
585
0
33
0.00
1.17
0.0
1.1
—
0.6
—
0
26
0
34
0.00
1.17
0.0
1.1
—
7.7
—
0
28
8
39
2.09
1.16
1.6
1.6
—
—
—
0
0
5
20
2.53
1.15
1.4
1.2
—
—
—
0
0
5
20
2.53
1.15
2.4
1.3
—
—
—
0
0
52
407
1.36
1.10
4.8
5.0
—
—
—
0
0
7
32
2.22
1.09
6.0
3.4
—
—
—
0
0
21
138
1.58
1.07
3.3
2.4
10.8
9.7
g/l
0.41
21
125
18
114
1.63
1.06
2.2
2.3
—
6.8
—
0
6
5
22
2.30
1.04
4.6
2.2
—
—
—
0
0
5
22
2.30
1.04
6.6
8.8
11.5
11.9
%
—
5
22
12
69
1.78
0.98
9.9
2.8
3.9
4.0
mmol/l
0.34
12
62
0
30
0.00
0.98
0.0
4.4
—
6.4
—
0
24
9
50
1.83
0.98
1.0
1.2
—
—
—
0
0
6
28
2.17
0.92
6.2
2.8
—
—
—
0
0
11
63
1.78
0.92
4.3
3.5
—
—
—
0
0
6
30
2.03
0.87
6.7
1.3
—
—
—
0
0
8
46
1.77
0.83
5.0
1.3
—
—
—
0
0
19
131
1.49
0.81
4.7
4.3
—
—
—
0
0
10
58
1.76
0.81
10.1
11.0
—
—
—
0
0
58
483
1.27
0.80
1.3
1.4
—
—
—
0
0
21
150
1.44
0.76
5.3
4.8
0.0
0.0
%
—
6
40
5
26
1.94
0.71
2.2
3.3
—
—
—
0
0
5
26
1.94
0.71
1.0
1.8
19.4
20.6
ug/l
—
5
26
11
69
1.62
0.69
3.3
2.9
—
—
—
0
0
29
225
1.33
0.67
2.3
2.5
125.3
115.9
ug/g
0.07
22
178
5
28
1.80
0.66
1.4
1.1
—
—
—
0
0
58
496
1.23
0.64
7.4
3.9
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
16
115
1.42
0.58
1.4
1.6
1.2
1.1
g/l
0.29
16
106
8
54
1.50
0.58
5.3
1.3
—
—
—
0
0
13
91
1.45
0.54
1.1
1.2
148.0
432.9
u/ml
0.53
13
85
16
117
1.40
0.54
3.8
2.7
4.8
4.0
e9/l
0.37
11
95
18
135
1.36
0.53
4.2
2.7
—
—
—
0
0
54
476
1.18
0.44
4.5
4.2
0.0
0.0
estimate
0.00
14
162
8
58
1.39
0.42
5.3
1.3
—
—
—
0
0
17
132
1.31
0.41
1.6
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
8
60
1.35
0.40
5.3
1.3
—
—
—
0
0
8
60
1.35
0.40
5.3
1.3
—
—
—
0
0
8
60
1.35
0.40
5.3
1.3
—
—
—
0
0
20
160
1.27
0.40
1.8
1.7
—
—
—
0
0
5
35
1.44
0.39
1.4
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
4.8
—
—
—
0
0
15
116
1.31
0.38
1.3
1.1
179.1
139.2
iu/ml
—
7
43
19
153
1.26
0.37
1.4
1.3
—
—
—
0
0
13
102
1.29
0.30
1.2
1.2
—
—
—
0
0
12
147
0.81
0.24
6.0
3.6
—
—
—
0
0
5
41
1.22
0.22
1.6
2.5
—
—
—
0
0
29
259
1.14
0.21
1.5
1.3
1.6
15.6
u/ml
1.90
12
110
0
11
0.00
0.21
0.0
1.0
—
170.9
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
3.0
—
—
—
0
0
11
89
1.25
0.21
1.2
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
4.3
—
0
6
0
14
0.00
0.20
0.0
1.0
—
3.1
—
0
14
0
14
0.00
0.20
0.0
6.2
—
—
—
0
0
8
70
1.15
0.16
1.3
1.2
—
—
—
0
0
8
72
1.12
0.16
1.0
1.1
—
—
—
0
0
13
112
1.17
0.14
7.1
2.6
0.2
0.1
e6/l
0.37
13
105
46
487
0.93
0.13
4.3
3.4
—
—
—
0
0
5
60
0.83
0.08
1.6
2.0
—
—
—
0
0
15
159
0.94
0.03
1.3
1.5
—
—
—
0
0
11
102
1.08
0.03
1.3
1.3
—
—
—
0
0
39
399
0.97
0.02
2.5
2.8
0.7
0.8
ug/l
0.66
31
258
27
278
0.97
0.02
1.4
1.3
101.3
31.0
iu/ml
—
8
104
20
195
1.03
0.00
1.3
1.3
—
—
—
0
0
7
72
0.97
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
12.4
—
0
5
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
120.2
—
0
7
0
7
0.00
0.00
0.0
3.9
—
0.8
—
0
7
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
115.7
—
0
8
0
5
0.00
0.00
0.0
5.6
—
—
—
0
0
0
7
0.00
0.00
0.0
6.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
18.7
—
1.2
—
0
7
0
7
0.00
0.00
0.0
2.3
—
2406.4
—
0
7
6
62
0.97
0.00
5.5
4.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
14
140
1.00
0.00
2.1
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_OTORRHAGIA and mortality.

Females

Parameter HR [95% CI] p-value
H8_OTORRHAGIA 1.65 [1.23, 2.22] 0.001
Birth year 0.997 [0.99, 1.01] 0.45

During the follow-up period (1.1.1998 — 31.12.2019), 153 out of 677 females with H8_OTORRHAGIA died.

Males

Parameter HR [95% CI] p-value
H8_OTORRHAGIA 2.165 [1.52, 3.07] < 0.001
Birth year 0.987 [0.98, 1.0] 0.012

During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 847 males with H8_OTORRHAGIA died.

Mortality risk

Mortality risk for people of age

years, who have H8_OTORRHAGIA.

N-year risk Females Males
1 0.191% 0.416%
5 0.975% 2.488%
10 2.277% 5.739%
15 4.61% 10.897%
20 8.497% 17.972%

Relationships between endpoints

Index endpoint: H8_OTORRHAGIA – Otorrhagia

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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