No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
256 |
4. Check minimum number of eventsNone |
256 |
5. Include endpointsNone |
256 |
6. Filter based on genotype QC (FinnGen only) |
247 |
Control definitions (FinnGen only)
- Control exclude
- H8_OTHEREAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H92
- Name in latin
- Otorrhagia
Similar endpoints
↥List of similar endpoints to
Otorrhagia
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1851 | 828 | 1014 |
| Only index persons | 1598 | 720 | 878 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.02 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 56.80 | 63.46 | 51.22 |
| Only index persons | 59.29 | 66.15 | 53.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 247 | 114 | 133 |
| Unadjusted period prevalence (%) | 0.05 | 0.04 | 0.06 |
| Median age at first event (years) | 63.89 | 64.11 | 63.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 256
- Matched controls
- 2560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H92.2
ICD-10 Finland
Otorrhagia
+∞
307.7
256
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
39.6
80.6
51
16
UDC00
NOMESCO Finland
Ear microscopy
11.6
43.6
49
51
DFF00
NOMESCO Finland
Pure tone audiometry
12.0
36.9
40
39
Z01.1
ICD-10 Finland
Examination of ears and hearing
7.1
33.3
58
102
H92.0
ICD-10 Finland
Otalgia
7.4
21.4
33
50
H05
ICPC
Bleeding ear
119.8
20.9
22
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
13.6
97
457
B01AA03
ATC
warfarin; systemic
2.9
12.7
77
331
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
49.1
12.0
14
*
AA1AD
NOMESCO Finland
CT of head and brain
2.7
11.9
92
446
H02AB06
ATC
prednisolone; systemic
2.5
11.7
138
815
R04.0
ICD-10 Finland
Epistaxis
3.9
11.2
36
104
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
11.1
86
415
H65.3
ICD-10 Finland
Chronic mucoid otitis media
9.4
10.5
21
24
Z97.4
ICD-10 Finland
Presence of external hearing-aid
24.6
10.4
14
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
10.1
139
862
DAX08
NOMESCO Finland
Fitting of hearing aid
27.2
9.9
13
5
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
7.7
9.7
22
31
H29
ICPC
Ear symptom/complaint other
3.4
9.7
38
125
Z3229
NOMESCO Finland
Other healthcare associate professional
3.7
9.7
32
94
N03AX16
ATC
[U] pregabalin
2.6
9.6
73
346
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.5
9.5
81
405
R51.80
ICD-10 Finland
Headache
2.9
9.5
52
209
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
+∞
9.4
9
*
A02BC02
ATC
pantoprazole; systemic
2.4
9.3
181
1282
ZXA05
NOMESCO Finland
Left side
2.4
9.2
81
410
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
9.6
9.2
18
20
C03CA01
ATC
furosemide; systemic
2.3
9.1
102
574
WX110
NOMESCO Finland
Infiltration anesthesia
2.4
8.9
188
1367
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
8.9
47
185
C10AA05
ATC
atorvastatin; oral
2.2
8.8
119
720
L17
ICPC
Foot/toe symptom/complaint
2.3
8.8
84
441
H60.9
ICD-10 Finland
Otitis externa, unspecified
3.9
8.4
26
73
I50
ICD-10 Finland
Heart failure
5.0
8.2
18
38
WX892
NOMESCO Finland
Monitored bed care
3.3
8.2
32
105
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.6
8.1
53
232
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
8.1
121
756
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.5
8.1
20
47
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
8.1
86
470
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.7
7.9
26
76
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.1
7.8
34
119
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
46.4
7.8
9
*
Z02.7
ICD-10 Finland
Issue of medical certificate
3.4
7.6
28
88
A01
ICPC
Pain general/multiple sites
3.1
7.6
34
121
H93.1
ICD-10 Finland
Tinnitus
7.5
7.6
17
24
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
7.6
59
280
AN1
HP
Coronary angiography
2.7
7.5
43
176
R4110
NOMESCO Finland
Physiotherapy
2.2
7.4
87
491
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.2
7.4
76
407
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.6
7.4
47
203
Z3231
NOMESCO Finland
Registered nurse
2.1
7.3
88
502
H71
ICD-10 Finland
Cholesteatoma of middle ear
16.3
7.3
11
7
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
16.3
7.3
11
7
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.0
7.3
35
130
H65.2
ICD-10 Finland
Chronic serous otitis media
12.5
7.2
12
10
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
7.0
70
369
S18
ICPC
Laceration/cut
2.0
7.0
126
830
H53.1
ICD-10 Finland
Subjective visual disturbances
3.6
7.0
24
72
C07AB07
ATC
bisoprolol; oral
2.0
6.9
141
970
N02AX02
ATC
tramadol; systemic, rectal
2.0
6.9
121
790
H81.0
ICD-10 Finland
Ménière disease
11.4
6.9
12
11
H01
ICPC
Ear pain/earache
2.7
6.8
39
159
207
Kela drug reimbursment
Chronic arrhythmias
2.4
6.8
53
252
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
6.8
58
287
J01DB01
ATC
cefalexin; oral
2.4
6.8
214
1729
ZXD05
NOMESCO Finland
Urgent procedure
2.1
6.8
88
515
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
3.2
6.7
27
90
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
6.7
108
682
L28
ICPC
Limited function/disability (L)
2.3
6.7
56
274
I50.0
ICD-10 Finland
Congestive heart failure
3.0
6.7
30
107
TFP20
NOMESCO Finland
Cardiodefibrillation
3.0
6.7
30
107
B01AC04
ATC
clopidogrel; oral
2.3
6.6
59
297
S76
ICPC
Skin infection other
3.7
6.6
21
60
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.7
6.5
37
151
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
71.6
6.5
7
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.3
6.4
53
258
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
6.4
58
294
M79.6
ICD-10 Finland
Pain in limb
2.0
6.4
109
701
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
18.6
6.3
9
5
R60.9
ICD-10 Finland
Oedema, unspecified
3.6
6.3
21
62
R50.9
ICD-10 Finland
Fever, unspecified
2.4
6.3
50
239
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.2
6.3
17
43
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
+∞
6.3
6
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.2
6.3
25
83
XF402
NOMESCO Finland
ECG with work load test
2.7
6.2
35
142
J05AB01
ATC
aciclovir; systemic
2.2
6.2
60
312
S29
ICPC
Skin symptom/complaint other
2.3
6.1
53
263
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
10.4
6.1
11
11
R5120
NOMESCO Finland
Preparation of an aid
10.4
6.1
11
11
S01.3
ICD-10 Finland
Open wound of ear
10.4
6.1
11
11
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
6.1
37
156
B01AF02
ATC
apixaban; oral
2.5
6.0
42
189
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
165
949
3.08
16.63
29.7
15.2
1.45
1.27
inr
0.93
39
276
98
509
2.50
10.82
2.5
2.2
2.66
3.29
mg/l
1.89
88
440
146
917
2.38
10.41
12.2
7.0
1.20
1.21
mmol/l
1.14
136
850
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
26
63
4.48
10.16
6.6
2.5
0.27
0.35
u/ml
0.87
19
30
107
592
2.39
10.15
2.3
2.1
176.11
455.52
u/l
1.00
100
558
79
397
2.43
9.14
6.0
3.5
168.55
279.58
ng/l
0.48
62
329
109
631
2.27
9.08
4.8
3.0
2246.62
1527.96
ng/l
0.57
95
538
151
1011
2.20
8.63
13.5
7.7
1.20
1.21
mmol/l
1.45
135
875
138
899
2.16
8.37
7.5
5.1
35.27
35.52
g/l
0.20
128
860
170
1218
2.18
7.87
9.2
5.5
6.87
6.73
mmol/l
0.28
160
1133
135
893
2.08
7.64
3.4
2.6
—
—
—
0
0
83
457
2.21
7.58
2.8
1.9
1.10
1.35
mg/l
0.47
64
353
203
1575
2.40
7.55
9.9
7.4
83.35
82.17
u/l
0.15
197
1484
69
354
2.30
7.45
2.3
1.8
—
—
—
0
0
122
789
2.04
7.23
2.4
2.1
90.33
92.37
pmol/l
0.20
65
393
37
143
2.86
7.17
4.8
2.8
48.81
65.84
ml/min/173m2
1.72
16
67
119
775
2.00
6.80
5.6
3.9
25.82
44.46
ng/l
1.65
85
566
34
132
2.82
6.52
2.0
1.6
—
—
—
0
0
80
459
2.08
6.43
3.6
2.5
—
—
—
0
0
124
835
1.94
6.29
4.3
2.8
181.11
124.93
ug/l
0.74
115
771
163
1212
1.95
6.06
11.6
9.6
4.07
4.19
e9/l
0.29
137
1040
58
301
2.20
5.99
11.9
6.5
1.16
1.11
mmol/l
0.53
53
275
86
521
1.98
5.87
3.7
2.9
362.88
7877.35
umol/l
2.60
76
451
97
615
1.93
5.78
3.2
2.4
56.37
64.19
u/l
0.49
89
577
50
249
2.25
5.69
10.8
8.1
1.32
1.10
mmol/l
0.16
42
202
52
264
2.22
5.65
2.2
1.7
—
—
—
0
0
52
270
2.16
5.33
2.4
1.8
—
—
—
0
0
41
194
2.33
5.24
2.6
2.4
27.53
36.11
u/l
1.21
34
162
80
489
1.93
5.24
1.8
1.6
21.45
21.14
nmol/l
0.06
70
414
53
284
2.09
5.00
12.3
7.3
103.72
104.19
mmol/l
0.28
53
284
234
2044
2.69
4.97
25.5
14.7
24.18
25.85
mg/l
0.33
202
1603
186
1497
1.89
4.86
4.5
3.8
15.04
14.90
pmol/l
0.34
173
1339
65
379
1.96
4.85
4.0
2.8
2.05
2.94
e6/l
0.53
44
199
7
5
14.33
4.60
2.4
4.6
323.57
59.40
nmol/l
—
7
5
183
1479
1.83
4.55
4.9
4.0
12.68
12.24
mm/h
0.14
169
1359
33
155
2.30
4.28
1.3
1.7
—
—
—
0
0
111
791
1.71
4.21
4.6
3.2
—
—
—
0
0
213
1824
2.00
4.20
5.6
4.5
1.96
1.95
mu/l
0.07
199
1656
114
823
1.69
4.09
3.2
2.4
77.20
76.60
nmol/l
0.08
98
733
67
421
1.80
3.90
1.4
1.4
3.88
1.26
u/ml
0.55
14
110
239
2156
2.63
3.87
14.7
10.3
27.23
25.69
u/l
0.47
234
2080
18
66
2.86
3.84
1.8
1.6
—
—
—
0
0
214
1853
1.94
3.83
4.6
4.0
1.27
1.29
mmol/l
0.09
194
1695
64
400
1.80
3.78
3.3
2.8
1.43
0.92
e6/l
0.44
42
216
219
1917
1.99
3.71
4.9
4.4
5.96
6.01
mmol/l
0.21
203
1753
59
363
1.81
3.66
1.9
1.8
1102.93
1204.48
nmol/l
0.40
44
279
155
1235
1.65
3.65
3.4
3.0
—
—
—
0
0
218
1912
1.94
3.57
5.2
4.4
4.18
4.56
mmol/l
7.03
200
1769
222
1961
1.99
3.53
5.7
4.9
2.43
2.68
mmol/l
3.95
204
1805
97
694
1.64
3.47
4.0
3.3
2.36
2.35
mmol/l
0.21
87
626
217
1907
1.91
3.44
5.1
4.3
1.35
1.44
mmol/l
3.17
198
1752
14
50
2.90
3.14
1.6
1.4
332.78
281.64
ug/g
—
9
30
88
629
1.61
3.11
4.0
3.1
0.19
0.43
e6/l
2.28
68
467
161
1329
1.57
3.00
4.0
3.2
55.66
46.00
u/l
0.74
151
1240
10
27
3.81
2.91
1.7
1.3
—
—
—
0
0
244
2266
2.64
2.90
38.5
21.6
39.42
40.11
%
1.15
229
2138
244
2268
2.62
2.86
37.3
21.3
4.38
4.51
e12/l
2.86
238
2190
16
66
2.52
2.77
2.1
1.8
—
—
—
0
0
59
393
1.65
2.73
2.9
3.2
2.46
2.46
mmol/l
0.16
54
347
243
2267
2.42
2.59
37.5
21.3
234.41
246.55
e9/l
1.85
238
2200
123
978
1.50
2.58
4.1
3.9
0.00
0.00
estimate
0.50
16
200
12
44
2.81
2.58
1.8
1.7
—
—
—
0
0
12
44
2.81
2.58
1.8
1.7
—
—
—
0
0
16
69
2.41
2.54
2.3
1.9
—
—
—
0
0
19
89
2.23
2.52
2.4
2.5
—
—
—
0
0
25
133
1.97
2.41
2.5
1.3
—
—
—
0
0
124
999
1.47
2.38
4.3
4.0
0.00
0.00
estimate
-0.00
16
187
8
22
3.72
2.38
2.0
1.5
—
—
—
0
0
206
1842
1.61
2.35
6.9
5.7
40.15
40.12
mmol/mol
0.01
191
1717
12
47
2.63
2.30
2.9
1.6
—
—
—
0
0
122
985
1.46
2.29
5.7
5.4
0.00
0.00
estimate
-0.00
16
188
5
9
5.64
2.22
1.2
1.3
—
—
—
0
0
10
36
2.85
2.16
2.0
1.7
—
—
—
0
0
10
36
2.85
2.16
2.0
1.7
—
—
—
0
0
15
68
2.28
2.15
1.1
1.2
—
—
—
0
0
207
1872
1.55
2.04
23.2
13.6
77.55
80.27
ml/min/173m2
0.76
175
1549
8
26
3.14
2.03
1.1
1.0
—
—
—
0
0
5
11
4.61
1.95
3.8
1.8
128.00
74.45
umol/l
—
5
11
12
52
2.37
1.90
2.2
1.2
—
—
—
0
0
6
17
3.59
1.85
1.2
1.2
—
—
—
0
0
79
610
1.43
1.81
4.5
3.9
15.15
12.26
mg/mmol
0.12
51
392
6
18
3.39
1.75
1.2
1.6
—
—
—
0
0
6
18
3.39
1.75
1.2
1.6
—
—
—
0
0
6
18
3.39
1.75
1.2
1.6
—
—
—
0
0
11
48
2.35
1.73
2.4
1.7
180.50
282.13
u/ml
—
6
24
6
19
3.21
1.67
2.8
2.9
4.00
12.06
nmol/l
—
6
19
34
225
1.59
1.62
11.8
7.6
—
—
—
0
0
8
32
2.55
1.61
1.3
1.1
—
—
—
0
0
11
50
2.25
1.59
2.4
1.7
—
—
—
0
0
6
20
3.05
1.59
1.2
1.2
—
—
—
0
0
35
236
1.56
1.55
2.7
1.8
1.57
1.56
%
0.03
30
205
5
15
3.38
1.53
1.4
1.7
17.42
13.19
umol/l
—
5
15
9
37
2.48
1.49
1.4
1.3
—
—
—
0
0
9
39
2.35
1.44
2.4
1.2
—
—
—
0
0
5
16
3.17
1.44
1.8
1.6
—
—
—
0
0
197
1806
1.39
1.43
31.6
17.9
14.56
14.68
%
0.15
192
1777
6
23
2.65
1.37
4.2
2.3
—
—
—
0
0
25
164
1.58
1.26
5.8
7.1
0.63
1.60
mmol/l
0.96
15
124
12
63
1.95
1.25
1.8
1.5
—
—
—
0
0
9
45
2.04
1.24
1.2
1.2
—
—
—
0
0
91
758
1.31
1.24
4.4
4.7
2.00
2.51
ug/l
0.51
81
671
8
37
2.20
1.22
2.3
1.3
—
—
—
0
0
6
26
2.34
1.19
1.7
1.5
—
—
—
0
0
5
21
2.41
1.09
1.4
1.2
—
—
—
0
0
5
21
2.41
1.09
1.4
1.2
—
—
—
0
0
5
21
2.41
1.09
1.4
1.2
—
—
—
0
0
5
21
2.41
1.09
1.4
1.2
—
—
—
0
0
5
21
2.41
1.09
1.4
1.2
—
—
—
0
0
9
48
1.91
1.01
1.3
1.3
—
6.96
—
0
5
5
23
2.20
0.98
1.4
1.8
—
—
—
0
0
5
23
2.20
0.98
1.4
1.8
—
—
—
0
0
5
23
2.20
0.98
1.2
1.8
—
—
—
0
0
0
30
0.00
0.98
0.0
1.8
—
—
—
0
0
52
414
1.32
0.97
1.7
1.8
163415149.32
450.25
pmol/l
0.49
41
361
6
29
2.09
0.90
1.8
1.4
—
—
—
0
0
6
31
1.96
0.85
1.5
1.5
—
—
—
0
0
6
31
1.96
0.85
1.3
1.1
—
—
—
0
0
12
73
1.68
0.83
2.6
2.5
—
—
—
0
0
0
26
0.00
0.79
0.0
1.7
—
—
—
0
0
63
532
1.24
0.75
4.0
4.2
0.00
0.00
estimate
-0.00
16
179
37
292
1.31
0.75
1.5
1.3
1.71
14.53
u/ml
1.94
15
122
5
24
2.10
0.75
1.0
1.4
6.40
3.26
mg/l
—
5
24
5
27
1.87
0.69
1.2
1.3
—
—
—
0
0
5
27
1.87
0.69
1.4
1.7
—
—
—
0
0
5
27
1.87
0.69
1.0
1.9
19.45
20.36
ug/l
—
5
27
10
63
1.61
0.62
2.0
1.6
—
—
—
0
0
8
50
1.62
0.62
1.0
1.5
—
—
—
0
0
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
10
64
1.59
0.59
5.5
3.6
—
1.32
—
0
5
85
758
1.18
0.58
4.0
4.1
—
—
—
0
0
10
149
0.66
0.58
1.1
1.7
—
—
—
0
0
8
55
1.47
0.56
1.6
1.4
—
—
—
0
0
8
55
1.47
0.56
1.6
1.4
—
—
—
0
0
9
60
1.52
0.55
3.0
5.2
22.01
24.42
mmol/l
—
9
60
11
74
1.51
0.54
1.3
1.7
—
192.00
—
0
5
7
45
1.57
0.49
1.7
1.4
—
—
—
0
0
7
51
1.38
0.44
1.6
1.3
—
—
—
0
0
67
602
1.15
0.42
4.0
4.2
25.39
21.69
%
0.74
31
286
8
59
1.37
0.41
1.1
1.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
6
41
1.47
0.36
1.0
1.2
—
14.87
—
0
7
16
126
1.29
0.36
6.1
2.5
0.18
0.15
e6/l
0.10
16
119
17
136
1.27
0.34
1.2
1.1
159.29
128.18
iu/ml
—
8
51
22
188
1.19
0.26
2.1
2.1
—
—
—
0
0
26
226
1.17
0.26
1.7
1.4
—
—
—
0
0
14
114
1.24
0.25
1.1
1.2
140.77
372.16
u/ml
0.51
14
103
7
94
0.74
0.23
1.6
2.0
—
—
—
0
0
25
220
1.15
0.22
5.2
4.0
34.21
31.43
%
0.52
19
141
5
41
1.22
0.22
1.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
104.02
—
0
10
0
12
0.00
0.21
0.0
1.8
—
13.45
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
6
50
1.20
0.20
1.5
1.6
—
—
—
0
0
37
338
1.11
0.19
1.3
1.6
—
—
—
0
0
5
69
0.72
0.17
1.8
1.5
—
—
—
0
0
6
77
0.77
0.16
1.2
1.9
—
—
—
0
0
43
454
0.94
0.11
2.7
2.8
0.66
0.82
ug/l
0.65
35
289
12
107
1.13
0.08
1.2
1.3
—
—
—
0
0
8
75
1.07
0.07
1.3
1.1
—
—
—
0
0
8
75
1.07
0.07
1.3
1.1
—
—
—
0
0
19
177
1.08
0.07
2.1
2.0
—
—
—
0
0
32
313
1.03
0.01
1.4
1.3
101.30
33.67
iu/ml
—
8
120
21
213
0.98
0.00
2.0
3.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
7
70
1.00
-0.00
1.6
1.7
—
—
—
0
0
5
54
0.92
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.10
—
0
5
5
50
1.00
-0.00
1.6
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
11
110
1.00
-0.00
1.0
1.0
—
—
—
0
0
6
66
0.91
-0.00
1.2
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_OTORRHAGIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTORRHAGIA | 1.65 [1.23, 2.22] | 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.45 |
During the follow-up period (1.1.1998 — 31.12.2019), 153 out of 677 females with H8_OTORRHAGIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTORRHAGIA | 2.165 [1.52, 3.07] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 847 males with H8_OTORRHAGIA died.
Mortality risk
Mortality risk for people of age
years, who have H8_OTORRHAGIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.191% | 0.416% |
| 5 | 0.975% | 2.488% |
| 10 | 2.277% | 5.739% |
| 15 | 4.61% | 10.897% |
| 20 | 8.497% | 17.972% |
Relationships between endpoints
↥Index endpoint: H8_OTORRHAGIA – Otorrhagia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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