Lupus nephritis

M13_LUPUS_NEPHRITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

147

4. Check minimum number of events

None

147

5. Include endpoints

None

147

6. Filter based on genotype QC (FinnGen only)

137

Control definitions (FinnGen only)

Control exclude
AUTOIMMUNE

Extra metadata

Level in the ICD hierarchy
4

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 137 100 37
Unadjusted period prevalence (%) 0.03 0.04 0.02
Median age at first event (years) 40.53 38.65 45.63

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
147
Matched controls
1470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
374.0
244.5
125
22
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
209.3
146
*
P01BA02
ATC
hydroxychloroquine; oral
176.3
190.3
99
17
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
2999.1
120.7
100
*
L04AA06
ATC
mycophenolic acid; systemic
820.9
120.6
103
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
102.4
86
*
L04AX01
ATC
azathioprine; systemic
475.4
92.0
83
*
C03CA01
ATC
furosemide; systemic
21.0
81.4
98
128
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
33.6
81.0
58
28
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
360.4
78.8
73
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
40.3
74.9
49
18
M05BA04
ATC
alendronic acid; oral
28.9
71.8
54
29
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
20.8
71.4
116
224
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
28.0
64.3
48
25
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
574.5
44.7
42
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
11.5
44.3
59
81
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
15.2
42.7
43
39
H02AB04
ATC
methylprednisolone; systemic
10.1
41.0
62
99
205
Kela drug reimbursment
Chronic hypertension
10.0
40.9
63
103
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
40.5
37
*
ZX120
NOMESCO Finland
Intravenous
12.3
39.9
47
54
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
39.4
36
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
253.8
38.8
38
*
H02AB07
ATC
prednisone; oral
10.2
38.8
56
84
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
38.2
35
*
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
+∞
37.1
34
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
9.0
36.7
107
338
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
52.7
35.8
42
11
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
97.8
34.7
37
5
C09AA02
ATC
enalapril; systemic
8.5
33.3
56
99
H02AB06
ATC
prednisolone; systemic
8.8
32.4
115
425
KA1AE
NOMESCO Finland
Kidney ultrasound examination
50.6
32.2
38
10
A11CC03
ATC
alfacalcidol; systemic
75.7
31.7
35
6
M32
ICD-10 Finland
Systemic lupus erythematosus
+∞
30.3
28
*
TPH04
NOMESCO Finland
Cathetrisation of vein
7.0
30.1
67
157
C08CA02
ATC
felodipine; oral
12.1
28.7
32
33
A49.9
ICD-10 Finland
Bacterial infection, unspecified
9.5
28.2
39
54
TK800
NOMESCO Finland
Hemodialysis
89.4
26.9
29
*
C08CA01
ATC
amlodipine; oral
6.1
26.8
80
242
Z49.1
ICD-10 Finland
Extracorporeal dialysis
313.2
26.6
26
*
Z94.0
ICD-10 Finland
Kidney transplant status
298.7
25.5
25
*
A12AA04
ATC
calcium carbonate; oral
156.6
25.5
26
*
R50.9
ICD-10 Finland
Fever, unspecified
6.5
25.5
55
123
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
27.2
24.9
34
16
L04AD01
ATC
ciclosporin; systemic
81.9
24.8
27
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
6.4
23.0
48
103
H03AA01
ATC
levothyroxine sodium; systemic
8.2
22.9
35
54
127
Kela drug reimbursment
Transplant complication
95.0
22.4
24
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
21.4
20
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
20.1
21.3
32
20
N18.0
ICD-10 Finland
End-stage renal disease
243.0
21.2
21
*
B03XA02
ATC
darbepoetin alfa; parenteral
39.0
21.0
26
8
C08CA05
ATC
nifedipine; systemic
19.1
20.9
32
21
N17.9
ICD-10 Finland
Acute renal failure, unspecified
34.7
20.5
26
9
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
20.3
19
*
B01AA03
ATC
warfarin; systemic
7.1
20.1
35
62
L04AX03
ATC
methotrexate; systemic
19.5
19.8
30
19
J01MA12
ATC
levofloxacin; systemic
5.4
19.6
51
132
N18.8
ICD-10 Finland
Other chronic renal failure
64.1
19.5
22
*
137
Kela drug reimbursment
Uraemia requiring dialysis
+∞
19.2
18
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
216.5
19.0
19
*
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
+∞
18.1
17
*
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
+∞
18.1
17
*
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
18.1
17
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
18.1
17
*
B05DA
ATC
Isotonic solutions
+∞
18.1
17
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
+∞
18.1
17
*
Z49.2
ICD-10 Finland
Other dialysis
+∞
18.1
17
*
L93.0
ICD-10 Finland
Discoid lupus erythematosus
108.3
18.0
19
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
203.5
17.9
18
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
8.2
17.1
25
36
L04AA01
ATC
[U] ciclosporin
101.9
17.0
18
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
16.2
16.8
27
20
B01AB04
ATC
dalteparin; parenteral
8.2
16.6
24
34
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.6
16.6
53
160
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.9
16.4
46
125
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
8.3
16.2
23
32
B05DB
ATC
Hypertonic solutions
+∞
15.9
15
*
G05.8*M32.1
ICD-10 Finland
Encephalitis in systemic lupus erythematosus
+∞
15.9
15
*
L01BA01
ATC
methotrexate; systemic
+∞
15.9
15
*
ZX108
NOMESCO Finland
Inhalation
178.2
15.8
16
*
J01FF01
ATC
clindamycin; systemic
4.1
15.5
63
226
C02AC05
ATC
moxonidine; oral
24.2
15.2
21
10
H26.3
ICD-10 Finland
Drug-induced cataract
89.3
14.9
16
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
14.8
14
*
L04AD02
ATC
tacrolimus; systemic
82.7
13.8
15
*
1XC02, ,
NOMESCO Finland
+∞
13.8
13
*
N32.9
ICD-10 Finland
Bladder disorder, unspecified
+∞
13.8
13
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
+∞
13.8
13
*
C09CA01
ATC
losartan; oral
4.0
13.7
52
176
B03XA01
ATC
erythropoietin; parenteral
153.6
13.7
14
*
Z3231
NOMESCO Finland
Registered nurse
3.8
13.6
63
244
B07.9
ICD-10 Finland
Verruca simplex
13.4
13.4
23
20
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
7.0
13.4
22
36
N02AX02
ATC
tramadol; systemic, rectal
3.6
13.3
84
397
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.0
13.2
26
51
C08CA13
ATC
lercanidipine; oral
5.0
13.0
32
77
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
5.5
13.0
28
60
M04AA01
ATC
allopurinol; systemic
5.9
13.0
26
52
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.9
13.0
26
52
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.1
12.9
31
73
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
76.7
12.8
14
*
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
22.5
12.8
18
9
A02BC02
ATC
pantoprazole; systemic
4.4
12.8
118
706
C09CA06
ATC
candesartan; oral
3.8
12.7
52
184
A12AA12
ATC
[U] calcium acetate
+∞
12.7
12
*
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
12.7
12
*
XX9XE
NOMESCO Finland
Other ultrasound examination
+∞
12.7
12
*
C10AA05
ATC
atorvastatin; oral
3.5
12.5
67
283
R80
ICD-10 Finland
Isolated proteinuria
41.4
12.5
15
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.7
12.4
33
85
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
12.7
12.0
21
19
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
11.6
11
*
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
11.6
11
*
V03AE02
ATC
sevelamer; oral
+∞
11.6
11
*
L01AA01
ATC
cyclophosphamide; systemic
129.7
11.6
12
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
14.3
11.5
19
15
Z2446
NOMESCO Finland
Social worker
5.7
11.4
23
46
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.5
11.3
52
197
XF400
NOMESCO Finland
ECG with 12 standard connections
4.3
11.1
34
97
B01AB10
ATC
tinzaparin; parenteral
4.6
11.0
30
78
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
5.7
10.9
22
44
TK820
NOMESCO Finland
Peritoneal dialysis
+∞
10.5
10
*
L01BB01, ,
ATC
+∞
10.5
10
*
N16.4*M32.1
ICD-10 Finland
Renal tubulo-interstitial disorders in systemic lupus erythematosus
+∞
10.5
10
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
25.6
10.5
14
6
Z2221
NOMESCO Finland
Medical doctor
3.2
10.3
64
289
Z3226
NOMESCO Finland
Physiotherapist
3.6
10.1
42
148
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.4
10.1
28
74
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.7
9.6
19
22
J05AB11
ATC
valaciclovir; oral
3.5
9.6
40
141
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.4
9.6
44
165
K65.0
ICD-10 Finland
Acute peritonitis
106.6
9.5
10
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
9.5
9
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
9.5
9
*
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
9.5
9
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
9.5
9
*
G73.7*M32.1
ICD-10 Finland
Myopathy in systemic lupus erythematosus
+∞
9.5
9
*
D07AB08
ATC
desonide; topical
4.1
9.4
29
83
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
11.1
9.3
17
17
C10AA01
ATC
simvastatin; oral
3.1
9.3
53
226
J01MA14
ATC
moxifloxacin; systemic
4.4
9.3
26
69
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.1
9.2
28
79
R4110
NOMESCO Finland
Physiotherapy
3.0
9.0
56
250
Z3229
NOMESCO Finland
Other healthcare associate professional
4.9
8.9
21
48
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.8
8.9
72
371
J05AB01
ATC
aciclovir; systemic
3.1
8.8
51
218
C07AB02
ATC
metoprolol; systemic
3.5
8.8
35
119
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
53.2
8.8
10
*
A12BA01
ATC
potassium chloride; oral
21.6
8.6
12
6
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.8
8.5
78
425
E0000UV, ,
ATC
2.8
8.5
78
425
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
11.8
8.5
15
14
V03AE01
ATC
polystyrene sulfonate; oral
95.3
8.5
9
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
95.3
8.5
9
*
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
8.4
8
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
+∞
8.4
8
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
8.4
8
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
8.4
8
*
J01FA06
ATC
roxithromycin; oral
2.8
8.4
73
387
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.0
8.4
19
42
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
12.7
8.3
14
12
D64.9
ICD-10 Finland
Anaemia, unspecified
4.8
8.2
20
47
L88
ICPC
Rheumatoid/seropositive arthritis
35.5
8.2
10
*
UJF32
NOMESCO Finland
Coloscopy
3.1
8.2
42
167
I10
ICD-10 Finland
Essential (primary) hypertension
2.7
8.2
83
474
I50.9
ICD-10 Finland
Heart failure, unspecified
4.9
8.2
19
43
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
23.6
8.1
11
5
A02BC03
ATC
lansoprazole; oral
2.9
8.1
52
234
N19
ICD-10 Finland
Unspecified kidney failure
14.1
8.0
13
10
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.1
8.0
40
156
AA1AD
NOMESCO Finland
CT of head and brain
3.1
8.0
43
175
E000001, ,
ATC
3.1
7.9
41
164
XW000
NOMESCO Finland
Bone marrow biopsy
16.2
7.9
12
8
TPH07
NOMESCO Finland
Cathetrisation of artery
4.6
7.8
20
49
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
47.6
7.8
9
*
C02CA01
ATC
prazosin; oral
26.6
7.7
10
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.1
7.7
23
64
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
14.4
7.5
12
9
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
14.4
7.5
12
9
321
Kela drug reimbursment
Paricalcitol and cinacalcet
84.2
7.5
8
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.4
7.4
20
51
J01MA02
ATC
ciprofloxacin; systemic
2.6
7.4
65
341
ZXE20
NOMESCO Finland
More than three and less than five hours
3.5
7.4
29
97
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
7.2
7.4
17
26
N05.8
ICD-10 Finland
Unspecified nephritic syndrome, other
+∞
7.3
7
*
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
+∞
7.3
7
*
V03AE03
ATC
lanthanum carbonate; oral
+∞
7.3
7
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
+∞
7.3
7
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.8
7.3
24
71
GD1AD
NOMESCO Finland
Thorax CT examination
7.3
7.0
16
24
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
14.7
7.0
11
8
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
14.7
7.0
11
8
H04.10
ICD-10 Finland
Dry eye syndrome
3.5
7.0
26
84
C02EA02, ,
ATC
11.8
6.9
12
11
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
6.9
49
230
C07AG02
ATC
carvedilol; oral
7.8
6.9
15
21
C07AB07
ATC
bisoprolol; oral
2.5
6.8
67
369
UJF30
NOMESCO Finland
Ileoscopy through colon
4.2
6.8
19
50
NH3EA
NOMESCO Finland
Feet X-ray examination with load
23.8
6.8
9
*
ZXE00
NOMESCO Finland
One hour or less
2.5
6.6
71
405
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.5
6.5
16
27
C09AA05
ATC
ramipril; oral
3.0
6.5
33
129
N17.8
ICD-10 Finland
Other acute renal failure
72.9
6.5
7
*
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
72.9
6.5
7
*
H05BX01
ATC
cinacalcet; oral
72.9
6.5
7
*
M01AE01
ATC
ibuprofen; systemic, rectal
0.4
6.5
104
1275
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
6.4
29
106
J01MA06
ATC
norfloxacin; oral
3.3
6.4
26
89
3AC01, ,
NOMESCO Finland
28.0
6.3
8
*
L04AA13
ATC
[U] leflunomide
+∞
6.3
6
*
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
+∞
6.3
6
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
+∞
6.3
6
*
N25.0
ICD-10 Finland
Renal osteodystrophy
+∞
6.3
6
*
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
+∞
6.3
6
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
+∞
6.3
6
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
+∞
6.3
6
*
WX002
NOMESCO Finland
Sedation and analgesia
3.0
6.2
32
126
A10AC01
ATC
insulin (human); parenteral
6.1
6.2
16
29
A63.0
ICD-10 Finland
Anogenital (venereal) warts
6.1
6.2
16
29
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
9.2
6.2
12
14
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
13.3
6.2
10
8
R07.4
ICD-10 Finland
Chest pain, unspecified
2.6
6.2
44
206
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.5
6.1
17
34
NF1AA
NOMESCO Finland
Hip X-ray examination
4.4
6.1
16
40
ZXA10
NOMESCO Finland
Bilateral
2.9
6.1
33
134
B01AB05
ATC
enoxaparin; parenteral
2.5
6.0
51
259

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
112
215
18.68
68.69
14.9
2.7
210.43
92.09
mg/l
2.28
103
128
114
225
19.12
68.39
19.1
3.1
48.69
15.77
mg/mmol
2.22
106
130
98
204
12.41
53.78
9.3
2.2
2.56
9.25
e6/l
1.06
98
179
56
8
111.54
53.72
11.5
1.0
48.15
—
iu/ml
—
27
0
75
115
12.27
52.61
6.9
1.8
25.86
23.94
%
0.63
70
104
61
75
13.19
50.15
7.6
3.6
0.17
1.35
mmol/l
1.15
53
60
61
78
12.66
48.65
4.7
2.4
1.66
1.55
%
0.39
61
73
52
53
14.63
48.37
3.2
2.6
66.60
76.28
e9/l
0.80
28
39
129
449
16.30
42.05
23.8
5.3
1.21
1.22
mmol/l
0.35
114
389
111
329
10.69
42.01
14.2
2.6
15.13
256.89
e6/l
0.61
104
238
52
65
11.83
41.66
9.1
5.0
—
—
—
0
0
133
491
18.94
40.60
24.2
4.4
—
—
—
0
0
85
209
8.27
37.67
13.3
2.3
484.45
543.84
mosm/kgh2o
2.06
85
177
96
271
8.33
36.97
15.0
3.0
7.40
7.40
ph
0.03
19
55
39
38
13.61
36.76
5.0
1.1
14.57
—
u/ml
—
6
0
113
386
9.33
35.53
17.0
3.1
31.15
35.83
e6/l
0.09
106
259
98
293
8.03
35.22
15.2
2.6
0.11
0.27
e6/l
1.89
92
202
96
297
7.43
32.74
13.8
2.6
—
—
—
0
0
66
143
7.56
32.40
2.9
1.2
1027.27
334.81
titre
2.23
44
27
40
59
8.94
27.44
8.6
5.8
0.04
0.00
%
0.48
23
19
40
64
8.21
25.50
9.3
5.6
0.64
0.78
%
0.14
25
23
75
224
5.79
25.26
8.2
3.6
—
—
—
0
0
38
60
8.19
24.45
9.0
5.8
0.41
0.81
%
0.46
22
21
65
176
5.83
24.36
11.5
2.4
0.82
3.25
e6/l
2.22
49
87
110
471
6.31
23.79
25.0
7.9
0.00
0.01
e9/l
0.45
104
370
38
64
7.66
23.01
9.3
5.6
0.00
0.09
%
0.79
23
23
56
140
5.85
22.76
2.5
1.5
—
—
—
0
0
105
458
5.52
21.44
8.6
2.8
5.86
5.96
ph
—
7
41
26
30
10.31
21.33
9.7
5.0
0.37
0.11
g/l
2.37
21
13
117
567
6.21
20.72
15.5
4.2
0.00
0.00
estimate
-0.00
24
102
76
265
4.87
20.41
14.7
6.4
—
—
—
0
0
31
21
18.36
20.03
1.4
1.0
3.65
2.71
u/ml
—
20
7
115
561
5.82
19.87
10.7
3.0
0.00
0.01
estimate
0.50
25
104
116
570
5.91
19.85
10.7
3.0
0.00
0.00
estimate
-0.00
24
94
72
247
4.75
19.60
7.4
2.9
—
—
—
0
0
34
61
6.95
19.23
6.4
2.7
7.42
7.42
ph
—
5
10
137
794
11.66
18.95
18.9
3.6
—
—
—
0
0
51
141
5.01
18.01
3.8
3.2
0.82
0.81
mmol/l
0.15
51
134
29
47
7.44
17.96
1.5
3.6
—
—
—
0
0
136
839
9.30
15.93
16.2
2.8
17.02
9.16
mm/h
7.13
131
770
45
128
4.63
15.09
2.2
1.6
1182.83
1112.06
nmol/l
0.20
38
99
30
60
6.03
15.06
11.5
2.7
—
—
—
0
0
24
39
7.16
14.71
7.6
2.5
—
—
—
0
0
22
15
17.01
14.10
1.4
1.5
—
—
—
0
0
62
241
3.72
13.28
2.5
1.6
—
—
—
0
0
62
244
3.66
12.99
1.8
1.4
2.40
2.19
g/l
0.56
43
164
72
317
3.49
12.58
3.8
2.4
—
—
—
0
0
39
115
4.25
12.28
2.7
1.5
—
—
—
0
0
84
412
3.42
12.24
18.2
8.8
1.42
1.14
inr
1.20
27
127
43
137
4.02
12.18
3.2
1.9
—
—
—
0
0
18
16
12.64
10.39
6.8
2.3
4.12
5.93
e9/l
1.27
18
16
18
17
11.89
10.11
7.5
3.1
63.50
61.00
%
0.21
18
17
18
18
11.22
9.84
10.9
2.2
—
—
—
0
0
71
352
2.97
9.55
2.3
1.7
105.76
97.94
pmol/l
0.69
39
184
15
11
15.01
9.41
1.2
1.2
1.04
1.08
ratio
—
9
5
15
11
15.01
9.41
1.8
1.2
—
—
—
0
0
19
38
5.59
9.38
1.3
1.1
—
—
—
0
0
21
32
7.47
9.06
1.3
1.5
—
—
—
0
0
12
6
21.60
8.62
2.8
6.3
85.25
76.83
%
—
12
6
12
6
21.60
8.62
2.7
6.3
8.67
11.33
%
—
12
6
19
27
7.91
8.58
4.5
2.9
—
—
—
0
0
15
14
11.78
8.51
1.3
8.3
—
—
—
0
0
21
51
4.64
8.31
10.1
6.3
22.93
24.45
mmol/l
0.88
21
51
7
0
+∞
7.35
6.0
0.0
—
—
—
0
0
96
612
2.64
7.25
8.0
3.5
5.99
6.19
mmol/l
0.77
91
551
10
5
21.30
7.24
1.7
1.4
—
—
—
0
0
12
10
12.93
7.22
2.0
1.1
—
—
—
0
0
26
83
3.59
7.13
14.4
4.6
—
—
—
0
0
11
8
14.72
7.01
2.2
5.6
48.63
37.00
%
—
11
8
60
310
2.58
7.00
2.6
1.9
—
—
—
0
0
10
6
17.73
6.84
1.1
1.0
—
—
—
0
0
26
89
3.33
6.39
2.0
1.4
—
—
—
0
0
6
0
+∞
6.29
25.2
0.0
4.95
—
mmol/l
—
6
0
28
102
3.16
6.22
10.7
5.3
103.79
104.05
mmol/l
0.10
28
102
12
14
9.22
6.19
12.3
8.6
—
—
—
0
0
63
357
2.34
5.79
3.3
2.3
—
—
—
0
0
13
20
7.02
5.70
2.0
1.1
—
—
—
0
0
11
13
9.04
5.67
13.4
7.6
73.77
65.54
%
0.76
11
13
11
13
9.04
5.67
1.0
1.5
—
—
—
0
0
17
48
3.87
5.51
2.9
1.5
—
—
—
0
0
8
5
16.79
5.47
2.0
1.0
—
—
—
0
0
14
26
5.83
5.38
4.9
2.7
21.76
24.59
mmol/l
1.29
14
26
9
8
11.88
5.36
2.0
2.8
1504.56
2218.75
ml
—
9
8
9
8
11.88
5.36
3.9
4.5
—
—
—
0
0
13
22
6.37
5.36
2.5
1.7
—
—
—
0
0
141
1220
4.81
5.30
49.4
9.7
16.22
20.84
mg/l
1.34
130
900
11
16
7.33
5.05
2.0
2.9
—
—
—
0
0
30
128
2.69
4.99
1.6
1.3
—
—
—
0
0
15
34
4.79
4.91
2.5
1.9
8.59
8.54
kpa
0.03
15
34
11
17
6.90
4.87
8.7
1.5
—
—
—
0
0
10
14
7.57
4.74
1.3
1.1
—
—
—
0
0
60
363
2.10
4.46
4.2
2.9
55.04
22.42
ng/l
0.70
46
198
31
145
2.44
4.25
1.7
1.3
76.00
69.19
ug/g
0.09
24
111
14
42
3.58
4.16
11.9
3.8
0.69
0.69
%
0.02
14
42
46
258
2.14
4.12
2.1
1.8
2.27
0.79
mg/l
1.25
40
195
11
22
5.31
4.09
1.3
1.3
—
—
—
0
0
34
170
2.30
4.01
3.9
3.0
217.83
244.29
ng/l
0.05
29
101
8
11
7.61
3.91
4.3
8.7
11.61
11.93
%
—
8
11
10
19
5.56
3.90
2.2
1.4
—
—
—
0
0
14
44
3.41
3.89
11.9
3.7
0.82
1.45
%
1.32
14
44
9
15
6.31
3.88
8.4
1.7
8.98
9.09
kpa
—
9
15
9
15
6.31
3.88
1.1
3.9
—
—
—
0
0
9
15
6.31
3.88
8.4
1.7
4.50
4.96
kpa
—
9
15
6
5
12.42
3.79
2.0
3.0
546.00
898.00
e6/l
—
6
5
47
274
2.05
3.76
4.3
3.0
—
—
—
0
0
49
291
2.03
3.73
12.9
3.2
0.00
0.00
estimate
-0.00
19
96
6
6
10.35
3.53
7.8
3.7
—
—
—
0
0
22
96
2.52
3.47
23.1
3.1
—
—
—
0
0
7
10
7.28
3.40
7.0
3.0
—
—
—
0
0
100
774
1.91
3.30
4.4
3.1
—
—
—
0
0
6
8
7.76
3.08
1.3
1.3
34.50
33.88
pg
—
6
8
52
335
1.85
3.03
13.0
2.6
—
—
—
0
0
12
37
3.44
3.01
8.3
6.2
—
—
—
0
0
12
37
3.44
3.01
3.8
2.8
26.42
20.46
s
0.71
12
28
5
5
10.28
3.00
3.0
6.8
46.20
30.00
%
—
5
5
5
5
10.28
3.00
1.6
1.0
—
—
—
0
0
52
337
1.84
2.96
3.3
2.1
66.65
55.84
u/l
1.35
52
323
7
13
5.59
2.90
1.0
1.2
—
—
—
0
0
14
54
2.76
2.79
17.6
2.4
—
—
—
0
0
5
6
8.57
2.77
1.6
1.3
—
—
—
0
0
68
487
1.74
2.72
2.1
1.9
—
—
—
0
0
5
7
7.34
2.57
1.2
1.3
—
—
—
0
0
110
911
1.82
2.56
5.2
2.9
14.28
14.28
pmol/l
0.01
99
843
43
274
1.80
2.54
1.3
1.2
0.63
0.66
u/ml
—
7
71
8
22
3.78
2.40
1.3
1.1
—
—
—
0
0
19
92
2.22
2.40
1.5
1.4
—
—
—
0
0
5
8
6.42
2.39
1.2
2.3
—
—
—
0
0
5
8
6.42
2.39
1.6
1.0
—
—
—
0
0
5
8
6.42
2.39
1.2
1.3
—
—
—
0
0
9
28
3.35
2.35
5.3
3.0
1.31
1.52
%
—
9
22
8
23
3.62
2.30
2.0
2.5
3.52
3.77
mmol/l
—
8
23
6
13
4.76
2.29
1.2
1.1
—
—
—
0
0
9
29
3.24
2.27
5.3
3.0
0.74
0.82
%
—
9
24
5
9
5.70
2.23
1.2
1.2
—
—
—
0
0
125
1094
1.95
2.22
52.2
11.7
14.62
14.60
%
0.01
125
1080
11
43
2.68
2.13
8.1
6.6
0.71
0.74
%
0.10
11
43
0
55
0.00
2.12
0.0
1.2
—
—
—
0
0
16
76
2.24
2.11
1.4
1.2
—
—
—
0
0
10
37
2.82
2.11
1.4
1.1
—
—
—
0
0
11
44
2.62
2.06
7.4
6.5
1.14
1.81
%
1.32
11
44
6
15
4.12
2.06
1.0
1.1
—
—
—
0
0
8
26
3.19
2.04
1.8
2.4
—
—
—
0
0
9
32
2.93
2.04
2.4
2.4
—
—
—
0
0
11
46
2.50
1.90
2.8
1.8
—
—
—
0
0
16
82
2.07
1.77
1.3
1.3
146.73
133.64
u/ml
0.04
11
72
7
24
3.01
1.74
3.6
2.0
—
—
—
0
0
7
26
2.77
1.60
12.4
3.1
—
—
—
0
0
24
148
1.74
1.56
1.3
1.2
—
—
—
0
0
8
33
2.50
1.56
3.5
1.8
—
—
—
0
0
7
27
2.67
1.53
2.4
2.2
0.57
245.86
e6/l
—
7
21
124
1119
1.69
1.51
5.7
3.5
1.84
1.73
mu/l
0.56
118
1046
38
514
0.65
1.48
3.9
2.2
—
—
—
0
0
17
96
1.87
1.46
1.2
1.2
—
—
—
0
0
13
69
1.97
1.33
1.5
1.4
—
—
—
0
0
18
107
1.78
1.33
1.3
1.1
—
—
—
0
0
10
183
0.51
1.22
1.4
1.4
—
—
—
0
0
5
109
0.44
1.05
1.0
1.5
—
—
—
0
0
34
252
1.45
1.05
9.3
3.0
1.01
1.02
kg/l
—
6
36
18
116
1.63
1.02
1.5
1.3
—
—
—
0
0
137
1304
1.74
0.90
36.4
8.8
—
—
—
0
0
29
215
1.43
0.90
1.2
1.2
1.37
2.39
u/ml
0.38
13
91
29
216
1.43
0.88
1.3
1.2
23.49
20.87
iu/ml
0.08
11
68
8
44
1.86
0.87
1.5
1.1
—
—
—
0
0
6
32
1.91
0.82
1.2
1.1
—
—
—
0
0
0
25
0.00
0.80
0.0
1.0
—
0.43
—
0
10
5
27
1.88
0.69
3.0
3.9
22.00
18.56
mg/l
—
5
16
12
79
1.57
0.65
3.8
2.1
—
—
—
0
0
0
20
0.00
0.61
0.0
1.0
—
1.99
—
0
9
24
193
1.29
0.47
1.8
1.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
0.77
—
0
5
10
77
1.32
0.27
1.8
3.1
5.21
7.49
e9/l
—
10
72
19
161
1.21
0.25
1.4
2.0
—
—
—
0
0
5
37
1.36
0.24
1.0
3.1
74.00
3850.94
u/ml
—
5
31
5
41
1.23
0.22
2.2
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
79.96
—
0
11
0
10
0.00
0.21
0.0
1.0
—
251.00
—
0
5
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
15.9
—
894.15
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
22.4
—
1529.38
—
0
13
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
5
67
0.74
0.17
2.2
1.4
—
—
—
0
0
6
75
0.79
0.16
2.0
1.4
—
—
—
0
0
6
75
0.79
0.16
2.0
1.4
—
—
—
0
0
141
1393
1.30
0.16
64.0
14.4
37.83
40.36
%
4.87
135
1323
13
150
0.85
0.15
1.5
1.2
—
—
—
0
0
118
1158
1.10
0.12
5.4
3.6
5.33
5.67
mmol/l
5.20
110
1080
114
1118
1.09
0.12
48.1
11.9
329.18
332.77
g/l
4.47
114
1110
5
45
1.11
0.10
5.0
3.5
—
—
—
0
0
20
184
1.10
0.09
1.4
1.5
—
—
—
0
0
6
74
0.80
0.08
2.0
1.4
—
—
—
0
0
6
74
0.80
0.08
2.0
1.4
—
—
—
0
0
38
387
0.98
0.01
1.8
1.5
—
—
—
0
0
6
67
0.89
0.00
1.2
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
57.57
—
0
7
0
9
0.00
-0.00
0.0
1.2
—
1.53
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
1.10
—
0
9
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
9.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
12.54
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
0.54
—
0
6
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: M13_LUPUS_NEPHRITIS – Lupus nephritis

GWS hits: 2

This endpoint is excluded (different definition than used in FinnGen).