Other congenital malformations of urinary system

Q17_OTHER_CONGEN_MALFO_URINARY_SYSTEM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q64
  • Cause of death: ICD-10 Q64

2 out of 7 registries used, show all original rules.

197

4. Check minimum number of events

None

197

5. Include endpoints

None

197

6. Filter based on genotype QC (FinnGen only)

188

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_URINARY_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q6[0-4]
Name in latin
Aliae malformationes congenitae systematis urinarii

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2018 615 1402
Only index persons 1583 486 1097
Unadjusted period prevalence (%)
Whole population 0.03 0.02 0.04
Only index persons 0.03 0.02 0.04
Median age at first event (years)
Whole population 7.52 12.17 5.45
Only index persons 13.99 21.46 10.68

-FinnGen-

Key figures

All Female Male
Number of individuals 188 72 116
Unadjusted period prevalence (%) 0.04 0.03 0.05
Median age at first event (years) 27.44 42.41 18.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
197
Matched controls
1970
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UKC02
NOMESCO Finland
Cystoscopy
28.6
130.3
116
94
Q64.4
ICD-10 Finland
Malformation of urachus
+∞
64.1
58
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
18.2
61.3
55
41
Q64.2
ICD-10 Finland
Congenital posterior urethral valves
+∞
55.9
51
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
10.5
52.3
73
105
XKD00
NOMESCO Finland
Uroflowmetry
9.4
49.2
76
123
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
10.8
46.6
60
77
J01EA01
ATC
trimethoprim; systemic
7.0
41.0
94
227
Z94.0
ICD-10 Finland
Kidney transplant status
124.7
38.3
40
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
49.7
33.7
40
10
N18.8
ICD-10 Finland
Other chronic renal failure
53.4
33.3
39
9
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
196.9
32.8
33
*
A11CC03
ATC
alfacalcidol; systemic
48.1
32.6
39
10
127
Kela drug reimbursment
Transplant complication
40.1
31.4
39
12
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
45.1
30.6
37
10
Q64.38
ICD-10 Finland
Other atresia and stenosis of urethra and bladder neck
+∞
30.0
28
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
175.8
29.5
30
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
49.1
27.8
33
8
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.9
27.7
43
67
L04AA06
ATC
mycophenolic acid; systemic
33.9
26.4
34
12
WX408
NOMESCO Finland
General anesthesy, balanced
4.7
26.0
99
347
L04AX01
ATC
azathioprine; systemic
10.9
26.0
30
32
KCD40
NOMESCO Finland
Excision of urachus
+∞
24.5
23
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
6.0
24.0
51
109
L04AD02
ATC
tacrolimus; systemic
42.1
23.7
29
8
XKC03
NOMESCO Finland
Water cystometry
27.0
23.5
32
14
TPH04
NOMESCO Finland
Cathetrisation of vein
4.7
23.0
71
209
A12AA04
ATC
calcium carbonate; oral
35.9
22.2
28
9
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.0
22.0
59
154
B03XA01
ATC
erythropoietin; parenteral
+∞
21.2
20
*
204
Kela drug reimbursment
Leukemia lymphatica
25.9
21.1
29
13
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
123.1
21.0
22
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
123.1
21.0
22
*
ZXE20
NOMESCO Finland
More than three and less than five hours
5.0
20.9
55
141
J01MA02
ATC
ciprofloxacin; systemic
4.0
20.7
94
363
Q62.7
ICD-10 Finland
Congenital vesico-uretero-renal reflux
+∞
20.1
19
*
N18.0
ICD-10 Finland
End-stage renal disease
+∞
20.1
19
*
137
Kela drug reimbursment
Uraemia requiring dialysis
61.5
19.4
22
*
KH1EE
NOMESCO Finland
Urologic ultrasound examination
110.7
18.9
20
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
15.9
18.5
30
22
1530
FHL
Urethrocystoscopy
58.4
18.3
21
*
Q64.1
ICD-10 Finland
Exstrophy of urinary bladder
+∞
18.0
17
*
H02AB04
ATC
methylprednisolone; systemic
4.7
17.8
49
129
Z3226
NOMESCO Finland
Physiotherapist
4.0
17.8
70
241
ZXE00
NOMESCO Finland
One hour or less
3.6
17.8
114
541
L04AD01
ATC
ciclosporin; systemic
17.0
17.8
28
19
H02AB09
ATC
hydrocortisone; systemic
7.7
17.4
26
38
ZXE10
NOMESCO Finland
More than one and less than three hours
3.5
17.0
96
418
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
+∞
16.9
16
*
KC1JB
NOMESCO Finland
Miktiocystography with X-ray
185.0
16.8
17
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
44.2
16.7
20
5
V03AE01
ATC
polystyrene sulfonate; oral
52.3
16.3
19
*
ZXD10
NOMESCO Finland
Scheduled procedure
3.4
16.2
104
487
TK800
NOMESCO Finland
Hemodialysis
24.6
15.9
22
10
R4110
NOMESCO Finland
Physiotherapy
3.5
15.8
82
335
Q64.8
ICD-10 Finland
Other specified congenital malformations of urinary system
+∞
15.8
15
*
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
173.2
15.7
16
*
ZXD05
NOMESCO Finland
Urgent procedure
3.4
15.0
82
345
B07.9
ICD-10 Finland
Verruca simplex
7.3
14.8
23
35
KDD52
NOMESCO Finland
Urethroscopic excision of urethral valve
+∞
14.8
14
*
Q64.9
ICD-10 Finland
Congenital malformation of urinary system, unspecified
+∞
14.8
14
*
TKC20
NOMESCO Finland
Catheterisation of bladder
7.1
14.4
23
36
Z3231
NOMESCO Finland
Registered nurse
3.2
14.4
90
408
RD210, ,
NOMESCO Finland
7.4
14.3
22
33
J01XE01
ATC
nitrofurantoin; oral
26.1
14.1
19
8
7536A
ICD-9 Finland
Congenital anomalies of urinary system, Atresia and stenosis of urethra and bladder neck[OBSTRUCTIO URETHRAE ET COLLI VESICAE CONGENITA]
+∞
13.7
13
*
Q64.0
ICD-10 Finland
Epispadias
+∞
13.7
13
*
Q64.34
ICD-10 Finland
Congenital prolapse of: urinary meatus
+∞
13.7
13
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
5.7
13.6
27
53
WX402
NOMESCO Finland
General anaesthesia
3.3
13.3
66
259
XF602
NOMESCO Finland
Bloodpressure monitoring
20.8
13.2
19
10
L04AA01
ATC
[U] ciclosporin
30.8
13.2
17
6
ZXA00
NOMESCO Finland
Right side
3.3
12.8
61
233
Q62.0
ICD-10 Finland
Congenital hydronephrosis
+∞
12.6
12
*
205
Kela drug reimbursment
Chronic hypertension
3.8
12.6
45
142
KA1AE
NOMESCO Finland
Kidney ultrasound examination
15.7
12.6
20
14
R50.9
ICD-10 Finland
Fever, unspecified
3.4
12.5
55
199
Z2446
NOMESCO Finland
Social worker
3.9
12.5
42
127
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
12.3
97
491
R31
ICD-10 Finland
Unspecified haematuria
5.4
12.3
26
54
ZXD20
NOMESCO Finland
Day surgery
3.9
12.2
42
129
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
6.4
12.1
21
36
G04AC01, ,
ATC
16.0
12.1
19
13
KDV12
NOMESCO Finland
Urethroscopic internal urethrotomy
49.9
12.0
14
*
N35.9
ICD-10 Finland
Urethral stricture, unspecified
49.9
12.0
14
*
5901A
ICD-9 Finland
Infections of kidney, Acute pyelonephritis
127.1
11.6
12
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.1
11.4
21
38
ZX120
NOMESCO Finland
Intravenous
4.3
11.4
33
89
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
11.4
46
157
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
9.8
11.1
22
25
B05DA
ATC
Isotonic solutions
46.1
11.1
13
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
46.1
11.1
13
*
K06.18
ICD-10 Finland
Another gingival hyperplasia
29.9
10.9
14
5
Z49.0
ICD-10 Finland
Preparatory care for dialysis
63.5
10.7
12
*
5AB14, ,
NOMESCO Finland
63.5
10.7
12
*
Z2221
NOMESCO Finland
Medical doctor
2.8
10.6
75
353
C08CA01
ATC
amlodipine; oral
2.9
10.6
64
277
Q64.31
ICD-10 Finland
Congenital stricture of: urethra
+∞
10.5
10
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
10.5
10
*
KBJ00
NOMESCO Finland
Cutaneous ureterostomy
+∞
10.5
10
*
ZXA05
NOMESCO Finland
Left side
3.1
10.5
53
207
B03XA02
ATC
darbepoetin alfa; parenteral
20.1
10.4
15
8
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
15.7
10.2
16
11
602
Kela drug reimbursment
Children's severe malnutrition
11.5
10.0
18
17
R33
ICD-10 Finland
Retention of urine
5.7
9.8
19
36
C08CA02
ATC
felodipine; oral
5.5
9.8
20
40
N30.0
ICD-10 Finland
Acute cystitis
3.6
9.8
36
115
B05DB
ATC
Hypertonic solutions
57.9
9.7
11
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
18.7
9.5
14
8
G04BD04
ATC
oxybutynin; oral, transdermal
5.1
9.5
21
45
TPH07
NOMESCO Finland
Cathetrisation of artery
3.7
9.5
33
101
J01CA08
ATC
pivmecillinam; oral
2.7
9.5
72
348
Q64.6
ICD-10 Finland
Congenital diverticulum of bladder
+∞
9.4
9
*
Q62.2
ICD-10 Finland
Congenital megaloureter
+∞
9.4
9
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.4
9.4
39
135
JN3AD
NOMESCO Finland
Abdominal CT examination
3.9
9.0
29
84
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.9
8.8
20
44
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
52.4
8.8
10
*
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
17.3
8.7
13
8
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
8.6
61
283
R4190
NOMESCO Finland
Nutritional therapy
3.9
8.6
27
77
5850B
ICD-9 Finland
Chronic renal failure[INSUFFICIENTIA RENIS CHRONICA CUM URAEMIA]
+∞
8.4
8
*
KAC00
NOMESCO Finland
Nephrectomy
+∞
8.4
8
*
KCH96
NOMESCO Finland
Other reconstructive operation on bladder
+∞
8.4
8
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.1
8.3
18
38
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
23.2
8.1
11
5
WX002
NOMESCO Finland
Sedation and analgesia
3.0
8.0
39
148
TKC22
NOMESCO Finland
Catheterisation instruction
15.9
7.8
12
8
V03AE02
ATC
sevelamer; oral
46.9
7.8
9
*
Z49.2
ICD-10 Finland
Other dialysis
26.2
7.6
10
*
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
26.2
7.6
10
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.6
7.4
26
80
Q64.30
ICD-10 Finland
Congenital bladder neck obstruction
+∞
7.3
7
*
75360
ICD-8 Finland
Congenital anomalies of urinary system, Valvula urethrae cum hydronephrosi
+∞
7.3
7
*
N19
ICD-10 Finland
Unspecified kidney failure
9.8
6.9
13
14
4AA09, ,
NOMESCO Finland
41.5
6.8
8
*
TJF80
NOMESCO Finland
Ostomy education
41.5
6.8
8
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
41.5
6.8
8
*
WX882
NOMESCO Finland
High dependency care
3.8
6.6
21
60
SPAT1262
SPAT
Handing over of treatment supplies
2.9
6.6
34
132
J01MA06
ATC
norfloxacin; oral
3.3
6.6
26
86
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.2
6.6
81
473
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
4.0
6.5
19
51
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
72.1
6.5
7
*
V03AG01
ATC
sodium cellulose phosphate; systemic
72.1
6.5
7
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
72.1
6.5
7
*
UKD02
NOMESCO Finland
Urethroscopy
72.1
6.5
7
*
KBV00
NOMESCO Finland
Insertion of stent into ureter
72.1
6.5
7
*
N13.7
ICD-10 Finland
Vesicoureteral-reflux-associated uropathy
72.1
6.5
7
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
6.4
78
453
WX320
NOMESCO Finland
Spinalanesthesy
2.6
6.4
44
199
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.3
6.4
26
88
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
18.8
6.3
9
5
75350
ICD-8 Finland
Congenital anomalies of urinary system, Extrophy of urinary bladder
+∞
6.3
6
*
75361
ICD-8 Finland
Congenital anomalies of urinary system, Valvula urethrae, hydronephrosi non indicata
+∞
6.3
6
*
Q60.0
ICD-10 Finland
Renal agenesis, unilateral
+∞
6.3
6
*
K03.28
ICD-10 Finland
Other erosion of teeth
10.5
6.1
11
11
N02AX02
ATC
tramadol; systemic, rectal
2.2
6.1
73
421

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
82
216
5.79
31.44
7.4
2.7
2.38
2.06
e6/l
0.10
55
116
112
432
4.69
25.96
12.8
2.8
31.30
26.18
e6/l
0.14
97
333
92
306
4.76
25.88
6.8
2.6
—
—
—
0
0
106
393
4.67
25.87
11.7
2.7
0.31
0.25
e6/l
0.23
90
298
106
395
4.64
25.65
11.6
2.6
—
—
—
0
0
116
494
4.28
22.72
15.3
3.3
150.72
45.38
e6/l
0.96
100
347
85
295
4.31
22.02
10.6
2.2
4.06
4.32
e6/l
0.11
85
268
53
131
5.17
21.05
17.0
8.7
22.96
23.55
mmol/l
0.84
53
131
154
832
4.90
21.03
12.7
3.5
6.40
4193.57
e6/l
—
5
14
48
109
5.50
21.00
3.3
4.1
67.64
74.34
e9/l
0.64
36
83
79
268
4.25
20.96
9.1
2.5
524.99
597.28
mosm/kgh2o
1.92
79
232
58
171
4.39
18.32
21.2
8.4
0.15
1.30
mmol/l
1.55
52
132
89
357
3.72
18.11
15.2
3.7
7.38
7.40
ph
1.63
15
60
31
54
6.63
17.73
4.6
1.5
—
—
—
0
0
127
657
3.63
17.05
11.9
4.5
0.00
0.00
estimate
-0.00
24
137
20
5
44.16
16.68
5.1
2.8
—
—
—
0
0
157
943
4.27
16.52
12.9
3.5
—
—
—
0
0
127
668
3.54
16.38
8.6
3.3
0.00
0.00
estimate
-0.00
25
128
126
663
3.50
16.17
8.6
3.3
0.00
0.00
estimate
-0.00
26
136
79
312
3.56
16.15
5.3
3.5
4409.08
5387.92
umol/l
0.08
72
275
55
173
4.02
15.71
25.9
9.4
—
—
—
0
0
27
26
11.85
14.77
1.9
3.2
—
—
—
0
0
75
314
3.24
13.60
6.7
3.5
—
—
—
0
0
118
650
3.03
13.03
34.7
7.9
1.22
1.22
mmol/l
0.19
109
564
30
68
5.02
12.88
3.6
1.4
191.80
254.95
u/ml
0.50
25
38
23
22
11.68
12.64
1.5
1.2
—
—
—
0
0
111
604
2.92
12.32
3.7
2.6
—
—
—
0
0
23
25
10.26
11.87
3.0
2.4
—
—
—
0
0
84
402
2.90
11.73
8.0
3.5
7.47
8.59
mmol/l
1.46
77
360
37
109
3.95
11.36
3.2
1.4
—
—
—
0
0
70
309
2.96
11.26
9.1
4.4
—
—
—
0
0
47
164
3.45
11.24
34.3
9.6
24.44
24.96
mmol/l
0.48
47
164
49
189
3.12
9.87
2.8
2.1
—
—
—
0
0
20
41
5.32
9.54
1.8
2.8
1.63
1.38
g/l
0.50
15
35
94
523
2.52
9.23
8.5
9.2
1.16
1.16
inr
0.03
22
158
48
191
3.00
9.11
3.7
5.3
4.73
8.88
umol/l
1.44
42
163
20
28
7.82
9.00
2.3
1.9
—
—
—
0
0
81
429
2.51
8.74
8.4
3.2
2.41
2.37
mmol/l
1.92
72
391
81
437
2.45
8.32
9.8
8.2
—
—
—
0
0
46
188
2.89
8.26
2.5
1.5
—
—
—
0
0
40
152
3.05
8.17
12.8
7.9
106.05
104.36
mmol/l
1.26
40
152
69
349
2.50
8.12
1.9
1.7
1.45
1.36
mmol/l
0.31
63
309
112
704
2.37
8.06
5.2
7.5
9.79
13.11
umol/l
3.11
107
661
76
406
2.42
7.90
4.0
2.4
—
—
—
0
0
71
370
2.44
7.78
8.1
2.7
—
—
—
0
0
58
275
2.57
7.77
7.1
3.4
104.71
60.30
mg/l
0.80
47
186
150
1106
2.49
7.05
13.0
6.9
99.42
88.99
u/l
1.09
144
1029
32
118
3.04
6.84
31.0
5.1
10.20
9.59
kpa
0.80
32
111
124
852
2.23
6.75
13.8
7.3
2.06
2.04
e9/l
0.09
113
760
57
286
2.40
6.66
8.2
3.9
18.97
9.16
mg/mmol
0.99
43
185
39
164
2.72
6.56
27.9
5.4
7.38
7.43
ph
—
8
6
14
19
7.84
6.54
18.6
2.7
—
—
—
0
0
120
824
2.17
6.41
13.8
7.4
0.04
0.04
e9/l
0.70
105
709
35
141
2.80
6.38
27.6
5.3
—
—
—
0
0
50
241
2.44
6.36
3.1
1.5
—
—
—
0
0
16
39
4.38
6.22
1.8
1.8
—
—
—
0
0
29
107
3.01
6.18
1.9
1.4
—
—
—
0
0
119
822
2.13
6.17
13.9
7.4
0.60
0.57
e9/l
0.85
105
708
47
226
2.42
5.98
3.5
3.1
147.44
398.38
ng/l
1.11
34
149
61
329
2.24
5.96
2.6
2.5
2.91
3.08
mg/l
0.21
53
293
31
122
2.83
5.89
15.2
10.2
1.12
1.45
mmol/l
1.58
31
117
120
844
2.08
5.78
15.3
7.9
0.18
0.19
e9/l
0.37
110
750
130
943
2.11
5.75
15.8
10.8
4.02
3.91
e9/l
0.23
118
810
34
143
2.66
5.69
2.9
2.1
70.52
28.89
u/l
0.84
29
122
156
1221
2.33
5.60
5.9
4.6
37.85
38.60
mmol/mol
0.49
149
1161
57
306
2.21
5.59
2.6
1.6
—
—
—
0
0
111
767
2.02
5.52
17.5
7.8
—
—
—
0
0
171
1400
2.68
5.44
5.5
4.0
2.76
2.83
mmol/l
0.49
160
1315
114
811
1.96
5.05
11.9
5.3
6.26
6.54
mmol/l
0.75
108
755
140
1077
2.04
4.86
7.0
4.0
12.78
8.41
mm/h
2.34
130
1001
14
30
4.94
4.78
1.2
1.2
—
—
—
0
0
12
23
5.48
4.53
16.0
2.4
—
—
—
0
0
36
174
2.31
4.47
1.6
1.6
—
—
—
0
0
38
189
2.25
4.41
2.6
2.9
2.43
2.43
mmol/l
0.02
29
164
7
6
12.03
4.31
1.1
1.0
—
—
—
0
0
161
1334
2.13
4.15
4.6
3.4
1.42
1.27
mmol/l
1.33
149
1250
64
396
1.91
4.13
3.2
2.0
—
—
—
0
0
105
761
1.81
4.07
18.5
9.5
0.00
0.00
e9/l
0.78
85
607
165
1389
2.16
3.93
5.3
3.6
1.30
1.41
mmol/l
4.03
154
1305
165
1395
2.13
3.79
5.4
3.7
4.47
4.66
mmol/l
1.61
158
1318
18
67
2.86
3.77
21.7
10.4
—
—
—
0
0
12
29
4.34
3.77
18.9
2.8
—
—
—
0
0
16
57
2.97
3.62
8.8
7.8
0.66
0.72
%
0.30
16
57
10
21
4.96
3.60
4.4
15.1
83.56
72.44
%
—
10
21
20
81
2.64
3.59
16.4
4.6
1.25
1.22
mmol/l
2.61
20
72
6
6
10.26
3.52
1.8
2.7
1.43
1.16
umol/l
—
6
6
27
130
2.25
3.37
1.7
1.7
—
—
—
0
0
16
60
2.81
3.32
8.8
7.5
1.41
1.46
%
0.05
16
60
10
24
4.33
3.24
4.5
14.5
—
—
—
0
0
65
432
1.75
3.23
2.1
1.8
99.58
98.91
pmol/l
0.04
32
225
16
61
2.77
3.22
1.5
1.2
—
—
—
0
0
52
326
1.81
3.13
7.8
3.4
1.01
1.01
kg/l
—
8
44
27
136
2.14
3.03
3.9
2.9
9.36
9.81
g/l
0.22
27
125
55
354
1.77
3.03
4.5
4.4
1.55
1.90
ug/l
0.53
48
316
51
322
1.79
2.99
2.4
2.7
1.42
1.10
mg/l
0.32
36
242
183
1650
2.54
2.99
25.0
10.1
—
—
—
0
0
6
9
6.83
2.89
1.2
1.1
—
—
—
0
0
6
9
6.83
2.89
1.2
1.0
—
—
—
0
0
31
169
1.99
2.83
1.3
1.8
1197.74
1256.03
nmol/l
0.12
19
133
28
149
2.02
2.73
1.5
1.5
—
—
—
0
0
12
43
2.91
2.70
6.3
3.8
—
—
—
0
0
8
21
3.92
2.49
6.1
3.0
15.61
18.10
%
—
8
9
11
38
3.00
2.46
1.2
1.3
—
—
—
0
0
9
27
3.44
2.42
22.6
3.3
4.99
5.10
kpa
—
9
27
9
27
3.44
2.42
18.0
3.3
11.07
8.65
kpa
—
9
27
10
33
3.14
2.39
1.1
1.1
—
—
—
0
0
5
8
6.38
2.38
1.4
1.0
1334.40
1558.88
miu/ml
—
5
8
10
34
3.04
2.31
1.3
1.1
—
—
—
0
0
6
13
4.72
2.29
1.5
1.0
—
—
—
0
0
113
919
1.54
2.29
3.9
3.0
—
—
—
0
0
21
109
2.04
2.20
7.2
4.9
0.00
0.27
%
—
10
33
6
14
4.38
2.16
2.5
4.0
6.18
7.35
mmol/l
—
6
14
6
14
4.38
2.16
3.7
21.7
13.72
11.81
%
—
6
14
6
14
4.38
2.16
2.5
4.0
1.43
1.49
mmol/l
—
6
14
26
147
1.89
2.15
2.0
1.4
—
—
—
0
0
21
110
2.02
2.15
7.2
5.0
0.00
0.18
%
1.25
12
34
34
210
1.75
2.13
3.3
2.6
0.87
0.74
ug/l
0.12
20
120
21
111
2.00
2.10
6.5
4.5
0.30
0.72
%
—
10
38
22
119
1.96
2.07
7.1
4.8
0.38
0.93
%
1.22
13
44
175
1597
1.86
2.02
33.3
11.4
20.10
21.31
mg/l
0.26
151
1131
52
366
1.57
1.98
12.0
3.5
0.00
0.00
estimate
-0.00
20
131
5
11
4.63
1.95
2.4
1.5
—
—
—
0
0
148
1302
1.55
1.89
4.7
3.6
5.66
5.74
mmol/l
0.50
140
1209
8
28
2.93
1.88
9.6
3.4
44.25
56.75
%
—
8
28
8
28
2.93
1.88
7.5
3.2
2.99
4.41
e9/l
—
8
28
17
87
2.04
1.86
1.2
1.2
—
—
—
0
0
7
23
3.12
1.81
6.1
5.0
—
—
—
0
0
21
118
1.87
1.78
14.6
3.0
—
—
—
0
0
12
56
2.22
1.65
1.1
1.1
—
—
—
0
0
10
42
2.45
1.64
4.9
2.8
—
—
—
0
0
10
42
2.45
1.64
2.8
1.5
—
—
—
0
0
5
14
3.63
1.62
2.0
1.6
—
—
—
0
0
22
130
1.78
1.61
18.3
8.8
-1.02
0.70
mmol/l
1.59
17
101
6
20
3.06
1.59
1.2
3.4
—
—
—
0
0
12
57
2.18
1.58
2.3
2.1
—
—
—
0
0
190
1815
2.32
1.50
42.3
17.1
40.32
43.87
%
0.76
181
1734
9
38
2.43
1.47
1.1
3.3
—
—
—
0
0
7
28
2.55
1.46
1.4
4.0
—
—
—
0
0
6
23
2.66
1.38
1.0
1.2
—
—
—
0
0
10
47
2.19
1.36
1.5
1.6
—
—
—
0
0
57
441
1.41
1.34
1.7
1.4
—
—
—
0
0
9
45
2.05
1.25
1.6
1.2
—
—
—
0
0
23
149
1.62
1.24
1.7
1.4
—
—
—
0
0
25
168
1.56
1.17
1.3
1.2
—
—
—
0
0
18
111
1.68
1.17
1.3
1.4
228.38
426.82
u/ml
0.37
18
102
127
1135
1.33
1.13
3.5
3.6
14.79
14.64
pmol/l
0.29
120
1049
9
48
1.92
1.02
1.7
1.3
—
—
—
0
0
33
244
1.42
0.99
1.2
1.3
13.43
26.34
iu/ml
1.04
14
77
5
23
2.20
0.98
2.4
3.3
4.20
15.04
%
—
5
23
0
30
0.00
0.98
0.0
1.4
—
—
—
0
0
17
109
1.61
0.97
2.4
2.3
17.32
15.95
au/ml
—
5
11
14
85
1.70
0.97
1.4
1.5
—
—
—
0
0
6
27
2.26
0.94
2.3
4.8
20.92
23.57
mg/l
—
6
15
6
27
2.26
0.94
4.0
2.0
—
—
—
0
0
62
519
1.28
0.84
2.3
1.9
—
—
—
0
0
24
174
1.43
0.81
1.3
1.2
—
—
—
0
0
6
33
1.84
0.79
12.3
9.0
—
—
—
0
0
12
75
1.64
0.77
1.1
1.2
—
—
—
0
0
35
275
1.33
0.75
2.5
2.7
261.75
125.24
ug/g
0.42
28
223
9
56
1.64
0.73
1.1
2.5
—
—
—
0
0
31
240
1.35
0.73
1.3
1.3
1.28
9.11
u/ml
—
10
90
5
25
2.03
0.73
3.8
2.3
16.80
139.18
ug/min
—
5
14
0
21
0.00
0.60
0.0
1.7
—
0.55
—
0
16
6
99
0.59
0.53
1.0
1.1
—
—
—
0
0
15
201
0.73
0.52
1.2
1.3
—
—
—
0
0
11
76
1.47
0.49
2.6
4.0
5.03
4.81
pmol/l
0.26
11
68
52
455
1.19
0.47
1.5
1.5
2.37
2.22
g/l
0.18
34
261
7
49
1.44
0.46
1.0
1.2
—
—
—
0
0
7
50
1.41
0.45
1.0
1.1
—
—
—
0
0
14
104
1.37
0.44
10.9
3.3
—
—
—
0
0
5
35
1.44
0.39
2.8
1.5
—
—
—
0
0
11
80
1.40
0.39
1.5
1.4
345.64
325.45
mu/l
0.08
11
75
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
2.4
—
—
—
0
0
11
82
1.36
0.35
1.6
2.3
4.65
5.76
ug/l
0.20
11
74
142
1364
1.15
0.34
4.3
4.1
2.05
1.89
mu/l
0.68
134
1264
25
211
1.21
0.33
3.1
1.9
—
—
—
0
0
10
74
1.37
0.33
3.4
2.6
—
—
—
0
0
13
102
1.29
0.31
1.5
1.5
—
—
—
0
0
22
185
1.21
0.31
1.0
1.2
—
—
—
0
0
5
74
0.67
0.26
1.6
2.6
—
—
—
0
0
47
428
1.13
0.26
4.1
3.3
16.65
32.83
ng/l
1.06
31
254
5
37
1.36
0.23
1.4
1.2
—
—
—
0
0
20
172
1.18
0.23
1.6
2.2
10.66
14.40
nmol/l
1.32
20
166
0
11
0.00
0.21
0.0
4.8
—
1.94
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
275.00
—
0
5
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
13
155
0.83
0.21
1.5
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
1.52
—
0
14
15
166
0.90
0.10
1.4
1.9
—
—
—
0
0
15
166
0.90
0.10
1.5
1.8
—
—
—
0
0
5
48
1.04
0.09
24.2
5.1
—
—
—
0
0
15
165
0.90
0.09
1.4
2.0
—
—
—
0
0
27
287
0.93
0.08
1.7
1.6
—
—
—
0
0
15
164
0.91
0.08
1.4
1.9
—
—
—
0
0
10
89
1.13
0.07
1.1
1.8
14.66
15.21
iu/l
—
10
73
48
491
0.97
0.03
1.4
1.4
3.13
1.24
u/ml
—
8
111
12
113
1.07
0.02
1.3
2.3
—
—
—
0
0
13
123
1.06
0.01
1.2
2.2
—
—
—
0
0
55
554
0.99
0.00
2.9
2.3
—
—
—
0
0
10
102
0.98
0.00
21.9
4.9
—
—
—
0
0
12
125
0.96
0.00
1.5
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
5.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
29.17
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
4.44
—
0
7
8
88
0.91
0.00
1.0
1.8
6.29
6.95
u/l
—
8
71
0
6
0.00
0.00
0.0
37.0
—
0.66
—
0
6
0
6
0.00
0.00
0.0
1.2
—
6.07
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.5
—
3.91
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
1.1
1.1
—
—
—
0
0
31
310
1.00
-0.00
3.8
3.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
5
49
1.02
-0.00
6.0
4.6
23.24
10.09
umol/l
—
5
39
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
2.4
1.5
—
—
—
0
0
6
69
0.87
-0.00
11.8
4.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
5.76
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_OTHER_CONGEN_MALFO_URINARY_SYSTEM and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_OTHER_CONGEN_MALFO_URINARY_SYSTEM.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: Q17_OTHER_CONGEN_MALFO_URINARY_SYSTEM – Other congenital malformations of urinary system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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