Other effects of reduced temperature

ST19_OTHER_EFFEC_REDUCED_TEMPE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — T69 Cause of death: ICD-10 — T69 2 out of 7 registries used, show all original rules.	77
4. Check minimum number of events None	77
5. Include endpoints None	77
6. Filter based on genotype QC (FinnGen only)	77

Control definitions (FinnGen only)

Control exclude: ST19_OTHER_UNSPE_EFFEC_EXTER_CAUSES

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: T6[6-9]|T7[0-8]
Name in latin: Alii effectus caloris deminuti

NAME	ST19_OTHER_EFFEC_REDUCED_TEMPE
CONTROL_EXCLUDE	ST19_OTHER_UNSPE_EFFEC_EXTER_CAUSES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	T69
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	T69
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other effects of reduced temperature based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	77	43	34
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	47.33	42.77	53.11

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
67: Matched controls
669

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

T69.1

ICD-10 Finland

Chilblains

+∞

28.1

T69.8

ICD-10 Finland

Other specified effects of reduced temperature

+∞

23.3

T69.9

ICD-10 Finland

Effect of reduced temperature, unspecified

+∞

12.9

T69.0

ICD-10 Finland

Immersion hand and foot

+∞

9.6

X31

ICD-10 Finland

Exposure to excessive natural cold

+∞

8.5

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

6.9

7.5

C03CA01

ATC

furosemide; systemic

4.4

6.5

M48.0

ICD-10 Finland

Spinal stenosis

6.7

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3037522) Nuclear Ab [Titer] in Serum

4.87

9.67

2.2

1.3

748.00

566.67

titre

—

(42870588) Differential panel, method unspecified - Blood

195

3.73

7.54

8.8

5.5

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

6.92

7.14

2.4

2.0

—

(3006315) Basophils [#/volume] in Blood

302

3.64

6.51

7.5

6.0

0.05

0.04

e9/l

0.88

267

(40768443) Skin Pathology biopsy report

7.51

6.48

1.4

1.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

3.95

6.42

1.9

1.5

—

(3013115) Eosinophils [#/volume] in Blood

315

3.61

6.30

8.8

6.2

0.18

e9/l

0.18

282

(3004588) Protein electrophoresis panel - Serum or Plasma

4.79

6.26

1.4

2.0

—

(3019198) Lymphocytes [#/volume] in Blood

307

3.54

6.24

6.6

6.0

1.79

1.77

e9/l

0.08

279

(3001604) Monocytes [#/volume] in Blood

301

3.44

6.07

6.8

6.0

0.63

0.57

e9/l

0.84

267

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

107

3.35

5.56

1.4

1.2

18.83

26.75

iu/ml

0.34

(3013650) Neutrophils [#/volume] in Blood by Automated count

359

3.26

5.10

9.0

10.5

4.49

4.13

e9/l

0.57

315

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

110

2.88

4.18

2.1

1.6

—

(3004616) Nuclear Ab [Presence] in Serum

9.47

3.86

1.3

1.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

132

2.61

3.64

1.4

2.45

2.29

g/l

0.23

(3037467) Urinalysis macro (dipstick) panel - Urine

417

2.58

3.25

6.7

4.3

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

133

2.44

3.14

2.0

2.8

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

5.44

3.14

1.1

—

(3021788) Differential panel - Synovial fluid

8.01

3.11

1.0

1.3

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

6.29

3.09

1.4

1.0

—

(3023420) DNA double strand Ab [Units/volume] in Serum

10.56

3.02

1.8

1.2

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

251

2.24

2.99

6.8

8.7

1.22

1.21

mmol/l

0.10

220

(3021879) Hepatitis B virus core Ab [Presence] in Serum

3.12

2.99

1.5

1.4

—

(3015736) pH of Urine

225

2.24

2.98

4.2

3.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

217

2.24

2.96

2.2

1.9

95.76

97.09

pmol/l

0.06

103

(3042936) Bacteria identified in Isolate by Culture

2.57

2.86

2.1

2.5

—

(3020630) Protein [Mass/volume] in Serum or Plasma

2.99

2.79

1.7

1.9

66.47

66.46

g/l

0.00

(3013512) EKG study

167

2.18

2.61

5.7

4.0

—

(3021589) Normoblasts [#/volume] in Blood

263

2.08

2.54

11.8

9.5

0.00

e9/l

0.00

217

(3007853) Bacteria identified in Skin by Aerobe culture

2.51

2.54

3.2

1.6

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

100

2.35

2.49

1.5

1.3

31.11

13.27

u/ml

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

138

2.20

2.48

2.3

1.9

—

(3000494) Fungus identified in Specimen by Culture

2.68

2.46

1.3

1.9

—

(3044640) Blood type and Crossmatch panel - Blood

179

2.11

2.44

2.4

2.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

285

2.04

2.41

4.8

4.9

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

140

2.16

2.38

1.2

0.58

0.61

u/ml

—

(3018095) Leukocytes [#/volume] in Urine

216

2.03

2.32

4.0

3.4

19.62

85.15

e6/l

0.73

155

(3021960) Folate [Moles/volume] in Serum or Plasma

135

2.13

2.25

1.8

1.5

19.99

19.82

nmol/l

0.02

114

(3037756) Immunofixation for Serum or Plasma

5.85

2.25

1.4

1.8

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

576

2.54

2.13

4.5

4.6

1.93

1.90

mu/l

0.08

511

(40758558) Short blood count panel - Blood

132

2.06

2.03

5.1

7.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

207

1.93

2.02

5.0

2.8

—

(3000764) Benzodiazepines [Presence] in Urine

2.95

2.01

2.9

1.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

3.97

1.97

1.3

1.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.45

1.97

1.5

2.0

—

(3027944) Amphetamines [Presence] in Urine

2.86

1.94

2.9

1.2

—

(3028300) Cannabinoids [Presence] in Urine

2.86

1.94

3.0

1.2

—

(3027008) Opiates [Presence] in Urine

2.86

1.94

2.9

1.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

273

1.87

1.92

8.1

10.5

1.21

mmol/l

0.11

226

(3032080) INR in Blood by Coagulation assay

219

1.89

1.92

9.4

8.0

1.05

1.21

inr

—

(3031040) Bacteria [#/volume] in Urine by Automated count

411

1.93

1.88

5.5

3.9

—

74.43

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

4.37

1.85

3.2

1.1

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.96

1.85

1.1

2.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

231

1.84

1.82

4.2

3.4

29.67

33.73

ng/l

0.10

151

(40761535) Cells panel - Urine sediment

2.59

1.76

5.2

2.8

—

(3021601) Nitrite [Presence] in Urine by Test strip

309

1.79

1.70

7.5

5.0

0.00

estimate

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.67

1.65

1.3

1.1

—

(3035350) Ketones [Presence] in Urine by Test strip

311

1.77

1.65

5.6

3.6

0.00

estimate

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

3.74

1.64

2.8

1.6

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

159

1.85

1.62

4.2

3.2

1976.26

1570.62

ng/l

0.19

132

(3033658) Prothrombin time (PT) actual/Normal

135

1.88

1.58

3.5

3.4

92.82

90.72

0.13

135

(3011397) Hemoglobin [Presence] in Urine by Test strip

135

1.88

1.58

3.9

3.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

3.49

1.55

1.8

1.7

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

3.49

1.55

1.8

1.7

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

3.49

1.55

1.8

1.7

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

3.49

1.55

1.8

1.7

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

137

1.85

1.51

1.9

1.8

0.86

1.18

mg/l

0.35

106

(3009261) Glucose [Presence] in Urine by Test strip

318

1.71

1.47

5.5

3.7

0.00

estimate

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

3.27

1.46

1.8

1.7

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.27

1.46

1.8

1.3

—

(3019060) Gas panel - Arterial blood

2.35

1.42

4.9

16.5

—

(3023368) Bacteria identified in Blood by Culture

140

1.80

1.40

6.3

4.5

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

3.07

1.38

1.0

1.5

—

(3026782) Osmolality of Urine

116

1.85

1.38

3.6

2.6

531.26

533.08

mosm/kgh2o

0.01

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

133

1.80

1.36

1.2

1.7

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

2.62

1.33

1.7

1.4

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.90

1.30

1.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

467

1.73

1.30

3.7

4.0

14.59

14.79

pmol/l

0.24

413

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.23

1.22

4.4

2.3

216.50

124.82

ng/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.17

1.19

1.6

1.8

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.46

1.16

3.9

3.8

25.51

24.54

mmol/l

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

2.38

1.13

1.9

1.6

—

(3016879) Cocaine [Presence] in Urine

2.30

1.11

3.4

1.2

—

(4010399)

1.86

0.98

1.4

1.5

—

(3019225) pH of Specimen

1.94

0.97

6.1

—

(3000492) Spirometry study

1.83

0.96

1.2

1.3

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.82

0.95

1.0

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

164

1.57

0.95

6.8

4.7

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.24

0.94

2.5

2.2

—

(40761511) CBC panel - Blood by Automated count

672

2.10

0.85

23.3

12.9

—

(36304419) Bacteria [Presence] in Urine

162

1.50

0.78

3.5

2.6

—

(3050129) First trimester maternal screen panel - Serum or Plasma

2.16

0.76

1.8

1.3

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

2.16

0.76

2.8

1.2

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

593

1.62

0.75

4.7

4.3

5.73

5.90

mmol/l

0.43

531

(3044889) 12 lead EKG panel

407

0.71

0.74

4.9

3.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.99

0.72

1.8

1.7

—

(3045414) Leukocytes [Presence] in Urine

1.99

0.72

3.2

1.5

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.62

0.71

1.8

1.5

—

(1002224) Polysomnography panel

1.84

0.67

1.0

1.1

—

(3029937) Albumin [Presence] in Urine by Test strip

180

1.40

0.59

6.2

3.6

0.00

estimate

—

(3012544) pH of Venous blood

1.62

0.59

7.0

4.4

—

(3018418) pH of Serum or Plasma

171

1.40

0.59

5.8

4.3

7.41

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.46

0.54

2.1

1.3

—

(3022145) Colonoscopy Study observation

1.46

0.54

1.4

1.3

—

(3009508) Creatinine [Moles/volume] in Urine

183

1.37

0.53

5.7

3.3

8.32

8.02

mmol/l

0.12

149

(36660697) Celiac disease serology panel - Serum

1.50

0.48

1.4

1.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

587

1.40

0.48

20.2

12.6

83.23

85.15

ml/min/173m2

0.23

468

(3019832) Treponema pallidum Ab [Presence] in Serum

1.49

0.44

1.7

1.8

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.65

0.44

7.2

27.9

—

(40761536) Microorganisms panel - Urine sediment

1.45

0.44

8.0

3.7

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.41

0.0

4.6

—

37.36

—

(40768793) Breast Pathology biopsy report

0.00

0.41

0.0

1.3

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.40

0.0

1.4

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.46

0.40

4.2

4.3

70.58

52.24

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.39

0.0

1.6

—

(21494755) Public health laboratory ask at order entry panel

0.63

0.38

2.0

1.3

—

(1761868) Lipid panel - Serum or Plasma

229

0.77

0.37

2.1

2.9

—

(3009542) Hematocrit [Volume Fraction] of Blood

586

1.30

0.33

23.1

14.2

40.02

40.29

0.08

440

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.41

0.32

2.4

5.0

1.23

1.22

mmol/l

—

(3000991) Gas panel - Venous blood

1.41

0.32

8.3

9.4

—

(3003694) ABO and Rh group [Type] in Blood

177

1.26

0.32

1.6

1.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.30

0.29

2.3

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

105

1.29

0.27

1.4

1.3

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.38

0.24

4.6

2.5

2.18

1.35

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.1

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.21

0.0

1.3

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.7

—

3.16

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

253

1.17

0.21

6.6

3.7

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.21

0.0

1.7

—

2.86

—

(3012516) Albumin [Mass/volume] in Urine

166

1.19

0.20

5.8

3.5

168.36

77.64

mg/l

0.38

106

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.20

0.0

2.3

—

117.58

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.20

0.0

1.6

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.1

—

(3020682) Albumin/Creatinine [Ratio] in Urine

177

1.18

0.19

6.6

4.3

5.72

13.11

mg/mmol

0.93

112

(3002256) Pathology report gross observation

1.22

0.17

1.1

1.2

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

611

0.85

0.17

4.9

4.3

1.48

1.44

mmol/l

0.29

556

(40768797) Stomach Pathology biopsy report

1.24

0.16

1.4

1.2

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

117

0.83

0.14

3.7

2.7

0.54

0.85

ug/l

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.17

0.10

5.6

4.7

138.00

129.33

g/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.08

0.09

12.0

3.2

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.77

0.08

1.6

1.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.90

0.07

1.4

2.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

450

0.95

0.04

3.0

3.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

188

0.94

0.02

7.4

3.3

—

(40768804) Tissue Pathology biopsy report

242

1.05

0.02

2.4

1.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

154

1.05

0.00

4.2

4.3

18.27

23.36

—

(3026008) Bacteria identified in Urine by Culture

196

1.03

0.00

4.6

2.9

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

2.4

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.5

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.6

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.3

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

18.54

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

323.71

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.4

—

(4281824)

0.00

0.0

1.0

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.94

0.00

7.0

7.2

—

(3006462) Nitrate [Presence] in Urine

0.00

0.0

1.4

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.0

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

3.6

—

877.00

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

0.0

1.4

—

114.40

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

0.0

13.8

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

1.2

—

(3011648) Oxygen content in Venous blood

0.00

0.0

3.0

—

11.07

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.7

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

1.9

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.0

—

6.59

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(4211845)

0.00

0.0

1.3

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

0.0

1.6

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

2.2

—

4.04

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.2

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.0

3.7

—

61.67

—

(4146454)

0.00

0.0

3.9

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.98

0.00

1.4

2.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

3.4

—

20.22

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.9

—

2.16

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.1

—

194.19

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_OTHER_EFFEC_REDUCED_TEMPE – Other effects of reduced temperature

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Other effects of reduced temperature

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Other effects of reduced temperature (ST19_OTHER_EFFEC_REDUCED_TEMPE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints