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Wet age-related macular degeneration, under 50

WET_AMD_EARLY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE<50

Registry filters:

  • Hospital discharge: ICD-10 H35.31
  • Hospital discharge: ICD-9 3625B
  • Cause of death: ICD-10 H35.31
  • Cause of death: ICD-9 3625B

2 out of 7 registries used, show all original rules.

122

4. Check minimum number of events

None

122

5. Include endpoints

None

122

6. Filter based on genotype QC (FinnGen only)

115

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF12
Parent code in ICD-10
H35
Name in latin
Degeneratio maculae senilis exsudativa

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 115 60 55
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 41.92 40.92 43.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
122
Matched controls
1220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
12278.3
164.8
120
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
34.0
81.4
62
36
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
50.8
81.3
51
17
XCK10
NOMESCO Finland
Photography of fundus of eye
29.7
76.5
62
41
XCW99
NOMESCO Finland
Other investigative procedure of eye
25.0
69.3
61
47
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
137.5
61.5
62
9
CKC12
NOMESCO Finland
Photocoagulation of retina
25.6
50.3
39
22
Z01.0
ICD-10 Finland
Examination of eyes and vision
12.0
42.7
62
97
XCD20
NOMESCO Finland
Photoangiography of eye
77.8
34.7
38
7
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
121.1
33.8
35
*
A10AC01
ATC
insulin (human); parenteral
11.4
28.1
34
40
A10AE05
ATC
insulin detemir; parenteral
13.8
28.0
29
27
A10AB05
ATC
insulin aspart; parenteral
10.8
25.6
32
39
A10AB01
ATC
insulin (human); parenteral
12.2
25.1
28
29
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
155.6
24.6
25
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
54.3
22.5
26
6
XCH00
NOMESCO Finland
Eye pressure measurement
42.7
22.2
27
8
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
10.2
21.4
27
33
H36.01
ICD-10 Finland
Diabetic maculopathy
44.3
20.8
25
7
H43.1
ICD-10 Finland
Vitreous haemorrhage
88.5
20.4
22
*
T89
ICPC
Diabetes insulin dependent
10.2
20.0
25
30
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
6.9
17.5
32
60
H3603, E103,
ICD-10 Finland
74.2
17.3
19
*
ZXA10
NOMESCO Finland
Bilateral
5.7
17.2
41
99
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
195.6
16.9
17
*
A10AE04
ATC
insulin glargine; parenteral
7.1
16.8
29
51
H35.7
ICD-10 Finland
Separation of retinal layers
31.3
16.2
21
8
103
Kela drug reimbursment
Diabetes, insulin-treated
4.9
15.7
48
142
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
19.9
15.5
23
14
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
12.9
14.6
26
25
215
Kela drug reimbursment
Diabetes, non-insulin-treated
4.6
14.3
46
141
A10AA01, ,
ATC
11.5
13.8
26
28
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
13.8
13
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
11.3
13.3
25
27
A10AA02, ,
ATC
11.3
13.3
25
27
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
12.2
13.2
24
24
H36.00
ICD-10 Finland
Diabetic background retinopathy
36.4
12.9
16
5
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
+∞
12.7
12
*
H25.1
ICD-10 Finland
Senile nuclear cataract
6.7
12.5
22
39
TCK00
NOMESCO Finland
Photosensitisation of choroid and retina
+∞
11.6
11
*
H35.9
ICD-10 Finland
Retinal disorder, unspecified
48.1
11.2
13
*
H3601, E103,
ICD-10 Finland
24.2
11.0
15
7
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
65.9
10.8
12
*
S01ED51
ATC
timolol, combinations; ophthalmic
11.2
10.8
20
21
A10AE06
ATC
insulin degludec; parenteral
10.6
10.5
20
22
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
26.1
10.5
14
6
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.7
10.4
45
166
ZXA05
NOMESCO Finland
Left side
3.9
10.3
40
137
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
44.0
10.2
12
*
H04AA01
ATC
glucagon; nasal, parenteral
11.5
9.9
18
18
S01EC01
ATC
acetazolamide; systemic
19.5
9.7
14
8
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
32.9
9.6
12
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
32.9
9.6
12
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
24.0
9.6
13
6
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
108.1
9.6
10
*
B05DB
ATC
Hypertonic solutions
+∞
9.5
9
*
H3600, E103,
ICD-10 Finland
17.4
9.3
14
9
A10AB04
ATC
insulin lispro; parenteral
9.2
9.3
19
24
Z94.0
ICD-10 Finland
Kidney transplant status
39.9
9.2
11
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
26.4
9.1
12
5
CJB10
NOMESCO Finland
Laser discission of secondary cataract
13.0
8.8
15
13
A11CC03
ATC
alfacalcidol; systemic
54.0
8.8
10
*
Z3229
NOMESCO Finland
Other healthcare associate professional
5.3
8.7
19
41
H26.4
ICD-10 Finland
After-cataract
12.0
8.6
15
14
C03CA01
ATC
furosemide; systemic
4.0
8.6
28
84
Z49.0
ICD-10 Finland
Preparatory care for dialysis
96.4
8.5
9
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
9.2
8.4
17
21
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
18.8
8.3
12
7
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
36.0
8.2
10
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
36.0
8.2
10
*
127
Kela drug reimbursment
Transplant complication
23.9
8.2
11
5
205
Kela drug reimbursment
Chronic hypertension
4.0
7.9
26
78
B05DA
ATC
Isotonic solutions
48.1
7.8
9
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
48.1
7.8
9
*
L04AA06
ATC
mycophenolic acid; systemic
19.9
7.8
11
6
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
27.0
7.7
10
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
27.0
7.7
10
*
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
14.6
7.6
12
9
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
85.0
7.5
8
*
CA1ME
NOMESCO Finland
Ultrasound oculometry
85.0
7.5
8
*
H3601, E106,
ICD-10 Finland
85.0
7.5
8
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
85.0
7.5
8
*
H35.6
ICD-10 Finland
Retinal haemorrhage
85.0
7.5
8
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
8.2
7.5
16
22
H3603, E113,
ICD-10 Finland
+∞
7.4
7
*
137
Kela drug reimbursment
Uraemia requiring dialysis
32.1
7.3
9
*
C09AA02
ATC
enalapril; systemic
4.2
7.1
21
58
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
42.5
6.8
8
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
73.5
6.5
7
*
Z49.2
ICD-10 Finland
Other dialysis
73.5
6.5
7
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.8
6.4
14
20
WX402
NOMESCO Finland
General anaesthesia
3.0
6.4
34
138
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
19.2
6.4
9
5
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
+∞
6.3
6
*
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
6.3
6
*
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
9.4
6.2
12
14
S01BC03
ATC
diclofenac; ophthalmic
13.5
6.2
10
8
SPAT1262
SPAT
Handing over of treatment supplies
3.4
6.1
25
87

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
206
3.30
9.05
8.1
3.2
219.95
666.35
mg/l
0.50
36
148
49
216
3.12
8.24
9.9
3.9
44.81
9.59
mg/mmol
0.92
40
151
52
247
2.93
7.54
7.8
3.0
7.45
8.81
mmol/l
0.91
45
223
6
0
+∞
6.30
5.5
0.0
18.82
—
mmol/l
—
6
0
6
0
+∞
6.30
5.7
0.0
512.67
—
umol/l
—
6
0
25
93
3.12
5.41
1.6
1.5
1193.79
1225.51
nmol/l
0.06
20
74
20
65
3.48
5.35
15.3
3.1
—
—
—
0
0
27
107
2.96
5.24
2.4
2.7
—
—
—
0
0
15
41
4.03
5.10
7.1
4.6
20.33
24.86
mmol/l
1.65
15
41
19
63
3.39
4.92
15.3
2.8
5.69
5.79
kpa
0.16
19
63
19
63
3.39
4.92
7.7
3.3
1.69
1.83
%
0.25
19
58
51
287
2.34
4.82
1.8
1.7
94.12
100.10
pmol/l
0.27
24
156
10
14
7.67
4.75
3.9
3.3
—
—
—
0
0
18
60
3.35
4.62
18.7
7.0
—
—
—
0
0
23
91
2.88
4.45
7.9
1.9
21.59
25.41
%
0.78
18
78
8
10
8.46
4.13
1.1
1.2
—
—
—
0
0
8
10
8.46
4.13
2.3
2.5
—
—
—
0
0
14
37
4.14
4.05
1.9
1.3
—
—
—
0
0
6
5
12.52
3.80
1.5
1.2
—
—
—
0
0
15
52
3.15
3.61
5.1
2.1
5.06
4.44
kpa
0.76
15
52
11
27
4.37
3.49
9.0
1.8
21.91
24.84
mmol/l
1.54
11
27
20
85
2.62
3.36
1.5
1.9
404.20
360.40
nmol/l
0.61
20
80
10
24
4.44
3.27
1.1
1.3
—
—
—
0
0
41
242
2.05
3.23
1.4
1.3
5.56
0.72
u/ml
0.52
14
66
10
25
4.26
3.16
3.4
1.3
—
—
—
0
0
8
16
5.27
3.10
3.0
2.4
24.99
25.95
mmol/l
—
8
16
6
8
7.81
3.09
1.2
1.0
98.00
70.13
mmol/l
—
6
8
18
76
2.61
3.06
15.1
14.6
4.93
5.15
kpa
0.51
18
69
13
46
3.04
3.02
4.6
3.5
115.38
134.50
g/l
1.36
13
46
49
317
1.91
2.93
13.7
8.9
1.18
1.15
inr
0.09
11
95
8
205
0.35
2.76
1.5
1.4
—
—
—
0
0
16
68
2.56
2.69
16.1
16.1
95.65
96.24
%
0.16
16
61
60
424
1.82
2.66
5.9
2.6
90.22
99.93
ug/l
0.31
60
400
32
185
1.99
2.62
3.5
3.0
—
—
—
0
0
61
435
1.80
2.61
11.7
8.3
0.00
0.00
e9/l
0.50
52
348
15
63
2.57
2.58
16.7
17.0
110.07
127.54
g/l
1.63
15
57
21
104
2.23
2.55
2.2
1.6
—
—
—
0
0
32
188
1.95
2.50
2.3
1.7
1.20
0.63
mg/l
0.71
23
143
11
38
3.08
2.49
17.5
3.4
23.49
24.42
mmol/l
0.50
11
38
12
46
2.78
2.44
2.5
2.0
619.43
2098.84
u/l
—
5
18
17
79
2.34
2.38
2.6
2.5
9.32
10.84
g/l
0.94
17
72
12
47
2.72
2.35
2.2
4.0
67.30
68.99
g/l
0.24
12
47
10
34
3.11
2.34
17.0
23.6
—
—
—
0
0
30
178
1.91
2.26
4.2
4.6
—
—
—
0
0
8
24
3.49
2.22
1.3
1.2
—
—
—
0
0
35
221
1.82
2.18
1.5
1.3
2.34
2.42
g/l
0.11
25
140
43
290
1.75
2.14
2.6
2.7
23.28
22.70
ng/l
0.02
26
142
21
113
2.04
2.07
1.6
1.7
—
—
—
0
0
30
183
1.85
2.07
1.9
1.7
—
—
—
0
0
67
514
1.67
2.06
8.8
6.0
2.61
1.87
e9/l
0.38
62
469
51
366
1.68
2.01
26.2
8.0
1.20
1.21
mmol/l
0.33
46
316
5
11
4.69
1.96
3.0
2.6
—
—
—
0
0
34
220
1.76
1.93
8.9
3.9
7.41
7.41
ph
—
8
39
63
481
1.64
1.93
9.1
5.6
60.09
56.92
%
1.23
57
460
5
12
4.29
1.84
3.2
2.6
8.46
8.41
kpa
—
5
12
35
234
1.70
1.76
8.4
7.4
—
—
—
0
0
11
48
2.42
1.76
1.7
1.6
406.73
321.05
mu/l
0.53
11
43
66
518
1.60
1.76
9.0
6.4
0.19
0.19
e9/l
0.02
60
471
104
918
1.90
1.74
5.0
4.3
1.75
1.78
mu/l
0.09
97
875
5
13
3.96
1.73
4.8
1.4
67.60
64.95
%
—
5
13
64
501
1.58
1.71
8.7
6.0
0.58
0.56
e9/l
0.29
59
452
64
501
1.58
1.71
8.7
6.1
0.04
0.04
e9/l
0.27
59
452
10
43
2.44
1.63
19.8
10.4
0.76
0.68
%
—
10
43
10
44
2.38
1.60
19.0
10.2
1.66
1.80
%
—
10
44
51
384
1.56
1.58
5.0
2.6
6.20
5.67
ph
—
5
50
26
165
1.73
1.57
1.8
1.4
27.62
22.07
nmol/l
0.71
26
147
0
43
0.00
1.55
0.0
7.8
—
—
—
0
0
9
37
2.54
1.51
4.1
1.7
—
—
—
0
0
10
45
2.33
1.51
19.7
10.1
94.25
93.87
%
—
10
45
9
38
2.48
1.49
3.7
2.1
0.68
0.72
%
—
9
38
88
756
1.59
1.47
4.3
3.8
14.53
14.59
pmol/l
0.08
82
719
6
22
2.81
1.45
11.8
25.6
1.48
1.27
mmol/l
—
6
15
18
105
1.84
1.42
1.6
1.6
—
—
—
0
0
5
17
3.02
1.37
1.0
1.0
—
—
—
0
0
29
198
1.61
1.33
3.7
2.1
—
—
—
0
0
22
140
1.70
1.32
3.7
2.5
169.47
78.99
ug/g
0.85
17
110
5
18
2.85
1.30
2.8
2.1
—
—
—
0
0
6
25
2.47
1.26
11.3
25.2
0.80
0.92
%
—
6
19
23
151
1.64
1.23
8.8
2.4
4.50
3.97
e6/l
0.13
23
135
38
282
1.50
1.21
10.0
3.1
5.99
109.09
e6/l
0.52
26
187
6
26
2.37
1.20
11.3
24.5
1.10
1.39
%
—
6
19
35
257
1.51
1.17
1.7
1.7
1.47
1.49
mmol/l
0.05
29
226
5
20
2.56
1.16
1.6
1.6
75.40
49.33
pmol/l
—
5
20
68
577
1.40
1.04
11.3
10.3
4.59
3.99
e9/l
1.10
63
507
38
291
1.44
1.03
1.5
1.4
—
—
—
0
0
31
229
1.47
1.00
2.0
1.7
—
—
—
0
0
7
36
2.00
0.99
2.6
3.8
—
—
—
0
0
6
27
2.28
0.95
1.8
1.2
—
—
—
0
0
28
205
1.47
0.95
8.5
2.5
0.21
0.30
e6/l
0.30
23
146
55
456
1.38
0.94
5.5
2.8
0.00
0.01
estimate
—
9
82
6
28
2.20
0.93
1.2
1.5
0.21
0.25
g/l
—
6
28
6
29
2.12
0.90
1.2
1.5
1.13
1.17
g/l
—
6
29
99
908
1.48
0.90
21.3
13.1
14.52
14.23
%
0.22
99
899
8
43
1.92
0.89
13.1
16.0
—
—
—
0
0
8
43
1.92
0.89
1.8
3.4
14.62
39.59
u/ml
—
8
43
6
30
2.05
0.88
1.2
1.1
—
—
—
0
0
21
147
1.52
0.87
4.7
2.9
22.20
205.92
ng/l
1.23
15
84
17
114
1.57
0.85
1.2
1.2
—
—
—
0
0
71
621
1.34
0.83
8.2
3.3
—
—
—
0
0
10
58
1.79
0.82
1.0
1.3
137.40
596.50
u/ml
—
10
48
11
66
1.73
0.82
25.0
3.9
—
—
—
0
0
21
150
1.48
0.80
2.2
1.9
—
—
—
0
0
28
212
1.42
0.80
6.3
2.5
—
—
—
0
0
0
25
0.00
0.80
0.0
1.8
—
—
—
0
0
9
53
1.75
0.77
4.4
2.2
—
—
—
0
0
116
1111
1.90
0.76
14.8
8.9
28.23
30.02
u/l
0.57
116
1091
53
450
1.31
0.74
8.7
3.9
0.00
0.00
estimate
—
9
78
5
25
2.04
0.73
1.0
1.0
—
—
—
0
0
7
118
0.57
0.72
1.1
1.4
—
—
—
0
0
5
26
1.96
0.71
1.6
1.8
9.66
1.16
ug/l
—
5
26
103
967
1.42
0.66
5.5
3.6
6.75
5.75
mmol/l
3.03
97
912
13
87
1.55
0.66
19.2
7.6
104.92
104.47
mmol/l
0.09
13
87
5
29
1.75
0.64
1.2
1.6
—
—
—
0
0
53
457
1.28
0.64
5.7
2.9
0.00
0.00
estimate
—
9
73
36
297
1.30
0.60
9.7
2.6
53.83
54.14
u/l
0.02
36
276
19
143
1.39
0.57
7.5
2.3
538.32
581.41
mosm/kgh2o
0.36
19
125
15
109
1.43
0.54
1.4
1.3
—
—
—
0
0
10
67
1.54
0.51
8.4
3.2
—
—
—
0
0
54
477
1.24
0.51
10.3
6.4
—
—
—
0
0
107
1022
1.38
0.50
20.8
10.7
20.94
19.33
mg/l
0.19
82
771
33
277
1.26
0.48
2.9
2.1
—
—
—
0
0
22
175
1.31
0.47
1.5
1.3
19.00
23.26
iu/ml
—
6
58
32
268
1.26
0.47
3.4
2.0
—
—
—
0
0
5
82
0.59
0.47
1.0
1.6
—
—
—
0
0
12
87
1.42
0.44
1.3
1.1
—
—
—
0
0
26
216
1.26
0.41
5.4
3.2
0.00
0.00
estimate
—
7
78
0
16
0.00
0.41
0.0
3.8
—
23.37
—
0
16
106
1096
0.75
0.41
15.2
9.5
—
—
—
0
0
8
60
1.36
0.41
1.4
1.4
—
283.91
—
0
33
0
18
0.00
0.40
0.0
18.3
—
1300.61
—
0
18
0
18
0.00
0.40
0.0
14.8
—
827.22
—
0
18
5
36
1.41
0.38
4.0
1.9
—
—
—
0
0
41
362
1.20
0.37
2.0
1.8
—
—
—
0
0
70
650
1.18
0.36
3.1
2.9
—
—
—
0
0
6
43
1.42
0.35
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
222.42
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.13
—
0
5
20
174
1.18
0.21
1.4
1.2
1.10
5.84
u/ml
—
6
77
7
62
1.14
0.17
1.0
1.1
—
—
—
0
0
30
274
1.13
0.17
6.2
2.4
—
—
—
0
0
5
69
0.71
0.17
1.4
3.0
4.30
4.71
pmol/l
—
5
58
102
997
1.14
0.16
5.3
3.5
1.33
1.34
mmol/l
0.04
96
946
117
1173
0.94
0.09
28.8
15.7
4.55
4.65
e12/l
1.21
117
1147
117
1173
0.94
0.09
28.7
15.6
89.50
90.23
fl
1.02
117
1160
117
1173
0.94
0.09
29.0
15.7
135.22
140.03
g/l
2.47
117
1159
117
1173
0.94
0.09
28.8
15.8
7.27
6.55
e9/l
0.80
117
1147
117
1172
0.96
0.09
28.7
15.6
29.90
30.22
pg
1.23
117
1159
14
126
1.13
0.09
2.1
1.7
—
—
—
0
0
5
64
0.77
0.08
1.4
1.1
—
—
—
0
0
15
164
0.90
0.08
1.4
1.4
—
—
—
0
0
7
68
1.03
0.08
2.0
1.2
—
—
—
0
0
9
103
0.86
0.06
1.0
1.2
—
—
—
0
0
48
466
1.05
0.06
3.5
2.5
—
—
—
0
0
23
219
1.06
0.04
3.7
2.5
—
—
—
0
0
15
153
0.98
0.00
1.1
2.2
1.02
0.72
ug/l
—
6
72
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
117
1170
1.00
-0.00
28.9
15.7
258.91
256.44
e9/l
0.15
117
1147
0
6
0.00
-0.00
0.0
1.8
—
16.93
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
34.43
—
0
7
0
7
0.00
-0.00
0.0
1.7
—
0.89
—
0
7
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
87.95
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
7.52
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
181.33
—
0
8
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
7
69
1.02
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
6.68
—
0
6
10
100
1.00
-0.00
1.5
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
27.40
—
0
5
0
7
0.00
-0.00
0.0
2.0
—
1.60
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
22.99
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
1.43
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: WET_AMD_EARLY – Wet age-related macular degeneration, under 50

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).