toxoplasmosis: A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpoints |
953 |
6. Filter based on genotype QC (FinnGen only) |
953 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
Protozoal diseases
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6426 | 2933 | 3386 |
| Only index persons | 5431 | 2564 | 2867 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.08 | 0.09 |
| Only index persons | 0.10 | 0.09 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 46.07 | 44.91 | 47.33 |
| Only index persons | 44.50 | 43.08 | 45.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 953 | 479 | 474 |
| Unadjusted period prevalence (%) | 0.19 | 0.16 | 0.21 |
| Median age at first event (years) | 55.17 | 50.84 | 59.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 830
- Matched controls
- 8298
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
+∞
323.0
367
*
TGC00
NOMESCO Finland
Bronchial lavation
36.3
165.4
215
79
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
12.3
118.4
231
253
UGC12
NOMESCO Finland
Flexible bronchoscopy
10.2
110.2
239
317
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
13.9
101.4
183
165
B59
ICD-10 Finland
Pneumocystosis
+∞
99.0
93
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
12.2
97.1
187
193
R50.9
ICD-10 Finland
Fever, unspecified
6.3
92.2
291
659
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.0
89.8
375
1171
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.7
68.9
525
2636
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.9
67.8
213
457
XW000
NOMESCO Finland
Bone marrow biopsy
9.8
62.1
132
157
H32.0*B58.0
ICD-10 Finland
Toxoplasma chorioretinitis
+∞
61.2
58
*
ZX108
NOMESCO Finland
Inhalation
39.7
60.3
76
21
B50.9
ICD-10 Finland
Plasmodium falciparum malaria, unspecified
+∞
54.8
52
*
JN4BD
NOMESCO Finland
Extensive body CT
4.8
53.9
203
522
H02AB06
ATC
prednisolone; systemic
3.1
52.5
514
2851
L03AA02
ATC
filgrastim; parenteral
10.7
50.5
101
106
ZX120
NOMESCO Finland
Intravenous
4.8
47.0
173
428
JN4AD
NOMESCO Finland
Body CT examination
5.3
46.0
153
338
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
8.0
46.0
109
153
WW500
NOMESCO Finland
Blood transfusion
8.1
45.9
108
150
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.3
45.8
116
180
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.6
45.1
174
451
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
9.4
42.9
92
109
B54
ICD-10 Finland
Unspecified malaria
+∞
42.0
40
*
A03FA01
ATC
metoclopramide; systemic, rectal
3.3
41.3
263
1034
A04AA01
ATC
ondansetron; systemic, rectal
5.3
38.2
124
264
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
37.3
350
1753
M04AA01
ATC
allopurinol; systemic
3.7
36.3
181
584
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.8
36.2
130
308
L04AA06
ATC
mycophenolic acid; systemic
12.5
36.2
66
57
J01FF01
ATC
clindamycin; systemic
2.7
36.0
321
1552
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
11.7
35.6
67
62
127
Kela drug reimbursment
Transplant complication
14.6
35.3
60
44
L03AA13
ATC
pegfilgrastim; parenteral
7.0
34.1
88
139
D70.82
ICD-10 Finland
Drug-induced neutropenia
14.1
33.7
58
44
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
10.1
33.4
68
73
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.8
32.5
117
277
H02AB02
ATC
dexamethasone; systemic
3.7
31.8
154
480
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.3
31.5
87
151
Z51.5
ICD-10 Finland
Palliative care
5.2
31.3
102
216
J01MA12
ATC
levofloxacin; systemic
2.9
31.3
226
942
GD1AD
NOMESCO Finland
Thorax CT examination
6.0
31.3
90
164
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
12.4
31.3
57
49
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.0
31.2
80
125
J01MA14
ATC
moxifloxacin; systemic
4.1
31.0
132
368
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
30.9
173
604
J05AB11
ATC
valaciclovir; oral
3.4
30.7
169
583
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
13.8
30.0
52
40
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
29.4
194
757
B58.9
ICD-10 Finland
Toxoplasmosis, unspecified
+∞
28.3
27
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.6
27.8
103
250
L04AX01
ATC
azathioprine; systemic
5.5
27.2
83
163
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
14.9
26.4
44
31
13000
ICD-8 Finland
Toxoplasmosis, Acquired
+∞
26.2
25
*
A02BC02
ATC
pantoprazole; systemic
2.2
26.0
573
4134
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.4
24.7
60
87
WW200
NOMESCO Finland
Immunization
6.6
24.5
64
103
L04AD01
ATC
ciclosporin; systemic
8.8
24.4
53
64
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.0
24.2
61
93
C03CA01
ATC
furosemide; systemic
2.3
24.2
277
1461
A04AA02
ATC
granisetron; systemic, transdermal
4.3
24.1
95
244
D70.89
ICD-10 Finland
Neutropenic splenomegaly
15.7
24.0
39
26
1CX01
NOMESCO Finland
NA
48.2
23.4
28
6
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.6
23.3
112
343
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.2
23.2
92
238
N02AA05
ATC
oxycodone; systemic
2.8
22.6
164
671
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
14.8
22.3
37
26
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
22.1
22.3
32
15
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
13.7
22.1
38
29
L03AA14
ATC
lipegfilgrastim; parenteral
10.0
22.0
44
46
B58.0
ICD-10 Finland
Toxoplasma oculopathy
+∞
22.0
21
*
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
15.0
21.8
36
25
H02AB07
ATC
prednisone; oral
2.6
20.8
169
736
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
20.8
220
1102
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
16.3
20.7
33
21
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
8.3
20.2
45
57
R4110
NOMESCO Finland
Physiotherapy
2.2
20.0
263
1457
TK800
NOMESCO Finland
Hemodialysis
8.0
19.8
45
59
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
13.1
19.5
34
27
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.9
19.4
133
520
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
16.3
18.9
30
19
H32.0
ICD-10 Finland
Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
+∞
18.8
18
*
J05AB01
ATC
aciclovir; systemic
2.3
18.8
204
1029
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.0
18.6
306
1852
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
18.3
159
714
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
45.1
18.3
22
5
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
9.4
18.0
37
41
1302A
ICD-9 Finland
Toxoplasmosis, Chorioretinitis due to toxoplasmosis
+∞
17.8
17
*
ZX112
NOMESCO Finland
Subcutaneous
6.2
17.3
47
80
WF049
NOMESCO Finland
Radiotherapy of metastasis
5.3
17.3
53
105
H02AB04
ATC
methylprednisolone; systemic
2.5
17.2
152
687
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
17.9
17.0
26
15
A41.9
ICD-10 Finland
Sepsis, unspecified
4.8
16.8
57
126
13099
ICD-8 Finland
Toxoplasmosis, Unspecified
+∞
16.7
16
*
1XC02
NOMESCO Finland
NA
13.8
16.6
28
21
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.9
16.5
41
62
Z94.0
ICD-10 Finland
Kidney transplant status
11.5
16.3
30
27
D64.9
ICD-10 Finland
Anaemia, unspecified
2.9
16.3
106
401
WX892
NOMESCO Finland
Monitored bed care
3.1
16.1
92
320
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.7
16.0
32
34
B01AB10
ATC
tinzaparin; parenteral
3.3
16.0
83
269
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
15.9
267
1608
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
7.4
15.7
37
52
WW300
NOMESCO Finland
Transfer of autologic stem cells
19.7
15.6
23
12
L04AA01
ATC
[U] ciclosporin; systemic
7.6
15.6
36
49
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
15.6
167
830
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
15.4
101
383
Z49.1
ICD-10 Finland
Extracorporeal dialysis
9.2
15.1
31
35
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
9.7
15.0
30
32
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
15.0
95
353
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
32.4
14.8
19
6
0840A
ICD-9 Finland
Malaria, Falciparum malaria [malignant tertian]
+∞
14.6
14
*
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
14.6
14
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.5
14.5
69
209
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
6.0
14.5
40
70
A11CC03
ATC
alfacalcidol; systemic
5.8
14.2
40
72
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
14.2
162
825
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
12.2
14.1
25
21
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
11.7
13.9
25
22
L01AA02
ATC
chlorambucil; oral
54.3
13.8
16
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
20.5
13.8
20
10
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
13.6
100
406
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
7.6
13.5
31
42
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
34.7
13.5
17
5
WX726
NOMESCO Finland
High-flow oxygen therapy
142.2
13.5
14
*
J17.3
ICD-10 Finland
Pneumonia in parasitic diseases
142.2
13.5
14
*
JN6AD
NOMESCO Finland
CT of torso and neck
7.5
13.1
30
41
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
13.0
349
2426
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.2
13.0
49
122
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
13.3
13.0
22
17
B03XA02
ATC
darbepoetin alfa; parenteral
7.1
13.0
31
45
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.6
12.9
97
399
L01AA01
ATC
cyclophosphamide; systemic
23.0
12.9
18
8
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
8.2
12.9
28
35
M05BX04
ATC
denosumab; parenteral
3.7
12.8
56
159
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
12.6
95
391
A07EC01
ATC
sulfasalazine; oral, rectal
2.8
12.6
85
329
WF004
NOMESCO Finland
Palliative radiotherapy
5.8
12.5
35
63
6BA02
NOMESCO Finland
NA
24.7
12.5
17
7
J02AC03
ATC
voriconazole; systemic
24.7
12.5
17
7
R06.0
ICD-10 Finland
Dyspnoea
1.9
12.2
219
1329
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
27.1
12.1
16
6
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.6
12.0
91
374
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
11.9
102
452
A12AA04
ATC
calcium carbonate; oral
6.8
11.8
29
44
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
9.8
11.8
23
24
B03XA01
ATC
erythropoietin; parenteral
8.8
11.6
24
28
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.5
11.5
40
92
WX002
NOMESCO Finland
Sedation and analgesia
1.9
11.5
185
1073
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
3.2
11.5
61
202
C90.0
ICD-10 Finland
Multiple myeloma
7.6
11.5
26
35
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.3
11.3
57
182
C83.1
ICD-10 Finland
Mantle cell lymphoma
17.3
11.2
17
10
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
12.9
11.2
19
15
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
25.4
11.2
15
6
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.3
11.2
41
100
A05AA02
ATC
ursodeoxycholic acid; oral
6.2
11.1
29
48
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
11.0
150
817
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.4
11.0
32
61
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
11.0
189
1126
J01MA02
ATC
ciprofloxacin; systemic
1.7
11.0
320
2250
L01BB05
ATC
fludarabine; systemic
43.9
10.9
13
*
H30.0
ICD-10 Finland
Focal chorioretinal inflammation
43.9
10.9
13
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
10.8
415
3140
WW409
NOMESCO Finland
Other aferesis
21.8
10.7
15
7
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
13.1
10.7
18
14
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.7
10.6
45
125
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.7
10.6
71
275
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
10.6
104
493
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
10.2
10.5
20
20
1309X
ICD-9 Finland
Toxoplasmosis, unspecified
+∞
10.4
10
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
3.9
10.3
42
113
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.0
10.1
58
203
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
2.8
10.1
63
233
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
10.1
157
899
P01BA02
ATC
hydroxychloroquine; oral
2.5
10.0
79
333
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.0
10.0
57
198
PJA10
NOMESCO Finland
Exploration of lymph nodes
7.8
9.9
22
29
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.0
9.9
57
200
B99
ICD-10 Finland
Other and unspecified infectious diseases
5.8
9.9
27
48
390
Kela drug reimbursment
Ibrutinib
26.4
9.8
13
5
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
26.4
9.8
13
5
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.0
9.8
38
98
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
3.6
9.8
43
124
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.5
9.7
44
130
A07AA02
ATC
nystatin; oral
2.6
9.6
68
271
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
6.5
9.6
24
38
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.9
9.6
57
205
XX3DW
NOMESCO Finland
Time consuming IT work
2.3
9.6
93
439
HA1AA
NOMESCO Finland
X-ray mammography
2.6
9.5
68
273
J01DB01
ATC
cefalexin; oral
1.7
9.5
658
5731
M05BA04
ATC
alendronic acid; oral
2.5
9.5
73
303
B01AB05
ATC
enoxaparin; parenteral
1.7
9.5
256
1743
08410
ICD-8 Finland
Vivax malaria (benign tertian)
+∞
9.4
9
*
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
22.0
9.4
13
6
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
9.3
102
507
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
4.9
9.2
29
61
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
13.9
9.2
15
11
WX720
NOMESCO Finland
Own respiration
3.2
9.2
47
153
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.0
9.1
24
41
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
9.1
221
1456
L01XE27
ATC
[U] ibrutinib; oral
37.1
9.0
11
*
TAB00
NOMESCO Finland
Lumbar puncture
3.0
9.0
51
176
N18.0
ICD-10 Finland
End-stage renal disease
7.6
9.0
20
27
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.6
8.9
67
276
H02AB09
ATC
hydrocortisone; systemic
4.0
8.9
34
87
ZX090
NOMESCO Finland
Other technic of radiotherapy
3.9
8.9
35
92
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
8.9
70
297
A07AA09
ATC
vancomycin; oral
6.9
8.9
21
31
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
7.3
8.8
20
28
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
14.2
8.7
14
10
J96.0
ICD-10 Finland
Acute respiratory failure
7.8
8.7
19
25
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.7
8.7
28
61
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
16.5
8.6
13
8
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
8.6
95
475
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
27.8
8.5
11
*
B20.6
ICD-10 Finland
HIV disease resulting in Pneumocystis jirovecii pneumonia
90.9
8.4
9
*
A04AA55
ATC
palonosetron, combinations; systemic
3.9
8.4
33
87
WZC30
NOMESCO Finland
Teaching
2.0
8.4
112
606
B55.1
ICD-10 Finland
Cutaneous leishmaniasis
+∞
8.3
8
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
8.3
133
766
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
10.9
8.3
15
14
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
8.2
228
1555
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.1
8.1
30
75
RD210
NOMESCO Finland
NA
4.5
8.1
27
61
Z94.2
ICD-10 Finland
Lung transplant status
33.7
8.1
10
*
J12.8
ICD-10 Finland
Other viral pneumonia
9.0
8.1
16
18
1512
Kela drug reimbursment
Ibrutinib
22.3
8.0
11
5
B02.9
ICD-10 Finland
Zoster without complication
2.5
8.0
61
253
C82.1
ICD-10 Finland
Follicular lymphoma grade II
7.3
8.0
18
25
137
Kela drug reimbursment
Uraemia requiring dialysis
7.3
8.0
18
25
N18.8
ICD-10 Finland
Other chronic renal failure
3.8
7.9
32
87
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.7
7.9
19
29
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
13.2
7.9
13
10
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
5.8
7.9
21
37
N05CF01
ATC
zopiclone; oral
1.6
7.9
247
1735
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
7.8
321
2407
A04AD12
ATC
aprepitant; systemic
4.5
7.8
26
59
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.4
7.7
22
42
ZXA00
NOMESCO Finland
Right side
1.6
7.7
224
1543
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.3
7.7
27
65
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
7.6
67
299
YNB10
NOMESCO Finland
Collection of stem cells for transplant
18.6
7.6
11
6
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
18.6
7.6
11
6
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
12.0
7.6
13
11
A46
ICD-10 Finland
Erysipelas
1.9
7.5
118
675
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.9
7.5
44
158
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
7.5
87
444
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.3
7.4
69
319
WX110
NOMESCO Finland
Local anesthesy
1.5
7.3
535
4532
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
8.5
7.3
15
18
R4190
NOMESCO Finland
Nutritional therapy
3.2
7.3
37
121
B51.9
ICD-10 Finland
Plasmodium vivax malaria without complication
+∞
7.3
7
*
B50.0
ICD-10 Finland
Plasmodium falciparum malaria with cerebral complications
+∞
7.3
7
*
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
7.4
7.2
16
22
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.2
188
1256
E0000UV
ATC
NA
1.5
7.2
295
2203
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
30.3
7.2
9
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
30.3
7.2
9
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.6
7.1
23
51
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
6.1
7.1
18
30
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
7.1
171
1118
RS220
NOMESCO Finland
NA
5.2
7.0
20
39
NH3EA
NOMESCO Finland
Feet X-ray examination with load
4.1
6.9
25
62
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.2
6.9
67
315
SPAT1255
SPAT
Intravenous administration of medicine
2.4
6.8
57
251
WX882
NOMESCO Finland
High dependency care
3.4
6.8
31
94
M31.3
ICD-10 Finland
Wegener granulomatosis
11.0
6.8
12
11
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
5.7
6.8
18
32
GDG10
NOMESCO Finland
Bilateral transplantation of lung
40.4
6.8
8
*
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
16.8
6.8
10
6
TQW99
NOMESCO Finland
Other minor procedure on skin
2.6
6.7
47
188
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.1
6.7
34
112
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.0
6.7
20
41
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
6.5
6.7
16
25
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
6.6
97
542
ZXA05
NOMESCO Finland
Left side
1.6
6.6
197
1360
JN4CD
NOMESCO Finland
Very extensive body CT
2.7
6.6
42
158
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
6.6
130
800
L02BG06
ATC
exemestane; oral
5.4
6.5
18
34
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.3
6.5
57
257
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
6.5
58
266
N19
ICD-10 Finland
Unspecified kidney failure
3.2
6.4
32
104
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
70.4
6.4
7
*
H30.2
ICD-10 Finland
Posterior cyclitis
70.4
6.4
7
*
399
Kela drug reimbursment
Venetoclax
70.4
6.4
7
*
1518
Kela drug reimbursment
NA
70.4
6.4
7
*
L01XX52
ATC
venetoclax; oral
70.4
6.4
7
*
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
7.5
6.4
14
19
DHA10
NOMESCO Finland
Biopsy of cavity of nose
6.6
6.4
15
23
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.6
6.3
42
164
WX725
NOMESCO Finland
Noninvasive ventilation
2.5
6.3
45
183
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
11.1
6.3
11
10
D69.5
ICD-10 Finland
Secondary thrombocytopenia
11.1
6.3
11
10
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
6.3
56
255
0846X
ICD-9 Finland
Malaria, unspecified
+∞
6.3
6
*
08400
ICD-8 Finland
Falicparum malaria (malignant tertian)
+∞
6.3
6
*
08499
ICD-8 Finland
Malaria, Unspecified forms
+∞
6.3
6
*
B60.8
ICD-10 Finland
Other specified protozoal diseases
+∞
6.3
6
*
B53.0
ICD-10 Finland
Plasmodium ovale malaria
+∞
6.3
6
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
6.3
6
*
9680/3-C77.8
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph nodes of multiple regions
26.9
6.2
8
*
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.4
6.2
28
85
R2110
NOMESCO Finland
Giving the first information
2.2
6.2
58
270
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
12.6
6.1
10
8
EBA10
NOMESCO Finland
Surgical removal of tooth
1.9
6.1
87
483
P01AB01
ATC
metronidazole; oral, rectal
1.5
6.1
293
2247
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
6.1
160
1069
R81
ICPC
Pneumonia
3.0
6.1
32
109
H26.3
ICD-10 Finland
Drug-induced cataract
8.7
6.1
12
14
284
Kela drug reimbursment
Nintedanib and pirfenidone
10.1
6.0
11
11
R03AC02
ATC
salbutamol; inhalant
1.4
6.0
404
3304
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
257
165
20.96
310.37
7.5
6.2
366.4
394.9
iu/ml
0.06
49
22
249
151
21.97
309.00
2.2
1.6
—
—
—
0
0
342
81
65.30
307.65
2.0
1.7
—
—
—
0
0
265
200
17.97
293.66
2.9
1.7
—
—
—
0
0
263
198
17.96
291.76
3.0
1.7
—
—
—
0
0
221
119
23.88
288.75
2.1
1.6
—
—
—
0
0
223
148
19.36
263.27
2.9
1.8
—
—
—
0
0
273
283
13.12
247.47
3.3
2.8
—
—
—
0
0
194
114
21.11
242.35
2.5
1.7
—
—
—
0
0
189
116
20.08
230.95
2.3
1.6
—
—
—
0
0
191
130
18.12
221.34
2.3
1.5
—
—
—
0
0
135
38
41.22
219.45
1.3
1.5
—
—
—
0
0
180
133
16.45
198.99
3.9
3.2
932.9
2245.6
u/ml
0.35
15
13
202
182
13.82
198.69
1.9
1.5
—
—
—
0
0
155
91
20.15
192.54
2.6
1.8
—
—
—
0
0
127
65
22.39
167.30
3.4
2.1
471.3
769.5
e6/l
1.43
39
23
99
24
45.92
166.34
1.4
1.3
—
—
—
0
0
118
52
25.76
165.14
2.4
1.8
12.7
12.2
%
0.09
44
28
119
61
22.15
156.46
3.8
2.8
33.8
42.0
%
1.01
32
18
113
52
24.52
155.32
2.6
1.9
—
—
—
0
0
361
920
5.71
140.67
3.4
1.8
—
—
—
0
0
126
91
15.80
139.83
2.9
1.8
—
—
—
0
0
121
83
16.55
138.04
3.0
1.8
—
—
—
0
0
429
1291
5.22
136.83
3.9
1.9
—
—
—
0
0
350
914
5.47
131.57
3.2
1.8
—
—
—
0
0
285
642
5.91
126.14
6.7
2.7
8.2
10.7
g/l
12.83
277
592
340
912
5.24
122.86
10.8
4.4
260.8
258.1
u/l
0.09
329
869
89
52
18.78
109.64
2.6
1.7
—
—
—
0
0
83
44
20.57
106.88
2.7
1.7
—
—
—
0
0
82
45
19.84
103.92
2.8
1.7
—
—
—
0
0
65
19
36.64
103.39
2.1
1.7
—
—
—
0
0
87
55
17.31
103.02
3.5
1.9
509.9
635.8
e6/l
0.33
79
45
71
37
20.65
91.93
1.9
2.1
142629.3
88880.8
u/ml
—
16
5
332
1080
4.18
90.14
13.8
5.9
1.1
1.0
mmol/l
0.79
323
998
84
66
13.86
88.14
2.9
1.7
—
—
—
0
0
171
330
6.10
87.39
3.1
2.0
1.0
2.3
ug/l
0.74
157
295
88
77
12.49
86.44
1.5
1.3
—
—
—
0
0
87
78
12.17
84.10
3.1
1.7
—
—
—
0
0
87
78
12.17
84.10
3.1
1.7
—
—
—
0
0
87
78
12.17
84.10
3.1
1.7
—
—
—
0
0
225
592
4.67
80.09
2.7
1.6
—
—
—
0
0
169
352
5.62
79.25
2.8
1.6
9.7
11.7
u/ml
0.17
12
12
360
1337
3.72
79.18
7.6
3.6
0.8
0.8
mmol/l
0.86
346
1248
683
3829
3.77
77.19
18.3
6.0
26.3
27.7
%
1.76
666
3571
675
3770
3.71
76.41
16.8
5.8
58.9
57.2
%
2.35
659
3534
46
13
37.13
73.51
1.8
2.0
—
—
—
0
0
104
157
7.31
67.04
1.5
1.4
88.9
103.3
u/ml
0.56
15
28
77
82
10.13
65.93
3.5
3.9
—
—
—
0
0
86
109
8.57
64.39
1.3
1.1
—
—
—
0
0
41
13
32.91
63.28
1.1
1.4
—
—
—
0
0
732
4626
3.51
61.24
30.5
9.3
4.2
4.1
e9/l
0.38
685
4055
102
166
6.76
61.18
1.3
1.3
—
—
—
0
0
153
364
4.82
60.82
2.6
2.1
1.5
1.5
g/l
0.13
129
318
122
239
5.71
60.60
1.8
1.7
—
—
—
0
0
55
47
12.36
54.50
1.6
1.2
—
—
—
0
0
587
3404
2.89
54.48
11.9
5.1
33.6
35.5
g/l
9.91
559
3179
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
119
253
5.23
53.80
3.8
2.6
0.4
0.3
u/ml
0.35
79
148
93
159
6.37
53.03
1.3
1.3
268.1
264.2
u/ml
0.04
64
98
42
24
18.26
51.77
3.9
1.9
—
—
—
0
0
364
1703
2.84
50.09
4.3
2.5
4.7
5.5
e6/l
0.51
344
1504
660
4197
2.86
49.16
17.7
6.6
10.4
11.4
umol/l
1.48
643
3995
211
733
3.41
48.82
17.5
7.6
11.1
9.6
mmol/l
2.15
205
698
297
1262
2.97
48.69
3.7
2.1
29.1
29.7
s
1.11
292
1221
514
2910
2.66
47.87
5.8
3.2
—
—
—
0
0
242
933
3.14
46.94
11.3
8.7
11.0
12.1
kpa
3.20
230
899
242
933
3.14
46.94
11.3
8.7
4.8
5.1
kpa
6.26
231
895
596
3650
2.69
46.91
16.7
6.4
1.2
1.2
mmol/l
1.85
568
3295
630
3967
2.74
46.84
19.6
7.1
1.2
1.2
mmol/l
1.24
525
3352
100
206
5.31
46.71
2.6
1.7
—
—
—
0
0
88
163
5.85
46.13
1.8
1.3
—
—
—
0
0
88
163
5.85
46.13
1.8
1.3
—
—
—
0
0
238
928
3.09
45.10
11.3
8.8
0.9
1.2
mmol/l
0.59
188
731
261
1081
2.95
44.32
4.2
2.5
21.7
23.5
%
1.24
232
923
42
33
13.27
43.69
33.9
34.3
108.0
126.6
ug/l
0.64
35
28
422
2252
2.57
43.23
5.7
3.1
0.3
0.5
e6/l
2.78
363
1712
74
124
6.39
42.90
8.4
3.6
1.5
1.2
%
0.31
65
108
284
1254
2.80
42.57
3.9
2.5
11.7
13.3
umol/l
3.77
268
1159
58
75
8.17
42.50
1.9
1.1
—
—
u/ml
—
0
0
268
1150
2.85
42.40
4.0
2.4
2.2
2.3
g/l
3.70
252
1066
112
277
4.45
41.90
2.1
1.6
600.0
182.0
titre
—
5
10
141
414
3.82
41.77
10.8
11.2
24.2
24.5
mmol/l
0.50
132
387
47
48
10.25
41.25
6.3
3.1
—
—
—
0
0
189
676
3.24
41.19
5.6
2.8
63.2
66.6
g/l
5.52
181
618
204
768
3.11
40.73
9.4
3.5
1.9
2.0
mmol/l
0.03
167
606
43
43
10.43
38.27
4.1
1.9
—
—
—
0
0
43
43
10.43
38.27
4.1
1.9
—
—
—
0
0
43
43
10.43
38.27
4.1
1.9
—
—
—
0
0
43
43
10.43
38.27
4.0
1.9
—
—
—
0
0
77
155
5.32
36.77
6.9
3.8
58.8
58.4
%
0.07
77
155
385
2112
2.38
35.46
7.2
2.7
3353.8
7083.8
umol/l
1.09
356
1837
129
397
3.60
35.43
9.3
3.7
24.0
24.2
mmol/l
0.24
116
363
37
35
10.96
34.16
4.5
2.1
—
—
—
0
0
37
35
10.96
34.16
4.5
2.1
—
—
—
0
0
37
36
10.65
33.51
4.5
2.0
—
—
—
0
0
93
240
4.19
32.74
1.5
1.6
0.5
0.0
iu/ml
0.61
24
46
186
761
2.79
31.31
3.2
2.1
353.3
374.5
nmol/l
0.45
177
709
25
14
18.31
30.86
1.4
1.0
—
—
—
0
0
42
55
7.94
30.37
1.4
1.3
—
—
—
0
0
72
161
4.76
30.37
2.4
2.7
15.1
15.9
%
0.69
35
87
91
245
4.00
30.20
1.9
1.2
—
—
—
0
0
29
23
12.97
29.86
1.1
1.0
—
—
—
0
0
787
6141
2.62
28.61
23.3
7.8
82.1
78.8
u/l
1.07
770
5775
131
467
3.09
28.16
1.7
1.5
—
—
—
0
0
317
1737
2.24
27.94
2.4
1.7
1.9
1.2
mg/l
1.01
268
1344
37
46
8.33
27.90
12.8
7.3
51.6
74.1
u/ml
0.29
15
15
650
4719
2.19
27.28
11.5
5.0
6.7
6.7
mmol/l
0.04
632
4418
56
112
5.25
26.86
5.8
6.2
11.8
10.9
mg/l
0.58
51
102
430
2687
2.09
26.76
8.9
3.6
2.3
2.4
mmol/l
2.09
405
2353
172
735
2.64
26.28
12.0
7.5
1.4
1.4
mmol/l
0.07
166
706
200
923
2.48
26.00
5.9
2.8
7.2
8.7
umol/l
0.56
179
814
687
5191
2.16
24.67
6.8
4.4
63.0
2721.2
e6/l
—
7
77
83
244
3.63
24.21
2.0
1.4
0.2
0.2
g/l
0.07
77
232
85
256
3.55
23.91
2.0
1.4
1.1
1.2
g/l
0.24
80
243
85
257
3.53
23.77
8.2
3.8
52.8
76.2
mg/l
0.43
66
207
408
2589
2.01
23.50
6.7
3.4
34.2
33.3
u/l
0.12
392
2475
84
254
3.53
23.48
8.1
3.8
1.3
1.8
ratio
—
5
24
38
60
6.55
23.23
1.1
1.2
—
—
—
0
0
84
257
3.49
23.06
8.3
3.8
56.0
44.1
mg/l
0.37
66
209
99
336
3.17
23.01
2.3
2.2
42.4
39.8
u/l
0.45
88
300
166
748
2.48
22.49
3.5
2.4
36.5
33.4
u/l
0.40
145
644
21
16
13.40
22.02
2.1
1.4
—
—
—
0
0
29
36
8.28
21.85
4.5
4.2
—
—
—
0
0
269
1504
2.10
21.63
5.0
3.9
256.8
329.3
ng/l
0.31
229
1187
148
645
2.53
21.47
3.7
3.0
202.5
199.9
ng/l
0.03
135
582
87
286
3.25
21.29
6.1
2.6
9.5
10.6
g/l
0.74
73
248
145
633
2.52
20.94
10.6
3.7
1.2
1.2
mmol/l
2.09
136
542
328
1991
1.99
20.89
2.8
2.2
3.2
3.1
mg/l
0.37
296
1686
90
308
3.12
20.59
6.0
2.6
3.7
3.7
g/l
0.16
67
229
90
308
3.12
20.59
6.0
2.6
—
—
—
0
0
90
308
3.12
20.59
6.0
2.6
7.7
7.3
g/l
1.07
69
238
249
1381
2.09
20.29
4.4
2.7
0.9
1.1
e6/l
0.24
158
789
110
429
2.77
19.88
18.0
12.5
—
—
—
0
0
163
773
2.34
19.54
2.5
2.4
0.2
0.2
g/l
0.68
146
728
42
87
5.00
19.35
3.9
2.4
—
—
—
0
0
234
1290
2.08
19.25
4.8
2.9
1.6
2.0
e6/l
0.59
146
700
30
45
6.85
19.22
3.4
1.8
—
—
—
0
0
30
45
6.85
19.22
3.4
1.8
—
—
—
0
0
84
290
3.08
18.91
6.4
2.6
3.4
3.1
g/l
1.38
67
232
69
212
3.43
18.79
2.2
2.3
12.7
11.7
mg/l
0.38
63
195
37
72
5.31
18.28
10.5
3.5
60.0
55.6
%
0.47
26
55
723
5845
1.98
17.90
8.7
4.1
18.8
12.1
mm/h
15.93
699
5394
25
33
7.75
17.89
2.0
2.4
55.1
67.2
ug/l
0.30
25
33
16
11
14.78
17.65
4.8
7.1
—
—
—
0
0
527
3869
1.81
17.61
7.2
4.9
0.0
0.0
estimate
0.00
135
735
527
3870
1.81
17.59
5.4
3.6
0.0
0.0
estimate
0.00
133
732
531
3912
1.81
17.49
5.4
3.6
0.0
0.0
estimate
0.50
129
701
253
1480
1.97
17.42
5.1
3.2
2.5
2.4
mmol/l
0.39
231
1303
165
827
2.20
17.20
6.0
3.3
—
—
—
0
0
63
194
3.41
17.09
1.2
1.3
—
—
—
0
0
134
618
2.36
17.01
6.3
3.9
111.9
84.1
ng/l
2.33
124
549
121
536
2.44
16.79
5.4
3.6
4.9
5.1
kpa
2.52
112
501
65
207
3.30
16.72
4.3
2.9
24.5
25.0
mmol/l
0.45
55
184
111
479
2.49
16.29
2.3
1.7
—
—
—
0
0
17
15
11.52
16.24
1.8
2.3
—
—
—
0
0
76
271
2.96
16.16
5.6
2.8
0.9
1.4
g/l
0.57
68
240
56
166
3.52
16.11
1.8
1.5
—
—
—
0
0
114
506
2.42
15.72
5.5
3.7
1.4
1.8
mmol/l
0.64
87
383
371
2520
1.77
15.57
3.4
2.6
59.4
56.8
u/l
0.38
348
2338
61
196
3.26
15.47
1.1
1.1
—
—
—
0
0
348
2324
1.78
15.45
4.5
3.1
2040.7
1305.0
ng/l
1.65
319
1970
16
14
11.61
15.34
1.9
1.0
—
—
—
0
0
305
1964
1.81
15.27
4.3
2.3
—
—
—
0
0
71
252
2.96
15.22
5.4
2.6
35.3
37.6
g/l
1.96
65
219
67
232
3.03
14.99
1.6
1.3
—
—
—
0
0
441
3172
1.73
14.94
3.1
2.3
77.5
77.2
nmol/l
0.07
416
2827
35
78
4.62
14.80
1.4
1.3
—
—
—
0
0
504
3767
1.72
14.79
8.0
4.1
—
—
—
0
0
454
3330
1.69
14.02
4.6
2.8
290.8
140.9
ug/l
2.38
428
3053
105
477
2.35
13.71
2.0
1.2
183.3
255.4
u/ml
0.48
91
433
770
6565
1.90
13.56
51.7
17.7
14.6
13.7
%
26.06
764
6433
291
1908
1.76
13.39
1.8
1.5
19.3
20.5
nmol/l
0.75
261
1604
54
176
3.19
13.39
1.7
1.3
4.6
43.3
e6/l
0.73
46
140
54
176
3.19
13.39
1.7
1.3
187.4
782.3
e6/l
0.47
49
144
53
173
3.19
13.11
2.1
2.3
119.9
128.6
g/l
1.57
39
130
89
394
2.39
12.30
7.2
2.5
0.6
0.6
%
0.17
84
380
108
524
2.20
12.04
14.0
8.2
24.7
24.5
mmol/l
0.20
102
494
37
101
3.77
12.03
1.2
1.1
—
—
—
0
0
150
829
1.96
11.79
5.0
4.6
16.9
31.0
ug/l
0.42
122
696
64
251
2.66
11.40
2.2
1.9
—
—
—
0
0
28
65
4.41
11.29
1.6
1.2
104.0
95.0
titre
—
5
12
12
11
11.04
11.08
1.3
1.2
—
—
—
0
0
39
117
3.43
11.05
1.4
1.2
1.5
4.4
u/ml
0.72
12
34
341
2431
1.63
11.03
3.1
2.1
112.6
259.2
u/l
3.07
324
2290
37
108
3.52
10.93
1.1
1.1
—
—
—
0
0
592
4822
1.60
10.84
3.6
2.9
—
—
—
0
0
34
97
3.60
10.40
1.4
1.3
—
—
—
0
0
61
245
2.59
10.37
1.4
1.1
—
—
—
0
0
36
107
3.46
10.36
3.2
2.2
32.0
33.1
pg
0.68
36
107
41
135
3.13
10.03
1.3
1.1
—
—
—
0
0
867
7886
2.10
10.03
48.0
14.4
25.5
24.2
mg/l
0.66
780
6240
222
1460
1.68
9.66
1.8
1.7
1175.8
1183.2
nmol/l
0.04
181
1097
59
244
2.51
9.46
1.4
1.1
—
—
—
0
0
401
3074
1.53
8.99
5.0
3.6
31.3
50.7
ng/l
0.90
321
2187
14
21
6.75
8.91
1.6
1.3
—
—
—
0
0
21
47
4.55
8.86
3.8
1.8
—
—
—
0
0
30
89
3.45
8.68
1.7
1.3
2369.1
1655.6
e6/l
0.36
24
57
36
121
3.05
8.54
1.4
1.2
5.4
7.9
u/ml
0.37
13
55
51
207
2.55
8.52
1.7
1.4
13.2
9.5
u/l
0.78
40
160
57
247
2.39
8.29
2.2
1.7
—
—
—
0
0
16
30
5.41
8.22
2.2
1.4
—
—
—
0
0
114
649
1.86
8.11
3.1
2.7
60.7
65.8
ml/min/173m2
0.57
37
267
27
80
3.44
7.84
6.1
2.2
—
—
—
0
0
36
128
2.88
7.76
1.2
1.3
—
—
—
0
0
35
125
2.87
7.49
1.1
1.1
—
13.9
—
0
7
12
19
6.38
7.25
1.0
1.1
—
—
—
0
0
11
16
6.94
7.16
5.5
1.3
—
—
—
0
0
26
80
3.31
7.14
1.1
1.2
57.1
59.0
u/l
0.05
20
55
115
683
1.78
7.12
2.2
2.4
8.4
7.1
ug/l
0.29
105
609
74
382
2.02
7.03
7.8
3.7
53.7
48.9
%
0.83
74
376
19
48
4.02
6.91
1.8
1.6
8.6
4.0
u/l
0.33
14
25
791
7178
1.60
6.83
43.2
15.5
38.2
40.0
%
7.02
554
5113
405
3235
1.44
6.82
2.3
2.0
93.9
94.6
pmol/l
0.12
245
1677
76
402
1.97
6.74
1.5
1.3
—
—
—
0
0
24
73
3.35
6.72
1.1
1.0
—
—
—
0
0
25
79
3.22
6.60
1.8
1.3
12090.2
130844.6
e6/l
0.73
16
40
280
2096
1.48
6.59
6.1
4.0
0.0
0.0
estimate
0.69
117
713
62
308
2.08
6.54
5.6
2.0
—
—
—
0
0
18
46
3.97
6.46
2.4
1.2
—
—
—
0
0
22
66
3.39
6.30
1.3
1.5
—
—
—
0
0
57
280
2.10
6.20
3.1
1.8
—
—
—
0
0
42
182
2.37
6.16
2.0
1.3
—
—
—
0
0
45
202
2.29
6.10
1.4
1.2
—
—
—
0
0
38
161
2.42
5.87
1.1
1.2
—
—
—
0
0
49
234
2.15
5.74
1.5
1.4
243.0
291.0
ug/g
0.85
26
135
17
46
3.74
5.66
2.5
1.2
—
—
—
0
0
43
196
2.25
5.64
3.0
3.3
33.7
34.7
umol/l
0.12
38
164
18
51
3.58
5.62
1.3
1.4
5.5
6.4
u/l
0.36
12
43
9
7
12.96
5.59
1.3
1.1
—
—
—
0
0
19
59
3.27
5.19
1.7
1.1
6.2
0.4
u/ml
—
9
29
17
49
3.51
5.19
1.0
1.0
—
—
—
0
0
15
41
3.70
4.94
3.7
2.4
93.1
105.0
%
0.50
15
41
13
32
4.10
4.91
7.0
3.2
240.1
202.2
u/l
0.51
13
32
179
1293
1.47
4.90
1.5
1.5
—
—
—
0
0
23
83
2.81
4.90
1.1
1.1
101.9
96.0
%
0.54
23
77
187
1363
1.46
4.89
1.3
1.3
53.4
33.0
iu/ml
0.86
62
431
22
78
2.86
4.84
1.1
1.1
—
—
—
0
0
15
42
3.61
4.78
1.2
1.1
1.1
1.0
ratio
—
7
13
14
38
3.72
4.66
1.4
1.3
—
—
—
0
0
44
220
2.05
4.63
1.6
1.4
—
—
—
0
0
28
116
2.46
4.58
1.1
1.1
—
—
—
0
0
363
2991
1.35
4.56
5.8
3.8
—
—
—
0
0
20
71
2.86
4.41
1.7
1.3
32.0
32.1
%
0.01
14
51
590
5238
1.33
4.35
4.6
3.2
72.1
52.3
u/l
3.11
555
4875
73
440
1.71
4.33
2.7
3.2
4.1
4.6
pmol/l
3.14
62
378
865
8193
1.60
4.33
47.3
16.9
4.0
4.0
mmol/l
3.43
857
7971
21
79
2.70
4.18
1.0
1.1
—
—
—
0
0
26
109
2.42
4.17
2.3
1.4
—
—
—
0
0
12
32
3.79
4.09
1.3
1.4
52.7
55.4
%
0.09
12
23
884
8436
1.66
4.05
28.2
10.7
26.4
27.0
u/l
0.63
870
8134
17
59
2.92
3.91
1.3
1.2
—
—
—
0
0
17
59
2.92
3.91
1.3
1.2
—
—
—
0
0
16
54
3.00
3.86
1.2
1.2
—
—
—
0
0
860
8168
1.54
3.86
46.6
16.8
139.0
139.6
mmol/l
10.26
854
7962
56
324
1.77
3.86
4.4
3.6
573.2
4388.8
u/ml
0.66
46
279
25
107
2.37
3.85
2.4
1.4
—
—
—
0
0
17
60
2.87
3.80
1.3
1.2
—
—
—
0
0
17
60
2.87
3.80
1.3
1.2
—
—
—
0
0
17
60
2.87
3.80
1.3
1.2
—
—
—
0
0
12
34
3.56
3.77
1.1
1.3
—
—
—
0
0
21
84
2.53
3.73
1.0
1.1
—
—
—
0
0
25
109
2.33
3.71
2.4
1.4
—
—
—
0
0
15
50
3.03
3.70
1.0
1.0
—
—
—
0
0
9
16
5.67
3.66
1.3
1.4
—
—
—
0
0
38
198
1.96
3.62
1.2
1.4
217.3
233.3
miu/ml
—
9
92
31
150
2.10
3.60
3.0
2.9
0.9
0.9
nmol/l
0.17
26
115
14
46
3.07
3.54
1.2
1.1
—
—
—
0
0
38
203
1.91
3.39
1.4
1.2
5.7
6.1
u/ml
—
6
29
170
1298
1.38
3.38
1.2
1.3
27.7
12.2
u/ml
0.81
43
495
7
10
7.04
3.36
1.1
1.3
—
—
—
0
0
6
7
8.62
3.26
1.2
1.3
—
—
—
0
0
18
72
2.53
3.22
1.0
1.0
—
—
—
0
0
7
11
6.40
3.19
9.0
9.4
5.0
6.5
mmol/l
—
7
11
48
284
1.73
3.11
1.6
1.4
38.8
28.0
iu/l
0.91
38
238
12
39
3.10
3.09
2.7
1.2
—
—
—
0
0
12
39
3.10
3.09
2.7
1.2
—
—
—
0
0
34
183
1.89
2.99
3.8
2.2
5680.2
3017.6
u/l
0.21
12
73
23
107
2.18
2.98
2.4
1.4
—
—
—
0
0
23
107
2.18
2.98
2.4
1.4
—
—
—
0
0
23
108
2.16
2.92
2.4
1.4
—
—
—
0
0
9
22
4.12
2.88
1.4
1.2
—
—
—
0
0
5
6
8.37
2.75
1.0
1.0
—
—
—
0
0
30
160
1.90
2.73
1.4
1.2
40.3
30.4
u/ml
—
7
12
132
1002
1.37
2.72
30.6
23.1
1.6
1.3
inr
0.68
13
135
20
92
2.20
2.68
1.9
1.5
59.8
58.4
%
0.05
12
63
14
55
2.57
2.62
1.1
1.6
—
—
—
0
0
34
192
1.80
2.61
1.9
1.6
6723.8
13434.2
e6/l
1.03
26
146
7
15
4.69
2.60
1.0
1.1
—
—
—
0
0
7
15
4.69
2.60
1.0
1.1
105.3
94.4
%
—
7
15
71
1007
0.68
2.52
3.7
4.6
29.1
31.9
%
1.75
54
670
786
7465
1.30
2.48
37.3
13.4
77.6
81.0
ml/min/173m2
3.41
713
6162
7
16
4.40
2.47
2.4
1.2
—
—
—
0
0
12
46
2.63
2.36
1.1
1.3
—
53.3
—
0
6
204
1697
1.26
2.17
1.2
1.2
0.9
1.5
u/ml
1.08
36
465
38
236
1.64
2.13
1.4
1.4
241.3
289.7
mu/l
0.74
33
218
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
49
2.47
2.11
1.2
1.2
—
—
—
0
0
87
646
1.38
2.09
2.4
2.2
11.1
13.1
nmol/l
1.29
75
574
5
10
5.02
2.07
2.8
1.7
—
—
—
0
0
5
10
5.02
2.07
1.0
1.0
—
—
—
0
0
12
50
2.42
2.03
1.1
1.4
—
275.0
—
0
6
635
5945
1.20
1.97
4.3
3.8
14.8
14.8
pmol/l
0.16
580
5370
9
34
2.66
1.87
1.3
1.1
—
—
—
0
0
8
28
2.87
1.86
1.0
1.1
—
—
—
0
0
8
28
2.87
1.86
1.0
1.1
—
—
—
0
0
6
17
3.54
1.84
1.0
1.2
—
—
—
0
0
899
8781
1.42
1.74
60.3
21.3
4.2
4.5
e12/l
33.73
890
8540
9
36
2.51
1.74
4.9
2.4
25.8
259.7
ug/l
—
9
29
12
56
2.16
1.61
2.7
1.6
1.0
1.0
g/l
0.11
12
56
16
84
1.92
1.60
1.4
1.2
—
—
—
0
0
288
2557
1.18
1.56
4.9
3.2
6.9
7.7
mmol/l
2.16
254
2142
5
15
3.35
1.52
1.6
2.5
—
—
—
0
0
48
660
0.71
1.50
1.4
1.8
—
—
—
0
0
9
37
2.45
1.48
1.0
1.0
—
—
—
0
0
10
46
2.19
1.40
1.2
1.1
—
—
—
0
0
10
46
2.19
1.40
1.1
1.4
—
—
—
0
0
5
17
2.95
1.36
1.8
1.2
0.3
0.3
ug/l
—
5
11
5
115
0.43
1.25
1.6
1.6
—
—
—
0
0
777
8002
0.84
1.24
5.1
5.0
2.7
2.7
mmol/l
1.15
714
7340
8
37
2.17
1.21
1.3
1.2
—
21.3
u/ml
—
0
6
243
2178
1.16
1.15
1.7
1.7
1.5
1.4
mmol/l
1.34
208
1812
40
293
1.38
1.13
1.8
1.9
—
—
—
0
0
11
59
1.87
1.07
2.0
1.2
2.1
3.2
ug/l
0.60
11
53
7
33
2.13
1.05
8.4
1.9
—
—
—
0
0
48
367
1.32
1.05
1.9
2.0
—
—
—
0
0
16
99
1.63
1.00
2.3
2.6
32.6
22.3
mg/l
—
5
29
740
7173
1.14
0.95
5.3
4.6
2.0
2.1
mu/l
0.22
678
6524
21
141
1.50
0.95
1.6
1.7
—
—
—
0
0
6
29
2.08
0.89
1.0
1.1
—
—
—
0
0
6
29
2.08
0.89
1.0
1.2
—
—
—
0
0
6
29
2.08
0.89
1.0
1.2
—
—
—
0
0
11
64
1.73
0.86
1.0
1.2
—
79.0
—
0
6
79
671
1.19
0.76
1.7
1.9
—
—
—
0
0
273
2532
1.11
0.75
5.7
4.1
17.7
9.1
mg/mmol
1.72
192
1601
63
527
1.21
0.72
1.3
1.2
115.0
150.2
iu/ml
0.34
19
209
5
26
1.93
0.70
1.2
1.2
40.5
30.3
nmol/l
—
5
21
765
7815
0.89
0.70
4.7
4.4
1.4
1.4
mmol/l
1.35
702
7169
18
250
0.71
0.68
1.6
1.6
—
—
—
0
0
770
7861
0.89
0.68
4.8
4.5
4.6
4.6
mmol/l
0.77
714
7262
111
980
1.15
0.68
1.8
1.8
1.7
1.5
%
0.93
90
857
7
42
1.67
0.68
1.3
1.1
—
—
—
0
0
5
28
1.79
0.66
1.6
1.1
—
—
—
0
0
5
28
1.79
0.66
1.0
1.2
10.2
8.8
ug/l
—
5
28
5
30
1.67
0.61
1.6
1.1
—
—
—
0
0
11
162
0.68
0.59
1.5
1.5
—
—
—
0
0
182
1676
1.11
0.58
1.7
1.7
463.5
20788175.3
pmol/l
1.20
154
1371
9
62
1.46
0.53
1.9
1.2
—
—
—
0
0
9
62
1.46
0.53
1.9
1.2
—
—
—
0
0
219
2340
0.92
0.52
3.6
4.3
21.8
21.1
%
0.22
105
1120
46
389
1.19
0.51
1.0
1.0
—
—
—
0
0
7
107
0.65
0.49
1.0
1.0
—
—
—
0
0
185
1728
1.09
0.45
5.5
4.0
1.0
1.0
kg/l
0.11
29
235
16
205
0.78
0.40
1.5
1.4
—
—
—
0
0
27
223
1.22
0.40
2.2
2.5
175.3
103.8
ug/min
0.47
20
132
28
235
1.20
0.36
1.6
1.8
45.1
39.7
nmol/l
0.47
28
226
82
748
1.11
0.35
2.0
2.0
—
—
—
0
0
6
89
0.67
0.33
1.7
1.6
—
—
—
0
0
301
2906
1.05
0.29
4.3
5.0
2.9
2.5
ug/l
0.28
267
2586
726
7347
0.95
0.26
6.5
5.9
39.6
40.0
mmol/mol
0.49
683
6784
163
1698
0.95
0.21
2.2
3.1
0.6
0.8
ug/l
1.15
116
1118
0
11
0.00
0.21
0.0
1.6
—
0.5
—
0
11
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
3.0
—
72.2
—
0
11
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
12
145
0.83
0.21
1.5
1.6
—
—
—
0
0
11
131
0.84
0.17
1.5
1.5
—
—
—
0
0
11
131
0.84
0.17
1.5
1.5
—
—
—
0
0
11
130
0.84
0.16
1.5
1.5
—
—
—
0
0
11
130
0.84
0.16
1.5
1.5
—
—
—
0
0
15
171
0.88
0.14
4.2
3.6
30.7
22.0
mg/l
—
10
107
7
90
0.78
0.14
1.7
1.4
—
—
—
0
0
24
261
0.92
0.11
1.5
1.8
—
—
—
0
0
757
7526
1.03
0.11
4.4
4.0
1.4
1.3
mmol/l
1.26
691
6875
767
7712
0.97
0.11
5.1
4.6
6.0
6.0
mmol/l
0.04
710
6997
7
84
0.83
0.07
1.3
1.2
—
—
—
0
0
9
84
1.07
0.07
1.4
1.3
32.3
29.2
u/l
—
9
72
9
102
0.88
0.06
1.7
1.8
—
—
—
0
0
97
989
0.98
0.05
19.1
7.2
—
—
—
0
0
13
123
1.06
0.01
1.0
1.1
0.6
2.9
u/ml
—
7
53
23
223
1.03
0.01
1.3
1.3
—
—
—
0
0
12
123
0.98
0.00
1.4
1.6
—
—
—
0
0
8
81
0.99
0.00
1.1
1.2
1.3
1.4
nmol/l
—
8
73
106
1060
1.00
0.00
1.5
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_PROTOZOAL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_PROTOZOAL | 3.997 [3.21, 4.98] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.171 |
During the follow-up period (1.1.1998 — 31.12.2019), 470 out of 1914 females with AB1_PROTOZOAL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_PROTOZOAL | 3.555 [2.88, 4.38] | < 0.001 |
| Birth year | 0.981 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 575 out of 2159 males with AB1_PROTOZOAL died.
Mortality risk
Mortality risk for people of age
years, who have AB1_PROTOZOAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.377% | 0.561% |
| 5 | 2.125% | 3.161% |
| 10 | 5.209% | 8.234% |
| 15 | 9.94% | 14.814% |
| 20 | 17.521% | 24.247% |
Relationships between endpoints
↥Index endpoint: AB1_PROTOZOAL – Protozoal diseases
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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