Other disorders of central nervous system

G6_CNSOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G96
  • Hospital discharge: ICD-9 3498A|3492|3499
  • Cause of death: ICD-10 G96
  • Cause of death: ICD-9 3498A|3492|3499

2 out of 7 registries used, show all original rules.

467

4. Check minimum number of events

None

467

5. Include endpoints

None

467

6. Filter based on genotype QC (FinnGen only)

454

Control definitions (FinnGen only)

Control exclude
G6_OTHNEU

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G90-G99
Name in latin
Aliae morbositates systematis nervosi centralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3599 1799 1755
Only index persons 2683 1459 1224
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.05
Only index persons 0.05 0.05 0.05
Median age at first event (years)
Whole population 51.05 50.08 51.69
Only index persons 46.73 46.94 46.48

-FinnGen-

Key figures

All Female Male
Number of individuals 454 281 173
Unadjusted period prevalence (%) 0.09 0.10 0.08
Median age at first event (years) 48.94 46.23 53.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
467
Matched controls
4670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
+∞
248.9
216
*
G96.9
ICD-10 Finland
Disorder of central nervous system, unspecified
+∞
127.0
116
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
9.7
94.5
130
179
3499X
ICD-9 Finland
Other and unspecified disorders of the nervous system, Unspecified disorders of nervous system
+∞
81.7
76
*
AA1AD
NOMESCO Finland
CT of head and brain
5.4
70.0
207
599
TAB00
NOMESCO Finland
Lumbar puncture
8.5
52.8
74
101
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
6.2
51.2
101
199
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
11.3
46.6
51
50
G96.8
ICD-10 Finland
Other specified disorders of central nervous system
+∞
44.5
42
*
M03BX01
ATC
baclofen; systemic
14.1
41.3
39
30
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
60.5
38.1
44
8
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
7.1
36.3
58
91
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
13.0
35.4
35
29
N03AX14
ATC
levetiracetam; systemic
10.5
33.4
38
39
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
182.9
33.2
34
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.2
32.3
74
164
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
10.8
32.2
36
36
R51.80
ICD-10 Finland
Headache
3.6
31.4
135
478
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
7.0
26.0
41
63
G96.1
ICD-10 Finland
Disorders of meninges, not elsewhere classified
+∞
25.2
24
*
XA800
NOMESCO Finland
Neuropsychological investigation
5.9
24.8
47
87
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
252.4
23.9
24
*
XCK00
NOMESCO Finland
Perimetry
5.0
23.8
55
122
H02AB09
ATC
hydrocortisone; systemic
7.4
22.8
34
49
N03AF02
ATC
oxcarbazepine; oral
6.5
22.4
38
63
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.3
22.3
47
96
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.8
22.1
75
223
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.4
20.6
85
287
N03AX12
ATC
[U] gabapentin; oral
3.0
20.4
110
436
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
24.7
20.2
28
12
N03AX16
ATC
[U] pregabalin
2.7
19.8
140
640
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
18.9
18
*
WX882
NOMESCO Finland
High dependency care
6.3
18.5
32
54
R1250
NOMESCO Finland
Evaluation of functional capability
6.5
17.9
30
49
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
69.4
17.9
20
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.9
17.4
97
389
ZXD05
NOMESCO Finland
Urgent procedure
2.4
17.3
179
967
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.8
17.2
32
58
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.6
16.7
24
33
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
13.5
16.4
28
22
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
16.2
89
353
ZXC95
NOMESCO Finland
Use of surgical navigator
14.3
16.2
27
20
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.6
16.2
57
173
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
16.0
74
266
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
6.9
15.9
25
38
S18
ICPC
Laceration/cut
2.2
15.9
234
1454
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
+∞
15.7
15
*
G35
ICD-10 Finland
Multiple sclerosis
15.5
15.5
25
17
WX402
NOMESCO Finland
General anaesthesia
2.5
15.5
119
559
X59
ICD-10 Finland
Exposure to unspecified factor
2.5
15.3
118
554
AA1BD
NOMESCO Finland
Extensive CT of head and brain
6.8
15.1
24
37
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
+∞
14.7
14
*
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
23.1
14.3
20
9
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
14.0
216
1347
109
Kela drug reimbursment
Multiple sclerosis
20.8
13.9
20
10
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
13.9
121
599
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
13.6
144
774
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
13.5
85
360
N03AE01
ATC
clonazepam; systemic
3.8
13.5
42
117
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
13.2
116
575
XKC03
NOMESCO Finland
Water cystometry
5.4
13.1
26
50
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
13.5
13.0
22
17
G82.2
ICD-10 Finland
Paraplegia, unspecified
29.3
13.0
17
6
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.0
13.0
38
101
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
23.3
13.0
18
8
XKD06
NOMESCO Finland
Physiologic investigation of micturition
5.6
12.9
25
47
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.7
12.7
41
117
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
12.6
12
*
AAK10
NOMESCO Finland
Repair of dura
133.4
12.5
13
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.0
12.4
61
226
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
14.9
12.4
20
14
L28
ICPC
Limited function/disability (L)
2.5
12.3
87
389
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.7
12.3
29
65
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.0
12.3
27
57
Z3226
NOMESCO Finland
Physiotherapist
2.3
12.2
106
520
R20.2
ICD-10 Finland
Paraesthesia of skin
3.3
12.2
49
161
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
16.4
12.2
19
12
UDM02
NOMESCO Finland
Sinoscopy
5.7
12.2
23
42
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.0
12.1
56
201
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.9
11.9
62
237
N18
ICPC
Paralysis/weakness
10.0
11.9
23
24
R42
ICD-10 Finland
Dizziness and giddiness
2.3
11.8
108
542
M54.4
ICD-10 Finland
Lumbago with sciatica
2.3
11.7
99
481
H02AB06
ATC
prednisolone; systemic
2.0
11.6
231
1549
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
+∞
11.5
11
*
ZZC00
NOMESCO Finland
Graft of fascia
122.9
11.5
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
11.4
71
298
L89
ICD-10 Finland
Decubitus ulcer and pressure area
9.2
11.4
23
26
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.6
11.4
39
116
R55
ICD-10 Finland
Syncope and collapse
2.8
11.2
60
233
R4120
NOMESCO Finland
Occupational therapy
3.2
11.1
45
149
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
10.9
179
1119
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
10.8
48
168
G03.9
ICD-10 Finland
Meningitis, unspecified
28.8
10.8
14
5
Z2446
NOMESCO Finland
Social worker
3.1
10.7
47
163
R50.9
ICD-10 Finland
Fever, unspecified
2.3
10.7
88
420
R4110
NOMESCO Finland
Physiotherapy
2.0
10.7
142
821
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
10.6
113
601
N02AX02
ATC
tramadol; systemic, rectal
1.9
10.5
206
1362
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
112.4
10.5
11
*
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
33.3
10.4
13
*
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
4.9
10.3
23
49
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
10.3
59
237
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
19.3
10.3
15
8
TKC20
NOMESCO Finland
Catheterisation of bladder
3.3
10.2
40
130
R53
ICD-10 Finland
Malaise and fatigue
2.1
10.1
123
687
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
9.0
9.9
20
23
A28
ICPC
Limited function/disability NOS
2.4
9.8
77
360
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.5
9.7
24
56
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
9.5
52
204
ZX120
NOMESCO Finland
Intravenous
2.7
9.4
55
223
R41.0
ICD-10 Finland
Disorientation, unspecified
5.3
9.4
19
37
DC1AD
NOMESCO Finland
Temporalbone CT
12.7
9.4
16
13
G93.2
ICD-10 Finland
Benign intracranial hypertension
+∞
9.4
9
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
+∞
9.4
9
*
L04AA31
ATC
[U] teriflunomide
+∞
9.4
9
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
+∞
9.4
9
*
S02.10
ICD-10 Finland
Fracture of base of skull, closed
22.2
9.4
13
6
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
9.4
96
501
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
11.0
9.4
17
16
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
11.8
9.1
16
14
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
16.0
9.1
14
9
J01DB01
ATC
cefalexin; oral
2.2
9.1
386
3218
E23.00
ICD-10 Finland
Panhypopituitarism
37.5
9.1
11
*
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
9.0
98
523
A02BC02
ATC
pantoprazole; systemic
1.9
9.0
306
2363
Z2445
NOMESCO Finland
Psychologist
3.4
8.9
33
103
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
8.9
32
98
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
8.9
32
98
Z3231
NOMESCO Finland
Registered nurse
1.9
8.9
138
836
N06AA09
ATC
amitriptyline; systemic
2.6
8.7
52
213
UJF32
NOMESCO Finland
Coloscopy
2.0
8.7
116
666
N02BE01
ATC
paracetamol; systemic, rectal
2.4
8.7
411
3531
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.7
8.7
20
44
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
8.7
76
372
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
11.9
8.6
15
13
ZXA10
NOMESCO Finland
Bilateral
2.1
8.6
92
488
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.7
8.5
48
192
N99
ICPC
Neurological disease other
13.1
8.4
14
11
N03AG01
ATC
valproic acid; systemic, rectal
3.0
8.4
37
129
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
8.4
8
*
N28
ICPC
Limited function/disability (N)
11.0
8.3
15
14
R13
ICD-10 Finland
Dysphagia
2.9
8.3
39
141
CS494
NOMESCO Finland
Other visual field testing
6.7
8.3
20
31
H53.2
ICD-10 Finland
Diplopia
4.0
8.2
23
59
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.0
8.2
23
59
101
Kela drug reimbursment
Anterior pituitary hypofunction
14.8
8.2
13
9
WX002
NOMESCO Finland
Sedation and analgesia
2.1
8.2
91
489
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
7.0
8.1
19
28
PA2AD
NOMESCO Finland
CT angiography of brain
34.0
8.1
10
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.4
8.1
29
89
L03AB07
ATC
interferon beta-1a; parenteral
22.5
8.0
11
5
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
13.3
7.9
13
10
J01EA01
ATC
trimethoprim; systemic
1.9
7.9
124
750
R01AD08
ATC
fluticasone; nasal
1.8
7.8
142
899
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
7.8
71
352
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.2
7.8
72
360
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.6
7.7
18
40
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
4.1
7.7
21
53
R11
ICD-10 Finland
Nausea and vomiting
2.5
7.7
50
214
H53.1
ICD-10 Finland
Subjective visual disturbances
2.9
7.7
36
130
L03AX13
ATC
glatiramer acetate; parenteral
18.7
7.6
11
6
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
6.3
7.6
19
31
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
10.3
7.6
14
14
N06AB04
ATC
citalopram; systemic
1.9
7.5
103
594
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
7.5
205
1457
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.5
7.5
18
41
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.7
7.4
23
64
ZZF00
NOMESCO Finland
Graft of adipose tissue
8.6
7.4
15
18
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.9
7.3
34
122
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
+∞
7.3
7
*
AWW99
NOMESCO Finland
Other reoperation in surgery of the nervous system
+∞
7.3
7
*
AWC00
NOMESCO Finland
Reoperation of nervous system because of deep wound infection in the nervous system
+∞
7.3
7
*
J01DA01
ATC
[U] cefalexin
1.7
7.3
285
2228
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.2
7.3
28
90
M54.5
ICD-10 Finland
Low back pain
1.7
7.3
166
1121
ZXA05
NOMESCO Finland
Left side
1.9
7.2
111
664
WX892
NOMESCO Finland
Monitored bed care
2.7
7.2
40
158
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
7.2
126
786
R35
ICD-10 Finland
Polyuria
2.9
7.2
35
129
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.6
7.2
43
177
ZXC86
NOMESCO Finland
Use of endoscopic device
20.4
7.2
10
5
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
7.1
51
228
B01AB05
ATC
enoxaparin; parenteral
1.8
7.1
142
921
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
12.3
7.1
12
10
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.7
7.1
22
61
N02BF02
ATC
pregabalin; oral
2.8
7.1
36
136
R4130
NOMESCO Finland
Speech therapy
4.0
7.1
20
52
WX110
NOMESCO Finland
Infiltration anesthesia
1.8
7.0
330
2699
L03
ICPC
Low back symptom/complaint
1.8
7.0
129
816
P01AB01
ATC
metronidazole; oral, rectal
1.7
7.0
186
1306
G44.2
ICD-10 Finland
Tension-type headache
2.1
7.0
74
389
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.6
6.9
23
67
N04BB01
ATC
amantadine; oral
8.5
6.9
14
17
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
6.8
114
700
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.9
6.8
32
116
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
40.7
6.8
8
*
H47.2
ICD-10 Finland
Optic atrophy
17.0
6.8
10
6
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
6.7
139
908
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.1
6.7
73
387
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
6.7
59
288
SPAT1167
SPAT
Insertion of urinary catheter
5.6
6.7
18
33
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.2
6.7
62
310
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.1
6.7
28
95
WX704
NOMESCO Finland
Intubation
2.5
6.7
41
171
SPAT1229
SPAT
Assessment of need for aid
2.7
6.6
35
135
N30.9
ICD-10 Finland
Cystitis, unspecified
2.7
6.6
35
135
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.9
6.6
31
112
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
6.6
73
390
H57.1
ICD-10 Finland
Ocular pain
3.2
6.6
26
85
N06AX21
ATC
duloxetine; oral
2.2
6.6
60
298
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
6.5
73
391
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.8
6.5
20
55
N02AA05
ATC
oxycodone; systemic
2.0
6.5
78
428
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
6.3
6.5
16
26
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.6
6.5
21
60
G00.1
ICD-10 Finland
Pneumococcal meningitis
70.8
6.4
7
*
C03CA01
ATC
furosemide; systemic
1.8
6.4
114
712
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
6.7
6.4
15
23
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
6.4
42
181
ZXE00
NOMESCO Finland
One hour or less
1.7
6.4
180
1278
H53.4
ICD-10 Finland
Visual field defects
5.6
6.4
17
31
WX725
NOMESCO Finland
Noninvasive ventilation
3.0
6.3
28
98
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
9.4
6.3
12
13
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
18.3
6.3
9
5
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.5
6.3
41
176
ABD40
NOMESCO Finland
Implantation of spinal injection device
+∞
6.3
6
*
D32.1
ICD-10 Finland
Benign neoplasm: Spinal meninges
+∞
6.3
6
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
+∞
6.3
6
*
Q01.1
ICD-10 Finland
Nasofrontal encephalocele
+∞
6.3
6
*
G95.0
ICD-10 Finland
Syringomyelia and syringobulbia
+∞
6.3
6
*
AAK00
NOMESCO Finland
Cranioplasty
+∞
6.3
6
*
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
+∞
6.3
6
*
N03AX11
ATC
topiramate; oral
3.8
6.3
19
52
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
6.2
167
1168
T90.5
ICD-10 Finland
Sequelae of intracranial injury
8.8
6.1
12
14
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
4.0
6.0
17
44
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
6.0
71
388

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
83
74
13.42
81.74
1.6
1.4
3.59
3.72
mmol/l
0.30
78
66
78
65
14.21
80.01
1.4
1.4
—
—
—
0
0
53
24
24.78
73.08
1.6
1.3
—
—
—
0
0
76
73
12.24
71.06
1.6
1.3
345.47
6.43
e6/l
1.39
68
58
76
73
12.24
71.06
1.7
1.4
5324.18
243.00
e6/l
0.88
67
60
47
24
21.66
61.50
1.5
1.8
—
—
—
0
0
128
470
3.37
27.74
1.9
2.3
28.75
29.57
s
1.18
123
454
30
35
9.09
23.90
1.8
1.6
—
—
—
0
0
99
341
3.42
23.46
7.0
8.6
5.18
5.17
kpa
0.02
94
323
99
341
3.42
23.46
7.0
8.6
14.30
12.26
kpa
2.55
94
325
258
1490
2.63
23.25
9.5
12.3
1.14
1.20
inr
0.49
69
438
280
1688
2.65
23.00
8.4
6.5
1.21
1.22
mmol/l
1.41
252
1442
260
1526
2.59
22.38
8.8
6.0
1.21
1.22
mmol/l
2.15
246
1398
97
343
3.31
21.94
7.1
8.7
0.58
1.36
mmol/l
0.83
79
274
313
2040
2.62
21.11
6.7
4.6
6.46
6.59
mmol/l
0.56
299
1890
104
422
2.88
18.31
2.4
1.6
—
—
—
0
0
144
699
2.53
17.72
3.6
2.8
521.11
558.77
mosm/kgh2o
1.44
131
596
199
1119
2.36
17.65
3.2
2.3
—
—
—
0
0
83
303
3.12
17.59
7.4
9.3
96.33
95.27
%
0.81
77
291
161
828
2.44
17.44
2.6
2.2
—
—
—
0
0
167
874
2.42
17.39
6.0
4.0
—
—
—
0
0
79
283
3.16
17.27
7.1
9.6
121.41
122.99
g/l
0.28
74
275
96
387
2.86
17.02
6.4
6.6
105.46
104.28
mmol/l
1.42
96
387
177
990
2.27
15.46
2.6
2.1
142.95
283.49
u/l
1.15
171
933
99
427
2.67
15.31
5.7
5.8
1.00
1.07
mmol/l
1.73
92
394
175
984
2.24
15.00
4.7
2.9
0.15
0.32
e6/l
2.05
143
728
75
283
2.97
14.89
3.6
2.6
9.65
10.58
g/l
1.02
67
260
140
725
2.33
14.53
3.2
2.6
4.75
6.60
e6/l
0.83
129
656
253
1667
2.13
14.28
3.4
2.5
—
—
—
0
0
111
522
2.48
14.27
2.8
4.0
0.83
0.82
mmol/l
0.36
106
500
106
495
2.48
13.80
2.4
2.2
—
—
—
0
0
170
972
2.18
13.75
4.6
2.9
—
—
—
0
0
178
1037
2.16
13.72
4.5
2.7
—
—
—
0
0
277
1917
2.09
13.39
9.7
6.1
0.20
0.19
e9/l
0.74
256
1697
182
1082
2.12
13.21
4.7
3.1
374.13
107.30
e6/l
0.34
149
824
49
154
3.44
13.14
6.8
9.8
23.72
24.54
mmol/l
0.91
49
149
268
1843
2.07
13.05
9.1
5.7
0.58
0.56
e9/l
0.85
246
1605
268
1845
2.06
12.99
9.1
5.7
0.04
0.04
e9/l
2.50
246
1608
47
148
3.42
12.56
6.0
13.6
—
—
—
0
0
266
1849
2.02
12.29
6.2
6.1
10.23
11.18
umol/l
0.55
254
1760
271
1897
2.02
12.26
9.4
5.8
1.86
1.98
e9/l
0.78
254
1706
224
1469
2.01
12.17
4.7
4.5
35.40
36.19
g/l
1.13
213
1379
256
1761
2.00
12.12
9.7
6.2
—
—
—
0
0
202
1281
2.02
12.04
5.5
3.7
59.04
91.18
e6/l
0.49
157
891
71
292
2.69
11.91
5.8
6.6
1.14
1.30
mmol/l
1.20
71
286
67
268
2.75
11.86
7.3
8.6
—
—
—
0
0
23
26
9.24
11.38
1.8
1.5
—
—
—
0
0
295
2162
1.99
11.32
11.9
9.1
4.31
4.05
e9/l
1.04
268
1885
15
6
25.75
11.20
1.3
1.0
31.89
—
%
—
9
0
58
223
2.83
11.04
9.1
8.3
24.77
24.86
mmol/l
0.05
58
223
52
190
2.95
10.85
10.2
9.1
25.34
24.73
mmol/l
0.59
47
179
241
1682
1.89
10.35
9.3
5.9
0.70
0.66
%
0.73
232
1570
248
1747
1.89
10.34
9.4
6.1
8.53
8.40
%
0.32
239
1636
23
50
4.79
10.11
2.3
1.6
—
—
—
0
0
245
1734
1.87
9.93
9.1
5.8
2.93
2.83
%
0.29
236
1624
323
2502
1.94
9.83
6.0
3.9
—
—
—
0
0
50
191
2.81
9.62
6.7
6.6
—
—
—
0
0
251
1806
1.84
9.50
9.5
5.9
27.59
28.56
%
0.75
243
1702
248
1784
1.83
9.33
9.0
5.7
57.65
56.87
%
0.45
240
1678
160
1021
1.86
8.74
4.8
3.7
7.40
7.40
ph
0.32
31
185
188
1266
1.81
8.60
3.8
3.4
26.26
37.14
ng/l
0.69
127
802
66
308
2.33
8.40
5.3
4.3
1.63
1.76
mmol/l
0.09
56
252
56
249
2.42
7.93
2.9
2.4
68.28
67.54
g/l
0.46
50
229
149
957
1.82
7.83
8.9
6.5
—
—
—
0
0
99
569
1.94
7.30
1.7
1.6
1167.22
1202.04
nmol/l
0.13
82
433
18
42
4.42
7.28
2.1
1.1
—
—
—
0
0
338
2775
1.79
7.21
9.2
7.1
79.33
78.48
u/l
0.13
325
2602
27
88
3.20
6.85
6.2
11.4
1.04
1.31
mmol/l
1.08
22
72
424
3776
2.33
6.79
23.1
12.4
19.39
22.51
mg/l
1.80
382
2881
332
2735
1.74
6.73
5.1
4.0
12.08
11.10
mm/h
0.63
312
2524
225
1681
1.65
6.58
13.2
8.9
0.00
0.00
e9/l
0.27
195
1371
16
27
6.10
6.35
2.9
2.4
44.41
37.13
%
1.38
16
27
96
579
1.83
6.03
4.6
2.6
2.78
2.90
e6/l
0.05
49
310
128
843
1.71
5.94
2.0
1.8
0.80
1.20
mg/l
1.77
99
648
17
46
3.80
5.69
1.4
1.4
—
—
—
0
0
19
56
3.49
5.64
1.5
1.6
0.47
0.66
g/l
0.49
13
43
77
442
1.89
5.63
3.3
2.3
21.18
23.05
%
0.52
70
385
17
47
3.72
5.53
1.4
1.4
0.55
0.56
nmol/l
0.03
17
42
31
125
2.59
5.41
6.6
4.2
—
—
—
0
0
16
34
4.83
5.35
1.4
1.4
5.37
6.80
g/l
0.62
11
23
16
34
4.83
5.35
1.4
1.4
0.28
0.37
g/l
—
10
23
16
34
4.83
5.35
1.4
1.4
2.21
2.64
g/l
0.34
11
23
16
35
4.70
5.22
1.4
1.3
—
—
—
0
0
226
1771
1.54
4.92
4.6
3.5
0.05
0.00
estimate
0.49
58
354
227
1781
1.53
4.91
6.1
4.7
0.00
0.00
estimate
-0.00
53
331
64
363
1.88
4.84
2.6
2.7
1.86
1.80
%
0.23
56
333
228
1799
1.52
4.75
4.5
3.5
0.00
0.01
estimate
0.50
53
318
126
871
1.61
4.73
3.0
2.2
3.07
3.04
mg/l
0.04
105
749
335
2881
1.58
4.62
5.2
4.0
14.72
14.61
pmol/l
0.32
312
2649
149
1077
1.56
4.61
2.8
2.5
50.86
61.62
u/l
1.54
137
1004
29
123
2.45
4.58
2.3
2.0
0.88
3.56
ug/l
0.64
20
113
49
259
2.00
4.56
2.1
2.6
81.68
72.56
e9/l
0.88
31
197
83
519
1.73
4.56
3.1
2.3
12.32
13.51
umol/l
0.65
78
485
112
759
1.63
4.54
1.6
1.5
19.52
21.43
nmol/l
0.59
97
653
19
65
3.00
4.49
2.8
4.1
—
—
—
0
0
55
305
1.91
4.46
1.5
1.4
—
—
—
0
0
41
205
2.10
4.43
3.1
2.2
—
—
—
0
0
7
6
11.82
4.29
1.3
1.0
4.92
5.68
mg/g
—
7
6
74
457
1.74
4.24
1.6
1.4
—
—
—
0
0
20
74
2.78
4.14
2.7
3.7
5.31
5.01
kpa
1.05
20
74
20
74
2.78
4.14
2.7
3.7
8.66
8.83
kpa
0.17
20
74
119
835
1.57
4.14
4.2
3.4
—
—
—
0
0
10
18
5.65
3.99
2.7
3.3
639.10
670.00
u/ml
—
10
18
8
11
7.38
3.87
1.3
1.1
138.25
181.18
mmol/24h
—
8
11
427
3962
1.91
3.81
20.6
11.3
—
—
—
0
0
192
1513
1.46
3.77
2.2
2.0
—
—
—
0
0
383
3454
1.61
3.77
5.8
4.6
1.69
2.21
mu/l
0.86
359
3178
154
1165
1.48
3.72
2.9
3.2
2.35
2.36
mmol/l
0.18
136
1042
46
256
1.88
3.71
3.1
4.5
0.00
0.16
%
0.91
15
79
172
1332
1.46
3.68
2.3
1.8
96.71
95.63
pmol/l
0.10
85
682
32
157
2.11
3.65
1.2
1.3
0.18
3.07
u/ml
—
6
9
185
1457
1.45
3.61
4.0
3.2
5.94
5.93
ph
—
9
129
8
13
6.24
3.51
2.5
2.5
—
—
—
0
0
47
269
1.83
3.48
3.1
4.5
0.00
0.11
%
2.17
16
91
130
965
1.48
3.41
4.1
3.5
—
—
—
0
0
159
1229
1.45
3.38
3.4
3.2
28.53
31.11
u/l
0.79
150
1172
36
191
1.96
3.35
7.5
5.3
—
—
—
0
0
24
109
2.27
3.31
1.2
1.8
10.64
10.41
g/l
0.10
19
100
78
524
1.59
3.23
1.3
1.4
992.00
452.90
titre
—
10
124
44
254
1.81
3.18
3.1
4.2
0.47
0.58
%
0.22
15
92
185
1484
1.41
3.17
2.7
2.3
74.48
74.95
nmol/l
0.09
163
1343
16
61
2.68
3.16
3.4
3.8
3.52
4.29
e9/l
0.87
16
61
13
40
3.31
3.16
1.4
1.5
—
—
nmol/l
—
0
0
18
74
2.49
3.08
2.2
2.2
138.18
129.13
g/l
1.05
11
53
17
68
2.56
3.07
1.2
1.4
34.96
25.96
u/l
0.57
17
54
122
914
1.45
3.02
1.4
1.3
0.89
1.71
u/ml
0.73
28
241
16
63
2.59
2.98
3.4
4.2
55.62
57.48
%
0.19
16
63
48
291
1.72
2.95
3.2
4.3
0.63
0.90
%
0.63
16
114
12
37
3.30
2.95
3.1
3.2
—
—
—
0
0
118
888
1.44
2.84
2.5
3.1
1137.85
1223.14
ng/l
0.06
97
743
44
264
1.74
2.81
1.2
1.2
222.22
141.07
u/ml
0.27
38
240
49
304
1.68
2.78
5.0
3.7
—
—
—
0
0
30
160
1.94
2.78
2.8
2.8
0.62
0.67
%
0.35
30
160
69
469
1.55
2.72
1.3
1.2
—
—
—
0
0
16
67
2.44
2.66
2.7
2.8
17.33
15.98
%
—
7
32
20
93
2.20
2.65
1.3
1.8
40.29
37.85
g/l
1.53
15
85
85
610
1.48
2.60
3.6
3.2
51.90
297.27
ng/l
2.07
61
436
25
454
0.53
2.59
1.1
1.4
—
—
—
0
0
284
2499
1.35
2.53
4.1
3.5
—
—
—
0
0
30
166
1.86
2.51
2.9
2.8
1.23
1.29
%
0.11
30
166
287
2534
1.34
2.47
4.0
3.1
60.68
42.51
u/l
1.68
271
2400
198
1663
1.33
2.37
3.9
2.7
117.05
102.53
ug/l
0.40
181
1554
6
13
4.66
2.28
1.8
1.5
113.33
67.38
nmol/24h
—
6
13
18
86
2.14
2.25
1.3
1.5
—
—
—
0
0
20
100
2.04
2.24
3.4
2.5
—
—
—
0
0
59
408
1.51
2.17
2.6
3.1
8.94
6.91
umol/l
0.31
50
350
14
61
2.34
2.16
2.0
3.1
—
—
—
0
0
11
250
0.43
2.16
1.4
1.6
—
—
—
0
0
46
301
1.59
2.16
5.7
3.8
—
—
—
0
0
9
31
2.94
2.08
4.0
2.4
—
—
—
0
0
5
10
5.04
2.07
1.0
1.3
—
—
—
0
0
119
946
1.35
2.03
5.1
3.8
0.00
0.01
estimate
0.69
54
327
106
830
1.36
1.99
1.8
1.4
2.20
2.38
g/l
0.47
71
508
41
268
1.58
1.95
2.9
3.5
1.23
1.23
mmol/l
0.10
36
233
8
27
3.00
1.94
1.0
1.0
—
—
—
0
0
15
71
2.15
1.94
4.4
3.2
8.36
7.64
mmol/l
0.29
15
71
14
65
2.19
1.90
1.1
1.2
—
—
—
0
0
128
1042
1.31
1.84
3.4
3.1
7.42
7.93
mmol/l
0.52
106
892
14
66
2.16
1.83
1.2
1.5
0.17
0.33
nmol/l
—
7
50
420
4008
1.48
1.77
14.0
9.5
26.58
25.98
u/l
0.34
411
3872
9
36
2.53
1.75
5.6
1.3
19.44
21.84
ug/l
—
9
36
122
994
1.31
1.74
4.1
3.2
—
—
—
0
0
81
621
1.37
1.73
3.1
2.8
2.45
2.45
mmol/l
0.06
69
544
48
335
1.48
1.72
2.5
2.3
25.66
32.99
u/l
1.68
41
280
87
677
1.35
1.70
1.7
1.7
460.71
434.85
pmol/l
0.39
78
573
6
19
3.18
1.66
1.3
1.2
—
—
—
0
0
27
167
1.65
1.62
4.6
2.1
1197.95
2329.79
u/l
—
8
65
5
14
3.60
1.62
1.0
2.8
97.20
126.47
ug/l
—
5
14
7
26
2.72
1.58
1.1
1.2
—
—
—
0
0
7
26
2.72
1.58
1.9
1.1
—
—
—
0
0
38
258
1.51
1.56
1.4
1.4
—
—
—
0
0
118
1414
0.78
1.56
3.1
2.7
—
—
—
0
0
438
4231
1.57
1.56
33.3
18.4
39.41
40.22
%
1.85
417
4012
438
4231
1.57
1.56
33.1
18.3
90.88
90.61
fl
0.57
438
4182
357
3341
1.29
1.55
5.9
5.2
39.74
39.26
mmol/mol
0.36
334
3133
438
4232
1.56
1.54
33.1
18.3
30.18
30.20
pg
0.08
438
4182
5
15
3.36
1.52
1.4
1.0
—
—
—
0
0
61
457
1.39
1.51
1.9
1.6
—
—
—
0
0
42
294
1.47
1.50
1.2
1.2
97.07
179.77
iu/ml
0.93
15
125
438
4236
1.55
1.48
33.4
18.5
132.98
135.54
g/l
3.39
438
4185
112
922
1.28
1.47
3.2
3.2
1362.97
273.34
mg/l
0.60
68
604
114
941
1.28
1.46
1.5
1.7
1.47
1.37
mmol/l
0.40
98
809
5
16
3.15
1.44
1.0
1.0
—
—
—
0
0
6
22
2.75
1.44
3.0
2.4
—
—
—
0
0
15
81
1.88
1.41
2.4
1.2
—
—
—
0
0
117
974
1.27
1.40
3.6
3.8
4.83
9.45
mg/mmol
1.01
67
609
9
41
2.22
1.37
1.1
1.1
—
—
—
0
0
6
23
2.63
1.37
1.0
1.2
—
—
—
0
0
6
23
2.63
1.37
1.2
1.2
—
—
—
0
0
5
17
2.96
1.36
1.6
5.7
—
—
—
0
0
16
90
1.81
1.34
1.4
1.4
320.75
319.68
ug/g
—
8
52
61
467
1.35
1.34
1.5
1.3
—
—
—
0
0
377
3576
1.28
1.32
4.2
4.1
5.82
5.85
mmol/l
0.17
353
3301
5
18
2.80
1.29
2.0
5.6
—
—
—
0
0
6
25
2.42
1.24
1.0
1.0
272.17
280.25
mg/l
—
6
20
18
109
1.68
1.20
1.1
1.2
—
—
—
0
0
10
50
2.02
1.17
2.8
2.7
3.82
4.05
mmol/l
—
10
50
10
50
2.02
1.17
2.8
2.7
103.60
105.60
mmol/l
—
10
50
105
882
1.25
1.16
2.9
2.6
350.28
7988.45
umol/l
4.47
83
779
5
20
2.52
1.15
6.8
6.4
—
—
—
0
0
40
295
1.39
1.12
1.5
1.4
—
—
—
0
0
8
40
2.02
1.12
1.3
1.3
—
—
—
0
0
8
41
1.97
1.09
1.4
1.9
28.63
32.02
pg
—
8
41
7
32
2.21
1.08
1.0
1.2
—
—
—
0
0
5
109
0.45
1.01
1.0
1.3
—
—
—
0
0
9
49
1.85
0.99
3.0
2.7
—
—
—
0
0
15
92
1.65
0.98
3.1
4.0
—
—
—
0
0
37
280
1.35
0.92
3.9
3.1
—
—
—
0
0
11
63
1.76
0.91
6.5
3.7
—
—
—
0
0
79
663
1.23
0.90
1.3
1.3
23.17
33.59
iu/ml
0.33
19
224
19
274
0.68
0.87
1.2
1.4
—
—
—
0
0
60
490
1.26
0.87
2.3
2.3
99.61
117.99
ug/g
0.31
45
382
8
44
1.83
0.86
2.5
3.9
—
—
—
0
0
24
171
1.43
0.85
3.4
3.1
—
—
—
0
0
8
45
1.79
0.84
2.5
2.5
—
—
—
0
0
27
198
1.39
0.82
2.7
2.8
0.20
0.14
e6/l
0.30
27
191
6
32
1.89
0.82
1.3
1.2
—
—
—
0
0
17
114
1.51
0.80
4.5
1.8
—
—
—
0
0
17
114
1.51
0.80
1.2
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.5
—
37.63
—
0
19
20
143
1.42
0.71
1.5
1.2
—
—
—
0
0
9
59
1.54
0.68
2.0
4.0
—
—
—
0
0
9
59
1.54
0.68
1.1
1.1
—
—
—
0
0
15
103
1.47
0.65
3.5
2.5
—
—
—
0
0
11
70
1.59
0.65
1.2
1.7
—
—
—
0
0
11
70
1.59
0.65
1.1
1.1
—
—
—
0
0
7
44
1.60
0.65
1.3
1.9
—
—
—
0
0
5
29
1.73
0.64
2.0
1.6
1.40
1.00
g/l
—
5
29
38
466
0.80
0.63
1.6
1.5
—
—
—
0
0
10
63
1.60
0.62
1.7
1.3
—
—
—
0
0
75
652
1.18
0.62
1.3
1.3
2.79
12.68
u/ml
2.78
26
255
87
768
1.16
0.60
2.0
1.9
—
—
—
0
0
8
52
1.55
0.59
1.3
1.6
—
—
—
0
0
40
328
1.24
0.59
1.2
1.2
—
—
—
0
0
31
248
1.27
0.57
4.9
2.8
3.96
5.49
e9/l
0.57
25
211
11
74
1.50
0.54
1.2
1.1
—
13.02
—
0
5
29
233
1.26
0.52
1.2
1.2
—
—
—
0
0
9
65
1.39
0.51
1.4
1.8
—
—
—
0
0
26
207
1.27
0.50
1.4
1.2
—
—
—
0
0
18
136
1.34
0.50
4.7
1.4
—
—
—
0
0
14
102
1.38
0.48
3.1
2.4
9.47
12.01
mg/l
0.87
14
96
12
85
1.42
0.47
6.2
1.5
—
—
—
0
0
45
385
1.19
0.46
1.9
1.5
—
—
—
0
0
7
49
1.43
0.46
1.6
1.6
—
—
—
0
0
5
31
1.62
0.43
1.6
1.2
—
—
—
0
0
5
34
1.48
0.40
1.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
88
804
1.12
0.39
4.3
3.6
1.02
1.02
kg/l
1.19
11
108
36
418
0.85
0.38
1.6
1.7
—
—
—
0
0
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
11
81
1.37
0.36
1.5
1.3
—
—
—
0
0
6
46
1.31
0.33
2.5
3.3
—
—
—
0
0
114
1067
1.09
0.32
1.4
1.5
—
—
—
0
0
19
156
1.23
0.31
1.8
1.6
—
—
—
0
0
44
392
1.14
0.30
1.3
1.3
—
—
—
0
0
46
412
1.13
0.29
1.7
1.7
—
—
—
0
0
20
168
1.20
0.27
4.5
1.4
—
—
—
0
0
20
168
1.20
0.27
2.6
2.3
—
—
—
0
0
50
550
0.90
0.27
3.2
2.8
0.87
0.78
ug/l
0.34
35
358
30
341
0.87
0.26
2.8
4.2
9.75
40.80
ug/l
0.68
24
276
68
628
1.10
0.26
2.0
1.6
—
—
—
0
0
5
73
0.68
0.26
1.4
1.1
—
—
—
0
0
15
123
1.23
0.25
13.3
9.9
—
—
—
0
0
96
904
1.08
0.24
4.2
4.7
2.35
2.63
ug/l
0.26
84
810
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
7.0
—
96.17
—
0
6
0
10
0.00
0.21
0.0
3.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
6
53
1.13
0.18
1.2
1.1
—
—
—
0
0
329
3341
0.95
0.18
29.6
15.8
332.20
332.72
g/l
0.47
329
3318
11
92
1.20
0.16
1.0
1.1
—
—
—
0
0
15
172
0.87
0.16
1.1
1.1
—
—
—
0
0
20
178
1.13
0.15
4.5
1.4
—
—
—
0
0
20
178
1.13
0.15
4.5
1.4
—
—
—
0
0
20
180
1.12
0.13
4.5
1.4
—
—
—
0
0
359
3558
1.04
0.11
3.9
3.7
1.37
1.27
mmol/l
1.15
335
3299
5
48
1.04
0.09
1.0
1.1
1.39
1.44
g/l
—
5
41
6
56
1.07
0.08
1.5
1.7
—
—
—
0
0
12
133
0.90
0.07
1.5
1.6
—
—
—
0
0
6
73
0.82
0.07
1.3
1.1
—
—
—
0
0
14
153
0.91
0.07
1.1
1.3
105.60
255.84
miu/ml
—
5
77
19
177
1.08
0.06
4.7
1.4
—
—
—
0
0
370
3681
1.02
0.05
4.3
4.1
4.67
4.74
mmol/l
0.63
347
3451
369
3672
1.02
0.05
4.3
4.0
1.41
1.49
mmol/l
3.15
343
3424
20
211
0.95
0.04
2.4
2.5
—
—
—
0
0
376
3747
1.02
0.03
4.7
4.5
2.80
2.83
mmol/l
0.22
352
3488
15
144
1.04
0.00
1.1
1.4
—
—
—
0
0
18
181
0.99
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
174.60
—
0
5
0
8
0.00
0.00
0.0
1.3
—
74.94
—
0
8
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
16.36
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
30.80
—
0
5
8
82
0.98
-0.00
2.1
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
3.78
—
0
6
0
6
0.00
-0.00
0.0
6.3
—
—
—
0
0
6
59
1.02
-0.00
8.3
4.1
—
—
—
0
0
9
99
0.91
-0.00
2.1
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_CNSOTH and mortality.

Females

Parameter HR [95% CI] p-value
G6_CNSOTH 2.546 [1.94, 3.33] < 0.001
Birth year 0.999 [0.99, 1.01] 0.811

During the follow-up period (1.1.1998 — 31.12.2019), 160 out of 1017 females with G6_CNSOTH died.

Males

Parameter HR [95% CI] p-value
G6_CNSOTH 2.416 [1.86, 3.13] < 0.001
Birth year 0.99 [0.98, 1.0] 0.03

During the follow-up period (1.1.1998 — 31.12.2019), 195 out of 815 males with G6_CNSOTH died.

Mortality risk

Mortality risk for people of age

years, who have G6_CNSOTH.

N-year risk Females Males
1 0.256% 0.513%
5 1.547% 2.716%
10 3.976% 7.605%
15 7.418% 14.388%
20 12.607% 23.066%

Relationships between endpoints

Index endpoint: G6_CNSOTH – Other disorders of central nervous system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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