No definition available.
Acquired clawhand, clubhand, clawfoot and clubfoot
M13_CLAWCLUBHANDFOOT
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
199 |
4. Check minimum number of eventsNone |
199 |
5. Include endpointsNone |
199 |
6. Filter based on genotype QC (FinnGen only) |
195 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M21
- Name in latin
- Deformitas [acquisita] manus sive pedis, typus talipes
Similar endpoints
↥List of similar endpoints to
Acquired clawhand, clubhand, clawfoot and clubfoot
based on the number of shared cases.
Similar with more cases:
- Other joint disorders
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1250 | 679 | 569 |
| Only index persons | 1221 | 666 | 555 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 48.01 | 49.30 | 46.45 |
| Only index persons | 47.95 | 49.50 | 46.08 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 195 | 116 | 79 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 51.57 | 50.49 | 53.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 199
- Matched controls
- 1990
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M21.5
ICD-10 Finland
Acquired clawhand, clubhand, clawfoot and clubfoot
+∞
288.1
199
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
38.9
106.6
71
28
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
27.9
82.4
61
31
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
20.0
73.3
64
46
M19.0
ICD-10 Finland
Primary arthrosis of other joints
34.0
64.4
43
16
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
22.1
61.2
49
29
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
+∞
59.4
54
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
+∞
52.4
48
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
19.3
41.0
34
21
L16
ICPC
Ankle symptom/complaint
8.0
37.4
62
106
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
431.3
37.3
36
*
WX320
NOMESCO Finland
Spinalanesthesy
6.5
34.3
74
165
M25.5
ICD-10 Finland
Pain in joint
5.9
33.4
88
235
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
126.4
30.7
32
*
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
12.2
30.6
33
32
NH3EA
NOMESCO Finland
Feet X-ray examination with load
182.4
30.6
31
*
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
+∞
28.9
27
*
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
168.7
28.5
29
*
N03AX12
ATC
[U] gabapentin; oral
6.2
28.4
60
129
B01AB05
ATC
enoxaparin; parenteral
5.1
28.3
92
288
L17
ICPC
Foot/toe symptom/complaint
5.0
27.5
93
299
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
310.7
27.4
27
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
10.9
26.0
30
32
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
10.9
26.0
30
32
WX702
NOMESCO Finland
Supraglottic ventilation device
8.9
25.0
34
45
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
34.3
25.0
32
11
SPAT1229
SPAT
Assessment of need for aid
9.3
24.6
32
40
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
+∞
24.5
23
*
NHG22
NOMESCO Finland
Fusion of subtalar joint
+∞
23.4
22
*
WX725
NOMESCO Finland
Noninvasive ventilation
8.4
23.2
33
46
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
258.5
23.1
23
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.3
23.1
58
144
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
25.1
23.0
32
15
TQW40
NOMESCO Finland
Remowal of suture of skin
8.1
21.9
32
46
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
5.5
21.2
48
108
NHM10
NOMESCO Finland
Fasciotomy of ankle or foot
85.9
21.2
23
*
Q66.0
ICD-10 Finland
Talipes equinovarus
233.4
21.0
21
*
TPH04
NOMESCO Finland
Cathetrisation of vein
4.4
20.9
70
217
B01AB10
ATC
tinzaparin; parenteral
6.4
20.4
38
71
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.9
20.2
110
479
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
20.1
19
*
WX720
NOMESCO Finland
Own respiration
8.9
19.6
26
33
WX704
NOMESCO Finland
Intubation
6.0
19.5
39
78
M77.4
ICD-10 Finland
Metatarsalgia
7.3
19.5
31
49
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
61.4
19.4
22
*
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
58.3
18.3
21
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
7.9
18.3
27
39
Z01.8
ICD-10 Finland
Other specified special examinations
4.0
18.3
70
237
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
5.5
18.2
40
87
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
18.0
17
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.9
17.5
70
243
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
38.8
17.0
21
6
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
16.9
16
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.1
16.7
32
61
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
52.2
16.3
19
*
N02AJ06
ATC
codeine and paracetamol; systemic
3.4
16.0
102
474
M16.1
ICD-10 Finland
Other primary coxarthrosis
24.5
15.9
22
10
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
15.8
15
*
M19.2
ICD-10 Finland
Other secondary arthrosis
+∞
15.8
15
*
Q66.7
ICD-10 Finland
Pes cavus
92.5
15.8
17
*
SPAT1153
SPAT
Removal of sutures
3.4
15.3
78
314
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
12.3
14.5
26
24
X59
ICD-10 Finland
Exposure to unspecified factor
3.8
14.1
53
174
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.6
13.7
37
95
NHL20
NOMESCO Finland
Myotomy or tenotomy of foot
+∞
13.7
13
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.3
13.4
71
289
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
43.3
13.4
16
*
N02AX02
ATC
tramadol; systemic, rectal
3.0
13.2
93
446
NHL30
NOMESCO Finland
Suture or reinsertion of tendon of foot
30.8
13.2
17
6
N03AX16
ATC
[U] pregabalin
3.5
13.0
56
200
M01AH05
ATC
etoricoxib; oral
3.2
13.0
140
847
G56.0
ICD-10 Finland
Carpal tunnel syndrome
4.3
12.8
37
100
M20.1
ICD-10 Finland
Hallux valgus (acquired)
18.9
12.8
19
11
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
138.4
12.6
13
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
12.2
12.4
22
20
L15
ICPC
Knee symptom/complaint
3.5
12.4
51
177
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.8
12.4
24
46
NH1AD
NOMESCO Finland
Ankle and foot CT
23.1
12.2
17
8
M79.6
ICD-10 Finland
Pain in limb
2.9
11.9
95
482
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
69.1
11.7
13
*
ZXA00
NOMESCO Finland
Right side
3.2
11.3
57
223
M67.0
ICD-10 Finland
Short Achilles tendon (acquired)
46.0
11.1
13
*
M01AH01
ATC
celecoxib; oral
3.7
11.0
40
127
L28
ICPC
Limited function/disability (L)
3.8
10.8
37
113
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
5.0
10.6
24
53
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
+∞
10.5
10
*
NHG20
NOMESCO Finland
Fusion of talocrural joint
+∞
10.5
10
*
L08
ICPC
Shoulder symptom/complaint
3.1
10.3
51
197
S93.4
ICD-10 Finland
Sprain and strain of ankle
3.6
10.1
38
123
B01AF01
ATC
rivaroxaban; oral
5.0
10.1
23
51
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
21.4
10.0
14
7
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
7.6
9.6
22
32
WX400
NOMESCO Finland
Inhalation anesthesy
5.1
9.5
21
45
WX111
NOMESCO Finland
Local infiltration anesthesia
+∞
9.4
9
*
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
+∞
9.4
9
*
M20.5
ICD-10 Finland
Other deformities of toe(s) (acquired)
+∞
9.4
9
*
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
14.6
9.3
15
11
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
9.2
48
190
NHE15
NOMESCO Finland
Suture or reinsertion of ligament of ankle
38.6
9.1
11
*
UKC02
NOMESCO Finland
Cystoscopy
3.4
9.0
35
116
ZXD20
NOMESCO Finland
Day surgery
3.6
8.8
32
101
A46
ICD-10 Finland
Erysipelas
3.4
8.8
36
123
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
52.3
8.8
10
*
G60.0
ICD-10 Finland
Hereditary motor and sensory neuropathy
52.3
8.8
10
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
8.7
92
517
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
17.3
8.7
13
8
SAA02
NOMESCO Finland
Basic examination of mouth
2.7
8.6
152
1076
A02BC05
ATC
esomeprazole; systemic
2.4
8.5
87
480
75400
ICD-8 Finland
Clubfoot (congenital), Pes equino-varus adductus
93.9
8.5
9
*
WX213
NOMESCO Finland
Lower leg blockade
93.9
8.5
9
*
N06AX21
ATC
duloxetine; oral
3.5
8.4
32
104
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.3
8.4
23
59
N02BF01
ATC
gabapentin; oral
4.3
8.4
23
59
7545B
ICD-9 Finland
Certain congenital musculoskeletal deformities, Varus deformities of feet[TALIPES EQUINOVARUS CONGENITUS]
+∞
8.4
8
*
NHG82
NOMESCO Finland
Fusion of other tarsal joint
+∞
8.4
8
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
15.3
8.3
13
9
Z3229
NOMESCO Finland
Other healthcare associate professional
4.4
8.3
22
55
A02BC03
ATC
lansoprazole; oral
2.6
8.3
63
302
N02BE01
ATC
paracetamol; systemic, rectal
4.3
8.3
183
1448
L84
ICD-10 Finland
Corns and callosities
9.6
8.2
16
18
S92.3
ICD-10 Finland
Fracture of metatarsal bone
7.1
8.1
19
29
L13
ICPC
Hip symptom/complaint
3.2
8.1
36
129
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.7
8.0
55
250
L03
ICPC
Low back symptom/complaint
2.5
8.0
63
307
M21.6
ICD-10 Finland
Other acquired deformities of ankle and foot
46.9
7.8
9
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
7.7
63
311
M01AE03
ATC
ketoprofen; systemic, rectal
2.4
7.7
78
425
NE1AA
NOMESCO Finland
Pelvis X-ray examination
9.4
7.7
15
17
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.4
7.6
29
94
WX110
NOMESCO Finland
Infiltration anesthesia
2.7
7.6
157
1160
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
83.1
7.5
8
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
8.9
7.5
15
18
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
9.9
7.4
14
15
M70.6
ICD-10 Finland
Trochanteric bursitis
3.4
7.4
29
96
WZA00
NOMESCO Finland
Concise certificate
4.6
7.4
18
42
M76.6
ICD-10 Finland
Achilles tendinitis
4.6
7.4
18
42
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
7.3
7
*
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
4.1
7.3
21
56
WX002
NOMESCO Finland
Sedation and analgesia
2.9
7.2
38
150
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
31.3
7.2
9
*
ZA7.0
ICD-10 Finland
Ankle and foot
20.9
7.2
10
5
M19.8
ICD-10 Finland
Other specified arthrosis
12.7
7.2
12
10
UJF32
NOMESCO Finland
Coloscopy
2.5
7.2
54
256
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.9
7.1
36
139
ACC51
NOMESCO Finland
Release of median nerve
4.3
7.1
19
48
A10AB01
ATC
insulin (human); parenteral
7.1
7.0
16
24
M54.5
ICD-10 Finland
Low back pain
2.3
7.0
73
401
L29
ICPC
Musculoskeletal sympt/complt other
3.7
6.9
23
68
S18
ICPC
Laceration/cut
2.2
6.9
89
532
H04AA01
ATC
glucagon; nasal, parenteral
9.8
6.9
13
14
W00
ICD-10 Finland
Fall on same level involving ice and snow
3.3
6.9
28
95
X58
ICD-10 Finland
Exposure to other specified factors
2.9
6.8
34
130
L88
ICPC
Rheumatoid/seropositive arthritis
17.4
6.8
10
6
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
41.5
6.8
8
*
M67.8
ICD-10 Finland
Other specified disorders of synovium and tendon
23.4
6.7
9
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.5
6.7
50
236
SPAT1301
SPAT
No procedures
2.3
6.6
64
338
ZXA05
NOMESCO Finland
Left side
2.6
6.6
46
209
S93.2
ICD-10 Finland
Rupture of ligaments at ankle and foot level
10.6
6.6
12
12
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.6
6.5
22
66
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
7.0
6.5
15
23
A07EC01
ATC
sulfasalazine; oral, rectal
7.0
6.5
15
23
S15
ICPC
Foreign body in skin
5.9
6.5
17
31
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
72.1
6.5
7
*
NHL50
NOMESCO Finland
Tenolysis or tenosynovectomy of foot
72.1
6.5
7
*
M66.4
ICD-10 Finland
Spontaneous rupture of other tendons
72.1
6.5
7
*
M24.2
ICD-10 Finland
Disorder of ligament
72.1
6.5
7
*
N99
ICPC
Neurological disease other
72.1
6.5
7
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.0
6.4
31
116
M03BX01
ATC
baclofen; systemic
11.6
6.4
11
10
M01AX05
ATC
glucosamine; oral
3.5
6.4
23
72
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.3
6.3
25
83
S97
ICPC
Chronic ulcer skin
4.2
6.3
17
43
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.2
6.3
17
43
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
6.3
52
256
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
+∞
6.3
6
*
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
6.3
6
*
WX210
NOMESCO Finland
Plexus blockade of nervus ichiadicus
27.6
6.3
8
*
W19
ICD-10 Finland
Unspecified fall
3.3
6.2
24
79
A02BC01
ATC
omeprazole; systemic
2.3
6.1
54
274
M01AH02
ATC
rofecoxib; oral
3.3
6.0
24
80
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
7.6
6.0
13
18
A10AA01, ,
ATC
7.6
6.0
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
137
819
3.16
12.98
5.3
5.0
6.56
6.59
mmol/l
0.05
125
756
109
580
2.94
12.68
13.7
9.2
1.14
1.18
inr
0.20
30
180
117
649
2.95
12.56
2.9
2.5
—
—
—
0
0
51
195
3.17
10.45
1.5
1.6
1058.84
1193.82
nmol/l
0.43
38
156
64
305
2.62
8.57
1.7
1.6
0.61
1.00
mg/l
2.34
52
229
157
1134
2.82
8.48
8.9
7.3
76.60
76.58
u/l
0.00
152
1072
105
647
2.32
7.81
9.2
8.0
1.22
1.22
mmol/l
0.09
88
568
147
1066
2.45
7.22
5.8
3.2
11.72
10.01
mm/h
0.83
140
979
85
498
2.23
6.93
3.4
3.1
31.39
38.44
ng/l
0.29
59
311
92
560
2.20
6.79
7.9
4.9
35.61
36.41
g/l
0.73
85
526
80
464
2.21
6.63
2.8
2.4
52.34
65.03
u/l
0.63
74
432
43
192
2.58
6.41
1.3
1.1
32.62
1.52
u/ml
0.78
15
89
92
583
2.08
5.91
6.9
6.7
1.22
1.22
mmol/l
0.11
81
543
22
72
3.31
5.69
5.9
3.8
1.41
1.59
mmol/l
0.08
14
62
112
770
2.04
5.69
6.5
6.7
9.40
10.82
umol/l
1.53
105
742
91
584
2.03
5.56
2.9
2.2
76.62
74.18
nmol/l
0.34
84
533
43
205
2.40
5.54
1.9
1.9
—
—
—
0
0
154
1206
2.22
5.33
4.6
3.8
14.67
14.60
pmol/l
0.16
139
1128
176
1464
2.75
5.23
5.8
4.3
1.80
2.68
mu/l
0.56
164
1365
81
511
1.99
5.10
2.4
1.8
108.65
95.35
pmol/l
1.18
40
281
184
1574
3.24
5.02
18.9
11.3
19.29
23.70
mg/l
1.30
163
1166
58
326
2.10
5.00
3.7
2.4
325.21
9395.66
umol/l
2.02
52
296
41
201
2.31
4.94
1.4
1.2
19.06
13.62
iu/ml
0.32
14
73
52
292
2.06
4.44
1.5
1.4
19.43
20.28
nmol/l
0.18
46
251
36
175
2.29
4.40
5.8
3.5
30.92
30.71
%
0.04
26
125
54
315
1.98
4.13
2.7
3.1
1405.45
1012.20
ng/l
0.29
48
272
66
416
1.88
4.00
5.1
3.7
34.40
9.97
mg/mmol
0.66
39
276
52
303
1.97
3.98
2.6
1.7
2.45
2.97
mg/l
0.97
44
255
145
1166
1.90
3.91
4.0
2.9
39.01
42.38
u/l
0.43
136
1115
58
353
1.91
3.90
1.3
1.2
1.42
2.63
u/ml
0.41
12
99
47
272
1.95
3.65
1.4
1.6
473.13
30932654.47
pmol/l
0.50
39
236
41
232
1.97
3.38
3.3
3.9
0.81
0.82
mmol/l
0.24
36
226
8
14
5.90
3.37
1.5
1.3
—
—
—
0
0
29
144
2.19
3.36
1.9
1.7
—
—
—
0
0
31
160
2.11
3.27
3.1
2.1
25.50
23.53
%
0.33
22
136
7
11
6.55
3.21
1.0
1.0
—
—
—
0
0
13
44
3.09
3.20
1.5
1.8
37.62
38.07
nmol/l
0.02
13
44
15
57
2.76
3.04
1.0
1.0
—
10.98
—
0
8
27
138
2.11
2.92
8.3
12.3
2.74
1.40
mmol/l
0.62
17
112
10
28
3.70
2.82
4.9
1.9
8.00
7.97
kpa
—
10
28
27
141
2.06
2.77
1.9
1.7
—
—
—
0
0
32
179
1.94
2.72
2.9
2.0
2.26
2.34
g/l
0.51
27
166
14
55
2.66
2.68
2.2
2.2
—
—
—
0
0
74
533
1.62
2.63
5.9
3.0
26.52
30.54
u/l
1.39
67
511
7
15
4.79
2.62
1.1
1.6
—
—
—
0
0
7
15
4.79
2.62
1.1
1.6
—
—
—
0
0
7
15
4.79
2.62
1.1
1.5
—
—
—
0
0
8
21
3.92
2.49
2.0
2.1
12.88
12.85
%
—
8
21
8
22
3.74
2.39
1.4
1.3
—
—
—
0
0
43
280
1.68
2.23
3.3
3.9
9.00
333.44
ng/l
2.32
30
201
10
36
2.87
2.17
1.8
1.6
—
—
—
0
0
7
19
3.78
2.17
1.6
1.3
625.14
377.68
pmol/l
—
7
19
7
19
3.78
2.17
1.1
1.2
—
—
—
0
0
7
19
3.78
2.17
1.1
1.4
—
—
—
0
0
107
872
1.49
2.05
8.5
9.7
4.24
4.04
e9/l
0.41
93
759
8
27
3.04
1.96
1.3
1.9
—
—
—
0
0
8
27
3.04
1.96
1.3
1.9
—
—
—
0
0
6
16
3.83
1.95
1.0
1.1
—
—
—
0
0
7
22
3.26
1.90
1.1
1.2
—
—
—
0
0
7
22
3.26
1.90
1.0
1.5
—
41.86
—
0
5
7
22
3.26
1.90
1.1
1.5
—
—
—
0
0
8
28
2.93
1.88
3.9
2.0
25.26
24.21
mmol/l
—
8
28
164
1476
1.63
1.87
7.5
4.8
40.94
39.08
mmol/mol
1.21
158
1390
7
23
3.12
1.81
2.7
1.7
130.57
130.63
g/l
—
7
16
173
1585
1.70
1.75
4.4
3.6
1.34
1.31
mmol/l
0.24
163
1484
12
55
2.26
1.71
2.0
1.9
—
—
—
0
0
86
690
1.43
1.70
3.2
2.5
111.61
112.99
ug/l
0.02
81
645
7
25
2.86
1.66
1.7
1.5
—
—
—
0
0
8
32
2.56
1.61
1.3
1.7
—
—
—
0
0
88
716
1.41
1.58
3.7
2.9
0.00
0.00
estimate
-0.00
17
130
5
15
3.39
1.53
2.2
2.0
—
—
—
0
0
178
1656
1.71
1.53
5.2
3.9
4.65
4.77
mmol/l
0.91
168
1561
9
39
2.37
1.45
1.2
1.2
—
—
—
0
0
54
408
1.44
1.44
2.0
1.7
1.49
1.43
mmol/l
0.16
46
339
9
42
2.20
1.35
2.0
1.4
—
—
—
0
0
130
1151
1.37
1.31
3.1
3.2
—
—
—
0
0
8
35
2.34
1.28
1.3
1.7
—
—
—
0
0
9
45
2.05
1.25
1.6
1.5
—
—
—
0
0
169
1572
1.50
1.23
4.7
3.9
5.89
5.83
mmol/l
0.21
158
1462
5
19
2.67
1.22
1.0
1.3
—
—
—
0
0
8
40
2.04
1.13
1.0
1.0
—
—
—
0
0
178
1680
1.56
1.13
5.7
4.3
2.73
2.88
mmol/l
1.33
166
1578
16
97
1.71
1.10
1.9
1.6
—
—
—
0
0
8
41
1.99
1.10
3.5
2.9
—
—
—
0
0
175
1649
1.51
1.08
5.2
3.9
1.46
1.45
mmol/l
0.07
165
1545
42
320
1.40
1.07
2.6
2.3
—
—
—
0
0
12
68
1.81
1.03
1.2
1.7
—
—
—
0
0
57
460
1.34
1.02
2.2
3.8
2.35
2.37
mmol/l
0.66
48
418
0
30
0.00
0.98
0.0
1.6
—
—
—
0
0
85
730
1.29
0.96
3.8
2.9
0.00
0.00
estimate
-0.00
17
115
84
721
1.29
0.95
4.9
4.1
0.00
0.00
estimate
-0.00
18
120
6
30
2.03
0.87
1.2
1.8
—
—
—
0
0
16
104
1.59
0.87
2.1
1.2
58.79
148.67
u/ml
2.43
16
92
13
82
1.63
0.80
1.4
1.4
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
27
0.00
0.78
0.0
1.2
—
—
—
0
0
19
133
1.47
0.77
1.2
1.2
219.29
141.80
iu/ml
—
7
58
9
54
1.70
0.75
1.8
3.2
28.32
51.28
%
—
9
54
7
38
1.87
0.74
1.0
4.9
22.37
40.54
mg/l
—
7
33
7
38
1.87
0.74
1.0
4.9
21.14
43.68
mg/l
—
7
33
67
576
1.25
0.72
4.2
2.9
—
—
—
0
0
45
370
1.28
0.70
4.8
3.1
0.00
0.01
estimate
0.50
15
118
7
42
1.69
0.69
1.0
1.2
—
—
—
0
0
21
154
1.41
0.68
6.9
5.5
—
—
—
0
0
15
207
0.70
0.60
2.0
1.7
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
43
360
1.25
0.58
3.7
3.8
20.16
20.21
%
0.01
17
155
52
446
1.22
0.57
5.1
4.2
1.50
2.11
ug/l
1.01
47
409
6
37
1.64
0.56
1.2
1.4
—
—
—
0
0
6
40
1.52
0.52
1.7
1.8
—
—
—
0
0
6
40
1.52
0.52
1.3
1.3
—
—
—
0
0
36
305
1.22
0.45
1.8
1.4
—
—
—
0
0
6
94
0.63
0.43
2.0
1.8
7.98
3.05
mg/l
—
6
69
160
1540
1.20
0.42
13.4
10.2
85.03
86.37
ml/min/173m2
0.27
127
1274
0
15
0.00
0.41
0.0
3.7
—
977.47
—
0
15
13
97
1.36
0.40
6.5
3.0
1.22
1.23
mmol/l
0.30
13
86
0
18
0.00
0.40
0.0
2.5
—
—
—
0
0
5
36
1.40
0.38
1.8
1.8
—
—
—
0
0
18
223
0.79
0.38
2.3
2.3
—
—
—
0
0
8
65
1.24
0.27
1.4
3.5
26.40
24.82
mmol/l
—
8
65
8
66
1.22
0.27
1.4
1.4
—
—
—
0
0
19
160
1.21
0.26
3.1
7.4
102.53
104.13
mmol/l
0.48
19
160
15
123
1.24
0.26
3.1
3.0
—
—
—
0
0
53
488
1.12
0.25
4.4
2.7
—
—
—
0
0
9
77
1.18
0.24
1.7
1.8
—
—
—
0
0
20
232
0.85
0.24
2.4
2.4
1.12
1.02
e6/l
—
10
119
24
272
0.87
0.22
3.0
2.4
0.80
0.79
ug/l
0.02
11
159
0
11
0.00
0.21
0.0
4.9
—
116.64
—
0
11
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
485.33
—
0
6
0
10
0.00
0.21
0.0
3.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
5
43
1.17
0.21
1.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
9
115
0.77
0.20
1.9
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
18.05
—
0
14
32
292
1.11
0.17
1.5
1.4
—
—
—
0
0
20
219
0.90
0.11
2.7
2.5
3.00
2.12
e6/l
0.20
11
106
35
372
0.93
0.11
4.2
2.6
0.10
0.42
e6/l
2.05
29
264
7
67
1.05
0.08
1.6
1.6
226.14
326.58
mu/l
—
7
62
19
198
0.96
0.02
1.9
2.2
—
—
—
0
0
14
146
0.96
0.00
4.8
4.4
2.51
10.71
ug/l
—
9
127
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.8
—
17.83
—
0
8
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
9
90
1.00
0.00
1.2
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
8
87
0.92
-0.00
1.1
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
16.69
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.7
—
—
—
0
0
5
55
0.91
-0.00
1.8
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_CLAWCLUBHANDFOOT and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have M13_CLAWCLUBHANDFOOT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: M13_CLAWCLUBHANDFOOT – Acquired clawhand, clubhand, clawfoot and clubfoot
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data