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R13

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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Complicated migraine, drug-induced

Endpoint Browser

COMPLICATED_MIGRAINE

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ATC codes for adverse effects of Drugs — ANY
  • Hospital discharge: ICD-10 — G43.3#

1 out of 7 registries used, show all original rules.

40

4. Check minimum number of events

None

40

5. Include endpoints

None

40

6. Filter based on genotype QC (FinnGen only)

38

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

All Female Male
Number of individuals 38 28 10
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 39.49 35.27 51.32

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
348
+∞
2.07
17.0
12.4
20.22
19.36
mg/l
0.05
31
262
7
23
3.46
1.90
1.1
1.2
—
—
—
0
0
17
99
2.25
1.60
2.9
2.2
105.41
106.57
u/l
0.02
17
94
5
119
0.34
1.59
1.0
1.4
—
—
—
0
0
13
74
2.12
1.25
2.1
1.8
1.01
1.24
mg/l
0.13
13
57
7
32
2.43
1.15
1.9
1.1
—
—
—
0
0
5
22
2.45
1.06
1.0
1.3
—
—
—
0
0
0
28
0.00
1.02
0.0
3.7
—
—
—
0
0
11
65
1.95
0.94
5.8
4.7
—
—
—
0
0
8
47
1.87
0.87
2.0
1.4
—
—
—
0
0
6
104
0.50
0.75
2.3
3.2
—
—
—
0
0
10
147
0.57
0.72
19.1
8.7
0.00
0.00
e9/l
—
10
122
27
223
1.65
0.68
3.7
3.8
—
—
—
0
0
5
28
1.89
0.68
1.4
1.4
—
—
—
0
0
24
194
1.59
0.65
5.6
3.8
6.25
6.43
mmol/l
0.15
24
180
20
155
1.58
0.65
2.8
2.7
96.94
69.91
ug/l
0.74
20
148
0
20
0.00
0.62
0.0
1.1
—
—
—
0
0
0
20
0.00
0.62
0.0
2.2
—
2846.41
—
0
8
17
128
1.57
0.62
4.0
3.2
19.33
36.06
ng/l
—
6
78
0
22
0.00
0.61
0.0
3.1
—
2.29
—
0
17
11
77
1.59
0.52
2.2
3.5
—
—
—
0
0
0
15
0.00
0.42
0.0
1.1
—
—
—
0
0
11
143
0.68
0.41
2.5
1.8
—
—
—
0
0
0
17
0.00
0.41
0.0
3.1
—
—
—
0
0
40
382
+∞
0.41
23.2
18.2
30.27
30.35
pg
0.13
40
375
40
382
+∞
0.41
23.3
18.4
242.07
256.83
e9/l
0.84
40
374
40
382
+∞
0.41
23.3
18.3
4.55
4.46
e12/l
0.59
40
372
40
382
+∞
0.41
22.8
18.1
38.20
40.08
%
0.51
40
361
40
382
+∞
0.41
23.4
18.3
6.39
6.75
e9/l
0.57
40
373
40
382
+∞
0.41
23.3
18.3
90.53
90.90
fl
0.25
40
375
40
382
+∞
0.41
23.3
18.4
137.30
134.94
g/l
0.49
40
375
13
100
1.44
0.40
2.8
2.3
42.92
54.77
u/l
1.37
13
93
17
143
1.33
0.30
7.6
9.3
1.06
1.18
inr
—
5
48
5
74
0.63
0.29
1.8
1.5
17.20
20.39
nmol/l
—
5
67
15
127
1.29
0.24
3.1
2.6
—
—
—
0
0
9
110
0.77
0.24
3.6
3.0
2.33
2.34
mmol/l
—
9
99
12
143
0.77
0.24
2.4
3.1
—
5.81
—
0
16
5
41
1.25
0.23
1.4
1.3
—
—
—
0
0
13
109
1.29
0.22
4.0
3.8
105.81
42.08
e6/l
—
7
80
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
16.70
—
0
10
0
10
0.00
0.21
0.0
3.8
—
23.68
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
3.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
7.42
—
0
5
35
334
1.38
0.18
4.4
4.1
4.85
4.78
mmol/l
0.18
35
310
35
332
1.43
0.18
4.2
4.1
1.56
1.51
mmol/l
0.21
35
306
10
83
1.27
0.17
2.8
3.3
8.01
7.34
mmol/l
—
10
74
8
98
0.77
0.16
1.5
2.2
—
—
—
0
0
19
172
1.20
0.15
5.4
6.2
11.11
10.38
umol/l
0.19
19
163
14
157
0.83
0.14
11.4
6.0
27.22
28.58
%
0.21
14
152
14
156
0.84
0.13
14.1
6.0
—
—
—
0
0
5
43
1.19
0.10
2.0
2.7
—
—
—
0
0
11
97
1.18
0.10
3.7
3.1
10.68
23.81
e6/l
—
6
77
10
88
1.18
0.09
2.5
2.7
—
—
—
0
0
32
327
0.89
0.08
3.8
4.2
5.88
5.78
mmol/l
0.11
32
301
7
80
0.85
0.08
4.6
7.7
—
—
—
0
0
9
83
1.11
0.08
1.9
3.7
—
—
—
0
0
9
83
1.11
0.08
2.6
1.8
—
—
—
0
0
14
152
0.88
0.08
10.5
5.9
60.06
56.35
%
0.59
14
147
14
152
0.88
0.08
11.4
6.4
7.89
8.43
%
0.43
14
147
32
310
1.16
0.07
4.5
5.0
38.41
38.89
mmol/mol
0.08
32
292
14
150
0.90
0.05
11.2
6.0
2.90
2.61
%
0.22
14
145
16
170
0.90
0.05
10.9
5.9
0.19
0.18
e9/l
0.10
16
155
16
167
0.93
0.02
10.2
5.9
1.96
2.17
e9/l
0.21
16
156
22
227
0.93
0.02
4.1
4.5
—
—
—
0
0
14
146
0.94
0.01
11.2
5.9
0.79
0.68
%
0.32
14
140
16
163
0.97
0.00
9.9
5.8
0.04
0.04
e9/l
0.20
16
148
16
163
0.97
0.00
8.9
5.8
0.52
0.58
e9/l
0.78
16
148
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
83.48
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
4.72
—
0
5
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.7
—
7.13
—
0
7
8
86
0.91
-0.00
2.0
2.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
32
318
1.03
-0.00
3.7
3.7
1.42
1.21
mmol/l
0.36
32
293
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
31.67
—
0
6
0
7
0.00
-0.00
0.0
4.7
—
1.06
—
0
7
0
6
0.00
-0.00
0.0
4.5
—
4.00
—
0
6
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
68
1.04
-0.00
2.1
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
105.50
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

↥

Index endpoint: COMPLICATED_MIGRAINE – Complicated migraine, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).