otitis externa: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
454 |
4. Check minimum number of eventsNone |
454 |
5. Include endpointsNone |
454 |
6. Filter based on genotype QC (FinnGen only) |
438 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H60
- Name in latin
- Cellulitis auris externae
Similar endpoints
↥List of similar endpoints to
Cellulitis of external ear
based on the number of shared cases.
Similar with more cases:
- Otitis externa
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3830 | 1988 | 1820 |
| Only index persons | 3515 | 1861 | 1654 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.05 |
| Only index persons | 0.07 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 41.89 | 39.86 | 44.16 |
| Only index persons | 44.32 | 42.14 | 46.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 438 | 262 | 176 |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | 0.08 |
| Median age at first event (years) | 52.13 | 48.61 | 57.37 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 454
- Matched controls
- 4540
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H60.1
ICD-10 Finland
Cellulitis of external ear
+∞
307.7
454
16
H60.9
ICD-10 Finland
Otitis externa, unspecified
18.3
168.1
156
126
H60.3
ICD-10 Finland
Other infective otitis externa
38.8
131.3
83
26
H60.8
ICD-10 Finland
Other otitis externa
22.4
90.2
69
36
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
216.6
56.4
57
*
H01
ICPC
Ear pain/earache
4.7
42.0
118
314
H60
ICD-10 Finland
Otitis externa
6.7
38.9
67
114
H70
ICPC
Otitis externa
13.5
35.3
34
27
A46
ICD-10 Finland
Erysipelas
4.3
35.1
111
320
H66.0
ICD-10 Finland
Acute suppurative otitis media
4.9
34.7
87
209
H29
ICPC
Ear symptom/complaint other
4.3
30.8
92
253
H04
ICPC
Ear discharge
8.5
27.6
37
47
UDC00
NOMESCO Finland
Ear microscopy
4.7
26.4
67
161
H66.9
ICD-10 Finland
Otitis media, unspecified
4.3
24.4
70
185
J01DB01
ATC
cefalexin; oral
5.0
21.4
420
3237
H60.0
ICD-10 Finland
Abscess of external ear
57.6
19.1
22
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.1
18.0
89
334
H92.0
ICD-10 Finland
Otalgia
4.1
17.8
53
143
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.7
17.4
112
485
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
7.9
17.1
24
32
J01FF01
ATC
clindamycin; systemic
2.4
15.6
151
789
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.5
14.6
115
546
D07AC01
ATC
betamethasone; topical
2.2
13.7
185
1097
J01MA02
ATC
ciprofloxacin; systemic
2.2
13.6
185
1100
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.6
13.6
90
392
S02CA02
ATC
flumetasone and antiinfectives; otic
4.0
13.3
39
104
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
13.1
154
863
H13
ICPC
Plugged feeling ear
2.5
13.1
100
466
H61.8
ICD-10 Finland
Other specified disorders of external ear
33.1
12.6
16
5
H61.2
ICD-10 Finland
Impacted cerumen
3.7
11.8
38
108
Z71.8
ICD-10 Finland
Other specified counselling
2.1
11.8
169
1014
S76
ICPC
Skin infection other
3.6
11.2
39
117
H65.3
ICD-10 Finland
Chronic mucoid otitis media
4.8
11.1
25
54
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
18.4
10.8
16
9
L40.0
ICD-10 Finland
Psoriasis vulgaris
4.0
10.1
29
76
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.6
9.9
24
55
DC1AD
NOMESCO Finland
Temporalbone CT
15.5
9.6
15
10
H65.2
ICD-10 Finland
Chronic serous otitis media
11.8
9.1
16
14
R07.0
ICD-10 Finland
Pain in throat
3.0
9.0
41
146
D05AX52
ATC
calcipotriol, combinations; topical
3.4
8.9
32
98
D05AX02
ATC
calcipotriol; topical
4.1
8.7
24
61
H62.0
ICD-10 Finland
Otitis externa in bacterial diseases classified elsewhere
51.0
8.7
10
*
DFF00
NOMESCO Finland
Pure tone audiometry
2.6
8.6
51
209
D07CC01
ATC
betamethasone and antibiotics; topical
2.3
8.6
68
319
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
8.4
204
1418
H81
ICPC
Excessive ear wax
2.2
8.2
74
366
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.2
7.8
69
339
ZYC01
NOMESCO Finland
Remote contact by phone
2.8
7.7
40
153
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
3.7
7.7
24
67
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
9.1
7.6
15
17
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.2
7.6
69
343
H65.0
ICD-10 Finland
Acute serous otitis media
7.3
7.5
17
24
D07AC13
ATC
mometasone; topical
1.8
7.3
130
817
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
20.4
7.2
10
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
7.1
172
1180
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
6.9
189
1341
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.3
6.8
54
253
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.6
6.8
39
157
H70.0
ICD-10 Finland
Acute mastoiditis
40.7
6.8
8
*
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
40.7
6.8
8
*
Z00.0
ICD-10 Finland
General medical examination
1.9
6.6
95
556
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
6.5
60
300
S01
ICPC
Pain/tenderness of skin
3.2
6.4
25
81
D02AE01
ATC
carbamide; topical
2.7
6.4
33
126
D07XC01
ATC
betamethasone; topical
2.2
6.4
57
281
R42
ICD-10 Finland
Dizziness and giddiness
1.9
6.3
95
563
L03.2
ICD-10 Finland
Cellulitis of face
9.4
6.3
12
13
H02AB06
ATC
prednisolone; systemic
1.7
6.3
201
1475
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
7.2
6.3
14
20
H61.0
ICD-10 Finland
Perichondritis of external ear
+∞
6.3
6
*
L03
ICPC
Low back symptom/complaint
1.7
6.2
127
826
D07AB08
ATC
desonide; topical
2.2
6.2
56
277
J01DA01
ATC
[U] cefalexin
1.6
6.1
272
2161
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.6
6.1
20
58
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
274
2093
1.78
8.05
5.0
4.6
6.53
6.60
mmol/l
0.25
260
1922
209
1531
1.68
6.70
11.3
11.8
1.18
1.18
inr
0.00
69
466
421
3808
2.45
6.08
16.1
12.4
23.12
22.32
mg/l
0.18
371
2957
26
91
2.97
5.88
1.5
1.6
—
—
—
0
0
417
3791
2.23
5.35
16.3
13.8
139.65
139.63
mmol/l
0.04
411
3695
418
3805
2.24
5.32
16.4
13.8
3.96
3.96
mmol/l
0.02
412
3704
324
2756
1.61
4.97
4.7
3.9
11.52
10.64
mm/h
0.56
304
2556
87
540
1.76
4.93
1.9
1.8
—
—
—
0
0
327
2796
1.61
4.83
7.5
7.3
73.76
76.89
u/l
0.74
311
2627
40
194
2.16
4.66
1.6
1.4
—
—
—
0
0
197
1523
1.52
4.49
6.3
6.1
1.20
1.21
mmol/l
1.46
176
1399
261
2151
1.50
4.31
10.8
9.3
4.29
4.02
e9/l
1.32
220
1897
136
980
1.55
4.24
3.1
3.0
0.15
0.42
e6/l
3.18
101
734
166
1265
1.49
3.94
2.8
3.4
29.34
32.47
u/l
0.99
160
1204
382
3451
1.67
3.93
4.7
4.6
1.80
1.86
mu/l
0.40
350
3202
387
3518
1.68
3.76
14.1
11.2
89.85
86.49
ml/min/173m2
2.08
325
2870
224
1822
1.45
3.76
6.9
6.0
28.52
28.69
%
0.08
210
1738
227
1854
1.45
3.71
5.2
6.3
11.11
11.25
umol/l
0.03
213
1764
216
1749
1.45
3.69
2.4
2.6
—
—
—
0
0
165
1269
1.47
3.69
3.8
3.3
29.53
32.80
ng/l
0.15
106
808
92
624
1.59
3.68
3.3
3.4
1315.44
334.23
ng/l
0.63
60
437
41
226
1.89
3.42
2.0
1.6
—
—
—
0
0
219
1797
1.42
3.39
6.7
5.9
57.39
56.77
%
0.35
205
1713
142
1076
1.47
3.38
3.2
3.1
35.29
115.67
e6/l
0.71
108
819
60
375
1.69
3.31
1.8
1.8
—
—
—
0
0
59
368
1.69
3.27
1.8
1.8
—
—
—
0
0
160
1248
1.44
3.24
3.5
3.1
—
—
—
0
0
85
587
1.55
3.13
2.6
2.7
1.15
0.80
e6/l
0.64
48
332
128
976
1.43
2.89
3.4
3.9
16.25
12.15
mg/mmol
0.22
80
626
174
1404
1.39
2.83
4.7
4.9
35.07
36.13
g/l
1.54
162
1321
14
54
2.64
2.73
3.6
5.4
329.64
367.90
umol/l
0.42
14
49
137
1072
1.40
2.65
3.1
3.3
7.32
7.74
mmol/l
0.52
118
931
10
30
3.38
2.61
15.9
14.3
1477.60
1565.83
nmol/l
—
10
30
20
391
0.49
2.60
1.4
1.6
—
—
—
0
0
199
1661
1.35
2.56
7.4
6.9
1.20
1.21
mmol/l
1.82
171
1419
72
507
1.50
2.43
2.9
2.3
2.37
2.37
g/l
0.04
66
465
11
38
2.94
2.43
1.1
1.3
—
—
—
0
0
67
467
1.51
2.37
3.0
2.4
23.15
24.05
%
0.22
62
404
77
553
1.47
2.36
2.8
2.9
3.59
2.49
e6/l
0.42
39
301
125
984
1.37
2.30
2.0
2.1
252.53
273.95
u/l
0.06
116
930
137
1095
1.36
2.29
2.5
2.6
53.38
60.51
u/l
0.83
125
1017
360
3320
1.41
2.28
5.3
5.2
40.37
39.29
mmol/mol
1.12
331
3128
36
219
1.70
2.23
4.1
3.6
1.52
1.36
mmol/l
0.08
27
161
23
122
1.93
2.20
2.1
1.7
—
—
—
0
0
8
24
3.37
2.19
1.6
1.6
63.13
73.42
umol/l
—
8
24
304
2739
1.33
2.17
3.3
3.4
—
—
—
0
0
50
338
1.54
2.05
1.8
2.4
28.49
33.05
u/l
0.80
45
282
56
389
1.50
2.03
7.9
6.9
104.59
104.25
mmol/l
0.26
56
389
31
187
1.71
2.00
1.4
1.5
—
—
—
0
0
110
870
1.35
1.94
2.1
2.3
—
—
—
0
0
44
294
1.55
1.91
8.1
8.6
123.23
119.64
g/l
0.61
44
285
210
1824
1.28
1.86
3.9
3.4
0.00
0.00
estimate
0.50
51
392
49
340
1.49
1.80
8.0
8.3
1.07
1.11
mmol/l
0.03
38
271
71
534
1.39
1.71
2.4
1.7
1.57
1.47
%
0.58
64
475
16
83
1.96
1.66
1.3
1.3
—
—
—
0
0
172
1474
1.27
1.66
2.3
2.3
77.67
75.35
nmol/l
0.47
156
1336
312
2869
1.28
1.65
3.9
4.0
14.72
14.68
pmol/l
0.10
282
2616
108
872
1.31
1.65
1.9
1.6
—
—
—
0
0
418
4016
1.51
1.61
11.1
9.7
27.66
26.89
u/l
0.34
401
3896
208
1833
1.25
1.55
5.1
4.6
0.00
0.00
estimate
-0.00
50
371
439
4271
1.84
1.55
23.6
18.4
259.35
252.51
e9/l
1.48
429
4176
57
421
1.40
1.54
2.4
2.8
4.86
7.59
umol/l
1.31
44
354
6
21
2.88
1.51
1.2
1.5
1.78
1.89
mmol/l
—
6
21
13
65
2.03
1.50
1.2
1.8
—
—
—
0
0
22
132
1.70
1.49
2.5
1.9
—
—
—
0
0
209
1851
1.24
1.47
4.0
3.4
0.00
0.01
estimate
0.50
47
357
439
4276
1.81
1.46
23.7
18.4
4.52
4.53
e12/l
0.28
431
4175
6
22
2.75
1.44
1.2
1.8
—
—
—
0
0
10
46
2.20
1.41
1.1
1.1
—
—
—
0
0
20
119
1.71
1.40
2.8
5.4
2.14
1.62
%
0.85
20
108
11
54
2.06
1.34
1.1
1.3
—
—
—
0
0
438
4272
1.72
1.32
23.8
18.4
40.61
40.46
%
0.23
414
4043
6
24
2.52
1.30
1.0
1.0
—
—
—
0
0
102
845
1.27
1.28
3.3
3.2
818.76
1039.72
ng/l
0.41
88
725
29
196
1.51
1.25
1.6
1.5
24.49
25.33
iu/l
0.05
24
169
9
45
2.02
1.24
1.1
1.1
—
—
—
0
0
16
93
1.75
1.22
1.2
1.3
—
—
—
0
0
21
132
1.62
1.22
1.7
1.6
—
—
—
0
0
28
189
1.51
1.22
8.4
7.1
24.38
24.52
mmol/l
0.07
28
178
152
1325
1.22
1.20
1.9
1.8
95.57
94.48
pmol/l
0.09
67
691
6
26
2.32
1.19
1.0
1.6
—
—
—
0
0
6
26
2.32
1.19
1.2
1.2
—
—
—
0
0
97
807
1.26
1.17
1.5
1.8
0.96
1.15
mg/l
0.59
65
607
8
39
2.07
1.16
1.1
1.1
—
—
—
0
0
5
20
2.52
1.15
3.4
2.8
36220.00
36680.25
ug/l
—
5
20
7
30
2.35
1.12
1.1
1.1
—
—
—
0
0
39
292
1.37
1.02
3.5
4.2
1.93
1.85
mmol/l
0.04
34
233
20
131
1.55
1.01
1.5
1.5
—
—
—
0
0
79
654
1.25
1.00
2.4
2.2
—
—
—
0
0
160
1424
1.19
1.00
4.0
3.4
—
—
—
0
0
52
409
1.31
0.99
4.9
4.0
31.48
31.15
%
0.07
31
281
0
29
0.00
0.98
0.0
2.5
—
0.19
—
0
24
38
286
1.36
0.97
2.7
2.4
69.89
72.69
ml/min/173m2
—
9
115
12
197
0.60
0.96
5.8
2.3
27.19
33.01
u/ml
0.19
12
189
7
37
1.91
0.94
2.1
1.3
—
—
—
0
0
6
27
2.24
0.93
1.0
1.1
—
—
—
0
0
6
28
2.16
0.92
1.3
1.3
—
—
—
0
0
29
211
1.40
0.91
2.3
2.2
1854.12
4050.16
u/l
—
8
86
68
561
1.25
0.90
1.7
1.7
942.10
1209.88
nmol/l
1.84
43
429
102
880
1.21
0.89
2.3
2.1
2.81
2.95
mg/l
0.24
91
758
81
686
1.22
0.85
1.6
1.7
49231231.17
11356375.48
pmol/l
0.34
65
590
49
395
1.27
0.80
5.3
6.9
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
10.58
—
0
19
6
33
1.83
0.79
1.3
1.9
—
—
—
0
0
6
33
1.83
0.79
1.3
1.9
—
—
—
0
0
6
33
1.83
0.79
1.3
1.9
—
—
—
0
0
94
816
1.19
0.77
4.0
3.6
1.02
1.02
kg/l
0.27
16
120
113
997
1.18
0.77
4.7
3.5
0.02
0.01
estimate
0.25
46
361
5
24
2.09
0.74
1.0
1.0
0.94
1.16
u/l
—
5
14
5
24
2.09
0.74
4.6
2.5
—
—
—
0
0
380
3678
1.20
0.74
4.3
4.1
4.55
4.68
mmol/l
1.75
346
3450
6
107
0.55
0.73
2.8
2.5
724.17
341.67
ug/l
—
6
100
7
39
1.81
0.72
1.4
2.0
—
—
—
0
0
7
42
1.68
0.68
1.0
1.1
—
—
—
0
0
5
27
1.86
0.68
2.8
2.3
16.01
18.54
ug/l
—
5
27
5
28
1.79
0.66
2.2
1.3
482.40
14916.55
e6/l
—
5
20
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
10
62
1.63
0.65
1.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
29
1.73
0.64
1.0
1.2
—
—
—
0
0
69
594
1.19
0.63
2.4
2.0
—
—
—
0
0
0
20
0.00
0.60
0.0
7.9
—
33.43
—
0
7
89
787
1.16
0.60
1.7
1.5
20.25
20.38
nmol/l
0.03
75
677
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
41
337
1.24
0.60
3.5
2.9
—
—
—
0
0
16
115
1.41
0.57
1.4
1.6
—
231.43
—
0
7
20
150
1.35
0.57
2.1
2.3
0.61
0.65
%
0.27
20
150
5
90
0.55
0.56
7.0
3.2
37.04
35.72
mg/l
—
5
73
5
90
0.55
0.56
7.2
3.2
179.12
126.77
mg/l
—
5
73
367
3565
1.15
0.56
4.5
4.1
6.05
5.86
mmol/l
1.49
339
3284
6
37
1.63
0.55
1.2
1.1
—
—
—
0
0
9
61
1.48
0.54
1.9
1.9
—
—
—
0
0
9
62
1.46
0.53
1.9
1.6
—
—
—
0
0
16
214
0.74
0.52
1.1
1.4
—
—
—
0
0
272
2603
1.11
0.50
3.2
3.1
43.54
42.54
u/l
0.11
252
2479
18
136
1.34
0.50
1.6
1.4
—
—
—
0
0
362
3522
1.14
0.50
3.9
3.7
1.42
1.27
mmol/l
3.65
329
3276
185
1737
1.11
0.49
3.2
2.8
102.82
109.22
ug/l
0.19
168
1616
7
107
0.65
0.49
1.7
1.8
11.69
10.42
g/l
—
7
99
7
45
1.56
0.49
1.4
1.9
—
—
—
0
0
12
85
1.42
0.47
2.1
1.3
—
—
—
0
0
12
85
1.42
0.47
1.8
1.9
—
—
—
0
0
7
48
1.47
0.47
1.9
2.0
—
—
—
0
0
7
50
1.41
0.45
2.0
1.7
—
—
—
0
0
14
104
1.36
0.43
1.2
1.3
222.08
326.10
ug/g
—
8
63
11
78
1.42
0.43
8.4
9.0
634.40
431.40
iu/ml
—
5
15
103
943
1.12
0.43
1.5
1.3
4.01
2.07
u/ml
0.28
30
258
0
15
0.00
0.41
0.0
1.4
—
205.80
—
0
15
5
35
1.43
0.39
3.8
4.1
—
—
—
0
0
5
78
0.64
0.36
1.2
2.7
1.35
0.87
nmol/l
—
5
69
380
3729
1.12
0.35
4.7
4.5
2.73
2.80
mmol/l
0.76
346
3471
20
163
1.24
0.34
2.4
1.7
—
—
—
0
0
372
3652
1.10
0.32
4.4
4.0
1.37
1.47
mmol/l
4.30
341
3409
11
142
0.77
0.31
1.2
1.4
—
—
—
0
0
119
1120
1.08
0.30
2.6
3.3
2.33
2.35
mmol/l
0.71
106
1003
21
248
0.84
0.28
1.4
1.3
—
—
—
0
0
80
861
0.91
0.28
3.2
4.1
21.97
21.13
%
0.14
35
380
8
62
1.30
0.28
2.0
2.0
—
—
—
0
0
8
62
1.30
0.28
2.0
2.0
—
—
—
0
0
9
120
0.74
0.27
1.0
1.2
—
—
—
0
0
9
120
0.74
0.27
1.0
1.2
—
—
—
0
0
8
65
1.23
0.27
4.5
3.2
52.00
56.75
%
—
8
65
9
72
1.25
0.26
1.2
1.2
—
—
—
0
0
9
75
1.20
0.25
1.8
1.5
0.43
0.38
nmol/l
—
9
62
5
38
1.32
0.23
2.2
1.8
—
—
—
0
0
27
305
0.88
0.22
1.5
1.5
—
—
—
0
0
7
95
0.73
0.22
1.7
1.7
39.89
38.10
g/l
—
7
88
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
95.00
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
104
988
1.07
0.21
1.6
1.6
1.55
1.39
mmol/l
1.20
91
846
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
8.92
—
0
14
70
657
1.08
0.20
1.2
1.3
6.79
9.89
u/ml
0.32
31
270
12
99
1.22
0.20
3.1
2.9
—
—
—
0
0
6
51
1.18
0.19
1.8
1.3
—
—
—
0
0
6
51
1.18
0.19
1.8
1.3
—
—
—
0
0
6
52
1.16
0.19
1.8
1.3
—
—
—
0
0
6
52
1.16
0.19
1.8
1.3
—
—
—
0
0
6
52
1.16
0.19
1.8
1.3
—
—
—
0
0
6
52
1.16
0.19
1.8
1.3
—
—
—
0
0
10
81
1.24
0.19
2.0
1.9
—
—
—
0
0
7
60
1.17
0.18
1.1
1.3
—
—
—
0
0
71
672
1.07
0.17
1.2
1.3
19.78
30.74
iu/ml
0.80
24
220
5
70
0.71
0.17
1.0
1.3
—
—
—
0
0
5
70
0.71
0.17
1.0
1.3
—
—
—
0
0
8
68
1.18
0.16
1.0
1.1
—
—
—
0
0
8
70
1.15
0.16
2.1
1.6
—
—
—
0
0
8
71
1.13
0.16
2.6
4.5
24.50
30.48
mg/l
—
8
45
96
922
1.05
0.14
3.0
2.7
337.00
5943.74
umol/l
3.07
82
807
10
85
1.18
0.12
2.0
1.3
—
—
—
0
0
15
166
0.90
0.10
1.4
1.4
—
—
—
0
0
15
166
0.90
0.10
1.4
1.4
—
—
—
0
0
16
176
0.91
0.09
1.4
1.5
—
—
—
0
0
61
634
0.96
0.09
2.7
2.8
0.61
0.73
ug/l
0.94
40
395
15
165
0.91
0.09
1.4
1.4
—
—
—
0
0
15
165
0.91
0.09
1.4
1.4
—
—
—
0
0
29
308
0.94
0.08
2.3
1.8
—
—
—
0
0
6
58
1.03
0.08
1.5
1.4
—
—
—
0
0
5
65
0.77
0.08
2.6
1.7
—
—
—
0
0
17
156
1.09
0.08
2.0
1.9
—
—
—
0
0
7
82
0.85
0.07
1.6
1.9
221.71
221.80
pmol/l
—
7
76
7
84
0.83
0.07
1.3
1.5
—
—
—
0
0
9
84
1.07
0.07
1.4
2.1
—
—
—
0
0
12
132
0.91
0.06
1.9
1.7
—
—
—
0
0
11
100
1.10
0.05
1.5
2.0
0.00
1.52
g/l
2.58
11
93
11
119
0.92
0.04
1.7
1.7
51.18
40.58
nmol/l
0.42
11
114
70
688
1.02
0.03
1.7
1.4
—
—
—
0
0
104
1051
0.99
0.02
4.6
4.5
1.59
2.16
ug/l
1.03
97
953
11
117
0.94
0.01
1.5
1.7
3.89
3.59
g/l
0.43
11
110
11
117
0.94
0.01
1.5
1.7
—
—
—
0
0
11
117
0.94
0.01
1.5
1.7
7.54
7.41
g/l
0.07
11
110
12
127
0.94
0.01
1.3
1.9
—
—
—
0
0
14
147
0.95
0.01
1.4
1.6
—
—
—
0
0
19
185
1.03
0.00
2.8
2.8
1.03
0.11
e6/l
0.81
19
177
22
223
0.99
0.00
1.0
1.0
—
—
—
0
0
40
397
1.01
0.00
2.2
1.8
—
—
—
0
0
29
288
1.01
0.00
1.8
2.1
13.98
13.49
nmol/l
0.08
24
265
10
99
1.01
0.00
1.0
1.2
—
—
—
0
0
10
101
0.99
0.00
1.0
1.4
—
—
—
0
0
11
109
1.01
0.00
1.5
1.8
2.39
2.99
g/l
2.00
11
102
11
111
0.99
0.00
1.4
1.4
—
—
—
0
0
5
49
1.02
0.00
3.0
2.0
14.38
13.21
%
—
5
49
9
97
0.93
0.00
1.2
1.3
—
—
—
0
0
8
85
0.94
-0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.84
—
0
5
6
61
0.98
-0.00
1.7
1.1
21.73
20.49
u/l
—
6
52
0
5
0.00
-0.00
0.0
2.0
—
11.28
—
0
5
6
63
0.95
-0.00
3.7
3.9
—
974.17
—
0
6
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXT_CELLUL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_CELLUL | 1.286 [0.98, 1.69] | 0.072 |
| Birth year | 0.997 [0.99, 1.01] | 0.431 |
During the follow-up period (1.1.1998 — 31.12.2019), 106 out of 1652 females with H8_EXT_CELLUL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_CELLUL | 1.705 [1.31, 2.22] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 161 out of 1500 males with H8_EXT_CELLUL died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXT_CELLUL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.121% | 0.288% |
| 5 | 0.819% | 1.834% |
| 10 | 1.902% | 4.388% |
| 15 | 3.84% | 7.828% |
| 20 | 6.629% | 12.988% |
Relationships between endpoints
↥Index endpoint: H8_EXT_CELLUL – Cellulitis of external ear
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data