otitis externa: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
430 |
4. Check minimum number of eventsNone |
430 |
5. Include endpointsNone |
430 |
6. Filter based on genotype QC (FinnGen only) |
430 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H60
- Name in latin
- Cellulitis auris externae
Similar endpoints
↥List of similar endpoints to
Cellulitis of external ear
based on the number of shared cases.
Similar with more cases:
- Otitis externa
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3830 | 1988 | 1820 |
| Only index persons | 3515 | 1861 | 1654 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.05 |
| Only index persons | 0.07 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 41.89 | 39.86 | 44.16 |
| Only index persons | 44.32 | 42.14 | 46.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 430 | 257 | 173 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.08 |
| Median age at first event (years) | 50.93 | 47.42 | 56.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 390
- Matched controls
- 3898
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H60.1
ICD-10 Finland
Cellulitis of external ear
+∞
323.0
390
12
H60.9
ICD-10 Finland
Otitis externa, unspecified
20.4
78.4
122
85
H60.3
ICD-10 Finland
Other infective otitis externa
43.0
55.1
68
19
H60.8
ICD-10 Finland
Other otitis externa
36.3
46.1
59
19
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
491.0
45.2
44
*
H60
ICD-10 Finland
Otitis externa
12.3
28.3
52
48
J01DB01
ATC
cefalexin; oral
4.3
21.6
354
2709
A46
ICD-10 Finland
Erysipelas
4.2
20.8
88
255
H66.0
ICD-10 Finland
Acute suppurative otitis media
4.8
19.8
71
174
H01
ICPC
Ear pain/earache
4.0
18.5
81
240
H60.0
ICD-10 Finland
Abscess of external ear
55.3
18.1
21
*
UDC00
NOMESCO Finland
Ear microscopy
5.4
17.5
54
112
H66.9
ICD-10 Finland
Otitis media, unspecified
5.2
17.3
56
122
H70
ICPC
Otitis externa
10.7
14.7
28
28
H29
ICPC
Ear symptom/complaint other
3.9
14.6
64
188
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.4
13.8
73
250
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.9
13.4
93
383
H04
ICPC
Ear discharge
8.5
13.1
28
35
J01FF01
ATC
clindamycin; systemic
2.4
11.9
129
676
H92.0
ICD-10 Finland
Otalgia
4.9
11.8
39
87
H62.0
ICD-10 Finland
Otitis externa in bacterial diseases classified elsewhere
+∞
11.5
11
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.6
10.9
85
372
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
+∞
10.5
10
*
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
24.1
10.3
14
6
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.6
9.9
78
341
H13
ICPC
Plugged feeling ear
2.6
9.8
80
356
H61.8
ICD-10 Finland
Other specified disorders of external ear
16.7
8.6
13
8
S02CA02
ATC
flumetasone and antiinfectives; otic
4.0
8.3
32
85
H65.2
ICD-10 Finland
Chronic serous otitis media
12.0
8.1
14
12
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
8.0
119
698
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
13.4
7.9
13
10
S76
ICPC
Skin infection other
3.7
7.8
33
95
H61.2
ICD-10 Finland
Impacted cerumen
4.4
7.8
27
65
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
5.4
7.7
22
43
J01MA02
ATC
ciprofloxacin; systemic
1.9
7.6
151
978
H65.3
ICD-10 Finland
Chronic mucoid otitis media
5.8
7.5
20
36
H65.0
ICD-10 Finland
Acute serous otitis media
7.9
7.5
16
21
N02AJ06
ATC
codeine and paracetamol; systemic
1.9
7.4
152
999
D07CC01
ATC
betamethasone and antibiotics; topical
2.5
7.4
61
272
D07AC01
ATC
betamethasone; topical
1.9
7.2
137
872
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.9
7.1
22
47
L03.2
ICD-10 Finland
Cellulitis of face
12.3
7.1
12
10
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
10.3
7.1
13
13
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
6.5
153
1036
H70.0
ICD-10 Finland
Acute mastoiditis
70.9
6.4
7
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.7
6.4
20
44
DC1AD
NOMESCO Finland
Temporalbone CT
11.3
6.3
11
10
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
+∞
6.3
6
*
DFF00
NOMESCO Finland
Pure tone audiometry
2.8
6.3
38
144
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
6.0
183
1336
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
256
1978
1.73
6.96
5.1
4.4
6.5
6.6
mmol/l
0.17
242
1811
25
83
3.14
6.18
1.4
1.7
—
—
—
0
0
84
504
1.83
5.39
1.9
1.8
—
—
—
0
0
397
3604
2.32
5.36
16.2
12.4
23.3
22.5
mg/l
0.17
349
2789
395
3595
2.21
5.01
16.4
13.6
139.6
139.6
mmol/l
0.04
389
3499
396
3609
2.23
4.98
16.5
13.7
4.0
4.0
mmol/l
0.03
390
3507
307
2606
1.62
4.84
4.7
3.9
11.5
10.6
mm/h
0.57
287
2415
37
177
2.19
4.47
1.6
1.4
—
—
—
0
0
187
1437
1.53
4.46
6.4
5.8
1.2
1.2
mmol/l
1.70
166
1316
249
2040
1.52
4.36
10.7
9.2
4.3
4.0
e9/l
1.20
210
1796
307
2641
1.57
4.23
7.6
7.3
73.5
76.9
u/l
0.78
291
2478
129
928
1.56
4.08
3.0
2.9
0.2
0.4
e6/l
2.82
94
691
207
1665
1.47
3.76
3.6
4.1
—
—
—
0
0
156
1189
1.49
3.71
3.7
3.3
30.5
34.1
ng/l
0.15
100
755
367
3332
1.69
3.67
14.2
11.1
90.0
86.5
ml/min/173m2
2.01
308
2718
360
3262
1.64
3.51
4.6
4.6
1.8
1.9
mu/l
0.30
330
3027
57
347
1.74
3.46
1.8
1.8
—
—
—
0
0
155
1194
1.47
3.45
2.7
3.4
29.5
32.7
u/l
0.92
149
1137
58
356
1.73
3.42
12.4
21.2
1.2
1.3
inr
0.12
11
51
56
341
1.74
3.40
1.8
1.8
—
—
—
0
0
81
550
1.58
3.24
2.6
2.7
1.2
0.8
e6/l
0.61
46
307
86
595
1.56
3.17
3.3
3.4
1371.3
310.4
ng/l
0.65
57
416
212
1751
1.42
3.16
5.4
6.3
10.5
11.0
umol/l
0.15
198
1666
168
1334
1.43
3.11
4.8
4.8
35.0
36.1
g/l
1.61
155
1250
14
50
2.86
3.11
3.6
5.5
329.6
364.8
umol/l
0.37
14
45
24
113
2.19
3.06
2.0
1.7
—
—
—
0
0
71
477
1.59
2.97
2.9
2.3
2.4
2.4
g/l
0.12
65
436
66
438
1.60
2.90
3.1
2.4
22.9
24.1
%
0.30
61
378
11
36
3.11
2.83
1.1
1.3
—
—
—
0
0
37
214
1.80
2.69
2.1
1.6
—
—
—
0
0
149
1183
1.40
2.69
3.6
3.1
—
—
—
0
0
121
929
1.42
2.64
3.6
4.1
17.0
12.7
mg/mmol
0.22
76
600
189
1569
1.37
2.57
7.6
6.6
1.2
1.2
mmol/l
1.96
160
1333
74
521
1.51
2.51
2.8
2.8
3.7
2.5
e6/l
0.42
38
280
120
928
1.41
2.50
2.0
2.1
258.8
279.8
u/l
0.05
111
877
43
270
1.66
2.37
8.3
8.4
122.8
119.2
g/l
0.61
43
257
20
376
0.51
2.33
1.4
1.6
—
—
—
0
0
48
314
1.60
2.26
8.1
8.0
1.4
1.0
mmol/l
0.36
37
243
9
30
3.04
2.16
16.0
14.3
1430.7
1565.8
nmol/l
—
9
30
34
206
1.71
2.15
3.6
3.3
1.4
1.3
mmol/l
0.07
25
151
23
124
1.90
2.11
2.4
1.9
—
—
—
0
0
21
111
1.94
2.04
2.8
5.2
2.1
1.6
%
0.77
21
100
105
823
1.36
1.99
2.2
2.3
—
—
—
0
0
288
2605
1.32
1.96
3.2
3.4
—
—
—
0
0
29
176
1.69
1.85
1.4
1.5
—
—
—
0
0
127
1036
1.32
1.83
2.5
2.6
53.1
55.6
u/l
0.48
114
959
17
87
1.99
1.82
5.3
3.4
8.0
8.5
kpa
0.44
17
79
338
3143
1.35
1.80
5.3
5.3
40.3
39.3
mmol/mol
0.97
309
2964
29
178
1.67
1.78
8.2
6.8
24.5
24.4
mmol/l
0.02
29
165
47
325
1.50
1.76
1.9
2.4
28.4
31.2
u/l
0.52
42
271
13
61
2.17
1.73
1.2
1.8
—
—
—
0
0
25
151
1.70
1.64
4.0
4.5
25.2
23.9
mmol/l
1.01
19
141
196
1718
1.26
1.57
4.0
3.3
0.0
0.0
estimate
0.00
45
348
396
3803
1.52
1.56
11.1
9.7
27.6
26.8
u/l
0.34
379
3691
16
86
1.89
1.52
1.2
1.3
—
—
—
0
0
102
828
1.30
1.51
1.9
1.6
—
—
—
0
0
6
21
2.88
1.51
1.0
1.1
—
—
—
0
0
6
21
2.88
1.51
1.2
1.9
—
—
—
0
0
52
385
1.40
1.40
4.9
4.1
31.5
31.1
%
0.07
31
262
6
23
2.63
1.37
1.0
1.0
—
—
—
0
0
9
42
2.17
1.34
1.1
1.1
—
—
—
0
0
65
505
1.34
1.31
2.2
1.8
1.5
1.5
%
0.32
59
450
195
1734
1.23
1.31
5.1
4.5
0.0
0.0
estimate
0.00
46
349
160
1396
1.23
1.28
2.3
2.2
78.1
75.4
nmol/l
0.57
144
1267
6
25
2.42
1.24
1.0
1.5
—
—
—
0
0
196
1752
1.22
1.23
4.0
3.4
0.0
0.0
estimate
0.50
44
337
97
803
1.27
1.23
3.2
3.2
853.8
1063.5
ng/l
0.36
83
692
10
49
2.07
1.23
1.1
1.3
—
—
—
0
0
291
2708
1.23
1.22
3.8
4.0
14.6
14.7
pmol/l
0.04
262
2471
37
266
1.43
1.19
2.7
2.3
69.9
72.9
ml/min/173m2
—
8
106
143
1242
1.23
1.19
1.9
1.9
94.7
94.3
pmol/l
0.03
63
657
5
20
2.52
1.15
1.0
1.5
1.8
1.9
mmol/l
—
5
20
14
80
1.78
1.14
1.3
1.3
—
—
—
0
0
19
119
1.62
1.13
1.5
1.5
—
—
—
0
0
99
831
1.25
1.12
2.3
2.1
2.8
3.0
mg/l
0.17
89
716
8
41
1.97
1.09
1.1
1.1
—
—
—
0
0
52
403
1.33
1.09
2.5
2.9
4.3
7.7
umol/l
2.09
40
338
19
121
1.60
1.07
1.7
1.6
—
—
—
0
0
7
33
2.14
1.06
1.4
2.0
—
—
—
0
0
7
35
2.02
1.00
1.1
1.1
—
—
—
0
0
48
373
1.32
0.99
5.2
6.9
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
23
2.19
0.98
1.0
1.2
—
—
—
0
0
5
23
2.19
0.98
1.2
1.2
—
—
—
0
0
5
23
2.19
0.98
4.6
2.5
—
—
—
0
0
90
760
1.23
0.97
1.5
1.8
1.0
1.1
mg/l
0.28
59
565
36
270
1.36
0.94
3.6
4.2
2.3
1.9
mmol/l
0.36
28
211
7
37
1.91
0.94
1.0
1.1
—
—
—
0
0
6
28
2.16
0.92
1.3
2.0
—
—
—
0
0
6
28
2.16
0.92
1.3
2.0
—
—
—
0
0
6
28
2.16
0.92
1.3
2.0
—
—
—
0
0
65
534
1.26
0.90
1.7
1.7
909.1
1209.0
nmol/l
2.12
41
411
76
636
1.24
0.89
2.4
2.2
—
—
—
0
0
6
30
2.01
0.87
1.2
1.1
—
—
—
0
0
12
187
0.63
0.80
5.8
2.3
27.2
33.6
u/ml
0.21
12
179
0
26
0.00
0.78
0.0
2.7
—
0.2
—
0
21
76
646
1.21
0.78
1.6
1.7
52459490.7
12116174.3
pmol/l
0.34
61
553
5
24
2.10
0.74
1.0
1.0
0.9
1.2
u/l
—
5
14
5
25
2.01
0.73
1.4
1.2
—
—
—
0
0
7
39
1.81
0.73
1.4
1.8
—
—
—
0
0
9
56
1.62
0.72
1.9
1.8
—
—
—
0
0
16
109
1.49
0.72
1.4
1.7
—
231.4
—
0
7
351
3390
1.19
0.71
17.4
13.3
40.9
40.3
%
0.86
263
2634
27
204
1.35
0.71
2.3
2.2
2468.0
2534.6
u/l
—
6
85
5
26
1.93
0.71
2.2
1.3
482.4
15649.5
e6/l
—
5
18
5
26
1.93
0.71
2.8
2.2
16.0
18.4
ug/l
—
5
26
12
77
1.57
0.69
1.8
1.8
—
—
—
0
0
9
59
1.54
0.68
1.9
1.6
—
—
—
0
0
178
1643
1.14
0.67
3.2
2.8
104.8
110.0
ug/l
0.15
162
1530
88
771
1.18
0.66
4.1
3.6
1.0
1.0
kg/l
0.29
16
114
106
943
1.16
0.66
4.7
3.5
0.0
0.0
estimate
0.25
42
339
148
1352
1.14
0.65
4.1
3.4
—
—
—
0
0
12
79
1.53
0.63
1.0
1.6
3.3
3.7
mmol/l
1.71
12
73
6
102
0.58
0.63
2.8
2.4
724.2
337.1
ug/l
—
6
96
13
88
1.49
0.61
1.1
1.6
456.8
393.9
mg/l
0.56
13
82
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.4
—
10.5
—
0
17
0
23
0.00
0.58
0.0
1.4
—
3.6
—
0
7
8
54
1.49
0.57
1.0
1.1
—
—
—
0
0
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
6
36
1.68
0.57
2.3
1.3
—
—
—
0
0
11
74
1.50
0.54
8.4
8.6
634.4
458.9
iu/ml
—
5
14
358
3485
1.16
0.53
4.3
4.1
4.5
4.7
mmol/l
1.56
324
3272
66
577
1.17
0.53
2.4
2.1
—
—
—
0
0
6
100
0.59
0.52
1.8
1.8
11.4
10.3
g/l
—
6
90
343
3334
1.14
0.50
3.9
3.7
1.4
1.3
mmol/l
3.59
311
3107
7
45
1.56
0.49
2.0
1.6
—
—
—
0
0
17
129
1.33
0.46
1.6
1.3
—
—
—
0
0
74
823
0.88
0.44
3.3
4.1
22.0
21.2
%
0.14
35
357
11
78
1.42
0.43
2.2
1.3
—
—
—
0
0
5
31
1.62
0.43
3.8
3.9
—
—
—
0
0
98
897
1.12
0.42
1.5
1.3
4.4
2.2
u/ml
0.29
27
244
346
3379
1.12
0.40
4.5
4.1
6.1
5.9
mmol/l
1.48
318
3119
12
88
1.37
0.40
3.1
3.0
—
—
—
0
0
0
18
0.00
0.40
0.0
7.5
—
34.5
—
0
6
19
236
0.80
0.39
1.4
1.3
—
—
—
0
0
16
203
0.78
0.39
1.2
1.4
—
—
—
0
0
9
66
1.37
0.38
1.2
1.2
—
—
—
0
0
5
36
1.39
0.38
2.2
1.6
—
—
—
0
0
8
112
0.71
0.37
1.0
1.2
—
—
—
0
0
8
112
0.71
0.37
1.0
1.2
—
—
—
0
0
5
78
0.64
0.36
1.2
2.5
1.4
0.8
nmol/l
—
5
69
257
2483
1.09
0.35
3.1
3.1
43.5
42.9
u/l
0.07
237
2365
6
88
0.68
0.33
1.8
1.7
40.5
38.0
g/l
—
6
77
10
74
1.36
0.32
2.0
1.9
—
—
—
0
0
6
47
1.28
0.32
1.8
1.3
—
—
—
0
0
81
749
1.10
0.30
1.6
1.5
20.5
20.4
nmol/l
0.02
68
644
36
318
1.14
0.28
3.6
2.9
—
—
—
0
0
8
63
1.27
0.28
1.0
1.1
—
—
—
0
0
8
65
1.24
0.27
2.1
1.5
—
—
—
0
0
19
161
1.19
0.24
2.5
1.7
—
—
—
0
0
11
136
0.80
0.23
1.2
1.4
—
—
—
0
0
111
1056
1.07
0.22
2.6
3.3
2.3
2.3
mmol/l
1.04
98
938
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
9.0
—
0
13
358
3534
1.08
0.20
4.7
4.5
2.7
2.8
mmol/l
0.54
324
3291
68
637
1.08
0.20
1.2
1.3
21.3
30.6
iu/ml
0.56
21
208
6
48
1.25
0.20
1.8
1.3
—
—
—
0
0
6
48
1.25
0.20
1.8
1.3
—
—
—
0
0
6
48
1.25
0.20
1.8
1.3
—
—
—
0
0
6
48
1.25
0.20
1.8
1.3
—
—
—
0
0
6
48
1.25
0.20
1.8
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
3.1
—
211.6
—
0
14
92
875
1.07
0.19
3.0
2.7
334.0
6674.0
umol/l
3.30
77
761
17
147
1.16
0.18
2.0
1.9
—
—
—
0
0
7
58
1.21
0.18
1.1
1.3
—
—
—
0
0
350
3459
1.06
0.17
4.4
4.0
1.4
1.5
mmol/l
4.73
319
3231
8
68
1.18
0.16
2.6
4.6
24.5
31.3
mg/l
—
8
43
57
606
0.93
0.16
2.8
2.7
0.6
0.7
ug/l
0.60
38
376
66
624
1.07
0.16
1.2
1.3
7.6
8.5
u/ml
0.06
27
257
8
73
1.10
0.16
1.7
1.5
0.4
0.4
nmol/l
—
8
60
9
80
1.13
0.15
2.0
1.3
—
—
—
0
0
9
82
1.10
0.15
1.4
2.1
—
—
—
0
0
97
1008
0.95
0.14
4.7
4.5
1.7
2.2
ug/l
0.74
90
917
5
47
1.06
0.09
3.8
2.6
3039.9
6.8
u/ml
—
5
42
6
55
1.09
0.09
1.5
1.4
—
—
—
0
0
6
58
1.03
0.08
3.7
3.7
—
974.2
—
0
6
5
60
0.83
0.08
2.6
1.7
—
—
—
0
0
5
64
0.78
0.08
1.0
1.4
—
—
—
0
0
5
64
0.78
0.08
1.0
1.4
—
—
—
0
0
7
80
0.87
0.07
1.6
1.9
221.7
220.8
pmol/l
—
7
74
26
275
0.94
0.07
1.8
2.1
14.9
13.5
nmol/l
0.21
21
252
8
90
0.89
0.07
1.3
1.3
—
—
—
0
0
19
177
1.08
0.06
2.8
2.8
1.0
0.1
e6/l
0.81
19
169
28
294
0.95
0.06
2.0
1.8
—
—
—
0
0
10
110
0.91
0.05
1.5
1.8
—
—
—
0
0
28
291
0.96
0.04
1.6
1.5
—
—
—
0
0
22
211
1.04
0.03
1.0
1.0
—
—
—
0
0
65
639
1.02
0.03
1.7
1.4
—
—
—
0
0
15
158
0.95
0.02
1.4
1.4
—
—
—
0
0
15
158
0.95
0.02
1.4
1.4
—
—
—
0
0
16
168
0.95
0.02
1.4
1.5
—
—
—
0
0
11
103
1.07
0.02
1.4
1.4
—
—
—
0
0
15
157
0.95
0.01
1.4
1.4
—
—
—
0
0
15
157
0.95
0.01
1.4
1.4
—
—
—
0
0
93
938
0.99
0.01
1.6
1.6
1.6
1.4
mmol/l
1.27
80
805
39
383
1.02
0.01
2.0
1.9
—
—
—
0
0
10
94
1.07
0.01
1.5
2.1
0.0
1.2
g/l
—
10
87
11
115
0.96
0.00
1.7
1.7
51.2
40.1
nmol/l
0.45
11
110
10
96
1.04
0.00
1.0
1.4
—
—
—
0
0
12
124
0.97
0.00
1.3
2.0
—
—
—
0
0
12
123
0.97
0.00
1.9
1.7
—
—
—
0
0
14
137
1.02
0.00
1.4
1.6
—
—
—
0
0
9
90
1.00
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
11.3
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
6.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
82
0.98
0.00
1.1
1.2
—
—
—
0
0
12
120
1.00
0.00
1.5
2.8
99.0
90.4
%
0.82
12
113
6
59
1.02
0.00
1.7
1.1
21.7
14.6
u/l
—
6
50
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
98.0
—
0
6
0
6
0.00
0.00
0.0
4.5
—
—
—
0
0
7
79
0.88
0.00
1.3
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXT_CELLUL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_CELLUL | 1.286 [0.98, 1.69] | 0.072 |
| Birth year | 0.997 [0.99, 1.01] | 0.431 |
During the follow-up period (1.1.1998 — 31.12.2019), 106 out of 1652 females with H8_EXT_CELLUL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXT_CELLUL | 1.705 [1.31, 2.22] | < 0.001 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 161 out of 1500 males with H8_EXT_CELLUL died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXT_CELLUL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.121% | 0.288% |
| 5 | 0.819% | 1.834% |
| 10 | 1.902% | 4.388% |
| 15 | 3.84% | 7.828% |
| 20 | 6.629% | 12.988% |
Relationships between endpoints
↥Index endpoint: H8_EXT_CELLUL – Cellulitis of external ear
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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