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Explicit fungal Sepsis

AB1_SEPSIS_FUNGAL_EXPL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B37.7
  • Hospital discharge: ICD-9 1125A
  • Cause of death: ICD-10 B37.7
  • Cause of death: ICD-9 1125A

2 out of 7 registries used, show all original rules.

220

4. Check minimum number of events

None

220

5. Include endpoints

None

220

6. Filter based on genotype QC (FinnGen only)

220

Control definitions (FinnGen only)

Control exclude
AB1_SEPSIS_EXPLICIT, AB1_SEPSIS_IMPLICIT

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 220 80 140
Unadjusted period prevalence (%) 0.05 0.03 0.06
Median age at first event (years) 64.89 61.22 66.99

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
192
Matched controls
1919
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B37.7
ICD-10 Finland
Candidal sepsis
+∞
266.1
188
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
17.7
59.3
105
122
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
32.1
57.2
77
39
A41.9
ICD-10 Finland
Sepsis, unspecified
+∞
56.0
51
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
15.8
43.4
76
76
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
480.5
40.7
39
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
227.6
37.2
37
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
10.5
36.7
81
125
A41.8
ICD-10 Finland
Other specified sepsis
+∞
36.6
34
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
35.1
35.8
46
17
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
10.4
34.7
76
114
J18.9
ICD-10 Finland
Pneumonia, unspecified
7.3
32.0
96
232
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
10.3
31.5
68
97
TPH07
NOMESCO Finland
Cathetrisation of artery
11.2
29.7
60
75
N17.9
ICD-10 Finland
Acute renal failure, unspecified
58.6
29.5
34
7
N02AA05
ATC
oxycodone; systemic
8.5
29.2
72
127
R50.9
ICD-10 Finland
Fever, unspecified
8.4
27.4
67
115
WX872
NOMESCO Finland
Intensive care
18.3
26.2
41
28
J01MA12
ATC
levofloxacin; systemic
6.5
25.9
80
190
JN4BD
NOMESCO Finland
Extensive body CT
7.6
25.0
65
121
TPX10
NOMESCO Finland
Implantation of vascular injection port
27.2
24.9
34
15
AA1AD
NOMESCO Finland
CT of head and brain
5.9
24.9
85
227
WX408
NOMESCO Finland
General anesthesy, balanced
5.6
24.9
93
277
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
10.8
24.3
49
59
JN3AD
NOMESCO Finland
Abdominal CT examination
10.4
23.9
49
61
JN3BD
NOMESCO Finland
Extensive abdominal CT
8.9
23.7
54
81
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
8.5
23.1
54
84
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.7
22.4
126
557
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
22.3
21
*
C03CA01
ATC
furosemide; systemic
4.8
21.2
92
310
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
18.0
20.6
32
21
JN4AD
NOMESCO Finland
Body CT examination
9.0
20.3
45
63
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.6
20.2
91
315
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
82.1
20.1
22
*
TK800
NOMESCO Finland
Hemodialysis
45.3
20.0
24
6
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
10.5
19.9
40
47
WX892
NOMESCO Finland
Monitored bed care
9.5
19.7
42
55
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
+∞
19.1
18
*
TPH04
NOMESCO Finland
Cathetrisation of vein
4.8
18.2
72
214
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
197.5
17.8
18
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
6.5
17.2
48
94
JAH00
NOMESCO Finland
Laparotomy
18.6
17.1
26
16
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
5.1
17.1
61
161
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
20.9
16.5
24
13
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
8.8
16.4
36
49
WX302
NOMESCO Finland
Thoracal epidural anesthesy
9.3
15.6
33
42
WW500
NOMESCO Finland
Blood transfusion
11.6
15.6
29
29
N03AX16
ATC
pregabalin; oral
4.2
15.5
71
237
J01MA02
ATC
ciprofloxacin; systemic
3.6
15.4
102
462
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
6.3
15.3
43
84
N18.8
ICD-10 Finland
Other chronic renal failure
20.5
15.1
22
12
J02AC01
ATC
fluconazole; systemic
3.6
14.9
94
408
R11
ICD-10 Finland
Nausea and vomiting
7.7
14.7
35
54
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
39.4
14.7
18
5
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.0
14.1
67
229
WX002
NOMESCO Finland
Sedation and analgesia
4.1
14.0
63
204
A06AD11
ATC
lactulose; oral
4.8
13.7
49
127
J01MA14
ATC
moxifloxacin; systemic
5.7
13.6
41
87
L89
ICD-10 Finland
Decubitus ulcer and pressure area
43.4
13.4
16
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
7.7
13.2
31
47
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.0
13.2
33
55
A03FA01
ATC
metoclopramide; systemic, rectal
3.8
13.1
65
228
SPAT1255
SPAT
Intravenous administration of medicine
7.9
13.0
30
44
D64.9
ICD-10 Finland
Anaemia, unspecified
5.1
13.0
43
102
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
8.7
13.0
28
37
WX882
NOMESCO Finland
High dependency care
11.3
12.9
24
24
JFB00
NOMESCO Finland
Partial resection of small intestine
34.7
12.8
16
5
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
12.9
12.7
22
19
A10AE04
ATC
insulin glargine; parenteral
6.0
12.7
36
71
GD1AD
NOMESCO Finland
Thorax CT examination
10.8
12.7
24
25
SPAT1262
SPAT
Handing over of treatment supplies
3.9
12.5
59
197
TQW11
NOMESCO Finland
Vacuum treatment of wound
19.7
12.3
18
10
UKC02
NOMESCO Finland
Cystoscopy
3.8
12.3
59
200
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
10.7
12.1
23
24
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
6.3
11.9
32
59
I50.9
ICD-10 Finland
Heart failure, unspecified
4.7
11.7
42
108
J96.0
ICD-10 Finland
Acute respiratory failure
+∞
11.6
11
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.7
11.6
58
203
WX730
NOMESCO Finland
Conventional respirator
37.5
11.4
14
*
GBB00
NOMESCO Finland
Tracheostomy
37.5
11.4
14
*
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
18.5
11.4
17
10
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
9.5
11.4
23
27
J01FF01
ATC
clindamycin; systemic
3.3
11.4
70
285
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.0
11.2
25
35
R31
ICD-10 Finland
Unspecified haematuria
4.5
11.2
42
113
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.0
11.1
82
379
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
8.9
11.0
23
29
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
12.3
10.8
19
17
A02BC02
ATC
pantoprazole; systemic
2.9
10.7
133
845
R33
ICD-10 Finland
Retention of urine
5.2
10.5
33
73
KA3EB
NOMESCO Finland
Antegrade pyelography
116.1
10.5
11
*
N17.8
ICD-10 Finland
Other acute renal failure
116.1
10.5
11
*
X59
ICD-10 Finland
Exposure to unspecified factor
3.6
10.5
53
185
N30.0
ICD-10 Finland
Acute cystitis
4.4
10.5
40
109
JDB10
NOMESCO Finland
Percutaneous gastrostomy
20.2
10.4
15
8
N02AX02
ATC
tramadol; systemic, rectal
2.8
10.4
100
540
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
25.0
10.4
14
6
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
6.1
10.3
28
52
C07AB07
ATC
bisoprolol; oral
2.7
10.3
112
648
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
5.3
10.1
31
67
J04AB02
ATC
rifampicin; systemic
42.5
10.1
12
*
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
11.6
10.0
18
17
B99
ICD-10 Finland
Other and unspecified infectious diseases
21.4
10.0
14
7
B03XA02
ATC
darbepoetin alfa; parenteral
27.7
9.9
13
5
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.2
9.8
31
69
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
4.6
9.8
35
89
B01AB10
ATC
tinzaparin; parenteral
6.2
9.8
26
47
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
12.3
9.8
17
15
B01AB05
ATC
enoxaparin; parenteral
2.9
9.8
75
349
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
58.0
9.8
11
*
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
16.1
9.7
15
10
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.0
9.7
65
277
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
7.1
9.6
23
36
XW000
NOMESCO Finland
Bone marrow biopsy
7.1
9.6
23
36
E87.5
ICD-10 Finland
Hyperkalaemia
18.7
9.6
14
8
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
13.3
9.6
16
13
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
13.3
9.6
16
13
ZZA00
NOMESCO Finland
Split skin graft
13.3
9.6
16
13
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.3
9.5
36
97
TPX15
NOMESCO Finland
Removal of vascular injection port
105.0
9.5
10
*
JAH33
NOMESCO Finland
Opening of laparostomy
105.0
9.5
10
*
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
105.0
9.5
10
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
23.1
9.5
13
6
A40.8
ICD-10 Finland
Other streptococcal sepsis
+∞
9.4
9
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.2
9.4
29
63
103
Kela drug reimbursment
Diabetes, insulin-treated
2.9
9.3
70
317
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.9
9.3
40
122
R53
ICD-10 Finland
Malaise and fatigue
3.4
9.2
47
165
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
6.6
9.1
23
39
E86
ICD-10 Finland
Volume depletion
13.4
9.0
15
12
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
9.0
49
179
ZX120
NOMESCO Finland
Intravenous
4.5
9.0
32
81
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
7.2
9.0
21
32
WX704
NOMESCO Finland
Intubation
6.4
8.9
23
40
S97
ICPC
Chronic ulcer skin
7.6
8.8
20
29
J01XX08
ATC
linezolid; systemic
52.4
8.8
10
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
52.4
8.8
10
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
7.3
8.6
20
30
A07AA02
ATC
nystatin; oral
6.1
8.6
23
42
V03AE01
ATC
polystyrene sulfonate; oral
29.0
8.6
11
*
JFF13
NOMESCO Finland
Terminal enterostomy
94.0
8.5
9
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
94.0
8.5
9
*
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
94.0
8.5
9
*
A11CC03
ATC
alfacalcidol; systemic
11.5
8.5
15
14
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.2
8.4
22
39
UJD02
NOMESCO Finland
Gastroscopy
6.2
8.4
22
39
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
+∞
8.4
8
*
A04AA01
ATC
ondansetron; systemic, rectal
5.6
8.4
24
48
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
8.4
53
215
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
8.3
77
390
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
15.4
8.3
13
9
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
15.4
8.3
13
9
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
8.8
8.3
17
21
E87.6
ICD-10 Finland
Hypokalaemia
12.5
8.2
14
12
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
18.2
8.2
12
7
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.6
8.1
28
69
K65.0
ICD-10 Finland
Acute peritonitis
23.2
8.1
11
5
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
23.2
8.1
11
5
SPAT1254
SPAT
Administration of medicine
3.5
8.1
39
130
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
8.4
8.1
17
22
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
13.8
8.0
13
10
WX725
NOMESCO Finland
Noninvasive ventilation
7.5
8.0
18
26
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
5.2
8.0
24
51
EBA15
NOMESCO Finland
Extraction of large number of teeth
6.4
7.9
20
34
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
11.5
7.9
14
13
N05BA04
ATC
oxazepam; oral
2.7
7.9
61
280
A28
ICPC
Limited function/disability NOS
3.5
7.9
37
121
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
15.9
7.8
12
8
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
4.9
7.8
25
57
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
46.9
7.8
9
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
6.3
7.8
20
35
A46
ICD-10 Finland
Erysipelas
3.4
7.7
39
135
KA1AE
NOMESCO Finland
Kidney ultrasound examination
10.7
7.7
14
14
N05AH03
ATC
olanzapine; systemic
6.1
7.6
20
36
A10AE05
ATC
insulin detemir; parenteral
6.1
7.6
20
36
R55
ICD-10 Finland
Syncope and collapse
5.4
7.6
22
45
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
8.2
7.6
16
21
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
4.1
7.5
29
80
127
Kela drug reimbursment
Transplant complication
14.1
7.5
12
9
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
14.1
7.5
12
9
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
14.1
7.5
12
9
R4190
NOMESCO Finland
Nutritional therapy
7.3
7.5
17
25
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
83.2
7.5
8
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.3
7.5
27
70
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
10.0
7.4
14
15
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.4
7.3
26
66
JFA70
NOMESCO Finland
Suture of small intestine
+∞
7.3
7
*
TK810
NOMESCO Finland
Hemofiltration
+∞
7.3
7
*
NHQ40
NOMESCO Finland
Amputation of toe
16.6
7.3
11
7
A04AA02
ATC
granisetron; systemic, transdermal
5.2
7.3
22
47
N05AA02
ATC
levomepromazine; systemic
7.1
7.3
17
26
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
6.1
7.3
19
34
T36
ICD-10 Finland
Poisoning by systemic antibiotics
8.5
7.3
15
19
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
8.5
7.3
15
19
B18.2
ICD-10 Finland
Chronic viral hepatitis C
31.3
7.2
9
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
31.3
7.2
9
*
L28
ICPC
Limited function/disability (L)
3.2
7.2
39
140
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
14.5
7.0
11
8
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
6.1
7.0
18
32
P01AB01
ATC
metronidazole; oral, rectal
2.3
6.9
80
449
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.6
6.8
57
269
KBV00
NOMESCO Finland
Insertion of stent into ureter
41.6
6.8
8
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.7
6.8
22
51
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.9
6.8
18
33
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
23.5
6.7
9
*
A07AA09
ATC
vancomycin; oral
23.5
6.7
9
*
Z93.3
ICD-10 Finland
Colostomy status
23.5
6.7
9
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
5.6
6.5
18
35
UKB02
NOMESCO Finland
Retrograde ureteroscopy
72.1
6.5
7
*
TJD20
NOMESCO Finland
Change of gastrostomy tube
72.1
6.5
7
*
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
72.1
6.5
7
*
Z72.2
ICD-10 Finland
Drug use
72.1
6.5
7
*
WW200
NOMESCO Finland
Immunization
8.6
6.4
13
16
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
9.8
6.4
12
13
K92.1
ICD-10 Finland
Melaena
4.8
6.4
20
45
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.0
6.4
39
152
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
11.6
6.4
11
10
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
18.8
6.3
9
5
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
18.8
6.3
9
5
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.0
6.3
19
41
Z93.2
ICD-10 Finland
Ileostomy status
+∞
6.3
6
*
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
+∞
6.3
6
*
KBV15
NOMESCO Finland
Cystoscopic change of ureteral stent
+∞
6.3
6
*
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
+∞
6.3
6
*
XX4AT
NOMESCO Finland
Other canalization with ultrasound guidance
+∞
6.3
6
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.0
6.3
24
66
TKC20
NOMESCO Finland
Catheterisation of bladder
4.1
6.3
23
61
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
5.5
6.2
17
33
SPAT1167
SPAT
Insertion of urinary catheter
7.1
6.2
14
21
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
13.1
6.2
10
8
L04AA06
ATC
mycophenolic acid; systemic
13.1
6.2
10
8
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
13.1
6.2
10
8
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
13.1
6.2
10
8
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
9.1
6.2
12
14
K29.7
ICD-10 Finland
Gastritis, unspecified
9.1
6.2
12
14
B01AA03
ATC
warfarin; systemic
2.6
6.1
51
237
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.8
6.1
41
169
UDQ12
NOMESCO Finland
Flexible laryngoscopy
5.1
6.1
18
38
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.4
6.1
29
96
N05CD07
ATC
temazepam; oral
3.0
6.0
35
133
F29
ICD-10 Finland
Unspecified nonorganic psychosis
7.7
6.0
13
18

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
103
120
15.26
89.15
20.9
5.3
11.7
8.7
mmol/l
2.61
98
113
117
194
11.75
76.83
17.6
4.7
1.1
1.0
mmol/l
2.20
112
178
155
440
9.54
60.35
29.1
3.5
—
—
—
0
0
58
52
14.79
57.77
3.4
1.7
1.6
0.3
ug/l
1.77
53
45
109
245
7.84
51.92
5.9
1.7
—
—
—
0
0
61
76
10.72
48.20
1.8
1.9
1.7
1.4
g/l
0.83
55
63
92
188
7.69
47.55
3.7
1.5
—
—
—
0
0
77
142
7.80
43.49
20.3
3.2
2.0
1.7
mmol/l
0.23
66
111
73
143
7.14
38.54
4.3
2.3
67.8
67.5
e9/l
0.03
57
116
68
124
7.49
38.45
39.7
5.5
—
—
—
0
0
82
202
5.88
33.69
4.1
2.6
1.9
1.7
%
0.46
72
180
137
555
4.89
29.96
19.2
5.0
—
—
—
0
0
72
177
5.56
29.24
30.5
4.9
1.0
1.2
mmol/l
0.12
63
136
81
221
5.22
29.13
6.2
2.1
18.8
23.0
%
1.41
69
192
120
448
4.69
28.99
8.0
2.8
—
—
—
0
0
115
424
4.59
28.05
4.3
1.9
3.7
3.1
mg/l
1.07
104
364
88
264
4.89
28.05
5.8
2.1
8.9
13.2
umol/l
5.41
80
244
130
533
4.52
27.30
6.4
2.3
63.5
56.2
u/l
0.47
119
492
81
236
4.85
26.61
6.1
2.1
2.0
2.3
g/l
4.91
75
220
51
107
5.90
24.35
10.1
2.8
7.4
7.4
ph
—
9
8
152
739
4.42
24.31
26.0
4.2
29.6
35.9
g/l
21.47
145
696
160
823
4.46
23.25
34.1
5.5
1.2
1.2
mmol/l
2.19
137
697
52
116
5.56
23.16
2.1
2.2
59.6
67.1
g/l
4.43
46
107
144
691
4.14
23.05
26.8
8.4
1.3
1.3
inr
0.04
37
219
42
80
6.25
22.07
36.0
5.7
—
—
—
0
0
150
756
4.09
21.99
33.9
4.6
1.2
1.2
mmol/l
1.93
141
681
167
914
4.43
21.54
25.4
5.5
11.9
11.3
umol/l
0.23
160
866
25
27
10.32
21.28
15.5
1.9
—
—
—
0
0
117
520
3.67
20.30
10.5
2.2
—
—
—
0
0
77
263
3.97
19.76
2.7
1.8
—
—
—
0
0
44
97
5.42
19.70
18.3
3.7
—
—
—
0
0
63
190
4.25
19.16
12.2
2.6
6.7
8.3
umol/l
0.48
52
167
24
29
9.17
18.75
1.6
1.4
—
—
—
0
0
86
328
3.66
18.60
6.5
2.4
480.3
583.3
mosm/kgh2o
5.16
79
274
145
772
3.58
18.30
15.5
3.8
—
—
—
0
0
95
392
3.51
18.09
10.1
2.2
—
—
—
0
0
51
137
4.54
17.96
3.8
1.9
9.8
10.6
g/l
0.36
46
123
64
204
4.01
17.94
2.9
1.3
—
—
—
0
0
110
502
3.38
17.72
3.9
2.0
193.4
256.6
u/l
0.40
104
471
40
91
5.15
17.18
1.5
2.0
—
—
—
0
0
60
190
3.97
16.88
2.5
1.4
—
—
—
0
0
27
45
6.70
16.00
1.7
2.9
90.8
170.1
mg/l
0.26
22
38
27
45
6.70
16.00
1.6
2.9
57.1
27.5
mg/l
2.02
22
38
108
516
3.15
15.64
15.1
3.5
7.4
7.4
ph
0.22
26
95
22
30
8.04
15.54
12.1
2.5
—
—
—
0
0
148
851
3.26
15.41
20.5
5.4
0.7
0.6
e9/l
5.29
141
736
148
853
3.25
15.30
20.6
5.5
0.0
0.0
e9/l
0.37
141
743
63
220
3.61
15.23
2.6
1.5
—
—
—
0
0
127
677
3.07
14.97
6.9
2.4
401.9
129.3
ug/l
1.93
118
616
149
873
3.19
14.76
20.8
5.5
2.1
1.9
e9/l
0.18
144
775
78
318
3.25
14.67
2.1
1.7
1182.1
1169.3
nmol/l
0.04
59
243
21
29
7.90
14.66
1.3
1.1
—
—
—
0
0
149
877
3.17
14.56
22.0
5.6
0.2
0.2
e9/l
0.64
142
778
34
80
4.84
13.94
13.1
2.7
1.6
1.2
%
0.72
34
80
16
17
10.07
13.60
2.9
1.9
91.8
90.1
%
0.66
16
17
22
35
6.87
13.56
3.9
1.4
—
—
—
0
0
45
135
3.93
13.47
3.4
2.3
7.6
7.4
ug/l
0.02
39
118
17
20
9.13
13.43
2.1
1.4
—
—
—
0
0
17
20
9.13
13.43
2.1
1.4
—
—
—
0
0
17
20
9.13
13.43
2.1
1.4
—
—
—
0
0
17
20
9.13
13.43
2.1
1.4
—
—
—
0
0
25
47
5.87
13.10
1.4
1.4
—
—
—
0
0
40
115
4.03
12.66
2.0
1.5
—
—
—
0
0
23
42
6.00
12.40
14.0
2.9
—
—
—
0
0
95
468
2.81
12.38
9.5
3.1
0.9
0.3
e6/l
0.54
86
334
20
32
6.78
12.23
1.5
3.5
—
—
—
0
0
102
524
2.76
12.22
9.9
3.0
80.1
166.5
e6/l
0.30
94
392
157
1005
2.96
12.22
33.9
8.8
5.2
4.0
e9/l
5.59
151
885
13
12
11.45
12.07
1.3
1.5
—
—
—
0
0
18
26
7.45
12.04
5.3
2.4
15.3
15.7
%
—
8
11
72
312
2.94
11.85
7.2
3.1
115.5
287.2
ng/l
0.99
64
251
16
21
8.14
11.57
2.1
1.4
—
—
—
0
0
33
88
4.24
11.52
11.0
2.8
—
—
—
0
0
15
6
26.65
11.30
8.1
2.0
29.3
29.2
umol/l
—
15
6
16
22
7.76
11.14
1.4
1.1
—
—
—
0
0
14
17
8.73
10.73
1.6
2.3
1.4
1.0
e9/l
—
8
5
41
134
3.53
10.72
6.1
4.5
0.3
0.3
%
0.03
17
32
81
396
2.65
10.39
2.4
1.5
20.6
19.8
nmol/l
0.22
74
328
13
15
9.15
10.33
2.6
2.7
—
—
—
0
0
54
214
3.02
10.28
19.0
20.1
1.4
1.3
inr
—
8
31
90
467
2.57
10.18
9.5
2.9
—
—
—
0
0
12
13
9.71
9.96
16.3
2.5
—
—
—
0
0
16
25
6.82
9.95
4.3
2.5
—
—
—
0
0
100
550
2.50
9.94
5.3
3.3
6.3
8.0
mmol/l
3.09
83
455
43
152
3.27
9.91
6.9
4.4
0.6
0.7
%
0.05
21
46
105
600
2.43
9.49
11.9
3.5
891.4
119.3
e6/l
0.79
94
420
41
147
3.20
9.20
2.4
1.3
—
—
—
0
0
14
21
7.05
9.00
2.6
4.8
—
—
—
0
0
115
698
2.36
8.91
3.0
1.9
94.5
91.5
pmol/l
0.27
77
362
24
62
4.22
8.68
16.9
4.9
1.7
1.5
%
0.37
24
56
17
33
5.50
8.55
1.4
1.4
—
—
—
0
0
81
432
2.38
8.33
6.1
2.7
382.4
7310.1
umol/l
1.92
73
360
68
341
2.44
7.97
1.7
1.8
519.6
421.1
pmol/l
1.09
54
288
13
21
6.52
7.80
1.4
1.3
—
—
—
0
0
11
6
19.20
7.68
4.2
2.2
—
—
—
0
0
92
538
2.22
7.46
5.7
3.8
22.5
6.7
mg/mmol
2.20
71
358
46
198
2.67
7.36
1.6
1.3
128.0
634.9
titre
—
5
39
14
26
5.68
7.35
6.1
2.4
55.0
58.6
%
0.27
14
26
15
30
5.29
7.29
4.0
3.8
—
—
—
0
0
22
62
3.83
7.07
23.2
4.1
—
—
—
0
0
24
72
3.62
7.06
4.3
2.8
—
—
—
0
0
94
565
2.16
7.02
9.4
3.1
2.3
2.3
mmol/l
1.70
84
487
12
20
6.29
6.98
1.5
2.1
633.2
457.1
e6/l
—
5
8
11
8
14.38
6.97
17.2
2.6
—
—
—
0
0
105
666
2.10
6.75
7.8
3.5
106.4
46.6
ng/l
0.40
93
468
174
1345
2.40
6.65
36.3
7.0
112.7
80.6
u/l
7.51
169
1256
21
60
3.76
6.62
19.3
5.0
0.9
0.9
%
0.20
21
55
14
29
5.09
6.55
6.3
2.0
—
—
—
0
0
86
511
2.12
6.52
4.5
3.1
130.3
51.0
mg/l
1.47
69
341
10
7
14.88
6.46
1.3
1.0
—
—
—
0
0
35
140
2.78
6.41
6.7
4.7
0.1
0.1
%
0.25
21
39
13
26
5.25
6.31
4.2
2.3
4.9
4.4
e9/l
0.22
13
26
14
30
4.92
6.30
1.5
1.2
—
—
—
0
0
45
208
2.46
6.17
1.4
1.3
—
—
—
0
0
10
16
6.50
6.01
1.2
1.1
—
—
—
0
0
75
440
2.07
5.76
26.9
6.0
—
—
—
0
0
38
168
2.53
5.71
9.6
3.4
—
—
—
0
0
153
1156
2.06
5.70
11.2
3.8
—
—
—
0
0
29
614
0.39
5.45
3.2
2.9
—
—
—
0
0
14
34
4.33
5.44
13.0
4.2
—
—
—
0
0
10
18
5.77
5.37
2.2
1.6
—
—
—
0
0
9
8
11.66
5.34
2.4
1.6
2720.4
1040.9
u/ml
—
9
8
17
49
3.68
5.29
1.5
1.4
171.6
301.7
ug/g
2.34
12
31
9
9
10.36
5.07
1.3
1.1
—
—
—
0
0
31
133
2.55
4.94
7.2
4.8
0.1
0.2
%
0.39
18
37
58
328
2.04
4.82
2.1
1.4
2.4
2.6
g/l
0.29
47
199
12
29
4.32
4.69
6.7
3.3
—
—
—
0
0
9
11
8.47
4.60
5.8
1.4
10.2
11.5
%
—
9
11
9
12
7.76
4.40
1.0
1.2
—
—
—
0
0
72
453
1.88
4.34
1.5
1.3
—
—
—
0
0
45
240
2.10
4.34
1.6
1.2
—
—
—
0
0
8
9
9.17
4.31
1.9
1.6
0.3
0.1
e9/l
—
8
9
7
6
11.99
4.30
2.0
1.7
—
—
—
0
0
94
645
1.80
4.27
7.5
3.3
—
—
—
0
0
9
13
7.16
4.20
2.6
1.5
—
—
—
0
0
113
824
1.76
4.14
7.8
3.4
0.0
0.0
estimate
0.00
27
158
9
14
6.65
4.02
1.4
1.1
—
—
—
0
0
114
839
1.74
4.00
8.1
3.5
0.0
0.0
estimate
0.00
23
150
14
43
3.41
3.98
1.6
1.2
—
—
—
0
0
62
383
1.86
3.91
10.2
5.2
—
—
—
0
0
6
5
12.28
3.78
1.8
1.8
—
—
—
0
0
111
824
1.70
3.67
10.4
4.7
0.0
0.0
estimate
0.00
29
158
19
74
2.72
3.66
4.5
3.5
51.3
478.2
u/ml
0.55
14
63
6
6
10.23
3.52
1.5
1.0
153.0
158.0
nmol/l
—
6
6
59
371
1.81
3.48
7.7
3.7
—
—
—
0
0
13
42
3.23
3.43
11.2
2.7
—
—
—
0
0
7
10
7.19
3.39
2.3
1.2
—
—
—
0
0
6
7
8.77
3.28
1.5
1.1
150.0
103.8
iu/ml
—
6
7
6
7
8.77
3.28
3.2
2.4
—
—
—
0
0
9
19
4.89
3.27
5.4
1.8
29.7
32.8
pg
—
9
19
11
33
3.46
3.24
1.1
1.4
—
—
—
0
0
27
132
2.19
3.23
7.8
3.7
—
—
—
0
0
104
778
1.64
3.21
39.2
8.8
0.0
0.0
e9/l
0.78
92
645
22
100
2.33
3.11
2.0
1.2
—
—
—
0
0
7
12
5.98
3.04
1.1
1.2
—
—
—
0
0
28
143
2.10
3.01
7.8
3.1
—
—
—
0
0
8
17
4.84
2.94
1.4
1.2
—
—
—
0
0
7
13
5.52
2.89
1.1
1.2
—
—
—
0
0
7
13
5.52
2.89
1.1
1.1
—
—
—
0
0
140
1149
1.60
2.81
10.8
2.9
100.6
47.9
u/l
3.92
132
1071
74
526
1.61
2.72
6.0
3.6
—
—
—
0
0
152
1280
1.61
2.66
7.9
4.0
30.2
11.7
mm/h
11.39
143
1171
5
7
7.27
2.56
1.4
1.0
—
—
—
0
0
7
16
4.48
2.49
2.7
1.9
—
—
—
0
0
0
67
0.00
2.43
0.0
1.5
—
—
—
0
0
6
12
5.11
2.42
1.7
1.2
—
—
—
0
0
13
52
2.59
2.40
13.4
2.4
—
—
—
0
0
151
1704
0.64
2.38
5.9
4.6
3.9
4.6
mmol/l
10.84
136
1568
7
18
3.98
2.27
1.9
1.4
—
—
nmol/l
—
0
0
6
14
4.37
2.16
1.5
1.1
—
—
—
0
0
151
1693
0.66
2.13
5.7
4.5
1.2
1.4
mmol/l
7.21
133
1541
151
1691
0.66
2.09
6.2
4.7
6.7
6.0
mmol/l
3.24
135
1537
13
56
2.40
2.09
14.5
2.3
—
—
—
0
0
13
56
2.40
2.09
13.8
2.3
—
—
—
0
0
7
20
3.58
2.07
2.1
1.2
—
—
—
0
0
157
1742
0.66
2.04
5.7
5.1
2.2
2.7
mmol/l
12.41
138
1589
13
57
2.36
2.02
14.5
2.3
—
—
—
0
0
6
159
0.36
1.97
1.0
1.5
—
—
—
0
0
46
316
1.58
1.90
7.9
3.2
2.5
2.4
mmol/l
3.88
40
276
180
1933
0.62
1.86
121.3
18.9
8.5
6.6
e9/l
4.87
175
1882
180
1932
0.62
1.83
121.2
18.8
3.9
4.5
e12/l
25.57
174
1880
180
1932
0.62
1.83
120.8
18.8
90.8
91.0
fl
0.15
175
1903
180
1932
0.62
1.83
120.7
18.7
29.7
30.4
pg
3.74
175
1903
7
23
3.11
1.81
1.4
1.3
—
—
—
0
0
180
1930
0.63
1.78
121.4
18.8
251.1
242.0
e9/l
0.68
175
1881
6
18
3.40
1.76
1.7
1.4
—
—
—
0
0
13
61
2.20
1.75
3.1
1.8
—
—
—
0
0
7
25
2.86
1.66
2.7
1.8
—
—
—
0
0
38
259
1.56
1.63
1.3
1.3
38.0
39.5
iu/ml
—
8
86
16
85
1.95
1.59
1.9
2.3
—
—
—
0
0
7
26
2.75
1.59
2.7
2.2
105.0
106.6
mmol/l
—
7
26
7
26
2.75
1.59
2.7
2.2
—
—
—
0
0
7
26
2.75
1.59
2.7
2.2
4.2
4.1
mmol/l
—
7
26
6
20
3.05
1.59
1.2
1.0
—
—
—
0
0
12
57
2.17
1.58
1.3
1.5
—
—
—
0
0
60
454
1.44
1.56
9.3
3.7
0.0
0.0
estimate
0.00
23
153
5
15
3.38
1.53
5.8
7.5
1204.2
776.8
nmol/l
—
5
15
5
15
3.38
1.53
1.4
1.1
—
—
—
0
0
5
15
3.38
1.53
16.6
10.5
2276.0
1345.7
nmol/l
—
5
15
51
378
1.45
1.48
9.1
3.8
1.0
1.0
kg/l
—
6
58
18
103
1.81
1.46
4.0
2.8
3.2
3.7
e9/l
—
10
75
15
81
1.91
1.44
6.7
3.0
—
—
—
0
0
30
201
1.57
1.39
1.4
1.3
—
—
—
0
0
33
463
0.66
1.37
3.2
3.0
0.8
0.8
ug/l
0.07
28
295
10
47
2.18
1.36
5.7
3.4
—
—
—
0
0
6
24
2.54
1.31
3.2
1.4
—
—
—
0
0
5
18
2.82
1.29
1.0
1.2
—
—
—
0
0
8
36
2.27
1.25
6.1
2.1
120.1
127.9
g/l
—
8
25
11
56
2.02
1.24
16.6
1.7
—
—
—
0
0
10
49
2.09
1.24
2.2
1.2
—
—
—
0
0
5
19
2.67
1.22
1.2
1.1
—
—
—
0
0
5
20
2.53
1.15
3.6
3.3
27.4
15.0
u/ml
—
5
20
137
1228
1.31
1.11
6.7
3.8
—
—
—
0
0
153
1649
0.76
1.03
6.7
4.0
1.6
1.3
mmol/l
2.38
137
1487
46
361
1.35
0.97
1.2
1.2
1.7
0.8
u/ml
—
8
91
33
245
1.41
0.96
1.3
1.3
2.9
15.4
u/ml
—
7
107
58
474
1.30
0.93
6.9
3.0
—
—
—
0
0
80
682
1.27
0.92
3.5
2.0
—
—
—
0
0
8
42
1.94
0.89
1.1
1.4
—
383.7
—
0
22
176
1850
0.76
0.85
99.8
15.0
110.6
79.1
umol/l
4.54
176
1850
6
31
1.96
0.85
7.2
2.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.5
—
—
—
0
0
17
116
1.50
0.77
7.1
2.8
—
—
—
0
0
17
116
1.50
0.77
1.9
1.7
—
—
—
0
0
5
24
2.11
0.75
3.4
1.3
—
—
—
0
0
71
807
0.82
0.66
5.1
4.8
2.3
2.4
ug/l
0.05
63
711
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
55
473
1.22
0.58
2.9
1.6
1.9
1.4
mmol/l
2.04
50
404
6
39
1.55
0.53
1.8
1.2
—
—
—
0
0
19
144
1.35
0.52
1.3
1.5
—
—
—
0
0
130
1220
1.16
0.48
4.9
3.7
14.8
14.8
pmol/l
0.06
118
1087
154
1612
0.85
0.47
9.4
5.9
45.5
40.3
mmol/mol
3.62
144
1484
11
77
1.45
0.46
1.6
1.3
—
—
—
0
0
5
32
1.58
0.42
5.8
2.3
—
—
—
0
0
176
1817
0.84
0.41
76.3
11.8
—
—
—
0
0
13
171
0.75
0.41
2.0
1.6
—
—
—
0
0
179
1732
1.18
0.39
100.6
12.4
39.3
23.7
mg/l
9.59
171
1369
7
97
0.71
0.31
1.4
1.1
—
138.8
—
0
37
180
1845
0.87
0.31
42.1
9.9
31.4
27.4
u/l
1.16
174
1780
5
40
1.26
0.22
1.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
5.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
7.1
—
0
12
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
10
118
0.84
0.14
2.3
2.5
—
15.9
—
0
5
9
107
0.83
0.13
1.4
1.3
—
37.0
—
0
10
153
1556
0.95
0.11
5.9
4.4
2.0
1.9
mu/l
0.17
136
1379
5
60
0.83
0.08
1.2
1.1
—
—
—
0
0
14
127
1.11
0.08
1.4
1.5
—
—
—
0
0
7
80
0.87
0.07
1.0
1.1
—
—
—
0
0
158
1563
1.04
0.06
101.6
13.1
32.3
40.1
%
10.21
93
1106
13
125
1.04
0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
16.6
—
0
5
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
16.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: AB1_SEPSIS_FUNGAL_EXPL – Explicit fungal Sepsis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).