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ILD medications: acetylcysteine

Endpoint Browser

ILD_ASETYLCYSTEINE

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC — R05CB01

1 out of 7 registries used, show all original rules.

367

4. Check minimum number of events

Min. number of events 3
367

5. Include endpoints

None

367

6. Filter based on genotype QC (FinnGen only)

367

Control definitions (FinnGen only)

Control exclude
ILD_MEDICATIONS

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 367 154 213
Unadjusted period prevalence (%) 0.08 0.05 0.09
Median age at first event (years) 61.57 53.77 67.22

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
338
Matched controls
3378
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R05CB01
ATC
acetylcysteine; inhalant, oral
+∞
323.0
338
17
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
19.7
115.4
201
234
R03AC12
ATC
salmeterol; inhalant
46.4
92.5
113
36
H02AB06
ATC
prednisolone; systemic
11.0
87.2
236
587
R03DA04
ATC
theophylline; systemic, rectal
19.0
83.7
137
117
R03BB01
ATC
ipratropium bromide; inhalant
16.3
69.8
120
110
R03BA05
ATC
fluticasone; inhalant
11.5
67.2
141
197
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
11.3
60.4
126
169
H02AB07
ATC
prednisone; oral
12.8
57.0
109
121
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
8.8
56.5
140
250
R03AK06
ATC
salmeterol and fluticasone; inhalant
10.2
56.5
125
184
R03BA02
ATC
budesonide; inhalant
10.1
56.1
125
186
J45.9
ICD-10 Finland
Asthma, unspecified
10.1
53.6
118
170
H02AB04
ATC
methylprednisolone; systemic
11.9
52.7
104
121
R03AC02
ATC
salbutamol; inhalant
5.6
47.8
218
829
R03BA01
ATC
beclometasone; inhalant
8.0
41.7
105
180
R03DC03
ATC
montelukast; oral
10.1
37.5
79
99
J45.1
ICD-10 Finland
Nonallergic asthma
17.0
34.7
56
39
R03AC03
ATC
terbutaline; inhalant
7.6
34.5
88
150
J01AA02
ATC
doxycycline; systemic
5.7
34.4
295
1844
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
10.0
33.0
69
84
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
16.7
30.3
49
34
J01FA06
ATC
roxithromycin; oral
3.9
30.2
180
761
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
60.6
28.7
33
6
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
18.5
28.5
44
27
R03BB04
ATC
tiotropium bromide; inhalant
6.2
27.7
81
163
R03AC13
ATC
formoterol; inhalant
12.3
27.1
50
47
J45.0
ICD-10 Finland
Predominantly allergic asthma
13.2
23.7
42
36
J46
ICD-10 Finland
Status asthmaticus
28.7
21.7
29
11
R03DC01
ATC
zafirlukast; oral
21.8
20.8
30
15
R05FB02
ATC
cough suppressants and expectorants
3.0
20.0
173
875
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
8.3
19.4
44
60
J47
ICD-10 Finland
Bronchiectasis
25.7
17.6
24
10
R03AK07
ATC
formoterol and budesonide; inhalant
4.5
17.0
64
166
R05CB02
ATC
bromhexine; systemic
10.0
16.6
33
36
J96.1
ICD-10 Finland
Chronic respiratory failure
13.8
16.5
28
22
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.5
15.8
81
276
A01AB09
ATC
miconazole; local oral
4.5
15.2
56
142
J01FA10
ATC
azithromycin; systemic
2.6
15.1
153
812
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
15.0
147
766
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
83.8
14.7
16
*
J01DA01
ATC
[U] cefalexin; systemic
2.5
14.5
226
1502
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.6
14.3
70
228
R05DA20
ATC
opium alkaloids and derivatives - combinations
2.9
14.3
102
436
J01FA09
ATC
clarithromycin; systemic
3.0
14.2
95
389
R06AE07
ATC
cetirizine; oral
2.7
14.2
126
616
A02BA02
ATC
ranitidine; systemic
2.8
14.1
106
467
49300
ICD-8 Finland
Asthma, bronchiale
12.2
14.0
25
22
R01AD08
ATC
fluticasone; nasal
3.1
13.9
87
340
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.5
12.8
135
714
J01DA06
ATC
[U] cefuroxime; systemic
3.4
12.4
67
232
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
16.7
12.3
19
12
J45
ICD-10 Finland
Asthma
5.7
12.2
35
67
J45.8
ICD-10 Finland
Mixed asthma
14.1
12.1
20
15
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
48.5
12.0
14
*
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
19.8
11.7
17
9
R03BB02
ATC
oxitropium bromide; inhalant
14.3
11.6
19
14
J01MA14
ATC
moxifloxacin; systemic
4.7
11.3
39
92
J01FA01
ATC
erythromycin; systemic
3.6
10.8
50
155
R05CB03
ATC
carbocisteine; oral
7.4
10.8
25
36
A01AB10
ATC
natamycin; local oral
6.8
10.5
26
41
A01AB04
ATC
amphotericin B; local oral
4.7
10.4
35
81
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
19.5
10.3
15
8
R03BC03
ATC
nedocromil; inhalant
5.1
10.1
31
65
N05BA01
ATC
diazepam; systemic, rectal
2.9
9.6
63
251
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
12.8
9.5
16
13
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.2
9.4
52
184
M09AA72
ATC
quinine, combinations with psycholeptics; systemic
4.0
9.3
37
101
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
5.0
9.3
29
62
R01BA52
ATC
pseudoephedrine, combinations; oral
2.4
9.0
86
420
J02AC01
ATC
fluconazole; systemic
2.2
8.9
105
566
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.7
8.8
38
112
C01AA05
ATC
digoxin; systemic
2.4
8.7
83
405
C03CA01
ATC
furosemide; systemic
2.0
8.7
167
1107
M05BA04
ATC
alendronic acid; oral
3.4
8.6
41
130
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
20.7
8.5
12
6
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
+∞
8.4
8
*
J01DA09
ATC
[U] cefadroxil; inhalant, oral
2.3
8.3
90
467
A07AA02
ATC
nystatin; oral
3.9
8.0
32
88
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.1
8.0
30
78
R05DB05
ATC
pentoxyverine; oral, rectal
5.1
7.9
24
50
N02AC04
ATC
dextropropoxyphene; oral
3.7
7.8
33
96
J01FA15
ATC
telithromycin; oral
3.8
7.7
32
91
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.9
7.6
141
908
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.2
7.5
89
478
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.1
7.5
96
536
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
16.2
7.3
11
7
R01AD05
ATC
budesonide; nasal
4.0
7.3
28
75
A06AD11
ATC
lactulose; oral
2.1
7.2
87
472
M01CB01
ATC
sodium aurothiomalate; parenteral
30.7
7.2
9
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
20.5
7.2
10
5
R03DA05
ATC
aminophylline; systemic, rectal
9.1
7.1
14
16
R05FA02
ATC
opium derivatives and expectorants; systemic
1.9
6.9
131
846
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
40.9
6.8
8
*
L04AX01
ATC
azathioprine; systemic
40.9
6.8
8
*
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
17.1
6.8
10
6
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
17.1
6.8
10
6
C08DA01
ATC
verapamil; systemic
3.6
6.7
29
86
R05CA10
ATC
expectorants - combinations
6.7
6.7
16
25
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
8.1
6.7
14
18
R96
ICPC
Asthma
3.8
6.7
27
76
R03AK08
ATC
formoterol and beclometasone; inhalant
10.3
6.6
12
12
N05CF01
ATC
zopiclone; oral
1.9
6.6
134
883
A02BA04
ATC
nizatidine; systemic
2.6
6.5
48
203
J01MA12
ATC
levofloxacin; systemic
2.2
6.5
71
367
R05DB20
ATC
other cough suppressants - combinations
3.7
6.5
27
78
R06AX12
ATC
terfenadine; oral
5.1
6.5
19
39
R03AK
ATC
Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
71.1
6.4
7
*
N06AB03
ATC
fluoxetine; oral
2.7
6.4
42
167
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
8.4
6.4
13
16
R03AK11
ATC
formoterol and fluticasone; inhalant
11.3
6.3
11
10
C03DA01
ATC
spironolactone; oral
2.4
6.3
55
255
N02AX02
ATC
tramadol; systemic, rectal
1.8
6.3
128
839
L04AA13
ATC
leflunomide; oral
+∞
6.3
6
*
51899
ICD-8 Finland
Bronchiectasis
27.2
6.3
8
*
H02AB09
ATC
hydrocortisone; systemic
27.2
6.3
8
*
R01AD01
ATC
beclometasone; nasal
2.6
6.2
44
183
G47.3
ICD-10 Finland
Sleep apnoea
2.6
6.2
46
195
R03DA54
ATC
theophylline, combinations excl. psycholeptics; systemic
5.9
6.2
16
28
P01BA02
ATC
hydroxychloroquine; oral
5.9
6.2
16
28
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
7.9
6.2
13
17
N05AA02
ATC
levomepromazine; systemic
4.1
6.1
22
56
J01DA08
ATC
[U] cefaclor; oral
3.0
6.1
34
120
R95
ICPC
Chron obstructive pulmonary disease
6.2
6.1
15
25
M02AA07
ATC
piroxicam; topical
1.8
6.0
123
803

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
19
10
19.98
24.08
5.4
1.6
—
—
—
0
0
13
26
5.15
6.27
4.8
2.9
—
—
—
0
0
148
1978
0.58
6.04
5.5
4.8
6.3
6.1
mmol/l
0.42
130
1740
103
1501
0.56
5.66
5.4
4.1
—
—
—
0
0
25
89
2.94
5.53
4.2
1.6
9.9
10.1
g/l
0.10
25
72
170
2166
0.60
5.46
32.9
18.2
4.0
4.0
mmol/l
0.06
165
2077
164
2107
0.60
5.44
27.9
14.4
—
—
—
0
0
44
214
2.20
5.14
4.7
3.4
5.8
5.8
kpa
0.02
44
203
169
2141
0.61
5.13
14.2
8.7
26.0
23.0
u/l
0.71
163
2028
26
103
2.64
4.74
2.0
1.4
—
—
—
0
0
21
74
2.95
4.74
2.3
1.5
1.3
1.7
g/l
0.33
21
58
155
1981
0.62
4.66
5.2
5.1
2.6
2.6
mmol/l
0.27
135
1760
38
185
2.18
4.44
4.1
2.6
4.1
4.0
kpa
0.06
38
175
40
203
2.09
4.21
2.8
1.3
—
—
—
0
0
27
117
2.41
4.12
3.7
2.8
25.0
25.0
mmol/l
0.01
27
112
56
326
1.85
3.99
7.4
3.0
—
—
—
0
0
149
1881
0.65
3.91
4.8
4.4
1.6
1.5
mmol/l
1.05
130
1672
152
1902
0.66
3.75
4.7
4.5
4.6
4.5
mmol/l
1.29
136
1709
137
1741
0.66
3.58
32.3
16.0
35.0
37.8
%
1.41
94
1082
145
1821
0.66
3.56
4.4
4.0
1.2
1.2
mmol/l
0.03
130
1599
169
2053
0.67
3.46
29.5
14.3
25.8
27.1
mg/l
0.18
148
1610
154
1893
0.68
3.27
7.6
6.2
42.1
41.2
mmol/mol
0.34
136
1719
14
49
2.93
3.22
3.1
2.5
—
—
—
0
0
20
85
2.43
3.21
3.4
2.6
—
—
—
0
0
25
119
2.18
3.12
5.2
2.4
0.3
0.5
%
—
9
36
40
228
1.85
3.06
2.5
1.7
—
—
—
0
0
24
115
2.16
2.96
2.3
1.4
—
—
—
0
0
23
111
2.14
2.79
5.1
2.4
0.0
0.3
%
—
7
32
40
235
1.79
2.79
10.8
5.1
1.9
1.4
mmol/l
0.30
33
178
24
118
2.11
2.78
5.3
2.4
0.0
0.1
%
—
9
35
5
6
8.43
2.75
3.4
3.2
75.1
56.2
%
—
5
6
6
10
6.08
2.71
1.2
1.0
—
—
—
0
0
19
86
2.28
2.68
7.5
4.7
—
—
—
0
0
155
1864
0.71
2.67
5.7
4.6
2.0
2.7
mu/l
0.53
139
1625
21
101
2.14
2.58
4.9
2.5
0.6
0.5
%
—
5
27
26
136
1.98
2.58
7.3
3.2
—
—
—
0
0
116
904
1.41
2.39
8.8
3.2
0.2
0.2
e9/l
0.01
110
771
113
878
1.41
2.36
8.3
3.0
0.0
0.0
e9/l
0.08
106
732
115
897
1.41
2.35
8.8
3.1
1.8
1.9
e9/l
0.46
108
770
112
872
1.41
2.31
8.4
3.0
0.7
0.6
e9/l
2.94
105
725
12
49
2.50
2.12
2.8
2.1
—
—
—
0
0
27
157
1.78
1.99
3.3
4.1
96.7
92.7
ng/l
0.06
22
136
5
11
4.59
1.94
5.6
1.0
—
—
—
0
0
5
11
4.59
1.94
5.6
1.0
—
—
—
0
0
5
11
4.59
1.94
5.6
1.0
—
—
—
0
0
5
11
4.59
1.94
5.6
1.0
—
—
—
0
0
28
166
1.74
1.94
13.3
6.0
—
—
—
0
0
6
18
3.37
1.75
1.0
1.2
—
—
—
0
0
7
24
2.95
1.73
2.3
1.8
4.9
5.0
e9/l
—
7
24
10
42
2.42
1.69
1.0
1.1
—
—
—
0
0
11
49
2.28
1.65
1.3
1.1
—
—
—
0
0
76
585
1.38
1.65
7.8
2.8
—
—
—
0
0
42
289
1.51
1.64
2.8
2.0
—
—
—
0
0
6
20
3.03
1.58
1.3
1.8
—
—
—
0
0
7
27
2.62
1.52
2.6
1.9
61.9
59.4
%
—
7
27
23
140
1.69
1.49
2.0
1.5
—
—
—
0
0
45
613
0.70
1.47
2.6
2.9
6.0
6.8
mmol/l
0.93
37
491
23
141
1.67
1.45
7.4
4.0
—
—
—
0
0
5
16
3.15
1.44
1.4
1.1
—
—
—
0
0
35
494
0.68
1.39
1.7
1.6
1.2
1.3
mmol/l
0.20
29
396
15
82
1.86
1.37
14.8
5.9
—
—
—
0
0
19
115
1.69
1.27
2.2
1.4
—
—
—
0
0
74
592
1.31
1.25
2.7
2.1
3.3
3.3
mg/l
0.07
62
501
16
262
0.59
1.24
1.9
1.3
—
—
—
0
0
18
110
1.67
1.17
2.3
1.4
—
—
—
0
0
8
39
2.07
1.16
2.0
1.8
29.4
33.9
umol/l
—
8
29
37
499
0.71
1.15
4.1
3.0
2.5
2.5
mmol/l
0.57
31
423
32
227
1.45
1.12
1.2
1.3
—
—
—
0
0
19
121
1.60
1.08
15.9
6.2
0.8
0.7
%
0.21
19
121
48
612
0.75
1.05
2.5
3.0
1550.2
160.7
mg/l
0.44
28
386
131
1482
0.82
1.04
7.0
5.0
153.1
5295.4
e6/l
—
7
41
5
22
2.29
1.03
1.0
1.3
—
—
—
0
0
122
1062
1.22
1.02
11.2
6.4
4.8
4.1
e9/l
2.22
117
900
19
123
1.57
1.01
15.7
6.0
1.4
1.4
%
0.02
19
123
50
391
1.32
1.01
1.9
1.5
1.7
1.3
mg/l
0.22
40
310
25
174
1.47
0.98
11.0
4.6
1.2
1.4
mmol/l
1.05
25
164
7
36
1.96
0.97
1.7
1.1
0.7
0.8
nmol/l
—
7
28
93
793
1.23
0.94
4.4
3.4
—
—
—
0
0
16
102
1.59
0.92
6.5
4.0
24.7
23.7
mmol/l
0.75
16
92
66
793
0.80
0.92
2.9
2.3
—
—
—
0
0
9
154
0.57
0.90
2.0
1.5
—
—
—
0
0
137
1524
0.84
0.88
4.5
3.8
15.3
15.1
pmol/l
0.38
121
1322
58
475
1.26
0.84
8.3
5.5
—
—
—
0
0
57
689
0.80
0.84
6.6
4.0
—
—
—
0
0
6
32
1.89
0.82
6.8
2.4
—
—
—
0
0
6
32
1.89
0.82
2.5
1.7
62.4
55.5
%
—
6
32
78
669
1.21
0.75
5.9
3.7
—
—
—
0
0
9
54
1.68
0.75
1.9
1.6
—
—
—
0
0
22
159
1.41
0.74
1.4
1.3
384.0
427.9
titre
—
5
33
9
55
1.65
0.74
2.7
3.5
—
—
—
0
0
131
1439
0.86
0.68
6.7
4.2
—
—
—
0
0
38
464
0.80
0.63
4.4
3.2
316.0
124.4
ng/l
0.28
32
394
35
283
1.26
0.59
2.1
1.3
1.9
2.6
g/l
1.50
28
141
57
652
0.85
0.50
2.8
3.7
9.4
9.2
mg/mmol
0.01
37
400
52
597
0.85
0.48
1.8
1.6
30.2
20.7
nmol/l
0.59
45
495
22
173
1.29
0.47
1.5
1.4
84.2
106.6
ug/g
0.32
16
131
23
183
1.27
0.46
1.7
2.0
82.6
61.8
e9/l
1.31
15
143
15
195
0.76
0.42
1.5
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
260.1
—
0
10
0
16
0.00
0.41
0.0
1.3
—
67.6
—
0
10
14
182
0.76
0.40
5.0
4.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.6
—
—
—
0
0
153
1618
0.91
0.39
10.0
5.8
80.1
84.2
u/l
0.33
145
1470
72
651
1.13
0.39
3.2
2.1
—
—
—
0
0
5
36
1.39
0.38
1.0
1.0
—
—
—
0
0
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
9
68
1.33
0.38
1.3
1.3
—
—
—
0
0
6
42
1.44
0.35
3.5
2.1
—
—
—
0
0
6
43
1.40
0.35
1.3
1.7
—
—
—
0
0
10
73
1.38
0.35
8.4
3.5
3.7
4.0
mmol/l
—
10
68
24
200
1.21
0.34
2.4
2.7
151.9
215.5
ng/l
0.50
24
183
143
1505
0.92
0.32
6.7
2.9
16.0
14.7
mm/h
0.44
133
1326
31
355
0.86
0.30
1.4
1.2
1.9
1.3
u/ml
—
6
95
75
810
0.91
0.29
5.5
3.7
104.9
221.7
e6/l
0.62
61
588
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
88
820
1.10
0.29
4.3
2.5
122.9
132.0
ug/l
0.20
82
729
73
785
0.91
0.26
5.3
2.9
2.3
2.4
mmol/l
0.21
59
668
55
598
0.91
0.25
6.4
4.3
0.0
0.0
estimate
0.00
12
169
11
87
1.27
0.24
7.7
4.0
1.5
1.4
mmol/l
0.13
11
87
6
83
0.72
0.24
1.0
1.3
—
20.8
—
0
5
57
617
0.91
0.24
4.2
3.2
—
—
—
0
0
5
40
1.25
0.22
2.2
1.5
—
—
—
0
0
97
1022
0.93
0.22
6.3
4.1
0.0
0.0
estimate
0.00
13
187
67
716
0.92
0.21
4.7
3.3
36.0
180.9
e6/l
0.91
56
546
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
14.8
—
0
5
8
102
0.78
0.21
1.6
3.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
53
491
1.09
0.20
4.6
2.9
562.7
542.8
mosm/kgh2o
0.30
48
415
0
14
0.00
0.20
0.0
2.6
—
7.0
—
0
9
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.9
—
—
—
0
0
22
194
1.14
0.19
4.0
3.2
—
—
—
0
0
133
1282
1.06
0.18
8.2
3.9
7.0
6.9
mmol/l
0.07
126
1187
98
1025
0.94
0.18
10.3
5.5
0.0
0.0
estimate
0.00
13
177
6
79
0.76
0.15
1.8
2.4
—
—
—
0
0
47
498
0.94
0.13
6.2
4.5
1.0
1.0
kg/l
—
7
76
100
1035
0.95
0.13
6.6
4.1
0.0
0.0
estimate
0.00
13
174
94
973
0.95
0.12
10.8
11.4
1.1
1.4
inr
2.03
18
270
11
95
1.16
0.11
11.6
3.3
—
—
—
0
0
83
858
0.96
0.10
15.1
8.5
0.0
0.0
e9/l
1.33
71
697
37
350
1.06
0.09
2.7
1.5
28.6
29.7
s
0.63
37
340
5
48
1.04
0.09
1.4
1.4
—
—
—
0
0
26
243
1.08
0.09
1.3
1.2
25.3
22.1
iu/ml
—
7
79
7
66
1.06
0.08
1.9
1.2
—
—
—
0
0
7
66
1.06
0.08
1.3
1.7
34.2
32.2
mg/l
—
7
53
7
66
1.06
0.08
1.3
1.7
29.4
149.4
mg/l
—
7
53
56
540
1.04
0.08
2.0
1.8
1212.0
1199.3
nmol/l
0.03
41
402
6
70
0.85
0.07
1.7
1.5
—
—
—
0
0
42
437
0.96
0.07
1.1
1.3
—
—
—
0
0
13
142
0.91
0.06
1.7
1.5
—
—
—
0
0
9
104
0.86
0.06
1.3
1.2
—
—
—
0
0
92
940
0.97
0.06
5.5
4.2
164.0
78.5
ng/l
0.30
75
726
63
647
0.97
0.06
4.5
3.2
0.3
0.6
e6/l
1.27
51
485
67
683
0.98
0.03
5.8
3.3
7.4
7.4
ph
0.10
13
129
49
502
0.97
0.03
3.5
2.6
8.2
5.8
e6/l
0.32
44
444
55
562
0.97
0.03
3.1
3.3
—
—
—
0
0
23
222
1.04
0.02
1.2
1.2
1.2
2.3
u/ml
—
9
71
49
481
1.02
0.02
4.9
2.3
10319.7
10378.8
umol/l
0.00
44
394
10
107
0.93
0.02
1.6
1.3
—
—
—
0
0
12
127
0.94
0.01
1.2
1.1
—
—
—
0
0
12
127
0.94
0.01
3.7
2.5
—
—
—
0
0
54
532
1.02
0.01
2.0
1.8
498.8
448.3
pmol/l
0.55
43
420
58
572
1.02
0.01
7.9
3.7
—
—
—
0
0
98
972
1.01
0.01
2.2
2.1
99.8
94.2
pmol/l
0.46
45
481
47
476
0.99
0.00
5.7
4.0
—
—
—
0
0
112
1114
1.01
0.00
11.4
4.8
1.2
1.2
mmol/l
0.01
93
901
19
188
1.01
0.00
9.5
3.5
—
—
—
0
0
15
151
0.99
0.00
1.6
1.4
—
—
—
0
0
100
1002
1.00
0.00
11.4
4.5
1.2
1.2
mmol/l
0.88
90
884
6
64
0.94
0.00
4.8
3.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
2.3
—
0
5
7
70
1.00
0.00
7.6
11.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.0
1.1
—
—
—
0
0
6
63
0.95
0.00
1.0
1.3
—
—
—
0
0
17
170
1.00
0.00
4.8
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
7.2
—
0.7
—
0
5
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
6.8
—
0
7
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
16.4
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
2.1
—
0
8
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
53.0
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ILD_ASETYLCYSTEINE – ILD medications: acetylcysteine

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).