Other bursitis of knee

M13_BURSITISKNEEOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M70.5
  • Hospital discharge: ICD-9 7266B|7266C|7266X
  • Cause of death: ICD-10 M70.5
  • Cause of death: ICD-9 7266B|7266C|7266X

2 out of 7 registries used, show all original rules.

508

4. Check minimum number of events

None

508

5. Include endpoints

None

508

6. Filter based on genotype QC (FinnGen only)

508

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M70
Name in latin
Alia bursitis genus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3713 1232 2461
Only index persons 3540 1170 2370
Unadjusted period prevalence (%)
Whole population 0.06 0.04 0.07
Only index persons 0.07 0.04 0.09
Median age at first event (years)
Whole population 46.67 49.87 45.16
Only index persons 46.57 49.25 45.25

-FinnGen-

Key figures

All Female Male
Number of individuals 508 199 309
Unadjusted period prevalence (%) 0.11 0.07 0.14
Median age at first event (years) 51.39 51.58 51.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
445
Matched controls
4448
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M70.5
ICD-10 Finland
Other bursitis of knee
3672.0
323.0
382
7
M70.4
ICD-10 Finland
Prepatellar bursitis
35.7
37.5
48
15
NGM20
NOMESCO Finland
Excision of synovial ganglion of knee or lower leg
+∞
32.7
31
*
7266X
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of knee[ENTHESOPATHIA GENUS ALIA DEFINITA SEU NUD]
+∞
32.7
31
*
M79.6
ICD-10 Finland
Pain in limb
3.8
31.8
175
655
M25.5
ICD-10 Finland
Pain in joint
3.5
26.9
158
608
J01DB01
ATC
cefalexin; oral
3.8
24.0
392
2936
N02AX02
ATC
tramadol; systemic, rectal
2.8
23.1
213
1091
M03BX02
ATC
tizanidine; oral
2.6
19.7
293
1910
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
19.6
226
1281
M01AH05
ATC
etoricoxib; oral
2.4
17.2
272
1768
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.5
16.8
87
292
7266C
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of knee[TENDINITIS SEU BURSITIS REGIONIS LIG GENUS COLL LAT]
+∞
16.8
16
*
7266B
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of knee[TENDINITIS SEU BURSITIS REGIONIS LIG GENUS COLL MED]
+∞
16.8
16
*
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
10.6
15.7
30
30
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.9
14.1
97
392
M03BC01
ATC
orphenadrine (citrate); systemic
2.6
14.0
120
554
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.7
14.0
65
199
M71.0
ICD-10 Finland
Abscess of bursa
55.2
13.9
16
*
M54.5
ICD-10 Finland
Low back pain
2.3
13.5
149
785
M01AB05
ATC
diclofenac; systemic, rectal
2.2
13.4
304
2208
N02BE01
ATC
paracetamol; systemic, rectal
2.6
13.4
380
3080
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
13.2
168
947
M77.0
ICD-10 Finland
Medial epicondylitis
19.8
13.0
19
10
M54.4
ICD-10 Finland
Lumbago with sciatica
3.0
12.9
80
302
N03AX16
ATC
pregabalin; oral
2.6
12.5
102
455
A02BC05
ATC
esomeprazole; systemic
2.2
12.5
179
1057
M13.9
ICD-10 Finland
Arthritis, unspecified
4.5
12.4
44
105
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
4.6
12.2
43
102
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
9.1
12.2
25
29
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
7.1
12.1
29
43
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.3
12.0
45
114
J01FF01
ATC
clindamycin; systemic
2.3
11.9
140
753
L15
ICPC
Knee symptom/complaint
2.5
11.6
99
452
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
3.8
11.5
49
140
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
11.2
152
869
M65.3
ICD-10 Finland
Trigger finger
11.6
11.1
20
18
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.9
10.7
66
248
SPAT1153
SPAT
Removal of sutures
2.1
10.7
142
797
M01AC06
ATC
meloxicam; systemic, rectal
2.1
10.5
157
929
M01AX05
ATC
glucosamine; oral
2.6
10.4
80
344
R03AC02
ATC
salbutamol; inhalant
1.9
10.2
218
1474
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.6
10.1
76
322
A02BC02
ATC
pantoprazole; systemic
1.9
10.0
272
2003
WX320
NOMESCO Finland
Spinalanesthesy
2.3
9.9
103
518
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.0
9.9
39
104
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.6
9.9
45
136
M70.6
ICD-10 Finland
Trochanteric bursitis
3.7
9.8
42
121
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
13.8
9.7
16
12
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.0
9.7
57
208
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
56.2
9.7
11
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
9.7
49
161
L16
ICPC
Ankle symptom/complaint
3.2
9.6
51
174
H02AB06
ATC
prednisolone; systemic
1.9
9.5
193
1270
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
9.4
116
628
N03AX12
ATC
gabapentin; oral
2.7
9.1
63
254
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
19.1
9.0
13
7
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
8.9
127
729
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
8.9
218
1524
A46
ICD-10 Finland
Erysipelas
2.5
8.8
73
324
R06.0
ICD-10 Finland
Dyspnoea
2.2
8.8
103
543
M22.4
ICD-10 Finland
Chondromalacia patellae
5.9
8.6
23
41
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
8.5
114
636
J01FA06
ATC
roxithromycin; oral
1.9
8.5
167
1077
R06AE07
ATC
cetirizine; oral
1.8
8.4
178
1179
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.9
8.2
33
90
R05
ICD-10 Finland
Cough
2.2
8.2
88
445
J01DA01
ATC
[U] cefalexin; systemic
1.8
8.2
262
1975
S18
ICPC
Laceration/cut
1.8
8.1
176
1168
M67.4
ICD-10 Finland
Ganglion
6.5
8.1
20
32
M79.1
ICD-10 Finland
Myalgia
2.9
8.1
48
177
1220
FHL
Arthroscopy
4.7
8.0
26
58
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
7.9
85
429
M01AH01
ATC
celecoxib; oral (coxibs)
2.3
7.8
74
351
ZXA05
NOMESCO Finland
Left side
2.0
7.8
107
598
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
7.8
46
169
R51.80
ICD-10 Finland
Headache
2.4
7.7
64
286
M76.9
ICD-10 Finland
Enthesopathy of lower limb, unspecified
25.5
7.6
10
*
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
9.1
7.6
15
17
M01AE02
ATC
naproxen; oral, rectal
1.7
7.6
232
1709
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.1
7.5
28
72
J01CA04
ATC
amoxicillin; systemic
1.8
7.4
336
2786
M02AA10
ATC
ketoprofen; topical
2.3
7.4
71
340
M71.1
ICD-10 Finland
Other infective bursitis
+∞
7.3
7
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.7
7.3
49
192
M71.9
ICD-10 Finland
Bursopathy, unspecified
16.1
7.3
11
7
R42
ICD-10 Finland
Dizziness and giddiness
2.1
7.3
85
445
M70.2
ICD-10 Finland
Olecranon bursitis
5.2
7.2
21
42
M19.9
ICD-10 Finland
Arthrosis, unspecified
5.5
7.2
20
38
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
8.1
7.2
15
19
M02AA07
ATC
piroxicam; topical
1.8
7.1
142
911
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
6.5
7.0
17
27
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.2
7.0
71
350
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.9
6.9
40
145
M03BC51
ATC
orphenadrine, combinations; systemic
1.9
6.9
111
660
M79.7
ICD-10 Finland
Fibromyalgia
11.2
6.8
12
11
M70.0
ICD-10 Finland
Chronic crepitant synovitis of hand and wrist
40.7
6.8
8
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.1
6.7
20
41
1225
FHL
Arthroscopy and other therapeutic procedure
8.0
6.7
14
18
G44.2
ICD-10 Finland
Tension-type headache
2.5
6.6
52
226
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
6.6
176
1229
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
14.6
6.4
10
7
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.7
6.4
44
176
J01MA12
ATC
levofloxacin; systemic
2.1
6.4
79
422
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
6.3
36
129
L13
ICPC
Hip symptom/complaint
2.3
6.3
58
274
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
18.3
6.3
9
5
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
+∞
6.3
6
*
M01AB01
ATC
indometacin; systemic, rectal
2.9
6.3
37
137
A02BC03
ATC
lansoprazole; oral
1.8
6.2
116
720
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.6
6.2
43
174
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.5
6.2
27
81
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
6.1
71
370
S50.0
ICD-10 Finland
Contusion of elbow
6.2
6.0
15
25
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
6.0
56
265
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
6.0
46
198

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
145
512
3.56
33.76
2.4
2.2
—
—
—
0
0
36
45
8.53
27.20
1.4
1.5
—
—
—
0
0
45
73
6.67
27.09
1.5
1.7
7458.4
15988.1
e6/l
0.96
25
56
32
58
5.82
17.17
1.4
1.5
—
—
—
0
0
114
512
2.58
16.16
1.4
1.2
19.3
14.4
u/ml
0.19
36
204
179
1023
2.16
14.35
4.1
4.3
—
—
—
0
0
111
552
2.29
12.31
1.5
1.2
17.7
30.2
iu/ml
1.60
37
182
305
2214
1.94
11.78
8.0
9.8
4.1
4.1
e9/l
0.08
267
1954
166
997
1.99
11.14
2.3
2.8
337.0
8664.0
umol/l
4.84
148
881
276
1962
1.89
11.11
6.5
6.3
0.2
0.2
e9/l
0.62
242
1744
271
1947
1.84
10.24
6.4
6.0
2.4
1.9
e9/l
0.40
237
1732
251
1762
1.84
10.22
4.6
4.0
—
—
—
0
0
266
1904
1.83
10.14
6.5
5.9
0.0
0.0
e9/l
0.03
229
1669
172
1078
1.90
9.98
2.1
2.0
206.2
464.0
u/l
1.24
164
1018
264
1899
1.81
9.77
6.4
5.9
0.6
0.6
e9/l
0.65
227
1660
16
27
6.09
9.17
1.4
1.5
8186.4
310351.5
e6/l
—
10
17
301
2280
1.79
9.10
4.8
4.8
6.5
6.8
mmol/l
1.75
288
2129
459
4005
2.51
9.02
18.4
13.0
25.8
25.6
mg/l
0.03
392
3122
352
2807
1.83
8.81
4.8
3.6
12.2
11.5
mm/h
0.38
332
2606
365
2956
1.83
8.52
7.5
7.9
80.7
78.3
u/l
0.28
352
2788
12
16
7.66
8.44
1.4
1.4
—
—
—
0
0
252
1866
1.70
7.81
6.9
6.1
27.1
28.0
%
0.65
236
1754
328
2616
1.72
7.62
4.3
3.9
—
—
—
0
0
244
1803
1.68
7.53
6.8
6.0
3.0
2.9
%
0.55
230
1694
247
1832
1.68
7.51
6.5
5.9
57.3
56.9
%
0.18
232
1732
244
1814
1.66
7.28
7.1
6.3
8.8
8.9
%
0.10
230
1716
237
1751
1.66
7.23
6.8
6.1
0.7
0.7
%
0.27
223
1648
260
1975
1.65
7.05
5.5
7.0
11.8
11.7
umol/l
0.02
245
1877
13
24
5.53
6.80
2.0
1.3
44.9
27.0
%
—
8
15
80
445
1.95
6.39
1.9
1.5
—
—
—
0
0
211
1554
1.61
6.26
13.2
9.3
1.4
1.2
inr
0.73
60
449
171
1204
1.63
6.05
2.2
2.3
—
—
—
0
0
165
1154
1.64
5.99
2.8
2.4
55.8
59.7
u/l
0.80
150
1069
463
4197
2.16
5.93
18.9
15.1
4.0
4.0
mmol/l
0.42
458
4081
79
449
1.90
5.91
1.5
1.3
658.7
381.2
titre
0.38
15
85
147
1004
1.65
5.84
3.8
3.4
1651.7
1392.0
ng/l
0.30
122
865
141
957
1.66
5.72
3.4
2.7
—
—
—
0
0
478
4402
2.45
5.66
11.1
9.8
28.5
28.7
u/l
0.11
463
4250
341
2853
1.59
5.62
3.9
3.5
14.8
14.7
pmol/l
0.17
312
2592
176
1269
1.59
5.56
6.3
6.1
—
—
—
0
0
11
21
5.33
5.54
1.0
1.0
—
—
—
0
0
460
4181
2.06
5.51
18.9
15.0
139.7
139.7
mmol/l
0.15
454
4069
120
790
1.68
5.45
3.3
1.7
1.3
1.2
mg/l
0.15
89
608
198
1473
1.56
5.44
2.0
1.9
95.8
94.8
pmol/l
0.10
105
810
236
1829
1.54
5.39
4.7
4.5
0.0
0.0
estimate
0.00
43
341
466
4269
2.11
5.24
16.0
12.4
—
—
—
0
0
427
3805
1.77
5.24
5.6
5.4
39.5
39.8
mmol/mol
0.21
398
3546
31
128
2.51
5.15
4.3
3.8
1.6
1.4
mmol/l
0.34
31
122
79
469
1.81
5.14
31.4
22.1
1.5
1.2
inr
0.84
12
65
14
36
3.97
5.02
1.7
1.5
61.1
61.9
%
—
9
28
75
446
1.80
4.85
5.2
8.3
0.7
1.1
mmol/l
0.42
59
350
209
1607
1.51
4.79
2.7
2.7
107.0
153.0
ug/l
3.17
199
1493
136
952
1.59
4.77
6.3
7.1
—
—
—
0
0
147
1049
1.56
4.74
3.5
2.9
0.6
0.5
e6/l
0.06
112
796
211
1644
1.48
4.45
5.2
6.4
1.2
1.2
mmol/l
0.01
193
1497
76
466
1.74
4.43
1.3
1.2
—
—
—
0
0
233
1853
1.48
4.43
3.5
3.2
0.0
0.0
estimate
0.00
45
319
231
1834
1.48
4.43
3.3
3.2
0.0
0.0
estimate
0.00
43
331
175
1318
1.50
4.34
4.3
3.5
46.5
81.8
e6/l
0.79
132
953
125
877
1.56
4.30
2.3
2.0
2.7
3.0
mg/l
0.76
112
755
50
272
1.93
4.27
2.4
3.1
66.2
66.9
g/l
0.25
45
249
490
4631
2.64
4.25
25.3
18.9
252.8
246.8
e9/l
1.32
484
4518
490
4633
2.63
4.21
25.1
18.8
30.4
30.4
pg
0.58
485
4563
205
1602
1.47
4.20
4.8
5.2
34.4
35.8
g/l
2.59
186
1500
490
4634
2.62
4.19
25.2
18.9
4.5
4.6
e12/l
0.81
484
4514
400
3567
1.57
4.17
4.8
4.1
1.8
1.9
mu/l
1.05
366
3259
490
4635
2.61
4.17
25.3
18.9
6.9
6.7
e9/l
0.69
483
4511
105
712
1.60
4.16
3.1
2.7
546.5
586.6
mosm/kgh2o
0.93
91
619
74
459
1.72
4.14
1.4
1.5
—
—
—
0
0
139
1006
1.53
4.14
3.5
2.9
—
—
—
0
0
227
1820
1.45
4.02
6.1
7.4
1.2
1.2
mmol/l
0.33
198
1561
113
791
1.55
3.89
3.1
3.3
—
—
—
0
0
329
2837
1.45
3.87
3.8
3.6
—
—
—
0
0
182
1412
1.45
3.79
4.2
3.3
26.5
37.7
ng/l
1.01
124
963
215
1726
1.43
3.70
11.5
9.3
0.0
0.0
e9/l
0.64
172
1435
153
1154
1.47
3.67
3.8
3.0
55.2
138.0
e6/l
0.76
124
892
430
3944
1.59
3.49
4.6
4.3
5.9
6.0
mmol/l
0.61
401
3623
39
210
1.93
3.46
2.9
2.7
—
—
—
0
0
393
3542
1.48
3.41
21.3
16.3
333.1
333.8
g/l
0.84
393
3512
116
847
1.48
3.24
5.4
4.6
—
—
—
0
0
116
852
1.47
3.14
1.5
1.5
19.0
20.2
nmol/l
0.45
96
732
66
429
1.62
3.10
1.4
1.4
—
—
—
0
0
101
726
1.49
3.04
4.0
3.8
800.4
459.1
ng/l
0.23
78
585
105
767
1.47
2.91
1.3
1.2
1.3
2.1
u/ml
0.54
30
214
26
129
2.07
2.91
10.0
10.5
—
—
—
0
0
16
64
2.55
2.90
2.5
5.7
1.5
2.2
mmol/l
—
8
42
105
770
1.46
2.85
2.8
2.4
3.5
5.1
e6/l
0.78
91
680
449
4206
1.58
2.80
5.0
4.7
2.8
2.8
mmol/l
0.16
425
3908
24
119
2.07
2.70
1.2
1.1
—
—
—
0
0
17
73
2.37
2.68
1.1
1.2
—
—
—
0
0
83
589
1.49
2.66
2.2
2.6
12.7
13.8
umol/l
0.74
75
548
42
253
1.72
2.65
5.1
5.0
—
—
—
0
0
182
1491
1.34
2.55
2.1
2.0
—
—
—
0
0
15
63
2.42
2.48
6.3
3.3
4.6
4.1
e9/l
0.47
15
63
19
89
2.18
2.48
3.1
2.3
2839.1
2110.4
u/l
—
8
35
46
292
1.63
2.41
3.9
4.8
0.2
0.1
%
0.14
13
88
36
216
1.72
2.32
2.1
2.9
—
—
—
0
0
15
66
2.31
2.26
6.3
3.5
60.7
56.0
%
1.03
15
66
23
121
1.94
2.24
1.7
1.6
—
—
—
0
0
48
314
1.58
2.24
3.8
4.7
0.6
0.7
%
0.15
13
97
97
733
1.40
2.23
1.4
1.4
2.8
2.5
g/l
0.30
61
488
26
144
1.85
2.19
6.0
4.0
—
—
—
0
0
20
101
2.02
2.18
1.2
1.2
—
—
—
0
0
121
953
1.35
2.16
3.6
3.5
0.0
0.0
estimate
0.50
45
327
40
254
1.62
2.11
1.1
1.2
—
—
—
0
0
136
1098
1.33
2.05
4.3
3.6
—
—
—
0
0
32
196
1.68
1.95
5.0
11.8
23.6
24.7
mmol/l
0.98
27
189
51
350
1.51
1.95
3.3
4.0
2.2
2.1
mmol/l
0.07
42
272
14
65
2.19
1.89
1.8
2.1
—
—
—
0
0
438
4149
1.40
1.89
4.4
4.3
4.7
4.7
mmol/l
0.48
415
3879
42
278
1.56
1.89
3.9
4.8
0.0
0.0
%
—
10
77
17
86
2.01
1.87
1.5
1.3
—
—
—
0
0
424
3999
1.36
1.85
4.0
3.8
1.3
1.3
mmol/l
0.09
402
3715
409
3837
1.34
1.85
17.6
13.7
40.5
40.9
%
0.41
319
2862
436
4131
1.39
1.84
4.4
4.2
1.4
1.4
mmol/l
0.28
414
3840
15
73
2.09
1.82
4.1
3.8
—
—
—
0
0
100
785
1.34
1.82
3.4
3.5
1.0
1.0
kg/l
0.33
12
119
17
87
1.99
1.82
1.1
1.2
—
—
—
0
0
13
61
2.16
1.73
1.1
1.0
—
4.3
u/ml
—
0
16
14
68
2.09
1.71
1.0
1.0
1.3
11.6
u/ml
—
7
33
14
69
2.06
1.66
1.1
1.0
0.4
3.1
u/ml
—
5
29
145
1215
1.27
1.63
3.9
3.9
10.2
10.3
mg/mmol
0.01
95
805
5
14
3.60
1.62
4.2
2.0
—
—
—
0
0
13
63
2.09
1.61
3.2
4.0
—
—
—
0
0
146
1233
1.26
1.53
3.2
3.1
7.3
8.3
mmol/l
2.00
120
1049
22
131
1.71
1.52
1.6
1.8
185.4
212.3
pmol/l
0.60
22
125
41
285
1.48
1.51
3.8
4.5
0.6
0.5
%
—
9
73
30
195
1.57
1.49
1.2
1.3
—
—
—
0
0
80
627
1.33
1.48
1.6
1.7
1305.4
1169.0
nmol/l
0.52
61
485
45
323
1.43
1.42
5.0
9.7
—
—
—
0
0
141
1196
1.25
1.41
2.8
3.7
2.3
2.3
mmol/l
0.14
124
1070
136
1150
1.25
1.40
3.1
3.2
483.1
331.6
mg/l
0.13
91
770
7
29
2.43
1.39
1.7
1.7
6.3
6.4
mmol/l
—
7
20
24
151
1.62
1.37
1.5
1.7
—
—
—
0
0
6
23
2.63
1.37
1.0
1.2
—
—
—
0
0
22
136
1.65
1.35
2.5
1.8
—
—
—
0
0
27
176
1.56
1.34
3.3
3.8
—
—
—
0
0
9
42
2.16
1.34
1.4
1.2
—
—
—
0
0
9
42
2.16
1.34
1.1
1.5
—
—
—
0
0
9
42
2.16
1.34
1.8
1.2
—
—
—
0
0
25
161
1.58
1.31
3.0
2.8
—
—
—
0
0
18
106
1.72
1.31
1.3
1.4
280.4
299.0
ug/g
—
8
61
23
146
1.60
1.28
1.7
1.5
—
—
—
0
0
148
1699
0.82
1.26
3.0
2.7
—
—
—
0
0
23
147
1.59
1.25
2.5
1.8
—
—
—
0
0
17
100
1.72
1.25
1.4
1.2
0.2
0.3
g/l
0.41
12
92
9
45
2.02
1.24
1.9
2.5
—
—
—
0
0
5
19
2.65
1.22
1.8
5.9
—
—
—
0
0
134
1149
1.23
1.21
1.4
1.4
—
—
—
0
0
23
149
1.57
1.19
2.5
1.8
—
—
—
0
0
55
423
1.34
1.18
2.9
2.5
109.8
142.7
ug/g
0.60
48
346
62
486
1.31
1.17
1.2
1.2
—
—
—
0
0
8
39
2.07
1.15
1.3
1.6
—
—
nmol/l
—
0
0
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
18
111
1.64
1.13
4.7
2.9
—
—
—
0
0
11
58
1.92
1.13
1.1
1.5
—
—
—
0
0
53
409
1.33
1.12
1.2
1.5
—
—
—
0
0
126
1082
1.22
1.12
3.3
4.2
7.4
7.4
ph
0.42
29
189
27
185
1.49
1.11
3.6
2.5
1.3
1.2
%
0.18
27
185
7
31
2.28
1.10
1.1
1.1
—
—
—
0
0
33
237
1.42
1.07
1.4
1.2
196.8
139.1
iu/ml
—
9
98
124
1069
1.21
1.06
3.2
2.9
—
—
—
0
0
22
146
1.53
1.05
2.7
1.8
—
—
—
0
0
18
114
1.60
1.04
2.8
1.9
—
—
—
0
0
41
309
1.36
1.02
5.4
3.2
272.4
189.8
ng/l
0.53
35
278
11
61
1.82
0.99
1.1
1.2
—
—
—
0
0
5
23
2.19
0.98
1.4
1.3
—
—
—
0
0
9
52
1.74
0.92
1.3
1.2
—
—
—
0
0
29
210
1.40
0.92
3.2
2.6
0.1
0.2
e6/l
2.26
29
202
35
263
1.36
0.90
1.3
1.4
—
—
—
0
0
52
415
1.28
0.89
1.9
2.8
1.9
1.8
%
0.45
46
380
38
290
1.34
0.89
3.4
3.3
—
—
—
0
0
46
362
1.30
0.88
1.5
1.3
—
—
—
0
0
34
256
1.35
0.87
3.7
4.2
7.4
7.4
ph
—
7
30
11
66
1.68
0.79
1.1
1.2
—
—
—
0
0
63
524
1.23
0.78
2.5
2.6
22.3
24.1
%
0.53
55
444
6
34
1.77
0.76
3.0
2.4
—
—
—
0
0
7
38
1.85
0.74
1.1
1.1
—
—
—
0
0
90
781
1.19
0.73
1.9
1.7
407.6
30415846.5
pmol/l
0.96
79
674
5
25
2.01
0.73
3.2
1.7
—
—
—
0
0
5
25
2.01
0.73
1.2
1.1
—
—
—
0
0
7
39
1.81
0.72
1.6
1.6
—
—
—
0
0
9
56
1.62
0.72
4.2
2.6
—
—
—
0
0
9
57
1.59
0.71
3.4
3.5
—
—
—
0
0
5
26
1.93
0.71
2.2
2.2
490.0
505.1
min
—
5
20
14
93
1.52
0.70
4.6
2.9
—
—
—
0
0
41
330
1.26
0.69
2.2
2.3
18.8
10.0
ug/l
0.72
31
289
5
27
1.86
0.68
1.0
1.2
—
—
—
0
0
28
214
1.33
0.68
6.4
12.3
—
—
—
0
0
75
646
1.19
0.67
2.7
3.2
2.4
2.4
mmol/l
0.19
63
575
198
1834
1.13
0.66
4.6
4.3
2.0
2.4
ug/l
0.77
183
1653
5
28
1.79
0.66
1.8
1.2
—
—
—
0
0
12
78
1.55
0.66
3.8
2.3
—
—
—
0
0
7
44
1.60
0.65
1.1
1.5
—
—
—
0
0
8
51
1.58
0.60
5.5
2.9
3.9
4.0
mmol/l
—
8
51
8
51
1.58
0.60
5.5
2.9
107.3
104.5
mmol/l
—
8
51
8
51
1.58
0.60
5.5
2.9
—
—
—
0
0
0
20
0.00
0.60
0.0
5.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
134.5
—
0
20
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
8
52
1.55
0.59
1.6
1.2
—
—
—
0
0
27
342
0.78
0.59
1.4
1.4
—
—
—
0
0
21
158
1.34
0.58
1.6
1.9
1.5
1.5
g/l
0.03
16
136
6
36
1.67
0.57
1.5
1.3
—
—
—
0
0
12
82
1.47
0.55
1.8
2.6
—
—
—
0
0
78
691
1.15
0.52
1.5
1.8
—
—
—
0
0
52
450
1.17
0.47
1.5
1.7
—
—
—
0
0
16
121
1.33
0.44
1.1
1.1
—
—
—
0
0
7
51
1.38
0.44
1.1
1.3
—
—
—
0
0
7
51
1.38
0.44
1.9
2.4
32.7
34.0
pg
—
7
51
37
313
1.20
0.43
4.3
3.4
—
—
—
0
0
5
32
1.57
0.42
2.2
2.6
—
37.5
—
0
10
117
1080
1.11
0.42
2.9
2.7
0.8
0.8
ug/l
0.01
72
665
5
33
1.52
0.41
1.4
1.3
282.0
279.5
mosm/kgh2o
—
5
26
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
1165.6
—
0
15
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
35
298
1.19
0.39
2.3
3.1
84.0
70.0
e9/l
1.29
30
232
5
35
1.43
0.39
2.4
2.2
507.4
658.3
ml
—
5
23
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
—
—
0
0
5
36
1.39
0.38
28.6
14.8
2650.2
1405.1
nmol/l
—
5
36
9
124
0.72
0.35
1.2
1.5
—
—
—
0
0
6
43
1.40
0.35
4.2
6.2
7.4
7.2
mmol/l
—
6
35
6
46
1.31
0.33
1.2
2.0
2.2
1.7
mmol/l
—
6
46
47
419
1.13
0.31
2.9
4.9
9.1
42.0
ug/l
0.94
32
342
21
175
1.21
0.30
2.5
2.2
—
—
—
0
0
62
564
1.11
0.30
1.5
1.6
—
—
—
0
0
39
346
1.14
0.28
4.7
5.1
—
—
—
0
0
13
104
1.26
0.26
2.5
2.4
204.8
123.5
ug/min
—
7
64
12
96
1.26
0.24
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.4
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
50
1.20
0.19
1.0
1.1
—
—
—
0
0
32
290
1.11
0.18
1.4
1.6
—
—
—
0
0
7
61
1.15
0.17
1.1
1.8
—
—
—
0
0
7
61
1.15
0.17
1.1
1.8
—
—
—
0
0
7
61
1.15
0.17
1.1
1.8
—
—
—
0
0
7
61
1.15
0.17
1.1
1.8
—
—
—
0
0
26
288
0.90
0.17
1.3
1.4
—
—
—
0
0
5
67
0.74
0.17
1.0
1.0
1.6
1.5
g/l
—
5
56
5
68
0.73
0.17
1.2
1.3
—
—
—
0
0
56
526
1.07
0.16
1.3
1.4
—
—
—
0
0
35
324
1.09
0.14
1.5
1.7
—
—
—
0
0
10
84
1.19
0.14
1.4
1.7
—
—
—
0
0
21
189
1.12
0.14
3.4
4.7
—
—
—
0
0
12
103
1.17
0.14
5.1
4.7
—
—
—
0
0
23
211
1.09
0.11
1.5
1.7
—
—
—
0
0
23
213
1.08
0.09
1.0
1.1
—
—
—
0
0
6
58
1.03
0.08
2.8
3.5
—
—
—
0
0
6
72
0.83
0.07
1.2
1.1
—
—
—
0
0
6
72
0.83
0.07
1.2
1.1
—
—
—
0
0
10
89
1.13
0.07
2.5
4.0
—
—
—
0
0
8
91
0.88
0.07
1.5
1.5
—
—
—
0
0
44
457
0.96
0.06
1.7
1.6
—
—
—
0
0
11
120
0.91
0.05
1.1
1.2
—
—
—
0
0
27
260
1.04
0.03
2.6
2.8
5.3
4.3
e9/l
0.73
21
210
26
269
0.96
0.02
3.3
4.3
72.3
89.1
ng/l
0.90
20
244
108
1091
0.99
0.02
1.6
1.6
1.5
1.4
mmol/l
0.34
91
920
14
133
1.05
0.01
1.6
1.3
—
—
—
0
0
15
155
0.97
0.00
1.3
1.2
—
—
—
0
0
21
206
1.02
0.00
1.1
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
2.6
—
0
9
0
6
0.00
0.00
0.0
5.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
2.0
—
0
7
5
59
0.85
0.00
1.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
90.3
—
0
7
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
57
0.88
0.00
1.0
1.5
—
—
—
0
0
7
71
0.99
0.00
1.1
1.1
—
—
—
0
0
5
57
0.88
0.00
1.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
195.4
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
7
69
1.01
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
183.3
—
0
7
0
8
0.00
0.00
0.0
5.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
7
72
0.97
0.00
1.1
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_BURSITISKNEEOTH and mortality.

Females

Parameter HR [95% CI] p-value
M13_BURSITISKNEEOTH 1.189 [0.9, 1.56] 0.215
Birth year 0.992 [0.98, 1.0] 0.077

During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 858 females with M13_BURSITISKNEEOTH died.

Males

Parameter HR [95% CI] p-value
M13_BURSITISKNEEOTH 1.013 [0.83, 1.24] 0.9
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 145 out of 1693 males with M13_BURSITISKNEEOTH died.

Mortality risk

Mortality risk for people of age

years, who have M13_BURSITISKNEEOTH.

N-year risk Females Males
1 0.081% 0.2%
5 0.569% 1.203%
10 1.57% 2.944%
15 2.927% 5.658%
20 5.204% 9.468%

Relationships between endpoints

Index endpoint: M13_BURSITISKNEEOTH – Other bursitis of knee

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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