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Tic disorders

F5_TIC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F95
  • Hospital discharge: ICD-9 3333A
  • Hospital discharge: ICD-8 30620
  • Cause of death: ICD-10 F95
  • Cause of death: ICD-9 3333A
  • Cause of death: ICD-8 30620

2 out of 7 registries used, show all original rules.

497

4. Check minimum number of events

None

497

5. Include endpoints

None

497

6. Filter based on genotype QC (FinnGen only)

497

Control definitions (FinnGen only)

Control exclude
F5_BEHEMOCHILD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F90-F98
Name in latin
Perturbationes ticiformes

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 497 251 246
Unadjusted period prevalence (%) 0.10 0.09 0.11
Median age at first event (years) 14.86 17.47 12.20

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
431
Matched controls
4312
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F95.9
ICD-10 Finland
Tic disorder, unspecified
+∞
172.9
154
*
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
2218.0
162.2
147
*
F95.0
ICD-10 Finland
Transient tic disorder
1261.0
104.8
98
*
F95.1
ICD-10 Finland
Chronic motor or vocal tic disorder
+∞
80.8
75
*
N05AX08
ATC
risperidone; systemic
12.4
61.4
118
127
F90.0
ICD-10 Finland
Disturbance of activity and attention
16.1
47.5
79
59
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
6.1
45.8
146
336
N06BA04
ATC
methylphenidate; oral
17.7
40.3
64
42
N05AX12
ATC
aripiprazole; systemic
8.7
35.2
80
110
N05AD01
ATC
haloperidol; systemic
23.4
34.9
50
24
N05AH04
ATC
quetiapine; oral
4.4
30.5
129
382
N03AE01
ATC
clonazepam; systemic
12.4
30.0
55
50
30620
ICD-8 Finland
Special symptoms not elsewhere classified, Tics
+∞
27.4
26
*
F95.8
ICD-10 Finland
Other tic disorders
+∞
25.2
24
*
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
7.1
24.8
63
101
F93.89
ICD-10 Finland
Other childhood emotional disorders
92.0
23.9
26
*
N06AB06
ATC
sertraline; oral
4.4
23.2
92
249
N05BA04
ATC
oxazepam; oral
3.6
22.4
119
417
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.8
20.8
100
321
N06AB03
ATC
fluoxetine; oral
4.4
20.2
78
204
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
37.8
20.0
25
7
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
8.9
20.0
43
53
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
6.9
20.0
51
82
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
9.9
19.3
39
43
N06BA09
ATC
atomoxetine; oral
+∞
18.9
18
*
IGY99
NOMESCO Finland
Other psychiatric treatment contact
7.3
18.4
45
68
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
38.5
17.8
22
6
IGP01
NOMESCO Finland
Psychiatric family contact
11.1
17.5
33
32
N05AH03
ATC
olanzapine; systemic
5.1
17.4
57
125
F42.2
ICD-10 Finland
Mixed obsessional thoughts and acts
12.3
16.3
29
25
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
5.3
16.2
51
107
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.5
16.0
59
147
F84.5
ICD-10 Finland
Asperger syndrome
14.5
15.7
26
19
N06AX16
ATC
venlafaxine; oral
3.6
15.7
77
248
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.2
15.5
90
329
F42.9
ICD-10 Finland
Obsessive-compulsive disorder, unspecified
16.9
15.4
24
15
N03AX09
ATC
lamotrigine; oral
5.6
15.0
44
85
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
6.7
14.9
38
61
IGV01
NOMESCO Finland
Psychiatric network contact
11.0
14.9
28
27
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
+∞
14.7
14
*
N05BA01
ATC
diazepam; systemic, rectal
3.7
14.0
63
188
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
+∞
13.6
13
*
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
7.3
13.4
32
47
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.2
12.9
71
247
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
8.4
12.5
27
34
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.5
12.5
61
195
N03AG01
ATC
valproic acid; systemic, rectal
4.5
12.5
44
105
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
66.8
11.7
13
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.8
11.6
49
139
N05AG02
ATC
pimozide; oral
+∞
11.5
11
*
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
+∞
11.5
11
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.2
11.2
42
107
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
7.6
10.6
24
33
G24.5
ICD-10 Finland
Blepharospasm
112.6
10.5
11
*
F98.9
ICD-10 Finland
Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
+∞
10.5
10
*
F42.1
ICD-10 Finland
Predominantly compulsive acts [obsessional rituals]
12.5
10.4
18
15
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.8
10.4
73
295
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
5.3
10.4
31
62
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
33.4
10.4
13
*
N06AB10
ATC
escitalopram; oral
2.3
10.4
105
522
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.4
10.1
36
87
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
5.5
10.0
29
56
N06AX11
ATC
mirtazapine; oral
2.2
9.9
110
570
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
6.4
9.8
25
41
N06AB04
ATC
citalopram; systemic
2.7
9.7
70
289
N06AX12
ATC
bupropion; oral
3.3
9.6
48
156
IEV99
NOMESCO Finland
Other psychiatric network intervention
10.4
9.6
18
18
G51.3
ICD-10 Finland
Clonic hemifacial spasm
102.1
9.4
10
*
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
5.6
9.2
26
49
IGY02
NOMESCO Finland
Psychiatric monitoring contact
4.0
9.1
36
97
F83
ICD-10 Finland
Mixed specific developmental disorders
5.5
9.1
26
50
R42
ICD-10 Finland
Dizziness and giddiness
2.6
8.9
68
289
C07AA05
ATC
propranolol; systemic
2.3
8.9
85
409
F80.1
ICD-10 Finland
Expressive language disorder
6.8
8.8
21
32
RT420
NOMESCO Finland
NA
51.0
8.7
10
*
R25.3
ICD-10 Finland
Fasciculation
51.0
8.7
10
*
F42.0
ICD-10 Finland
Predominantly obsessional thoughts or ruminations
8.5
8.7
18
22
F88
ICD-10 Finland
Other disorders of psychological development
20.5
8.5
12
6
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
6.9
8.5
20
30
N03AF01
ATC
carbamazepine; oral, rectal
6.4
8.4
21
34
N03AX12
ATC
gabapentin; oral
3.1
8.4
47
165
SPAT1240
SPAT
Therapeutic discussion
2.3
8.4
80
384
F98.02
ICD-10 Finland
Non-organic nocturnal and diurnal enuresis
+∞
8.4
8
*
F91.9
ICD-10 Finland
Conduct disorder, unspecified
+∞
8.4
8
*
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
12.0
8.1
14
12
F84.8
ICD-10 Finland
Other pervasive developmental disorders
22.5
8.0
11
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
8.0
154
984
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.2
7.9
40
132
N06AA04
ATC
clomipramine; systemic
9.7
7.8
15
16
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.6
7.8
34
100
M79.6
ICD-10 Finland
Pain in limb
1.9
7.7
123
733
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
12.1
7.6
13
11
N04AA02
ATC
biperiden; systemic
9.1
7.6
15
17
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.6
7.6
33
97
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.4
7.5
26
62
N05BE01
ATC
buspirone; oral
7.9
7.4
16
21
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.3
7.4
26
63
SPAT1307
SPAT
Psychosocial counselling and guidance
2.4
7.3
66
306
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
6.4
7.3
18
29
F93.80
ICD-10 Finland
Generalized anxiety in the bardom age
+∞
7.3
7
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
7.3
85
445
F31.8
ICD-10 Finland
Other bipolar affective disorders
7.5
7.2
16
22
SPAT1243
SPAT
Psychiatric/psychological examination
3.2
7.2
37
124
Z71.8
ICD-10 Finland
Other specified counselling
1.9
7.2
114
677
F84.0
ICD-10 Finland
Childhood autism
20.4
7.2
10
5
IEP99
NOMESCO Finland
Other psychiatric family intervention
9.0
7.1
14
16
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
6.5
7.0
17
27
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
6.9
96
541
M03BX01
ATC
baclofen; systemic
14.1
6.9
11
8
ICA03
NOMESCO Finland
Psychiatric treatment plan, outsourced psychotherapy
22.9
6.7
9
*
N05CF01
ATC
zopiclone; oral
2.1
6.7
75
385
F60.9
ICD-10 Finland
Personality disorder, unspecified
8.0
6.7
14
18
N06AB05
ATC
paroxetine; oral
3.7
6.6
27
76
Z72.8
ICD-10 Finland
Other problems related to lifestyle
10.2
6.6
12
12
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
6.5
78
412
C02AC01
ATC
clonidine; systemic
70.8
6.4
7
*
F95
ICD-10 Finland
Tic disorders
70.8
6.4
7
*
N06BA12
ATC
lisdexamfetamine; oral
14.6
6.4
10
7
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
6.3
81
442
J01DB01
ATC
cefalexin; oral
1.8
6.3
325
2736
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.2
6.3
22
54
F91.3
ICD-10 Finland
Oppositional defiant disorder
+∞
6.3
6
*
F90.1
ICD-10 Finland
Hyperkinetic conduct disorder
+∞
6.3
6
*
F94.9
ICD-10 Finland
Childhood disorder of social functioning, unspecified
+∞
6.3
6
*
F41.8
ICD-10 Finland
Other specified anxiety disorders
3.4
6.2
28
86
F50.9
ICD-10 Finland
Eating disorder, unspecified
5.9
6.2
16
28
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.7
6.1
41
164
Z63.8
ICD-10 Finland
Other specified problems related to primary support group
12.8
6.1
10
8
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
6.0
43
178
R03AC02
ATC
salbutamol; inhalant
1.6
6.0
214
1614

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
74
182
4.60
28.31
2.6
2.7
—
—
—
0
0
171
871
2.47
18.95
2.7
3.1
2.4
2.4
mmol/l
0.31
150
780
381
2803
2.54
17.42
4.1
3.6
14.5
14.5
pmol/l
0.14
350
2530
221
1355
2.14
14.98
2.6
2.6
68.3
70.2
nmol/l
0.46
213
1256
166
937
2.16
13.69
1.9
1.6
101.2
99.4
pmol/l
0.21
92
473
275
1872
2.05
13.67
3.2
2.7
—
—
—
0
0
412
3305
2.44
12.94
5.1
4.1
1.9
1.9
mu/l
0.19
393
3085
321
2349
2.04
12.60
7.1
6.3
86.6
84.6
u/l
0.25
304
2201
380
2967
2.19
12.42
3.8
2.9
5.6
5.6
mmol/l
0.31
359
2725
132
714
2.16
11.91
2.9
2.1
169.3
361.2
u/l
1.10
124
674
92
428
2.41
11.88
1.5
1.6
426.9
17632024.1
pmol/l
0.50
79
380
426
3512
2.49
11.83
14.4
10.8
139.6
139.5
mmol/l
0.06
421
3384
105
520
2.29
11.75
1.6
1.3
18.3
20.4
nmol/l
0.99
94
453
76
325
2.58
11.73
3.4
2.6
—
—
—
0
0
426
3523
2.46
11.55
14.5
10.7
3.9
3.9
mmol/l
0.09
420
3383
332
2500
1.99
11.50
4.3
3.7
8.6
8.2
mm/h
0.25
306
2309
287
2062
1.93
11.39
7.4
7.9
0.2
0.2
e9/l
0.16
251
1832
218
1443
1.91
10.99
8.1
7.6
1.2
1.2
mmol/l
0.14
188
1248
216
1435
1.89
10.69
6.1
5.9
10.0
11.0
umol/l
1.29
206
1346
148
868
2.00
10.59
3.7
3.8
9.0
8.8
mmol/l
0.14
129
776
277
2005
1.86
10.35
6.9
7.4
0.6
0.6
e9/l
0.06
238
1741
277
2006
1.86
10.32
7.0
7.4
0.0
0.0
e9/l
0.04
238
1743
81
383
2.33
10.00
2.4
2.0
—
—
—
0
0
286
2113
1.83
9.78
6.9
7.3
2.0
2.0
e9/l
0.17
250
1876
74
343
2.36
9.55
1.6
1.7
1163.3
1150.6
nmol/l
0.04
61
266
177
1141
1.86
9.34
5.0
6.0
38.0
37.7
g/l
0.29
166
1073
89
450
2.19
9.34
6.2
6.5
0.8
0.8
mmol/l
0.81
82
427
262
1926
1.76
8.73
7.2
7.6
8.5
8.3
%
0.81
250
1838
90
470
2.12
8.67
2.4
1.9
—
—
—
0
0
273
2035
1.76
8.63
7.0
7.3
32.0
31.8
%
0.08
259
1944
201
1379
1.77
8.44
6.3
7.5
—
—
—
0
0
252
1848
1.74
8.34
7.3
7.6
0.7
0.7
%
0.06
239
1755
258
1910
1.73
8.20
7.1
7.5
3.0
2.9
%
0.06
242
1813
143
896
1.84
8.08
2.8
2.5
52.4
57.4
u/l
0.54
133
831
93
507
2.03
7.95
2.4
1.9
—
—
—
0
0
194
1338
1.74
7.87
7.1
7.5
1.2
1.2
mmol/l
0.03
179
1241
93
512
2.00
7.73
2.4
1.9
—
—
—
0
0
124
753
1.86
7.70
2.7
3.3
1.0
1.0
kg/l
—
8
101
265
1999
1.70
7.68
7.0
7.2
52.9
53.9
%
0.70
254
1911
93
514
2.00
7.64
2.4
1.9
—
—
—
0
0
293
2274
1.70
7.61
10.4
9.5
3.7
3.9
e9/l
0.68
257
1974
20
49
4.21
7.60
1.5
2.5
—
—
—
0
0
91
508
1.97
7.25
2.0
1.8
—
—
—
0
0
24
76
3.27
6.37
1.1
1.1
—
—
—
0
0
106
656
1.78
6.06
5.1
4.3
—
—
—
0
0
99
602
1.80
6.00
3.5
2.8
—
—
—
0
0
440
3943
2.01
5.89
10.6
8.0
27.7
27.6
u/l
0.05
431
3805
11
20
5.60
5.83
1.3
2.6
11.0
17.1
umol/l
1.05
11
20
241
1862
1.57
5.73
10.2
9.5
0.0
0.0
e9/l
0.28
193
1483
127
841
1.69
5.68
3.7
2.9
32.7
39.7
ng/l
0.15
65
396
233
1790
1.57
5.66
3.1
2.9
78.0
73.4
ug/l
0.22
219
1683
293
2384
1.56
5.42
4.2
3.8
—
—
—
0
0
28
108
2.69
5.32
2.0
1.3
—
—
—
0
0
21
69
3.13
5.28
1.1
1.1
—
—
—
0
0
123
831
1.64
5.03
3.0
2.7
2.7
2.7
mg/l
0.09
108
703
43
208
2.17
5.01
6.7
3.8
—
—
—
0
0
363
3129
1.59
4.99
3.5
3.1
4.5
4.6
mmol/l
1.21
349
2957
102
658
1.69
4.98
2.5
2.7
562.5
597.4
mosm/kgh2o
0.58
83
569
58
315
1.95
4.97
1.8
3.3
10.5
10.0
g/l
0.70
52
292
144
1016
1.59
4.92
3.3
3.4
31.1
103.0
e6/l
0.55
112
774
116
777
1.64
4.90
3.9
3.9
7.4
7.4
ph
1.30
21
148
146
1039
1.57
4.79
8.4
8.2
—
—
—
0
0
239
1897
1.50
4.72
4.5
4.9
6.2
6.4
mmol/l
0.64
218
1716
362
3139
1.56
4.65
3.7
3.3
2.7
2.8
mmol/l
0.52
345
2941
358
3106
1.55
4.49
3.4
3.1
1.4
1.4
mmol/l
0.85
340
2930
310
2613
1.50
4.44
4.3
3.9
37.0
37.5
mmol/mol
0.37
296
2477
212
1675
1.46
4.11
4.6
4.5
0.0
0.0
estimate
0.00
47
344
12
32
3.82
4.11
1.0
1.3
—
—
—
0
0
164
1235
1.49
4.04
4.0
3.9
19.3
60.7
e6/l
1.76
119
821
130
933
1.53
4.03
3.2
3.2
—
—
—
0
0
66
400
1.75
4.01
3.0
2.8
2.4
2.4
mmol/l
0.13
59
346
129
927
1.53
3.97
3.4
3.3
0.3
0.2
e6/l
0.33
97
695
41
214
2.00
3.95
2.9
4.2
80.7
66.7
e9/l
0.67
29
138
37
186
2.07
3.94
1.9
3.5
—
—
—
0
0
55
318
1.82
3.91
2.1
2.5
188.6
32.2
u/l
0.47
47
263
212
1694
1.44
3.79
3.5
3.2
0.0
0.0
estimate
0.00
45
328
427
3908
1.66
3.77
14.2
10.2
18.9
22.0
mg/l
1.57
319
2821
72
458
1.67
3.68
1.3
1.2
—
—
—
0
0
167
1284
1.45
3.64
1.5
1.5
0.6
1.6
u/ml
1.89
38
290
17
62
2.80
3.62
1.9
3.1
—
—
—
0
0
9
17
5.37
3.52
3.2
7.4
16.7
19.6
ug/l
—
9
17
6
6
10.10
3.50
2.0
4.2
—
—
—
0
0
477
4534
2.29
3.44
20.6
14.5
29.6
29.7
pg
0.89
471
4478
119
865
1.49
3.43
3.1
3.4
0.0
0.0
estimate
0.50
45
334
477
4535
2.29
3.42
20.6
14.5
88.3
88.4
fl
0.21
471
4480
477
4535
2.29
3.42
20.6
14.6
4.7
4.7
e12/l
0.09
460
4385
477
4537
2.28
3.38
20.7
14.6
6.7
6.6
e9/l
0.15
460
4384
150
1145
1.44
3.36
1.5
1.6
1.9
2.0
g/l
0.21
86
668
207
1674
1.41
3.36
3.4
3.2
0.0
0.0
estimate
0.00
45
331
338
2974
1.43
3.34
3.3
2.9
1.2
1.2
mmol/l
0.02
322
2806
476
4526
2.22
3.34
20.7
14.6
259.5
258.1
e9/l
0.19
462
4381
477
4540
2.26
3.32
20.8
14.7
137.5
137.8
g/l
0.19
471
4484
125
929
1.46
3.20
4.7
5.4
1.1
1.1
inr
0.22
47
303
72
479
1.59
3.09
7.4
7.8
1.1
1.2
mmol/l
0.68
67
452
65
423
1.62
3.05
2.1
1.6
—
—
—
0
0
98
701
1.50
3.03
2.4
2.8
11.1
5.8
e6/l
1.57
81
615
25
122
2.10
2.92
2.2
2.3
—
—
—
0
0
30
534
0.53
2.88
1.3
1.2
—
—
—
0
0
48
293
1.71
2.88
1.3
1.4
235.6
350.8
u/ml
0.53
43
270
7
13
5.44
2.88
1.7
1.1
—
—
—
0
0
59
384
1.61
2.78
4.2
4.0
9.0
7.1
umol/l
0.17
50
319
101
745
1.45
2.67
1.7
1.6
1.5
1.4
mmol/l
0.65
87
662
388
3560
1.41
2.57
17.4
12.8
13.2
13.2
%
0.20
382
3496
434
4067
1.53
2.57
12.3
8.4
—
—
—
0
0
103
770
1.43
2.53
2.9
3.2
—
—
—
0
0
32
182
1.81
2.46
1.5
1.3
—
—
—
0
0
71
497
1.50
2.44
1.3
1.2
18.8
26.9
iu/ml
0.41
17
151
35
206
1.75
2.41
5.8
15.0
1.1
1.2
inr
—
8
43
139
1102
1.36
2.41
1.8
1.8
—
—
—
0
0
117
903
1.39
2.39
4.8
4.6
—
—
—
0
0
51
333
1.59
2.39
6.0
6.2
5.2
5.1
kpa
0.73
45
313
69
483
1.50
2.37
1.5
1.4
301.8
506.5
titre
1.30
11
89
52
345
1.57
2.28
1.2
1.3
—
—
—
0
0
11
42
2.66
2.20
1.2
1.3
—
—
—
0
0
18
88
2.08
2.14
1.2
2.8
—
—
—
0
0
57
393
1.51
2.12
6.9
9.0
—
—
—
0
0
9
31
2.94
2.08
1.7
1.6
—
—
—
0
0
71
514
1.44
2.08
3.4
3.7
926.6
94.6
mg/l
0.47
49
359
7
20
3.53
2.06
8.4
6.0
—
—
—
0
0
7
20
3.53
2.06
1.0
2.0
—
—
—
0
0
50
339
1.53
2.01
1.2
1.2
135.9
126.5
iu/ml
0.07
16
115
61
432
1.47
2.00
4.4
7.1
2.0
1.6
mmol/l
0.59
50
340
36
228
1.62
1.94
1.1
1.2
—
—
—
0
0
31
190
1.67
1.89
3.8
4.5
1.2
1.2
mmol/l
0.56
25
169
7
22
3.21
1.88
1.1
1.2
—
—
—
0
0
11
46
2.42
1.86
1.6
8.1
—
—
—
0
0
72
534
1.41
1.86
4.2
4.6
12.1
14.6
mg/mmol
0.14
49
379
32
200
1.64
1.82
1.7
1.4
—
—
—
0
0
92
714
1.35
1.81
3.1
2.7
1.1
1.0
mg/l
0.10
57
496
8
29
2.79
1.80
1.1
1.0
266.9
301.5
mg/l
—
8
23
12
54
2.25
1.75
1.3
3.9
1.1
1.3
e9/l
—
5
32
6
18
3.36
1.75
1.2
1.3
—
—
—
0
0
172
1461
1.27
1.75
2.8
2.2
—
—
—
0
0
38
254
1.54
1.66
1.5
1.3
199.1
271.5
miu/ml
0.55
12
132
75
963
0.74
1.63
1.6
1.6
—
—
—
0
0
13
63
2.09
1.61
3.0
5.8
3.9
2.5
mmol/l
—
7
32
51
366
1.44
1.59
3.8
2.6
2866.4
5334.0
u/l
0.47
17
151
7
26
2.72
1.58
1.7
2.0
32.6
32.5
pg
—
7
26
43
299
1.48
1.57
1.6
1.4
—
—
—
0
0
420
3991
1.34
1.56
14.6
11.2
40.6
40.8
%
0.17
336
3427
14
71
2.00
1.55
1.6
1.5
289.6
311.3
ug/g
—
5
43
0
42
0.00
1.53
0.0
4.5
—
—
—
0
0
5
15
3.36
1.52
1.0
1.1
—
—
—
0
0
7
27
2.61
1.52
1.3
1.2
—
—
—
0
0
53
387
1.41
1.51
2.7
2.1
—
—
—
0
0
65
492
1.37
1.51
3.2
2.9
76.3
910.3
ng/l
2.06
29
281
18
101
1.81
1.51
1.2
3.0
—
—
—
0
0
20
118
1.72
1.43
1.8
1.6
—
—
—
0
0
27
174
1.58
1.40
1.3
1.6
331.4
170.3
u/ml
1.12
13
101
11
53
2.10
1.39
1.2
3.3
—
—
—
0
0
90
727
1.29
1.35
3.3
3.1
146.0
127.8
ug/g
0.20
70
575
36
250
1.47
1.35
8.1
4.7
1.0
0.7
%
0.42
13
67
30
201
1.52
1.33
1.4
1.5
—
—
—
0
0
31
210
1.51
1.31
1.1
1.2
4.0
1.8
u/ml
0.47
19
122
31
210
1.51
1.31
1.1
1.2
—
—
—
0
0
100
823
1.27
1.30
2.9
2.4
—
—
—
0
0
62
478
1.34
1.30
1.3
1.2
11.4
6.9
u/ml
0.23
24
196
8
34
2.37
1.29
1.1
1.1
—
—
—
0
0
9
45
2.02
1.24
2.1
5.0
8.0
13.5
%
—
9
45
14
78
1.82
1.22
1.6
1.5
—
—
—
0
0
8
37
2.18
1.22
1.8
4.9
—
—
—
0
0
25
165
1.54
1.20
3.8
2.2
—
—
—
0
0
34
240
1.45
1.19
8.4
4.7
0.3
0.1
%
0.74
11
62
28
190
1.50
1.19
1.1
1.2
3.2
7.7
u/ml
1.86
20
140
18
110
1.66
1.17
11.4
13.2
—
—
—
0
0
33
233
1.45
1.16
7.5
4.3
0.8
0.3
%
—
9
49
8
40
2.02
1.12
1.1
4.5
33.3
27.7
%
—
8
40
18
112
1.63
1.10
1.1
1.1
1.6
7.9
u/ml
2.56
11
62
8
41
1.97
1.09
1.0
1.1
—
—
—
0
0
87
721
1.25
1.08
2.0
1.6
—
—
—
0
0
20
130
1.56
1.04
1.1
1.1
2.5
9.1
u/ml
1.89
11
65
7
34
2.07
1.03
1.7
5.0
—
—
—
0
0
26
182
1.45
0.98
1.2
1.1
0.3
5.1
u/ml
—
10
60
41
312
1.34
0.97
7.0
7.5
105.4
104.2
mmol/l
0.94
41
307
21
142
1.50
0.94
1.5
1.7
—
—
—
0
0
6
27
2.24
0.93
1.3
1.2
338.0
168.6
iu/ml
—
6
27
37
279
1.35
0.93
7.6
6.4
—
—
—
0
0
6
28
2.16
0.92
4.3
1.7
—
—
—
0
0
112
972
1.20
0.90
3.2
2.7
—
—
—
0
0
33
246
1.37
0.90
1.7
1.9
10.1
13.5
iu/l
0.55
24
182
6
29
2.08
0.89
1.5
1.2
—
—
—
0
0
26
186
1.42
0.89
1.1
1.2
0.8
1.4
u/ml
0.39
17
121
20
137
1.48
0.85
3.0
3.2
0.1
0.1
e6/l
0.04
20
130
10
57
1.77
0.84
2.1
1.7
—
—
—
0
0
31
233
1.35
0.81
9.1
4.8
0.0
0.1
%
—
8
55
6
33
1.83
0.79
1.0
1.3
—
—
nmol/l
—
0
0
14
90
1.57
0.79
12.1
11.2
—
—
—
0
0
20
140
1.45
0.78
1.1
1.1
—
—
—
0
0
0
27
0.00
0.77
0.0
3.0
—
17.7
—
0
27
0
27
0.00
0.77
0.0
2.5
—
2.6
—
0
27
16
107
1.51
0.77
2.9
3.3
—
—
—
0
0
48
388
1.26
0.76
1.6
1.4
—
—
—
0
0
25
334
0.74
0.76
1.1
1.3
—
—
—
0
0
20
141
1.44
0.75
3.7
4.4
7.4
6.1
ug/l
0.09
15
110
10
60
1.68
0.72
1.2
7.8
—
—
—
0
0
12
76
1.59
0.72
1.8
1.6
—
—
—
0
0
14
205
0.67
0.71
1.9
1.4
—
—
—
0
0
5
26
1.93
0.71
1.4
1.2
—
—
—
0
0
5
26
1.93
0.71
2.2
1.3
—
—
—
0
0
9
59
1.53
0.68
1.2
1.2
—
—
—
0
0
7
42
1.68
0.68
2.0
1.7
286.7
290.4
mosm/kgh2o
—
7
28
21
153
1.39
0.68
3.7
3.1
64.9
125.1
ng/l
1.61
14
134
16
112
1.44
0.64
1.2
1.2
—
—
—
0
0
5
29
1.73
0.64
1.4
1.2
—
—
—
0
0
45
371
1.23
0.63
1.4
1.4
—
—
—
0
0
16
113
1.43
0.62
1.1
1.2
—
—
—
0
0
19
139
1.38
0.61
1.0
1.2
—
—
—
0
0
19
139
1.38
0.61
1.3
1.3
—
—
—
0
0
15
105
1.44
0.60
5.7
2.9
—
—
—
0
0
26
201
1.31
0.60
8.4
13.8
1.1
1.1
mg/l
0.17
26
193
14
97
1.46
0.59
2.7
2.0
3.0
7.4
iu/l
—
6
33
10
64
1.57
0.59
1.0
4.2
—
—
—
0
0
6
36
1.67
0.57
1.5
1.1
—
—
—
0
0
6
37
1.63
0.55
1.0
1.3
—
—
—
0
0
6
37
1.63
0.55
1.8
1.1
—
—
—
0
0
15
108
1.40
0.53
1.5
1.5
—
63.8
—
0
13
15
108
1.40
0.53
1.1
1.1
—
—
—
0
0
118
1293
0.89
0.53
1.6
1.7
—
—
—
0
0
120
1096
1.13
0.51
2.0
1.7
—
—
—
0
0
114
1245
0.89
0.49
2.1
2.1
—
—
—
0
0
7
50
1.41
0.45
1.0
1.3
—
—
—
0
0
40
340
1.19
0.44
1.8
1.9
—
—
—
0
0
37
313
1.20
0.43
3.4
3.4
—
—
—
0
0
11
78
1.42
0.43
1.4
1.7
—
—
—
0
0
5
31
1.62
0.43
1.4
3.4
2.9
2.1
mmol/l
—
5
31
8
57
1.41
0.42
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
9
66
1.37
0.38
2.4
2.4
—
—
—
0
0
5
36
1.39
0.38
1.0
1.2
26.8
18.0
u/l
—
5
31
6
43
1.40
0.35
2.3
4.1
—
—
—
0
0
6
43
1.40
0.35
2.3
2.4
—
—
—
0
0
40
349
1.16
0.35
2.2
1.5
—
—
—
0
0
6
87
0.69
0.33
2.7
2.9
26.0
31.4
mu/l
—
6
81
14
112
1.26
0.28
1.0
1.0
0.1
0.8
u/ml
—
5
44
27
233
1.17
0.28
9.0
9.6
0.6
0.8
mmol/l
0.16
21
180
22
187
1.18
0.27
10.0
10.9
123.0
125.2
g/l
0.21
22
179
8
67
1.20
0.26
1.3
1.2
—
—
—
0
0
107
1010
1.08
0.25
2.7
2.4
—
—
—
0
0
16
133
1.21
0.24
1.9
1.6
—
—
—
0
0
5
38
1.32
0.23
1.0
1.2
—
—
—
0
0
5
40
1.25
0.22
1.0
1.4
—
—
—
0
0
20
172
1.17
0.22
1.6
1.4
—
—
—
0
0
13
107
1.22
0.22
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
1.1
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
9.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
5.9
—
16.0
—
0
7
6
49
1.23
0.20
10.3
3.8
—
—
—
0
0
49
454
1.09
0.19
1.6
1.5
—
—
—
0
0
38
350
1.09
0.17
2.5
2.3
15.3
13.4
nmol/l
0.40
32
314
8
68
1.18
0.16
2.1
1.8
1.4
5.6
ug/l
—
8
60
20
178
1.13
0.15
1.6
1.5
—
—
—
0
0
28
259
1.09
0.12
1.7
2.0
5.4
6.3
u/l
0.46
22
189
19
172
1.11
0.11
1.6
1.4
—
—
—
0
0
12
105
1.15
0.11
1.6
1.5
—
—
—
0
0
11
96
1.15
0.10
2.5
5.4
—
—
—
0
0
16
145
1.11
0.09
5.4
6.8
0.5
0.3
g/l
—
9
88
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
5
48
1.04
0.09
1.0
1.0
—
—
—
0
0
6
71
0.84
0.07
1.2
1.1
—
—
—
0
0
10
89
1.13
0.07
1.3
1.1
—
—
—
0
0
24
227
1.06
0.06
1.8
2.1
3.4
3.9
e9/l
0.53
19
201
12
110
1.09
0.05
1.2
1.2
—
—
—
0
0
33
320
1.03
0.03
1.2
1.2
—
—
—
0
0
26
269
0.96
0.02
3.4
2.3
0.7
0.7
ug/l
0.01
14
134
16
168
0.95
0.02
1.2
1.2
—
—
—
0
0
11
117
0.94
0.01
4.3
7.8
—
—
—
0
0
23
223
1.03
0.01
1.1
1.1
—
—
—
0
0
96
968
0.99
0.01
2.2
1.9
—
—
—
0
0
11
111
0.99
0.00
5.2
4.3
24.6
24.6
mmol/l
0.00
11
106
153
1526
1.00
0.00
4.3
3.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
0.00
0.0
5.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.6
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: F5_TIC – Tic disorders

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).