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Other and unspecified disorders of psychological development

EFO MESH Endpoint Browser PheWeb

F5_PSYCHDEVOTH

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F88, F89
  • Hospital discharge: ICD-9 — 3159
  • Cause of death: ICD-10 — F88, F89
  • Cause of death: ICD-9 — 3159

2 out of 7 registries used, show all original rules.

426

4. Check minimum number of events

None

426

5. Include endpoints

None

426

6. Filter based on genotype QC (FinnGen only)

426

Control definitions (FinnGen only)

Control exclude
F5_PSYCHDEV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11758 3380 8372
Only index persons 8924 2658 6266
Unadjusted period prevalence (%)
Whole population 0.19 0.10 0.23
Only index persons 0.20 0.10 0.24
Median age at first event (years)
Whole population 8.17 8.75 7.94
Only index persons 9.13 9.99 8.76

-FinnGen-

Key figures

All Female Male
Number of individuals 426 169 257
Unadjusted period prevalence (%) 0.09 0.06 0.11
Median age at first event (years) 9.20 11.37 7.78

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
374
Matched controls
3672
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F88
ICD-10 Finland
Other disorders of psychological development
1242.1
167.6
152
*
F89
ICD-10 Finland
Unspecified disorder of psychological development
+∞
164.1
146
*
3159X
ICD-9 Finland
Specific delays in development, Unspecified delay in development
+∞
109.2
100
*
F83
ICD-10 Finland
Mixed specific developmental disorders
+∞
57.4
54
*
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
11.4
50.4
101
115
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
10.9
42.9
87
99
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
13.2
39.0
71
64
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
+∞
39.0
37
*
N05AX08
ATC
risperidone; systemic
9.2
38.9
87
117
F84.5
ICD-10 Finland
Asperger syndrome
109.6
37.2
40
*
IGP01
NOMESCO Finland
Psychiatric family contact
13.3
36.1
65
57
F90.0
ICD-10 Finland
Disturbance of activity and attention
7.3
33.0
86
145
IGV01
NOMESCO Finland
Psychiatric network contact
16.1
32.8
54
38
IGY99
NOMESCO Finland
Other psychiatric treatment contact
8.8
32.4
73
98
F82
ICD-10 Finland
Specific developmental disorder of motor function
165.5
29.9
31
*
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
38.9
28.7
36
10
N05AX12
ATC
aripiprazole; systemic
7.7
28.4
70
107
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.3
28.1
123
373
IEP99
NOMESCO Finland
Other psychiatric family intervention
15.5
27.1
45
32
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
11.0
26.7
52
53
N05AH03
ATC
olanzapine; systemic
6.9
26.4
70
119
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
142.5
25.8
27
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
6.2
25.7
74
140
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
7.4
25.7
64
99
F84.8
ICD-10 Finland
Other pervasive developmental disorders
+∞
25.1
24
*
IEV99
NOMESCO Finland
Other psychiatric network intervention
15.6
24.3
40
28
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
+∞
23.0
22
*
F80.1
ICD-10 Finland
Expressive language disorder
125.6
22.7
24
*
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
47.4
22.5
27
6
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
8.0
22.2
52
73
F29
ICD-10 Finland
Unspecified nonorganic psychosis
6.4
21.7
60
107
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
8.1
21.5
50
69
F80.2
ICD-10 Finland
Receptive language disorder
+∞
20.9
20
*
N06BA04
ATC
methylphenidate; oral
6.2
20.7
58
105
XA800
NOMESCO Finland
Neuropsychological investigation
6.9
20.5
53
86
IEP03
NOMESCO Finland
Focused parental counselling
10.8
20.2
39
39
N03AG01
ATC
valproic acid; systemic, rectal
5.9
20.1
59
113
3153X
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[PUHEEN KEHITYKSEN ERITYISVAIKEUS]
+∞
19.8
19
*
R62.0
ICD-10 Finland
Delayed milestone
11.4
19.7
37
35
N05AH04
ATC
quetiapine; oral
3.5
18.9
104
366
IGY02
NOMESCO Finland
Psychiatric monitoring contact
5.7
18.0
54
106
F84.0
ICD-10 Finland
Childhood autism
+∞
17.7
17
*
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
11.4
17.6
33
31
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
12.7
17.5
31
26
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
51.7
17.0
20
*
F93.89
ICD-10 Finland
Other childhood emotional disorders
8.2
16.9
38
50
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
174.4
16.5
17
*
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
24.0
16.5
23
10
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
87.3
15.6
17
*
N03AX09
ATC
lamotrigine; oral
5.1
15.3
50
108
IEP02
NOMESCO Finland
Child-centred family therapy
8.2
14.8
33
43
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
5.9
14.1
40
73
R5599
NOMESCO Finland
Other rehabilitation service
8.8
14.1
30
36
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
7.7
13.9
32
44
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
+∞
13.5
13
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.3
13.2
50
126
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
6.1
13.2
36
63
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.5
13.0
64
204
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
5.7
12.9
37
69
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
5.6
12.1
35
66
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
9.6
11.5
23
25
F20.9
ICD-10 Finland
Schizophrenia, unspecified
9.2
11.3
23
26
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
9.9
11.3
22
23
F81.0
ICD-10 Finland
Specific reading disorder
35.6
11.2
14
*
R4120
NOMESCO Finland
Occupational therapy
4.4
10.3
37
89
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
33.0
10.3
13
*
RT420
NOMESCO Finland
NA
33.0
10.3
13
*
XA820
NOMESCO Finland
NA
23.7
10.2
14
6
RT150
NOMESCO Finland
NA
11.5
10.0
18
16
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.5
10.0
29
55
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
9.8
9.8
19
20
IBA02
NOMESCO Finland
Evaluation of need for psychiatric rehabilitation
7.0
9.6
23
34
F99
ICD-10 Finland
Mental disorder, not otherwise specified
7.3
9.5
22
31
ICC01
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric outpatient clinic
9.3
9.5
19
21
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
9.5
78
343
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.0
9.4
57
209
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
9.2
77
341
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
15.8
9.0
14
9
F91.3
ICD-10 Finland
Oppositional defiant disorder
37.0
9.0
11
*
N05AA02
ATC
levomepromazine; systemic
6.7
9.0
22
34
RS140
NOMESCO Finland
NA
18.8
8.9
13
7
183
Kela drug reimbursment
Lamotrigin and topiramate
8.8
8.8
18
21
P99
ICPC
Psychological disorders other
5.2
8.7
26
52
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
6.3
8.6
22
36
R1260
NOMESCO Finland
Evaluation of communicative skills
16.5
8.5
13
8
N05AB03
ATC
perphenazine; systemic, rectal
6.6
8.5
21
33
N05BA01
ATC
diazepam; systemic, rectal
3.2
8.5
44
146
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.9
8.5
55
209
N05BA06
ATC
lorazepam; systemic, sublingual
6.1
8.5
22
37
F90.1
ICD-10 Finland
Hyperkinetic conduct disorder
90.4
8.4
9
*
F81.1
ICD-10 Finland
Specific spelling disorder
+∞
8.3
8
*
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
+∞
8.3
8
*
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
8.7
8.3
17
20
RL140
NOMESCO Finland
NA
10.9
8.3
15
14
N05AH02
ATC
clozapine; systemic
5.3
8.2
24
47
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
33.5
8.0
10
*
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
17.3
8.0
12
7
N03AF01
ATC
carbamazepine; oral, rectal
7.4
7.9
18
25
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
3.5
7.9
36
108
N05BA09
ATC
clobazam; oral
6.7
7.9
19
29
N03AF02
ATC
oxcarbazepine; oral
4.3
7.6
27
65
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
6.3
7.5
19
31
P29
ICPC
Psychological sympt/compl other
2.9
7.4
44
160
F94.8
ICD-10 Finland
Other childhood disorders of social functioning
80.2
7.4
8
*
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
80.2
7.4
8
*
EBA15
NOMESCO Finland
Extraction of large number of teeth
5.0
7.3
22
45
RT160
NOMESCO Finland
NA
9.5
7.3
14
15
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.5
7.2
32
95
IEP01
NOMESCO Finland
Psychoeducation, family
7.4
7.2
16
22
S29
ICPC
Skin symptom/complaint other
2.4
7.2
65
301
A29
ICPC
General symptom/complaint other
2.9
7.1
44
163
N05AD01
ATC
haloperidol; systemic
8.0
7.1
15
19
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.3
7.1
66
307
N06AB04
ATC
citalopram; systemic
2.5
7.1
54
228
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
7.0
37
125
F98.9
ICD-10 Finland
Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
13.9
6.9
11
8
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
13.9
6.9
11
8
RL130
NOMESCO Finland
NA
8.4
6.8
14
17
IAB03
NOMESCO Finland
Neuropsychiatric consultation
40.1
6.7
8
*
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
40.1
6.7
8
*
F90.8
ICD-10 Finland
Other hyperkinetic disorders
40.1
6.7
8
*
3141A
ICD-9 Finland
Hyperkinetic syndrome of childhood, Hyperkinesis with developmental delay
40.1
6.7
8
*
R4170
NOMESCO Finland
Therapy forms involving educational rehabilitation
40.1
6.7
8
*
RT120
NOMESCO Finland
NA
16.8
6.7
10
6
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
6.7
66
315
P22
ICPC
Child behaviour symptom/complaint
3.5
6.7
30
90
IAZ99
NOMESCO Finland
Other psychiatric consultation
22.6
6.6
9
*
N06AB03
ATC
fluoxetine; oral
2.7
6.6
45
176
Z50.5
ICD-10 Finland
Speech therapy
3.7
6.6
27
75
N05AF03
ATC
chlorprothixene; systemic
5.6
6.6
18
33
R4110
NOMESCO Finland
Physiotherapy
2.0
6.5
90
499
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.8
6.4
17
30
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
69.7
6.4
7
*
A28
ICPC
Limited function/disability NOS
3.2
6.4
32
105
N04AA02
ATC
biperiden; systemic
8.2
6.3
13
16
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.9
6.3
37
135
RT130
NOMESCO Finland
NA
18.1
6.2
9
5
IEY21
NOMESCO Finland
Other intensified psychiatric treatment
18.1
6.2
9
5
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
6.2
31
101
V628A
ICD-9 Finland
Other psychosocial circumstances, Other psychological or physical stress, not elsewhere classified
+∞
6.2
6
*
3140B
ICD-9 Finland
Hyperkinetic syndrome of childhood, Attention deficit disorder
+∞
6.2
6
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.2
63
306
IAB01
NOMESCO Finland
Psychiatric pharmacotherapy consultation
26.7
6.2
8
*
F98.0
ICD-10 Finland
Nonorganic enuresis
26.7
6.2
8
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.6
6.1
20
45
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.7
6.1
40
155
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.9
6.0
35
126

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
226
1377
2.31
15.89
3.2
2.3
—
—
—
0
0
367
2897
2.77
12.46
12.5
10.4
139.5
139.4
mmol/l
0.19
361
2798
367
2900
2.76
12.38
12.3
10.4
3.9
3.9
mmol/l
0.84
361
2785
171
1008
2.11
12.17
7.9
9.0
—
—
—
0
0
311
2301
2.22
11.94
4.6
3.4
14.4
14.5
pmol/l
0.22
295
2135
199
1295
1.96
10.32
6.0
9.6
1.2
1.2
mmol/l
0.07
184
1177
20
37
5.53
10.25
28.6
27.5
1431.7
1445.4
nmol/l
0.02
20
37
338
2674
2.17
9.64
5.4
3.8
1.9
1.8
mu/l
0.93
325
2513
294
2216
1.98
9.53
4.1
2.5
5.9
5.5
mmol/l
2.53
280
2036
252
1843
1.84
8.51
5.9
5.8
101.4
102.2
u/l
0.06
242
1740
11
13
8.51
8.32
1.6
2.6
22.6
17.4
umol/l
0.40
11
13
267
2011
1.82
7.95
12.4
10.5
3.7
3.7
e9/l
0.18
227
1693
74
367
2.19
7.84
1.5
1.3
18.4
18.8
nmol/l
0.12
68
328
117
692
1.91
7.64
2.1
2.9
2.4
2.4
mmol/l
0.24
111
636
49
205
2.52
7.63
3.6
3.6
—
—
—
0
0
218
1559
1.77
7.62
4.9
6.0
6.2
6.3
mmol/l
0.06
208
1413
99
572
1.91
6.86
3.5
4.4
7.4
7.4
ph
0.21
17
101
187
1324
1.69
6.44
5.7
8.8
—
—
—
0
0
139
910
1.74
6.36
4.1
7.5
37.1
38.0
g/l
0.97
133
874
118
745
1.77
6.08
3.8
4.8
7.9
8.7
mmol/l
0.81
110
692
55
268
2.17
6.06
1.3
1.8
—
—
—
0
0
45
202
2.33
6.02
1.5
1.5
883.5
1088.6
nmol/l
0.78
38
159
238
1822
1.64
5.88
7.6
8.7
0.0
0.0
e9/l
0.24
201
1537
243
1873
1.64
5.81
8.2
9.4
0.2
0.2
e9/l
0.89
211
1616
256
2004
1.64
5.71
4.9
3.4
37.6
37.0
mmol/mol
0.30
247
1902
45
207
2.27
5.69
2.3
1.6
498.9
300.2
mu/l
1.75
40
189
237
1823
1.63
5.65
7.6
8.7
0.6
0.6
e9/l
0.24
202
1540
159
1115
1.64
5.47
5.0
6.8
13.8
15.1
umol/l
0.24
152
1044
103
652
1.73
5.18
2.0
1.5
98.2
95.7
pmol/l
0.23
59
361
223
1716
1.58
5.12
7.8
8.8
0.7
0.6
%
0.16
209
1648
222
1710
1.58
5.05
9.6
9.9
0.0
0.0
e9/l
1.07
174
1309
58
311
1.96
4.95
4.6
3.8
—
—
—
0
0
149
1054
1.60
4.83
2.8
3.0
—
—
—
0
0
19
62
3.11
4.70
6.9
8.1
—
—
—
0
0
28
115
2.49
4.56
6.9
15.5
128.3
126.8
g/l
0.13
28
110
101
659
1.66
4.49
6.2
4.2
1.1
1.1
inr
0.06
31
199
47
243
2.01
4.44
3.4
11.4
1.3
1.4
mmol/l
0.15
42
221
224
1763
1.52
4.40
7.8
8.6
2.8
3.2
%
1.69
211
1689
148
1067
1.56
4.34
3.9
4.7
14.2
40.5
e6/l
2.14
100
721
239
1911
1.52
4.33
7.7
8.5
2.3
2.2
e9/l
0.84
208
1662
225
1778
1.52
4.30
7.9
8.7
8.2
8.2
%
0.14
214
1711
80
497
1.72
4.25
4.0
10.2
—
—
—
0
0
101
670
1.63
4.19
2.7
3.0
—
—
—
0
0
82
517
1.69
4.13
3.7
4.1
—
—
—
0
0
20
457
0.40
4.08
1.2
1.3
—
—
—
0
0
93
619
1.61
3.78
3.1
3.0
1.0
1.0
kg/l
0.25
11
105
16
54
2.99
3.77
2.6
2.1
—
—
—
0
0
9
260
0.33
3.71
1.3
1.3
—
—
—
0
0
30
140
2.19
3.71
6.4
16.1
93.8
96.0
%
0.39
30
135
18
66
2.75
3.68
4.2
11.4
—
—
—
0
0
33
161
2.10
3.66
6.3
14.2
1.6
0.3
mmol/l
1.16
28
131
33
161
2.10
3.66
5.1
14.2
12.2
15.4
kpa
2.74
33
153
33
161
2.10
3.66
5.1
14.2
5.4
5.2
kpa
0.40
33
153
65
399
1.71
3.60
3.5
2.5
—
—
—
0
0
124
893
1.51
3.55
3.4
4.1
13.1
113.2
e6/l
0.78
97
692
283
2399
1.47
3.48
4.2
2.9
4.3
4.5
mmol/l
4.41
276
2275
83
548
1.61
3.47
3.1
8.5
1.1
1.3
mmol/l
0.26
61
425
226
1837
1.45
3.46
7.5
8.3
51.6
51.4
%
0.10
215
1774
269
2264
1.46
3.39
3.8
2.7
1.3
1.2
mmol/l
1.70
262
2139
63
391
1.68
3.35
1.7
1.6
—
—
—
0
0
50
784
0.58
3.34
1.7
1.9
—
—
—
0
0
84
562
1.58
3.32
1.7
1.7
1.5
1.4
mmol/l
0.59
76
512
103
722
1.53
3.32
2.6
3.1
3.2
2.6
mg/l
0.74
96
638
281
2394
1.45
3.25
4.3
2.9
2.7
2.8
mmol/l
1.35
272
2247
115
829
1.50
3.24
3.3
3.8
0.2
0.2
e6/l
0.11
87
631
279
2380
1.44
3.16
4.0
2.8
1.3
1.4
mmol/l
4.04
272
2249
59
367
1.67
3.12
3.3
2.7
—
—
—
0
0
87
596
1.55
3.10
3.0
3.1
622.2
599.1
mosm/kgh2o
0.29
74
518
227
1874
1.41
3.04
7.9
8.4
33.7
33.8
%
0.07
217
1807
57
354
1.67
3.03
3.5
3.9
26.0
133.9
mg/l
2.84
41
263
14
50
2.81
3.01
1.6
10.7
—
—
—
0
0
115
842
1.47
2.98
3.2
3.7
—
—
—
0
0
57
358
1.65
2.91
4.3
4.6
7.0
16.0
mg/mmol
0.97
40
263
8
17
4.69
2.88
1.1
1.1
—
—
—
0
0
29
153
1.93
2.65
1.4
1.3
—
—
—
0
0
8
19
4.20
2.64
2.5
3.1
227.0
151.5
ug/g
—
8
19
368
3357
1.57
2.61
11.0
7.6
—
—
—
0
0
15
61
2.47
2.55
1.7
1.4
—
—
—
0
0
14
55
2.55
2.55
3.3
9.0
1.6
2.7
mmol/l
—
9
25
22
108
2.06
2.45
6.9
15.4
1.8
1.3
%
0.74
22
108
17
75
2.28
2.44
2.4
2.0
—
—
—
0
0
63
428
1.52
2.33
3.2
2.5
—
—
—
0
0
104
781
1.41
2.31
5.0
6.4
88.8
89.3
%
0.08
104
770
71
496
1.49
2.30
5.7
7.2
7.4
7.4
ph
—
5
21
12
46
2.61
2.30
2.8
3.8
18.1
17.5
%
—
6
28
361
3305
1.48
2.24
11.7
9.7
21.8
22.2
mg/l
0.08
266
2307
344
3124
1.43
2.21
18.6
13.1
13.2
13.1
%
0.76
338
3077
89
656
1.42
2.19
3.9
3.5
0.0
0.0
estimate
0.50
24
253
14
60
2.34
2.16
2.1
7.1
—
—
—
0
0
21
107
1.98
2.14
7.2
15.6
0.6
0.7
%
0.35
21
107
11
42
2.62
2.13
1.5
1.7
—
—
—
0
0
66
462
1.48
2.13
3.1
2.4
—
—
—
0
0
66
462
1.48
2.13
3.1
2.4
—
—
—
0
0
7
19
3.66
2.12
1.0
2.2
—
—
—
0
0
66
464
1.47
2.08
3.2
2.4
—
—
—
0
0
241
2087
1.31
2.02
3.7
4.0
7.8
7.2
mm/h
0.32
225
1963
99
1228
0.73
2.02
2.3
2.2
—
—
—
0
0
75
969
0.71
1.96
2.0
1.7
—
—
—
0
0
17
84
2.03
1.90
7.5
20.8
—
—
—
0
0
40
258
1.58
1.88
2.3
2.1
2.4
2.4
mmol/l
0.24
33
227
160
1321
1.31
1.88
3.4
3.2
0.0
0.0
estimate
0.00
28
248
64
457
1.44
1.87
3.2
2.2
—
—
—
0
0
406
3845
1.81
1.84
20.8
14.3
265.5
262.0
e9/l
0.50
390
3706
22
121
1.83
1.83
3.0
3.0
—
—
—
0
0
81
610
1.38
1.76
3.0
3.3
10.5
5.5
e6/l
1.32
72
535
406
3851
1.77
1.74
20.6
14.2
86.9
87.2
fl
0.61
401
3804
406
3851
1.77
1.74
20.7
14.2
4.8
4.7
e12/l
2.02
390
3708
406
3851
1.77
1.74
20.6
14.2
29.1
29.4
pg
1.84
401
3803
406
3854
1.75
1.69
20.9
14.4
138.2
137.3
g/l
0.62
401
3805
406
3856
1.74
1.65
20.9
14.3
6.8
6.7
e9/l
0.49
390
3712
75
942
0.74
1.62
2.0
1.7
—
—
—
0
0
72
543
1.36
1.56
3.2
2.2
14.1
59.9
ng/l
0.58
41
199
53
380
1.42
1.54
3.5
3.0
164.8
1650.3
ng/l
2.75
32
195
7
27
2.57
1.49
1.1
1.1
—
—
—
0
0
157
1326
1.26
1.48
4.4
4.5
0.0
0.0
estimate
0.00
27
266
158
1337
1.26
1.46
3.4
3.2
0.0
0.0
estimate
0.00
28
251
12
58
2.06
1.44
11.2
15.9
25.2
23.8
mmol/l
0.70
12
52
9
39
2.29
1.41
4.6
15.4
1.1
0.9
%
—
9
34
0
37
0.00
1.35
0.0
1.4
—
42.7
—
0
5
0
37
0.00
1.35
0.0
1.1
—
—
—
0
0
5
17
2.91
1.33
1.0
1.0
—
—
—
0
0
5
17
2.91
1.33
3.0
1.5
—
—
—
0
0
9
172
0.50
1.32
1.2
1.5
—
—
—
0
0
74
902
0.77
1.29
2.4
1.9
—
—
—
0
0
6
24
2.48
1.28
1.0
1.8
8.3
8.9
umol/l
—
6
24
6
24
2.48
1.28
1.0
1.1
—
—
nmol/l
—
0
0
6
24
2.48
1.28
1.2
1.1
—
—
—
0
0
8
36
2.21
1.23
2.6
3.7
—
85.8
—
0
10
15
84
1.78
1.22
3.4
13.1
23.9
23.4
mmol/l
0.26
15
73
6
25
2.38
1.22
1.2
1.1
—
—
—
0
0
219
1949
1.21
1.21
4.1
3.8
—
—
—
0
0
8
149
0.52
1.16
4.8
4.0
6.9
10.4
umol/l
—
8
119
71
561
1.29
1.14
4.1
2.3
—
—
—
0
0
8
39
2.04
1.13
1.9
15.4
1.7
1.4
%
—
8
33
5
20
2.47
1.13
1.2
1.8
4.5
6.3
ug/l
—
5
20
5
20
2.47
1.13
1.2
1.1
—
—
—
0
0
7
31
2.24
1.09
3.6
1.9
—
—
—
0
0
7
32
2.17
1.07
1.6
1.7
—
0.6
u/ml
—
0
7
5
21
2.36
1.07
6.6
26.1
11.0
11.5
mmol/l
—
5
16
5
21
2.36
1.07
6.6
26.1
106.6
105.3
mmol/l
—
5
16
40
294
1.37
1.05
3.7
2.7
16986.9
3758.0
u/l
—
9
127
9
45
1.99
1.04
1.1
1.1
—
—
—
0
0
9
46
1.94
1.03
2.2
5.3
24.3
24.7
umol/l
—
9
46
15
90
1.66
0.99
1.4
1.5
—
—
—
0
0
11
60
1.82
0.99
4.0
7.9
—
—
—
0
0
7
35
1.98
0.98
1.1
1.1
—
—
—
0
0
6
116
0.50
0.95
1.0
1.1
—
—
—
0
0
11
61
1.79
0.94
1.3
13.2
—
—
—
0
0
6
27
2.20
0.93
3.7
2.6
—
—
—
0
0
12
70
1.70
0.88
1.0
1.4
435.8
366.0
ug/g
—
5
35
27
192
1.41
0.87
6.6
5.0
0.0
0.1
%
—
8
59
26
184
1.41
0.87
6.7
5.1
0.0
0.1
%
—
7
52
30
218
1.38
0.86
1.5
2.3
0.8
1.0
ug/l
0.55
25
198
12
71
1.68
0.85
1.2
1.2
—
—
—
0
0
8
135
0.57
0.85
1.6
1.1
—
—
—
0
0
8
136
0.57
0.85
1.6
1.1
—
—
—
0
0
13
79
1.64
0.84
1.4
1.1
—
—
—
0
0
10
162
0.60
0.83
1.4
1.5
—
—
—
0
0
32
237
1.35
0.83
1.9
2.0
10.5
11.6
iu/l
0.12
20
165
0
25
0.00
0.79
0.0
6.5
—
—
—
0
0
23
308
0.72
0.79
1.3
1.3
0.8
2.0
u/ml
0.82
18
196
65
534
1.23
0.78
1.2
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
4.7
—
2.7
—
0
11
10
159
0.61
0.78
1.4
1.4
—
—
—
0
0
10
159
0.61
0.78
1.4
1.4
—
—
—
0
0
35
266
1.32
0.78
1.6
1.9
1.1
1.0
g/l
0.40
35
254
9
55
1.62
0.73
1.1
1.2
—
—
—
0
0
7
39
1.78
0.72
5.9
15.6
0.8
1.2
mmol/l
—
7
30
27
200
1.35
0.71
6.6
4.9
0.3
0.7
%
—
8
64
13
84
1.54
0.68
2.7
2.3
—
—
—
0
0
5
27
1.83
0.67
1.0
1.2
—
—
—
0
0
73
826
0.84
0.65
1.7
1.7
—
—
—
0
0
132
1175
1.15
0.65
1.7
1.6
1.7
1.8
g/l
0.11
69
636
8
126
0.62
0.65
1.3
1.6
—
9.0
—
0
7
21
275
0.74
0.65
1.2
1.2
0.5
4.0
u/ml
—
8
91
32
248
1.29
0.64
1.8
2.0
4.5
6.1
u/l
0.76
18
168
14
94
1.48
0.63
3.6
3.6
—
—
—
0
0
45
366
1.23
0.62
2.2
2.5
335.1
355.0
nmol/l
0.26
45
348
9
137
0.64
0.61
1.0
1.1
—
—
—
0
0
0
19
0.00
0.60
0.0
1.4
—
—
—
0
0
17
121
1.40
0.58
1.2
1.3
—
—
—
0
0
6
34
1.74
0.58
8.7
2.8
9.7
5.4
mmol/l
—
6
28
44
360
1.22
0.58
1.2
1.3
—
300.8
—
0
12
11
158
0.68
0.57
1.3
2.0
—
—
—
0
0
65
554
1.18
0.56
2.6
3.4
2.1
1.0
mg/l
0.90
44
377
21
157
1.33
0.55
3.3
9.2
0.2
0.3
g/l
1.58
11
130
13
89
1.45
0.54
1.2
1.1
—
—
—
0
0
22
167
1.31
0.52
1.2
1.1
—
—
—
0
0
9
62
1.44
0.52
2.9
4.3
—
—
—
0
0
29
229
1.26
0.52
2.2
4.4
71.8
65.5
e9/l
0.27
17
141
6
39
1.52
0.52
5.2
2.1
—
—
—
0
0
140
1272
1.12
0.50
1.8
1.7
1.7
2.6
u/ml
0.29
23
235
38
313
1.21
0.48
2.3
2.0
11.1
13.3
nmol/l
0.93
31
262
7
48
1.44
0.46
7.9
2.7
0.6
1.9
%
—
7
36
31
366
0.82
0.46
1.1
1.6
—
—
—
0
0
16
119
1.33
0.44
2.5
1.9
—
—
—
0
0
23
279
0.80
0.44
1.2
1.2
0.6
0.8
u/ml
0.31
16
200
5
31
1.59
0.42
2.8
1.3
—
—
—
0
0
5
31
1.59
0.42
1.0
1.3
—
—
—
0
0
28
227
1.23
0.42
1.9
2.1
—
16.9
—
0
18
8
56
1.41
0.42
5.4
5.8
3.0
2.0
ug/l
—
8
56
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
4.9
—
—
—
0
0
0
16
0.00
0.41
0.0
3.6
—
—
—
0
0
13
95
1.36
0.40
2.5
5.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
8
60
1.32
0.39
5.0
4.2
3.6
3.2
e9/l
—
8
60
11
145
0.74
0.38
1.1
1.1
—
4.2
—
0
8
24
284
0.82
0.37
1.2
1.2
2.2
7.4
u/ml
3.69
18
219
51
445
1.14
0.36
6.5
6.8
—
—
—
0
0
19
229
0.81
0.35
1.5
1.4
—
—
—
0
0
6
42
1.41
0.35
1.0
2.8
—
—
—
0
0
21
169
1.23
0.35
1.7
1.5
—
—
—
0
0
64
694
0.89
0.35
2.8
3.2
64.9
114.5
ug/g
1.59
55
561
6
45
1.31
0.33
1.2
1.0
—
—
—
0
0
6
46
1.29
0.32
1.7
9.2
—
—
—
0
0
7
51
1.35
0.31
1.6
1.9
155.0
138.9
ng/l
—
7
51
32
274
1.16
0.29
1.5
1.4
—
—
—
0
0
7
55
1.26
0.29
1.1
1.5
—
—
—
0
0
348
3478
0.91
0.29
16.3
11.9
40.6
40.4
%
0.16
293
3094
25
285
0.85
0.28
2.0
2.0
—
—
—
0
0
8
61
1.29
0.28
5.0
4.3
51.6
51.4
%
—
8
61
18
211
0.83
0.27
1.1
1.1
—
—
—
0
0
14
113
1.23
0.24
2.1
1.6
—
—
—
0
0
13
155
0.82
0.23
1.3
1.1
0.0
0.4
u/ml
—
5
69
0
10
0.00
0.21
0.0
2.7
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
15
174
0.84
0.21
1.2
1.1
0.8
7.4
u/ml
—
10
97
0
13
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
12.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
9
113
0.78
0.20
1.9
1.8
—
—
—
0
0
11
131
0.82
0.20
2.3
1.6
30.8
36.2
nmol/l
0.30
11
126
39
350
1.10
0.20
2.4
2.0
—
—
—
0
0
70
728
0.93
0.18
3.7
2.9
—
—
—
0
0
13
150
0.85
0.17
1.2
1.6
—
—
—
0
0
41
436
0.92
0.17
3.5
4.7
30.1
30.4
s
0.21
41
431
7
61
1.13
0.17
7.6
4.8
—
—
—
0
0
14
160
0.86
0.17
1.2
1.1
4.5
9.7
u/ml
—
9
93
5
65
0.75
0.17
1.2
1.1
—
—
—
0
0
5
67
0.73
0.17
4.0
3.4
258.0
235.6
e6/l
—
5
41
17
146
1.15
0.16
2.3
4.6
—
—
—
0
0
18
200
0.88
0.16
1.3
1.4
288.3
262.0
miu/ml
—
7
101
6
76
0.77
0.15
5.8
4.9
2.4
4.3
u/ml
—
6
71
106
1080
0.95
0.14
1.4
1.7
—
—
—
0
0
125
1190
1.05
0.14
3.8
4.0
—
—
—
0
0
8
95
0.82
0.14
1.1
1.1
—
—
—
0
0
11
125
0.86
0.12
1.6
1.7
—
—
—
0
0
18
196
0.90
0.12
1.1
1.9
178.2
169.5
u/ml
0.09
13
101
32
336
0.93
0.11
1.8
1.4
304.7
324.2
u/ml
0.04
32
316
46
429
1.06
0.11
1.7
4.1
331.7
2039.0
umol/l
0.79
39
397
11
123
0.88
0.10
1.4
1.1
—
—
—
0
0
6
53
1.11
0.09
1.0
1.1
—
—
—
0
0
10
86
1.15
0.09
1.1
1.2
—
—
—
0
0
7
64
1.08
0.08
1.0
1.0
7.8
9.2
mu/l
—
7
57
26
240
1.07
0.08
4.2
3.5
—
—
—
0
0
7
67
1.03
0.08
3.1
3.1
386.4
529.5
e6/l
—
7
46
7
67
1.03
0.08
3.1
3.1
0.1
0.2
e9/l
—
7
47
6
71
0.83
0.07
3.5
3.8
17.7
12.2
%
—
6
71
8
72
1.09
0.07
1.1
1.2
—
—
—
0
0
8
74
1.06
0.07
3.3
6.6
—
—
—
0
0
33
309
1.05
0.07
1.9
1.4
—
—
—
0
0
156
1510
1.02
0.06
3.1
3.2
408.6
70.2
ug/l
0.49
143
1432
43
409
1.04
0.05
1.3
1.2
10.5
19.2
iu/ml
—
8
98
19
177
1.06
0.04
1.2
1.2
—
—
—
0
0
31
294
1.04
0.03
1.3
1.3
50.2
140.1
iu/ml
—
8
112
86
833
1.02
0.03
2.4
2.7
—
—
—
0
0
34
342
0.98
0.01
8.3
13.0
5.3
5.7
mmol/l
0.41
34
336
45
435
1.02
0.01
1.5
1.5
260.0
477.7
titre
—
6
70
10
92
1.07
0.01
1.2
1.3
—
—
—
0
0
17
173
0.96
0.00
1.2
1.2
—
—
—
0
0
64
635
0.99
0.00
2.1
1.6
—
—
—
0
0
72
702
1.01
0.00
7.3
5.1
—
—
—
0
0
13
126
1.01
0.00
1.4
1.5
1.2
1.2
g/l
0.23
13
120
26
254
1.01
0.00
1.2
1.2
—
—
—
0
0
40
388
1.01
0.00
1.8
1.5
—
—
—
0
0
40
391
1.01
0.00
1.3
1.2
19.1
7.0
u/ml
0.30
15
136
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
1786.9
—
0
8
0
9
0.00
0.00
0.0
3.6
—
14.1
—
0
9
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.88
0.00
3.5
3.4
70.8
70.6
%
—
6
67
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
15.6
—
0
6
6
60
0.98
0.00
1.7
14.7
73.3
72.7
%
—
6
60
5
58
0.85
0.00
1.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
5
58
0.85
0.00
1.0
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
6
60
0.98
0.00
3.5
3.3
26.7
26.0
%
—
6
60
0
7
0.00
0.00
0.0
4.4
—
0.4
—
0
7
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.85
0.00
1.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
12.2
—
24.0
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
140.0
—
0
5
0
7
0.00
0.00
0.0
3.7
—
6.6
—
0
7
0
6
0.00
0.00
0.0
21.8
—
14.5
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
65.0
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
190.4
—
0
5
5
58
0.85
0.00
1.0
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint F5_PSYCHDEVOTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_PSYCHDEVOTH.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: F5_PSYCHDEVOTH – Other and unspecified disorders of psychological development

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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