Other abnormal auditory perceptions

H8_ABNAUDPER

auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H93.2
  • Cause of death: ICD-10 H93.2

2 out of 7 registries used, show all original rules.

423

4. Check minimum number of events

None

423

5. Include endpoints

None

423

6. Filter based on genotype QC (FinnGen only)

406

Control definitions (FinnGen only)

Control exclude
H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H93
Name in latin
Aliae perceptiones auditoriae abnormes

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2549 1593 947
Only index persons 2466 1555 911
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.05 0.06 0.03
Median age at first event (years)
Whole population 46.50 48.98 42.40
Only index persons 46.89 49.24 42.89

-FinnGen-

Key figures

All Female Male
Number of individuals 406 293 113
Unadjusted period prevalence (%) 0.09 0.10 0.05
Median age at first event (years) 50.00 50.16 49.59

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
423
Matched controls
4230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H93.2
ICD-10 Finland
Other abnormal auditory perceptions
4503599627370496.0
307.7
422
10
H93.1
ICD-10 Finland
Tinnitus
38.6
190.2
124
45
DFF00
NOMESCO Finland
Pure tone audiometry
28.0
167.9
123
61
Z01.1
ICD-10 Finland
Examination of ears and hearing
14.6
147.3
162
172
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
39.4
139.1
88
28
UDC00
NOMESCO Finland
Ear microscopy
9.7
55.1
70
85
N07CA01
ATC
betahistine; oral
8.7
49.9
69
93
H02
ICPC
Hearing complaint
6.3
45.5
87
166
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
56.0
30.8
36
7
SPAT1043
SPAT
Audiometry
5.9
30.8
60
115
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
300.4
28.1
28
*
H91.9
ICD-10 Finland
Hearing loss, unspecified
8.7
26.0
34
42
H29
ICPC
Ear symptom/complaint other
3.7
20.0
70
213
R42
ICD-10 Finland
Dizziness and giddiness
2.9
19.6
118
499
H92.0
ICD-10 Finland
Otalgia
4.7
19.3
48
113
DFF15
NOMESCO Finland
Speech audiometry
22.1
18.9
27
13
Z3229
NOMESCO Finland
Other healthcare associate professional
3.8
14.8
48
138
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
44.1
14.2
17
*
H01
ICPC
Ear pain/earache
2.7
13.0
78
324
R51.80
ICD-10 Finland
Headache
2.4
12.0
95
450
P06
ICPC
Sleep disturbance
2.7
12.0
70
286
H03
ICPC
Tinnitus, ringing/buzzing ear
6.1
11.9
21
36
Z97.4
ICD-10 Finland
Presence of external hearing-aid
23.7
11.6
16
7
R01AD09
ATC
mometasone; nasal
2.0
11.4
220
1474
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.1
11.1
48
166
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
11.1
185
1175
G44.2
ICD-10 Finland
Tension-type headache
2.4
10.5
84
398
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
112.7
10.5
11
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
10.4
178
1133
H66.9
ICD-10 Finland
Otitis media, unspecified
3.0
9.7
44
156
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
9.6
62
265
H13
ICPC
Plugged feeling ear
2.3
9.6
80
385
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
7.2
9.4
22
32
M01AH01
ATC
celecoxib; oral
2.3
9.0
80
395
DAX08
NOMESCO Finland
Fitting of hearing aid
19.1
9.0
13
7
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
51.1
8.7
10
*
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
28.2
8.5
11
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
8.5
244
1800
N05BA04
ATC
oxazepam; oral
2.0
8.5
124
739
R06AE07
ATC
cetirizine; oral
1.8
8.3
200
1396
K07.60
ICD-10 Finland
Snapping jaw
3.0
8.3
38
136
H81.0
ICD-10 Finland
Ménière disease
8.4
8.2
17
21
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.7
8.0
45
179
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
8.0
7.9
17
22
L01
ICPC
Neck symptom/complaint
2.1
7.9
79
409
Z2445
NOMESCO Finland
Psychologist
3.0
7.8
35
123
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
7.8
34
118
R5120
NOMESCO Finland
Preparation of an aid
9.1
7.6
15
17
SPAT1081
SPAT
Cardiorespiratory global assessment
3.8
7.6
23
63
D06
ICPC
Abdominal pain localized other
2.6
7.4
46
193
L17
ICPC
Foot/toe symptom/complaint
1.9
7.4
130
818
A02BC02
ATC
pantoprazole; systemic
1.8
7.4
277
2175
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.3
7.3
62
299
R52.9
ICD-10 Finland
Pain, unspecified
2.4
7.3
52
233
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.5
7.2
48
208
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
7.1
155
1040
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.2
7.1
61
297
A11
ICPC
Chest pain NOS
2.7
7.0
38
149
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.3
6.9
56
265
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
6.9
113
693
N06AX22
ATC
agomelatine; oral
4.4
6.8
17
40
D02
ICPC
Abdominal pain epigastric
2.9
6.8
32
116
R01AD08
ATC
fluticasone; nasal
1.8
6.7
131
846
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
6.7
81
448
A02BC05
ATC
esomeprazole; systemic
1.7
6.7
170
1185
A01
ICPC
Pain general/multiple sites
2.4
6.6
47
210
L29
ICPC
Musculoskeletal sympt/complt other
2.5
6.5
42
180
C07AA05
ATC
propranolol; systemic
1.9
6.5
102
617
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
6.4
94
556
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.9
6.4
30
109
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
6.3
127
827
H91.1
ICD-10 Finland
Presbycusis
7.2
6.3
14
20
SPAT1153
SPAT
Removal of sutures
1.8
6.3
121
778
S29
ICPC
Skin symptom/complaint other
1.9
6.3
83
474
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
27.1
6.2
8
*
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.4
6.2
22
67
R01AD12
ATC
fluticasone furoate; nasal
1.7
6.1
145
986
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
6.1
65
343
S18
ICPC
Laceration/cut
1.7
6.1
179
1290
SPAT1301
SPAT
No procedures
1.8
6.1
125
817

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
335
2602
2.38
12.01
4.7
3.8
9.32
10.72
mm/h
1.39
325
2429
348
2779
2.42
11.19
4.8
4.1
14.64
14.57
pmol/l
0.22
325
2571
179
1203
1.85
8.44
2.2
1.9
101.05
97.18
pmol/l
0.51
95
630
215
1541
1.80
8.11
6.7
6.3
1.23
1.22
mmol/l
0.95
190
1326
399
3539
3.25
7.99
15.2
13.1
3.91
3.94
mmol/l
1.21
393
3442
381
3303
2.55
7.99
5.8
4.7
1.80
2.18
mu/l
0.53
365
3081
397
3532
3.02
7.50
15.2
13.0
139.91
139.65
mmol/l
1.60
391
3445
246
1870
1.75
7.28
4.2
4.2
6.16
6.52
mmol/l
3.46
230
1732
88
491
2.00
7.14
1.6
1.7
1110.59
1192.28
nmol/l
0.39
70
377
199
1432
1.74
7.10
2.6
2.3
78.58
75.14
nmol/l
0.98
187
1311
136
881
1.80
6.96
1.4
1.3
0.79
2.37
u/ml
1.50
40
242
192
1395
1.69
6.42
6.3
5.6
1.22
1.22
mmol/l
0.23
175
1296
312
2588
1.78
6.33
7.0
7.1
75.50
78.94
u/l
0.87
294
2452
260
2054
1.69
6.27
8.2
9.2
4.12
4.01
e9/l
0.20
230
1801
32
122
2.76
6.22
1.2
1.2
—
—
—
0
0
215
1631
1.65
5.94
2.8
2.7
98.04
89.62
ug/l
0.44
204
1524
66
359
1.99
5.70
1.4
1.3
—
—
—
0
0
120
795
1.71
5.50
1.7
1.8
0.79
1.13
mg/l
1.19
89
593
233
1834
1.60
5.33
5.9
6.2
0.18
0.19
e9/l
0.16
209
1633
405
3736
2.98
5.31
13.4
10.9
—
—
—
0
0
406
3759
2.99
5.11
10.9
9.6
25.48
25.82
u/l
0.16
396
3660
391
3561
2.30
5.07
15.5
11.9
19.28
21.05
mg/l
0.61
330
2747
225
1771
1.58
5.04
5.6
5.8
0.52
0.55
e9/l
1.70
196
1548
214
1667
1.57
5.00
6.1
6.4
—
—
—
0
0
27
106
2.65
4.98
1.1
1.1
1.55
12.29
u/ml
—
6
14
176
1311
1.59
4.98
4.3
4.4
37.12
36.41
g/l
1.02
169
1243
207
1603
1.57
4.94
5.8
5.9
0.70
0.69
%
0.20
192
1496
213
1664
1.56
4.87
6.0
6.1
8.21
8.25
%
0.07
198
1567
286
2391
1.61
4.86
5.0
3.9
—
—
—
0
0
212
1657
1.56
4.82
5.7
5.9
2.95
2.83
%
0.35
197
1557
224
1776
1.56
4.75
5.7
5.9
0.04
0.04
e9/l
0.21
196
1550
32
140
2.39
4.74
3.2
2.2
—
—
—
0
0
116
789
1.65
4.73
1.4
1.5
2.05
2.22
g/l
0.90
74
493
229
1827
1.55
4.71
5.8
5.8
1.77
1.98
e9/l
1.98
207
1642
352
3114
1.78
4.69
5.1
5.0
37.80
38.77
mmol/mol
1.70
329
2934
79
487
1.77
4.61
2.4
2.4
94.53
115.70
ug/g
0.32
63
382
128
901
1.60
4.52
1.7
1.7
1.28
1.41
mmol/l
0.98
122
779
78
483
1.75
4.48
1.8
2.2
14.26
13.16
umol/l
0.69
73
453
216
1717
1.53
4.41
5.8
5.9
28.37
28.84
%
0.27
201
1621
214
1699
1.53
4.39
5.6
5.8
56.65
56.75
%
0.05
198
1603
215
1718
1.51
4.22
4.8
6.1
10.34
10.60
umol/l
0.17
201
1635
153
1143
1.53
4.10
3.4
3.2
19.61
31.95
ng/l
1.63
76
698
78
499
1.69
3.97
1.4
1.4
338.46
494.87
titre
0.69
13
113
95
641
1.62
3.94
1.4
1.2
4.39
9.25
u/ml
0.84
42
266
70
440
1.71
3.80
1.1
1.2
—
—
—
0
0
287
2469
1.51
3.72
3.0
2.8
37.19
40.65
u/l
0.59
270
2345
272
2332
1.47
3.45
3.6
3.4
—
—
—
0
0
375
3452
1.76
3.41
4.6
4.0
4.79
4.75
mmol/l
0.33
353
3253
379
3501
1.79
3.38
4.9
4.4
2.88
2.83
mmol/l
0.58
358
3279
45
257
1.84
3.38
4.2
4.5
—
—
—
0
0
363
3315
1.67
3.37
3.8
3.6
1.26
1.26
mmol/l
0.04
341
3093
18
72
2.57
3.25
1.3
1.7
—
—
—
0
0
169
1339
1.44
3.21
9.6
9.6
1.16
1.16
inr
0.00
42
431
32
166
2.00
3.19
4.0
4.1
—
—
—
0
0
92
647
1.54
3.16
1.4
1.3
18.01
33.58
iu/ml
1.61
27
222
89
623
1.54
3.12
1.4
1.7
459.25
24226301.00
pmol/l
0.77
71
549
53
326
1.72
3.11
2.6
2.1
410.48
370.67
nmol/l
1.00
46
307
105
769
1.49
2.97
3.8
3.8
—
—
—
0
0
66
439
1.60
2.88
1.7
2.1
2.33
2.42
g/l
0.62
61
410
173
1397
1.40
2.88
2.3
2.0
—
—
—
0
0
106
783
1.47
2.86
2.3
2.0
2.55
3.08
mg/l
1.54
97
664
132
1017
1.43
2.86
2.2
2.4
53.35
61.71
u/l
0.82
124
955
370
3433
1.62
2.77
4.5
4.0
1.51
1.51
mmol/l
0.09
351
3217
37
213
1.81
2.74
1.3
1.2
—
—
—
0
0
27
141
1.98
2.67
1.3
1.5
—
9.23
—
0
6
119
911
1.43
2.65
4.0
2.7
—
—
—
0
0
14
55
2.60
2.64
2.1
2.1
13.64
13.14
%
0.59
14
55
32
180
1.84
2.55
1.0
1.1
—
—
—
0
0
97
720
1.45
2.54
1.6
1.5
19.63
21.73
nmol/l
0.79
82
622
361
3346
1.54
2.54
4.5
4.0
5.69
5.80
mmol/l
1.07
340
3096
35
203
1.79
2.54
2.8
3.2
66.81
193.49
ng/l
4.09
35
187
11
37
3.02
2.50
1.6
2.2
—
—
—
0
0
52
338
1.61
2.50
2.7
2.4
28.52
32.56
u/l
0.54
44
289
205
1733
1.35
2.47
4.8
4.6
0.00
0.00
estimate
0.50
36
346
33
191
1.79
2.42
2.2
2.1
15.14
12.50
nmol/l
1.07
28
179
109
834
1.41
2.41
4.0
3.4
—
—
—
0
0
206
1755
1.34
2.31
3.6
3.3
0.00
0.00
estimate
-0.00
34
331
38
233
1.69
2.29
1.2
1.5
—
—
—
0
0
10
34
2.99
2.29
2.3
1.2
—
—
—
0
0
80
585
1.45
2.26
5.7
3.8
81.24
348.09
ng/l
2.18
55
415
127
1008
1.37
2.25
4.4
2.8
12.80
53.57
e6/l
3.08
103
768
9
29
3.15
2.24
1.4
1.7
—
—
—
0
0
117
921
1.37
2.17
4.3
2.7
0.11
0.46
e6/l
4.13
96
690
202
1729
1.32
2.14
3.5
3.3
0.00
0.00
estimate
0.50
36
359
26
146
1.83
2.11
2.4
1.8
—
—
—
0
0
115
908
1.37
2.09
7.3
6.9
—
—
—
0
0
144
1178
1.34
2.08
3.5
3.1
26.94
30.81
u/l
2.07
139
1130
5
10
5.04
2.07
3.4
3.2
58.20
56.50
%
—
5
10
13
56
2.36
2.07
1.1
1.2
—
—
—
0
0
109
855
1.37
2.06
3.2
3.5
99.76
95.09
%
1.56
102
834
23
126
1.87
2.02
1.2
1.1
—
—
—
0
0
146
1201
1.33
2.02
5.1
3.3
25.15
79.50
e6/l
1.76
109
822
61
434
1.47
1.98
2.4
1.9
—
—
—
0
0
47
317
1.54
1.96
5.0
7.1
1.37
1.17
mmol/l
0.15
39
258
58
411
1.48
1.93
1.8
2.2
25.65
22.37
%
0.88
49
363
188
1611
1.30
1.92
8.3
8.6
0.00
0.00
e9/l
0.59
156
1321
7
22
3.22
1.88
1.7
1.5
—
—
—
0
0
35
224
1.61
1.83
2.9
2.6
—
—
—
0
0
69
511
1.42
1.83
4.6
2.6
2.63
2.89
e6/l
0.13
41
266
13
257
0.49
1.80
1.7
1.7
—
—
—
0
0
189
1631
1.29
1.79
2.4
2.4
—
—
—
0
0
9
36
2.53
1.75
1.1
1.2
—
—
—
0
0
8
30
2.70
1.73
1.6
2.5
47.40
37.65
%
—
8
30
89
695
1.36
1.72
2.8
2.2
4.25
6.66
e6/l
0.78
80
621
14
69
2.06
1.66
1.3
1.1
4.85
0.65
u/ml
—
7
40
55
398
1.44
1.66
1.5
1.3
—
—
—
0
0
23
135
1.74
1.66
1.6
1.7
—
—
—
0
0
133
1107
1.29
1.65
2.7
3.2
2.36
2.36
mmol/l
0.32
121
1011
130
1082
1.29
1.61
2.1
2.1
—
—
—
0
0
6
20
3.03
1.58
1.0
1.4
1.83
1.91
mmol/l
—
6
20
50
360
1.44
1.56
1.6
1.5
—
—
—
0
0
40
277
1.49
1.51
3.9
4.1
0.07
0.11
%
0.19
14
82
6
21
2.88
1.51
1.3
1.3
—
—
—
0
0
15
80
1.91
1.46
1.2
1.2
2.38
1.96
u/ml
—
7
46
12
59
2.06
1.45
1.3
1.0
8.29
2.26
u/ml
—
6
30
5
16
3.15
1.44
2.6
1.3
—
—
—
0
0
6
22
2.75
1.44
1.2
1.2
—
—
—
0
0
6
22
2.75
1.44
1.0
1.1
—
—
—
0
0
31
206
1.54
1.42
1.0
1.1
—
195.00
—
0
6
76
597
1.33
1.42
5.0
4.4
1.68
2.05
ug/l
0.66
71
530
97
789
1.30
1.42
3.8
3.3
—
—
—
0
0
117
976
1.27
1.41
3.4
3.5
7.39
7.40
ph
0.59
17
186
11
53
2.10
1.39
1.3
1.0
10.96
1.90
u/ml
—
6
22
35
242
1.49
1.35
3.6
3.2
—
—
—
0
0
97
795
1.29
1.34
3.2
2.5
321.56
7987.58
umol/l
3.94
86
707
41
295
1.43
1.30
3.9
4.0
1.07
0.77
%
0.35
15
100
34
236
1.48
1.29
1.6
2.8
60.71
71.27
e9/l
1.98
28
179
41
296
1.43
1.28
1.3
1.2
—
—
—
0
0
28
188
1.52
1.25
2.5
2.3
3861.26
2372.13
u/l
—
8
83
116
981
1.25
1.24
3.3
2.6
—
—
—
0
0
22
141
1.59
1.19
2.9
2.4
0.93
0.64
%
0.48
22
141
11
57
1.95
1.18
2.6
1.5
—
—
—
0
0
39
284
1.41
1.18
4.2
3.8
—
—
—
0
0
65
514
1.31
1.18
2.1
3.4
0.81
0.82
mmol/l
0.17
60
488
37
267
1.42
1.17
4.0
4.1
0.00
0.03
%
—
9
73
23
150
1.56
1.17
7.1
8.7
—
—
—
0
0
33
236
1.43
1.10
1.2
1.2
—
—
—
0
0
14
81
1.75
1.10
3.1
2.5
—
—
—
0
0
5
21
2.40
1.09
1.8
2.0
—
—
—
0
0
16
98
1.66
1.04
2.1
4.1
—
—
—
0
0
5
22
2.29
1.03
1.0
1.2
162.26
171.30
pmol/l
—
5
22
5
23
2.19
0.98
1.0
1.4
—
—
—
0
0
7
36
1.96
0.97
2.9
2.8
—
—
—
0
0
7
36
1.96
0.97
1.0
1.1
—
—
—
0
0
32
234
1.40
0.97
2.8
2.8
3.46
6.09
e9/l
1.25
23
205
31
226
1.40
0.95
1.4
1.4
30.12
24.83
iu/l
0.36
26
193
6
27
2.24
0.94
1.7
2.3
—
—
—
0
0
6
27
2.24
0.94
1.5
1.2
—
—
—
0
0
54
431
1.29
0.93
1.3
1.2
—
—
—
0
0
37
280
1.35
0.92
4.2
3.9
6.00
5.83
kpa
0.49
37
275
6
28
2.16
0.92
1.0
1.2
45.67
33.39
nmol/l
—
6
22
16
102
1.59
0.92
1.1
1.3
—
3.44
—
0
11
90
1049
0.82
0.91
1.5
1.5
—
—
—
0
0
22
152
1.47
0.90
3.3
3.1
—
—
—
0
0
46
362
1.30
0.89
4.2
5.9
104.24
104.36
mmol/l
0.06
46
362
13
79
1.67
0.89
1.2
1.0
—
—
—
0
0
6
30
2.01
0.87
1.2
1.1
—
5.83
—
0
8
89
760
1.22
0.87
3.4
3.3
1.02
1.02
kg/l
0.06
20
106
11
64
1.74
0.87
1.2
1.2
—
—
—
0
0
120
1354
0.84
0.86
2.6
2.6
—
—
—
0
0
36
275
1.34
0.85
3.5
3.9
0.30
0.51
%
—
10
85
6
31
1.95
0.84
2.2
3.9
—
—
—
0
0
17
113
1.53
0.83
1.4
1.2
—
—
—
0
0
19
130
1.48
0.82
2.1
1.8
—
—
—
0
0
14
89
1.59
0.82
1.9
1.7
—
—
—
0
0
106
928
1.19
0.80
4.0
3.5
0.00
0.01
estimate
0.80
37
339
16
106
1.53
0.80
6.1
9.2
—
—
—
0
0
34
436
0.76
0.79
1.1
1.4
—
—
—
0
0
78
665
1.21
0.78
3.4
2.4
499.36
538.78
mosm/kgh2o
0.69
67
568
66
554
1.23
0.77
2.5
2.7
2.42
2.44
mmol/l
0.82
59
497
6
34
1.78
0.76
2.0
2.3
2.05
3.07
nmol/l
—
6
34
40
318
1.28
0.74
1.9
2.8
1.54
1.73
%
1.04
31
291
11
68
1.63
0.72
1.1
1.1
0.99
2.18
u/ml
—
5
32
7
40
1.76
0.71
1.1
1.1
—
—
—
0
0
9
57
1.59
0.71
4.3
1.9
77.04
62.41
%
—
9
57
31
240
1.31
0.70
4.5
6.4
7.02
8.09
mmol/l
0.53
31
229
5
27
1.86
0.68
1.0
1.2
—
—
—
0
0
52
433
1.23
0.66
2.1
1.8
—
—
—
0
0
31
242
1.30
0.66
6.2
8.2
—
—
—
0
0
5
28
1.79
0.66
1.2
1.5
12.87
16.49
ug/l
—
5
28
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
23
175
1.33
0.59
1.1
1.1
—
—
—
0
0
20
149
1.36
0.59
1.7
1.5
—
—
—
0
0
22
167
1.33
0.58
1.8
1.5
—
—
—
0
0
6
39
1.55
0.53
2.3
1.6
—
—
—
0
0
15
109
1.39
0.51
4.1
4.7
0.12
0.41
g/l
—
8
46
9
65
1.39
0.51
4.4
2.2
—
—
—
0
0
92
835
1.13
0.45
2.1
1.9
—
—
—
0
0
14
104
1.36
0.43
2.2
2.4
—
—
—
0
0
43
370
1.18
0.43
1.5
1.5
—
—
—
0
0
6
94
0.63
0.42
6.2
5.1
1.07
1.30
mg/l
—
6
89
21
167
1.27
0.42
1.9
1.5
253.29
299.67
mu/l
0.63
21
150
8
57
1.41
0.42
1.5
2.2
—
—
—
0
0
8
57
1.41
0.42
1.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
36
307
1.19
0.40
3.4
4.3
8.44
21.02
ug/l
0.39
27
252
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
5
36
1.39
0.38
1.4
1.1
—
—
—
0
0
35
406
0.85
0.37
2.1
2.4
11.22
7.56
umol/l
0.31
30
348
10
72
1.40
0.37
2.0
3.6
3.41
4.38
e9/l
—
10
72
42
367
1.16
0.36
3.5
2.7
1.31
0.74
ug/l
0.41
31
225
31
264
1.19
0.36
1.6
1.4
—
—
—
0
0
16
127
1.27
0.34
1.8
1.5
0.23
0.24
g/l
0.07
16
121
16
127
1.27
0.34
17.4
5.3
24.67
25.32
mmol/l
0.91
16
121
22
182
1.22
0.34
1.7
1.5
—
—
—
0
0
10
74
1.36
0.32
2.2
3.9
51.90
56.58
%
—
10
74
6
47
1.28
0.32
1.3
1.3
—
—
—
0
0
22
184
1.21
0.31
1.8
1.5
—
—
—
0
0
22
184
1.21
0.31
1.8
1.5
—
—
—
0
0
22
184
1.21
0.31
1.8
1.5
—
—
—
0
0
7
56
1.25
0.29
1.9
1.2
—
—
—
0
0
7
56
1.25
0.29
1.0
1.4
—
75.08
—
0
5
148
1409
1.08
0.28
3.4
3.0
6.17
5.79
ph
—
6
127
10
76
1.32
0.28
4.2
4.4
—
—
—
0
0
43
477
0.89
0.27
1.6
1.5
—
—
—
0
0
9
76
1.19
0.24
1.2
1.3
—
—
—
0
0
16
133
1.21
0.24
1.7
1.5
1.07
1.20
g/l
1.55
16
125
27
307
0.87
0.24
3.0
3.3
—
—
—
0
0
5
40
1.25
0.22
1.4
1.4
—
—
nmol/l
—
0
0
5
41
1.22
0.22
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
2.4
—
14.97
—
0
12
5
43
1.16
0.21
1.8
2.5
4.12
3.97
mmol/l
—
5
43
5
43
1.16
0.21
2.8
1.6
—
—
—
0
0
5
43
1.16
0.21
1.8
2.5
107.20
105.63
mmol/l
—
5
43
5
43
1.16
0.21
1.8
2.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
213.13
—
0
13
6
48
1.25
0.20
1.3
1.4
—
—
—
0
0
102
971
1.07
0.20
3.2
3.1
7.92
7.75
mmol/l
0.12
84
833
53
492
1.09
0.19
1.8
1.7
—
—
—
0
0
93
885
1.07
0.19
3.5
3.7
3.08
9.61
mg/mmol
2.43
54
540
7
58
1.21
0.18
4.1
4.2
—
—
—
0
0
8
69
1.16
0.16
1.6
1.4
24907.00
17959.52
e6/l
—
8
52
8
70
1.15
0.16
2.5
3.0
1.29
1.58
mmol/l
—
8
70
88
842
1.06
0.15
3.1
3.2
17.91
380.79
mg/l
1.58
54
534
11
94
1.17
0.13
1.1
1.3
—
73.33
—
0
6
21
192
1.10
0.11
13.8
4.4
—
7.41
—
0
22
30
280
1.08
0.10
1.5
1.4
—
—
—
0
0
5
45
1.11
0.10
2.0
2.6
—
—
—
0
0
10
87
1.15
0.09
1.2
1.2
—
—
—
0
0
11
124
0.88
0.09
2.1
1.2
—
—
—
0
0
21
194
1.09
0.09
13.8
4.4
5.04
5.16
kpa
0.31
21
186
6
55
1.09
0.09
2.0
1.2
—
—
—
0
0
6
55
1.09
0.09
1.0
1.0
—
—
—
0
0
5
60
0.83
0.08
1.2
1.6
2.64
2.73
mmol/l
—
5
44
5
63
0.79
0.08
1.2
1.0
—
—
—
0
0
7
64
1.10
0.08
2.7
3.1
7.17
7.53
mmol/l
—
7
64
7
64
1.10
0.08
2.6
1.8
—
—
—
0
0
6
72
0.83
0.07
1.8
2.6
26.82
24.63
mmol/l
—
6
72
8
78
1.03
0.07
1.3
1.1
—
—
—
0
0
13
118
1.10
0.07
1.7
1.4
—
—
—
0
0
13
118
1.10
0.07
1.6
1.4
—
—
—
0
0
97
992
0.97
0.07
3.1
2.9
—
—
—
0
0
18
193
0.93
0.06
2.7
2.4
—
—
—
0
0
10
90
1.11
0.05
1.4
2.2
—
—
—
0
0
31
298
1.04
0.04
1.1
1.2
98.11
178.99
iu/ml
—
9
136
10
108
0.92
0.03
1.4
1.3
—
—
—
0
0
13
122
1.07
0.02
1.6
1.5
—
—
—
0
0
31
318
0.97
0.02
1.3
1.4
—
—
—
0
0
70
691
1.02
0.02
1.7
1.6
—
—
—
0
0
47
471
1.00
0.00
1.6
1.4
—
—
—
0
0
15
146
1.03
0.00
17.3
4.7
—
—
—
0
0
6
60
1.00
0.00
1.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
2.18
—
0
5
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.1
—
16.56
—
0
16
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
3.54
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
12.5
—
45.50
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
34.26
—
0
5
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0
8
79
1.01
-0.00
4.1
3.8
27.55
114.58
mg/l
—
8
62
0
7
0.00
-0.00
0.0
3.0
—
—
—
0
0
8
79
1.01
-0.00
4.1
3.8
35.32
29.25
mg/l
—
8
60
13
130
1.00
-0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
1.1
1.5
—
—
—
0
0
8
79
1.01
-0.00
1.3
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_ABNAUDPER and mortality.

Females

Parameter HR [95% CI] p-value
H8_ABNAUDPER 0.748 [0.58, 0.96] 0.025
Birth year 0.998 [0.99, 1.01] 0.628

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 1328 females with H8_ABNAUDPER died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H8_ABNAUDPER.

N-year risk Females Males
1 0.074% No data
5 0.432% No data
10 1.122% No data
15 2.294% No data
20 4.246% No data

Relationships between endpoints

Index endpoint: H8_ABNAUDPER – Other abnormal auditory perceptions

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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