Cutaneous autosensitization

L12_CUT_AUTOSENS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L30.2 Cause of death: ICD-10 — L30.2 2 out of 7 registries used, show all original rules.	53
4. Check minimum number of events None	53
5. Include endpoints None	53
6. Filter based on genotype QC (FinnGen only)	51

Control definitions (FinnGen only)

Control exclude: L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L30
Name in latin: Reactio "id"

NAME	L12_CUT_AUTOSENS
CONTROL_EXCLUDE	L12_DERMATITISECZEMA
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L302
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L302
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Cutaneous autosensitization based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	378	203	172
Only index persons	355	197	158
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	45.42	45.51	45.03
Only index persons	45.42	46.08	44.60

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	51	32	19
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	49.38	49.61	49.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
53: Matched controls
530

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L30.2

ICD-10 Finland

Cutaneous autosensitization

+∞

75.9

L30.9

ICD-10 Finland

Dermatitis, unspecified

23.3

31.5

D07AC13

ATC

mometasone; topical

9.7

15.9

L30.3

ICD-10 Finland

Infective dermatitis

48.6

14.6

E0000UV, ,

ATC

9.2

13.7

123

D07AC01

ATC

betamethasone; topical

7.8

12.7

XQ802

NOMESCO Finland

Epicutan test

84.1

12.2

D07AD01

ATC

clobetasol; topical

11.7

11.2

L20.0

ICD-10 Finland

Besnier prurigo

+∞

9.7

Z01.5

ICD-10 Finland

Diagnostic skin and sensitization tests

12.6

8.5

B86

ICD-10 Finland

Scabies

92.5

7.6

D02AE01

ATC

carbamide; topical

19.3

7.6

B35.3

ICD-10 Finland

Tinea pedis

24.1

7.4

D07AB08

ATC

desonide; topical

7.5

6.0

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3000494) Fungus identified in Specimen by Culture

3.86

3.36

1.8

1.4

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

7.73

2.60

1.4

1.0

—

(40768443) Skin Pathology biopsy report

7.73

2.60

1.4

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.56

2.51

2.1

1.8

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

4.36

2.10

5.7

3.8

0.48

0.80

—

(3022217) INR in Platelet poor plasma by Coagulation assay

152

2.22

2.07

9.1

8.9

1.20

1.14

inr

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

4.09

1.99

5.7

3.7

1.68

2.46

—

(3014007) Fractional oxyhemoglobin in Arterial blood

4.09

1.99

5.7

3.7

94.85

90.57

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

4.89

1.98

1.2

1.6

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.50

1.90

2.6

2.3

0.69

0.41

e6/l

—

(3023368) Bacteria identified in Blood by Culture

2.33

1.90

4.3

3.8

—

(40760892) CBC W Ordered Manual Differential panel - Blood

202

2.12

1.88

7.1

5.6

—

(3021960) Folate [Moles/volume] in Serum or Plasma

2.36

1.79

1.1

1.5

18.73

20.65

nmol/l

0.29

(3007853) Bacteria identified in Skin by Aerobe culture

2.46

1.64

1.5

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

139

2.00

1.57

2.0

2.8

7.65

20.73

ng/l

3.54

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

139

2.00

1.57

2.0

1.7

107.32

100.65

pmol/l

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

3.09

1.55

1.0

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

3.34

1.47

1.4

1.1

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

2.07

1.41

1.5

1.2

1.05

0.58

u/ml

—

(40761535) Cells panel - Urine sediment

2.59

1.36

2.1

3.7

—

(3022096) Basophils/100 leukocytes in Blood

191

1.84

1.33

7.3

5.0

0.55

0.69

0.77

173

(3019060) Gas panel - Arterial blood

2.95

1.31

13.2

6.5

—

(3018010) Neutrophils/100 leukocytes in Blood

202

1.82

1.28

6.8

4.7

57.01

56.97

0.01

186

(3013826) Glucose [Moles/volume] in Serum or Plasma

223

1.80

1.23

6.7

4.0

6.78

6.63

mmol/l

0.15

197

(3044640) Blood type and Crossmatch panel - Blood

132

1.83

1.21

2.3

1.8

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

132

1.83

1.21

3.0

2.4

—

(3002030) Lymphocytes/100 leukocytes in Blood

205

1.78

1.20

7.1

5.0

29.29

28.50

0.16

190

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

2.02

1.16

1.7

1.2

1.03

17.00

u/ml

—

(3006504) Eosinophils/100 leukocytes in Blood

197

1.76

1.16

7.3

4.9

2.87

2.65

0.18

179

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.52

1.11

1.6

1.9

—

(3023520) Reticulocytes [#/volume] in Blood

2.52

1.11

1.0

3.3

87.00

79.55

e9/l

—

(3019069) Monocytes/100 leukocytes in Blood

199

1.73

1.11

7.4

5.2

8.10

8.23

0.09

184

(3042936) Bacteria identified in Isolate by Culture

2.05

1.05

1.6

—

(40768804) Tissue Pathology biopsy report

157

1.69

0.99

2.2

1.8

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

384

1.86

0.98

5.2

4.6

1.92

1.80

mu/l

0.25

355

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.20

0.92

2.2

1.9

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.82

0.85

4.0

3.0

0.84

0.81

mmol/l

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

1.75

0.75

4.6

2.7

28.50

227.62

ng/l

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.94

0.70

5.6

2.9

2.51

1.33

mmol/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.63

0.68

2.3

2.2

—

(4200892) Spirometry reversibility

1.87

0.68

1.0

1.4

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

319

1.53

0.65

4.2

14.14

14.64

pmol/l

0.63

291

(3019225) pH of Specimen

1.80

0.65

2.6

4.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

406

1.72

0.64

13.4

9.2

90.26

86.42

ml/min/173m2

0.90

329

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.63

0.63

3.5

2.2

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.62

0.0

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.62

0.0

1.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.62

0.0

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.62

0.0

1.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

280

1.47

0.62

4.9

4.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.61

0.0

1.5

—

(36660697) Celiac disease serology panel - Serum

1.86

0.61

1.2

1.1

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.61

0.0

1.6

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.61

0.0

1.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.80

0.60

1.5

2.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.75

0.59

1.5

2.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.54

0.57

3.6

2.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.61

0.55

2.8

2.1

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.53

0.55

4.4

3.7

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.56

0.53

6.0

4.7

103.83

104.40

mmol/l

—

(36304419) Bacteria [Presence] in Urine

103

1.49

0.52

2.6

2.3

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.53

0.49

1.4

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.50

0.45

1.4

2.2

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

427

1.58

0.45

18.1

11.6

139.48

139.70

mmol/l

0.22

421

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

191

1.36

0.44

2.9

2.3

—

(3003694) ABO and Rh group [Type] in Blood

125

1.40

0.44

1.2

1.6

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.62

0.43

1.2

1.3

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.42

0.0

3.3

—

15.10

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.42

0.0

1.7

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.40

0.0

1.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.40

0.0

1.4

—

(3033658) Prothrombin time (PT) actual/Normal

1.43

0.40

7.6

2.7

96.92

98.97

0.11

(3026008) Bacteria identified in Urine by Culture

109

1.39

0.38

2.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

304

1.33

0.38

4.3

3.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.65

0.36

2.7

1.8

—

(3000492) Spirometry study

1.44

0.36

1.3

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.38

0.35

4.0

5.7

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

431

1.51

0.34

18.1

11.6

3.89

3.97

mmol/l

1.12

424

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.37

0.32

1.6

1.5

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

459

1.48

0.28

17.5

12.2

69.56

72.99

umol/l

1.49

459

(3010813) Leukocytes [#/volume] in Blood

491

0.76

0.23

28.8

16.6

7.14

6.63

e9/l

0.79

481

(3026361) Erythrocytes [#/volume] in Blood

491

0.76

0.23

28.6

16.5

4.58

4.55

e12/l

0.19

480

(3007461) Platelets [#/volume] in Blood

490

0.78

0.23

28.5

16.5

267.83

252.76

e9/l

0.69

483

(3044889) 12 lead EKG panel

286

0.82

0.23

2.7

3.1

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.21

0.0

1.4

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.21

0.0

4.4

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.21

0.0

1.1

—

(3048689) Calprotectin [Mass/mass] in Stool

1.17

0.18

1.9

212.71

76.06

ug/g

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

159

1.20

0.18

3.7

3.2

—

(40761511) CBC panel - Blood by Automated count

458

0.88

0.17

17.9

10.5

—

(3013512) EKG study

117

0.82

0.15

2.7

3.0

—

(3041096) Erythrocytes [Presence] in Urine by Automated

115

0.84

0.12

2.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.82

0.07

1.7

1.4

—

(1761868) Lipid panel - Serum or Plasma

168

0.93

0.03

1.8

2.3

—

(40758558) Short blood count panel - Blood

116

1.04

0.00

10.8

5.6

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.5

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

1.7

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.02

-0.00

1.7

1.9

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.8

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.2

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

-0.00

0.0

2.2

—

39.34

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

253.86

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

2.4

—

477.20

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.3

—

1.57

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.2

—

4.23

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

5.4

—

2.02

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.2

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(1616796) Gas panel - Central venous blood

0.00

-0.00

0.0

1.6

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

965.20

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

4.0

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.4

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.2

—

105.17

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.3

—

10.37

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.98

-0.00

1.4

2.1

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

-0.00

0.0

2.7

—

(3024980) IgG subclass 4 [Mass/volume] in Serum

0.00

-0.00

0.0

1.4

—

0.69

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

3.6

—

57.60

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

222.00

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.4

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.3

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_CUT_AUTOSENS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_CUT_AUTOSENS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_CUT_AUTOSENS – Cutaneous autosensitization

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Cutaneous autosensitization

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints