skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
423 |
4. Check minimum number of eventsNone |
423 |
5. Include endpointsNone |
423 |
6. Filter based on genotype QC (FinnGen only) |
399 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L90
- Name in latin
- Striae atrophicae
Similar endpoints
↥List of similar endpoints to
Striae atrophicae
based on the number of shared cases.
Similar with more cases:
- Atrophic disorders of skin
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2553 | 1773 | 764 |
| Only index persons | 2451 | 1722 | 729 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.02 |
| Only index persons | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 34.96 | 37.84 | 28.31 |
| Only index persons | 35.09 | 37.92 | 28.41 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 399 | 321 | 78 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.04 |
| Median age at first event (years) | 43.74 | 43.67 | 44.02 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 423
- Matched controls
- 4230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L90.6
ICD-10 Finland
Striae atrophicae
4503599627370496.0
307.7
417
*
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
57.9
89.6
51
10
QBJ30
NOMESCO Finland
Correction of abdominal apron
36.7
67.8
43
13
ZZF00
NOMESCO Finland
Graft of adipose tissue
29.5
66.2
45
17
ZXE10
NOMESCO Finland
More than one and less than three hours
5.0
60.2
253
964
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
160.8
54.3
56
*
ZXE00
NOMESCO Finland
One hour or less
4.5
50.4
272
1204
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
171.5
44.8
46
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
8.9
41.4
55
70
WX408
NOMESCO Finland
General anesthesy, balanced
4.0
41.4
180
664
L91.0
ICD-10 Finland
Hypertrophic scar
71.6
40.0
45
7
ZXE20
NOMESCO Finland
More than three and less than five hours
4.9
39.3
104
264
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
6.8
38.1
65
110
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.8
36.3
158
575
ZXD10
NOMESCO Finland
Scheduled procedure
3.4
33.6
223
1050
Z3226
NOMESCO Finland
Physiotherapist
3.8
31.7
128
438
R4110
NOMESCO Finland
Physiotherapy
3.3
30.8
169
702
QBJ00
NOMESCO Finland
Liposuction in trunk
52.6
28.9
34
7
ZZA00
NOMESCO Finland
Split skin graft
27.9
26.6
36
14
Z3231
NOMESCO Finland
Registered nurse
3.1
26.3
164
723
WX402
NOMESCO Finland
General anaesthesia
3.2
25.5
138
559
X59
ICD-10 Finland
Exposure to unspecified factor
3.3
25.4
124
472
ZXD05
NOMESCO Finland
Urgent procedure
2.8
23.6
186
920
R4120
NOMESCO Finland
Occupational therapy
4.7
22.9
57
135
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
5.6
22.5
45
88
Z2221
NOMESCO Finland
Medical doctor
2.8
22.2
172
838
WX002
NOMESCO Finland
Sedation and analgesia
3.1
21.4
110
428
N62
ICD-10 Finland
Hypertrophy of breast
5.2
21.1
46
97
ZXA10
NOMESCO Finland
Bilateral
3.1
20.9
105
402
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.6
20.6
76
240
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.5
19.8
52
128
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.5
19.0
49
119
TQW99
NOMESCO Finland
Other minor procedure on skin
5.5
18.2
37
73
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
3.9
18.2
58
165
J01FF01
ATC
clindamycin; systemic
2.6
17.4
142
696
ZXA05
NOMESCO Finland
Left side
2.7
17.1
119
539
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
16.8
150
764
QCE20
NOMESCO Finland
Excision and repair of scar or web of skin of upper limb
176.7
16.6
17
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.4
16.6
44
109
TQW40
NOMESCO Finland
Remowal of suture of skin
4.1
16.4
48
128
N03AX16
ATC
[U] pregabalin
2.6
16.4
120
555
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
16.3
72
253
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.0
16.0
49
135
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
15.6
187
1077
N02AX02
ATC
tramadol; systemic, rectal
2.3
15.5
196
1154
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
39.7
15.5
19
5
WX110
NOMESCO Finland
Infiltration anesthesia
2.7
14.6
346
2634
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.0
14.3
26
46
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.6
13.8
34
79
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
13.7
89
385
TKC20
NOMESCO Finland
Catheterisation of bladder
4.3
13.4
36
90
E0000UV, ,
ATC
2.1
13.3
206
1296
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
15.7
13.2
21
14
Z2446
NOMESCO Finland
Social worker
3.6
13.0
46
140
S29
ICPC
Skin symptom/complaint other
2.5
13.0
97
449
S18
ICPC
Laceration/cut
2.1
12.9
199
1246
HA1AA
NOMESCO Finland
X-ray mammography
3.2
12.3
52
177
P01AB01
ATC
metronidazole; oral, rectal
2.1
12.3
203
1297
ZXD35
NOMESCO Finland
Usual procedure
5.7
12.2
23
42
SXC05
NOMESCO Finland
Other oral or dental procedure
3.2
12.1
50
168
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.0
11.8
26
55
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.1
11.8
207
1346
A46
ICD-10 Finland
Erysipelas
2.9
11.7
58
217
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
11.4
173
1064
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.7
11.3
37
107
H02AB06
ATC
prednisolone; systemic
2.0
11.2
207
1363
ZZR00
NOMESCO Finland
Flap of skin
11.6
11.2
20
18
N06AB04
ATC
citalopram; systemic
2.3
11.1
107
550
XKD03
NOMESCO Finland
Urethral pressure profilometry
5.9
11.1
20
35
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.3
11.1
29
71
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
11.0
62
248
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
10.0
10.9
21
22
XKD00
NOMESCO Finland
Uroflowmetry
3.3
10.8
43
141
QDE20
NOMESCO Finland
Excision and repair of scar or web of skin of lower limb
61.6
10.7
12
*
J01MA12
ATC
levofloxacin; systemic
2.5
10.7
78
355
N02BE01
ATC
paracetamol; systemic, rectal
3.2
10.6
389
3300
N05BA04
ATC
oxazepam; oral
2.1
10.6
133
759
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
12.5
10.4
18
15
M79.6
ICD-10 Finland
Pain in limb
2.0
10.4
197
1300
N05CF01
ATC
zopiclone; oral
2.0
10.3
142
837
N06AX16
ATC
venlafaxine; oral
2.3
10.2
89
438
B01AB05
ATC
enoxaparin; parenteral
2.1
10.2
132
760
SAA04
NOMESCO Finland
Special examination of mouth
3.3
10.2
39
125
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
10.1
118
653
L28
ICPC
Limited function/disability (L)
2.5
10.0
70
311
J01DB01
ATC
cefalexin; oral
2.6
10.0
369
3074
UKC02
NOMESCO Finland
Cystoscopy
2.8
9.9
55
218
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
13.8
9.7
16
12
TQW20
NOMESCO Finland
Tatoe
10.4
9.6
18
18
X58
ICD-10 Finland
Exposure to other specified factors
2.4
9.6
76
358
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
9.6
98
514
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.4
9.6
73
338
Z71.8
ICD-10 Finland
Other specified counselling
1.9
9.5
160
1007
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.3
9.4
19
37
HAE99
NOMESCO Finland
Other reconstruction of breast
11.0
9.4
17
16
R52.2
ICD-10 Finland
Other chronic pain
3.9
9.0
27
73
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.1
8.9
38
130
A02BC02
ATC
pantoprazole; systemic
1.9
8.8
278
2122
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
8.8
64
290
A02BC05
ATC
esomeprazole; systemic
1.9
8.7
178
1186
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.4
8.7
32
100
N06AX26
ATC
vortioxetine; oral
2.7
8.6
49
197
N03AE01
ATC
clonazepam; systemic
3.3
8.6
33
106
D07AD01
ATC
clobetasol; topical
2.3
8.5
74
362
L70.0
ICD-10 Finland
Acne vulgaris
3.9
8.5
25
67
J01MA02
ATC
ciprofloxacin; systemic
1.9
8.5
148
936
N06AX22
ATC
agomelatine; oral
4.6
8.5
20
45
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
8.1
8.4
18
23
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.4
8.4
64
295
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
5.0
8.4
18
37
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.5
8.4
29
87
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
8.4
176
1179
J01DA01
ATC
[U] cefalexin
1.9
8.3
272
2083
E66.8
ICD-10 Finland
Other obesity
2.9
8.3
39
141
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
7.8
8.2
18
24
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.5
8.2
20
46
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.5
8.2
28
83
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
8.2
42
160
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
8.2
62
286
R03DC03
ATC
montelukast; oral
2.1
8.0
89
479
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.6
8.0
50
210
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
8.0
89
480
E03.89
ICD-10 Finland
Other specified hypothyroidism
4.1
8.0
22
56
JN3AD
NOMESCO Finland
Abdominal CT examination
2.5
8.0
51
217
Z01.2
ICD-10 Finland
Dental examination
1.8
8.0
217
1565
A01
ICPC
Pain general/multiple sites
2.5
7.9
50
212
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
7.9
64
304
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
7.9
152
988
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.7
7.8
25
71
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.6
7.8
26
76
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.9
7.8
37
135
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.6
7.7
45
183
A02BC01
ATC
omeprazole; systemic
1.9
7.7
117
703
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.7
7.7
24
67
N30.9
ICD-10 Finland
Cystitis, unspecified
2.9
7.7
37
136
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.1
7.6
33
114
AA1AD
NOMESCO Finland
CT of head and brain
2.0
7.6
96
541
N06AX11
ATC
mirtazapine; oral
1.8
7.6
154
1014
ZXA00
NOMESCO Finland
Right side
2.0
7.5
103
597
A06AD11
ATC
lactulose; oral
2.4
7.5
53
236
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
7.5
41
161
A99
ICPC
Disease/condition unspecnature/site
2.7
7.5
41
161
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.4
7.5
27
83
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.0
7.5
33
115
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
7.5
51
224
N05BA01
ATC
diazepam; systemic, rectal
2.2
7.4
64
311
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.9
7.4
35
127
R01AD12
ATC
fluticasone furoate; nasal
1.8
7.4
162
1090
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.6
7.4
43
175
S06.0
ICD-10 Finland
Concussion
2.4
7.4
54
245
E000001, ,
ATC
2.0
7.3
101
586
ZXD20
NOMESCO Finland
Day surgery
2.2
7.3
64
314
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
3.7
7.2
23
65
Z50.1
ICD-10 Finland
Other physical therapy
3.5
7.2
25
75
E000002, ,
ATC
2.2
7.2
62
302
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
8.1
7.2
15
19
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
4.2
7.2
19
47
XKC03
NOMESCO Finland
Water cystometry
4.2
7.2
19
47
H02AB09
ATC
hydrocortisone; systemic
5.8
7.1
19
34
C03CA01
ATC
furosemide; systemic
2.1
7.1
79
424
R03AC02
ATC
salbutamol; inhalant
1.7
7.1
257
1986
D07AC01
ATC
betamethasone; topical
1.8
7.1
149
988
A08
ICPC
Swelling
3.1
7.1
29
97
S01.1
ICD-10 Finland
Open wound of eyelid and periocular area
4.5
7.0
17
39
N06AB10
ATC
escitalopram; oral
1.9
7.0
116
714
J01MA06
ATC
norfloxacin; oral
2.2
7.0
62
305
L05
ICPC
Flank/axilla symptom/complaint
2.9
7.0
33
120
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
3.4
6.9
25
77
B03BA03
ATC
hydroxocobalamin; parenteral
3.6
6.9
23
67
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
6.9
105
628
J45
ICD-10 Finland
Asthma
2.3
6.9
53
246
GBB00
NOMESCO Finland
Tracheostomy
11.2
6.8
12
11
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
5.8
6.8
18
32
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.3
6.8
25
78
N05AH04
ATC
quetiapine; oral
1.9
6.8
95
553
QDE30
NOMESCO Finland
Excision and repair of surgical scar in lower limb
40.7
6.8
8
*
S21
ICPC
Skin texture symptom/complaint
2.2
6.8
64
323
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.8
6.8
114
705
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.3
6.7
51
235
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
22.9
6.7
9
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
6.7
184
1311
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.3
6.7
53
249
R05
ICD-10 Finland
Cough
1.9
6.7
98
580
R33
ICD-10 Finland
Retention of urine
3.5
6.6
23
69
WX730
NOMESCO Finland
Conventional respirator
12.5
6.6
11
9
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
6.6
69
362
R53
ICD-10 Finland
Malaise and fatigue
1.9
6.6
107
654
R03BA02
ATC
budesonide; inhalant
1.9
6.6
88
505
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
6.6
37
148
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.4
6.5
47
211
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
6.5
115
720
R60.0
ICD-10 Finland
Localized oedema
2.4
6.5
46
205
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.4
6.5
23
70
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.8
6.5
32
119
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.8
6.5
32
119
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.6
6.5
37
149
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.1
6.4
67
352
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
6.4
44
194
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
6.4
41
175
TQW11
NOMESCO Finland
Vacuum treatment of wound
6.1
6.4
16
27
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
6.4
186
1343
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.1
6.4
64
331
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
3.1
6.3
26
87
ZZR10
NOMESCO Finland
Flap of skin and muscle
9.5
6.3
12
13
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.8
6.3
32
121
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.2
6.3
25
82
F50.9
ICD-10 Finland
Eating disorder, unspecified
7.2
6.3
14
20
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.2
6.3
24
77
QBA00
NOMESCO Finland
Puncture of skin of trunk
+∞
6.3
6
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
6.2
94
560
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.3
6.2
46
210
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.0
6.2
27
94
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.4
6.1
41
178
R22.4
ICD-10 Finland
Localized swelling, mass and lump, lower limb
4.2
6.1
16
39
M54.8
ICD-10 Finland
Other dorsalgia
2.9
6.1
28
100
L02BA01
ATC
tamoxifen; oral
3.0
6.1
26
89
TQB05
NOMESCO Finland
Puncture of skin of trunk
10.2
6.1
11
11
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.9
6.0
81
464
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
89
298
3.52
22.15
4.1
2.8
—
—
—
0
0
216
1246
2.50
18.94
6.2
4.1
36.43
36.62
g/l
0.21
202
1168
33
70
5.03
14.97
2.8
1.6
—
—
—
0
0
81
333
2.77
13.79
6.2
4.8
1.07
1.03
mmol/l
0.60
74
308
92
406
2.62
13.61
2.6
2.1
2.48
2.43
g/l
0.40
82
378
177
1049
2.18
13.29
4.6
2.9
2.34
2.35
mmol/l
0.46
159
942
99
460
2.50
13.12
3.3
3.1
0.84
0.82
mmol/l
0.65
87
436
139
761
2.23
12.60
2.6
2.1
2.67
2.86
mg/l
0.66
124
648
83
373
2.52
11.72
2.8
2.2
23.61
23.87
%
0.06
73
320
117
616
2.24
11.53
3.6
2.2
8.03
7.57
e6/l
0.08
107
561
93
445
2.40
11.44
2.6
2.1
14.54
14.24
umol/l
0.14
84
412
257
1838
2.01
10.89
4.9
4.2
6.20
6.39
mmol/l
0.91
244
1671
57
220
2.84
10.83
5.2
3.3
1.23
1.23
mmol/l
0.24
49
184
101
514
2.27
10.72
3.0
2.4
2.43
2.43
mmol/l
0.04
87
453
236
1652
1.97
10.48
7.1
5.4
9.08
10.25
umol/l
1.86
224
1563
239
1684
1.96
10.37
6.9
5.5
29.82
29.17
%
0.43
227
1596
141
831
2.05
10.21
4.3
2.6
0.22
0.34
e6/l
1.00
108
622
270
2002
1.96
9.87
9.5
8.6
4.02
4.01
e9/l
0.01
242
1759
235
1673
1.91
9.61
6.5
5.3
56.11
56.68
%
0.34
225
1583
168
1073
1.94
9.54
4.4
2.8
—
—
—
0
0
322
2555
2.09
9.51
9.7
6.6
74.30
73.98
u/l
0.05
306
2389
92
476
2.19
9.27
2.2
1.6
1362.22
1134.65
nmol/l
1.48
73
364
179
1181
1.89
9.11
2.0
1.8
99.01
98.21
pmol/l
0.08
97
601
241
1766
1.85
8.64
3.9
2.7
123.24
84.51
ug/l
0.56
226
1657
180
1215
1.84
8.34
12.1
9.0
1.11
1.13
inr
0.11
80
383
19
42
4.69
8.20
3.2
1.9
17.59
15.91
%
—
8
18
141
887
1.88
8.13
1.6
1.6
1.42
1.37
mmol/l
0.35
115
774
190
1322
1.79
7.84
6.7
5.3
1.22
1.22
mmol/l
0.21
174
1221
205
1459
1.79
7.83
7.3
6.0
1.21
1.22
mmol/l
0.57
164
1256
59
279
2.30
7.31
1.5
1.3
26.30
25.34
iu/l
0.07
49
239
46
198
2.48
7.02
1.6
1.5
—
—
—
0
0
342
2887
1.96
6.95
5.5
4.0
14.49
14.50
pmol/l
0.01
318
2662
60
294
2.21
6.83
2.3
2.2
29.38
32.19
u/l
0.28
53
243
376
3308
2.23
6.46
16.2
9.6
90.65
89.36
ml/min/173m2
0.54
331
2667
196
1448
1.66
6.05
3.0
2.3
73.98
75.16
nmol/l
0.24
182
1323
364
3202
1.98
5.67
22.5
13.3
13.80
14.36
%
2.40
359
3148
120
791
1.72
5.61
2.0
1.7
1.20
0.94
mg/l
0.43
83
598
11
13
8.65
5.59
1.3
1.4
68.73
60.54
nmol/24h
0.21
11
13
377
3364
2.11
5.54
6.3
4.7
1.68
1.78
mu/l
1.02
365
3135
103
653
1.76
5.52
1.7
1.5
20.14
21.50
nmol/l
0.50
92
570
395
3592
2.51
5.51
18.8
10.8
20.73
19.93
mg/l
0.20
328
2717
44
209
2.23
5.40
3.6
3.7
80.34
69.44
ng/l
0.52
35
189
215
1659
1.60
5.35
3.2
2.4
—
—
—
0
0
139
965
1.66
5.31
1.5
1.3
1.01
2.11
u/ml
0.78
35
261
388
3519
2.24
5.15
18.9
11.4
3.91
3.92
mmol/l
0.71
378
3401
387
3510
2.21
5.08
18.8
11.4
139.56
139.63
mmol/l
0.25
379
3403
85
524
1.78
4.98
3.4
3.1
248.40
294.11
ng/l
0.07
57
328
296
2502
1.61
4.74
3.9
2.9
43.69
39.14
u/l
0.55
271
2365
160
1184
1.57
4.57
4.3
2.9
45.89
29.87
u/l
0.48
154
1131
17
55
3.18
4.41
3.6
3.3
61.94
56.29
%
0.93
17
55
44
228
2.04
4.35
3.6
3.3
2.32
1.89
mmol/l
0.38
38
180
115
799
1.60
4.26
2.7
2.0
—
—
—
0
0
121
853
1.59
4.21
2.8
2.0
147.85
228.37
u/l
0.51
113
809
63
375
1.80
4.13
3.5
2.4
5.08
6.67
umol/l
0.91
58
321
216
1736
1.50
4.07
4.4
3.2
0.00
0.00
estimate
0.50
70
355
55
316
1.85
4.04
5.6
6.1
104.78
104.43
mmol/l
0.20
55
316
16
54
3.04
3.89
3.5
3.3
4.60
4.35
e9/l
0.13
16
54
214
1734
1.47
3.78
6.1
4.5
0.00
0.00
estimate
0.50
69
332
13
34
3.91
3.72
3.9
1.7
1.85
1.73
mmol/l
0.17
13
34
72
463
1.67
3.59
3.7
2.6
3.52
3.29
e6/l
0.06
37
238
16
57
2.88
3.56
1.3
1.9
134.50
131.65
g/l
—
10
37
25
112
2.31
3.55
1.4
1.3
—
—
—
0
0
215
1758
1.45
3.54
4.4
3.3
0.00
0.00
estimate
-0.00
66
324
89
606
1.59
3.53
2.5
1.7
474.62
426.75
pmol/l
1.14
73
526
17
63
2.77
3.53
5.8
3.0
42.12
30.20
u/ml
0.23
17
63
11
27
4.15
3.42
1.5
1.4
60.40
53.14
%
—
5
21
13
42
3.16
3.40
1.2
1.4
—
—
—
0
0
401
3775
2.20
3.34
12.9
8.7
27.62
25.50
u/l
0.46
392
3648
74
488
1.63
3.34
3.7
2.4
1.00
0.90
e6/l
0.15
39
261
13
43
3.09
3.28
2.0
1.5
—
—
—
0
0
24
110
2.25
3.25
1.3
1.1
—
—
—
0
0
15
55
2.79
3.18
1.6
5.5
24.63
27.36
mg/l
—
7
45
127
954
1.47
3.18
1.7
1.6
—
—
—
0
0
294
2581
1.46
3.13
5.4
3.7
11.53
9.81
mm/h
1.23
271
2387
35
189
1.93
3.12
1.8
2.7
67.05
67.26
g/l
0.06
35
176
131
996
1.46
3.07
3.2
2.3
60.61
56.26
u/l
0.37
123
922
17
69
2.53
2.99
1.2
1.1
—
—
—
0
0
120
904
1.46
2.94
4.4
2.9
7.33
7.64
mmol/l
0.29
102
781
338
3064
1.51
2.93
5.2
4.6
37.63
38.45
mmol/mol
1.04
323
2882
42
246
1.79
2.93
1.1
1.0
—
—
—
0
0
27
136
2.05
2.92
1.3
1.3
12.97
10.61
u/l
0.30
21
109
15
58
2.64
2.90
1.2
1.2
3.33
4.85
u/ml
—
6
26
135
1042
1.43
2.90
3.0
3.1
34.01
38.22
ng/l
0.08
73
581
7
13
5.46
2.88
2.1
1.5
23.71
27.54
umol/l
—
7
13
8
18
4.51
2.80
2.1
2.7
589.13
390.61
u/ml
—
8
18
36
204
1.84
2.79
1.5
1.6
239.03
278.85
mu/l
0.71
29
181
9
23
3.97
2.79
1.1
1.0
—
—
—
0
0
15
60
2.56
2.73
1.8
1.3
—
—
—
0
0
15
60
2.56
2.73
1.8
1.3
—
—
—
0
0
14
55
2.60
2.64
1.6
5.5
22.72
38.88
mg/l
—
6
46
10
30
3.39
2.62
1.3
2.5
3.06
4.02
nmol/l
—
10
30
27
144
1.93
2.52
2.0
1.8
—
—
—
0
0
313
2826
1.41
2.50
3.9
3.6
—
—
—
0
0
8
21
3.86
2.47
1.4
1.7
—
—
—
0
0
52
340
1.60
2.45
1.2
1.2
171.71
157.47
iu/ml
0.07
15
152
47
300
1.64
2.43
2.2
1.7
—
—
—
0
0
14
58
2.46
2.39
1.1
1.0
—
—
—
0
0
12
274
0.42
2.38
1.3
1.5
—
—
—
0
0
8
22
3.69
2.37
1.1
1.2
—
—
—
0
0
11
39
2.87
2.36
1.1
1.3
—
—
—
0
0
30
171
1.81
2.31
1.7
1.4
—
—
—
0
0
13
53
2.50
2.30
1.6
5.4
—
3.64
—
0
6
46
297
1.62
2.28
2.1
1.7
—
—
—
0
0
15
68
2.25
2.13
1.1
1.1
—
—
—
0
0
26
147
1.82
2.07
2.2
3.3
2.60
1.70
mmol/l
0.64
17
110
15
69
2.22
2.07
1.3
1.4
105.55
114.53
u/ml
—
6
15
61
432
1.48
2.03
2.2
1.7
—
—
—
0
0
43
282
1.58
2.02
2.0
2.2
3098.04
2981.82
u/l
—
7
125
10
38
2.67
2.01
1.8
2.2
—
—
—
0
0
18
91
2.02
1.98
1.6
2.3
—
—
—
0
0
14
64
2.23
1.96
1.7
1.3
—
—
—
0
0
5
12
4.20
1.83
1.4
2.9
61.60
113.08
nmol/l
—
5
12
16
81
2.01
1.77
1.3
1.2
—
—
—
0
0
114
922
1.32
1.75
4.9
3.4
0.00
0.00
estimate
0.50
68
334
21
119
1.80
1.69
1.3
1.1
—
—
—
0
0
10
40
2.54
1.67
2.0
1.4
—
—
—
0
0
23
135
1.74
1.66
1.1
1.3
—
—
—
0
0
17
91
1.90
1.63
1.4
1.3
341.70
331.62
ug/g
—
10
52
27
168
1.65
1.59
2.4
2.0
7.36
11.88
nmol/l
1.57
21
153
69
525
1.38
1.57
2.3
1.8
1.56
1.37
%
1.35
59
476
6
21
2.88
1.51
1.2
1.4
—
—
—
0
0
9
37
2.46
1.48
1.2
1.1
—
—
—
0
0
9
38
2.40
1.46
1.1
1.4
—
—
—
0
0
5
16
3.15
1.44
1.0
1.4
—
—
—
0
0
353
3342
1.34
1.44
4.4
3.8
5.72
5.73
mmol/l
0.10
336
3092
366
3484
1.37
1.44
4.7
4.2
2.83
2.86
mmol/l
0.22
352
3271
20
118
1.73
1.44
1.4
1.1
—
—
—
0
0
22
134
1.68
1.42
1.6
1.6
—
—
—
0
0
7
29
2.44
1.39
1.1
1.4
—
—
—
0
0
38
267
1.46
1.36
7.8
8.5
0.48
1.24
mmol/l
0.72
30
212
413
4036
1.99
1.35
26.6
16.2
40.14
40.28
%
0.28
403
3827
95
779
1.28
1.31
2.0
2.4
320.66
7350.25
umol/l
3.78
85
695
8
35
2.31
1.27
1.5
1.5
—
—
—
0
0
24
155
1.58
1.26
8.8
8.2
94.84
94.29
%
0.25
24
155
37
263
1.45
1.26
4.3
4.0
3.46
24.22
ug/l
0.67
27
211
413
4041
1.93
1.25
26.5
16.3
4.48
4.51
e12/l
0.68
408
3945
15
85
1.79
1.24
1.7
2.0
8.60
10.67
mg/l
0.67
15
75
11
57
1.95
1.18
2.0
1.5
3168.60
21610.57
e6/l
—
5
42
5
20
2.52
1.15
1.6
1.3
2.20
10.41
u/field
—
5
13
20
127
1.60
1.13
2.6
2.6
0.65
0.68
%
0.10
20
127
80
654
1.28
1.13
3.1
3.0
843.66
904.76
ng/l
0.10
65
533
7
30
2.36
1.13
1.0
1.2
—
—
—
0
0
7
30
2.36
1.13
1.0
1.2
—
—
—
0
0
10
51
1.98
1.12
1.9
1.3
—
—
—
0
0
7
31
2.28
1.11
1.0
1.2
—
—
—
0
0
7
31
2.28
1.11
1.0
1.2
—
—
—
0
0
7
31
2.28
1.11
1.0
1.2
—
—
—
0
0
28
196
1.46
1.05
1.8
1.7
2.37
3.01
mg/l
0.40
22
141
62
765
0.78
1.04
2.9
3.4
1.02
1.02
kg/l
—
6
102
18
114
1.60
1.04
5.2
1.9
—
—
—
0
0
9
46
1.98
1.04
1.6
2.8
3.34
86.24
u/ml
—
9
46
15
91
1.67
1.02
2.0
2.3
3.81
4.93
umol/l
—
10
68
32
232
1.41
1.01
2.0
2.4
73.82
76.61
ml/min/173m2
0.18
11
100
29
398
0.71
1.00
1.4
1.5
—
—
—
0
0
5
23
2.19
0.98
1.2
1.5
—
—
—
0
0
5
23
2.19
0.98
1.6
1.8
0.84
0.96
g/l
—
5
23
12
69
1.76
0.97
1.4
1.5
—
—
—
0
0
152
1355
1.19
0.94
4.8
3.2
—
—
—
0
0
57
458
1.28
0.94
2.4
1.8
—
—
—
0
0
6
27
2.24
0.94
1.2
1.0
—
—
—
0
0
33
245
1.38
0.92
1.5
1.3
—
—
—
0
0
16
102
1.59
0.92
1.4
1.7
0.02
0.01
iu/ml
—
7
18
358
3447
1.25
0.90
4.3
3.8
4.72
4.78
mmol/l
0.49
347
3254
6
29
2.08
0.89
1.8
2.3
0.67
2.64
u/field
—
6
11
27
195
1.41
0.88
2.2
1.8
—
—
—
0
0
6
30
2.01
0.87
1.7
1.4
—
—
—
0
0
13
80
1.64
0.85
1.4
1.3
—
—
—
0
0
6
31
1.95
0.84
1.7
1.5
—
—
—
0
0
45
356
1.30
0.84
2.5
1.8
—
—
—
0
0
343
3296
1.21
0.83
3.9
3.4
1.24
1.24
mmol/l
0.08
325
3087
8
46
1.75
0.83
1.5
1.5
—
—
—
0
0
8
47
1.72
0.81
1.1
1.5
—
—
—
0
0
26
346
0.74
0.77
7.5
5.4
—
—
—
0
0
11
172
0.63
0.75
2.1
1.7
—
—
—
0
0
89
772
1.19
0.75
2.4
2.2
—
—
—
0
0
15
100
1.52
0.74
1.1
1.1
1.52
3.40
u/ml
—
9
48
81
698
1.20
0.73
2.4
2.0
—
—
—
0
0
16
229
0.69
0.73
1.4
1.5
—
—
—
0
0
12
77
1.57
0.69
1.0
1.2
—
—
—
0
0
11
69
1.61
0.69
1.5
1.5
—
—
—
0
0
5
93
0.53
0.67
1.2
1.5
9.26
22.32
u/l
—
5
79
354
3430
1.20
0.67
4.3
3.8
1.52
1.51
mmol/l
0.02
337
3227
30
235
1.30
0.63
2.2
2.3
21.18
41.68
u/ml
1.05
30
226
8
50
1.61
0.61
1.5
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
1719.60
—
0
20
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
8
53
1.52
0.58
1.4
2.2
—
—
—
0
0
6
35
1.72
0.58
1.3
1.1
—
—
—
0
0
16
216
0.73
0.55
1.3
1.4
—
—
—
0
0
16
216
0.73
0.55
1.3
1.4
—
—
—
0
0
6
38
1.59
0.54
1.0
1.6
—
—
—
0
0
9
61
1.49
0.54
2.3
2.5
—
—
—
0
0
16
215
0.73
0.54
1.3
1.4
—
—
—
0
0
16
215
0.73
0.54
1.3
1.4
—
—
—
0
0
23
179
1.30
0.52
1.3
1.4
245.68
250.33
miu/ml
0.02
14
95
13
180
0.71
0.52
1.1
1.4
—
—
—
0
0
88
789
1.15
0.51
6.3
3.7
10.19
9.80
mg/mmol
0.03
55
483
14
189
0.73
0.49
1.5
1.6
—
—
—
0
0
7
47
1.50
0.48
1.3
1.1
—
—
—
0
0
96
872
1.13
0.46
1.7
1.4
—
—
—
0
0
5
31
1.62
0.43
1.0
1.5
—
—
—
0
0
5
33
1.52
0.41
1.8
1.5
—
—
—
0
0
5
33
1.52
0.41
1.8
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
642.83
—
0
12
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
43.50
—
0
12
12
159
0.75
0.39
1.7
2.0
—
—
—
0
0
28
234
1.21
0.38
2.9
2.7
0.62
0.81
ug/l
0.79
18
125
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
36
415
0.86
0.36
1.5
1.5
—
—
—
0
0
12
91
1.33
0.34
1.3
1.4
1.88
3.00
ug/l
0.96
12
79
11
83
1.33
0.32
1.1
1.3
—
38.20
—
0
7
7
56
1.25
0.29
1.6
2.0
13.29
13.12
%
—
7
56
12
94
1.28
0.28
1.7
1.6
—
—
—
0
0
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
10.00
—
0
11
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.7
1.5
—
—
—
0
0
6
49
1.23
0.20
1.7
1.5
—
—
—
0
0
34
310
1.11
0.18
4.3
4.1
16.38
21.78
%
1.15
12
124
70
664
1.06
0.16
1.3
1.3
14.70
29.69
iu/ml
2.07
14
236
6
77
0.78
0.15
3.5
1.4
—
—
—
0
0
13
112
1.17
0.14
1.8
1.9
1.87
5.59
iu/l
—
6
42
9
106
0.85
0.13
2.2
1.6
—
—
—
0
0
5
45
1.11
0.10
1.6
1.4
—
—
—
0
0
13
145
0.89
0.09
1.2
1.5
—
—
—
0
0
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
10
112
0.89
0.07
2.2
1.8
—
—
—
0
0
18
168
1.07
0.06
1.4
1.4
—
—
—
0
0
64
632
1.01
0.01
1.4
1.3
1.82
12.15
u/ml
4.30
24
260
10
94
1.07
0.01
1.3
1.3
—
3.21
—
0
12
0
5
0.00
0.00
0.0
1.0
—
65.20
—
0
5
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
29.70
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
7
72
0.97
-0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_STRIAEATROPHICAE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_STRIAEATROPHICAE | 1.328 [1.01, 1.75] | 0.045 |
| Birth year | 0.996 [0.99, 1.0] | 0.317 |
During the follow-up period (1.1.1998 — 31.12.2019), 72 out of 1519 females with L12_STRIAEATROPHICAE died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have L12_STRIAEATROPHICAE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.137% | No data |
| 5 | 0.764% | No data |
| 10 | 1.961% | No data |
| 15 | 3.999% | No data |
| 20 | 7.169% | No data |
Relationships between endpoints
↥Index endpoint: L12_STRIAEATROPHICAE – Striae atrophicae
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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