Striae atrophicae

L12_STRIAEATROPHICAE

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L90.6
  • Hospital discharge: ICD-9 7013X
  • Hospital discharge: ICD-8 70120
  • Cause of death: ICD-10 L90.6
  • Cause of death: ICD-9 7013X
  • Cause of death: ICD-8 70120

2 out of 7 registries used, show all original rules.

399

4. Check minimum number of events

None

399

5. Include endpoints

None

399

6. Filter based on genotype QC (FinnGen only)

399

Control definitions (FinnGen only)

Control exclude
L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L90
Name in latin
Striae atrophicae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2553 1773 764
Only index persons 2451 1722 729
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.02
Only index persons 0.05 0.06 0.03
Median age at first event (years)
Whole population 34.96 37.84 28.31
Only index persons 35.09 37.92 28.41

-FinnGen-

Key figures

All Female Male
Number of individuals 399 316 83
Unadjusted period prevalence (%) 0.09 0.11 0.04
Median age at first event (years) 42.74 42.67 42.99

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
355
Matched controls
3548
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L90.6
ICD-10 Finland
Striae atrophicae
4503599627370496.0
323.0
350
*
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
138.2
46.0
48
*
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
+∞
43.6
41
*
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
50.0
36.9
44
10
ZZF00
NOMESCO Finland
Graft of adipose tissue
84.5
34.6
38
5
WX408
NOMESCO Finland
General anesthesy, balanced
4.2
30.8
153
546
QBJ00
NOMESCO Finland
Liposuction in trunk
108.9
28.1
30
*
L91.0
ICD-10 Finland
Hypertrophic scar
58.3
27.7
32
6
QBJ30
NOMESCO Finland
Correction of abdominal apron
28.4
26.8
36
14
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.7
24.1
129
471
ZZA00
NOMESCO Finland
Split skin graft
22.5
21.7
31
15
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
6.8
21.4
56
95
R4110
NOMESCO Finland
Physiotherapy
3.3
21.3
133
539
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
9.7
20.0
41
47
R4120
NOMESCO Finland
Occupational therapy
6.1
17.4
49
91
X59
ICD-10 Finland
Exposure to unspecified factor
3.3
16.7
95
350
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.2
15.2
62
172
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.4
14.3
44
91
QCE20
NOMESCO Finland
Excision and repair of scar or web of skin of upper limb
145.3
13.5
14
*
N02BE01
ATC
paracetamol; systemic, rectal
3.2
13.5
316
2541
TQW99
NOMESCO Finland
Other minor procedure on skin
8.1
13.5
30
40
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
41.8
13.3
16
*
N02AX02
ATC
tramadol; systemic, rectal
2.4
13.2
156
873
ZXA10
NOMESCO Finland
Bilateral
3.1
13.1
83
322
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
12.5
117
576
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
5.8
12.3
35
66
WX110
NOMESCO Finland
Local anesthesy
2.5
12.1
280
2133
N03AX16
ATC
pregabalin; oral
2.7
12.1
96
430
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.6
12.0
42
100
J01FF01
ATC
clindamycin; systemic
2.5
11.9
114
564
N62
ICD-10 Finland
Hypertrophy of breast
5.2
11.9
37
78
WX002
NOMESCO Finland
Sedation and analgesia
2.8
11.7
86
367
S18
ICPC
Laceration/cut
2.3
11.5
149
859
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
17.8
11.3
17
10
J01DB01
ATC
cefalexin; oral
2.7
11.0
309
2523
E0000UV
ATC
NA
2.2
10.9
163
994
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.8
10.9
36
81
ZXA05
NOMESCO Finland
Left side
2.5
10.6
96
456
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.2
10.6
141
814
N06AX16
ATC
venlafaxine; oral
2.8
10.5
74
307
N05BA04
ATC
oxazepam; oral
2.4
10.4
103
515
P01AB01
ATC
metronidazole; oral, rectal
2.1
10.2
165
1033
WX402
NOMESCO Finland
General anaesthesia
2.6
10.0
81
361
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
41.3
10.0
12
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
10.0
58
212
TQW40
NOMESCO Finland
Remowal of suture of skin
4.0
9.9
39
105
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.1
9.9
38
100
N05CF01
ATC
zopiclone; oral
2.3
9.8
113
605
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
3.7
9.6
43
129
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
10.5
9.6
18
18
ZZR00
NOMESCO Finland
Flap of skin
12.8
9.4
16
13
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.0
9.3
173
1134
J01MA12
ATC
levofloxacin; systemic
2.8
9.3
66
271
A46
ICD-10 Finland
Erysipelas
3.3
9.1
47
158
B01AB05
ATC
enoxaparin; parenteral
2.2
9.1
105
563
N06AB04
ATC
citalopram; systemic
2.3
8.9
92
466
M79.6
ICD-10 Finland
Pain in limb
2.1
8.9
140
855
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
7.5
8.9
20
28
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
8.8
51
187
L28
ICPC
Limited function/disability (L)
3.0
8.8
51
187
R03AC02
ATC
salbutamol; inhalant
2.0
8.6
203
1442
HAE99
NOMESCO Finland
Other reconstruction of breast
20.6
8.5
12
6
QDE20
NOMESCO Finland
Excision and repair of scar or web of skin of lower limb
92.1
8.4
9
*
QDE30
NOMESCO Finland
Excision and repair of surgical scar in lower limb
+∞
8.4
8
*
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
9.8
8.4
16
17
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
8.3
67
298
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
8.3
132
804
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
7.8
8.3
18
24
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
34.2
8.1
10
*
J01DA01
ATC
[U] cefalexin; systemic
1.9
8.1
232
1752
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.4
7.9
69
319
N06AX11
ATC
mirtazapine; oral
2.0
7.9
117
690
SAA04
NOMESCO Finland
Special inverstigation of mouth
3.6
7.8
35
106
A01
ICPC
Pain general/multiple sites
3.3
7.7
38
124
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.2
7.7
39
130
A08
ICPC
Swelling
5.4
7.7
22
43
E000002
ATC
NA
2.6
7.6
57
244
H02AB06
ATC
prednisolone; systemic
1.9
7.5
160
1073
ZZR10
NOMESCO Finland
Flap of skin and muscle
13.7
7.4
12
9
H02AB09
ATC
hydrocortisone; systemic
7.1
7.4
17
25
N06AB10
ATC
escitalopram; oral
2.1
7.2
91
499
R52.2
ICD-10 Finland
Other chronic pain
5.2
7.2
21
42
N05BA01
ATC
diazepam; systemic, rectal
2.6
7.2
55
237
D06
ICPC
Abdominal pain localized other
3.0
7.2
41
148
TQW20
NOMESCO Finland
Tatoe
8.2
7.2
15
19
A06AD11
ATC
lactulose; oral
2.9
7.1
44
166
S29
ICPC
Skin symptom/complaint other
2.3
7.1
67
324
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.8
7.0
22
48
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.5
7.0
31
94
N05AH04
ATC
quetiapine; oral
2.2
7.0
74
376
E66.8
ICD-10 Finland
Other obesity
3.3
6.9
34
111
E000001
ATC
NA
2.1
6.9
89
491
GBB00
NOMESCO Finland
Tracheostomy
14.1
6.9
11
8
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
6.9
122
764
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.3
6.8
33
107
R05
ICD-10 Finland
Cough
2.2
6.8
71
359
X58
ICD-10 Finland
Exposure to other specified factors
2.4
6.8
62
293
A02BC02
ATC
pantoprazole; systemic
1.8
6.7
217
1655
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.4
6.6
55
249
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.8
6.6
208
1568
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
6.6
95
548
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.6
6.6
48
202
R06AE07
ATC
cetirizine; oral
1.8
6.5
169
1196
AA1AD
NOMESCO Finland
CT of head and brain
2.2
6.5
69
351
N03AE01
ATC
clonazepam; systemic
3.7
6.5
27
78
QDE35
NOMESCO Finland
Repair of skin defect in lower limb after surgery or injury
71.1
6.4
7
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.4
6.4
30
95
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.9
6.4
38
142
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
6.8
6.4
15
23
D07AC13
ATC
mometasone; topical
1.9
6.4
103
618
A02BC01
ATC
omeprazole; systemic
2.0
6.3
95
558
ZXA00
NOMESCO Finland
Right side
2.0
6.3
85
479
D07AA02
ATC
hydrocortisone; topical
2.3
6.3
62
305
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
6.3
199
1494
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.6
6.3
46
192
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
6.3
154
1066
EDC38
NOMESCO Finland
Open reduction and fixation of fracture of body of mandible
+∞
6.3
6
*
QBE00
NOMESCO Finland
Excision of loose skin or fold of skin from trunk
+∞
6.3
6
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.7
6.3
26
75
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
27.2
6.3
8
*
UKC02
NOMESCO Finland
Cystoscopy
2.7
6.2
41
164
R60.0
ICD-10 Finland
Localized oedema
2.8
6.2
39
149
A02BC05
ATC
esomeprazole; systemic
1.8
6.1
138
930
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
6.1
71
376
QAB00
NOMESCO Finland
Suture of skin of head or neck
8.8
6.1
12
14
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.5
6.1
46
198
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
10.3
6.1
11
11
HA1AA
NOMESCO Finland
X-ray mammography
2.8
6.0
38
146
D07AD01
ATC
clobetasol; topical
2.3
6.0
58
283
TKC20
NOMESCO Finland
Catheterisation of bladder
3.9
6.0
23
62

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
202
1184
2.43
16.83
6.3
4.2
36.4
36.5
g/l
0.15
188
1106
72
286
2.85
13.11
5.3
3.2
—
—
—
0
0
223
1467
2.18
12.97
11.3
8.0
0.0
0.0
e9/l
1.07
186
1193
86
386
2.57
12.28
2.6
2.2
2.5
2.4
g/l
0.35
76
358
92
440
2.42
11.41
3.4
3.1
0.8
0.8
mmol/l
0.33
78
414
130
723
2.18
11.27
2.6
2.1
2.7
2.9
mg/l
0.66
117
614
145
849
2.11
10.95
5.0
3.5
7.4
7.4
ph
0.88
35
149
72
315
2.57
10.76
6.7
5.0
1.1
1.0
mmol/l
0.63
66
290
78
355
2.49
10.73
2.8
2.3
23.3
23.7
%
0.09
69
302
214
1458
2.01
10.53
6.7
5.6
0.7
0.7
%
0.02
205
1363
231
1617
2.02
10.52
6.6
5.4
0.5
0.5
e9/l
0.10
201
1422
232
1629
2.01
10.45
6.6
5.4
0.0
0.0
e9/l
0.94
204
1427
161
1000
2.02
10.22
4.8
3.0
2.3
2.4
mmol/l
0.69
144
892
95
487
2.25
9.92
3.0
2.5
2.4
2.4
mmol/l
0.26
82
428
81
388
2.36
9.91
2.9
1.9
—
—
—
0
0
86
423
2.32
9.90
2.7
2.2
14.1
14.2
umol/l
0.04
77
388
235
1683
1.96
9.71
6.5
5.5
2.0
2.0
e9/l
0.02
208
1513
218
1523
1.95
9.69
6.7
5.4
2.9
2.8
%
0.44
209
1424
219
1535
1.95
9.61
6.9
5.7
8.1
8.1
%
0.01
210
1448
224
1588
1.94
9.44
6.8
5.5
29.9
29.2
%
0.52
212
1493
107
590
2.11
9.24
3.7
2.2
7.8
7.8
e6/l
0.00
97
526
158
1007
1.94
9.07
6.2
5.2
—
—
—
0
0
238
1741
1.91
8.91
4.8
4.3
6.2
6.4
mmol/l
0.73
224
1583
233
1693
1.90
8.90
6.8
5.9
0.2
0.2
e9/l
0.21
209
1513
169
1109
1.91
8.83
2.1
1.8
98.2
97.9
pmol/l
0.03
94
562
78
386
2.27
8.79
1.4
1.2
—
—
—
0
0
220
1576
1.88
8.72
6.5
5.3
56.1
56.7
%
0.32
210
1487
252
1894
1.90
8.51
9.6
8.7
4.0
4.0
e9/l
0.15
225
1666
218
1568
1.86
8.42
7.3
5.5
9.1
10.3
umol/l
1.72
208
1484
301
2419
1.99
8.07
9.6
6.6
74.4
74.1
u/l
0.05
287
2260
129
797
1.91
7.93
4.5
2.7
0.2
0.4
e6/l
1.21
94
587
100
568
2.01
7.84
3.9
2.4
509.4
550.0
mosm/kgh2o
1.06
88
488
224
1653
1.81
7.69
3.9
2.7
127.3
86.5
ug/l
0.55
210
1547
149
974
1.85
7.63
7.3
6.2
1.1
1.1
inr
0.14
61
315
67
331
2.23
7.53
2.0
1.5
—
—
—
0
0
127
793
1.88
7.49
6.8
6.5
—
—
—
0
0
152
1006
1.83
7.44
2.9
2.0
—
—
—
0
0
268
2102
1.84
7.38
3.9
3.1
—
—
—
0
0
137
882
1.84
7.31
4.7
2.8
60.9
47.4
e6/l
0.12
106
663
109
654
1.92
7.23
5.2
3.7
—
—
—
0
0
83
455
2.04
7.12
2.2
1.6
1338.3
1147.5
nmol/l
1.01
64
350
48
213
2.42
6.88
4.8
3.4
1.2
1.2
mmol/l
0.51
40
179
54
253
2.31
6.86
1.4
1.3
28.1
25.7
iu/l
0.18
45
212
125
799
1.82
6.74
4.0
2.6
—
—
—
0
0
130
842
1.81
6.70
1.5
1.6
1.4
1.4
mmol/l
0.49
105
740
342
2942
2.14
6.69
22.0
13.6
13.6
13.5
%
0.51
337
2891
19
51
3.86
6.44
4.5
1.9
2.0
2.7
mmol/l
0.65
13
35
176
1256
1.72
6.41
6.7
5.4
1.2
1.2
mmol/l
0.24
158
1153
190
1385
1.71
6.40
7.4
6.2
1.2
1.2
mmol/l
0.43
151
1180
49
228
2.31
6.32
4.2
3.9
0.2
0.5
%
0.91
11
50
320
2710
1.91
6.25
5.5
4.0
14.5
14.5
pmol/l
0.12
298
2499
52
250
2.24
6.21
1.8
2.8
1.7
1.7
%
0.07
45
221
184
1340
1.69
6.15
2.3
1.9
—
—
—
0
0
158
1106
1.71
6.10
5.2
3.3
51.4
69.4
e6/l
0.34
109
730
45
206
2.34
6.02
6.0
7.5
—
—
—
0
0
119
783
1.74
5.68
1.5
1.4
2.1
2.2
g/l
0.54
67
480
16
42
3.93
5.59
3.1
1.7
—
—
—
0
0
98
620
1.77
5.32
1.7
1.5
20.1
21.8
nmol/l
0.63
87
540
23
80
2.99
5.28
2.9
3.2
—
—
—
0
0
112
742
1.71
5.15
2.0
1.7
1.3
0.9
mg/l
0.57
77
557
354
3162
2.06
5.07
6.2
4.7
1.7
1.8
mu/l
0.85
344
2946
372
3389
2.44
5.04
18.5
11.0
20.7
20.1
mg/l
0.13
309
2544
50
261
2.05
4.85
4.2
4.1
0.6
0.9
%
0.53
14
84
14
37
3.89
4.85
1.8
1.5
—
—
—
0
0
273
2277
1.63
4.83
5.3
3.9
—
—
—
0
0
120
824
1.65
4.78
5.4
4.2
—
—
—
0
0
365
3313
2.19
4.76
18.8
11.7
3.9
3.9
mmol/l
0.43
355
3202
81
500
1.78
4.75
3.4
3.2
257.2
300.4
ng/l
0.06
55
315
13
33
4.04
4.75
1.5
2.4
—
—
—
0
0
47
242
2.07
4.73
4.4
4.3
0.0
0.1
%
1.94
14
71
129
906
1.63
4.68
1.4
1.3
1.0
2.2
u/ml
0.76
32
242
45
229
2.09
4.67
4.5
4.3
0.0
0.2
%
0.65
11
58
364
3305
2.16
4.66
18.6
11.6
139.6
139.6
mmol/l
0.27
356
3206
15
43
3.59
4.66
3.6
1.9
17.6
15.9
%
—
8
18
42
210
2.12
4.57
1.4
1.2
—
—
—
0
0
198
1562
1.53
4.23
5.6
3.8
—
—
—
0
0
40
203
2.08
4.19
3.8
3.9
82.0
71.2
ng/l
0.45
32
181
77
485
1.73
4.18
1.5
1.5
—
—
—
0
0
42
221
2.01
4.00
3.6
3.5
2.3
1.9
mmol/l
0.28
34
172
39
200
2.05
3.98
1.1
1.1
—
195.0
—
0
6
34
166
2.15
3.94
2.3
2.9
69.7
71.3
e9/l
0.08
22
130
115
816
1.58
3.90
2.7
2.0
148.5
235.9
u/l
0.53
108
774
16
54
3.04
3.89
3.8
3.1
61.3
55.8
%
0.85
16
54
202
1639
1.47
3.55
4.2
3.2
0.0
0.0
estimate
0.00
62
316
126
933
1.51
3.48
3.8
2.6
—
—
—
0
0
117
855
1.52
3.43
4.5
2.9
7.5
7.6
mmol/l
0.09
97
730
15
53
2.90
3.39
3.7
3.0
4.5
4.2
e9/l
0.16
15
53
15
53
2.90
3.39
1.3
1.9
134.5
132.4
g/l
—
10
34
14
48
2.99
3.33
1.6
2.3
—
—
—
0
0
200
1636
1.45
3.28
5.9
4.6
0.0
0.0
estimate
0.50
61
317
12
38
3.22
3.24
1.2
1.3
—
—
—
0
0
55
339
1.72
3.22
1.4
1.4
—
—
—
0
0
56
348
1.71
3.19
1.5
1.4
—
—
—
0
0
378
3557
2.19
3.19
12.7
8.8
27.7
25.5
u/l
0.44
371
3439
320
2881
1.56
3.12
5.3
4.7
37.6
38.5
mmol/mol
1.05
305
2713
201
1660
1.42
3.06
4.3
3.3
0.0
0.0
estimate
0.00
58
309
162
1287
1.44
3.05
3.6
3.0
—
—
—
0
0
16
64
2.56
2.91
1.3
1.2
—
—
—
0
0
22
104
2.18
2.80
1.1
1.2
—
—
—
0
0
9
23
3.98
2.79
1.2
1.4
8.5
9.5
umol/l
—
9
23
57
370
1.63
2.76
1.2
1.3
—
—
—
0
0
14
55
2.60
2.64
1.1
1.2
3.3
4.8
u/ml
—
6
26
11
38
2.95
2.60
1.2
1.3
—
—
nmol/l
—
0
0
377
3576
1.98
2.58
15.8
10.2
—
—
—
0
0
15
62
2.47
2.57
6.4
3.0
51.3
30.4
u/ml
0.37
15
62
60
402
1.58
2.56
1.4
1.2
—
—
—
0
0
35
204
1.78
2.51
3.5
1.8
—
—
—
0
0
31
175
1.84
2.46
3.8
1.9
—
—
—
0
0
24
124
2.00
2.46
1.2
1.3
13.8
10.5
u/l
0.41
19
97
23
117
2.02
2.46
1.0
1.1
—
—
—
0
0
10
34
2.99
2.43
1.3
1.5
—
—
—
0
0
36
214
1.75
2.42
2.3
1.6
—
—
—
0
0
15
64
2.40
2.41
1.5
1.3
—
—
—
0
0
6
12
5.06
2.41
2.3
1.5
23.5
28.4
umol/l
—
6
12
79
570
1.48
2.41
2.5
1.6
465.9
430.1
pmol/l
0.66
63
495
69
484
1.51
2.41
2.6
2.4
132.2
93.3
ug/g
0.71
51
377
41
254
1.68
2.39
2.1
2.2
3098.0
2893.5
u/l
—
7
111
16
71
2.31
2.37
1.1
1.3
—
—
—
0
0
16
71
2.31
2.37
1.1
1.0
—
—
—
0
0
123
966
1.40
2.37
4.4
2.9
—
—
—
0
0
32
186
1.78
2.32
1.5
1.6
247.2
282.3
mu/l
0.56
26
164
10
35
2.90
2.32
4.5
1.7
1.8
1.7
mmol/l
—
10
35
36
217
1.72
2.31
3.4
1.8
—
—
—
0
0
36
218
1.72
2.28
3.4
1.8
—
—
—
0
0
49
322
1.59
2.28
1.2
1.2
—
—
—
0
0
36
219
1.71
2.24
3.4
1.8
—
—
—
0
0
13
54
2.45
2.22
1.8
3.2
9.6
8.1
kpa
1.86
13
48
20
101
2.03
2.19
4.8
2.4
—
—
—
0
0
125
996
1.37
2.19
2.9
3.1
37.2
39.4
ng/l
0.04
65
561
120
950
1.38
2.18
3.1
2.3
61.1
54.9
u/l
0.54
114
879
9
30
3.05
2.16
1.3
2.5
3.1
4.0
nmol/l
—
9
30
9
30
3.05
2.16
1.1
1.1
—
—
—
0
0
272
2444
1.35
2.11
5.4
3.7
11.7
9.8
mm/h
1.28
249
2263
67
484
1.46
2.03
1.5
1.4
414.3
523.9
titre
0.38
14
102
47
317
1.55
1.97
1.2
1.2
195.3
160.2
iu/ml
0.16
13
141
11
45
2.49
1.94
4.6
2.0
—
—
—
0
0
7
22
3.22
1.89
1.3
1.6
11.4
11.6
%
—
7
22
30
183
1.69
1.88
1.8
2.7
66.8
67.2
g/l
0.12
30
171
8
28
2.89
1.87
1.6
2.6
—
—
—
0
0
5
12
4.20
1.83
1.4
2.9
61.6
113.1
nmol/l
—
5
12
23
131
1.80
1.82
1.6
1.7
—
—
—
0
0
10
41
2.48
1.77
1.4
6.5
—
—
—
0
0
6
18
3.37
1.75
3.0
4.3
—
—
—
0
0
9
36
2.53
1.75
1.7
1.3
—
—
—
0
0
11
48
2.33
1.72
1.1
1.2
—
—
—
0
0
12
55
2.22
1.69
1.8
5.5
26.7
28.0
mg/l
—
6
45
37
246
1.56
1.67
1.4
1.4
—
—
—
0
0
8
31
2.61
1.66
1.5
1.3
—
—
—
0
0
8
31
2.61
1.66
1.9
1.3
—
—
—
0
0
340
3205
1.41
1.66
20.2
11.9
40.2
40.2
%
0.01
279
2564
346
3280
1.41
1.55
4.6
4.2
2.8
2.9
mmol/l
0.14
332
3073
16
86
1.90
1.52
1.4
1.3
341.7
325.6
ug/g
—
10
48
9
37
2.46
1.49
1.8
2.1
—
—
—
0
0
13
66
2.00
1.45
1.3
1.4
115.9
114.5
u/ml
—
5
15
33
476
0.67
1.44
1.3
1.4
—
—
—
0
0
7
29
2.44
1.40
2.6
2.0
32.0
33.3
pg
—
7
29
11
53
2.11
1.39
2.0
1.4
3168.6
23101.7
e6/l
—
5
38
24
151
1.63
1.38
2.3
3.3
7.4
7.4
ph
—
9
11
24
151
1.63
1.38
2.3
3.3
5.2
5.2
kpa
0.05
24
142
6
23
2.63
1.37
2.2
2.2
—
—
—
0
0
105
869
1.28
1.36
4.6
3.4
0.0
0.0
estimate
0.50
61
319
25
160
1.60
1.35
5.1
2.5
—
—
—
0
0
41
294
1.44
1.33
1.3
1.4
—
—
—
0
0
114
956
1.27
1.33
2.0
1.9
—
—
—
0
0
332
3146
1.33
1.32
4.4
3.8
5.7
5.7
mmol/l
0.11
318
2909
9
43
2.12
1.31
1.6
2.9
3.3
103.2
u/ml
—
9
37
25
162
1.58
1.29
2.3
2.0
7.3
12.3
nmol/l
1.61
19
145
11
55
2.03
1.28
1.8
5.5
23.8
39.9
mg/l
—
5
45
13
70
1.89
1.25
2.2
2.5
—
—
—
0
0
6
25
2.42
1.25
3.0
4.0
—
—
—
0
0
6
25
2.42
1.25
1.5
1.1
—
—
—
0
0
87
712
1.28
1.23
3.4
3.3
—
—
—
0
0
5
19
2.65
1.22
2.4
7.7
—
—
—
0
0
94
779
1.27
1.20
2.8
3.1
—
—
—
0
0
6
26
2.33
1.19
1.2
1.3
—
—
—
0
0
340
3245
1.32
1.19
4.2
3.8
4.7
4.8
mmol/l
0.45
329
3057
22
142
1.58
1.17
1.7
2.7
—
—
—
0
0
5
20
2.52
1.15
1.6
1.3
2.2
10.4
u/field
—
5
13
389
3808
1.86
1.13
26.2
16.5
4.5
4.5
e12/l
0.61
384
3720
7
30
2.36
1.13
2.4
3.4
29.7
19.7
mu/l
—
7
30
13
73
1.81
1.12
1.2
1.2
—
—
—
0
0
11
59
1.89
1.08
1.1
1.1
0.4
2.7
u/ml
—
6
16
389
3811
1.83
1.08
26.3
16.5
6.8
6.7
e9/l
0.46
384
3719
35
255
1.41
1.07
4.5
4.0
3.5
24.8
ug/l
0.67
26
206
36
264
1.40
1.06
8.0
8.6
0.3
1.3
mmol/l
0.95
28
208
88
735
1.25
1.06
2.0
2.5
324.0
7826.7
umol/l
3.78
77
651
18
114
1.61
1.04
1.3
1.1
—
—
—
0
0
5
22
2.29
1.03
1.6
1.8
0.8
1.0
g/l
—
5
22
325
3101
1.26
1.01
3.8
3.4
1.2
1.2
mmol/l
0.02
308
2904
31
224
1.42
1.00
1.5
1.2
—
—
—
0
0
14
84
1.69
0.99
1.4
1.3
494.8
405.8
mg/l
0.37
14
76
59
726
0.78
0.98
2.9
3.5
1.0
1.0
kg/l
—
6
95
14
221
0.62
0.96
5.1
3.3
—
—
—
0
0
336
3228
1.26
0.91
4.2
3.8
1.5
1.5
mmol/l
0.02
319
3030
6
29
2.08
0.89
1.8
2.3
0.7
2.6
u/field
—
6
11
6
29
2.08
0.89
1.0
1.2
—
—
—
0
0
92
787
1.22
0.89
1.6
1.7
—
—
—
0
0
15
95
1.60
0.88
1.3
1.3
—
56.3
—
0
8
84
715
1.22
0.86
4.8
3.1
71.8
163.8
mg/l
0.42
55
436
37
284
1.33
0.85
22.5
15.9
1.3
1.2
inr
—
9
50
14
88
1.61
0.85
1.1
1.1
—
—
—
0
0
14
88
1.61
0.85
1.1
1.1
—
—
—
0
0
6
31
1.95
0.84
1.0
1.0
—
—
—
0
0
8
45
1.79
0.84
1.9
1.7
—
—
—
0
0
11
65
1.71
0.83
1.3
1.4
—
—
—
0
0
12
73
1.66
0.82
1.3
1.4
—
—
—
0
0
21
148
1.44
0.79
6.0
2.4
0.1
0.1
e6/l
0.86
21
143
15
98
1.55
0.79
2.5
3.1
0.4
0.2
g/l
—
8
39
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
6
34
1.78
0.76
1.3
1.3
208.8
395.8
pmol/l
—
6
29
18
254
0.69
0.76
6.3
3.7
—
—
—
0
0
5
24
2.10
0.74
1.2
1.3
—
—
—
0
0
5
24
2.10
0.74
1.8
1.2
1.8
1.9
mmol/l
—
5
24
5
25
2.01
0.73
1.2
1.0
—
—
—
0
0
5
25
2.01
0.73
1.0
1.5
—
—
—
0
0
12
76
1.60
0.72
1.1
1.1
0.2
0.7
u/ml
—
7
31
5
26
1.93
0.71
1.2
1.5
—
—
—
0
0
21
152
1.40
0.70
8.9
8.3
94.6
94.2
%
0.12
21
152
145
1321
1.15
0.68
3.0
2.4
—
—
—
0
0
13
86
1.53
0.67
2.7
1.6
0.5
4.3
ug/l
0.66
13
80
12
78
1.56
0.66
1.9
2.1
10.4
10.6
mg/l
0.05
12
70
29
225
1.31
0.65
2.2
2.4
21.7
42.8
u/ml
1.03
29
218
85
753
1.16
0.57
6.7
3.8
10.6
10.3
mg/mmol
0.02
53
460
11
74
1.50
0.54
1.1
1.2
3.5
3.6
mmol/l
0.14
11
66
6
39
1.55
0.53
1.0
1.5
—
—
—
0
0
15
203
0.73
0.53
2.9
2.8
—
—
—
0
0
21
162
1.31
0.51
1.1
1.1
—
—
—
0
0
15
110
1.38
0.49
1.1
1.2
—
—
—
0
0
13
93
1.41
0.48
6.6
4.5
—
—
—
0
0
11
154
0.71
0.48
1.2
1.3
—
—
—
0
0
7
47
1.50
0.48
3.6
1.5
—
—
—
0
0
13
94
1.40
0.46
1.2
1.1
1.7
2.1
u/ml
—
8
32
27
222
1.23
0.42
2.9
2.8
0.5
0.8
ug/l
1.82
17
115
0
15
0.00
0.41
0.0
1.0
—
296.1
—
0
9
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
1644.2
—
0
17
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
5
35
1.43
0.39
1.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
9
71
1.27
0.36
2.3
1.8
—
—
—
0
0
13
100
1.31
0.34
1.8
1.9
1.9
5.7
iu/l
—
6
37
6
45
1.34
0.34
1.2
1.2
—
—
—
0
0
24
281
0.84
0.30
1.0
1.3
—
—
—
0
0
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
17
141
1.21
0.26
7.4
2.5
—
—
—
0
0
20
169
1.19
0.26
1.3
1.3
153.9
249.9
miu/ml
0.80
12
89
18
151
1.20
0.25
1.4
1.3
—
—
—
0
0
9
77
1.17
0.24
7.9
3.2
—
—
—
0
0
114
1086
1.07
0.22
1.6
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
12.9
—
—
—
0
0
14
165
0.84
0.20
1.4
1.4
—
—
—
0
0
6
50
1.20
0.20
1.0
1.1
—
—
—
0
0
14
118
1.19
0.19
11.5
12.8
—
—
—
0
0
14
164
0.85
0.18
1.4
1.4
—
—
—
0
0
16
139
1.16
0.16
8.1
7.4
—
—
—
0
0
15
169
0.88
0.13
1.4
1.5
—
—
—
0
0
57
597
0.95
0.11
1.4
1.3
1.9
12.1
u/ml
4.01
23
240
22
203
1.09
0.10
1.0
1.1
—
—
—
0
0
10
114
0.87
0.09
2.5
3.3
—
—
—
0
0
25
267
0.93
0.08
2.0
1.6
—
—
—
0
0
15
137
1.10
0.07
2.2
2.2
—
—
—
0
0
9
103
0.87
0.06
16.6
8.3
—
—
—
0
0
61
625
0.97
0.05
1.3
1.3
15.7
29.4
iu/ml
1.51
12
210
22
228
0.96
0.02
1.6
2.2
4.6
4.1
e9/l
0.45
17
192
60
608
0.98
0.01
1.9
1.7
—
—
—
0
0
52
513
1.02
0.01
1.6
1.5
—
—
—
0
0
13
136
0.95
0.00
2.2
1.6
—
—
—
0
0
21
209
1.01
0.00
1.7
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
45
450
1.00
0.00
2.2
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
13.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
2.0
—
0
6
6
66
0.91
0.00
3.5
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
6
63
0.95
0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_STRIAEATROPHICAE and mortality.

Females

Parameter HR [95% CI] p-value
L12_STRIAEATROPHICAE 1.328 [1.01, 1.75] 0.045
Birth year 0.996 [0.99, 1.0] 0.317

During the follow-up period (1.1.1998 — 31.12.2019), 72 out of 1519 females with L12_STRIAEATROPHICAE died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_STRIAEATROPHICAE.

N-year risk Females Males
1 0.137% No data
5 0.764% No data
10 1.961% No data
15 3.999% No data
20 7.169% No data

Relationships between endpoints

Index endpoint: L12_STRIAEATROPHICAE – Striae atrophicae

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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