No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
312 |
4. Check minimum number of eventsNone |
312 |
5. Include endpointsNone |
312 |
6. Filter based on genotype QC (FinnGen only) |
298 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Kela reimbursement Agammaglobulinemia (D80-84)
based on the number of shared cases.
Similar with more cases:
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any reimbursement code in KELA
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 979 | 566 | 411 |
| Only index persons | 863 | 510 | 353 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 42.67 | 45.86 | 38.29 |
| Only index persons | 41.96 | 46.26 | 35.76 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 298 | 193 | 105 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.05 |
| Median age at first event (years) | 44.46 | 45.98 | 41.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 312
- Matched controls
- 3120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
307.7
312
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
307.7
272
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
233.8
194
*
ZX120
NOMESCO Finland
Intravenous
28.9
203.6
175
132
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
33.1
162.2
115
54
WW200
NOMESCO Finland
Immunization
45.7
144.0
89
27
J47
ICD-10 Finland
Bronchiectasis
81.8
129.8
70
11
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
56.8
127.7
74
17
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
23.8
123.0
98
59
J01MA12
ATC
levofloxacin; systemic
13.5
122.7
170
254
J01MA14
ATC
moxifloxacin; systemic
14.9
111.0
121
127
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
108.9
98
*
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
106.5
96
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
13.4
100.1
116
132
TDM10
NOMESCO Finland
Puncture of maxillary antrum
19.1
95.8
83
58
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
22.5
91.5
72
41
J18.9
ICD-10 Finland
Pneumonia, unspecified
9.1
86.4
162
330
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
13.8
85.8
92
92
6BA02, ,
NOMESCO Finland
528.3
84.3
80
*
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
80.8
74
*
TPH04
NOMESCO Finland
Cathetrisation of vein
8.3
79.7
171
397
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
9.4
79.3
125
207
C01CA24
ATC
epinephrine; parenteral
10.5
75.1
100
134
GD1AA
NOMESCO Finland
Thorax X-ray examination
9.1
73.3
239
825
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
12.6
72.2
80
83
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
69.4
64
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
14.0
68.1
69
62
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
67.2
62
*
TGC00
NOMESCO Finland
Bronchial lavation
24.4
62.3
46
22
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
12.3
60.9
67
68
H02AB06
ATC
prednisolone; systemic
7.9
60.6
244
971
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
60.4
56
*
R50.9
ICD-10 Finland
Fever, unspecified
7.2
60.2
119
245
GD1AD
NOMESCO Finland
Thorax CT examination
13.1
59.4
62
58
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
14.3
58.2
57
48
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.2
57.4
167
492
XW000
NOMESCO Finland
Bone marrow biopsy
16.9
55.7
49
34
Z01.8
ICD-10 Finland
Other specified special examinations
6.0
54.6
151
422
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
6.2
54.1
133
334
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
10.2
53.9
68
83
J45.1
ICD-10 Finland
Nonallergic asthma
8.4
51.0
77
117
H02AB09
ATC
hydrocortisone; systemic
18.5
50.4
42
26
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
21.1
49.9
39
21
UDH02
NOMESCO Finland
Rhinopharyngoscopy
8.2
49.8
77
120
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.1
49.5
77
121
J01.0
ICD-10 Finland
Acute maxillary sinusitis
5.3
47.4
171
585
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
8.5
43.7
63
90
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.8
41.5
160
565
XG410
NOMESCO Finland
Flow-volume spirometry
13.3
41.1
41
35
J01FA06
ATC
roxithromycin; oral
4.7
39.7
199
849
R03BB04
ATC
tiotropium bromide; inhalant
7.6
39.3
63
101
H02AB07
ATC
prednisone; oral
5.7
39.3
90
206
SPAT1262
SPAT
Handing over of treatment supplies
5.4
39.2
99
247
J45.9
ICD-10 Finland
Asthma, unspecified
4.9
38.1
115
332
A41.9
ICD-10 Finland
Sepsis, unspecified
14.4
38.1
36
28
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
8.4
37.7
54
76
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
9.2
37.3
49
62
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
+∞
37.2
35
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.4
36.8
70
134
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.7
36.7
116
346
J45.0
ICD-10 Finland
Predominantly allergic asthma
5.7
35.4
78
171
J01FA15
ATC
telithromycin; oral
5.6
34.7
78
174
J46
ICD-10 Finland
Status asthmaticus
13.1
32.1
32
27
R03DA04
ATC
theophylline; systemic, rectal
11.1
31.5
35
35
A07AA02
ATC
nystatin; oral
8.0
31.4
46
66
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
40.3
31.4
39
11
UJF30
NOMESCO Finland
Ileoscopy through colon
5.5
31.0
70
156
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.2
30.7
59
113
J01MA02
ATC
ciprofloxacin; systemic
3.8
30.2
164
704
R03DC03
ATC
montelukast; oral
4.2
29.9
108
350
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
6.7
29.4
51
88
WZC30
NOMESCO Finland
Teaching
4.4
28.9
94
281
J45.8
ICD-10 Finland
Mixed asthma
11.0
28.7
32
32
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
4.4
28.7
241
1363
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.3
28.6
45
70
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
9.0
28.3
37
46
JN4BD
NOMESCO Finland
Extensive body CT
5.5
27.8
61
132
J01FF01
ATC
clindamycin; systemic
3.7
27.4
135
536
R03BA02
ATC
budesonide; inhalant
3.9
26.7
104
352
R03BB01
ATC
ipratropium bromide; inhalant
11.3
26.6
29
28
D83.8
ICD-10 Finland
Other common variable immunodeficiencies
+∞
26.4
25
*
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
+∞
26.4
25
*
R01AD09
ATC
mometasone; nasal
3.7
26.2
213
1151
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
26.2
78
217
Z3231
NOMESCO Finland
Registered nurse
3.5
26.1
138
570
J01FA10
ATC
azithromycin; systemic
4.6
25.8
257
1580
R03AC02
ATC
salbutamol; inhalant
3.9
25.4
235
1367
R01AD08
ATC
fluticasone; nasal
3.4
25.2
149
657
R03BA08
ATC
ciclesonide; inhalant
5.0
25.1
62
148
ZXA10
NOMESCO Finland
Bilateral
3.9
24.9
94
310
J01FA09
ATC
clarithromycin; systemic
3.3
24.2
154
706
WVA20
NOMESCO Finland
Medicine administration
9.9
24.2
29
32
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.2
23.9
44
80
L03AA02
ATC
filgrastim; parenteral
8.9
23.9
31
38
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.1
23.5
79
239
TAB00
NOMESCO Finland
Lumbar puncture
6.2
23.1
43
79
UJF32
NOMESCO Finland
Coloscopy
3.5
22.5
105
395
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
8.6
22.5
30
38
R05
ICD-10 Finland
Cough
3.5
22.1
104
393
XQ800
NOMESCO Finland
Prick test
4.8
22.1
56
136
OAB50, ,
SPAT
6.5
21.9
38
65
JN4AD
NOMESCO Finland
Body CT examination
5.0
21.8
52
120
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
9.1
21.3
27
32
J32.4
ICD-10 Finland
Chronic pansinusitis
26.5
21.3
29
12
WW500
NOMESCO Finland
Blood transfusion
7.8
20.7
30
42
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
35.3
20.5
26
8
M05BA04
ATC
alendronic acid; oral
6.0
20.5
39
73
B29
ICPC
Lymph/immune mech sympt/complt other
51.7
20.5
24
5
ZX112
NOMESCO Finland
Subcutaneous
9.1
20.4
26
31
C03CA01
ATC
furosemide; systemic
3.5
20.1
87
310
R01AD05
ATC
budesonide; nasal
4.9
20.0
48
111
Z31.5
ICD-10 Finland
Genetic counselling
4.9
19.7
47
108
H02AB04
ATC
methylprednisolone; systemic
3.8
19.7
72
229
R03AC13
ATC
formoterol; inhalant
6.2
19.5
35
62
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
19.2
122
545
J01AA02
ATC
doxycycline; systemic
4.7
19.1
277
1959
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
74.6
18.9
21
*
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
18.9
18
*
J06BA02
ATC
immunoglobulins, normal human, for intravascular adm.; systemic
+∞
18.9
18
*
WX882
NOMESCO Finland
High dependency care
8.0
18.5
26
35
N02AA05
ATC
oxycodone; systemic
3.7
18.4
69
223
R06AE07
ATC
cetirizine; oral
2.9
18.2
185
1054
XF400
NOMESCO Finland
ECG with 12 standard connections
3.5
18.2
74
252
Z3226
NOMESCO Finland
Physiotherapist
3.2
18.2
92
359
R03AC12
ATC
salmeterol; inhalant
6.5
18.1
31
52
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.0
18.0
222
1398
M36.8*D80.1
ICD-10 Finland
Systemic disorders of connective tissue in hypogammaglobulinaemia
+∞
17.9
17
*
A04AA01
ATC
ondansetron; systemic, rectal
4.7
17.9
45
108
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
6.5
17.7
30
50
Z2221
NOMESCO Finland
Medical doctor
2.9
17.4
126
598
R03AK08
ATC
formoterol and beclometasone; inhalant
5.4
17.3
36
73
J05AB11
ATC
valaciclovir; oral
3.3
17.2
81
302
J02AC01
ATC
fluconazole; systemic
2.7
17.0
166
916
H04.10
ICD-10 Finland
Dry eye syndrome
3.6
17.0
65
212
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
16.8
16
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
7.8
16.8
24
33
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
7.8
16.8
24
33
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.1
16.7
51
142
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
24.7
16.7
23
10
J31.0
ICD-10 Finland
Chronic rhinitis
3.9
16.7
56
167
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
5.5
16.6
34
68
N03AX16
ATC
[U] pregabalin
3.0
16.5
99
423
WZC00
NOMESCO Finland
Treatment plan or consultation
2.7
16.4
150
798
J01DA06
ATC
[U] cefuroxime
3.2
16.2
77
287
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
26.2
16.2
22
9
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.8
16.2
56
170
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.6
16.2
42
103
SPAT1255
SPAT
Intravenous administration of medicine
5.2
16.1
35
74
R06.0
ICD-10 Finland
Dyspnoea
2.9
15.9
103
457
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.8
15.9
38
87
J05AB01
ATC
aciclovir; systemic
2.9
15.9
103
458
L04AX01
ATC
azathioprine; systemic
6.0
15.9
29
52
A03FA01
ATC
metoclopramide; systemic, rectal
2.9
15.8
100
439
ZX110
NOMESCO Finland
Intracutaneous
89.7
15.7
17
*
ZX108
NOMESCO Finland
Inhalation
40.3
15.6
19
5
R4110
NOMESCO Finland
Physiotherapy
2.7
15.6
117
561
ZYC01
NOMESCO Finland
Remote contact by phone
4.4
15.3
41
103
N02AX02
ATC
tramadol; systemic, rectal
2.6
15.2
158
885
ZXA05
NOMESCO Finland
Left side
2.9
15.1
94
408
JN3AD
NOMESCO Finland
Abdominal CT examination
3.7
15.0
52
158
XA800
NOMESCO Finland
Neuropsychological investigation
4.8
14.9
36
83
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
14.9
147
801
B99
ICPC
Blood/lymph/spleen disease other
59.7
14.9
17
*
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
26.6
14.9
20
8
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.7
14.8
119
587
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
14.7
72
272
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
84.2
14.7
16
*
GD1DG
NOMESCO Finland
Extremely extensive MRI examination of pleura with high field magnet
+∞
14.7
14
*
D84.9
ICD-10 Finland
Immunodeficiency, unspecified
+∞
14.7
14
*
ZXE00
NOMESCO Finland
One hour or less
2.5
14.5
154
867
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
14.5
90
389
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
14.3
138
741
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.8
14.3
23
36
R03BA01
ATC
beclometasone; inhalant
3.2
14.3
65
235
R03AC03
ATC
terbutaline; inhalant
3.2
14.3
66
241
B28
ICPC
Limited function/disability (B)
44.7
14.2
17
*
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
44.7
14.2
17
*
ZX121
NOMESCO Finland
Central venous catheter
44.7
14.2
17
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
14.0
63
226
A01AB09
ATC
miconazole; local oral
4.0
14.0
43
120
XG474
NOMESCO Finland
Exhalation nntrogen oxide
6.1
13.9
25
44
A07EA06
ATC
budesonide; oral, local oral
5.2
13.9
30
63
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
5.8
13.8
26
48
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
4.8
13.7
32
72
D83.1
ICD-10 Finland
Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
+∞
13.6
13
*
M04AA01
ATC
allopurinol; systemic
3.9
13.6
44
127
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.8
13.6
86
374
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.7
13.5
48
148
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
22.4
13.5
19
9
R03AK07
ATC
formoterol and budesonide; inhalant
2.7
13.4
91
410
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
12.3
13.0
23
20
ZXA00
NOMESCO Finland
Right side
2.6
13.0
97
457
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.9
12.8
72
293
B03BA03
ATC
hydroxocobalamin; parenteral
5.8
12.8
24
44
R01AD58
ATC
fluticasone, combinations; nasal
2.5
12.8
112
570
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
33.6
12.7
16
5
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
12.7
50
165
A02BC01
ATC
omeprazole; systemic
2.6
12.6
100
484
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
25.6
12.6
17
7
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.0
12.4
63
242
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
39.2
12.3
15
*
WX892
NOMESCO Finland
Monitored bed care
3.9
12.3
38
106
ZX114
NOMESCO Finland
Intramuscular
11.7
12.2
22
20
A07AA09
ATC
vancomycin; oral
19.0
12.2
18
10
R03BA05
ATC
fluticasone; inhalant
2.6
12.1
85
387
R01BA52
ATC
pseudoephedrine, combinations; oral
2.4
12.1
119
635
A02BC03
ATC
lansoprazole; oral
2.5
12.1
105
530
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
12.4
12.0
21
18
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
48.6
12.0
14
*
J01DA01
ATC
[U] cefalexin
2.4
12.0
216
1495
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.2
11.9
33
85
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
67.6
11.7
13
*
J01DB01
ATC
cefalexin; oral
3.7
11.6
283
2254
R01AD12
ATC
fluticasone furoate; nasal
2.3
11.6
134
764
A46
ICD-10 Finland
Erysipelas
3.1
11.6
54
197
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.5
11.5
29
69
A02BC02
ATC
pantoprazole; systemic
2.4
11.5
221
1558
ZXD05
NOMESCO Finland
Urgent procedure
2.3
11.3
118
644
Z2446
NOMESCO Finland
Social worker
3.5
11.2
42
134
R03AK03
ATC
[U] fenoterol and ipratropium bromide
6.0
11.2
20
35
J15.8
ICD-10 Finland
Other bacterial pneumonia
45.0
11.0
13
*
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
16.3
11.0
17
11
D64.9
ICD-10 Finland
Anaemia, unspecified
3.7
10.9
36
105
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
10.9
62
253
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.9
10.8
33
91
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
5.9
10.8
20
36
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
10.8
61
247
WX002
NOMESCO Finland
Sedation and analgesia
2.6
10.8
72
318
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
22.4
10.8
15
7
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
5.3
10.7
22
44
N06AX21
ATC
duloxetine; oral
2.9
10.6
58
231
J01
ICD-10 Finland
Acute sinusitis
3.8
10.5
33
93
ZY010
NOMESCO Finland
Hospital outpatient
3.8
10.5
34
98
R06AE09
ATC
levocetirizine; oral
2.7
10.4
67
290
M05BX04
ATC
denosumab; parenteral
5.0
10.4
23
49
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
33.8
10.4
13
*
J96.0
ICD-10 Finland
Acute respiratory failure
33.8
10.4
13
*
A28
ICPC
Limited function/disability NOS
3.1
10.4
47
168
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.2
10.4
45
157
J01DC02
ATC
cefuroxime; systemic
3.9
10.3
31
85
S01GX01
ATC
cromoglicic acid; ophthalmic
2.4
10.2
89
445
R03BC03
ATC
nedocromil; inhalant
3.6
10.2
35
105
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.3
10.2
21
42
N03AX11
ATC
topiramate; oral
5.1
10.2
22
46
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.7
10.1
33
96
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
10.0
37
117
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
5.2
9.9
21
43
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.8
9.9
57
233
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
27.0
9.9
13
5
A06AD11
ATC
lactulose; oral
3.1
9.8
45
162
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
14.0
9.8
16
12
C10AC01
ATC
colestyramine; oral
5.3
9.7
20
40
R01AD01
ATC
beclometasone; nasal
2.6
9.7
68
307
L04AA06
ATC
mycophenolic acid; systemic
9.6
9.7
19
21
WX704
NOMESCO Finland
Intubation
3.3
9.6
38
125
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.2
9.6
40
136
B01AB05
ATC
enoxaparin; parenteral
2.3
9.5
99
532
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
9.5
132
796
R81
ICPC
Pneumonia
5.4
9.5
19
37
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
5.4
9.5
19
37
D07AB08
ATC
desonide; topical
2.8
9.5
51
201
1XC02, ,
NOMESCO Finland
31.1
9.5
12
*
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
12.9
9.5
16
13
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
9.5
132
798
D86.0
ICD-10 Finland
Sarcoidosis of lung
+∞
9.4
9
*
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
+∞
9.4
9
*
D84.19
ICD-10 Finland
Unspecified defect in the complement system
+∞
9.4
9
*
R03AK11
ATC
formoterol and fluticasone; inhalant
7.7
9.4
21
29
R01AD11
ATC
triamcinolone; nasal
3.1
9.4
43
155
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.5
9.3
33
101
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
14.2
9.3
15
11
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.3
9.2
94
500
Z71.8
ICD-10 Finland
Other specified counselling
2.1
9.2
117
681
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
9.2
78
384
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
10.5
9.1
17
17
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
9.1
67
309
N05BA01
ATC
diazepam; systemic, rectal
2.7
9.0
54
225
R1250
NOMESCO Finland
Evaluation of functional capability
7.2
9.0
21
31
H65.3
ICD-10 Finland
Chronic mucoid otitis media
4.9
9.0
20
43
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.6
8.9
20
28
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
4.4
8.9
23
56
P01AB01
ATC
metronidazole; oral, rectal
2.1
8.9
144
916
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
8.8
85
441
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.8
8.8
47
184
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
4.5
8.8
22
52
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.2
8.8
36
121
J01CF05
ATC
flucloxacillin; systemic
3.5
8.7
31
95
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
51.5
8.7
10
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
8.7
41
150
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.2
8.7
36
122
R06AX27
ATC
desloratadine; oral
2.1
8.7
119
710
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
4.4
8.6
22
53
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.4
8.6
22
53
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.7
8.6
28
81
E0000UV, ,
ATC
2.0
8.6
149
968
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
28.4
8.5
11
*
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
28.4
8.5
11
*
Z50.1
ICD-10 Finland
Other physical therapy
4.0
8.5
25
67
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
8.4
50
207
H65.2
ICD-10 Finland
Chronic serous otitis media
9.9
8.4
16
17
2790C
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI ALIA]
+∞
8.4
8
*
27510
ICD-8 Finland
Plasma protein abnormalities, Hypogammaglobulinaemia
+∞
8.4
8
*
2790B
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI A]
+∞
8.4
8
*
D81.0
ICD-10 Finland
Severe combined immunodeficiency [SCID] with reticular dysgenesis
+∞
8.4
8
*
D73.1
ICD-10 Finland
Hypersplenism
+∞
8.4
8
*
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
8.4
8
*
J20
ICD-10 Finland
Acute bronchitis
2.8
8.4
45
177
J45
ICD-10 Finland
Asthma
2.9
8.3
42
160
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.6
8.3
20
46
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.8
8.3
45
178
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
15.0
8.3
13
9
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.2
8.2
19
28
J01DA08
ATC
[U] cefaclor
2.7
8.2
49
204
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
17.8
8.1
12
7
C03DA01
ATC
spironolactone; oral
3.1
8.1
36
127
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
8.1
44
174
A04AA02
ATC
granisetron; systemic, transdermal
3.5
8.0
28
85
UDM02
NOMESCO Finland
Sinoscopy
7.3
7.9
18
26
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
7.3
7.9
18
26
A06AC01
ATC
ispaghula (psylla seeds); oral
2.2
7.9
84
452
J01CA04
ATC
amoxicillin; systemic
2.7
7.9
275
2286
J01.4
ICD-10 Finland
Acute pansinusitis
11.2
7.9
14
13
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
11.2
7.9
14
13
N03AX12
ATC
[U] gabapentin; oral
2.4
7.8
64
308
WX720
NOMESCO Finland
Own respiration
4.1
7.8
22
57
UJF92
NOMESCO Finland
Capsular endoscopy
6.7
7.8
19
30
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
7.8
7.8
17
23
A02BC05
ATC
esomeprazole; systemic
2.0
7.8
135
869
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
15.5
7.8
12
8
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
46.2
7.8
9
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.2
7.7
21
53
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.1
7.7
97
557
RD210, ,
NOMESCO Finland
6.5
7.7
19
31
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
18.9
7.7
11
6
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.9
7.6
38
143
ZX100
NOMESCO Finland
Oral
12.3
7.6
13
11
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.9
7.6
23
63
SBA00
NOMESCO Finland
Microbiological examinations
6.8
7.5
18
28
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
82.0
7.4
8
*
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
13.8
7.4
12
9
D70.89
ICD-10 Finland
Neutropenic splenomegaly
11.2
7.4
13
12
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
7.4
45
189
D84.1
ICD-10 Finland
Defects in the complement system
+∞
7.3
7
*
2790A
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[AGAMMAGLOBULINAEMIA (BRUTON)]
+∞
7.3
7
*
D81.1
ICD-10 Finland
Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
+∞
7.3
7
*
I50.9
ICD-10 Finland
Heart failure, unspecified
3.4
7.3
27
85
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.6
7.3
16
22
M03BX01
ATC
baclofen; systemic
7.6
7.3
16
22
DMB00
NOMESCO Finland
Endonasal trephine of maxillary antrum
16.2
7.3
11
7
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
4.7
7.3
17
38
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.2
7.3
29
96
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
7.2
103
616
WX872
NOMESCO Finland
Intensive care
3.9
7.2
21
56
C08DA01
ATC
verapamil; systemic
3.9
7.2
21
56
N05CD07
ATC
temazepam; oral
2.9
7.2
35
130
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
8.2
7.2
15
19
GD1BG
NOMESCO Finland
MRI of lungs and pleura with high intensity magnet
30.8
7.2
9
*
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
20.6
7.2
10
5
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
12.4
7.1
12
10
D06AX01
ATC
fusidic acid; topical
2.6
7.1
42
173
A41.8
ICD-10 Finland
Other specified sepsis
9.1
7.1
14
16
M05BA07
ATC
risedronic acid; oral
9.1
7.1
14
16
K90.0
ICD-10 Finland
Coeliac disease
4.4
7.1
18
43
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
7.1
50
225
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
6.1
7.0
18
31
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
6.1
7.0
18
31
R11
ICD-10 Finland
Nausea and vomiting
2.7
7.0
38
150
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.6
7.0
23
67
R4190
NOMESCO Finland
Nutritional therapy
3.6
7.0
23
67
M13.9
ICD-10 Finland
Arthritis, unspecified
3.0
7.0
32
115
R49.01
ICD-10 Finland
Functional dysphonia
4.3
6.9
18
44
N03AX09
ATC
lamotrigine; oral
3.1
6.9
29
99
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
8.6
6.9
14
17
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
8.6
6.9
14
17
M35.7
ICD-10 Finland
Hypermobility syndrome
8.6
6.9
14
17
ZXD20
NOMESCO Finland
Day surgery
2.4
6.9
52
241
N03AE01
ATC
clonazepam; systemic
3.4
6.9
25
78
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
9.6
6.9
13
14
A01AB04
ATC
amphotericin B; local oral
4.1
6.8
19
49
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.1
6.8
19
49
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
41.0
6.8
8
*
JN6AD
NOMESCO Finland
CT of torso and neck
8.1
6.7
14
18
R4120
NOMESCO Finland
Occupational therapy
2.9
6.7
32
118
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.9
6.7
32
118
B07.9
ICD-10 Finland
Verruca simplex
4.0
6.6
19
50
DPA30
NOMESCO Finland
Sphenotomy
12.6
6.6
11
9
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
7.1
6.6
15
22
FM2CE, ,
NOMESCO Finland
10.3
6.6
12
12
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
5.9
6.5
17
30
R13
ICD-10 Finland
Dysphagia
3.1
6.5
28
97
UDC00
NOMESCO Finland
Ear microscopy
2.9
6.5
31
114
127
Kela drug reimbursment
Transplant complication
7.7
6.5
14
19
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
71.2
6.4
7
*
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
71.2
6.4
7
*
WX725
NOMESCO Finland
Noninvasive ventilation
3.3
6.4
24
76
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
14.7
6.4
10
7
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
6.8
6.4
15
23
N02AC04
ATC
dextropropoxyphene; oral
6.8
6.4
15
23
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
6.8
6.4
15
23
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
6.4
22
66
XF404
NOMESCO Finland
Ambulatory ECG
2.9
6.4
31
115
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
8.4
6.4
13
16
A02BA02
ATC
ranitidine; systemic
2.2
6.4
57
284
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
11.3
6.3
11
10
P01BA02
ATC
hydroxychloroquine; oral
2.6
6.3
37
152
J05AH02
ATC
oseltamivir; oral
18.5
6.3
9
5
B03XA01
ATC
erythropoietin; parenteral
18.5
6.3
9
5
G04BE03
ATC
sildenafil; oral
18.5
6.3
9
5
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
6.3
40
171
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.4
6.3
23
72
3XA02, ,
NOMESCO Finland
+∞
6.3
6
*
D81.9
ICD-10 Finland
Combined immunodeficiency, unspecified
+∞
6.3
6
*
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
+∞
6.3
6
*
ZX131
NOMESCO Finland
Intrathecal
+∞
6.3
6
*
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
+∞
6.3
6
*
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
27.3
6.3
8
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
27.3
6.3
8
*
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
27.3
6.3
8
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
6.2
108
685
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
6.2
142
982
PJA10
NOMESCO Finland
Exploration of lymph nodes
7.9
6.2
13
17
N02BF02
ATC
pregabalin; oral
3.0
6.2
28
100
J06.0
ICD-10 Finland
Acute laryngopharyngitis
12.9
6.1
10
8
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
12.9
6.1
10
8
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
6.9
6.1
14
21
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
247
163
68.94
320.28
5.4
1.6
0.98
1.55
g/l
1.29
212
154
146
11
248.58
303.68
3.4
1.4
—
—
—
0
0
116
19
96.59
217.48
3.1
1.6
39.35
37.80
%
0.20
105
19
109
20
83.23
199.77
3.6
1.3
519.00
794.43
e6/l
0.73
91
14
108
20
82.06
197.53
3.6
1.3
0.19
0.20
e9/l
0.05
92
14
150
187
14.52
123.62
2.2
1.2
81.26
252.18
u/ml
0.72
100
173
250
610
16.59
121.12
5.5
1.4
1.22
2.30
g/l
14.33
173
391
83
47
23.70
106.39
6.0
5.4
676.69
213.57
iu/ml
—
13
7
77
54
18.60
88.40
3.7
2.9
—
—
—
0
0
55
18
36.88
85.64
3.2
2.0
39.25
45.14
%
—
44
8
76
57
17.31
84.02
2.6
1.8
—
—
—
0
0
76
58
17.00
83.19
2.7
1.8
—
—
—
0
0
87
93
12.59
77.15
3.4
1.5
—
—
—
0
0
51
20
30.29
74.67
3.5
1.1
—
—
—
0
0
51
21
28.84
73.37
3.5
1.1
—
—
—
0
0
86
97
11.86
73.28
2.0
1.4
1.23
1.19
g/l
0.36
77
92
104
151
9.83
73.16
3.1
1.5
—
—
—
0
0
67
55
15.24
69.91
1.8
1.2
—
—
—
0
0
58
37
19.03
69.26
2.4
1.9
—
—
—
0
0
58
37
19.03
69.26
2.4
1.9
—
—
—
0
0
141
320
7.21
65.33
3.8
1.9
—
—
—
0
0
58
43
16.34
63.91
2.2
1.6
—
—
—
0
0
277
1214
12.43
63.23
26.9
5.9
2.61
2.85
%
1.20
277
1144
115
223
7.58
61.84
3.2
1.7
—
—
—
0
0
45
21
24.87
61.49
5.0
2.4
—
—
—
0
0
277
1252
11.81
59.91
25.7
5.8
57.86
56.24
%
1.40
277
1186
278
1267
11.96
59.41
27.1
6.0
28.28
29.47
%
0.94
278
1203
110
225
7.01
55.61
3.6
1.7
—
—
—
0
0
52
41
15.02
55.10
2.7
2.0
—
—
—
0
0
41
20
23.45
54.88
5.2
2.5
—
—
—
0
0
37
20
20.85
47.24
1.7
1.9
—
—
—
0
0
44
34
14.90
46.95
2.6
1.6
—
—
—
0
0
43
0
+∞
45.98
2.0
0.0
1.84
—
mg/l
—
23
0
43
0
+∞
45.98
2.0
0.0
1.09
—
mg/l
—
26
0
43
0
+∞
45.98
2.0
0.0
0.84
—
mg/l
—
29
0
43
0
+∞
45.98
2.0
0.0
2.62
—
mg/l
—
27
0
43
0
+∞
45.98
2.0
0.0
0.74
—
mg/l
—
25
0
43
0
+∞
45.98
2.0
0.0
0.40
—
mg/l
—
28
0
43
0
+∞
45.98
2.0
0.0
0.94
—
mg/l
—
29
0
43
0
+∞
45.98
2.0
0.0
1.01
—
mg/l
—
27
0
43
0
+∞
45.98
2.0
0.0
0.73
—
mg/l
—
24
0
43
0
+∞
45.98
2.0
0.0
3.09
—
mg/l
—
26
0
114
292
5.58
44.31
3.2
2.5
21.70
23.98
%
0.73
100
252
38
26
16.50
43.23
2.4
1.7
—
—
—
0
0
38
26
16.50
43.23
2.4
1.7
—
—
—
0
0
49
53
10.78
42.09
3.4
1.4
—
—
—
0
0
37
26
16.01
41.47
2.4
1.8
—
—
—
0
0
44
43
11.75
40.48
2.2
1.5
—
—
—
0
0
41
37
12.61
39.70
2.4
1.6
—
—
—
0
0
39
34
12.97
38.56
2.2
1.8
—
—
—
0
0
42
45
10.63
36.17
1.9
2.1
122.67
133.73
g/l
—
9
33
47
62
8.75
34.53
3.9
1.9
1.33
1.02
ug/l
0.21
42
57
92
239
5.04
34.32
3.2
1.9
335.22
365.78
nmol/l
0.77
85
223
297
1877
13.11
33.41
24.4
7.2
89.90
77.93
u/l
5.27
297
1771
34
30
12.60
33.24
2.7
1.7
—
—
—
0
0
218
1095
4.29
32.39
18.9
7.2
1.21
1.22
mmol/l
0.34
192
941
297
1899
12.73
32.35
16.9
3.8
12.36
9.73
mm/h
2.77
292
1764
41
51
9.10
31.48
2.0
1.5
—
—
—
0
0
200
990
3.84
29.34
20.3
6.5
1.21
1.22
mmol/l
2.32
193
913
109
360
4.12
29.31
2.3
2.6
189.80
107.72
ug/g
1.05
95
294
31
30
11.36
28.46
4.6
1.5
—
—
—
0
0
38
49
8.69
28.28
9.0
3.7
55.39
55.98
%
0.07
38
49
30
28
11.75
28.20
1.4
1.3
—
—
—
0
0
31
31
10.99
27.83
4.6
1.5
—
—
—
0
0
31
31
10.99
27.83
4.6
1.5
—
—
—
0
0
31
31
10.99
27.83
4.6
1.5
—
—
—
0
0
31
31
10.99
27.83
4.6
1.5
—
—
—
0
0
31
31
10.99
27.83
4.6
1.5
—
—
—
0
0
32
6
59.16
27.75
1.1
1.0
95.69
92.00
%
—
32
6
46
78
6.74
26.89
2.0
2.6
1.31
1.39
g/l
0.17
36
69
39
59
7.41
25.29
1.5
1.3
2.31
0.92
u/ml
—
9
5
43
77
6.32
23.75
4.0
2.4
—
—
—
0
0
50
105
5.48
23.37
1.6
1.3
0.53
3.46
u/ml
—
8
8
165
804
3.23
23.16
6.1
3.0
—
—
—
0
0
34
50
7.51
22.55
2.2
2.0
—
—
—
0
0
31
41
8.28
22.49
1.8
1.3
—
—
—
0
0
31
41
8.28
22.49
1.8
1.3
—
—
—
0
0
49
109
5.15
21.40
2.2
1.4
—
—
—
0
0
34
54
6.94
21.01
1.6
1.4
94.54
108.38
u/ml
—
13
8
27
9
32.66
20.93
1.5
1.4
—
—
—
0
0
31
17
20.09
20.88
1.1
7.7
—
42.17
u/ml
—
0
6
177
938
3.05
20.79
15.2
9.1
1.04
1.15
inr
3.16
57
294
37
65
6.32
20.76
1.4
1.5
383.68
271.25
ug/g
2.76
31
42
45
96
5.31
20.59
2.0
2.2
—
—
—
0
0
28
37
8.22
20.28
1.5
1.4
—
—
—
0
0
66
197
3.98
19.79
14.4
4.6
1.84
2.15
mmol/l
0.33
60
154
219
1362
3.04
18.28
15.9
4.8
6.42
6.49
mmol/l
0.21
213
1259
132
631
2.89
18.15
5.3
2.8
0.28
0.39
e6/l
0.36
115
470
136
661
2.87
18.12
4.7
2.1
120.35
254.59
u/l
0.75
130
632
33
60
6.03
17.84
1.6
1.3
25.12
49.08
u/ml
—
10
6
37
78
5.25
17.07
1.6
1.3
1.61
6.41
u/ml
—
8
19
85
329
3.18
16.89
4.1
2.2
30.11
29.68
s
0.25
78
322
120
573
2.78
16.19
2.9
1.8
1.05
0.98
mg/l
0.17
105
422
36
78
5.09
16.09
1.6
1.3
3.22
3.21
u/ml
—
6
12
26
19
14.81
15.81
2.3
2.2
—
—
—
0
0
26
19
14.81
15.81
2.3
2.2
—
—
—
0
0
26
19
14.81
15.81
2.3
2.2
—
—
—
0
0
21
8
27.99
15.80
1.5
1.1
—
—
—
0
0
21
8
27.99
15.80
1.5
1.1
—
—
—
0
0
23
33
7.44
15.47
1.6
1.1
—
—
—
0
0
85
345
3.01
15.42
1.8
1.6
1372.99
1133.88
nmol/l
1.37
74
256
107
496
2.76
15.13
5.1
2.6
1621.73
643.86
ng/l
0.72
97
391
25
19
14.19
14.97
4.6
3.2
—
—
—
0
0
58
195
3.43
14.34
29.0
11.2
11.35
12.53
kpa
0.97
51
186
58
195
3.43
14.34
29.1
11.2
5.02
5.13
kpa
0.40
52
185
25
22
12.25
14.06
2.2
1.1
1.02
0.34
u/ml
—
16
10
39
101
4.27
13.99
35.3
15.7
—
—
—
0
0
21
13
17.21
13.65
1.8
1.2
—
—
—
0
0
30
64
5.08
13.61
1.6
1.3
—
—
—
0
0
104
498
2.63
13.58
2.2
1.4
22.09
22.31
nmol/l
0.05
98
429
57
196
3.33
13.57
29.8
11.2
0.89
1.37
mmol/l
0.34
43
155
192
1221
2.49
13.55
6.7
4.4
0.00
0.00
estimate
0.50
52
240
305
2628
8.15
13.34
54.7
11.5
15.89
20.21
mg/l
3.43
300
1984
45
134
3.76
13.32
5.8
2.3
210.98
113.00
ng/l
0.44
40
118
32
74
4.70
13.21
6.6
1.9
—
—
—
0
0
20
12
17.70
13.16
2.6
2.3
—
—
—
0
0
20
12
17.70
13.16
2.6
2.3
—
—
—
0
0
22
17
13.82
13.13
4.0
1.4
24.45
30.47
umol/l
1.17
22
17
190
1221
2.42
12.83
5.5
3.2
0.00
0.00
estimate
0.50
53
251
191
1235
2.41
12.65
5.5
3.2
0.00
0.01
estimate
0.50
51
230
26
53
5.26
12.39
3.6
1.5
4.48
8.47
e6/l
0.29
21
38
303
2614
6.51
12.37
50.8
12.4
139.42
139.70
mmol/l
1.35
303
2546
19
12
16.76
12.30
3.2
1.3
—
—
—
0
0
303
2626
6.33
11.99
51.2
12.5
3.91
3.94
mmol/l
1.51
303
2552
17
9
19.89
11.72
2.8
2.8
—
—
—
0
0
17
9
19.89
11.72
2.8
2.8
—
—
—
0
0
17
9
19.89
11.72
2.8
2.8
—
—
—
0
0
31
77
4.36
11.70
1.5
1.1
—
—
—
0
0
91
437
2.53
11.57
2.0
1.7
494.86
17867109.22
pmol/l
0.50
85
375
24
29
8.87
11.53
1.6
1.1
—
—
—
0
0
20
17
12.48
11.50
1.1
1.1
—
—
—
0
0
62
246
2.90
11.47
18.1
7.8
104.50
104.19
mmol/l
0.22
62
246
55
205
3.04
11.36
5.0
3.1
—
—
—
0
0
143
845
2.28
11.31
2.6
1.8
89.25
97.88
pmol/l
1.53
93
427
16
8
20.98
11.25
1.2
2.3
—
—
iu/ml
—
0
0
70
300
2.72
11.18
5.3
2.7
8.16
6.46
umol/l
0.28
63
266
36
104
3.78
11.09
27.0
11.7
25.29
24.91
mmol/l
0.25
31
97
135
786
2.26
10.99
6.0
3.1
2.30
2.35
mmol/l
3.99
129
690
30
77
4.20
10.85
1.5
1.4
0.01
0.02
iu/ml
—
7
14
87
421
2.48
10.80
5.9
3.1
203.42
265.28
ng/l
0.22
59
276
20
20
10.60
10.67
2.9
1.6
—
—
—
0
0
43
144
3.30
10.59
7.9
3.4
0.84
1.66
mmol/l
0.60
33
97
24
53
4.82
10.43
7.6
4.5
23.15
30.41
mg/l
0.35
18
44
24
53
4.82
10.43
7.6
4.5
18.28
156.15
mg/l
0.65
17
45
17
14
12.76
9.97
1.1
1.2
—
—
—
0
0
110
608
2.25
9.97
6.1
2.8
316.82
4682.09
umol/l
1.95
105
538
20
24
8.82
9.71
1.3
1.2
—
—
—
0
0
43
153
3.10
9.57
8.0
3.4
4.91
5.12
kpa
1.40
38
147
35
111
3.43
9.37
2.6
1.7
—
—
—
0
0
18
20
9.48
9.16
2.1
1.2
—
—
—
0
0
13
7
19.30
9.01
1.3
1.1
—
—
—
0
0
112
649
2.13
8.84
6.8
3.4
0.00
0.01
estimate
0.80
52
236
149
963
2.05
8.74
5.7
3.2
—
—
—
0
0
17
19
9.39
8.65
2.1
1.2
—
—
—
0
0
17
19
9.39
8.65
1.1
1.7
—
—
—
0
0
12
6
20.72
8.53
1.8
1.5
—
—
—
0
0
27
77
3.74
8.45
4.2
2.2
—
—
—
0
0
42
160
2.88
8.27
3.3
3.6
4.14
4.59
pmol/l
2.68
37
142
27
79
3.65
8.15
1.9
1.2
—
—
—
0
0
282
2370
2.97
7.99
56.9
14.2
14.62
14.31
%
0.74
282
2344
17
22
8.10
7.98
1.5
1.1
—
—
—
0
0
87
475
2.15
7.87
1.4
1.3
27.08
34.96
iu/ml
0.35
25
167
14
14
10.41
7.61
3.4
1.9
—
—
—
0
0
14
14
10.41
7.61
1.6
1.5
—
—
—
0
0
162
1121
1.93
7.44
5.0
2.5
—
—
—
0
0
15
18
8.69
7.40
3.6
1.7
4.23
4.78
mg/l
0.14
15
18
14
15
9.71
7.36
3.4
1.8
—
—
—
0
0
16
23
7.27
7.09
1.2
1.1
—
—
—
0
0
11
8
14.19
6.94
1.1
1.0
—
—
—
0
0
83
468
2.05
6.80
1.4
1.3
2.29
8.58
u/ml
2.04
31
198
11
9
12.61
6.63
3.2
1.9
83.64
57.14
ug/l
—
11
9
13
15
8.99
6.62
3.6
1.8
—
—
—
0
0
28
96
3.11
6.61
14.8
3.2
0.54
0.64
%
0.83
28
96
67
353
2.14
6.54
3.8
2.7
3.65
2.80
e6/l
0.39
38
180
11
10
11.35
6.34
1.1
1.1
1470.09
1831.30
miu/ml
—
11
10
6
0
+∞
6.27
1.3
0.0
—
—
—
0
0
14
21
6.92
6.10
3.6
1.3
32.07
32.71
pg
0.17
14
21
67
364
2.07
6.01
3.4
2.6
1.08
0.83
e6/l
0.27
37
190
11
12
9.45
5.83
1.9
2.6
—
—
—
0
0
11
12
9.45
5.83
1.9
2.6
—
—
—
0
0
14
23
6.32
5.76
1.0
1.1
—
—
—
0
0
119
797
1.80
5.65
5.4
3.0
111.07
30.32
ng/l
0.45
75
441
24
83
3.05
5.60
6.1
4.0
62.45
53.51
%
0.84
24
83
10
10
10.28
5.57
1.6
1.2
—
—
—
0
0
15
29
5.38
5.46
1.8
1.3
—
—
—
0
0
89
559
1.83
5.15
4.0
2.2
—
—
—
0
0
10
13
7.90
4.88
2.8
4.2
—
—
—
0
0
10
13
7.90
4.88
1.1
1.1
—
—
—
0
0
13
25
5.38
4.82
1.1
1.1
—
—
—
0
0
15
34
4.58
4.81
2.9
1.9
1.67
1.71
mmol/l
0.05
15
34
47
244
2.09
4.71
2.9
2.5
32.12
27.20
u/l
0.37
42
205
275
2426
2.13
4.57
34.7
10.6
91.35
88.66
ml/min/173m2
1.26
260
1976
13
27
4.98
4.55
2.8
1.8
90.20
90.92
%
0.20
13
27
13
27
4.98
4.55
1.2
1.1
—
—
—
0
0
11
19
5.96
4.48
1.4
1.0
—
—
—
0
0
13
28
4.80
4.42
1.2
1.1
—
—
—
0
0
8
9
9.08
4.30
1.4
1.1
52.00
14.41
u/l
—
8
9
8
11
7.43
3.88
1.8
1.5
—
—
—
0
0
8
11
7.43
3.88
1.8
1.5
—
—
—
0
0
238
2040
1.70
3.88
5.2
3.9
14.86
14.48
pmol/l
1.58
228
1893
302
2809
3.34
3.86
32.8
9.4
30.87
27.42
u/l
2.47
302
2725
94
647
1.65
3.79
1.8
1.6
—
—
—
0
0
9
16
5.76
3.68
4.2
2.3
—
—
—
0
0
14
40
3.62
3.65
4.8
2.6
15.77
17.02
%
—
9
20
7
9
7.92
3.57
1.7
1.0
—
—
—
0
0
7
9
7.92
3.57
1.3
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
10
7.13
3.38
1.4
1.2
—
—
—
0
0
222
1899
1.59
3.34
5.8
3.0
53.03
43.06
u/l
1.96
217
1809
10
23
4.46
3.34
1.3
1.3
—
—
—
0
0
10
23
4.46
3.34
1.3
1.3
—
—
—
0
0
9
19
4.84
3.26
1.2
1.5
2.44
5.71
u/field
—
9
7
10
24
4.27
3.22
1.3
1.3
—
—
—
0
0
10
24
4.27
3.22
1.4
1.2
—
—
—
0
0
10
24
4.27
3.22
1.3
1.3
—
—
—
0
0
10
24
4.27
3.22
1.3
1.3
—
—
—
0
0
7
11
6.48
3.20
2.3
1.2
4.20
5.94
umol/l
—
7
11
14
50
2.88
3.13
1.3
1.1
—
—
—
0
0
26
127
2.14
3.07
1.1
1.4
336.63
253.86
miu/ml
0.44
12
61
268
2420
1.76
3.07
6.0
4.6
1.86
1.80
mu/l
0.36
263
2262
6
8
7.62
3.07
1.0
1.0
—
—
—
0
0
35
192
1.93
3.03
2.5
2.3
62.75
71.91
ml/min/173m2
0.51
16
81
5
5
10.13
2.99
1.0
6.8
—
—
—
0
0
5
5
10.13
2.99
2.2
1.0
—
—
—
0
0
5
5
10.13
2.99
1.2
1.0
—
—
—
0
0
8
18
4.53
2.81
3.3
3.2
94.50
99.56
%
—
8
18
14
54
2.67
2.74
2.3
1.1
88.29
10.58
iu/ml
—
7
12
14
54
2.67
2.74
1.2
1.2
1.50
1.53
u/ml
—
6
15
13
301
0.41
2.71
1.5
1.7
—
—
—
0
0
33
185
1.88
2.69
1.7
1.3
—
33.73
—
0
11
11
35
3.22
2.67
1.4
1.1
—
—
—
0
0
232
2046
1.52
2.67
4.7
3.5
—
—
—
0
0
12
41
3.00
2.65
1.5
1.3
268.07
12.99
u/l
0.56
12
36
7
17
4.19
2.37
3.1
3.3
—
—
—
0
0
9
28
3.28
2.32
1.0
1.0
—
—
—
0
0
88
670
1.44
2.11
1.4
1.4
0.53
1.74
u/ml
2.63
16
184
11
43
2.61
2.10
1.8
1.9
7.66
9.00
umol/l
0.08
11
29
53
366
1.54
2.05
2.9
2.7
2.45
2.43
mmol/l
0.66
46
312
6
15
4.06
2.05
1.2
2.1
8.43
10.53
umol/l
—
6
15
6
15
4.06
2.05
2.2
1.4
—
—
—
0
0
11
44
2.55
2.03
1.5
1.3
—
—
—
0
0
35
219
1.67
2.02
1.9
1.2
75.81
147.54
iu/ml
0.86
16
87
13
57
2.34
2.00
1.2
1.2
2.40
3.48
u/ml
—
5
25
5
11
4.60
1.95
1.0
1.5
—
—
—
0
0
5
11
4.60
1.95
1.0
1.5
—
—
—
0
0
17
85
2.06
1.94
1.7
1.2
—
—
—
0
0
17
86
2.03
1.89
1.7
1.2
—
—
—
0
0
8
28
2.90
1.87
1.3
2.9
7.89
3.01
nmol/l
—
8
28
13
60
2.22
1.80
1.5
1.2
—
—
—
0
0
20
110
1.87
1.77
1.5
1.3
—
—
—
0
0
19
103
1.90
1.76
1.8
1.4
—
—
—
0
0
31
198
1.63
1.67
2.7
2.0
—
—
—
0
0
6
24
2.53
1.31
1.2
1.7
—
—
—
0
0
16
265
0.58
1.30
15.4
5.5
—
—
—
0
0
5
118
0.41
1.27
1.4
1.4
—
—
—
0
0
245
2591
0.75
1.27
4.0
4.0
4.62
4.79
mmol/l
1.79
236
2442
5
19
2.66
1.22
1.0
1.9
0.99
0.98
g/l
—
5
19
20
127
1.61
1.14
2.1
2.1
623.67
4225.79
u/l
—
6
48
8
41
1.98
1.09
2.4
2.0
—
—
—
0
0
19
121
1.61
1.08
4.4
2.7
0.28
0.09
e6/l
0.70
19
116
306
2998
2.08
1.07
67.5
17.1
131.47
137.15
g/l
8.91
306
2960
306
2997
2.09
1.07
67.1
17.0
4.48
4.56
e12/l
1.67
306
2927
306
2995
2.13
1.07
67.3
17.0
237.99
257.48
e9/l
3.52
306
2925
306
2995
2.13
1.07
69.3
17.0
39.69
40.83
%
3.89
289
2828
16
98
1.67
1.05
1.4
1.7
—
—
—
0
0
51
399
1.33
1.04
2.5
2.0
—
—
—
0
0
236
2491
0.78
1.03
3.8
3.6
1.42
1.28
mmol/l
1.88
229
2325
251
2621
0.78
0.91
4.3
4.4
2.75
2.89
mmol/l
1.53
241
2455
10
56
1.81
0.89
1.1
1.1
—
—
—
0
0
247
2582
0.79
0.88
3.8
4.0
1.41
1.48
mmol/l
1.84
237
2420
23
164
1.43
0.82
2.0
2.4
47.48
48.91
u/ml
0.02
23
157
33
252
1.35
0.81
2.9
2.0
—
—
—
0
0
53
433
1.27
0.81
2.7
2.1
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
0
27
0.00
0.78
0.0
1.3
—
—
—
0
0
75
650
1.20
0.67
4.0
3.8
23.05
11.82
mg/mmol
0.29
48
398
5
28
1.80
0.66
1.4
3.2
74.04
52.30
u/ml
—
5
28
5
85
0.58
0.46
1.6
1.6
—
—
—
0
0
21
169
1.26
0.40
1.6
1.3
—
—
—
0
0
11
148
0.73
0.39
1.5
1.5
—
—
—
0
0
49
433
1.16
0.37
3.0
3.7
19.25
23.04
%
0.77
21
159
38
330
1.17
0.36
2.7
2.6
0.71
0.69
ug/l
0.04
29
182
5
79
0.63
0.36
1.2
1.4
—
—
—
0
0
5
79
0.63
0.36
1.2
1.4
—
—
—
0
0
5
79
0.63
0.36
1.2
1.4
—
—
—
0
0
7
57
1.23
0.29
2.4
1.9
—
—
—
0
0
244
2486
0.92
0.23
4.6
4.0
5.74
5.77
mmol/l
0.13
238
2309
5
42
1.19
0.21
2.2
1.8
13.76
13.25
%
—
5
42
74
700
1.07
0.18
1.6
1.7
1.36
1.42
mmol/l
0.28
69
606
7
60
1.17
0.18
2.1
1.7
—
—
—
0
0
54
506
1.08
0.17
1.6
1.4
—
—
—
0
0
228
2319
0.94
0.17
5.5
5.0
37.75
38.76
mmol/mol
0.81
222
2191
8
71
1.13
0.16
1.3
1.7
213.38
244.87
pmol/l
—
8
64
43
401
1.08
0.15
1.7
1.9
1.68
1.39
%
0.79
37
367
14
159
0.87
0.13
1.1
1.0
—
—
—
0
0
8
74
1.08
0.07
1.9
1.5
—
—
—
0
0
12
130
0.92
0.04
1.5
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
66.52
—
0
5
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
10
100
1.00
-0.00
1.7
1.4
—
—
—
0
0
5
54
0.92
-0.00
1.8
1.5
—
—
—
0
0
6
61
0.98
-0.00
3.0
2.2
0.68
0.82
nmol/l
—
6
52
Mortality – FinRegistry
↥Association
Association between endpoint D3_KELA_IMMUDEF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_KELA_IMMUDEF | 5.013 [3.21, 7.83] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.595 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 416 females with D3_KELA_IMMUDEF died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have D3_KELA_IMMUDEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.44% | No data |
| 5 | 3.202% | No data |
| 10 | 7.618% | No data |
| 15 | 14.22% | No data |
| 20 | 23.763% | No data |
Relationships between endpoints
↥Index endpoint: D3_KELA_IMMUDEF – Kela reimbursement Agammaglobulinemia (D80-84)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data