No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
300 |
4. Check minimum number of eventsNone |
300 |
5. Include endpointsNone |
300 |
6. Filter based on genotype QC (FinnGen only) |
300 |
Control definitions (FinnGen only)
- Control exclude
- D3_IMMUNEMECHANISM
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Kela reimbursement Agammaglobulinemia (D80-84)
based on the number of shared cases.
Similar with more cases:
- Immunodeficiencies
- Certain disorders involving the immune mechanism
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any reimbursement code in KELA
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 979 | 566 | 411 |
| Only index persons | 863 | 510 | 353 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 42.67 | 45.86 | 38.29 |
| Only index persons | 41.96 | 46.26 | 35.76 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 300 | 193 | 107 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.05 |
| Median age at first event (years) | 44.08 | 45.84 | 40.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 258
- Matched controls
- 2578
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
120
Kela drug reimbursment
Hypogammaglobulinaemia
+∞
323.0
258
*
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
+∞
294.4
223
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
+∞
188.4
157
*
ZX120
NOMESCO Finland
Intravenous
26.7
93.4
139
108
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
+∞
91.2
82
*
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
+∞
88.8
80
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
49.4
80.5
97
31
6BA02
NOMESCO Finland
NA
324.5
73.5
71
*
J01MA12
ATC
levofloxacin; systemic
13.1
68.1
143
224
D80.3
ICD-10 Finland
Selective deficiency of immunoglobulin G [IgG] subclasses
+∞
67.7
62
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
29.7
64.2
88
44
WW200
NOMESCO Finland
Immunization
47.5
62.0
75
22
J01MA14
ATC
moxifloxacin; systemic
18.5
61.1
100
85
D80.0
ICD-10 Finland
Hereditary hypogammaglobulinaemia
+∞
59.7
55
*
D83.0
ICD-10 Finland
Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
+∞
58.6
54
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
15.5
57.5
102
104
J18.9
ICD-10 Finland
Pneumonia, unspecified
10.0
56.3
138
266
J47
ICD-10 Finland
Bronchiectasis
108.5
55.6
59
7
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
39.6
54.1
68
23
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
43.8
53.7
66
20
D83.9
ICD-10 Finland
Common variable immunodeficiency, unspecified
+∞
51.8
48
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.9
50.6
189
664
TPH04
NOMESCO Finland
Cathetrisation of vein
8.6
50.0
135
292
TDM10
NOMESCO Finland
Puncture of maxillary antrum
22.6
49.9
74
45
C01CA24
ATC
epinephrine; parenteral
15.3
48.6
85
80
H02AB06
ATC
prednisolone; systemic
7.3
45.4
198
803
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
13.8
43.3
79
80
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.8
42.8
106
190
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
6.6
40.9
138
382
J01.0
ICD-10 Finland
Acute maxillary sinusitis
6.7
40.4
133
355
Z01.8
ICD-10 Finland
Other specified special examinations
6.4
37.0
121
312
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
12.4
36.0
68
72
R50.9
ICD-10 Finland
Fever, unspecified
7.2
34.2
95
193
UDH02
NOMESCO Finland
Rhinopharyngoscopy
11.1
32.5
65
76
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
12.7
32.4
60
60
UGC12
NOMESCO Finland
Flexible bronchoscopy
13.5
32.3
58
54
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
6.2
31.8
101
242
TGC00
NOMESCO Finland
Bronchial lavation
36.1
31.4
40
13
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
17.8
29.1
46
31
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
4.8
28.3
197
1043
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.7
28.2
126
432
SPAT1262
SPAT
Handing over of treatment supplies
5.7
27.2
90
220
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
10.8
26.7
53
60
J01FA06
ATC
roxithromycin; oral
4.3
26.6
160
715
J01MA02
ATC
ciprofloxacin; systemic
4.3
26.0
136
530
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
275.6
25.1
25
*
J45.1
ICD-10 Finland
Nonallergic asthma
8.4
25.0
58
86
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.4
25.0
58
86
J01FA10
ATC
azithromycin; systemic
4.5
23.8
211
1282
J01FA15
ATC
telithromycin; oral
6.0
22.9
69
147
R03BB04
ATC
tiotropium bromide; inhalant
8.7
22.7
51
71
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
8.7
22.4
50
69
D83.8
ICD-10 Finland
Other common variable immunodeficiencies
+∞
22.2
21
*
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
88.0
22.1
24
*
D80.2
ICD-10 Finland
Selective deficiency of immunoglobulin A [IgA]
239.5
21.9
22
*
R01AD09
ATC
mometasone; nasal
3.7
21.8
171
897
J45.9
ICD-10 Finland
Asthma, unspecified
4.6
21.4
88
263
J01FF01
ATC
clindamycin; systemic
3.9
21.2
114
435
J45.0
ICD-10 Finland
Predominantly allergic asthma
6.1
21.1
62
127
GD1AD
NOMESCO Finland
Thorax CT examination
13.3
21.0
37
32
J01AA02
ATC
doxycycline; systemic
5.1
20.8
229
1573
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
6.6
20.8
57
106
R03AC02
ATC
salbutamol; inhalant
3.7
20.7
185
1055
H02AB07
ATC
prednisone; oral
5.0
20.5
74
192
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
8.2
20.4
47
68
A07AA02
ATC
nystatin; oral
9.1
19.5
42
54
R03AK06
ATC
salmeterol and fluticasone; inhalant
5.3
19.5
65
154
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.1
19.2
90
300
B29
ICPC
Lymph/immune mech sympt/complt other
75.7
19.0
21
*
ZXA10
NOMESCO Finland
Bilateral
4.3
18.9
82
254
XW000
NOMESCO Finland
Bone marrow biopsy
11.1
18.9
36
37
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
16.0
18.6
30
21
UJF30
NOMESCO Finland
Ileoscopy through colon
6.0
18.4
54
109
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
9.2
18.3
39
49
A41.9
ICD-10 Finland
Sepsis, unspecified
16.2
18.1
29
20
TAB00
NOMESCO Finland
Lumbar puncture
9.4
17.7
37
45
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.2
17.6
172
989
R03DC03
ATC
montelukast; oral
3.9
17.6
85
288
J01FA09
ATC
clarithromycin; systemic
3.3
17.5
125
575
JN4BD
NOMESCO Finland
Extensive body CT
5.3
17.3
56
127
H04.10
ICD-10 Finland
Dry eye syndrome
5.6
17.3
53
113
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
53.9
17.2
20
*
J05AB01
ATC
aciclovir; systemic
3.8
17.1
85
294
J46
ICD-10 Finland
Status asthmaticus
14.8
16.9
28
21
J06BA02
ATC
immunoglobulins, normal human, for intravascular adm.; systemic
+∞
16.9
16
*
M36.8*D80.1
ICD-10 Finland
Systemic disorders of connective tissue in hypogammaglobulinaemia
+∞
16.9
16
*
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
96.4
16.8
18
*
J32.4
ICD-10 Finland
Chronic pansinusitis
15.9
16.2
26
18
R03BA02
ATC
budesonide; inhalant
3.8
16.2
78
261
D84.18
ICD-10 Finland
Other specified defect in the complement system
+∞
15.8
15
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
15.8
60
161
J05AB11
ATC
valaciclovir; oral
4.3
15.7
64
184
WZC30
NOMESCO Finland
Teaching
4.3
15.7
64
184
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
9.5
15.5
32
38
R01AD08
ATC
fluticasone; nasal
3.1
15.4
115
534
J02AC01
ATC
fluconazole; systemic
3.0
15.4
141
747
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.7
15.1
45
92
WX408
NOMESCO Finland
General anesthesy, balanced
3.1
14.8
105
465
XQ800
NOMESCO Finland
Prick test
5.4
14.8
46
99
R03BB01
ATC
ipratropium bromide; inhalant
13.7
14.7
25
20
D80.6
ICD-10 Finland
Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
+∞
14.7
14
*
XF400
NOMESCO Finland
ECG with 12 standard connections
4.0
14.7
66
206
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
7.8
14.7
34
49
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
38.5
14.6
18
5
UJF32
NOMESCO Finland
Coloscopy
3.4
14.6
83
314
ZX110
NOMESCO Finland
Intracutaneous
158.6
14.6
15
*
XG410
NOMESCO Finland
Flow-volume spirometry
8.1
14.6
33
46
R05
ICD-10 Finland
Cough
3.5
14.5
77
276
C03CA01
ATC
furosemide; systemic
3.8
14.3
67
217
N03AX16
ATC
pregabalin; oral
3.3
14.1
84
328
B28
ICPC
Limited function/disability (B)
56.6
14.0
16
*
H02AB09
ATC
hydrocortisone; systemic
9.2
14.0
29
35
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
79.5
13.7
15
*
L03AA02
ATC
filgrastim; parenteral
11.4
13.6
25
24
J31.0
ICD-10 Finland
Chronic rhinitis
5.5
13.6
41
85
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
22.7
13.5
19
9
J01DB01
ATC
cefalexin; oral
4.2
13.4
235
1829
ZX121
NOMESCO Finland
Central venous catheter
42.5
13.3
16
*
A01AB09
ATC
miconazole; local oral
5.5
13.2
40
83
N02AX02
ATC
tramadol; systemic, rectal
2.7
13.1
126
667
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.4
13.1
35
62
ZX108
NOMESCO Finland
Inhalation
24.0
13.1
18
8
R03BA08
ATC
ciclesonide; inhalant
4.5
13.0
48
124
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.2
12.8
35
64
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
4.0
12.7
54
159
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
33.9
12.7
16
5
GD1CG
NOMESCO Finland
Extensive examination of lungs and pleura with high intensity magnet
73.6
12.7
14
*
R03DA04
ATC
theophylline; systemic, rectal
8.7
12.7
27
34
R4110
NOMESCO Finland
Physiotherapy
2.9
12.6
95
430
D84.9
ICD-10 Finland
Immunodeficiency, unspecified
+∞
12.6
12
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.7
12.5
114
577
R01AD05
ATC
budesonide; nasal
4.7
12.5
44
108
M05BA04
ATC
alendronic acid; oral
6.1
12.3
34
63
R03AC12
ATC
salmeterol; inhalant
7.7
12.2
28
40
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.8
12.2
99
468
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
14.3
12.2
20
15
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.9
12.1
52
155
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
8.4
12.0
26
34
A02BC03
ATC
lansoprazole; oral
2.9
11.9
91
412
N02AA05
ATC
oxycodone; systemic
4.0
11.7
49
142
J45.8
ICD-10 Finland
Mixed asthma
9.0
11.6
24
29
J01DA06
ATC
[U] cefuroxime; systemic
3.4
11.5
61
213
Z31.5
ICD-10 Finland
Genetic counselling
5.1
11.3
36
79
GD1DG
NOMESCO Finland
Extremely extensive MRI examination of pleura with high field magnet
45.4
11.0
13
*
P01AB01
ATC
metronidazole; oral, rectal
2.5
11.0
123
689
R06AE07
ATC
cetirizine; oral
2.5
11.0
146
893
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
18.8
10.9
16
9
ZXA00
NOMESCO Finland
Right side
2.8
10.8
85
389
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.5
10.7
113
609
J01DA01
ATC
[U] cefalexin; systemic
2.5
10.6
180
1241
D83.1
ICD-10 Finland
Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
+∞
10.5
10
*
SPAT1255
SPAT
Intravenous administration of medicine
5.5
10.5
31
63
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
19.8
10.4
15
8
H02AB04
ATC
methylprednisolone; systemic
3.3
10.3
56
199
ZXA05
NOMESCO Finland
Left side
2.8
10.3
78
346
C10AC01
ATC
colestyramine; oral
13.9
10.3
17
13
R03BA05
ATC
fluticasone; inhalant
2.9
10.2
69
284
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
8.2
10.1
22
29
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
41.8
10.1
12
*
R06.0
ICD-10 Finland
Dyspnoea
2.8
10.0
74
323
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.5
9.9
49
163
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
21.0
9.9
14
7
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
14.1
9.8
16
12
XA800
NOMESCO Finland
Neuropsychological investigation
5.2
9.7
30
64
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
6.0
9.7
26
47
UDQ12
NOMESCO Finland
Flexible laryngoscopy
5.7
9.5
27
52
WX882
NOMESCO Finland
High dependency care
8.6
9.5
20
25
R03BA01
ATC
beclometasone; inhalant
3.1
9.5
56
210
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.3
9.5
35
90
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
31.3
9.5
12
*
4730A
ICD-9 Finland
Chronic sinusitis, Maxillary
11.3
9.4
17
16
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.1
9.4
18
19
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
14.4
9.3
15
11
A46
ICD-10 Finland
Erysipelas
3.7
9.3
42
130
A03FA01
ATC
metoclopramide; systemic, rectal
2.7
9.2
72
322
R03AC13
ATC
formoterol; inhalant
5.2
9.2
28
59
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.0
9.2
56
217
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
38.1
9.1
11
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.9
9.1
58
231
WW500
NOMESCO Finland
Blood transfusion
7.3
9.0
21
31
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
6.8
9.0
22
35
50301
ICD-8 Finland
Chronic sinusitis, Maxillaris NUD
25.1
9.0
12
5
A07AA09
ATC
vancomycin; oral
25.1
9.0
12
5
J01.4
ICD-10 Finland
Acute pansinusitis
25.1
9.0
12
5
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
8.9
68
299
ZX114
NOMESCO Finland
Intramuscular
10.0
8.9
17
18
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.8
8.8
60
249
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
8.7
8.7
18
22
A02BC02
ATC
pantoprazole; systemic
2.2
8.7
167
1162
M04AA01
ATC
allopurinol; systemic
3.9
8.7
36
103
E0000UV
ATC
NA
2.2
8.7
121
728
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.5
8.6
41
132
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.2
8.6
48
174
A02BC01
ATC
omeprazole; systemic
2.5
8.6
76
366
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
28.6
8.6
11
*
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
20.9
8.5
12
6
ZX112
NOMESCO Finland
Subcutaneous
8.3
8.5
18
23
R01AD12
ATC
fluticasone furoate; nasal
2.3
8.5
104
588
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.8
8.5
61
260
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
8.4
105
598
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.5
8.4
40
129
2790B
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI A]
+∞
8.4
8
*
D81.0
ICD-10 Finland
Severe combined immunodeficiency [SCID] with reticular dysgenesis
+∞
8.4
8
*
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
+∞
8.4
8
*
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
+∞
8.4
8
*
D84.19
ICD-10 Finland
Unspecified defect in the complement system
+∞
8.4
8
*
D86.0
ICD-10 Finland
Sarcoidosis of lung
+∞
8.4
8
*
WX002
NOMESCO Finland
Sedation and analgesia
2.7
8.3
60
256
R01AD01
ATC
beclometasone; nasal
2.8
8.3
55
224
H65.2
ICD-10 Finland
Chronic serous otitis media
15.1
8.3
13
9
A41.8
ICD-10 Finland
Other specified sepsis
15.1
8.3
13
9
B03BA03
ATC
hydroxocobalamin; parenteral
7.2
8.2
19
28
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
5.9
8.2
22
40
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
10.5
8.1
15
15
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.7
8.1
35
104
R03AC03
ATC
terbutaline; inhalant
2.8
8.1
54
220
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
34.5
8.1
10
*
R03AK11
ATC
formoterol and fluticasone; inhalant
7.7
8.1
18
25
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.7
8.1
35
105
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
5.8
8.0
22
41
R03AK07
ATC
formoterol and budesonide; inhalant
2.5
8.0
70
331
R01BA52
ATC
pseudoephedrine, combinations; oral
2.2
8.0
98
552
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.8
8.0
34
100
N02BE01
ATC
paracetamol; systemic, rectal
2.7
8.0
223
1816
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
3.4
7.9
39
130
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.2
7.9
43
152
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.5
7.8
37
119
R1250
NOMESCO Finland
Evaluation of functional capability
7.8
7.8
17
23
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
15.6
7.8
12
8
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.4
7.8
77
390
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
7.7
71
347
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
19.1
7.7
11
6
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
19.1
7.7
11
6
UDM02
NOMESCO Finland
Sinoscopy
9.3
7.7
15
17
212
Kela drug reimbursment
Gout
25.9
7.6
10
*
J96.0
ICD-10 Finland
Acute respiratory failure
25.9
7.6
10
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
25.9
7.6
10
*
J01DA08
ATC
[U] cefaclor; oral
2.9
7.6
47
182
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
7.5
7.6
17
24
A06AD11
ATC
lactulose; oral
3.4
7.6
37
122
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.2
7.6
39
134
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
82.4
7.5
8
*
JN4AD
NOMESCO Finland
Body CT examination
4.1
7.5
28
74
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.6
7.4
18
29
27510
ICD-8 Finland
Plasma protein abnormalities, Hypogammaglobulinaemia
+∞
7.3
7
*
2790C
ICD-9 Finland
Disorders involving the immune mechanism, Deficiency of humoral immunity[DEFICIENTIA IMMUNOGLOBULINI ALIA]
+∞
7.3
7
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
7.3
30
86
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.6
7.3
32
97
J01CA04
ATC
amoxicillin; systemic
2.6
7.3
224
1857
RD210
NOMESCO Finland
NA
8.3
7.2
15
19
5BA08
NOMESCO Finland
NA
31.0
7.2
9
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
20.7
7.2
10
5
J15.8
ICD-10 Finland
Other bacterial pneumonia
20.7
7.2
10
5
D07AB08
ATC
desonide; topical
3.0
7.2
41
151
K29.3
ICD-10 Finland
Chronic superficial gastritis
9.2
7.1
14
16
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
7.1
84
461
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
6.7
7.1
17
27
R06AE09
ATC
levocetirizine; oral
2.6
7.0
55
245
WX892
NOMESCO Finland
Monitored bed care
3.6
7.0
31
95
A28
ICPC
Limited function/disability NOS
3.4
6.9
33
107
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
11.4
6.9
12
11
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
9.7
6.9
13
14
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
9.7
6.9
13
14
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
9.7
6.9
13
14
L04AA06
ATC
mycophenolic acid; systemic
9.7
6.9
13
14
A04AA01
ATC
ondansetron; systemic, rectal
3.9
6.8
27
75
R81
ICPC
Pneumonia
7.5
6.8
15
21
N06AX21
ATC
duloxetine; oral
2.9
6.8
42
162
N03AX11
ATC
topiramate; oral
5.8
6.7
18
33
J05AH02
ATC
oseltamivir; oral
23.2
6.7
9
*
A87.9
ICD-10 Finland
Viral meningitis, unspecified
23.2
6.7
9
*
B99
ICPC
Blood/lymph/spleen disease other
23.2
6.7
9
*
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
8.2
6.7
14
18
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.2
6.7
80
441
1XC02
NOMESCO Finland
NA
12.7
6.6
11
9
N05BA01
ATC
diazepam; systemic, rectal
2.7
6.6
45
186
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.5
6.6
16
26
Z50.1
ICD-10 Finland
Other physical therapy
4.7
6.5
21
48
XF404
NOMESCO Finland
Ambulatory ECG
3.6
6.5
28
84
Z71.8
ICD-10 Finland
Other specified counselling
2.2
6.5
73
389
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
71.5
6.5
7
*
J32.8
ICD-10 Finland
Other chronic sinusitis
71.5
6.5
7
*
D73.1
ICD-10 Finland
Hypersplenism
71.5
6.5
7
*
R51.80
ICD-10 Finland
Headache
2.6
6.4
49
214
127
Kela drug reimbursment
Transplant complication
8.5
6.4
13
16
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.3
6.3
14
20
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
18.6
6.3
9
5
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
18.6
6.3
9
5
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.6
6.3
17
32
D84.1
ICD-10 Finland
Defects in the complement system
+∞
6.3
6
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
+∞
6.3
6
*
3XA02
NOMESCO Finland
NA
+∞
6.3
6
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
6.3
6
*
D81.1
ICD-10 Finland
Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
+∞
6.3
6
*
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
6.3
6
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
27.4
6.3
8
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.2
6.3
32
110
A07EA06
ATC
budesonide; oral, local oral
4.9
6.2
19
41
N03AX12
ATC
gabapentin; oral
2.6
6.2
46
199
R03AK08
ATC
formoterol and beclometasone; inhalant
4.6
6.2
20
46
J01DC02
ATC
cefuroxime; systemic
3.6
6.2
27
82
L04AX01
ATC
azathioprine; systemic
4.4
6.2
21
51
PJA10
NOMESCO Finland
Exploration of lymph nodes
12.9
6.1
10
8
D70.89
ICD-10 Finland
Neutropenic splenomegaly
12.9
6.1
10
8
TQW99
NOMESCO Finland
Other minor procedure on skin
5.4
6.1
17
33
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.0
6.1
35
129
A02BC05
ATC
esomeprazole; systemic
2.0
6.1
109
701
SAA04
NOMESCO Finland
Special inverstigation of mouth
3.8
6.1
24
67
N03AX09
ATC
lamotrigine; oral
4.1
6.1
22
57
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
235
157
65.47
302.47
5.5
1.6
1.0
1.6
g/l
1.17
203
149
137
11
228.38
283.06
3.4
1.4
—
—
—
0
0
104
19
83.25
190.67
3.6
1.3
523.7
824.9
e6/l
0.75
87
13
102
19
80.82
186.18
3.6
1.3
0.2
0.2
e9/l
0.02
87
13
71
22
41.97
113.37
3.0
1.5
800.4
770.7
e6/l
0.06
18
11
140
178
13.87
113.28
2.1
1.2
80.8
258.2
u/ml
0.71
94
164
238
589
15.71
113.16
5.7
1.4
1.2
2.3
g/l
13.40
165
376
78
46
22.56
97.99
6.3
5.3
676.7
213.6
iu/ml
—
13
7
74
55
17.53
82.27
3.6
2.8
—
—
—
0
0
69
55
15.99
73.46
2.8
1.8
—
—
—
0
0
83
89
12.51
73.41
3.4
1.5
—
—
—
0
0
69
56
15.70
72.68
2.9
1.8
—
—
—
0
0
67
53
15.99
71.57
1.8
1.2
—
—
—
0
0
99
145
9.70
69.07
3.1
1.6
—
—
—
0
0
48
20
28.38
68.70
3.5
1.1
—
—
—
0
0
48
21
27.02
67.45
3.5
1.1
—
—
—
0
0
80
94
11.24
65.98
2.0
1.4
1.2
1.2
g/l
0.49
73
89
133
310
6.91
59.59
3.9
1.9
—
—
—
0
0
266
1202
11.70
57.52
25.3
5.9
57.9
56.2
%
1.43
266
1136
267
1215
11.89
57.19
26.8
6.0
28.3
29.5
%
1.01
267
1146
108
213
7.36
56.92
3.3
1.7
—
—
—
0
0
53
41
15.49
56.89
2.3
1.6
—
—
—
0
0
41
21
22.46
53.79
5.2
2.4
—
—
—
0
0
103
216
6.74
50.54
3.7
1.7
—
—
—
0
0
38
20
21.61
49.16
5.4
2.5
—
—
—
0
0
48
40
14.10
49.13
2.9
2.0
—
—
—
0
0
35
20
19.68
43.52
1.8
1.9
—
—
—
0
0
39
0
+∞
41.64
2.1
0.0
1.0
—
mg/l
—
27
0
39
0
+∞
41.64
2.1
0.0
0.7
—
mg/l
—
24
0
39
0
+∞
41.64
2.1
0.0
0.9
—
mg/l
—
27
0
39
0
+∞
41.64
2.1
0.0
0.7
—
mg/l
—
25
0
39
0
+∞
41.64
2.1
0.0
1.2
—
mg/l
—
23
0
39
0
+∞
41.64
2.1
0.0
0.4
—
mg/l
—
25
0
39
0
+∞
41.64
2.1
0.0
1.1
—
mg/l
—
24
0
39
0
+∞
41.64
2.1
0.0
1.9
—
mg/l
—
22
0
39
0
+∞
41.64
2.1
0.0
3.2
—
mg/l
—
25
0
39
0
+∞
41.64
2.1
0.0
2.9
—
mg/l
—
24
0
108
280
5.46
41.27
3.2
2.5
21.6
23.9
%
0.69
96
240
39
33
13.43
39.32
2.8
1.6
—
—
—
0
0
31
17
20.22
39.17
1.1
7.7
—
42.2
u/ml
—
0
6
42
41
11.75
38.66
2.2
1.5
—
—
—
0
0
38
32
13.45
38.40
2.2
1.8
—
—
—
0
0
46
52
10.27
38.21
3.5
1.4
—
—
—
0
0
34
25
15.21
37.11
2.6
1.7
—
—
—
0
0
41
41
11.42
37.09
1.7
2.1
119.3
132.4
g/l
—
8
29
38
35
12.29
36.27
2.5
1.6
—
—
—
0
0
285
1807
12.54
31.70
23.8
7.3
90.0
77.8
u/l
5.18
285
1705
40
48
9.46
31.61
2.0
1.5
—
—
—
0
0
285
1822
12.28
30.97
16.8
3.9
12.2
9.7
mm/h
2.64
280
1692
38
44
9.74
30.83
9.0
3.8
55.4
56.8
%
0.19
38
44
208
1060
4.14
29.79
16.3
7.1
1.2
1.2
mmol/l
0.21
181
904
31
29
11.81
29.13
2.9
1.7
—
—
—
0
0
84
232
4.64
28.74
3.2
1.9
327.1
364.3
nmol/l
0.94
77
216
30
30
11.00
26.93
4.6
1.5
—
—
—
0
0
191
964
3.70
26.72
18.0
6.4
1.2
1.2
mmol/l
2.14
183
882
29
28
11.36
26.64
1.4
1.3
—
—
—
0
0
25
19
14.26
26.57
2.4
2.2
—
—
—
0
0
25
19
14.26
26.57
2.4
2.2
—
—
—
0
0
25
19
14.26
26.57
2.4
2.2
—
—
—
0
0
30
31
10.64
26.32
4.6
1.5
—
—
—
0
0
30
31
10.64
26.32
4.6
1.5
—
—
—
0
0
30
31
10.64
26.32
4.6
1.5
—
—
—
0
0
30
31
10.64
26.32
4.6
1.5
—
—
—
0
0
30
31
10.64
26.32
4.6
1.5
—
—
—
0
0
29
5
63.89
25.49
1.1
1.0
—
—
—
0
0
43
72
6.80
25.44
2.0
2.5
1.3
1.4
g/l
0.29
33
63
24
19
13.64
24.88
4.6
3.2
—
—
—
0
0
28
5
61.46
24.48
1.1
1.0
96.2
83.2
%
—
28
5
20
12
17.79
23.94
2.5
2.3
—
—
—
0
0
20
12
17.79
23.94
2.5
2.3
—
—
—
0
0
20
12
17.79
23.94
2.5
2.3
—
—
—
0
0
20
12
17.79
23.94
2.5
2.3
—
—
—
0
0
37
58
7.14
23.22
1.5
1.3
2.5
0.9
u/ml
—
8
5
160
770
3.31
23.21
6.2
3.1
—
—
—
0
0
21
15
14.98
23.00
4.1
1.4
24.2
30.2
umol/l
1.01
21
15
48
100
5.52
22.64
1.6
1.3
0.5
3.9
u/ml
—
8
7
30
39
8.44
22.08
1.7
1.3
—
—
—
0
0
30
39
8.44
22.08
1.7
1.3
—
—
—
0
0
18
11
17.34
21.28
3.2
1.4
—
—
—
0
0
39
71
6.16
21.16
3.4
2.5
2.9
3.1
g/l
0.55
26
62
40
75
6.00
21.06
3.4
2.4
7.1
7.4
g/l
0.36
27
64
40
75
6.00
21.06
3.4
2.4
—
—
—
0
0
40
75
6.00
21.06
3.4
2.4
2.8
3.7
g/l
3.34
26
61
48
107
5.15
20.94
2.3
1.4
—
—
—
0
0
22
20
11.79
20.89
1.5
1.2
245.5
89.1
u/l
0.36
17
13
22
20
11.79
20.89
1.6
1.1
0.4
0.1
u/ml
—
13
7
36
64
6.26
19.97
1.4
1.5
382.0
270.2
ug/g
2.62
30
41
20
17
12.53
19.77
1.1
1.1
—
—
—
0
0
18
13
14.67
19.51
1.8
1.2
—
—
—
0
0
25
9
30.13
19.05
1.5
1.4
—
—
—
0
0
42
91
5.20
18.86
2.2
2.4
—
—
—
0
0
129
603
3.00
18.76
5.3
2.9
0.3
0.4
e6/l
0.31
111
444
33
58
6.27
18.48
1.6
1.3
25.1
49.1
u/ml
—
10
6
30
48
6.83
18.38
2.3
1.9
—
—
—
0
0
26
36
7.81
18.09
1.5
1.4
—
—
—
0
0
30
51
6.42
17.34
1.7
1.3
91.3
108.4
u/ml
—
12
8
61
191
3.75
16.99
14.2
4.5
1.8
2.2
mmol/l
0.40
55
145
209
1311
2.96
16.88
13.8
4.8
6.4
6.5
mmol/l
0.26
203
1215
22
27
8.71
16.85
1.6
1.1
—
—
—
0
0
36
76
5.25
16.60
1.6
1.3
1.4
6.4
u/ml
—
7
19
129
636
2.80
16.57
4.8
2.0
124.8
255.9
u/l
0.69
123
609
82
317
3.18
16.35
4.1
2.2
30.2
29.7
s
0.33
75
310
16
13
12.94
16.15
1.1
1.2
—
—
—
0
0
22
29
8.11
15.90
1.6
1.1
—
—
—
0
0
35
76
5.08
15.61
1.6
1.3
3.5
3.2
u/ml
—
5
12
18
19
10.01
15.37
3.2
1.6
—
—
—
0
0
20
8
26.63
14.89
1.5
1.1
—
—
—
0
0
20
8
26.63
14.89
1.5
1.1
—
—
—
0
0
82
333
3.01
14.88
1.9
1.6
1390.6
1137.0
nmol/l
1.45
71
249
113
545
2.72
14.85
2.9
1.8
1.0
0.9
mg/l
0.22
98
401
17
18
9.95
14.46
1.1
1.7
—
—
—
0
0
102
479
2.71
14.00
5.2
2.7
1066.7
657.2
ng/l
0.41
92
379
17
19
9.42
13.90
2.2
1.2
—
—
—
0
0
18
22
8.64
13.77
1.3
1.1
—
—
—
0
0
100
477
2.64
13.19
2.2
1.4
22.1
22.4
nmol/l
0.07
94
410
14
13
11.25
12.95
3.4
1.8
—
—
—
0
0
31
72
4.69
12.74
3.6
2.4
7.3
10.6
g/l
2.88
26
66
293
2526
7.85
12.63
53.0
11.5
15.9
20.0
mg/l
2.93
288
1908
16
19
8.84
12.48
2.2
1.2
—
—
—
0
0
43
130
3.69
12.46
5.5
2.4
207.4
113.5
ng/l
0.39
38
115
14
14
10.44
12.32
3.4
1.7
—
—
—
0
0
31
74
4.56
12.31
6.5
1.9
—
—
—
0
0
182
1175
2.40
12.08
5.6
3.2
0.0
0.0
estimate
0.00
48
225
17
23
7.78
11.96
1.5
1.1
—
—
—
0
0
182
1179
2.38
11.92
6.9
4.4
0.0
0.0
estimate
0.50
50
228
31
76
4.43
11.91
1.5
1.1
—
—
—
0
0
17
9
19.93
11.72
2.8
2.8
—
—
—
0
0
17
9
19.93
11.72
2.8
2.8
—
—
—
0
0
17
9
19.93
11.72
2.8
2.8
—
—
—
0
0
53
191
3.16
11.64
22.0
11.0
5.0
5.1
kpa
0.30
47
181
53
191
3.16
11.64
22.0
11.0
11.1
12.6
kpa
1.20
46
182
291
2519
6.17
11.50
48.2
12.5
139.4
139.7
mmol/l
1.27
291
2457
27
61
4.77
11.45
1.6
1.3
—
—
—
0
0
182
1192
2.34
11.44
5.6
3.2
0.0
0.0
estimate
0.50
50
219
67
281
2.78
11.20
5.2
2.7
8.4
6.4
umol/l
0.31
60
249
16
22
7.63
11.09
1.2
1.1
—
—
—
0
0
52
192
3.07
10.93
22.4
11.1
0.9
1.4
mmol/l
0.35
38
149
291
2531
5.99
10.93
48.4
12.6
3.9
3.9
mmol/l
1.43
291
2461
53
198
3.04
10.92
5.1
3.1
—
—
—
0
0
88
428
2.49
10.88
2.0
1.6
496.0
18206965.4
pmol/l
0.50
82
368
13
14
9.66
10.84
3.6
1.7
—
—
—
0
0
13
14
9.66
10.84
1.7
1.5
—
—
—
0
0
136
807
2.25
10.60
2.6
1.8
89.3
97.7
pmol/l
1.41
89
406
130
759
2.26
10.52
5.3
3.1
2.3
2.4
mmol/l
3.55
124
658
28
70
4.31
10.48
1.6
1.4
0.0
0.0
iu/ml
—
6
13
15
8
19.65
10.37
1.2
2.3
—
—
iu/ml
—
0
0
14
18
8.11
10.22
3.3
1.7
4.3
4.8
mg/l
0.10
14
18
82
399
2.45
10.04
5.9
3.1
216.2
276.5
ng/l
0.20
55
261
12
13
9.57
9.93
1.8
1.5
1.2
3.7
u/l
—
6
7
11
11
10.34
9.60
1.9
2.4
—
—
—
0
0
11
11
10.34
9.60
1.9
2.4
—
—
—
0
0
22
50
4.67
9.24
5.5
4.7
23.1
29.9
mg/l
0.28
16
42
22
50
4.67
9.24
5.5
4.7
19.5
159.8
mg/l
0.63
15
43
105
589
2.20
9.12
5.6
2.8
320.5
4878.0
umol/l
1.95
99
515
34
108
3.42
9.10
2.6
1.8
—
—
—
0
0
13
7
19.33
9.01
1.3
1.1
—
—
—
0
0
14
21
6.94
8.97
3.6
1.3
32.1
32.7
pg
0.17
14
21
39
138
3.10
8.77
8.1
3.4
0.7
1.7
mmol/l
0.67
29
94
108
622
2.15
8.71
6.9
3.4
0.0
0.0
estimate
0.80
50
225
12
6
20.75
8.54
1.8
1.5
—
—
—
0
0
10
11
9.37
8.13
1.1
1.1
—
—
—
0
0
39
147
2.90
7.84
8.2
3.3
4.9
5.1
kpa
1.45
34
136
31
102
3.27
7.84
15.7
11.7
25.5
24.9
mmol/l
0.43
26
94
15
28
5.59
7.81
1.8
1.3
—
—
—
0
0
267
2223
2.83
7.79
54.2
14.3
14.2
13.5
%
10.34
267
2195
26
77
3.60
7.72
1.9
1.2
—
—
—
0
0
26
77
3.60
7.72
4.3
2.2
—
—
—
0
0
140
927
1.96
7.43
5.9
3.2
—
—
—
0
0
39
153
2.78
7.28
2.8
3.5
4.2
4.6
pmol/l
2.29
34
135
13
23
5.86
7.13
1.0
1.1
—
—
—
0
0
11
8
14.21
6.94
3.2
2.0
83.6
60.1
ug/l
—
11
8
11
17
6.68
6.82
1.4
1.0
—
—
—
0
0
66
345
2.17
6.61
3.8
2.7
3.7
2.8
e6/l
0.38
37
177
154
1081
1.87
6.60
7.3
3.9
—
—
—
0
0
67
355
2.14
6.47
3.4
2.6
1.1
0.8
e6/l
0.27
37
186
10
7
14.72
6.44
1.1
1.0
—
—
—
0
0
12
22
5.64
6.34
1.1
1.1
—
—
—
0
0
10
8
12.87
6.12
1.1
1.1
1530.6
1868.5
miu/ml
—
10
8
13
27
4.99
6.03
2.8
1.8
90.2
90.9
%
0.20
13
27
79
459
1.98
5.91
1.4
1.3
29.6
34.0
iu/ml
0.16
22
154
14
32
4.54
5.83
3.0
1.9
1.6
1.7
mmol/l
0.31
14
32
12
24
5.17
5.79
1.2
1.2
—
—
—
0
0
77
450
1.96
5.64
1.4
1.3
2.3
9.0
u/ml
2.08
30
186
12
25
4.96
5.54
1.2
1.2
—
—
—
0
0
47
232
2.22
5.38
2.9
2.4
32.1
27.1
u/l
0.38
42
195
5
0
+∞
5.22
1.4
0.0
—
—
—
0
0
9
9
10.26
5.06
1.7
1.2
—
—
—
0
0
112
764
1.74
4.90
5.6
3.1
113.7
29.9
ng/l
0.44
71
426
85
540
1.80
4.72
4.0
2.3
—
—
—
0
0
22
81
2.85
4.62
6.5
4.1
60.6
53.0
%
0.63
22
81
10
21
4.89
4.56
1.3
1.3
—
—
—
0
0
10
21
4.89
4.56
1.3
1.3
—
—
—
0
0
264
2324
2.13
4.49
35.2
10.7
91.0
88.4
ml/min/173m2
1.14
250
1891
10
22
4.67
4.33
1.3
1.3
—
—
—
0
0
10
22
4.67
4.33
1.3
1.3
—
—
—
0
0
10
22
4.67
4.33
1.3
1.3
—
—
—
0
0
13
36
3.73
4.25
4.5
2.7
15.4
16.8
%
—
8
16
7
7
10.20
4.03
1.7
1.0
—
—
—
0
0
8
11
7.44
3.88
1.8
1.5
—
—
—
0
0
8
11
7.44
3.88
1.8
1.5
—
—
—
0
0
7
8
8.92
3.79
1.3
1.5
—
—
—
0
0
8
12
6.81
3.69
2.8
4.8
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
9
7.93
3.57
1.4
1.2
—
—
—
0
0
228
1962
1.68
3.57
5.1
3.9
14.8
14.5
pmol/l
1.25
219
1819
290
2704
3.17
3.52
31.9
9.4
30.9
27.3
u/l
2.53
290
2625
9
19
4.85
3.26
1.2
1.5
2.4
5.7
u/field
—
9
7
34
180
2.00
3.26
2.6
2.4
62.8
71.4
ml/min/173m2
0.47
16
75
14
49
2.95
3.23
1.3
1.1
—
—
—
0
0
213
1826
1.57
3.14
5.5
3.0
52.3
43.0
u/l
1.80
208
1740
88
623
1.58
3.12
1.8
1.6
—
—
—
0
0
8
16
5.10
3.07
3.3
3.4
94.5
100.7
%
—
8
16
8
16
5.10
3.07
4.6
2.3
—
—
—
0
0
6
8
7.62
3.07
1.0
1.0
—
—
—
0
0
5
5
10.14
2.99
1.2
1.0
—
—
—
0
0
5
5
10.14
2.99
2.2
1.0
—
—
—
0
0
257
2323
1.74
2.89
5.9
4.6
1.9
1.8
mu/l
0.49
252
2173
10
31
3.30
2.80
1.2
1.2
—
—
—
0
0
12
291
0.39
2.79
1.5
1.7
—
—
—
0
0
9
23
4.00
2.79
1.4
1.2
—
—
—
0
0
222
1956
1.52
2.57
4.7
3.4
—
—
—
0
0
13
50
2.67
2.56
2.4
1.1
88.3
5.5
iu/ml
—
7
10
6
11
5.54
2.55
2.5
1.2
4.2
5.9
umol/l
—
6
11
6
13
4.69
2.28
1.2
1.9
8.4
10.0
umol/l
—
6
13
23
122
1.96
2.23
1.1
1.4
336.6
253.9
miu/ml
0.44
12
61
8
24
3.40
2.19
1.0
1.0
—
—
—
0
0
30
175
1.79
2.19
1.7
1.3
—
34.5
—
0
10
12
49
2.51
2.13
1.1
1.2
1.4
1.6
u/ml
—
5
14
16
76
2.17
2.06
1.8
1.1
—
—
—
0
0
10
38
2.69
2.03
1.5
1.3
304.8
13.4
u/l
—
10
33
16
77
2.14
2.00
1.8
1.1
—
—
—
0
0
20
106
1.95
1.96
1.5
1.3
—
—
—
0
0
8
27
3.01
1.95
1.3
2.9
7.9
3.0
nmol/l
—
8
27
5
11
4.60
1.95
1.0
1.5
—
—
—
0
0
5
11
4.60
1.95
1.0
1.5
—
—
—
0
0
13
59
2.26
1.87
1.5
1.2
—
—
—
0
0
6
17
3.58
1.84
3.2
3.3
—
—
—
0
0
10
42
2.43
1.69
1.9
1.9
8.3
9.0
umol/l
—
10
29
18
98
1.89
1.65
1.8
1.4
—
—
—
0
0
49
353
1.46
1.57
3.0
2.8
2.5
2.4
mmol/l
0.60
42
301
32
211
1.58
1.54
1.9
1.2
80.3
148.9
iu/ml
0.75
15
83
5
15
3.37
1.53
2.2
1.4
—
—
—
0
0
29
188
1.60
1.49
2.7
2.0
—
—
—
0
0
81
645
1.35
1.47
1.4
1.4
0.6
1.7
u/ml
2.37
15
175
11
52
2.16
1.46
1.1
1.2
2.4
3.5
u/ml
—
5
24
6
22
2.76
1.44
1.2
1.7
—
—
—
0
0
15
260
0.55
1.43
16.2
5.6
—
—
—
0
0
9
41
2.23
1.38
1.6
1.3
—
—
—
0
0
5
19
2.66
1.22
1.0
1.9
1.0
1.0
g/l
—
5
19
237
2496
0.76
1.10
4.0
4.1
4.6
4.8
mmol/l
1.54
228
2350
15
91
1.68
1.02
1.4
1.7
—
—
—
0
0
294
2884
1.97
0.96
65.5
17.1
131.8
137.1
g/l
7.75
294
2848
228
2398
0.79
0.90
3.7
3.6
1.4
1.3
mmol/l
1.72
221
2237
48
387
1.29
0.81
2.6
2.0
—
—
—
0
0
0
26
0.00
0.79
0.0
1.1
—
—
—
0
0
73
623
1.23
0.77
4.1
4.0
23.5
11.0
mg/mmol
0.33
47
381
22
159
1.41
0.75
2.0
2.5
49.0
50.1
u/ml
0.02
22
152
243
2525
0.80
0.74
4.3
4.4
2.8
2.9
mmol/l
1.23
232
2361
239
2487
0.81
0.74
3.8
4.0
1.4
1.5
mmol/l
1.83
229
2328
17
120
1.44
0.66
4.8
2.8
0.3
0.1
e6/l
0.75
17
115
50
420
1.23
0.62
2.7
2.1
—
—
—
0
0
8
52
1.55
0.60
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.4
—
—
—
0
0
30
239
1.28
0.58
2.9
2.1
—
—
—
0
0
20
156
1.30
0.46
1.6
1.3
—
—
—
0
0
10
136
0.73
0.38
2.7
1.4
—
—
—
0
0
5
76
0.65
0.36
1.6
1.6
—
—
—
0
0
43
385
1.14
0.29
1.7
2.0
1.7
1.4
%
0.80
37
353
5
71
0.70
0.26
1.2
1.4
—
—
—
0
0
5
71
0.70
0.26
1.2
1.4
—
—
—
0
0
5
71
0.70
0.26
1.2
1.4
—
—
—
0
0
235
2399
0.91
0.26
4.7
4.0
5.7
5.8
mmol/l
0.23
229
2227
250
2453
1.11
0.26
48.1
12.2
39.7
40.7
%
2.81
202
1956
52
477
1.11
0.24
1.6
1.5
—
—
—
0
0
36
324
1.13
0.23
2.8
2.6
0.7
0.7
ug/l
0.03
28
181
5
39
1.29
0.23
2.2
1.8
13.8
13.2
%
—
5
39
46
423
1.10
0.21
3.1
3.8
19.8
22.9
%
0.58
20
157
6
52
1.16
0.19
2.5
1.8
—
—
—
0
0
5
66
0.75
0.17
1.2
1.1
0.6
1.4
u/ml
—
5
24
8
69
1.16
0.16
1.3
1.8
213.4
243.0
pmol/l
—
8
62
71
674
1.07
0.16
1.5
1.7
1.3
1.4
mmol/l
0.51
66
582
13
151
0.85
0.16
1.1
1.0
—
—
—
0
0
6
57
1.05
0.08
3.0
1.7
0.7
0.8
nmol/l
—
6
48
221
2232
0.96
0.08
5.6
5.0
37.8
38.7
mmol/mol
0.67
215
2110
12
122
0.98
0.00
1.5
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
66.5
—
0
5
5
56
0.89
0.00
1.8
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
67
0.89
0.00
1.8
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_KELA_IMMUDEF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_KELA_IMMUDEF | 5.013 [3.21, 7.83] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.595 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 416 females with D3_KELA_IMMUDEF died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have D3_KELA_IMMUDEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.44% | No data |
| 5 | 3.202% | No data |
| 10 | 7.618% | No data |
| 15 | 14.22% | No data |
| 20 | 23.763% | No data |
Relationships between endpoints
↥Index endpoint: D3_KELA_IMMUDEF – Kela reimbursement Agammaglobulinemia (D80-84)
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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