No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditions
|
519188 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
283 |
4. Check minimum number of eventsNone |
283 |
5. Include endpointsNone |
283 |
6. Filter based on genotype QC (FinnGen only) |
270 |
Control definitions (FinnGen only)
- Control conditions
- not Q17_CLEFT_PALATE_EXCLUDE
Extra metadata
- First used in FinnGen datafreeze
- DF10
Similar endpoints
↥List of similar endpoints to
Cleft lip and cleft lip and palate
based on the number of shared cases.
Similar with more cases:
- Cleft lip, lip and palate or palate
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3787 | 1514 | 2265 |
| Only index persons | 3203 | 1302 | 1901 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.04 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 0.78 | 1.04 | 0.51 |
| Only index persons | 1.26 | 2.28 | 0.56 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 270 | 144 | 126 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.06 |
| Median age at first event (years) | 7.37 | 11.60 | 2.53 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 281
- Matched controls
- 2809
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
+∞
169.4
145
*
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
+∞
106.1
95
*
4361
FHL
Lip plastic or reconstruction due to cleft lip
+∞
73.2
67
*
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
+∞
73.2
67
*
EAB30
NOMESCO Finland
Correction of cleft lip
+∞
66.3
61
*
SBB10
NOMESCO Finland
Dental impressions
9.1
64.8
100
160
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
+∞
64.0
59
*
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
14.1
60.7
61
54
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
13.2
58.9
62
59
SAA04
NOMESCO Finland
Special examination of mouth
9.3
49.4
68
93
Q35.1
ICD-10 Finland
Cleft hard palate
543.4
47.8
46
*
Q36.9
ICD-10 Finland
Cleft lip, unilateral
+∞
47.2
44
*
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
10.7
46.5
56
64
ECB17
NOMESCO Finland
Operation of gingival cleft
+∞
46.1
43
*
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
15.9
44.2
40
29
EB1MA
NOMESCO Finland
Cephalometry with X-ray
11.8
43.7
48
48
74924
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis bilateralis
+∞
42.8
40
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
7.7
42.3
69
114
4367
FHL
Bone transfer to the upper jaw
+∞
41.7
39
*
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
15.1
39.9
37
28
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
10.5
37.9
45
50
4368
FHL
Closing the fistula of the mouth
+∞
37.3
35
*
7492C
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS BILATERALIS COMPLETA]
+∞
37.3
35
*
4122
FHL
Tympanostomy (tympanic tube)
14.1
36.4
35
28
4365
FHL
Correction of nasal deformity
+∞
36.2
34
*
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
11.1
32.8
37
38
EEC05
NOMESCO Finland
Le Fort I osteotomy
186.1
32.4
33
*
ZSZ10
NOMESCO Finland
Secondary repair operation
186.1
32.4
33
*
EBB10
NOMESCO Finland
Insertion of dental implant
44.9
32.1
39
10
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
37.4
30.9
39
12
4364
FHL
Pharyngeal tongue plastic
+∞
30.8
29
*
74910
ICD-8 Finland
Cleft palate and cleft lip, Cheiloschisis unilateralis
+∞
30.8
29
*
DLW00
NOMESCO Finland
Correction of cleft nose
+∞
27.5
26
*
4362
FHL
Nozzle reconstruction
+∞
26.5
25
*
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
7.8
25.7
38
55
K00.00
ICD-10 Finland
Hypodontia
27.4
25.0
34
14
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
8.8
24.8
33
42
ZXD10
NOMESCO Finland
Scheduled procedure
3.5
23.6
143
644
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
8.2
23.4
33
45
74929
ICD-8 Finland
Cleft palate and cleft lip, Unspecified
+∞
23.2
22
*
Q35.9
ICD-10 Finland
Cleft palate, unspecified
+∞
22.2
21
*
Q37.99
ICD-10 Finland
Cleft palate with cleft lip NOS
+∞
22.2
21
*
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
8.1
21.2
30
41
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
+∞
21.1
20
*
4366
FHL
Upper jaw scar repair surgery
+∞
21.1
20
*
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
7.6
20.8
31
45
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
9.1
20.5
26
31
74912
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathoschisis unilateralis
+∞
20.0
19
*
EHC10
NOMESCO Finland
Plastic repair of oronasal or oroantral fistula of palate
+∞
20.0
19
*
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
79.0
20.0
22
*
EBB15
NOMESCO Finland
Insertion of dental implant abutment
49.9
19.5
23
5
DLD20
NOMESCO Finland
Rhinoplasty
59.4
19.2
22
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.7
19.0
32
53
Z2221
NOMESCO Finland
Medical doctor
3.1
18.3
114
507
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
39.5
17.9
22
6
UDC00
NOMESCO Finland
Ear microscopy
5.0
17.2
40
90
ZZG00
NOMESCO Finland
Graft of cartilage
+∞
16.8
16
*
K07.14
ICD-10 Finland
Retrognaty, maxillary
95.8
16.8
18
*
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
14.8
16.4
27
20
Q37.90
ICD-10 Finland
Unspecified cheft palate with cleft lip, unilateral
+∞
15.8
15
*
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
+∞
15.8
15
*
9808
FHL
Bone graft
169.0
15.6
16
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.7
15.1
133
696
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
19.7
14.9
22
12
4204
FHL
Molding of the cartilaginous part of the nose
157.8
14.6
15
*
SPC20
NOMESCO Finland
Implant borne crown
45.0
14.3
17
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
5.2
14.1
31
66
SJC10
NOMESCO Finland
Orthodontic band in one tooth
6.0
14.1
26
47
7491B
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOSCHISIS UNILATERALIS INCOMPLETA]
+∞
13.6
13
*
ZSZ00
NOMESCO Finland
Primary repair operation
+∞
13.6
13
*
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
146.7
13.6
14
*
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
146.7
13.6
14
*
SXC05
NOMESCO Finland
Other oral or dental procedure
3.7
13.1
46
141
ZXB10
NOMESCO Finland
Medial
30.0
13.1
17
6
ZXE10
NOMESCO Finland
More than one and less than three hours
2.6
13.0
117
609
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
52.6
13.0
15
*
SAA03
NOMESCO Finland
Extended examination of mouth
2.5
12.8
156
935
DLD10
NOMESCO Finland
Reconstruction of cartilage and bone of nose
+∞
12.6
12
*
4347
FHL
Osteotomy of the upper jaw
135.8
12.5
13
*
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
48.9
12.0
14
*
Q37.3
ICD-10 Finland
Cleft soft palate with unilateral cleft lip
+∞
11.5
11
*
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
10.7
11.2
21
21
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
62.4
10.7
12
*
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
5.3
10.7
22
44
SPF20
NOMESCO Finland
Temporary relining of dentures
114.1
10.5
11
*
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
+∞
10.5
10
*
7491A
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOSCHISIS UNILATERALIS COMPLETA]
+∞
10.5
10
*
7491F
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOGNATOSCHISIS UNILATERALIS INCOMPLETA]
+∞
10.5
10
*
EHC40
NOMESCO Finland
Repair of submucous cleft palate
+∞
10.5
10
*
1450
FHL
Otomicroscopy
33.9
10.4
13
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.4
10.1
26
63
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
9.3
10.0
20
23
SPF10
NOMESCO Finland
Demanding reparation of dental prosthesis
27.1
9.9
13
5
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
9.9
88
447
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.8
9.8
31
88
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
9.8
143
894
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
57.0
9.7
11
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.0
9.5
47
177
4203
FHL
Mobilization and repositioning of the external pyramid
103.3
9.5
10
*
Q36.0
ICD-10 Finland
Cleft lip, bilateral
+∞
9.4
9
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
9.4
9
*
Q35.71
ICD-10 Finland
Submucous cleft palate
+∞
9.4
9
*
ZXE00
NOMESCO Finland
One hour or less
2.2
9.3
122
726
EBA10
NOMESCO Finland
Operative extraction of tooth
2.5
9.0
65
298
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
10.0
8.9
17
18
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
4.5
8.8
22
52
DLD00
NOMESCO Finland
Reconstruction of cartilage of nose
51.6
8.7
10
*
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
16.9
8.6
13
8
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
13.3
8.5
14
11
ECB60
NOMESCO Finland
Reconstruction of alveolus
+∞
8.4
8
*
Q37.8
ICD-10 Finland
Unspecified cleft palate with bilateral cleft lip
+∞
8.4
8
*
SXC03
NOMESCO Finland
Other oral or dental procedure
15.1
8.3
13
9
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
7.6
8.1
18
25
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
22.8
8.1
11
5
ZZH22
NOMESCO Finland
Graft of patients own bone, block
46.3
7.8
9
*
SPE90
NOMESCO Finland
Other partial denture
19.0
7.7
11
6
SPB20
NOMESCO Finland
Temporary bridge
25.8
7.6
10
*
J34.2
ICD-10 Finland
Deviated nasal septum
3.4
7.6
28
88
J01DA08
ATC
[U] cefaclor
2.5
7.4
53
241
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
9.8
7.4
14
15
ENC80
NOMESCO Finland
Plastic operation of soft palate for voice distubance
+∞
7.3
7
*
74913
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathoschisis bilateralis
+∞
7.3
7
*
SPF30
NOMESCO Finland
Relining of denture
16.3
7.3
11
7
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.6
7.3
46
197
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
4.2
7.0
19
48
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
6.4
6.9
17
28
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
12.7
6.6
11
9
EB1WA, ,
NOMESCO Finland
12.7
6.6
11
9
R1260
NOMESCO Finland
Evaluation of communicative skills
10.4
6.6
12
12
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
5.6
6.6
18
34
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
5.6
6.6
18
34
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
7.7
6.5
14
19
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.4
6.5
46
208
EAB20
NOMESCO Finland
Plastic repair of lip
71.4
6.5
7
*
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
71.4
6.5
7
*
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
4.2
6.4
17
42
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.7
6.3
20
57
Q37.2
ICD-10 Finland
Cleft soft palate with bilateral cleft lip
+∞
6.3
6
*
Q67.48
ICD-10 Finland
Other specified congenital deformity of skull, face or jaw
+∞
6.3
6
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
6.3
6
*
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
27.3
6.3
8
*
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
27.3
6.3
8
*
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
3.1
6.2
27
94
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
10
28
3.66
2.81
1.2
1.3
—
—
—
0
0
46
311
1.57
1.97
2.2
2.5
1.28
0.74
e6/l
0.61
27
169
19
102
1.92
1.81
15.6
11.5
95.57
94.75
%
0.73
19
102
19
104
1.89
1.72
15.6
11.3
1.41
1.43
%
0.02
19
104
19
105
1.87
1.67
15.5
11.2
0.78
0.75
%
0.13
19
105
215
2305
0.71
1.56
10.8
10.7
23.76
20.72
mg/l
0.54
156
1729
5
16
3.16
1.44
1.4
1.3
91.20
76.94
umol/l
—
5
16
31
209
1.54
1.37
11.9
7.6
105.06
104.70
mmol/l
0.25
31
209
0
37
0.00
1.35
0.0
1.6
—
—
—
0
0
9
42
2.18
1.35
3.8
6.0
—
3429.38
—
0
8
44
321
1.44
1.34
4.4
3.2
114.80
351.51
ng/l
0.98
30
210
0
41
0.00
1.32
0.0
1.5
—
—
—
0
0
25
368
0.65
1.26
1.4
1.3
1.34
6.98
u/ml
2.47
12
140
0
35
0.00
1.16
0.0
5.4
—
694.73
—
0
35
26
178
1.51
1.10
12.1
11.6
5.13
5.16
kpa
0.06
26
168
26
178
1.51
1.10
12.1
11.6
13.24
13.02
kpa
0.07
26
169
23
157
1.51
0.99
19.1
9.7
1.10
1.33
mmol/l
0.72
23
151
0
30
0.00
0.98
0.0
1.7
—
—
—
0
0
39
297
1.36
0.96
2.2
2.7
1.66
3.08
e6/l
0.83
21
155
51
405
1.32
0.95
1.2
1.4
—
—
—
0
0
23
159
1.49
0.94
1.0
1.0
—
—
—
0
0
9
52
1.75
0.93
3.4
5.1
—
688.00
—
0
6
14
87
1.64
0.89
11.1
5.8
121.93
130.97
g/l
0.57
14
87
6
32
1.89
0.82
1.8
1.6
—
—
—
0
0
0
24
0.00
0.79
0.0
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
1.8
—
—
—
0
0
0
24
0.00
0.79
0.0
1.8
—
—
—
0
0
8
48
1.69
0.79
1.1
1.1
—
—
—
0
0
5
100
0.49
0.79
1.0
1.5
—
—
—
0
0
0
26
0.00
0.79
0.0
1.3
—
—
—
0
0
0
26
0.00
0.79
0.0
1.8
—
—
—
0
0
11
173
0.62
0.78
2.3
2.3
—
20.07
—
0
11
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
79
680
1.22
0.77
3.0
2.9
—
—
—
0
0
21
150
1.43
0.76
13.2
11.3
121.43
128.16
g/l
0.70
21
144
8
134
0.59
0.75
4.3
1.9
—
—
—
0
0
7
40
1.77
0.72
1.0
1.2
—
—
—
0
0
5
26
1.94
0.71
1.2
1.6
—
—
—
0
0
30
381
0.76
0.69
1.3
1.3
28.81
26.35
iu/ml
—
9
127
57
480
1.23
0.69
2.3
2.2
—
—
—
0
0
10
155
0.63
0.68
1.2
1.3
—
23.11
—
0
7
258
2638
0.73
0.68
15.7
15.9
261.26
255.87
e9/l
0.66
250
2572
121
1323
0.85
0.66
7.5
9.8
3.93
3.90
e9/l
0.03
100
1138
258
2637
0.73
0.66
16.6
16.0
40.70
41.15
%
0.59
246
2515
238
2456
0.80
0.65
9.2
8.8
27.79
28.59
u/l
0.24
233
2390
182
1924
0.85
0.65
5.0
4.5
38.38
38.38
mmol/mol
0.00
177
1833
11
71
1.57
0.63
13.4
5.7
0.64
0.68
%
0.18
11
71
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
259
2641
0.75
0.57
15.7
15.9
4.65
4.62
e12/l
0.56
251
2571
11
74
1.51
0.54
13.4
5.5
1.53
1.31
%
0.21
11
74
151
1607
0.87
0.54
7.4
6.8
80.10
80.66
u/l
0.06
146
1510
30
244
1.26
0.50
1.6
2.1
—
—
—
0
0
14
101
1.41
0.50
1.6
2.5
0.30
0.10
e6/l
0.63
14
96
12
166
0.71
0.49
1.2
1.5
—
—
—
0
0
13
93
1.42
0.49
2.0
1.8
—
—
—
0
0
73
653
1.16
0.47
2.0
1.7
89.24
97.22
pmol/l
0.87
39
330
18
139
1.31
0.45
17.6
10.8
26.00
25.33
mmol/l
0.36
18
139
24
293
0.80
0.43
1.9
1.7
—
—
—
0
0
57
640
0.86
0.42
2.5
2.9
22.50
25.41
ng/l
0.10
31
353
8
58
1.39
0.42
1.9
1.8
0.37
0.86
nmol/l
—
8
49
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
2.56
—
0
17
151
1589
0.89
0.40
3.9
3.7
8.92
8.91
mm/h
0.01
143
1486
52
459
1.16
0.40
1.8
2.3
2.70
2.77
mg/l
0.07
45
393
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
10
136
0.73
0.38
4.4
3.3
4.09
4.87
pmol/l
—
10
122
59
529
1.15
0.37
3.0
2.7
0.16
0.31
e6/l
0.92
45
393
5
37
1.36
0.37
3.6
1.7
13.70
13.19
%
—
5
37
9
71
1.28
0.36
2.8
4.2
25.66
24.60
mmol/l
—
9
71
5
79
0.63
0.36
15.8
11.1
1.34
1.21
mg/l
—
5
74
34
391
0.85
0.35
5.5
3.2
1493.90
725.33
ng/l
0.37
29
314
68
743
0.89
0.34
13.8
8.7
1.22
1.14
inr
0.32
20
228
6
87
0.68
0.33
1.0
1.5
—
—
—
0
0
6
87
0.68
0.33
1.0
1.5
—
—
—
0
0
6
87
0.68
0.33
1.0
1.5
—
—
—
0
0
11
143
0.76
0.33
1.5
1.3
—
—
—
0
0
67
614
1.12
0.31
1.8
1.6
—
—
—
0
0
7
53
1.33
0.31
2.3
1.3
—
—
—
0
0
7
53
1.33
0.31
1.3
1.8
—
—
—
0
0
110
1036
1.10
0.31
3.5
3.0
0.00
0.00
estimate
-0.00
18
202
15
120
1.26
0.30
1.5
1.4
297.39
254.85
miu/ml
—
10
60
51
460
1.13
0.30
1.8
2.2
0.87
1.17
mg/l
0.58
43
347
83
771
1.11
0.30
4.3
3.2
28.37
31.48
u/l
0.60
78
735
10
76
1.33
0.28
1.2
1.5
—
—
—
0
0
109
1030
1.09
0.28
5.2
4.3
0.00
0.00
estimate
-0.00
18
201
28
243
1.17
0.28
1.5
1.5
735.44
1211.56
nmol/l
2.74
22
193
211
2057
1.10
0.26
3.8
3.6
5.81
5.72
mmol/l
0.37
203
1921
10
127
0.78
0.26
1.1
1.6
—
—
—
0
0
9
74
1.22
0.25
1.0
1.5
—
—
—
0
0
175
1695
1.09
0.24
4.1
3.7
14.32
14.53
pmol/l
0.62
167
1578
108
1134
0.92
0.24
5.5
6.3
29.04
29.82
%
0.32
101
1080
21
180
1.18
0.24
3.3
4.5
227.62
244.45
u/l
0.40
21
173
6
81
0.73
0.24
1.7
1.1
—
—
—
0
0
11
88
1.26
0.23
1.8
1.7
—
—
—
0
0
40
364
1.11
0.22
3.6
3.6
16.71
20.99
%
0.73
12
134
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.3
—
72.40
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
96.00
—
0
6
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
109.67
—
0
6
0
13
0.00
0.21
0.0
1.1
—
1640.54
—
0
13
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
13
0.00
0.21
0.0
1.0
—
122.31
—
0
13
0
13
0.00
0.21
0.0
9.5
—
34.83
—
0
6
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
4.29
—
0
7
109
1046
1.07
0.18
3.5
3.0
0.00
0.02
estimate
0.50
17
190
65
613
1.08
0.18
2.1
3.0
2.38
2.36
mmol/l
0.72
55
559
77
809
0.93
0.17
3.5
3.0
—
—
—
0
0
5
67
0.74
0.17
1.4
2.2
—
—
—
0
0
13
111
1.18
0.16
2.5
2.6
64.26
67.12
g/l
0.90
13
105
216
2193
0.93
0.16
3.6
3.7
1.42
1.45
mmol/l
0.62
207
2079
6
76
0.78
0.16
1.8
1.3
—
—
—
0
0
6
80
0.74
0.15
1.2
2.2
—
—
—
0
0
53
499
1.08
0.15
2.2
2.2
—
—
—
0
0
8
96
0.83
0.14
1.9
1.6
—
—
—
0
0
99
956
1.05
0.13
2.5
2.5
—
—
—
0
0
30
277
1.09
0.13
3.0
2.4
0.60
0.68
ug/l
0.38
17
143
51
537
0.94
0.12
3.5
3.2
0.00
0.01
estimate
0.50
18
197
78
808
0.95
0.11
5.6
5.0
37.10
37.14
g/l
0.02
73
765
110
1129
0.96
0.11
5.3
6.1
56.40
55.51
%
0.35
104
1073
64
615
1.05
0.10
1.2
1.4
1.08
1.85
u/ml
0.98
20
147
32
300
1.07
0.10
2.0
2.4
2.43
2.43
mmol/l
0.04
27
261
49
468
1.06
0.10
3.6
3.7
7.17
11.31
mg/mmol
0.48
38
306
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
11
97
1.14
0.09
2.7
12.2
25.55
24.18
mmol/l
1.13
11
91
7
64
1.10
0.08
1.4
1.5
—
—
—
0
0
19
205
0.92
0.08
4.3
5.9
—
—
—
0
0
226
2239
1.05
0.08
12.6
11.5
3.94
3.94
mmol/l
0.05
220
2181
7
81
0.86
0.07
1.3
1.4
—
—
—
0
0
21
197
1.07
0.06
1.6
2.0
—
—
—
0
0
204
2056
0.97
0.05
10.0
9.2
89.78
92.07
ml/min/173m2
0.72
160
1665
45
464
0.96
0.05
4.3
3.4
1.51
2.42
ug/l
0.67
45
420
204
2025
1.03
0.04
4.7
4.3
1.90
1.83
mu/l
0.42
199
1905
195
1935
1.02
0.04
3.7
3.5
—
—
—
0
0
91
896
1.02
0.04
9.2
7.7
1.21
1.22
mmol/l
0.36
85
783
219
2201
0.98
0.03
3.6
3.8
4.78
4.78
mmol/l
0.00
211
2096
16
153
1.05
0.01
2.0
2.7
—
—
—
0
0
19
196
0.97
0.00
1.1
1.3
207.12
168.89
iu/ml
—
10
81
45
444
1.02
0.00
2.0
2.1
—
—
—
0
0
10
105
0.95
0.00
1.6
1.4
—
—
—
0
0
26
264
0.98
0.00
1.8
1.8
—
—
—
0
0
222
2224
0.99
0.00
4.0
4.0
2.96
2.91
mmol/l
0.37
213
2101
10
102
0.98
0.00
1.6
1.3
—
—
—
0
0
210
2104
0.99
0.00
3.2
3.4
1.32
1.29
mmol/l
0.24
200
1986
19
187
1.02
0.00
1.9
1.7
—
—
—
0
0
19
186
1.02
0.00
1.8
1.7
—
—
—
0
0
119
1187
1.00
0.00
6.2
5.0
6.85
6.36
mmol/l
1.02
111
1087
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
27.87
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
98
0.92
-0.00
1.9
2.2
29.56
39.67
u/l
—
9
90
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
2.6
3.9
3.74
3.92
mmol/l
—
5
51
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
8
79
1.01
-0.00
1.1
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
58
0.86
-0.00
1.4
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
129.50
—
0
8
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
8.27
—
0
7
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
12.30
—
0
5
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
43.40
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CLEFT_LIP_OR_LIP_AND_PALATE and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have Q17_CLEFT_LIP_OR_LIP_AND_PALATE.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: Q17_CLEFT_LIP_OR_LIP_AND_PALATE – Cleft lip and cleft lip and palate
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data