No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditions
|
519447 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
283 |
4. Check minimum number of eventsNone |
283 |
5. Include endpointsNone |
283 |
6. Filter based on genotype QC (FinnGen only) |
283 |
Control definitions (FinnGen only)
- Control conditions
- not Q17_CLEFT_PALATE_EXCLUDE
Extra metadata
- First used in FinnGen datafreeze
- DF10
Similar endpoints
↥List of similar endpoints to
Cleft lip and cleft lip and palate
based on the number of shared cases.
Similar with more cases:
- Cleft lip, lip and palate or palate
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3787 | 1514 | 2265 |
| Only index persons | 3203 | 1302 | 1901 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.04 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 0.78 | 1.04 | 0.51 |
| Only index persons | 1.26 | 2.28 | 0.56 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 283 | 152 | 131 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.06 |
| Median age at first event (years) | 7.44 | 12.14 | 1.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 256
- Matched controls
- 2571
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q37.1
ICD-10 Finland
Cleft hard palate with unilateral cleft lip
+∞
147.5
127
*
74920
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis unilateralis
+∞
98.4
88
*
7492A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS UNILATERALIS COMPLETA]
+∞
66.6
61
*
4361
FHL
Lip plastic or reconstruction due to cleft lip
+∞
64.3
59
*
Q37.0
ICD-10 Finland
Cleft hard palate with bilateral cleft lip
+∞
58.6
54
*
EAB30
NOMESCO Finland
Correction of cleft lip
+∞
55.2
51
*
74924
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathopalatoschisis bilateralis
+∞
40.7
38
*
Q36.9
ICD-10 Finland
Cleft lip, unilateral
+∞
40.7
38
*
Q35.1
ICD-10 Finland
Cleft hard palate
100.1
39.1
42
5
4367
FHL
Bone transfer to the upper jaw
+∞
37.4
35
*
ECB17
NOMESCO Finland
Operation for cleft gingiva
+∞
37.4
35
*
SBB10
NOMESCO Finland
Teeth copy
8.9
36.8
87
140
7492C
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate with cleft lip[CHEILOPALATOSCHISIS BILATERALIS COMPLETA]
+∞
35.2
33
*
4368
FHL
Closing the fistula of the mouth
+∞
33.0
31
*
4365
FHL
Correction of nasal deformity
+∞
31.9
30
*
74910
ICD-8 Finland
Cleft palate and cleft lip, Cheiloschisis unilateralis
+∞
30.9
29
*
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
11.1
28.3
56
63
ZSZ10
NOMESCO Finland
Secondary repair operation
313.9
28.3
28
*
4364
FHL
Pharyngeal tongue plastic
300.8
27.3
27
*
SAA04
NOMESCO Finland
Special inverstigation of mouth
8.6
25.7
59
86
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
27.8
25.1
34
14
EBB10
NOMESCO Finland
Insertion of dental implant
27.8
25.1
34
14
EEC05
NOMESCO Finland
Le Fort I osteotomy
54.2
24.9
29
6
DLW00
NOMESCO Finland
Correction of cleft nose
+∞
24.4
23
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
9.5
24.3
52
67
K00.00
ICD-10 Finland
Hypodontia
31.8
23.8
31
11
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
8.9
23.5
52
71
74929
ICD-8 Finland
Cleft palate and cleft lip, Unspecified
+∞
23.3
22
*
4362
FHL
Nozzle reconstruction
131.8
23.0
24
*
4366
FHL
Upper jaw scar repair surgery
+∞
21.1
20
*
DLD20
NOMESCO Finland
Rhinoplasty
+∞
21.1
20
*
Q35.9
ICD-10 Finland
Cleft palate, unspecified
+∞
21.1
20
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
6.7
20.6
56
103
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
14.3
20.1
34
27
74912
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathoschisis unilateralis
+∞
20.1
19
*
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
9.3
18.0
38
47
Q37.99
ICD-10 Finland
Cleft palate with cleft lip NOS
+∞
17.9
17
*
74900
ICD-8 Finland
Cleft palate and cleft lip, Cleft palate
102.2
17.8
19
*
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
102.2
17.8
19
*
EHC10
NOMESCO Finland
Plastic repair of oronasal or oroantral fistula of palate
192.7
17.7
18
*
4122
FHL
Tympanostomy (tympanic tube)
12.0
17.5
32
30
EB1MA
NOMESCO Finland
Cephalometry with X-ray
7.5
17.0
41
63
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
10.1
16.5
33
37
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
34.0
15.0
19
6
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
9.4
15.0
31
37
ZZG00
NOMESCO Finland
Graft of cartilage
+∞
14.7
14
*
4204
FHL
Molding of the cartilaginous part of the nose
+∞
14.7
14
*
K07.14
ICD-10 Finland
Retrognaty, maxillary
38.5
14.6
18
5
9808
FHL
Bone graft
+∞
13.7
13
*
4347
FHL
Osteotomy of the upper jaw
+∞
13.7
13
*
EBB15
NOMESCO Finland
Insertion of dental implant abutment
19.6
13.6
20
11
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
11.9
13.3
24
22
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
10.1
12.8
25
27
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
73.6
12.7
14
*
7491B
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOSCHISIS UNILATERALIS INCOMPLETA]
+∞
12.6
12
*
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
6.6
12.1
31
52
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
8.4
12.0
26
34
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.6
11.6
116
615
ZSZ00
NOMESCO Finland
Primary repair operation
125.4
11.5
12
*
38401
ICD-8 Finland
Other inflammatory diseases of ear, Rhinosalpingitis (otosalpingitis) chronica adhaesiva
29.5
10.8
14
5
SPA20
NOMESCO Finland
Selection and insertion of implantdistans
62.7
10.7
12
*
SAA03
NOMESCO Finland
Extended examination of mouth
2.4
10.7
138
829
SJB60
NOMESCO Finland
External device grinding and adaptation
8.8
10.6
22
27
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
17.0
10.5
16
10
7491A
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOSCHISIS UNILATERALIS COMPLETA]
+∞
10.5
10
*
4203
FHL
Mobilization and repositioning of the external pyramid
+∞
10.5
10
*
7490A
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS COMPLETA]
34.1
10.4
13
*
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
6.2
10.1
27
48
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
15.4
10.1
16
11
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.6
10.0
25
41
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
5.9
9.5
26
48
SJC00
NOMESCO Finland
Bracket with fixed attachment
31.3
9.5
12
*
ZXB10
NOMESCO Finland
Medial
31.3
9.5
12
*
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
31.3
9.5
12
*
Q37.90
ICD-10 Finland
Unspecified cheft palate with cleft lip, unilateral
+∞
9.4
9
*
Q37.3
ICD-10 Finland
Cleft soft palate with unilateral cleft lip
+∞
9.4
9
*
DLD10
NOMESCO Finland
Reconstruction of cartilage and bone of nose
51.8
8.7
10
*
EBA10
NOMESCO Finland
Surgical removal of tooth
2.8
8.7
59
244
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
28.6
8.6
11
*
SPB10
NOMESCO Finland
Production of temporary crone to tooth
28.6
8.6
11
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
93.0
8.5
9
*
7490B
ICD-9 Finland
Cleft palate and cleft lip, Cleft palate[PALATOSCHISIS INCOMPLETA]
93.0
8.5
9
*
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
9.0
8.4
17
20
DLD00
NOMESCO Finland
Reconstruction of cartilage of nose
+∞
8.4
8
*
Q36.0
ICD-10 Finland
Cleft lip, bilateral
+∞
8.4
8
*
ECB60
NOMESCO Finland
Reconstruction of alveolus
+∞
8.4
8
*
EHC40
NOMESCO Finland
Correction of submucous cleft palate
+∞
8.4
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
8.3
82
417
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
5.6
8.2
23
44
SPC40
NOMESCO Finland
Preparation of first or second intermediate attachment tooth for bridge
34.5
8.1
10
*
SPB20
NOMESCO Finland
Temporary bridge between two or more teeth
34.5
8.1
10
*
SXC05
NOMESCO Finland
Other oral or dental procedure
3.5
8.1
38
121
SPF30
NOMESCO Finland
Soling for prothesis
22.9
8.1
11
5
R4130
NOMESCO Finland
Speech therapy
13.6
8.0
13
10
1450
FHL
Otomicroscopy
15.6
7.8
12
8
SPF10
NOMESCO Finland
Demanding repatation of teeth prosthesis
15.6
7.8
12
8
Q35.71
ICD-10 Finland
Submucous cleft palate
46.4
7.8
9
*
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
19.1
7.7
11
6
SXC03
NOMESCO Finland
Other oral or dental procedure
12.4
7.7
13
11
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
4.2
7.6
28
73
Q37.8
ICD-10 Finland
Unspecified cleft palate with bilateral cleft lip
+∞
7.3
7
*
7491F
ICD-9 Finland
Cleft palate and cleft lip, Cleft lip[CHEILOGNATOSCHISIS UNILATERALIS INCOMPLETA]
+∞
7.3
7
*
74913
ICD-8 Finland
Cleft palate and cleft lip, Cheilognathoschisis bilateralis
+∞
7.3
7
*
UDC00
NOMESCO Finland
Ear microscopy
3.8
7.2
30
87
SPF20
NOMESCO Finland
Temporary soling for filling
20.7
7.2
10
5
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
5.5
7.1
20
39
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
7.9
7.0
15
20
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
6.4
6.9
17
28
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
6.7
122
795
4305
FHL
Tooth extraction by cutting
23.2
6.7
9
*
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
12.7
6.6
11
9
J34.2
ICD-10 Finland
Deviated nasal septum
4.0
6.6
25
67
ZZH22
NOMESCO Finland
Graft of patients own bone, block
18.6
6.3
9
5
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
5.6
6.3
17
32
EAB20
NOMESCO Finland
Plastic repair of lip
+∞
6.3
6
*
M95.0
ICD-10 Finland
Acquired deformity of nose
27.4
6.3
8
*
H66.9
ICD-10 Finland
Otitis media, unspecified
3.1
6.2
32
111
EBA00
NOMESCO Finland
Extraction of tooth
2.0
6.1
99
613
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.9
6.1
38
147
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
10
28
3.66
3.22
1.2
1.3
—
—
—
0
0
7
17
4.19
2.37
1.3
1.3
60.3
101.9
u/l
—
7
10
46
311
1.57
1.97
2.2
2.5
1.3
0.7
e6/l
0.61
27
169
19
102
1.92
1.81
15.6
11.5
95.6
94.7
%
0.73
19
102
19
104
1.89
1.72
15.6
11.3
1.4
1.4
%
0.02
19
104
19
105
1.87
1.67
15.5
11.2
0.8
0.8
%
0.13
19
105
215
2306
0.71
1.58
10.8
10.7
23.8
20.7
mg/l
0.54
156
1730
0
37
0.00
1.35
0.0
1.6
—
—
—
0
0
9
42
2.18
1.35
3.8
6.0
—
3429.4
—
0
8
31
210
1.53
1.34
11.9
7.6
105.1
104.6
mmol/l
0.29
31
204
44
322
1.43
1.32
4.4
3.2
114.8
351.6
ng/l
0.98
30
210
0
41
0.00
1.32
0.0
1.5
—
—
—
0
0
15
84
1.83
1.29
19.3
12.6
25.5
24.3
mmol/l
0.68
15
77
25
368
0.65
1.26
1.4
1.3
1.3
7.0
u/ml
2.47
12
140
0
35
0.00
1.16
0.0
5.4
—
694.7
—
0
35
26
178
1.51
1.10
12.1
11.6
5.1
5.2
kpa
0.06
26
168
26
178
1.51
1.10
12.1
11.6
13.2
13.0
kpa
0.07
26
169
23
157
1.51
0.99
19.1
9.7
1.1
1.3
mmol/l
0.68
23
148
0
30
0.00
0.98
0.0
1.7
—
—
—
0
0
39
297
1.36
0.96
2.2
2.7
1.7
3.1
e6/l
0.83
21
155
51
405
1.32
0.95
1.2
1.4
—
—
—
0
0
9
52
1.75
0.93
3.4
5.1
—
688.0
—
0
6
23
160
1.48
0.92
1.0
1.0
—
—
—
0
0
14
87
1.64
0.89
11.1
5.8
121.9
131.0
g/l
0.57
14
87
6
32
1.89
0.82
1.8
1.6
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
0
24
0.00
0.79
0.0
1.7
—
—
—
0
0
8
48
1.69
0.79
1.1
1.1
—
—
—
0
0
5
100
0.49
0.79
1.0
1.5
—
—
—
0
0
0
26
0.00
0.79
0.0
1.8
—
—
—
0
0
0
26
0.00
0.79
0.0
1.3
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
1.7
—
—
—
0
0
79
681
1.22
0.76
3.0
2.9
—
—
—
0
0
21
150
1.43
0.76
13.2
11.3
121.4
128.1
g/l
0.68
21
142
8
134
0.59
0.75
4.3
1.9
—
—
—
0
0
7
40
1.77
0.72
1.0
1.2
—
—
—
0
0
5
26
1.94
0.71
1.2
1.6
—
—
—
0
0
30
381
0.76
0.69
1.3
1.3
28.8
26.5
iu/ml
—
9
126
57
481
1.23
0.68
2.3
2.2
—
—
—
0
0
121
1324
0.85
0.67
7.5
9.8
3.9
3.9
e9/l
0.03
100
1139
238
2457
0.79
0.66
9.2
8.8
27.8
28.6
u/l
0.24
233
2391
182
1925
0.84
0.66
5.1
4.5
38.4
38.4
mmol/mol
0.00
177
1834
0
21
0.00
0.60
0.0
1.6
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
219
2271
0.84
0.56
13.9
11.8
40.5
41.0
%
0.59
183
1904
151
1608
0.87
0.55
7.4
6.8
80.2
80.7
u/l
0.05
145
1510
11
74
1.51
0.54
13.4
5.5
1.5
1.3
%
0.21
11
74
12
167
0.71
0.51
1.2
1.5
—
—
—
0
0
30
244
1.26
0.50
1.7
2.1
—
—
—
0
0
13
93
1.42
0.49
2.0
1.8
—
—
—
0
0
14
102
1.39
0.48
1.6
2.5
0.3
0.1
e6/l
0.63
14
97
73
654
1.16
0.46
2.0
1.7
89.2
97.3
pmol/l
0.88
39
331
18
139
1.31
0.45
17.6
10.8
26.0
25.3
mmol/l
0.36
18
139
57
641
0.86
0.43
2.5
2.9
22.5
25.5
ng/l
0.11
31
352
24
293
0.80
0.43
1.9
1.7
—
—
—
0
0
8
58
1.39
0.42
1.9
1.8
0.4
0.9
nmol/l
—
8
49
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
0
15
0.00
0.41
0.0
3.6
—
—
—
0
0
151
1590
0.89
0.41
3.9
3.7
8.9
8.9
mm/h
0.01
143
1487
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
52
460
1.16
0.39
1.8
2.3
2.7
2.8
mg/l
0.07
45
394
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
10
136
0.73
0.38
4.4
3.3
4.1
4.9
pmol/l
—
10
122
5
37
1.36
0.37
3.6
1.7
13.7
13.2
%
—
5
37
59
530
1.14
0.36
3.0
2.7
0.2
0.3
e6/l
0.92
45
391
34
391
0.85
0.35
5.5
3.2
1493.9
725.3
ng/l
0.37
29
314
6
87
0.68
0.33
1.0
1.5
—
—
—
0
0
6
87
0.68
0.33
1.0
1.5
—
—
—
0
0
6
87
0.68
0.33
1.0
1.5
—
—
—
0
0
11
143
0.76
0.33
1.5
1.3
—
—
—
0
0
110
1035
1.10
0.31
3.5
3.0
0.0
0.0
estimate
0.00
18
192
7
53
1.33
0.31
2.3
1.3
—
—
—
0
0
7
53
1.33
0.31
1.3
1.8
—
—
—
0
0
15
120
1.26
0.30
1.5
1.4
297.4
254.8
miu/ml
—
10
60
51
460
1.13
0.30
1.8
2.2
0.9
1.2
mg/l
0.58
43
347
67
615
1.12
0.30
1.8
1.6
—
—
—
0
0
83
772
1.11
0.30
4.3
3.2
28.4
31.5
u/l
0.60
78
736
10
76
1.33
0.28
1.2
1.5
—
—
—
0
0
109
1030
1.09
0.28
5.2
4.3
0.0
0.0
estimate
0.00
18
201
28
244
1.16
0.27
1.5
1.5
735.4
1211.2
nmol/l
2.74
22
194
10
127
0.78
0.26
1.1
1.6
—
—
—
0
0
211
2058
1.10
0.26
3.8
3.6
5.8
5.7
mmol/l
0.37
203
1922
9
73
1.24
0.25
1.0
1.5
—
—
—
0
0
6
81
0.73
0.24
1.7
1.1
—
—
—
0
0
175
1696
1.08
0.24
4.1
3.7
14.3
14.5
pmol/l
0.61
167
1579
21
181
1.17
0.23
3.3
4.5
227.6
244.5
u/l
0.40
21
173
11
88
1.26
0.23
1.8
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
4.3
—
72.4
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
40
365
1.11
0.21
3.6
3.6
16.7
21.0
%
0.73
12
134
0
13
0.00
0.21
0.0
1.0
—
109.7
—
0
6
0
13
0.00
0.21
0.0
9.5
—
34.8
—
0
6
0
13
0.00
0.21
0.0
1.1
—
1640.5
—
0
13
0
13
0.00
0.21
0.0
1.0
—
96.0
—
0
6
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
13
0.00
0.21
0.0
1.0
—
122.3
—
0
13
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
4.3
—
0
7
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
6
49
1.23
0.20
1.3
1.8
9.2
10.4
g/l
—
6
44
109
1046
1.07
0.18
3.5
3.0
0.0
0.0
estimate
0.50
17
190
14
119
1.19
0.18
16.9
7.4
23.9
23.9
mmol/l
0.03
14
114
77
809
0.93
0.17
3.5
3.0
—
—
—
0
0
65
614
1.08
0.17
2.1
3.0
2.4
2.4
mmol/l
0.72
54
558
5
68
0.73
0.17
1.4
2.1
—
—
—
0
0
216
2194
0.93
0.16
3.6
3.7
1.4
1.5
mmol/l
0.62
207
2076
13
111
1.18
0.16
2.5
2.6
64.3
67.1
g/l
0.90
13
105
6
76
0.78
0.16
1.8
1.3
—
—
—
0
0
6
80
0.74
0.15
1.2
2.3
—
—
—
0
0
53
499
1.08
0.15
2.2
2.2
—
—
—
0
0
8
96
0.83
0.14
1.9
1.6
—
—
—
0
0
30
277
1.09
0.13
3.0
2.4
0.6
0.7
ug/l
0.38
17
143
99
957
1.05
0.13
3.8
3.9
—
—
—
0
0
51
537
0.94
0.12
3.5
3.2
0.0
0.0
estimate
0.50
18
197
78
809
0.95
0.12
5.6
5.0
37.1
37.1
g/l
0.02
73
764
32
299
1.08
0.11
2.0
2.4
2.4
2.4
mmol/l
0.04
27
260
5
48
1.04
0.09
1.0
1.1
—
—
—
0
0
11
97
1.14
0.09
2.7
12.2
25.5
24.2
mmol/l
1.12
11
91
7
64
1.10
0.08
1.4
1.5
—
—
—
0
0
19
205
0.92
0.08
4.3
5.9
—
—
—
0
0
226
2240
1.04
0.07
12.6
11.5
3.9
3.9
mmol/l
0.02
220
2181
7
81
0.86
0.07
1.3
1.4
—
—
—
0
0
21
197
1.07
0.06
1.6
2.0
—
—
—
0
0
45
465
0.96
0.05
4.3
3.4
1.5
2.4
ug/l
0.67
45
421
83
813
1.03
0.05
10.2
7.3
1.2
1.2
mmol/l
0.74
78
754
63
615
1.03
0.05
1.2
1.4
1.1
1.8
u/ml
1.00
19
147
204
2024
1.03
0.05
4.7
4.3
1.9
1.8
mu/l
0.42
199
1904
195
1934
1.03
0.04
3.7
3.5
—
—
—
0
0
219
2202
0.97
0.04
3.6
3.8
4.8
4.8
mmol/l
0.01
211
2093
91
896
1.02
0.04
9.2
7.7
1.2
1.2
mmol/l
0.29
85
780
204
2050
0.98
0.02
9.9
9.2
89.9
92.0
ml/min/173m2
0.66
160
1655
16
153
1.05
0.01
2.0
2.7
—
—
—
0
0
19
196
0.97
0.00
1.1
1.3
207.1
168.9
iu/ml
—
10
81
45
444
1.02
0.00
2.0
2.1
—
—
—
0
0
222
2225
0.99
0.00
4.0
4.0
3.0
2.9
mmol/l
0.37
213
2098
210
2105
0.99
0.00
3.2
3.4
1.3
1.3
mmol/l
0.23
200
1987
10
105
0.95
0.00
1.6
1.4
—
—
—
0
0
26
265
0.98
0.00
1.8
1.8
—
—
—
0
0
10
102
0.98
0.00
1.6
1.3
—
—
—
0
0
19
187
1.02
0.00
1.9
1.7
—
—
—
0
0
17
166
1.03
0.00
26.6
16.4
1.0
1.2
inr
—
5
32
19
186
1.02
0.00
1.8
1.7
—
—
—
0
0
119
1188
1.00
0.00
6.2
5.0
6.9
6.4
mmol/l
1.01
111
1086
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
27.9
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
5
58
0.86
0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
12.3
—
0
5
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
129.5
—
0
8
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
8.3
—
0
7
9
98
0.92
0.00
1.9
2.2
29.6
39.7
u/l
—
9
90
0
7
0.00
0.00
0.0
5.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
8
79
1.01
0.00
1.1
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_CLEFT_LIP_OR_LIP_AND_PALATE and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have Q17_CLEFT_LIP_OR_LIP_AND_PALATE.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: Q17_CLEFT_LIP_OR_LIP_AND_PALATE – Cleft lip and cleft lip and palate
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data