This is a non-core endpoint: only basic statistics are computed.

Nail disorders in diseases classified elsewhere

L12_NAILINOTH

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L62* Cause of death: ICD-10 — L62* 2 out of 7 registries used, show all original rules.	13
4. Check minimum number of events None	13
5. Include endpoints None	13
6. Filter based on genotype QC (FinnGen only)	13

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2

NAME	L12_NAILINOTH
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L62
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L62
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Nail disorders in diseases classified elsewhere based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	87	57	29
Only index persons	78	54	24
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	47.24	51.94	38.74
Only index persons	48.31	50.76	42.80

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	13	11	-
Unadjusted period prevalence (%)	0.00	0.00	-
Median age at first event (years)	49.96	48.30	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3023368) Bacteria identified in Blood by Culture

6.00

2.50

2.6

3.1

—

(42870588) Differential panel, method unspecified - Blood

2.96

1.07

5.3

4.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

2.74

0.86

3.2

2.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

2.48

0.81

3.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.00

0.66

0.0

5.5

—

(1761868) Lipid panel - Serum or Plasma

1.83

0.48

3.6

3.1

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.83

0.48

5.4

6.6

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

1.67

0.42

12.8

7.3

1.2

mmol/l

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

1.69

0.29

9.0

2.2

2.3

2.4

mmol/l

—

(3003694) ABO and Rh group [Type] in Blood

1.69

0.29

1.2

1.3

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

1.40

0.26

9.4

5.9

1.2

mmol/l

—

(40768804) Tissue Pathology biopsy report

1.41

0.25

1.7

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

1.40

0.24

15.1

7.7

9.1

9.8

umol/l

—

(4035726)

0.00

0.22

0.0

1.1

—

(40761535) Cells panel - Urine sediment

0.00

0.22

0.0

4.7

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.3

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.0

1.3

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.0

1.3

—

(4034850)

0.00

0.0

8.2

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3019060) Gas panel - Arterial blood

0.00

0.0

5.5

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.0

1.3

—

(40768443) Skin Pathology biopsy report

0.00

0.0

1.3

—

(40768793) Breast Pathology biopsy report

0.00

0.0

1.0

—

(3049717) Cytology report of Urine Cyto stain

0.00

0.0

2.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.0

1.6

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.6

—

(3031040) Bacteria [#/volume] in Urine by Automated count

0.94

0.00

3.9

4.2

—

(3008898) HLA-B27 [Presence]

0.00

0.0

1.0

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

1.07

0.00

3.7

3.0

—

(4010399)

0.00

0.0

1.3

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.10

0.00

2.0

3.4

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

0.00

0.0

5.0

—

1.0

—

(3014007) Fractional oxyhemoglobin in Arterial blood

0.00

0.0

5.0

—

94.4

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

4.4

—

12.7

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

0.94

0.00

5.7

4.9

—

(3044889) 12 lead EKG panel

0.91

0.00

2.6

3.3

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

0.0

2.3

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

0.00

0.0

5.0

—

1.7

—

(3020891) Body temperature

0.00

0.0

3.4

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.1

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_NAILINOTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_NAILINOTH.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_NAILINOTH – Nail disorders in diseases classified elsewhere

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Nail disorders in diseases classified elsewhere

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints