labyrinthitis: Inflammation of the inner ear. The cause is often not clear. It may be due to a virus, but it can also arise from bacterial infection, head injury, extreme stress, an allergy, or as a reaction to medication. [ https://en.wikipedia.org/wiki/Labyrinthitis NCIT:C128369 ]
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
123 |
4. Check minimum number of eventsNone |
123 |
5. Include endpointsNone |
123 |
6. Filter based on genotype QC (FinnGen only) |
115 |
Control definitions (FinnGen only)
- Control exclude
- H8_INNER
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H83
- Name in latin
- Labyrinthitis
Similar endpoints
↥List of similar endpoints to
Labyrinthitis
based on the number of shared cases.
Similar with more cases:
- Diseases of inner ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1255 | 675 | 574 |
| Only index persons | 913 | 513 | 400 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 36.37 | 39.34 | 32.62 |
| Only index persons | 37.48 | 39.64 | 34.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 115 | 80 | 35 |
| Unadjusted period prevalence (%) | 0.02 | 0.03 | 0.02 |
| Median age at first event (years) | 44.24 | 39.34 | 55.44 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 123
- Matched controls
- 1230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H83.0
ICD-10 Finland
Labyrinthitis
+∞
100.1
82
*
38403
ICD-8 Finland
Other inflammatory diseases of ear, Labyrinthitis
+∞
40.9
37
*
R42
ICD-10 Finland
Dizziness and giddiness
5.8
19.9
51
133
H81.3
ICD-10 Finland
Other peripheral vertigo
39.1
11.5
14
*
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
6.0
10.7
21
41
H66.0
ICD-10 Finland
Acute suppurative otitis media
4.7
9.6
25
63
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
9.5
8.1
16
19
H81.2
ICD-10 Finland
Vestibular neuronitis
73.5
6.5
7
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.3
6.2
27
97
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
51
288
2.32
4.76
4.3
2.8
34.04
28.64
u/l
1.04
51
272
53
324
2.12
3.92
3.2
3.0
—
—
—
0
0
16
57
3.08
3.68
1.7
1.6
—
—
—
0
0
77
561
2.00
3.34
9.8
8.4
4.14
3.94
e9/l
0.29
67
483
44
265
2.03
3.29
3.3
2.9
0.54
0.30
e6/l
0.37
35
207
34
186
2.14
3.27
3.9
1.6
1.24
1.04
mg/l
0.25
28
146
67
469
1.94
3.23
3.4
3.7
0.00
0.00
estimate
-0.00
14
95
67
469
1.94
3.23
4.7
5.0
0.00
0.00
estimate
-0.00
13
91
8
18
4.67
2.84
1.6
1.2
—
—
—
0
0
66
476
1.83
2.76
3.4
3.7
0.00
0.00
estimate
-0.00
13
89
13
50
2.79
2.63
7.5
3.2
24.38
24.80
mmol/l
0.18
13
50
5
8
6.45
2.39
2.0
2.3
—
—
—
0
0
5
8
6.45
2.39
2.0
2.3
—
—
—
0
0
24
129
2.07
2.38
2.4
2.8
3.19
3.37
e6/l
0.04
15
75
17
80
2.31
2.31
2.3
2.3
487.94
364.34
nmol/l
0.71
17
74
6
13
4.79
2.30
1.7
1.6
—
—
—
0
0
7
18
4.06
2.29
2.1
1.7
—
—
—
0
0
78
614
1.74
2.24
4.3
2.8
47.93
41.55
u/l
0.33
71
581
5
9
5.73
2.23
1.4
1.0
—
—
—
0
0
5
9
5.73
2.23
2.6
1.1
—
—
—
0
0
5
10
5.16
2.09
1.4
1.1
—
—
—
0
0
5
10
5.16
2.09
1.4
1.1
—
—
—
0
0
7
20
3.65
2.09
1.1
1.1
—
—
—
0
0
7
20
3.65
2.09
2.7
1.6
—
—
—
0
0
53
384
1.67
2.01
3.5
3.7
—
—
—
0
0
7
21
3.47
1.99
2.6
1.6
—
—
—
0
0
89
741
1.73
1.95
5.3
4.2
14.51
14.62
pmol/l
0.15
83
665
87
724
1.69
1.86
5.4
3.6
13.99
11.17
mm/h
0.88
82
650
6
17
3.65
1.86
2.3
1.2
—
—
—
0
0
5
12
4.29
1.84
1.0
1.6
—
—
—
0
0
5
12
4.29
1.84
1.2
1.6
—
—
—
0
0
34
224
1.72
1.81
3.4
2.2
—
—
—
0
0
86
718
1.66
1.77
10.2
6.7
81.97
76.04
u/l
0.46
79
665
8
30
2.78
1.76
1.5
1.1
—
—
—
0
0
11
49
2.37
1.69
9.5
3.6
54.24
48.38
%
0.33
11
49
101
885
1.79
1.68
4.2
4.3
5.75
5.86
mmol/l
0.41
91
794
54
412
1.55
1.57
20.9
12.1
1.03
1.21
inr
3.28
15
129
5
15
3.43
1.54
3.0
1.9
—
—
—
0
0
5
15
3.43
1.54
3.0
1.9
—
—
—
0
0
6
21
2.95
1.52
1.7
1.2
322.50
394.48
mg/l
—
6
21
6
21
2.95
1.52
2.2
2.8
—
—
—
0
0
23
142
1.76
1.52
2.7
2.7
2.36
0.92
e6/l
1.19
15
87
106
953
1.81
1.46
23.5
12.7
25.60
22.64
mg/l
0.38
92
732
53
411
1.51
1.40
2.7
2.2
77.57
74.95
nmol/l
0.22
43
355
5
17
3.02
1.37
1.8
1.1
3.42
3.87
mmol/l
—
5
17
13
69
1.99
1.34
5.8
3.1
91.42
77.70
ng/l
0.23
13
60
5
18
2.85
1.29
1.6
1.4
4.12
7.21
u/ml
—
5
18
17
102
1.77
1.24
3.7
6.0
0.62
1.15
mmol/l
0.46
11
79
103
935
1.62
1.16
5.2
4.6
3.04
2.72
mmol/l
3.14
93
853
21
137
1.64
1.15
3.2
1.8
—
—
—
0
0
99
892
1.56
1.14
6.1
4.8
1.83
1.86
mu/l
0.10
93
806
15
89
1.78
1.14
3.1
1.6
—
—
—
0
0
15
89
1.78
1.14
3.5
1.7
—
—
—
0
0
8
41
2.02
1.11
2.0
1.5
—
—
—
0
0
75
644
1.42
1.08
3.8
3.4
—
—
—
0
0
5
22
2.32
1.04
1.6
1.8
—
—
—
0
0
5
22
2.32
1.04
6.2
1.1
0.00
0.00
g/l
—
5
22
5
22
2.32
1.04
4.4
2.3
234.80
167.73
%
—
5
22
0
29
0.00
0.99
0.0
1.6
—
—
—
0
0
7
36
2.00
0.98
1.4
1.2
—
—
—
0
0
34
258
1.44
0.96
1.5
1.7
1.30
1.32
mmol/l
0.06
29
210
7
37
1.94
0.95
1.4
1.2
—
—
—
0
0
29
214
1.46
0.94
2.1
1.6
—
—
—
0
0
11
63
1.82
0.93
3.3
3.7
4.54
4.48
pmol/l
0.08
11
55
6
28
2.20
0.93
2.7
1.4
—
—
—
0
0
11
64
1.79
0.89
1.7
1.3
—
—
—
0
0
6
30
2.05
0.88
5.3
1.1
—
—
—
0
0
6
31
1.98
0.85
2.3
1.3
0.24
0.24
g/l
—
6
31
6
32
1.92
0.83
2.3
1.3
1.19
1.21
g/l
—
6
32
97
890
1.43
0.83
18.1
12.0
81.82
82.58
ml/min/173m2
0.11
83
710
99
912
1.44
0.82
4.4
4.1
1.46
1.52
mmol/l
0.80
94
827
54
458
1.32
0.76
3.5
2.5
—
—
—
0
0
9
55
1.69
0.75
5.1
2.3
0.89
1.48
%
—
9
55
99
917
1.41
0.75
4.8
4.2
4.94
4.65
mmol/l
2.06
94
841
5
26
1.96
0.71
1.0
1.1
—
20.26
—
0
5
14
94
1.55
0.70
2.9
1.9
34.07
28.55
u/l
0.23
14
77
14
199
0.67
0.68
1.6
1.5
—
—
—
0
0
34
274
1.33
0.67
3.6
3.8
0.00
0.00
estimate
-0.00
14
89
5
29
1.75
0.64
2.2
2.0
—
—
—
0
0
92
853
1.31
0.60
5.6
5.4
40.11
39.57
mmol/mol
0.20
85
780
0
23
0.00
0.59
0.0
1.3
—
—
—
0
0
112
1072
1.50
0.57
30.6
18.7
39.23
39.76
%
0.37
106
1015
6
37
1.65
0.56
1.7
1.4
—
—
—
0
0
6
38
1.61
0.55
2.0
1.9
—
—
—
0
0
6
40
1.53
0.52
2.3
2.2
—
—
—
0
0
94
882
1.28
0.50
4.2
3.7
1.34
1.23
mmol/l
0.72
89
795
40
344
1.24
0.47
6.4
3.7
26.46
37.96
ng/l
0.48
27
239
43
375
1.23
0.45
2.1
1.8
102.26
95.63
pmol/l
0.23
21
182
5
31
1.64
0.43
1.6
1.3
—
—
—
0
0
8
59
1.38
0.42
1.1
1.0
—
—
—
0
0
12
91
1.35
0.35
2.0
3.3
—
—
—
0
0
6
89
0.66
0.34
2.0
2.1
—
—
—
0
0
14
110
1.31
0.33
2.9
2.5
0.61
0.78
ug/l
—
9
66
18
147
1.26
0.33
3.7
4.0
19.46
24.51
%
—
9
64
30
261
1.20
0.32
3.2
3.7
10.86
6.94
mg/mmol
0.24
16
161
29
252
1.20
0.31
1.4
1.3
0.69
1.16
u/ml
—
7
70
5
72
0.68
0.27
2.0
1.9
—
—
—
0
0
5
72
0.68
0.27
1.2
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
0.20
—
0
5
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
17
149
1.16
0.16
2.7
2.2
—
—
—
0
0
15
133
1.15
0.12
2.5
1.9
—
—
—
0
0
19
173
1.12
0.11
1.7
1.2
24.32
41.97
iu/ml
—
6
45
5
45
1.12
0.10
1.2
1.6
—
—
—
0
0
19
176
1.09
0.08
2.7
2.4
2.43
2.46
mmol/l
0.25
14
154
11
118
0.93
0.03
8.2
6.8
—
—
—
0
0
32
329
0.96
0.02
3.3
3.0
2.32
2.36
mmol/l
0.57
27
283
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
0.00
3.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
85
0.94
-0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
12.92
—
0
6
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
13.95
—
0
6
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
0.33
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_LABYRINTHITIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have H8_LABYRINTHITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: H8_LABYRINTHITIS – Labyrinthitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data