Scissor bite

K11_SCISS_BITE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.27
  • Hospital discharge: ICD-10 K07.27
  • Cause of death: ICD-10 K07.27

3 out of 7 registries used, show all original rules.

1063

4. Check minimum number of events

None

1063

5. Include endpoints

None

1063

6. Filter based on genotype QC (FinnGen only)

1063

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 33237 16793 16429
Only index persons 30775 15757 15018
Unadjusted period prevalence (%)
Whole population 0.47 0.48 0.46
Only index persons 0.58 0.58 0.57
Median age at first event (years)
Whole population 13.30 13.34 13.23
Only index persons 13.52 13.54 13.51

-FinnGen-

Key figures

All Female Male
Number of individuals 1063 658 405
Unadjusted period prevalence (%) 0.21 0.22 0.18
Median age at first event (years) 15.88 16.04 15.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
899
Matched controls
8954
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
+∞
323.0
899
*
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
7.3
130.5
381
823
K07.23
ICD-10 Finland
Deep bite
5.9
97.7
326
784
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
6.1
79.3
247
526
SBB10
NOMESCO Finland
Teeth copy
3.9
76.0
448
1818
SXC05
NOMESCO Finland
Other oral or dental procedure
4.2
72.6
355
1209
SJC40
NOMESCO Finland
Removal of orthodontisk device with at most 6 brackets
4.6
72.2
308
919
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.5
56.2
336
1295
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
3.8
54.2
281
961
K07.13
ICD-10 Finland
Retrognaty, mandibular
7.4
54.2
137
212
SAA04
NOMESCO Finland
Special inverstigation of mouth
3.8
51.4
262
878
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
3.5
49.9
282
1023
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.5
47.2
265
950
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
3.9
46.4
224
708
SJC50
NOMESCO Finland
Removal of orthodontisk device with at least 7 brackets
3.5
43.2
242
858
EB1MA
NOMESCO Finland
Cephalometry with X-ray
3.4
42.9
251
918
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
3.6
42.3
220
734
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
3.2
41.9
269
1053
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
33.6
39.2
51
16
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
3.4
38.1
217
770
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
4.9
37.5
132
304
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.5
37.1
546
3436
SJB60
NOMESCO Finland
External device grinding and adaptation
3.5
37.1
195
649
SJX10
NOMESCO Finland
Short check-up visit for orthodontisk therapy
2.7
35.5
313
1477
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
5.0
35.3
120
265
SAA03
NOMESCO Finland
Extended examination of mouth
2.5
34.1
654
4625
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.1
31.4
199
752
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
2.7
28.4
228
995
SJD30
NOMESCO Finland
Demanding attachment of arrow to fixed orthodontisk device
3.4
27.8
151
505
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.8
27.4
203
842
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
3.0
27.0
179
691
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
2.6
26.1
225
1018
SJX20
NOMESCO Finland
Check-up visit for orthodontisk therapy
2.7
25.8
200
849
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.1
24.9
439
2792
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
3.1
24.7
148
531
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
5.6
24.5
73
138
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
3.4
20.2
104
333
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
4.4
18.5
69
167
EBB10
NOMESCO Finland
Insertion of dental implant
13.9
18.3
31
23
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
2.6
17.9
141
594
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
2.6
17.0
130
537
SAA02
NOMESCO Finland
Basic examination of mouth
2.4
16.2
809
7080
SPB10
NOMESCO Finland
Production of temporary crone to tooth
33.9
15.7
20
6
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
4.7
15.7
54
121
SJB10
NOMESCO Finland
Fitting of loose orthodontic device with user information, demanding
2.9
15.5
99
368
EBB15
NOMESCO Finland
Insertion of dental implant abutment
18.7
14.7
22
12
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
2.1
14.0
179
950
K07.24
ICD-10 Finland
Open bite
3.5
13.4
62
183
K07.60
ICD-10 Finland
Snapping jaw
3.2
13.3
71
234
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
10.2
13.0
25
25
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
5.7
12.8
36
65
K03.00
ICD-10 Finland
Approximal wear
3.4
12.1
59
182
EEC05
NOMESCO Finland
Le Fort I osteotomy
17.2
11.2
17
10
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
2.1
11.2
132
671
OIKRV
NOMESCO Finland
NA
21.7
10.7
15
7
D19
ICPC
Teeth/gum symptom/complaint
1.7
10.6
301
2073
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
3.9
10.4
42
112
WZA90
NOMESCO Finland
Other doctors statement
1.6
10.2
315
2214
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.2
10.1
103
490
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
9.6
444
3442
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
9.6
698
6056
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.1
9.2
108
548
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
2.7
9.2
61
231
SJA04
NOMESCO Finland
Very demanding plan for orthodontic care
13.8
9.2
15
11
SJC00
NOMESCO Finland
Bracket with fixed attachment
8.4
9.1
19
23
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.6
8.9
244
1653
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
2.1
8.8
99
495
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
8.8
225
1490
SPC10
NOMESCO Finland
Attachment of standard crone of tooth
7.7
8.6
19
25
SJA03
NOMESCO Finland
Demanding plan for orthodontic care
9.1
8.5
17
19
K05.30
ICD-10 Finland
Periodontitis complex
2.6
8.5
62
251
KMAK
NOMESCO Finland
NA
1.6
8.4
259
1804
EMAK
NOMESCO Finland
NA
3.2
8.3
41
130
K07.10
ICD-10 Finland
Asymmetry of jaw
6.5
8.2
20
31
OIKK
NOMESCO Finland
NA
1.7
7.8
183
1179
SJE90
NOMESCO Finland
Finishing face of orthodontick therapy
4.2
7.8
28
68
D82
ICPC
Teeth/gum disease
1.5
7.6
356
2723
OIKH
NOMESCO Finland
NA
1.8
7.6
139
831
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
2.7
7.5
51
197
EB1WA
NOMESCO Finland
NA
6.6
7.1
17
26
OIKJA
NOMESCO Finland
NA
3.1
7.0
37
124
SXC03
NOMESCO Finland
Other oral or dental procedure
7.0
7.0
16
23
K06.18
ICD-10 Finland
Another gingival hyperplasia
5.9
6.9
18
31
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
13.8
6.9
11
8
SJD50
NOMESCO Finland
Production and attachment of palatinal or lingual arrow
2.5
6.9
54
227
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
6.8
343
2644
-1
NOMESCO Finland
NA
1.4
6.8
491
4069
SPE00
NOMESCO Finland
Fitting and preparation of metal structure partial teeth prosthesis
12.3
6.6
11
9
SPC20
NOMESCO Finland
Attachment of crone of tooth to implant
10.1
6.5
12
12
EBA00
NOMESCO Finland
Extraction of tooth
1.4
6.4
364
2866
SJX00
NOMESCO Finland
Reparation of orthodontiskt device by dentist
3.0
6.4
35
121
SJC04
NOMESCO Finland
NA
4.7
6.4
20
43
Z01.2
ICD-10 Finland
Dental examination
1.4
6.4
506
4245
WX110
NOMESCO Finland
Local anesthesy
1.5
6.3
639
5616
OIKAL
NOMESCO Finland
NA
2.0
6.1
78
412
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.7
6.1
117
709
SJC20
NOMESCO Finland
Extraoral ofthodontisk pulling device arrangement and urser information
2.5
6.1
43
173

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
259
2050
1.34
3.95
1.8
1.6
99.6
98.3
pmol/l
0.17
129
1088
306
2486
1.32
3.89
6.2
6.2
38.2
37.9
g/l
0.44
291
2359
94
636
1.52
3.45
2.0
2.2
5.5
6.4
u/l
0.40
73
474
23
107
2.17
2.95
1.0
1.2
—
—
—
0
0
87
610
1.46
2.73
1.4
1.6
308.6
361.4
mu/l
0.74
82
559
145
1117
1.34
2.63
1.5
1.5
333.8
530.9
titre
1.44
32
202
108
794
1.40
2.62
4.2
4.4
0.2
0.2
g/l
0.49
101
760
113
840
1.38
2.57
6.4
5.5
1.4
1.5
%
0.13
107
787
144
1119
1.33
2.47
3.8
3.3
8369.8
3791.4
umol/l
0.47
133
1017
17
76
2.25
2.43
1.2
1.1
—
—
—
0
0
85
608
1.43
2.42
2.0
2.1
11.7
11.8
iu/l
0.01
69
462
90
652
1.41
2.39
2.5
2.3
11.7
10.5
nmol/l
0.66
83
563
17
77
2.22
2.36
1.2
1.2
6.3
18.4
u/ml
0.81
12
62
84
603
1.42
2.35
5.9
3.8
63.1
68.1
e9/l
0.61
63
404
160
1271
1.30
2.34
3.5
3.1
2.8
4.2
e6/l
1.21
84
676
363
3175
1.21
2.27
8.2
7.4
—
—
—
0
0
375
3299
1.20
2.19
9.7
8.0
1.2
1.2
mmol/l
0.51
333
2942
88
646
1.39
2.19
1.2
1.2
—
—
—
0
0
548
5000
1.19
2.12
7.3
6.0
91.2
93.1
u/l
0.29
513
4695
237
1999
1.23
2.10
3.9
3.8
8.9
9.2
mmol/l
0.42
216
1815
183
1500
1.26
2.10
2.2
2.4
202.9
281.8
u/l
0.89
174
1441
60
417
1.46
2.03
3.6
5.1
21.7
22.2
s
0.35
54
391
329
2885
1.20
1.96
3.2
2.9
—
—
—
0
0
348
3069
1.19
1.94
11.2
8.1
1.2
1.2
mmol/l
0.47
316
2885
17
84
2.03
1.94
1.5
1.6
—
—
—
0
0
26
149
1.76
1.93
2.3
1.7
181.7
168.9
pmol/l
0.26
26
142
593
5476
1.18
1.91
4.5
4.1
7.6
8.1
mm/h
0.55
551
5077
9
34
2.65
1.86
1.4
3.5
—
—
—
0
0
148
1205
1.26
1.81
8.2
6.9
6.0
5.9
kpa
0.39
140
1163
246
2116
1.21
1.79
4.6
3.5
0.2
0.3
e6/l
0.18
176
1567
247
2127
1.20
1.78
4.5
3.4
—
—
—
0
0
147
1199
1.26
1.77
1.6
1.4
18.7
19.1
nmol/l
0.11
130
1067
320
2822
1.19
1.77
1.6
1.5
1.8
1.8
g/l
0.56
183
1594
153
1255
1.25
1.76
1.3
1.2
—
—
—
0
0
53
371
1.45
1.76
6.1
6.4
0.3
0.4
g/l
0.45
38
247
150
1229
1.25
1.74
10.7
9.0
1.2
1.2
mmol/l
0.38
141
1173
899
8642
1.24
1.73
9.0
8.1
—
—
—
0
0
146
1197
1.25
1.69
8.3
6.9
1.3
1.5
mmol/l
0.38
121
985
99
775
1.30
1.66
2.2
3.3
10.3
10.2
g/l
0.08
94
731
870
8351
1.21
1.61
11.1
9.8
20.3
21.5
mg/l
0.54
593
5839
686
6457
1.16
1.60
3.6
3.6
14.4
14.4
pmol/l
0.16
619
5810
11
50
2.20
1.56
5.9
3.0
—
—
—
0
0
226
1963
1.19
1.48
3.1
2.9
2.4
2.4
mmol/l
1.00
203
1775
9
37
2.44
1.47
1.4
1.4
—
—
—
0
0
877
8442
1.20
1.47
13.0
11.2
40.2
40.3
%
0.07
737
7150
129
1061
1.24
1.47
10.7
9.7
—
—
—
0
0
145
1208
1.23
1.47
8.3
6.9
—
7.4
—
0
7
153
1282
1.22
1.46
3.1
2.7
—
—
—
0
0
100
799
1.27
1.46
7.0
6.4
—
—
—
0
0
464
4266
1.15
1.45
3.3
3.0
105.7
65.1
ug/l
0.43
438
4032
986
9614
1.30
1.43
16.0
14.1
88.2
88.0
fl
0.86
970
9470
6
22
2.73
1.43
1.8
2.0
—
—
—
0
0
135
1121
1.23
1.41
8.1
6.7
4.8
4.9
kpa
0.23
129
1086
126
1039
1.24
1.41
10.8
7.7
0.8
0.8
mmol/l
0.34
121
990
986
9617
1.30
1.40
16.0
14.0
29.6
29.5
pg
0.57
970
9475
985
9607
1.29
1.39
16.1
14.2
261.6
264.1
e9/l
0.64
955
9277
987
9629
1.30
1.39
16.0
14.1
6.4
6.6
e9/l
1.88
954
9283
92
733
1.27
1.38
1.8
1.6
—
—
—
0
0
986
9619
1.29
1.38
16.1
14.1
4.6
4.6
e12/l
1.32
950
9275
167
1422
1.20
1.36
2.7
2.7
1.3
1.1
mg/l
0.36
116
976
197
1705
1.19
1.34
5.3
3.6
7.4
7.4
ph
0.35
25
302
26
390
0.66
1.33
1.9
2.1
—
—
—
0
0
50
367
1.37
1.33
11.3
11.3
121.6
123.8
g/l
0.29
50
354
11
54
2.04
1.32
1.1
1.1
—
—
—
0
0
258
2288
1.16
1.31
4.4
3.6
29.1
54.8
e6/l
1.09
186
1723
247
2184
1.17
1.30
1.7
1.8
—
—
—
0
0
986
9628
1.28
1.29
16.1
14.3
135.3
136.0
g/l
0.84
971
9485
128
1070
1.22
1.27
3.8
3.6
972.5
187.8
mg/l
0.69
90
781
82
652
1.27
1.27
1.6
1.6
1132.7
1122.4
nmol/l
0.04
66
513
8
35
2.29
1.26
1.0
1.3
—
—
—
0
0
11
55
2.00
1.26
1.1
1.1
—
—
—
0
0
8
156
0.51
1.25
1.1
1.2
—
—
—
0
0
538
5030
1.13
1.25
4.6
3.8
—
—
—
0
0
113
935
1.23
1.24
1.6
1.6
—
—
—
0
0
187
1625
1.18
1.22
3.3
2.6
—
—
—
0
0
305
2753
1.15
1.21
5.1
4.1
24.1
79.2
e6/l
2.91
194
1840
11
56
1.97
1.21
1.1
1.3
—
—
—
0
0
223
1968
1.16
1.21
3.0
2.3
—
—
—
0
0
16
260
0.61
1.18
1.0
1.1
—
—
—
0
0
32
223
1.44
1.15
1.6
1.9
—
62.7
—
0
26
228
2023
1.16
1.15
2.9
2.9
2.7
2.7
mg/l
0.01
199
1795
56
430
1.31
1.14
2.8
2.4
0.6
0.7
ug/l
0.24
35
245
72
573
1.27
1.13
1.3
1.4
—
—
—
0
0
200
1760
1.16
1.13
3.7
2.9
—
—
—
0
0
347
3173
1.13
1.12
1.7
1.7
2.1
2.4
u/ml
0.13
64
712
31
216
1.44
1.12
1.2
1.1
—
—
—
0
0
7
30
2.33
1.12
2.3
1.4
1.0
1.0
g/l
—
7
30
476
4439
1.12
1.11
7.8
7.0
52.9
53.2
%
0.22
447
4219
58
451
1.30
1.09
10.3
11.5
0.8
0.4
mmol/l
0.41
53
353
130
1107
1.19
1.09
4.2
4.2
16.4
9.3
mg/mmol
0.56
90
800
21
136
1.55
1.07
3.3
3.1
461.9
468.4
e6/l
0.03
16
106
21
136
1.55
1.07
3.3
3.1
0.2
0.2
e9/l
0.02
16
107
93
769
1.22
1.05
2.6
2.3
2.4
2.4
mmol/l
0.40
83
656
10
52
1.92
1.05
1.3
1.1
—
—
—
0
0
10
52
1.92
1.05
1.0
1.0
—
—
—
0
0
93
770
1.22
1.04
1.5
1.4
—
—
—
0
0
58
455
1.29
1.03
1.1
1.2
—
—
—
0
0
19
286
0.66
1.03
1.5
3.0
0.3
0.2
e6/l
0.07
19
278
66
527
1.26
1.02
17.2
15.1
1.2
1.1
mg/l
0.59
66
515
226
2024
1.14
1.01
3.2
2.6
—
—
—
0
0
23
155
1.49
1.00
1.1
1.2
0.4
2.3
u/ml
1.84
15
92
12
68
1.77
0.99
2.2
2.2
—
—
—
0
0
45
343
1.32
0.99
2.7
1.8
—
—
—
0
0
481
4512
1.11
0.98
8.0
7.2
32.3
32.3
%
0.01
451
4274
22
148
1.49
0.97
3.2
3.1
1.1
1.2
e9/l
0.40
11
99
12
69
1.74
0.95
1.3
1.3
66.4
44.2
pmol/l
—
6
14
6
27
2.22
0.93
1.3
1.5
—
—
—
0
0
113
966
1.19
0.93
7.9
6.2
7.4
7.4
ph
—
8
59
113
967
1.18
0.92
7.9
6.2
5.2
5.1
kpa
0.71
104
931
794
7673
1.12
0.90
12.3
10.3
3.9
3.9
mmol/l
0.39
755
7422
495
4669
1.11
0.89
8.4
7.1
2.0
2.0
e9/l
0.03
445
4120
106
905
1.19
0.89
3.5
2.8
23.8
23.4
%
0.11
98
814
32
236
1.36
0.89
4.7
2.8
—
—
—
0
0
8
42
1.90
0.88
2.1
2.6
—
—
—
0
0
23
160
1.44
0.88
11.3
7.0
—
—
—
0
0
84
703
1.21
0.88
1.4
1.3
—
—
—
0
0
792
7657
1.12
0.87
13.9
12.6
13.2
13.2
%
0.07
772
7503
528
5000
1.10
0.87
10.1
8.9
3.5
3.7
e9/l
1.33
457
4296
8
43
1.86
0.87
2.1
2.5
104.5
105.8
mmol/l
—
8
43
177
1579
1.14
0.85
3.0
3.3
77.5
110.2
ug/g
1.56
147
1224
175
1560
1.14
0.85
1.8
1.6
1.3
1.3
mmol/l
0.46
159
1399
793
7672
1.12
0.85
12.2
10.3
139.7
139.6
mmol/l
0.06
758
7457
26
187
1.39
0.84
4.2
2.2
1.0
1.3
g/l
0.67
26
171
8
45
1.78
0.84
2.1
2.5
3.8
3.9
mmol/l
—
8
45
106
912
1.18
0.82
1.4
1.5
400.8
8231399.0
pmol/l
0.50
88
814
72
598
1.21
0.82
12.6
9.4
1.3
1.3
mmol/l
0.00
72
561
11
65
1.69
0.81
1.6
1.7
31.9
32.5
pg
0.14
11
65
27
197
1.37
0.81
5.1
6.8
—
—
—
0
0
128
1122
1.16
0.79
1.4
1.9
—
—
—
0
0
53
429
1.24
0.77
1.5
1.6
—
—
—
0
0
127
1118
1.15
0.75
1.4
1.9
—
—
—
0
0
19
132
1.44
0.75
2.1
3.3
9.6
9.5
%
0.00
14
115
19
132
1.44
0.75
1.2
1.3
2.1
3.7
u/ml
—
9
68
12
75
1.60
0.74
1.1
1.1
256.2
288.9
mg/l
1.08
12
70
7
38
1.84
0.73
2.7
4.8
20.0
20.6
ug/l
—
7
38
7
38
1.84
0.73
1.7
1.1
—
—
—
0
0
441
4172
1.09
0.71
8.3
7.5
0.7
0.6
%
0.54
410
3952
12
76
1.58
0.71
1.3
1.4
11.4
9.7
umol/l
0.21
12
76
204
2216
0.90
0.70
2.1
2.1
—
—
—
0
0
88
758
1.17
0.70
3.7
3.7
1.5
1.6
ug/l
0.40
81
695
16
109
1.47
0.70
4.6
4.0
21.5
24.2
umol/l
0.79
16
109
209
1910
1.11
0.69
2.3
2.6
57.7
58.0
u/l
0.03
195
1774
324
3027
1.10
0.69
7.7
6.1
11.3
11.0
umol/l
0.15
306
2806
458
4346
1.09
0.68
8.4
7.5
8.4
8.2
%
0.50
427
4118
52
428
1.22
0.67
5.0
4.4
—
—
—
0
0
125
1110
1.14
0.67
1.4
1.9
—
—
—
0
0
7
43
1.63
0.66
1.1
2.0
—
—
—
0
0
57
475
1.21
0.66
1.1
1.1
2.1
3.8
u/ml
0.64
17
143
251
2322
1.10
0.66
8.0
7.5
—
—
—
0
0
329
3083
1.09
0.65
4.1
3.9
—
—
—
0
0
13
86
1.51
0.65
1.0
1.0
—
—
—
0
0
454
4314
1.08
0.65
8.2
7.3
2.9
2.9
%
0.18
423
4074
32
250
1.28
0.64
1.3
1.2
—
—
—
0
0
185
2009
0.90
0.64
3.0
2.7
—
—
—
0
0
760
7378
1.09
0.64
4.3
4.1
1.8
2.0
mu/l
0.96
704
6938
204
1871
1.11
0.63
6.6
5.5
90.0
89.6
%
0.10
197
1843
5
29
1.72
0.63
5.4
3.0
—
—
—
0
0
117
1039
1.14
0.63
1.4
1.9
—
—
—
0
0
33
261
1.27
0.61
13.0
14.6
—
—
—
0
0
9
136
0.66
0.61
1.0
1.5
—
—
—
0
0
20
147
1.36
0.61
1.2
1.2
3.0
7.1
u/ml
0.57
15
72
10
151
0.66
0.60
2.1
1.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.7
—
—
—
0
0
8
52
1.54
0.59
6.7
8.2
—
—
—
0
0
421
4004
1.08
0.58
6.0
5.0
6.2
6.2
mmol/l
0.02
386
3699
55
465
1.19
0.57
1.4
1.4
—
—
—
0
0
10
148
0.67
0.56
2.5
3.0
30.7
25.7
mg/l
—
5
95
16
115
1.39
0.55
3.4
2.9
565.0
667.8
e6/l
—
6
19
486
4653
1.07
0.55
8.9
7.5
0.2
0.2
e9/l
0.28
431
4094
823
8038
1.09
0.55
14.1
12.3
334.0
334.3
g/l
0.38
815
7952
15
107
1.40
0.54
1.1
1.4
—
—
—
0
0
428
4083
1.07
0.54
2.8
2.6
—
—
—
0
0
207
1919
1.09
0.53
7.2
4.5
1.1
1.1
inr
0.39
55
626
838
8196
1.09
0.52
11.7
9.9
67.3
66.4
umol/l
0.31
838
8191
6
97
0.61
0.52
6.7
4.1
3.2
1.1
%
—
6
77
96
855
1.13
0.52
5.5
5.1
6.5
7.1
umol/l
0.18
84
724
9
134
0.67
0.52
1.1
1.5
2.6
2.5
g/l
—
9
108
9
134
0.67
0.52
1.1
1.5
0.3
0.4
g/l
—
9
108
9
134
0.67
0.52
1.1
1.5
6.3
6.3
g/l
—
9
108
10
66
1.51
0.52
1.0
1.4
—
—
nmol/l
—
0
0
30
241
1.25
0.51
1.3
1.2
—
—
—
0
0
59
508
1.17
0.51
1.2
1.2
—
28.3
—
0
19
471
4516
1.07
0.51
8.7
7.2
0.5
0.5
e9/l
0.02
411
3893
472
4526
1.07
0.51
8.7
7.2
0.0
0.0
e9/l
0.15
411
3903
147
1344
1.10
0.51
4.5
4.0
—
—
—
0
0
9
65
1.38
0.50
5.3
1.2
20.1
11.6
u/l
—
9
59
7
45
1.55
0.49
1.1
1.2
—
—
—
0
0
50
427
1.17
0.48
4.3
3.1
—
—
—
0
0
20
254
0.78
0.47
1.1
1.1
—
—
—
0
0
7
48
1.46
0.46
1.3
1.6
4.4
7.1
u/l
—
7
39
54
466
1.16
0.46
2.3
1.7
197.6
191.6
u/ml
0.06
26
220
23
182
1.26
0.45
3.6
3.7
3.4
3.5
e9/l
0.14
23
182
285
2696
1.07
0.45
2.3
2.0
—
—
—
0
0
23
183
1.26
0.44
3.9
4.1
50.9
52.6
%
0.33
23
183
7
51
1.37
0.44
1.1
1.2
—
—
—
0
0
12
86
1.39
0.44
17.4
9.0
11.3
12.3
%
0.30
12
86
5
31
1.61
0.43
1.0
1.2
—
—
—
0
0
5
31
1.61
0.43
1.2
1.3
—
—
—
0
0
5
31
1.61
0.43
1.0
1.2
—
—
—
0
0
5
31
1.61
0.43
1.0
1.2
—
—
—
0
0
85
764
1.12
0.42
8.0
6.3
10.1
9.8
kpa
0.88
77
735
630
6124
1.06
0.42
3.1
2.9
5.5
5.5
mmol/l
0.01
575
5676
27
221
1.22
0.41
2.4
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
3.8
—
4.3
—
0
15
18
140
1.29
0.41
1.1
1.1
—
—
—
0
0
11
149
0.73
0.41
3.0
3.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
143
1326
1.09
0.39
1.7
1.6
—
—
—
0
0
176
1864
0.93
0.38
4.2
3.2
0.0
0.0
estimate
1.08
59
677
5
36
1.39
0.38
2.2
1.9
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
106
971
1.10
0.38
3.0
3.4
476.7
863.0
ng/l
0.62
58
535
70
774
0.89
0.38
1.2
1.3
—
—
—
0
0
62
552
1.13
0.37
1.3
1.4
—
—
—
0
0
178
1670
1.07
0.36
2.6
2.5
30.3
27.9
ng/l
0.07
99
709
9
70
1.28
0.36
1.4
1.6
—
—
—
0
0
116
1070
1.09
0.36
1.1
1.2
10.9
8.8
u/ml
0.09
33
383
16
125
1.28
0.36
9.7
4.2
1.2
1.5
mmol/l
1.53
16
120
84
763
1.11
0.36
1.7
2.3
—
—
—
0
0
11
81
1.36
0.35
1.0
1.4
—
—
—
0
0
88
802
1.10
0.35
1.4
1.4
346.0
319.7
u/ml
0.09
83
746
9
121
0.74
0.35
1.6
2.7
—
—
—
0
0
12
90
1.33
0.35
3.3
3.5
769.4
200.9
u/ml
—
5
24
18
144
1.25
0.34
1.1
1.1
—
—
—
0
0
10
73
1.37
0.34
2.0
2.5
—
—
—
0
0
6
45
1.33
0.33
1.3
1.2
—
0.2
—
0
11
6
45
1.33
0.33
1.7
1.0
1748.9
1449.7
miu/ml
—
6
45
163
1531
1.07
0.33
4.0
2.9
7.3
7.5
e6/l
0.08
134
1346
6
46
1.30
0.33
1.0
1.0
—
20.1
—
0
13
16
127
1.26
0.33
1.1
1.1
1.0
1.2
u/ml
—
7
24
372
3585
1.05
0.32
5.1
4.3
0.0
0.0
estimate
0.50
62
698
372
3588
1.05
0.31
3.6
3.0
0.0
0.0
estimate
0.00
59
669
16
128
1.25
0.31
1.8
1.3
—
—
—
0
0
7
52
1.34
0.31
1.0
1.2
—
—
—
0
0
18
147
1.22
0.30
1.0
1.1
—
—
—
0
0
11
84
1.31
0.29
1.2
1.2
—
—
—
0
0
12
93
1.29
0.29
3.3
1.7
13.4
13.1
%
0.49
12
93
37
325
1.14
0.28
1.6
1.6
1.1
1.2
g/l
0.81
37
311
118
1103
1.07
0.28
1.4
1.9
—
—
—
0
0
100
930
1.08
0.28
2.2
2.3
352.7
377.3
nmol/l
0.74
88
873
15
121
1.24
0.28
2.1
3.4
209.0
241.8
e6/l
—
10
84
12
150
0.79
0.27
8.1
5.9
5.0
5.0
kpa
0.15
12
150
587
5957
0.96
0.27
3.7
3.4
2.6
2.7
mmol/l
0.94
544
5611
30
261
1.15
0.27
3.1
4.0
5.0
8.0
umol/l
1.68
23
216
17
140
1.21
0.26
1.9
1.9
116.1
143.8
ng/l
0.98
17
128
40
445
0.89
0.26
1.0
1.1
—
—
—
0
0
108
1010
1.07
0.26
1.8
1.5
—
—
—
0
0
36
318
1.13
0.26
1.6
1.6
0.2
0.2
g/l
0.54
36
305
31
271
1.14
0.26
2.7
2.1
25.5
39.1
u/ml
0.61
31
260
53
480
1.11
0.26
1.1
1.1
0.7
1.5
u/ml
1.47
40
298
5
74
0.67
0.26
1.4
1.6
—
—
—
0
0
29
329
0.87
0.25
1.4
1.2
—
—
—
0
0
198
1891
1.05
0.25
1.8
1.7
—
—
—
0
0
59
639
0.92
0.24
4.9
3.4
—
—
—
0
0
54
492
1.10
0.24
1.1
1.1
15.0
10.0
u/ml
0.71
40
331
6
85
0.70
0.24
5.7
5.1
2.6
1.3
ug/l
—
6
85
29
255
1.14
0.23
1.7
1.6
—
—
—
0
0
24
208
1.15
0.23
7.8
9.0
24.6
23.9
mmol/l
0.52
24
193
20
171
1.17
0.22
1.3
1.4
274.1
343.2
ug/g
—
9
82
12
97
1.24
0.22
2.3
2.2
—
—
—
0
0
581
5881
0.97
0.22
3.5
3.2
1.4
1.4
mmol/l
0.22
535
5560
5
41
1.22
0.22
1.0
1.0
—
4.6
iu/ml
—
0
5
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.1
—
0.4
—
0
11
0
11
0.00
0.21
0.0
3.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
8
103
0.77
0.21
1.3
2.4
293.8
295.0
mosm/kgh2o
—
8
82
5
43
1.16
0.21
1.4
1.2
189.6
490.7
u/l
—
5
37
16
135
1.18
0.21
3.9
2.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
20
173
1.15
0.20
16.9
5.1
—
—
—
0
0
22
249
0.88
0.20
3.2
2.4
—
—
—
0
0
6
49
1.22
0.20
4.7
3.9
167.0
133.2
ug/l
—
6
49
153
1464
1.05
0.19
4.0
2.9
626.8
613.6
mosm/kgh2o
0.24
125
1268
53
490
1.08
0.19
1.7
2.0
4.2
4.1
e9/l
0.13
44
429
370
3608
1.03
0.18
3.6
3.1
0.0
0.0
estimate
0.00
61
674
10
81
1.23
0.18
1.2
1.6
—
—
—
0
0
58
540
1.07
0.18
4.4
4.4
0.6
0.4
%
0.37
14
116
7
62
1.13
0.17
1.6
1.5
—
—
—
0
0
5
67
0.74
0.17
1.0
1.1
—
—
—
0
0
162
1670
0.96
0.17
1.8
1.8
—
—
—
0
0
17
193
0.88
0.16
1.9
1.9
2860.7
5.2
iu/l
—
7
70
8
70
1.14
0.16
2.3
1.6
—
—
—
0
0
171
1758
0.96
0.16
3.2
2.9
1.0
1.0
kg/l
1.83
18
237
24
215
1.11
0.15
1.0
1.1
—
—
—
0
0
61
573
1.06
0.15
4.6
4.9
0.9
0.6
%
0.49
15
158
13
150
0.86
0.15
8.2
5.6
9.5
9.4
kpa
0.08
13
150
54
571
0.94
0.14
1.9
1.8
—
—
—
0
0
45
419
1.07
0.14
1.2
1.3
260.8
255.1
miu/ml
0.03
19
193
94
897
1.05
0.14
1.5
1.9
—
—
—
0
0
7
90
0.77
0.14
1.3
1.1
—
—
—
0
0
16
140
1.14
0.14
4.2
5.2
—
—
—
0
0
16
140
1.14
0.14
5.2
3.4
3.2
4.4
u/ml
0.69
16
130
8
98
0.81
0.13
1.1
1.3
—
—
—
0
0
12
103
1.16
0.13
4.5
4.4
—
—
—
0
0
57
538
1.06
0.13
1.5
2.3
—
—
—
0
0
15
132
1.13
0.12
1.7
1.9
—
—
—
0
0
15
132
1.13
0.12
1.7
1.9
—
—
—
0
0
28
257
1.09
0.12
1.0
1.1
0.5
0.7
u/ml
0.21
11
81
57
540
1.05
0.12
4.8
5.0
0.1
0.1
%
0.14
14
143
58
550
1.05
0.11
1.2
1.2
3.1
3.6
u/ml
0.13
37
307
90
930
0.96
0.11
2.9
2.2
13389.6
6678.0
u/l
0.65
21
280
15
133
1.13
0.11
1.7
1.9
—
—
—
0
0
15
133
1.13
0.11
1.7
1.9
—
—
—
0
0
37
392
0.94
0.11
7.0
4.6
1.2
1.2
mmol/l
0.31
31
348
24
220
1.09
0.11
1.0
1.1
—
—
—
0
0
26
240
1.08
0.10
1.4
1.5
—
—
—
0
0
24
221
1.08
0.10
1.0
1.1
—
—
—
0
0
17
154
1.10
0.09
1.1
1.7
—
—
—
0
0
6
55
1.09
0.08
1.2
1.1
143.8
243.1
iu/ml
—
6
55
11
97
1.13
0.08
1.5
1.2
—
—
—
0
0
78
802
0.97
0.08
1.2
1.3
101.8
134.1
iu/ml
0.43
26
275
7
67
1.04
0.08
1.0
1.2
—
—
—
0
0
6
70
0.85
0.07
1.7
1.1
—
—
—
0
0
55
528
1.04
0.07
4.6
5.0
0.0
0.0
%
0.50
14
126
29
273
1.06
0.07
4.7
4.0
4.6
24.9
ug/l
0.61
19
201
18
166
1.08
0.07
6.2
8.3
—
—
—
0
0
9
83
1.08
0.07
8.2
3.3
—
—
—
0
0
530
5244
1.01
0.07
3.9
3.8
36.9
37.3
mmol/mol
0.37
496
4965
19
176
1.08
0.07
1.2
2.0
—
—
—
0
0
9
88
1.02
0.07
2.2
1.7
—
—
—
0
0
50
516
0.96
0.06
1.3
1.3
—
—
—
0
0
196
1926
1.02
0.06
5.5
4.5
—
—
—
0
0
79
806
0.97
0.05
1.8
2.0
—
—
—
0
0
21
197
1.06
0.05
1.4
1.5
—
—
—
0
0
410
4114
0.99
0.05
10.6
8.8
0.0
0.0
e9/l
0.33
329
3278
11
100
1.10
0.05
8.9
3.2
—
—
—
0
0
203
2044
0.99
0.04
1.5
1.6
—
—
—
0
0
26
248
1.05
0.04
1.5
1.5
—
—
—
0
0
566
5660
0.99
0.03
3.3
3.0
1.1
1.2
mmol/l
0.83
524
5359
25
239
1.04
0.03
1.4
1.5
—
—
—
0
0
21
219
0.95
0.03
1.4
1.1
—
—
—
0
0
114
1121
1.01
0.03
1.2
1.2
12.9
22.5
iu/ml
2.47
30
304
13
121
1.07
0.03
1.1
1.1
—
—
—
0
0
71
695
1.02
0.03
1.5
1.4
—
—
—
0
0
259
2595
0.99
0.02
1.5
1.6
—
—
—
0
0
598
5973
0.99
0.02
3.6
3.2
4.5
4.5
mmol/l
0.29
556
5672
10
107
0.93
0.02
13.1
6.7
—
—
—
0
0
21
217
0.96
0.02
1.9
1.8
—
—
—
0
0
23
223
1.03
0.00
2.2
2.8
—
—
—
0
0
34
333
1.02
0.00
1.1
1.1
6.0
5.5
u/ml
0.05
19
170
24
242
0.99
0.00
2.0
2.6
11.9
18.0
e6/l
0.24
18
185
46
457
1.00
0.00
1.2
1.2
—
—
—
0
0
12
125
0.96
0.00
1.0
1.1
—
—
—
0
0
29
286
1.01
0.00
1.5
1.6
—
—
—
0
0
19
193
0.98
0.00
1.1
1.2
232.4
231.7
iu/ml
—
9
59
15
149
1.00
0.00
4.1
4.6
410.9
387.3
umol/l
0.32
15
135
30
296
1.01
0.00
1.0
1.1
22.7
9.1
u/ml
1.08
16
168
10
99
1.01
0.00
1.4
1.1
—
—
—
0
0
18
179
1.00
0.00
7.8
4.6
—
—
—
0
0
11
106
1.03
0.00
2.5
3.1
—
—
—
0
0
38
384
0.99
0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
5
54
0.92
0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
5
59
0.84
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
13.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.7
—
19.3
—
0
6
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
13.1
—
—
—
0
0
7
73
0.96
0.00
1.9
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
8
81
0.98
0.00
1.9
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
9
95
0.94
0.00
5.4
3.8
3.8
3.9
mmol/l
—
9
84

Mortality – FinRegistry

Association

Association between endpoint K11_SCISS_BITE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_SCISS_BITE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_SCISS_BITE – Scissor bite

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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