Scissor bite

K11_SCISS_BITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.27
  • Hospital discharge: ICD-10 K07.27
  • Cause of death: ICD-10 K07.27

3 out of 7 registries used, show all original rules.

1114

4. Check minimum number of events

None

1114

5. Include endpoints

None

1114

6. Filter based on genotype QC (FinnGen only)

1048

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 33237 16793 16429
Only index persons 30775 15757 15018
Unadjusted period prevalence (%)
Whole population 0.47 0.48 0.46
Only index persons 0.58 0.58 0.57
Median age at first event (years)
Whole population 13.30 13.34 13.23
Only index persons 13.52 13.54 13.51

-FinnGen-

Key figures

All Female Male
Number of individuals 1048 646 402
Unadjusted period prevalence (%) 0.21 0.23 0.18
Median age at first event (years) 16.00 16.13 15.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1114
Matched controls
11021
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
+∞
307.7
1114
*
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
7.1
219.3
471
1036
K07.23
ICD-10 Finland
Deep bite
5.5
148.6
390
990
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
6.2
145.3
308
644
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
4.6
118.4
390
1165
SXC05
NOMESCO Finland
Other oral or dental procedure
4.0
109.7
468
1675
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
36.6
99.6
63
18
SBB10
NOMESCO Finland
Dental impressions
3.5
92.0
549
2393
K07.13
ICD-10 Finland
Retrognaty, mandibular
6.7
91.2
158
265
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
3.5
74.8
344
1247
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
3.5
74.5
353
1304
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.2
70.6
400
1638
EB1MA
NOMESCO Finland
Cephalometry with X-ray
3.4
69.0
316
1136
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
3.6
66.7
272
906
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.3
64.3
315
1175
SAA04
NOMESCO Finland
Special examination of mouth
3.3
62.3
302
1117
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
4.7
62.1
157
368
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
3.2
58.2
293
1104
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.4
57.2
257
903
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.0
56.6
133
293
SJC10
NOMESCO Finland
Orthodontic band in one tooth
3.2
55.5
271
1000
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
2.9
51.7
323
1364
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
2.6
45.7
377
1816
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
3.1
45.1
229
856
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
3.4
44.5
186
618
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
43.8
692
4445
SAA03
NOMESCO Finland
Extended examination of mouth
2.7
43.5
838
5882
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
3.0
43.1
228
870
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
2.6
40.4
289
1288
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
2.9
40.3
226
888
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
2.7
38.5
244
1021
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
2.6
37.4
282
1284
EBB10
NOMESCO Finland
Insertion of dental implant
13.1
37.1
36
28
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.7
36.5
238
1008
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
31.8
603
3966
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
3.0
30.6
147
526
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.6
29.6
192
805
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
4.6
29.6
73
166
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.8
29.3
96
270
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
3.7
24.9
83
236
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
2.6
24.6
164
694
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
2.5
24.1
166
713
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
7.7
21.9
31
41
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
2.7
21.4
122
476
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
5.5
20.1
39
72
SAE01, ,
NOMESCO Finland
6.6
18.6
30
46
K07.60
ICD-10 Finland
Snapping jaw
2.8
18.2
94
348
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
2.2
17.3
160
777
K07.10
ICD-10 Finland
Asymmetry of jaw
7.6
16.8
24
32
EBB15
NOMESCO Finland
Insertion of dental implant abutment
16.8
16.0
25
15
K07.24
ICD-10 Finland
Open bite
3.1
15.8
69
232
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
14.7
546
4059
OIKRV, ,
NOMESCO Finland
21.1
14.6
21
10
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
1.9
14.5
212
1213
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
17.1
14.2
22
13
SAA02
NOMESCO Finland
Basic examination of mouth
2.3
13.9
1016
9039
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
12.7
13.8
24
19
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
3.5
13.4
47
138
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
2.6
13.4
77
301
EEC05
NOMESCO Finland
Le Fort I osteotomy
21.2
13.3
19
9
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
2.8
12.9
65
237
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.0
12.6
142
740
K05.30
ICD-10 Finland
Periodontitis complex
2.4
12.4
86
368
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
3.1
12.2
50
162
K03.00
ICD-10 Finland
Approximal wear
2.3
11.9
97
445
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
11.6
389
2779
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.0
11.4
131
687
WYA10
NOMESCO Finland
Emergency care or similar visit
2.0
11.2
120
615
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
17.1
11.1
17
10
SDA05
NOMESCO Finland
Very demanding periodontal treatment
2.2
11.0
94
441
EMAK, ,
NOMESCO Finland
3.0
10.8
47
158
D19
ICPC
Teeth/gum symptom/complaint
1.6
10.7
401
2924
SDA03
NOMESCO Finland
Periodontal treatment
1.6
10.5
373
2685
SPC10
NOMESCO Finland
Standard dental crown
8.8
10.2
21
24
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
2.3
10.2
78
349
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
9.9
904
7946
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
2.7
9.8
53
201
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
3.8
9.4
28
74
SXC03
NOMESCO Finland
Other oral or dental procedure
9.5
9.2
18
19
K06.18
ICD-10 Finland
Another gingival hyperplasia
4.9
9.2
20
41
Z01.2
ICD-10 Finland
Dental examination
1.5
9.2
703
5885
SAE02, ,
NOMESCO Finland
3.8
9.1
27
71
D82
ICPC
Teeth/gum disease
1.5
8.9
489
3824
SPC20
NOMESCO Finland
Implant borne crown
18.6
8.9
13
7
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
8.2
8.5
18
22
OIKK, ,
NOMESCO Finland
1.6
8.5
220
1462
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
8.5
848
7430
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
8.3
501
3971
EB1S1
NOMESCO Finland
Photography of teeth
3.6
8.2
26
72
SJE90
NOMESCO Finland
Orthodontic finishing
3.2
8.1
32
102
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
8.1
315
2290
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
4.7
8.0
18
38
EB1TW
NOMESCO Finland
3D modelling of dentition
8.9
8.0
16
18
EB1WA, ,
NOMESCO Finland
6.3
8.0
20
32
OIKH, ,
NOMESCO Finland
1.7
7.9
167
1055
K07.61
ICD-10 Finland
Cracking jaw joint
2.6
7.8
43
166
EBA00
NOMESCO Finland
Extraction of tooth
1.4
7.8
518
4169
G47.3
ICD-10 Finland
Sleep apnoea
1.8
7.2
116
679
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
29.9
7.1
9
*
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.6
6.9
173
1138
OIKKK, ,
NOMESCO Finland
3.2
6.7
26
82
KMAK, ,
NOMESCO Finland
1.5
6.7
292
2161
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
8.1
6.3
13
16
SCA01
NOMESCO Finland
Preventive oral health care, short
1.4
6.1
746
6536
SPA02
NOMESCO Finland
Preparation for dental prosthetics
3.2
6.1
23
72

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
25
91
2.76
5.12
28.0
44.3
6.53
6.73
ug/l
0.21
20
82
327
2608
1.34
4.55
6.5
6.3
38.24
37.87
g/l
0.61
310
2480
102
660
1.58
4.36
1.9
2.1
5.43
6.29
u/l
0.46
76
485
269
2136
1.32
3.78
1.8
1.6
99.11
98.10
pmol/l
0.14
136
1133
120
835
1.47
3.69
4.6
4.3
0.23
0.22
g/l
0.35
112
800
181
1363
1.37
3.59
3.6
3.0
0.64
0.99
e6/l
1.82
104
736
124
886
1.43
3.34
6.7
5.6
1.44
1.50
%
0.24
118
830
94
641
1.49
3.22
1.9
2.1
12.07
12.40
iu/l
0.04
75
480
98
675
1.48
3.20
2.4
2.3
10.89
10.05
nmol/l
0.44
93
615
26
124
2.10
3.07
5.2
7.9
38.36
64.72
g/mol
0.54
21
112
92
636
1.47
2.96
6.0
3.9
63.06
68.20
e9/l
0.68
68
426
154
1168
1.35
2.93
1.5
1.5
338.29
524.81
titre
1.44
35
208
582
5208
1.22
2.78
7.2
6.0
94.52
94.02
u/l
0.06
546
4898
403
3479
1.23
2.73
10.0
8.3
1.22
1.22
mmol/l
0.60
359
3121
89
626
1.44
2.64
1.4
1.6
304.54
360.07
mu/l
0.82
84
573
165
1284
1.32
2.64
8.7
7.3
5.97
5.91
kpa
0.42
157
1242
153
1179
1.33
2.63
4.1
3.4
7707.76
3907.38
umol/l
0.41
145
1083
345
2941
1.23
2.61
1.6
1.6
1.77
1.84
g/l
0.48
195
1648
11
35
3.13
2.61
1.4
3.5
—
—
—
0
0
904
8502
1.28
2.59
9.9
8.3
24.68
26.29
u/l
1.81
871
8235
163
1275
1.31
2.52
8.7
7.4
1.33
1.49
mmol/l
0.29
140
1054
59
389
1.53
2.42
5.8
6.7
0.27
0.42
g/l
0.59
43
260
170
1347
1.29
2.39
3.6
3.2
2.76
3.96
e6/l
1.13
91
722
628
5713
1.20
2.37
4.6
4.1
7.59
8.07
mm/h
0.61
586
5298
249
2080
1.24
2.25
3.9
3.9
8.77
9.14
mmol/l
0.49
233
1913
162
1287
1.29
2.24
8.8
7.4
—
7.35
—
0
7
373
3248
1.20
2.23
11.5
8.4
1.23
1.22
mmol/l
0.67
342
3065
166
1325
1.28
2.21
1.3
1.2
—
—
—
0
0
194
1579
1.26
2.21
2.2
2.4
198.58
288.22
u/l
1.13
185
1515
93
685
1.37
2.17
1.2
1.2
—
—
—
0
0
164
1315
1.27
2.11
11.0
9.2
1.24
1.22
mmol/l
0.49
154
1259
944
8981
1.26
2.08
9.1
8.2
—
—
—
0
0
144
1141
1.29
2.04
11.1
10.0
—
—
—
0
0
63
439
1.44
2.02
4.6
5.4
21.68
22.18
s
0.35
57
412
17
83
2.04
1.96
1.2
1.1
—
—
—
0
0
106
812
1.32
1.94
2.3
3.4
10.23
10.16
g/l
0.09
101
765
18
91
1.97
1.90
1.8
1.6
—
—
—
0
0
149
1199
1.26
1.88
8.7
7.1
4.88
4.93
kpa
0.11
143
1163
721
6710
1.18
1.87
3.6
3.6
14.36
14.37
pmol/l
0.04
653
6048
374
3306
1.18
1.83
1.6
1.7
1.97
2.33
u/ml
0.19
69
735
36
229
1.57
1.79
1.7
1.9
—
63.33
—
0
27
12
53
2.25
1.77
5.8
3.0
—
—
—
0
0
75
555
1.36
1.74
18.3
16.3
1.16
1.09
mg/l
0.57
75
543
111
872
1.29
1.71
7.1
6.5
—
—
—
0
0
8
175
0.45
1.71
1.1
1.2
—
—
—
0
0
163
1341
1.24
1.70
3.1
2.7
—
—
—
0
0
152
1243
1.24
1.68
1.6
1.4
18.98
19.01
nmol/l
0.01
134
1107
1036
10016
1.33
1.68
17.0
14.6
40.34
40.90
%
0.60
982
9506
26
155
1.68
1.67
2.3
1.7
181.73
169.70
pmol/l
0.25
26
148
486
4411
1.16
1.67
3.3
3.0
102.82
65.67
ug/l
0.41
460
4169
372
3309
1.17
1.66
3.5
2.9
69.17
68.41
nmol/l
0.23
344
3088
51
356
1.44
1.66
2.7
1.8
—
—
—
0
0
239
2049
1.20
1.65
3.0
2.9
2.39
2.37
mmol/l
0.83
217
1858
8
31
2.56
1.64
2.1
1.4
0.96
1.06
g/l
—
8
31
259
2240
1.19
1.62
4.8
3.5
0.23
0.26
e6/l
0.10
189
1671
356
3163
1.17
1.61
3.2
2.9
5.75
6.05
ph
1.13
24
295
17
90
1.88
1.61
1.2
1.2
6.33
17.99
u/ml
0.88
12
74
37
244
1.52
1.60
3.8
2.9
—
—
—
0
0
1037
10035
1.32
1.59
16.6
14.4
6.43
6.60
e9/l
2.38
1002
9667
1036
10025
1.32
1.58
16.5
14.3
88.16
87.96
fl
0.80
1019
9877
260
2255
1.18
1.58
4.7
3.5
—
—
—
0
0
202
1714
1.20
1.56
3.3
2.6
—
—
—
0
0
1035
10017
1.31
1.55
16.6
14.4
262.13
264.35
e9/l
0.57
1003
9665
1036
10028
1.32
1.55
16.5
14.3
29.54
29.49
pg
0.50
1019
9882
1036
10030
1.31
1.53
16.6
14.3
4.60
4.62
e12/l
1.09
998
9662
135
1102
1.24
1.53
11.3
8.1
0.81
0.82
mmol/l
0.64
128
1055
912
8712
1.20
1.53
11.4
10.0
20.51
21.73
mg/l
0.53
621
6097
121
976
1.25
1.52
1.6
1.6
—
—
—
0
0
489
4465
1.15
1.51
9.4
7.7
—
—
—
0
0
238
2061
1.18
1.47
3.0
2.3
—
—
—
0
0
1036
10039
1.30
1.44
16.7
14.5
135.39
135.92
g/l
0.66
1020
9891
852
8105
1.17
1.44
14.3
12.8
13.93
13.65
%
0.92
833
7960
208
1785
1.19
1.43
5.3
3.7
7.39
7.39
ph
0.28
27
315
27
405
0.65
1.41
2.0
2.1
—
—
—
0
0
12
59
2.02
1.40
1.1
1.2
—
—
—
0
0
259
2271
1.17
1.37
1.8
1.8
—
—
—
0
0
6
23
2.59
1.35
1.8
2.0
—
—
—
0
0
97
777
1.26
1.32
1.8
1.6
—
—
—
0
0
243
2130
1.16
1.30
3.2
2.7
—
—
—
0
0
506
4667
1.13
1.29
8.6
7.2
52.49
53.07
%
0.54
477
4445
191
1643
1.18
1.28
3.1
3.2
74.78
108.60
ug/g
1.79
158
1284
17
276
0.60
1.27
1.0
1.2
—
—
—
0
0
43
309
1.39
1.25
11.0
5.9
0.59
0.65
%
0.57
43
309
11
55
1.99
1.24
1.3
1.1
—
—
—
0
0
11
55
1.99
1.24
1.0
1.0
—
—
—
0
0
172
1472
1.18
1.23
3.1
2.8
1.25
1.10
mg/l
0.29
119
1013
85
678
1.26
1.21
1.6
1.6
1112.85
1127.13
nmol/l
0.05
69
532
52
388
1.34
1.21
11.1
11.8
121.21
123.77
g/l
0.36
52
378
239
2108
1.15
1.18
3.1
2.9
2.70
2.72
mg/l
0.03
209
1872
8
38
2.09
1.17
1.0
1.3
—
—
—
0
0
38
272
1.40
1.15
12.3
14.5
24.82
24.07
mmol/l
1.07
38
272
511
4741
1.12
1.14
8.8
7.4
32.63
32.30
%
0.29
482
4515
838
8008
1.14
1.14
12.7
10.6
3.89
3.90
mmol/l
0.23
798
7746
133
1122
1.20
1.13
3.8
3.6
931.75
179.31
mg/l
0.69
94
831
211
1850
1.16
1.13
3.7
2.9
—
—
—
0
0
59
454
1.30
1.13
1.5
1.6
—
—
—
0
0
33
232
1.42
1.10
1.2
1.1
—
—
—
0
0
125
1051
1.20
1.10
7.9
6.4
7.41
7.40
ph
—
9
63
125
1052
1.20
1.09
8.0
6.4
5.18
5.11
kpa
0.81
116
1019
11
58
1.89
1.09
1.1
1.1
—
—
—
0
0
837
8007
1.14
1.09
12.5
10.5
139.66
139.63
mmol/l
0.17
801
7781
527
4909
1.12
1.08
9.1
7.3
2.06
2.05
e9/l
0.07
476
4344
87
707
1.24
1.08
11.4
8.0
105.38
104.94
mmol/l
0.53
87
707
61
475
1.29
1.08
10.2
11.8
0.82
0.50
mmol/l
0.35
55
380
13
73
1.77
1.07
2.1
2.2
—
—
—
0
0
98
807
1.22
1.07
2.5
2.3
2.42
2.41
mmol/l
0.33
88
690
52
397
1.31
1.06
1.1
1.1
1.59
8.68
u/ml
—
7
49
136
1158
1.18
1.05
4.2
4.1
15.62
9.15
mg/mmol
0.53
95
840
11
59
1.85
1.04
1.1
1.1
—
—
—
0
0
35
252
1.39
1.04
1.1
1.1
4.92
3.14
u/ml
0.38
16
85
270
2423
1.14
1.04
4.6
3.6
38.68
53.05
e6/l
0.38
196
1826
274
2462
1.13
1.03
9.2
7.6
—
—
—
0
0
273
2453
1.13
1.03
4.6
3.7
30.74
31.63
u/l
0.18
263
2353
9
46
1.94
1.03
2.0
2.5
—
—
—
0
0
803
7674
1.13
1.02
4.3
4.1
1.79
2.04
mu/l
0.98
743
7219
22
145
1.51
1.02
4.0
3.3
447.65
461.38
e6/l
0.07
17
113
22
145
1.51
1.02
4.0
3.3
0.17
0.18
e9/l
0.12
17
114
559
5238
1.11
1.01
10.9
9.1
3.49
3.71
e9/l
1.96
487
4497
9
47
1.90
1.01
2.0
2.5
104.33
105.83
mmol/l
—
9
47
562
5268
1.11
1.01
4.7
3.8
—
—
—
0
0
90
743
1.22
0.98
1.4
1.3
—
—
—
0
0
9
49
1.82
0.97
2.0
2.4
3.83
3.99
mmol/l
—
9
49
21
303
0.68
0.97
1.4
3.2
0.25
0.22
e6/l
0.05
21
295
221
1968
1.14
0.96
7.0
5.6
89.99
89.43
%
0.14
213
1938
28
197
1.42
0.96
4.0
2.2
1.04
1.26
g/l
0.67
28
179
58
457
1.27
0.96
2.8
2.5
0.62
0.68
ug/l
0.29
37
258
60
477
1.26
0.93
1.1
1.2
—
—
—
0
0
77
631
1.22
0.91
12.1
10.0
1.30
1.34
mmol/l
0.13
77
620
344
3157
1.11
0.90
8.0
6.2
11.27
11.40
umol/l
0.07
324
2932
318
2908
1.11
0.89
5.3
4.1
23.20
79.27
e6/l
3.18
205
1947
488
4564
1.10
0.89
9.2
7.7
8.37
8.24
%
0.43
457
4327
469
4378
1.10
0.88
9.2
7.7
0.67
0.66
%
0.25
438
4150
112
955
1.18
0.88
3.5
2.9
23.83
23.28
%
0.15
103
863
61
491
1.24
0.86
2.3
1.7
213.00
190.11
u/ml
0.21
30
230
111
948
1.18
0.86
1.5
1.5
408.37
7948247.88
pmol/l
0.50
93
843
484
4531
1.10
0.85
9.0
7.5
2.92
2.96
%
0.15
453
4297
105
893
1.18
0.85
6.2
5.1
6.23
7.24
umol/l
0.35
93
754
23
160
1.43
0.85
3.9
3.3
1.06
1.20
e9/l
0.48
18
128
13
79
1.64
0.85
1.1
1.3
0.54
19.39
u/ml
0.91
13
74
221
1986
1.13
0.84
2.5
2.5
57.37
60.88
u/l
0.46
207
1847
12
72
1.66
0.82
1.2
1.3
153.44
195.12
pmol/l
0.46
12
72
192
2098
0.89
0.81
3.1
2.7
—
—
—
0
0
36
273
1.31
0.81
12.3
15.2
—
—
—
0
0
56
450
1.24
0.81
4.8
4.4
—
—
—
0
0
94
796
1.18
0.81
1.5
1.4
—
—
—
0
0
6
32
1.86
0.81
1.3
1.5
—
—
—
0
0
24
172
1.39
0.77
10.8
8.1
—
—
—
0
0
518
4883
1.09
0.77
9.7
7.8
0.19
0.19
e9/l
0.19
462
4290
450
4216
1.09
0.77
6.1
5.2
6.18
6.22
mmol/l
0.10
413
3903
73
608
1.20
0.76
1.2
1.4
—
—
—
0
0
17
114
1.48
0.76
4.9
3.8
21.35
24.32
umol/l
0.97
17
114
16
106
1.50
0.76
1.1
1.4
—
—
—
0
0
5
23
2.16
0.76
1.2
1.6
—
—
—
0
0
28
207
1.35
0.75
5.0
7.1
—
—
—
0
0
504
4749
1.09
0.75
9.4
7.4
0.04
0.04
e9/l
0.19
443
4092
522
4927
1.09
0.75
4.0
3.6
31.49
34.96
u/l
0.85
501
4713
9
54
1.65
0.74
1.0
1.2
—
—
—
0
0
10
59
1.68
0.73
8.8
7.1
—
—
—
0
0
347
3219
1.10
0.73
3.2
2.7
—
—
—
0
0
450
4225
1.09
0.72
2.8
2.6
—
—
—
0
0
503
4746
1.09
0.72
9.4
7.4
0.54
0.54
e9/l
0.00
443
4088
7
39
1.78
0.72
1.0
1.1
—
—
—
0
0
7
40
1.74
0.70
1.7
1.1
—
—
—
0
0
5
26
1.91
0.70
1.6
1.3
1.51
1.51
g/l
—
5
26
213
2291
0.90
0.69
2.1
2.1
—
—
—
0
0
20
142
1.40
0.69
1.8
2.0
135.96
139.96
ng/l
0.08
20
130
61
507
1.20
0.67
1.1
1.1
4.60
3.41
u/ml
0.21
45
355
21
280
0.74
0.67
1.1
1.1
—
—
—
0
0
7
43
1.61
0.66
2.7
4.4
20.05
21.32
ug/l
—
7
43
12
77
1.55
0.66
1.1
1.1
256.17
287.58
mg/l
1.03
12
72
867
8393
1.10
0.65
14.8
12.6
334.16
334.30
g/l
0.17
859
8306
10
152
0.65
0.64
2.5
3.0
30.74
25.06
mg/l
—
5
98
11
70
1.56
0.63
1.6
1.7
31.91
32.54
pg
0.15
11
70
92
798
1.15
0.62
3.9
3.6
1.52
1.77
ug/l
0.55
85
732
8
49
1.62
0.61
1.4
1.6
4.46
7.02
u/l
—
8
40
78
670
1.16
0.61
2.3
2.4
26.71
105.10
u/l
0.56
70
562
5
30
1.65
0.60
5.4
3.0
—
—
—
0
0
23
172
1.33
0.60
1.1
1.2
0.36
2.87
u/ml
2.30
17
104
129
1149
1.13
0.60
1.4
1.9
—
—
—
0
0
180
1634
1.11
0.60
1.7
1.6
1.33
1.30
mmol/l
0.27
163
1467
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
12
172
0.69
0.59
2.5
1.9
—
—
—
0
0
19
139
1.36
0.57
1.2
1.3
2.11
3.85
u/ml
—
9
72
128
1145
1.12
0.56
1.4
1.9
—
—
—
0
0
117
1041
1.13
0.56
1.8
1.5
—
—
—
0
0
123
1098
1.12
0.56
1.1
1.2
10.08
8.76
u/ml
0.06
36
393
157
1421
1.11
0.56
4.5
4.1
—
—
—
0
0
32
254
1.25
0.56
1.3
1.2
—
—
—
0
0
661
6349
1.07
0.55
3.2
2.9
5.52
5.53
mmol/l
0.08
605
5879
12
81
1.47
0.54
1.3
1.4
11.43
9.58
umol/l
0.22
12
81
6
38
1.57
0.54
2.0
2.1
—
—
—
0
0
13
91
1.42
0.50
1.0
1.0
—
—
—
0
0
126
1136
1.11
0.49
1.4
1.9
—
—
—
0
0
33
268
1.22
0.49
3.8
3.9
5.94
7.92
umol/l
0.86
26
220
10
142
0.69
0.48
1.3
1.5
—
—
—
0
0
18
135
1.32
0.48
1.7
1.3
—
—
—
0
0
7
47
1.48
0.47
1.1
1.9
—
—
—
0
0
52
444
1.17
0.46
4.2
3.1
—
—
—
0
0
24
189
1.26
0.46
3.8
3.6
3.42
3.56
e9/l
0.15
24
189
110
989
1.11
0.46
2.3
2.3
344.59
372.78
nmol/l
0.96
98
932
10
140
0.70
0.45
1.4
1.5
6.11
6.28
g/l
—
10
113
10
140
0.70
0.45
1.4
1.5
2.42
2.44
g/l
—
10
113
10
140
0.70
0.45
1.4
1.5
0.31
0.37
g/l
—
10
112
94
839
1.12
0.45
8.2
6.5
10.17
9.79
kpa
1.47
86
812
24
190
1.26
0.45
4.2
4.0
50.79
52.90
%
0.45
24
190
7
50
1.39
0.44
4.4
3.8
154.29
146.84
ug/l
—
7
50
13
94
1.37
0.43
3.1
3.4
641.35
190.62
u/ml
—
6
26
94
842
1.11
0.43
1.4
1.4
328.83
321.63
u/ml
0.02
89
783
184
1943
0.92
0.43
4.3
3.2
0.00
0.00
estimate
1.08
60
705
294
2770
1.07
0.42
2.3
2.0
—
—
—
0
0
10
69
1.44
0.42
2.2
1.7
—
—
—
0
0
8
56
1.42
0.42
1.5
1.5
—
—
—
0
0
8
57
1.39
0.41
2.6
2.7
637.00
1013.49
u/ml
—
8
57
40
338
1.18
0.41
1.6
1.6
1.06
1.15
g/l
1.21
40
324
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
3.9
—
4.30
—
0
16
5
33
1.50
0.41
1.0
1.2
—
—
—
0
0
5
33
1.50
0.41
1.0
1.2
—
—
—
0
0
5
33
1.50
0.41
1.2
1.3
—
—
—
0
0
5
33
1.50
0.41
1.0
1.2
—
—
—
0
0
117
1065
1.10
0.40
1.4
1.9
—
—
—
0
0
39
330
1.18
0.40
1.6
1.6
0.20
0.21
g/l
0.73
39
317
12
87
1.37
0.40
6.8
3.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
10
70
1.42
0.40
1.0
1.4
—
—
nmol/l
—
0
0
7
103
0.67
0.39
6.0
4.3
2.71
1.10
%
—
7
94
18
140
1.28
0.39
1.1
1.1
—
—
—
0
0
60
667
0.88
0.39
5.2
3.4
—
—
—
0
0
11
79
1.38
0.38
1.6
1.9
3.81
4.81
mmol/24h
0.57
11
72
187
1741
1.08
0.38
2.6
2.5
29.47
28.71
ng/l
0.02
103
756
30
250
1.19
0.37
1.3
1.2
—
—
—
0
0
8
114
0.69
0.37
1.3
2.3
293.75
294.43
mosm/kgh2o
—
8
89
14
106
1.31
0.37
5.9
3.3
—
—
—
0
0
9
69
1.29
0.37
5.3
1.2
20.14
11.67
u/l
—
9
63
18
142
1.26
0.36
3.7
2.6
—
—
—
0
0
63
559
1.12
0.36
1.3
1.4
—
—
—
0
0
174
1623
1.07
0.35
4.1
3.0
7.01
7.85
e6/l
0.28
149
1446
6
43
1.38
0.34
1.0
1.0
—
4.60
iu/ml
—
0
5
74
805
0.90
0.34
1.2
1.3
—
—
—
0
0
28
234
1.19
0.34
2.4
2.2
—
—
—
0
0
22
262
0.83
0.34
3.2
2.4
—
—
—
0
0
56
495
1.13
0.34
1.4
1.4
—
—
—
0
0
32
273
1.16
0.32
1.0
1.1
0.34
0.57
u/ml
0.29
15
98
20
163
1.22
0.31
1.2
1.3
2.96
7.99
u/ml
0.78
15
85
20
163
1.22
0.31
1.3
1.5
30.88
13.84
u/l
0.89
15
141
7
51
1.36
0.31
1.1
1.2
—
—
—
0
0
18
146
1.22
0.30
4.2
3.5
34.39
36.64
%
0.35
18
146
13
101
1.28
0.29
1.4
1.3
—
—
—
0
0
17
204
0.82
0.29
1.9
1.8
2860.74
6.14
iu/l
—
7
72
18
147
1.21
0.28
1.1
1.1
—
—
—
0
0
111
1030
1.07
0.27
3.0
3.3
453.48
861.43
ng/l
0.72
61
572
165
1715
0.94
0.27
1.8
1.8
—
—
—
0
0
239
2273
1.05
0.27
10.9
6.2
1.13
1.10
inr
0.29
60
724
13
159
0.81
0.27
4.9
3.6
—
—
—
0
0
146
1370
1.06
0.26
1.7
1.6
—
—
—
0
0
10
76
1.30
0.26
2.0
2.5
44060.00
41002.63
ug/l
—
10
76
11
85
1.28
0.26
1.0
1.4
—
—
—
0
0
10
126
0.78
0.26
2.4
2.8
—
—
—
0
0
13
158
0.81
0.25
9.5
5.8
1.03
1.97
mmol/l
—
8
90
13
158
0.81
0.25
9.5
5.8
4.98
4.97
kpa
0.05
13
158
9
72
1.24
0.25
1.4
1.6
—
—
—
0
0
12
95
1.25
0.24
17.4
11.1
11.30
12.16
%
0.26
12
95
18
150
1.19
0.24
1.0
1.1
—
—
—
0
0
25
215
1.15
0.24
7.6
9.7
24.55
24.05
mmol/l
0.36
25
202
90
949
0.93
0.23
2.9
2.2
13389.61
6577.79
u/l
0.66
21
285
16
132
1.20
0.23
3.1
3.6
190.00
245.98
e6/l
0.57
11
92
389
3754
1.04
0.23
5.2
4.3
0.00
0.00
estimate
0.50
63
730
84
778
1.07
0.23
1.7
2.3
—
—
—
0
0
11
87
1.25
0.22
1.5
1.8
—
—
—
0
0
42
457
0.91
0.22
1.0
1.1
—
—
—
0
0
7
93
0.74
0.22
1.3
1.1
—
—
—
0
0
16
133
1.19
0.22
9.7
4.6
1.16
1.44
mmol/l
1.52
16
128
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
3.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.1
—
0.44
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.20
0.0
1.0
—
—
—
0
0
389
3763
1.03
0.20
3.6
3.1
0.00
0.00
estimate
0.50
64
731
56
513
1.08
0.20
1.1
1.2
0.67
1.48
u/ml
1.60
43
326
6
48
1.24
0.20
1.0
1.0
—
20.11
—
0
13
6
48
1.24
0.20
1.3
1.2
—
0.20
—
0
12
57
524
1.08
0.19
1.1
1.2
14.05
9.37
u/ml
0.70
43
360
6
50
1.19
0.19
1.7
1.0
1748.92
1397.60
miu/ml
—
6
50
12
98
1.21
0.19
3.3
1.7
13.44
13.09
%
0.48
12
98
56
515
1.08
0.19
1.7
2.0
4.04
4.70
e9/l
0.65
51
463
10
80
1.24
0.19
1.5
1.3
0.10
2.51
u/ml
—
10
80
617
6187
0.97
0.19
3.8
3.4
2.64
2.73
mmol/l
1.07
575
5845
122
1154
1.05
0.18
1.2
1.2
39.19
22.56
iu/ml
0.27
34
316
47
430
1.08
0.18
1.2
1.3
260.84
257.34
miu/ml
0.02
19
198
7
57
1.22
0.18
1.1
1.1
152.86
243.75
iu/ml
—
7
57
7
57
1.22
0.18
1.1
1.2
—
—
—
0
0
10
81
1.22
0.17
1.6
1.8
—
—
—
0
0
119
1128
1.05
0.17
1.4
1.8
—
—
—
0
0
203
1949
1.04
0.16
1.8
1.7
—
—
—
0
0
8
69
1.15
0.16
1.5
1.6
—
—
—
0
0
17
147
1.15
0.16
4.7
5.9
—
—
—
0
0
8
71
1.12
0.16
1.0
1.2
—
—
—
0
0
8
72
1.10
0.15
1.5
1.1
—
—
—
0
0
6
79
0.75
0.15
1.2
1.4
—
—
—
0
0
12
101
1.18
0.15
1.3
1.1
—
—
—
0
0
26
234
1.10
0.14
1.0
1.1
—
—
—
0
0
14
158
0.88
0.14
9.6
5.6
9.78
9.39
kpa
0.23
14
158
611
6109
0.98
0.14
3.5
3.2
1.44
1.43
mmol/l
0.31
565
5788
26
235
1.10
0.13
1.0
1.1
—
—
—
0
0
31
283
1.09
0.13
2.7
2.1
25.10
38.68
u/ml
0.64
31
272
388
3779
1.02
0.13
3.7
3.1
0.00
0.00
estimate
-0.00
62
703
163
1568
1.03
0.13
4.3
3.0
620.85
608.09
mosm/kgh2o
0.25
135
1360
559
5472
1.02
0.12
4.0
3.8
36.86
37.29
mmol/mol
0.50
523
5180
57
592
0.95
0.11
1.8
1.8
—
—
—
0
0
39
410
0.94
0.11
7.5
4.6
1.24
1.23
mmol/l
0.48
33
365
13
114
1.13
0.10
5.5
4.8
—
—
—
0
0
25
229
1.08
0.10
1.0
1.1
—
—
—
0
0
20
181
1.09
0.10
1.3
1.4
274.11
336.08
ug/g
—
9
88
26
239
1.08
0.10
1.8
1.7
—
—
—
0
0
5
45
1.10
0.09
1.4
1.2
189.60
472.77
u/l
—
5
39
51
528
0.95
0.09
1.3
1.3
—
—
—
0
0
59
560
1.04
0.09
4.5
4.6
0.52
0.51
%
0.01
21
191
6
54
1.10
0.09
1.8
4.0
18.33
524.81
u/ml
—
6
49
42
396
1.05
0.08
1.5
1.5
—
—
—
0
0
20
183
1.08
0.08
16.8
5.3
—
—
—
0
0
61
583
1.04
0.07
1.2
1.2
2.80
4.02
u/ml
0.39
41
376
62
594
1.03
0.07
4.7
5.1
0.78
0.69
%
0.18
23
212
25
233
1.06
0.07
3.2
2.8
—
—
—
0
0
220
2148
1.02
0.06
1.5
1.7
—
—
—
0
0
10
110
0.90
0.06
1.1
1.3
—
—
—
0
0
22
231
0.94
0.06
1.4
1.1
—
—
—
0
0
37
351
1.04
0.06
1.1
1.1
5.39
4.97
u/ml
0.06
26
224
57
547
1.03
0.06
1.5
2.3
—
—
—
0
0
17
157
1.07
0.05
4.6
4.6
422.00
391.11
umol/l
0.50
17
143
10
90
1.10
0.04
1.2
1.6
—
—
—
0
0
58
560
1.03
0.04
4.9
5.2
0.11
0.09
%
0.07
19
176
47
478
0.97
0.04
1.1
1.2
—
—
—
0
0
11
118
0.92
0.04
15.2
6.5
—
—
—
0
0
629
6201
1.01
0.03
3.7
3.3
4.48
4.52
mmol/l
0.37
587
5902
21
198
1.05
0.03
1.4
1.5
—
—
—
0
0
272
2710
0.99
0.03
1.5
1.6
—
—
—
0
0
17
159
1.06
0.03
1.1
1.8
—
—
—
0
0
182
1816
0.99
0.03
3.2
2.9
1.02
1.02
kg/l
1.87
21
255
26
248
1.04
0.03
1.4
1.5
—
—
—
0
0
94
918
1.01
0.02
1.5
1.9
—
—
—
0
0
28
268
1.03
0.02
1.7
1.6
—
—
—
0
0
439
4328
1.01
0.02
11.2
9.0
0.00
0.00
e9/l
0.34
353
3449
83
831
0.99
0.02
1.2
1.3
116.07
136.00
iu/ml
0.23
27
286
10
92
1.08
0.02
2.5
1.7
—
—
—
0
0
19
181
1.04
0.01
1.2
2.0
—
—
—
0
0
56
547
1.01
0.01
4.8
5.2
0.00
0.08
%
1.15
17
160
84
838
0.99
0.01
1.8
2.0
—
—
—
0
0
77
756
1.01
0.00
1.5
1.4
—
—
—
0
0
26
255
1.01
0.00
3.0
2.6
10.80
17.29
e6/l
0.29
20
195
29
290
0.99
0.00
4.7
4.0
4.60
23.37
ug/l
0.60
19
216
30
292
1.02
0.00
1.5
1.6
—
—
—
0
0
26
256
1.00
0.00
1.5
1.5
—
—
—
0
0
18
179
0.99
0.00
6.2
8.4
—
—
—
0
0
35
347
1.00
0.00
1.4
1.2
—
—
—
0
0
594
5879
1.00
0.00
3.4
3.0
1.15
1.20
mmol/l
1.08
551
5563
32
314
1.01
0.00
1.0
1.1
20.19
9.18
u/ml
0.92
18
181
19
189
0.99
0.00
9.4
4.6
—
—
—
0
0
13
128
1.00
0.00
1.1
1.1
—
—
—
0
0
13
131
0.98
0.00
1.0
1.1
—
—
—
0
0
25
247
1.00
0.00
1.4
1.4
—
—
—
0
0
21
205
1.01
0.00
1.0
1.2
232.44
213.38
iu/ml
—
9
65
11
110
0.99
0.00
2.5
3.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
59
1.01
-0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
217.25
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
69
0.86
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
10.5
—
—
—
0
0
8
83
0.95
-0.00
1.9
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.89
-0.00
1.3
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
12.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
93
0.96
-0.00
6.6
5.3
2.77
1.30
ug/l
—
9
93
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
63
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
19.30
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_SCISS_BITE and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_SCISS_BITE.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: K11_SCISS_BITE – Scissor bite

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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