Other and unspecified trigeminal disorders

G6_TRIOTHUNS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G50.8, G50.9
  • Hospital discharge: ICD-9 350[8-9]
  • Hospital discharge: ICD-8 35601
  • Cause of death: ICD-10 G50.8, G50.9
  • Cause of death: ICD-9 350[8-9]
  • Cause of death: ICD-8 35601

2 out of 7 registries used, show all original rules.

577

4. Check minimum number of events

None

577

5. Include endpoints

None

577

6. Filter based on genotype QC (FinnGen only)

577

Control definitions (FinnGen only)

Control exclude
G6_NERPLEX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3637 2471 1148
Only index persons 3305 2291 1014
Unadjusted period prevalence (%)
Whole population 0.06 0.07 0.03
Only index persons 0.07 0.08 0.04
Median age at first event (years)
Whole population 53.77 53.33 54.63
Only index persons 52.31 52.25 52.47

-FinnGen-

Key figures

All Female Male
Number of individuals 577 416 161
Unadjusted period prevalence (%) 0.12 0.14 0.07
Median age at first event (years) 53.80 52.54 57.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
525
Matched controls
5250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
+∞
323.0
283
*
G50.9
ICD-10 Finland
Disorder of trigeminal nerve, unspecified
+∞
294.4
254
*
G50.0
ICD-10 Finland
Trigeminal neuralgia
399.6
193.0
183
7
G50.1
ICD-10 Finland
Atypical facial pain
254.6
176.1
172
10
N03AF01
ATC
carbamazepine; oral, rectal
27.3
127.6
181
99
N03AX12
ATC
gabapentin; oral
12.3
117.7
246
352
N03AX16
ATC
pregabalin; oral
9.5
113.0
295
622
N06AX21
ATC
duloxetine; oral
7.6
55.3
143
246
R51.81
ICD-10 Finland
Facial pain NOS
25.2
55.1
78
36
119
Kela drug reimbursment
Trigeminal neuralgia or glossofaryngeusneuralgia
+∞
54.1
51
*
N02AX02
ATC
tramadol; systemic, rectal
4.1
51.0
314
1393
SAA04
NOMESCO Finland
Special inverstigation of mouth
10.6
49.9
102
117
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
14.5
49.5
86
70
K07.60
ICD-10 Finland
Snapping jaw
10.0
48.3
102
124
G56.0
ICD-10 Finland
Carpal tunnel syndrome
16.3
46.1
76
54
N03AF02
ATC
oxcarbazepine; oral
14.1
44.6
78
64
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
7.3
42.5
110
184
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.6
42.3
299
1404
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.7
41.2
261
1115
WZB00
NOMESCO Finland
Telephone receipt or other advice
3.8
40.9
240
962
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
8.7
40.0
91
124
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
5.5
39.4
129
291
N03AE01
ATC
clonazepam; systemic
7.9
39.2
95
143
F45.8
ICD-10 Finland
Other somatoform disorders
7.1
38.9
102
172
N06AA09
ATC
amitriptyline; systemic
6.0
38.9
118
242
M03BX01
ATC
baclofen; systemic
22.2
38.4
56
28
R52.2
ICD-10 Finland
Other chronic pain
11.7
37.4
71
69
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
8.8
36.6
82
108
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.6
35.9
99
178
N03AX09
ATC
lamotrigine; oral
9.3
35.7
77
95
R51.80
ICD-10 Finland
Headache
4.4
33.1
139
401
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
25.8
32.4
45
19
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
4.6
31.2
121
321
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
21.3
30.6
45
23
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
15.3
29.5
49
35
M79.1
ICD-10 Finland
Myalgia
4.1
28.7
126
374
SAA03
NOMESCO Finland
Extended examination of mouth
2.9
28.7
268
1392
N06AX16
ATC
venlafaxine; oral
4.0
27.3
125
384
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.8
27.1
98
240
ACC51
NOMESCO Finland
Release of median nerve
79.5
27.1
30
*
N02AA05
ATC
oxycodone; systemic
4.1
26.0
111
319
A02BC02
ATC
pantoprazole; systemic
2.8
25.7
381
2550
EB1AA
NOMESCO Finland
Tooth X-ray examination
2.7
25.4
339
2122
G51.0
ICD-10 Finland
Bell palsy
261.9
24.9
25
*
H02AB06
ATC
prednisolone; systemic
2.6
24.8
285
1628
A02BC05
ATC
esomeprazole; systemic
2.6
24.5
268
1486
M01AE03
ATC
ketoprofen; systemic, rectal
2.6
23.7
245
1305
SBB10
NOMESCO Finland
Teeth copy
5.8
23.4
69
133
R52.1
ICD-10 Finland
Chronic intractable pain
38.2
23.2
29
8
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
239.9
22.8
23
*
EB1AD
NOMESCO Finland
Cone beam CT of teeth and jaws (one quarter)
47.3
22.6
27
6
M03BX02
ATC
tizanidine; oral
2.6
22.5
363
2445
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
30.6
22.1
29
10
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
13.1
21.7
38
31
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
21.6
189
904
N03
ICPC
Pain face
29.5
21.1
28
10
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
14.9
21.1
35
25
K08.80
ICD-10 Finland
Toothache NOS
4.4
21.1
81
208
N92
ICPC
Trigeminal neuralgia
218.2
20.7
21
*
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
11.0
19.5
37
36
M01AE02
ATC
naproxen; oral, rectal
2.3
19.3
334
2241
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.6
19.3
94
298
A02BC03
ATC
lansoprazole; oral
2.5
19.2
191
965
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
19.2
251
1463
AAH30
NOMESCO Finland
Thermal destruction of cranial nerve
+∞
18.9
18
*
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
18.8
160
741
R52.9
ICD-10 Finland
Pain, unspecified
4.2
18.6
74
196
N02BE01
ATC
paracetamol; systemic, rectal
3.1
18.4
466
3779
M01AB05
ATC
diclofenac; systemic, rectal
2.4
18.1
375
2701
R20.2
ICD-10 Finland
Paraesthesia of skin
4.7
17.5
61
142
M54.5
ICD-10 Finland
Low back pain
2.4
17.4
197
1053
SAA01
NOMESCO Finland
Simple examination of mouth
2.4
17.4
391
2900
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
17.3
221
1256
M79.6
ICD-10 Finland
Pain in limb
2.3
17.2
209
1157
J01FF01
ATC
clindamycin; systemic
2.5
17.0
169
842
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.2
17.0
280
1789
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
16.9
269
1689
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.3
16.9
93
322
Z01.8
ICD-10 Finland
Other specified special examinations
2.6
16.8
145
672
N03AX11
ATC
topiramate; oral
8.7
16.8
36
44
J01DB01
ATC
cefalexin; oral
2.6
16.8
444
3543
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.5
16.7
85
278
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
5.3
16.5
51
104
WX110
NOMESCO Finland
Local anesthesy
2.3
16.3
379
2804
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.6
15.9
140
652
M01AH05
ATC
etoricoxib; oral
2.2
15.9
325
2258
35601
ICD-8 Finland
Other diseases of cranial nerves, Nervi trigemini
+∞
15.7
15
*
N06AA10
ATC
nortriptyline; systemic
8.4
15.5
34
43
M79.0
ICD-10 Finland
Rheumatism, unspecified
6.4
15.5
41
69
SAA02
NOMESCO Finland
Basic examination of mouth
2.2
15.4
354
2568
AA1AD
NOMESCO Finland
CT of head and brain
2.5
15.3
141
673
R01AD08
ATC
fluticasone; nasal
2.3
15.2
182
991
R20.1
ICD-10 Finland
Hypoaesthesia of skin
46.4
15.1
18
*
M25.5
ICD-10 Finland
Pain in joint
2.3
15.1
173
921
M54.4
ICD-10 Finland
Lumbago with sciatica
2.8
14.9
106
435
P01AB01
ATC
metronidazole; oral, rectal
2.1
14.8
236
1452
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
14.8
210
1228
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
19.1
14.8
22
12
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
14.8
174
935
K07.61
ICD-10 Finland
Cracking jaw joint
11.8
14.4
26
23
R01AD09
ATC
mometasone; nasal
2.1
14.4
258
1665
H02AB04
ATC
methylprednisolone; systemic
2.7
14.0
104
436
G44.2
ICD-10 Finland
Tension-type headache
2.8
14.0
97
388
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.6
14.0
66
203
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.6
13.9
114
508
SGC00
NOMESCO Finland
Local medication of root channels of tooth
3.2
13.5
76
266
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.3
13.5
156
827
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
8.5
13.5
29
36
N06AX11
ATC
mirtazapine; oral
2.1
13.5
192
1115
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
21.8
13.4
19
9
N05BA04
ATC
oxazepam; oral
2.2
13.3
156
831
J01MA12
ATC
levofloxacin; systemic
2.6
13.2
108
478
A06AC01
ATC
ispaghula (psylla seeds); oral
2.3
13.2
149
779
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
13.1
241
1553
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
13.1
278
1894
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
6.0
13.1
36
64
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
4.4
13.1
48
118
K04.1
ICD-10 Finland
Necrosis of pulp
3.2
13.0
73
255
R20.3
ICD-10 Finland
Hyperaesthesia
51.3
12.9
15
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.7
12.8
97
410
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
12.7
154
829
R06.0
ICD-10 Finland
Dyspnoea
2.3
12.7
141
728
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
5.2
12.6
39
80
H04.10
ICD-10 Finland
Dry eye syndrome
3.1
12.5
74
266
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
6.5
12.5
32
52
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.3
12.3
63
206
A02BC01
ATC
omeprazole; systemic
2.2
12.3
160
888
UDQ12
NOMESCO Finland
Flexible laryngoscopy
4.4
12.2
44
106
WZA90
NOMESCO Finland
Other doctors statement
2.2
12.1
138
722
N05AH04
ATC
quetiapine; oral
2.5
12.1
101
451
J01FA10
ATC
azithromycin; systemic
1.9
12.0
320
2344
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.6
11.9
54
161
R53
ICD-10 Finland
Malaise and fatigue
2.3
11.9
120
589
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.4
11.9
59
189
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
11.9
112
534
R01BA52
ATC
pseudoephedrine, combinations; oral
2.0
11.8
184
1098
K04.00
ICD-10 Finland
Hyperemia of pulp
4.9
11.8
38
82
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
11.7
133
689
S04.3
ICD-10 Finland
Injury of trigeminal nerve
+∞
11.5
11
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.0
11.4
69
253
UJF32
NOMESCO Finland
Coloscopy
2.1
11.4
147
807
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
11.3
147
809
SXC05
NOMESCO Finland
Other oral or dental procedure
3.5
11.3
53
162
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
11.2
60
204
J01AA02
ATC
doxycycline; systemic
2.1
11.1
419
3439
L03
ICPC
Low back symptom/complaint
2.1
11.0
138
749
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
10.9
75
300
R42
ICD-10 Finland
Dizziness and giddiness
2.2
10.9
128
675
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.5
10.8
94
428
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.8
10.8
73
287
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
10.7
184
1129
A01
ICPC
Pain general/multiple sites
3.5
10.7
50
153
K10.21
ICD-10 Finland
Osteoradionecrosis of jaw (acute)(chronic)(suppurative)
61.2
10.7
12
*
M53.0
ICD-10 Finland
Cervicocranial syndrome
3.0
10.7
64
232
N05CF01
ATC
zopiclone; oral
2.0
10.6
180
1100
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
10.6
128
683
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.5
10.6
49
149
M01AC06
ATC
meloxicam; systemic, rectal
1.9
10.5
198
1261
AAH60
NOMESCO Finland
Microvascular decompression of cranial nerve
+∞
10.4
10
*
UJF30
NOMESCO Finland
Ileoscopy through colon
2.9
10.4
65
244
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.3
10.4
24
34
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.1
10.3
40
104
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.5
10.2
47
142
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
10.2
58
205
J45.9
ICD-10 Finland
Asthma, unspecified
2.3
10.0
100
487
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
17.1
9.9
15
9
N05BA01
ATC
diazepam; systemic, rectal
2.4
9.9
88
405
G43.9
ICD-10 Finland
Migraine, unspecified
3.6
9.9
44
130
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
56.0
9.7
11
*
S06.0
ICD-10 Finland
Concussion
2.9
9.6
60
225
M54.2
ICD-10 Finland
Cervicalgia
3.5
9.6
45
138
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.7
9.6
67
270
A06AC51
ATC
ispaghula, combinations; systemic
3.7
9.6
41
117
N05CF02
ATC
zolpidem; oral
2.2
9.6
106
542
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.8
9.5
276
2009
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.3
9.5
48
156
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
9.5
231
1588
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
9.5
59
221
J01MA02
ATC
ciprofloxacin; systemic
1.9
9.5
197
1285
M01AX17
ATC
nimesulide; oral
2.0
9.4
136
776
RF211
NOMESCO Finland
NA
101.8
9.4
10
*
R20.0
ICD-10 Finland
Anaesthesia of skin
17.9
9.4
14
8
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.5
9.4
32
74
TAB00
NOMESCO Finland
Lumbar puncture
3.9
9.3
38
104
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.4
9.2
81
370
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.6
9.1
40
117
N07BC02
ATC
methadone; systemic
37.4
9.0
11
*
M19.9
ICD-10 Finland
Arthrosis, unspecified
5.4
9.0
26
50
Z01.9
ICD-10 Finland
Special examination, unspecified
3.6
9.0
40
118
M01AH02
ATC
rofecoxib; oral
2.4
9.0
78
354
M79.7
ICD-10 Finland
Fibromyalgia
5.0
9.0
28
59
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.4
9.0
43
135
M02AA07
ATC
piroxicam; topical
1.8
9.0
197
1303
WX002
NOMESCO Finland
Sedation and analgesia
2.1
8.9
111
593
N02AC04
ATC
dextropropoxyphene; oral
4.7
8.9
29
64
K07.13
ICD-10 Finland
Retrognaty, mandibular
8.2
8.9
19
24
A02BA02
ATC
ranitidine; systemic
2.1
8.9
113
612
A07AA02
ATC
nystatin; oral
3.2
8.8
45
148
A03FA02
ATC
cisapride; oral, rectal
3.0
8.8
51
183
C07AA05
ATC
propranolol; systemic
2.1
8.7
115
631
H57.1
ICD-10 Finland
Ocular pain
4.9
8.7
27
57
R03AC02
ATC
salbutamol; inhalant
1.7
8.6
272
2009
J01FA06
ATC
roxithromycin; oral
1.8
8.6
224
1560
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
8.6
44
145
R01AD12
ATC
fluticasone furoate; nasal
1.9
8.6
161
1007
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
9.2
8.6
17
19
A06AD11
ATC
lactulose; oral
2.4
8.6
77
354
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.9
8.5
51
187
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
13.0
8.4
14
11
M01AG02
ATC
tolfenamic acid; oral, rectal
2.1
8.4
98
512
R03BA01
ATC
beclometasone; inhalant
2.2
8.4
87
429
N03A
ATC
ANTIEPILEPTICS
+∞
8.4
8
*
3540A
ICD-9 Finland
Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome
+∞
8.4
8
*
G50
ICD-10 Finland
Disorders of trigeminal nerve
+∞
8.4
8
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.9
8.3
50
184
R50.9
ICD-10 Finland
Fever, unspecified
2.3
8.3
78
366
M01AB55
ATC
diclofenac, combinations; oral
3.0
8.3
47
166
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.9
8.2
146
892
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
8.1
52
199
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.6
8.1
61
255
K30
ICD-10 Finland
Functional dyspepsia
2.5
8.1
64
275
N02CC04
ATC
rizatriptan; oral
3.1
8.1
43
146
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.0
8.1
31
81
M50.3
ICD-10 Finland
Other cervical disc degeneration
6.5
8.1
20
32
W0A10
NOMESCO Finland
Mapping of psychosocial situation
22.4
8.0
11
5
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.9
8.0
25
53
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.5
8.0
36
108
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.5
7.9
27
63
M01AH01
ATC
celecoxib; oral (coxibs)
2.1
7.9
102
552
J01DA01
ATC
[U] cefalexin; systemic
1.7
7.9
320
2515
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
7.9
98
521
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.9
7.9
31
83
J01DA06
ATC
[U] cefuroxime; systemic
2.2
7.9
88
448
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.1
7.9
44
152
J05AB01
ATC
aciclovir; systemic
1.9
7.9
121
703
SPAT1263
SPAT
Sampling
1.7
7.9
216
1515
G56.2
ICD-10 Finland
Lesion of ulnar nerve
11.0
7.8
14
13
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.9
7.8
47
174
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.9
7.8
46
168
EB1MA
NOMESCO Finland
Cephalometry with X-ray
6.5
7.8
19
30
Z04.3
ICD-10 Finland
Examination and observation following other accident
6.5
7.8
19
30
WX290
NOMESCO Finland
Other blockade of nerve
1.7
7.8
219
1546
M48.0
ICD-10 Finland
Spinal stenosis
2.5
7.7
62
270
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
7.7
118
680
R03DC03
ATC
montelukast; oral
2.1
7.7
93
489
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
4.3
7.7
27
65
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
5.3
7.6
22
43
K07.58
ICD-10 Finland
Other abnormal function of teeth and jaws
18.7
7.6
11
6
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
2.3
7.6
71
332
R13
ICD-10 Finland
Dysphagia
3.1
7.6
41
141
H53.1
ICD-10 Finland
Subjective visual disturbances
3.0
7.6
43
151
ZXC10
NOMESCO Finland
Use of laser
4.8
7.6
24
52
H02AB07
ATC
prednisone; oral
2.2
7.6
84
425
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.0
7.6
29
76
K04.4
ICD-10 Finland
Acute apical periodontitis of pulpal origin
2.7
7.6
52
208
K14.60
ICD-10 Finland
Glossopyrosis
10.2
7.6
14
14
J31.0
ICD-10 Finland
Chronic rhinitis
2.8
7.6
47
175
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
7.5
145
909
UKC02
NOMESCO Finland
Cystoscopy
2.2
7.5
78
386
Z01.2
ICD-10 Finland
Dental examination
1.7
7.5
213
1503
J02AC01
ATC
fluconazole; systemic
1.7
7.5
224
1605
SPAT1104
SPAT
Monitoring of emergency patient
2.9
7.5
43
154
EGA00
NOMESCO Finland
Arthroscopy of mandibular joint
81.2
7.4
8
*
XX2XT
NOMESCO Finland
Other injection with other radiological guidance
81.2
7.4
8
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
7.4
104
582
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
13.6
7.4
12
9
L08
ICPC
Shoulder symptom/complaint
2.0
7.4
98
535
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
7.4
42
149
N05CD07
ATC
temazepam; oral
2.3
7.4
67
310
J05AB11
ATC
valaciclovir; oral
2.2
7.4
76
372
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
7.4
59
255
R06AE07
ATC
cetirizine; oral
1.7
7.3
232
1689
G51.8
ICD-10 Finland
Other disorders of facial nerve
+∞
7.3
7
*
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
16.0
7.3
11
7
Z50.1
ICD-10 Finland
Other physical therapy
3.6
7.2
31
90
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.6
7.2
292
2266
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
7.2
95
518
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.9
7.2
42
153
EEC05
NOMESCO Finland
Le Fort I osteotomy
20.3
7.2
10
5
SGB30
NOMESCO Finland
Other demanding filling of root channel of tooth
2.3
7.1
66
309
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.8
7.1
136
849
H03AA01
ATC
levothyroxine sodium; systemic
1.8
7.0
132
818
H92.0
ICD-10 Finland
Otalgia
3.1
7.0
37
126
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
4.2
7.0
25
62
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.5
7.0
52
219
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.1
7.0
36
121
N06AB04
ATC
citalopram; systemic
1.9
6.9
117
698
C10AA05
ATC
atorvastatin; oral
1.7
6.9
172
1162
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.5
6.9
23
53
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
14.0
6.9
11
8
L01
ICPC
Neck symptom/complaint
2.2
6.9
73
363
G44.8
ICD-10 Finland
Other specified headache syndromes
8.4
6.9
14
17
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.3
6.8
32
100
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
11.1
6.8
12
11
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
11.1
6.8
12
11
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
6.8
116
693
K04.0
ICD-10 Finland
Pulpitis
2.3
6.8
62
289
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.2
6.8
24
59
M01AE01
ATC
ibuprofen; systemic, rectal
2.0
6.8
461
4120
R06.5
ICD-10 Finland
Mouth breathing
2.7
6.8
44
171
T88.8
ICD-10 Finland
Other specified complications of surgical and medical care, not elsewhere classified
40.6
6.8
8
*
R07.3
ICD-10 Finland
Other chest pain
2.4
6.8
54
236
R51
ICD-10 Finland
Headache
3.1
6.7
35
118
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.2
6.7
66
319
K04.09
ICD-10 Finland
Pulpit UNS
3.6
6.7
28
80
EG1CG
NOMESCO Finland
Extensive MRI examination of mandipular joint with high intensity magnet
22.8
6.7
9
*
EB1WA
NOMESCO Finland
NA
22.8
6.7
9
*
L28
ICPC
Limited function/disability (L)
2.1
6.7
76
390
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.0
6.7
38
135
N06AA12
ATC
doxepin; systemic
3.0
6.7
38
135
SJC10
NOMESCO Finland
Orthodontic bandage in one tooth
8.0
6.6
14
18
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
4.9
6.6
20
42
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
8.9
6.6
13
15
M03BC51
ATC
orphenadrine, combinations; systemic
1.7
6.6
154
1019
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.9
6.6
38
137
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
6.6
83
445
R11
ICD-10 Finland
Nausea and vomiting
2.6
6.6
47
194
EBB15
NOMESCO Finland
Insertion of dental implant abutment
10.2
6.6
12
12
H16.0
ICD-10 Finland
Corneal ulcer
3.3
6.5
31
98
D20
ICPC
Mouth/tongue/lip symptom/complaint
3.3
6.5
31
98
C08DA01
ATC
verapamil; systemic
3.2
6.5
32
104
K59.0
ICD-10 Finland
Constipation
3.0
6.5
37
131
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
6.5
61
286
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
6.5
84
455
SJD10
NOMESCO Finland
Attachment of arrow to fixed orthodontisk device
7.5
6.4
14
19
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.5
6.4
28
83
A02BC04
ATC
rabeprazole; oral
2.4
6.4
53
233
L02
ICPC
Back symptom/complaint
2.4
6.4
51
223
C05AA08
ATC
fluocortolone; rectal, topical
2.1
6.3
74
385
M54
ICD-10 Finland
Dorsalgia
2.2
6.3
65
318
EBB10
NOMESCO Finland
Insertion of dental implant
6.1
6.3
16
27
SJD40
NOMESCO Finland
Fixation of ready made palatinal or lingual arrow
11.2
6.3
11
10
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
11.2
6.3
11
10
G47.3
ICD-10 Finland
Sleep apnoea
1.9
6.3
94
537
SGA04
NOMESCO Finland
Very demanding opening and dilatation of root canal of tooth
2.2
6.3
63
307
H53.2
ICD-10 Finland
Diplopia
4.9
6.3
19
40
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
6.3
69
349
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.8
6.3
37
136
3501A
ICD-9 Finland
Trigeminal nerve disorders, Trigeminal neuralgia
+∞
6.3
6
*
G51.9
ICD-10 Finland
Disorder of facial nerve, unspecified
+∞
6.3
6
*
35199
ICD-8 Finland
Trigeminal neuralgia
+∞
6.3
6
*
3509X
ICD-9 Finland
Trigeminal nerve disorders, Trigeminal nerve disorder, unspecified
+∞
6.3
6
*
T78.4
ICD-10 Finland
Allergy, unspecified
3.3
6.3
30
96
N83.1
ICD-10 Finland
Corpus luteum cyst
7.2
6.3
14
20
EDA10
NOMESCO Finland
Biopsy of mandible
27.0
6.2
8
*
EBA12
NOMESCO Finland
Complicated surgical removal of tooth
4.6
6.2
20
45
L07
ICPC
Jaw symptom/complaint
6.4
6.2
15
24
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.7
6.2
25
70
SPAT1153
SPAT
Removal of sutures
1.7
6.2
153
1026
G44.0
ICD-10 Finland
Cluster headache syndrome
7.8
6.2
13
17
L11
ICPC
Wrist symptom/complaint
2.7
6.1
40
156
N05BA12
ATC
alprazolam; oral
2.2
6.1
61
294
N06AB10
ATC
escitalopram; oral
1.8
6.1
107
644
SPAT1260
SPAT
Consultation of another employee
1.9
6.1
89
505
K60.1
ICD-10 Finland
Chronic anal fissure
5.0
6.1
18
37
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
6.1
133
863
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.8
6.1
36
133
SJD20
NOMESCO Finland
Attachment of modifiable arrow of fixed orthodontisk device
6.8
6.1
14
21
G35
ICD-10 Finland
Multiple sclerosis
6.8
6.1
14
21
M65.3
ICD-10 Finland
Trigger finger
4.1
6.1
22
56
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.1
6.1
22
56
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.6
6.1
202
1467
K07.68
ICD-10 Finland
Other disorders of the jaw joint
10.2
6.1
11
11
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
10.2
6.1
11
11
SJD00
NOMESCO Finland
Removal or reattacment of arrow in fixed orthodontisk device
6.1
6.0
15
25
F61.0
ICD-10 Finland
Mixed personality disorders
5.7
6.0
16
29
J01AA07
ATC
tetracycline; systemic
1.9
6.0
83
461

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
362
2346
2.46
23.61
5.9
5.7
1.9
1.9
e9/l
0.42
324
2062
364
2372
2.45
23.34
6.0
6.1
0.2
0.2
e9/l
0.51
327
2077
354
2280
2.43
23.28
5.9
5.7
0.5
0.6
e9/l
0.92
314
1968
355
2292
2.43
23.18
5.9
5.7
0.0
0.0
e9/l
0.12
313
1977
320
2002
2.34
22.07
5.9
5.2
1.2
1.2
mmol/l
0.11
293
1813
233
1300
2.33
20.68
2.6
2.1
133.4
233.1
u/l
1.20
221
1225
231
1292
2.31
20.31
4.4
3.4
—
—
—
0
0
137
607
2.65
20.04
1.4
1.3
646.7
482.7
titre
0.30
24
132
254
1495
2.25
19.59
5.7
5.7
—
—
—
0
0
459
3469
2.58
19.11
5.4
3.9
11.9
11.8
mm/h
0.03
427
3188
333
2202
2.21
19.03
6.2
6.0
1.2
1.2
mmol/l
0.08
273
1850
269
1635
2.21
19.01
4.4
3.3
31.8
33.3
ng/l
0.05
175
1082
371
2599
2.20
17.84
5.5
4.4
6.5
6.5
mmol/l
0.19
356
2430
100
401
2.81
17.62
2.9
2.2
348.9
364.7
nmol/l
0.29
89
375
329
2209
2.14
17.53
6.4
6.0
29.2
28.4
%
0.73
309
2057
347
2384
2.14
17.34
6.1
6.1
9.5
10.9
umol/l
3.30
323
2254
320
2138
2.12
17.13
6.3
5.9
3.0
2.7
%
1.41
300
1983
321
2148
2.11
17.11
6.7
6.1
8.6
8.5
%
0.22
303
2008
464
3595
2.48
17.07
8.4
7.1
73.8
77.8
u/l
1.79
436
3368
311
2067
2.09
16.75
6.2
5.9
0.7
0.7
%
0.38
289
1916
236
1417
2.13
16.64
3.0
2.4
51.3
56.6
u/l
1.68
215
1296
100
415
2.71
16.44
3.8
3.5
—
—
—
0
0
322
2191
2.06
16.01
6.0
5.7
56.0
57.0
%
0.93
299
2051
266
1705
2.04
15.42
8.0
7.3
1.1
1.2
inr
0.33
82
538
147
750
2.29
15.41
1.9
1.6
1161.7
1258.8
nmol/l
0.60
101
557
276
1799
2.02
15.21
2.0
1.9
96.0
96.4
pmol/l
0.04
137
867
181
1012
2.15
15.09
2.1
1.6
0.7
1.2
mg/l
4.04
130
773
421
3205
2.16
14.96
5.6
4.0
—
—
—
0
0
372
2709
2.05
14.85
8.3
9.2
3.8
4.0
e9/l
1.30
333
2359
291
1955
1.99
14.49
2.8
2.3
79.9
77.0
nmol/l
0.87
265
1770
136
698
2.24
13.91
3.0
3.3
0.8
0.8
mmol/l
0.12
127
657
128
658
2.21
12.96
1.3
1.2
—
—
—
0
0
283
1937
1.90
12.82
4.2
4.1
36.3
35.8
g/l
0.72
263
1811
159
918
2.01
11.74
1.9
1.6
42969148.4
25729884.6
pmol/l
0.15
128
754
78
337
2.52
11.67
3.1
3.1
9.7
10.4
g/l
1.06
71
314
396
3074
1.92
11.66
6.1
4.2
136.7
1003.1
e6/l
—
7
55
220
1435
1.86
11.18
2.4
2.2
—
—
—
0
0
190
1183
1.90
11.16
3.4
2.9
765.1
1067.8
ng/l
1.30
159
1000
459
3776
2.05
11.01
5.6
4.0
14.6
14.7
pmol/l
0.70
423
3454
143
819
1.99
10.69
1.4
1.3
24.0
30.8
iu/ml
0.41
38
274
176
1092
1.88
10.32
4.2
4.7
—
—
—
0
0
32
90
3.71
10.07
3.4
3.6
3.6
4.4
e9/l
1.06
32
90
97
492
2.17
9.99
2.4
1.5
—
—
—
0
0
165
1012
1.88
9.98
1.5
1.5
19.9
21.3
nmol/l
0.59
129
862
32
93
3.58
9.60
3.6
4.0
53.8
58.5
%
1.15
32
93
60
252
2.54
9.49
1.3
1.2
—
—
—
0
0
68
303
2.41
9.49
2.8
2.8
66.9
67.0
g/l
0.03
59
278
175
1109
1.83
9.47
2.5
2.1
2.8
3.0
mg/l
0.82
153
939
151
919
1.87
9.27
3.0
2.5
4.0
5.7
e6/l
1.74
132
817
171
1082
1.82
9.27
2.4
2.0
—
—
—
0
0
60
256
2.50
9.19
2.2
2.3
—
—
—
0
0
281
2056
1.71
9.14
3.1
2.6
105.2
109.0
ug/l
0.18
262
1890
42
150
2.94
9.06
2.5
1.6
431.1
313.7
mu/l
0.62
35
138
32
97
3.43
9.02
1.3
1.1
4.9
12.7
u/l
3.87
24
83
59
252
2.49
9.01
3.2
2.9
7.4
7.4
ph
—
8
33
105
571
2.03
8.95
2.2
2.3
141.7
119.7
ug/g
0.28
74
437
508
4447
2.19
8.76
6.5
4.8
1.8
2.2
mu/l
0.81
476
4090
540
4860
2.73
8.58
21.1
13.8
139.4
139.7
mmol/l
2.54
533
4725
132
790
1.87
8.46
1.4
1.2
11.4
11.2
u/ml
0.01
49
315
540
4873
2.69
8.29
21.0
13.9
3.9
3.9
mmol/l
0.62
533
4727
529
4740
2.39
8.06
20.2
12.3
18.7
22.7
mg/l
2.16
460
3655
182
1227
1.71
7.70
5.0
3.9
0.0
0.0
estimate
0.00
80
437
225
1606
1.66
7.65
3.1
3.4
2.4
2.4
mmol/l
0.14
193
1417
92
505
1.98
7.59
1.2
1.3
—
—
—
0
0
59
273
2.29
7.55
2.6
1.6
1.0
1.2
g/l
1.34
53
249
137
857
1.78
7.53
3.2
2.6
506.2
537.2
mosm/kgh2o
0.99
117
738
300
2321
1.61
7.25
5.6
4.7
0.0
0.0
estimate
0.00
80
443
283
2159
1.61
7.25
4.1
3.7
—
—
—
0
0
194
1351
1.66
7.17
3.8
3.6
7.4
7.4
ph
0.42
59
269
107
630
1.86
7.14
2.5
2.1
12.9
13.3
umol/l
0.22
98
581
296
2292
1.60
7.06
4.4
3.5
0.0
0.0
estimate
0.00
78
443
59
282
2.22
7.00
3.0
3.5
4.3
4.5
pmol/l
1.22
45
247
163
1093
1.68
6.93
4.2
3.9
—
—
—
0
0
300
2342
1.59
6.83
4.5
3.5
0.0
0.0
estimate
0.80
77
434
27
88
3.17
6.82
1.6
3.2
—
—
—
0
0
95
546
1.89
6.82
2.5
2.1
21.3
23.0
%
0.64
83
473
100
586
1.85
6.75
2.4
2.0
2.4
2.4
g/l
0.19
88
546
219
1595
1.60
6.65
4.4
3.5
66.8
85.0
e6/l
0.27
175
1113
262
1993
1.58
6.59
2.2
2.1
—
—
—
0
0
35
136
2.68
6.50
1.8
2.0
214.5
261.2
ug/l
0.29
30
125
43
185
2.43
6.49
3.7
2.7
—
—
—
0
0
188
1332
1.61
6.35
3.9
3.0
157.7
114.6
e6/l
0.11
157
1017
49
228
2.26
6.20
2.5
2.0
13.0
12.7
nmol/l
0.06
41
207
25
83
3.10
6.14
2.0
2.2
16.5
16.7
%
0.08
12
41
236
1777
1.56
6.08
3.8
3.3
—
—
—
0
0
92
549
1.80
5.83
3.8
4.3
1.0
1.0
mmol/l
0.41
84
504
14
32
4.46
5.79
2.4
3.0
—
—
—
0
0
74
413
1.91
5.79
6.1
3.8
—
—
—
0
0
488
4365
1.76
5.73
6.3
5.3
39.4
39.2
mmol/mol
0.13
446
4068
41
183
2.34
5.72
1.4
1.7
—
—
—
0
0
18
51
3.61
5.64
1.4
1.6
—
—
—
0
0
172
1223
1.58
5.61
3.8
2.9
0.3
0.4
e6/l
0.88
146
912
137
925
1.63
5.53
2.1
1.5
2.3
2.4
g/l
0.14
91
569
12
25
4.88
5.51
1.3
1.1
—
—
—
0
0
14
34
4.20
5.38
1.0
1.0
—
—
—
0
0
64
349
1.94
5.36
4.1
3.2
—
—
—
0
0
169
1208
1.56
5.35
3.8
2.8
—
—
—
0
0
25
91
2.83
5.27
2.5
3.5
1.9
2.9
mmol/l
0.86
15
60
86
522
1.76
5.14
17.1
21.0
1.3
1.2
inr
0.11
15
66
60
327
1.93
5.04
1.8
3.1
3.8
4.1
e9/l
0.39
46
256
73
425
1.82
5.01
1.8
2.9
1.8
1.8
%
0.18
65
380
150
1058
1.56
4.99
1.4
1.2
0.5
2.1
u/ml
2.44
48
287
18
56
3.29
4.93
1.9
1.9
92.3
88.9
%
3.02
18
56
42
203
2.15
4.88
1.3
1.2
—
—
—
0
0
19
62
3.13
4.83
1.9
1.8
1.8
1.6
mmol/l
0.32
19
62
61
341
1.88
4.76
2.5
2.5
6.7
7.4
ug/l
0.11
50
304
56
309
1.90
4.55
2.1
2.7
67.5
75.4
e9/l
1.04
47
234
16
49
3.33
4.50
1.2
1.3
—
—
nmol/l
—
0
0
158
1151
1.51
4.49
4.2
3.4
98.5
94.4
%
1.38
153
1118
16
50
3.26
4.36
1.3
1.3
—
—
—
0
0
61
351
1.83
4.35
3.3
4.9
0.2
0.1
%
0.15
17
98
154
1123
1.51
4.34
2.8
2.5
3240.6
8292.9
umol/l
0.87
130
984
173
1295
1.48
4.28
4.2
3.2
—
—
—
0
0
59
339
1.82
4.23
3.4
4.8
0.0
0.2
%
1.03
16
85
14
41
3.47
4.21
1.3
1.4
—
—
—
0
0
84
536
1.66
4.18
1.6
1.3
—
—
—
0
0
137
984
1.51
4.13
4.2
3.8
1.0
1.0
kg/l
0.03
23
124
21
80
2.69
4.11
1.2
1.2
—
—
—
0
0
15
47
3.25
4.08
1.6
2.1
33.7
31.9
pg
0.54
15
47
58
336
1.81
4.06
3.4
4.7
0.5
0.6
%
0.13
16
77
259
2108
1.41
4.04
11.0
9.1
0.0
0.0
e9/l
0.73
213
1743
185
1418
1.45
4.01
4.0
2.8
—
—
—
0
0
26
112
2.38
3.98
3.6
3.7
27.8
27.4
mg/l
0.02
15
89
26
112
2.38
3.98
3.6
3.7
51.8
96.7
mg/l
0.35
15
90
92
610
1.60
3.93
2.5
1.8
—
—
—
0
0
63
378
1.75
3.92
3.3
4.7
0.9
1.0
%
0.12
18
114
115
805
1.54
3.89
4.7
3.5
774.0
276.2
ng/l
0.44
67
601
53
303
1.82
3.88
1.2
1.2
—
—
—
0
0
161
1214
1.45
3.77
6.5
6.6
—
—
—
0
0
22
90
2.50
3.76
1.3
1.2
78.7
4.1
e6/l
0.51
17
67
22
90
2.50
3.76
1.4
1.2
386.7
121.6
e6/l
0.34
17
70
72
454
1.67
3.75
6.9
7.2
0.9
1.2
mmol/l
0.33
58
363
43
233
1.91
3.71
1.5
1.3
33.9
30.2
iu/l
0.21
32
201
14
46
3.09
3.55
1.4
1.3
—
—
—
0
0
25
112
2.29
3.53
2.5
3.4
7.4
7.4
ph
0.44
25
90
77
502
1.62
3.53
1.4
1.5
—
—
—
0
0
537
5077
1.83
3.45
13.6
9.7
24.9
25.2
u/l
0.16
519
4893
31
154
2.07
3.42
2.2
2.1
116.6
3737.6
u/l
1.48
11
66
13
42
3.14
3.39
1.2
1.5
—
—
—
0
0
27
129
2.15
3.29
1.5
1.4
222.7
318.1
ug/g
1.66
16
66
58
358
1.69
3.29
1.3
1.2
117.6
129.9
iu/ml
0.12
16
157
36
192
1.93
3.28
1.8
1.8
—
—
—
0
0
20
84
2.43
3.26
4.3
4.1
—
—
—
0
0
40
222
1.86
3.24
2.5
2.3
—
—
—
0
0
18
72
2.55
3.24
1.0
1.0
1.7
6.0
u/ml
—
7
29
17
67
2.58
3.15
1.0
1.0
0.1
1.0
u/ml
—
8
22
172
1352
1.39
3.12
3.3
3.0
8.2
7.2
mmol/l
1.54
136
1139
161
1254
1.39
3.08
3.5
3.1
991.9
374.6
mg/l
0.43
95
769
23
106
2.22
3.07
1.4
2.0
38.4
37.9
g/l
0.16
17
87
169
1329
1.38
3.05
4.4
3.8
5.0
7.8
mg/mmol
0.71
98
801
51
312
1.70
3.00
1.5
1.4
—
—
—
0
0
54
336
1.67
2.99
7.6
7.4
—
—
—
0
0
526
4982
1.63
2.85
18.5
11.6
—
—
—
0
0
15
59
2.58
2.80
1.3
1.2
—
—
—
0
0
19
84
2.30
2.80
1.1
1.1
1.4
2.4
u/ml
—
7
27
9
23
3.96
2.78
1.0
1.1
—
—
—
0
0
12
42
2.90
2.76
1.2
1.5
3.4
2.6
g/l
—
7
30
12
42
2.90
2.76
1.2
1.5
5.9
6.0
g/l
—
7
30
12
42
2.90
2.76
1.2
1.5
0.3
0.3
g/l
—
7
29
52
334
1.61
2.57
3.3
3.1
71.9
74.2
ng/l
0.10
47
298
5
7
7.19
2.55
1.4
1.0
6.8
5.8
mg/g
—
5
7
134
1049
1.36
2.44
4.0
3.5
—
—
—
0
0
0
65
0.00
2.43
0.0
1.1
—
—
—
0
0
5
8
6.29
2.37
1.4
1.0
—
—
—
0
0
112
857
1.38
2.35
2.7
2.8
2.5
2.5
mmol/l
0.02
100
756
493
4645
1.42
2.33
5.4
4.3
5.9
5.9
mmol/l
0.27
448
4255
16
72
2.26
2.29
1.5
2.3
—
—
—
0
0
27
149
1.85
2.28
1.2
1.2
—
—
—
0
0
15
67
2.27
2.19
1.2
1.6
—
—
—
0
0
28
159
1.80
2.17
1.3
2.3
1.5
1.5
g/l
0.02
23
141
56
382
1.52
2.16
8.3
8.0
121.5
119.2
g/l
0.37
56
371
24
130
1.88
2.15
3.5
3.1
0.3
0.3
g/l
—
5
53
24
130
1.88
2.15
1.2
1.3
—
—
—
0
0
17
81
2.13
2.14
2.1
2.4
—
—
—
0
0
25
138
1.85
2.12
2.2
2.6
—
—
—
0
0
0
56
0.00
2.07
0.0
1.2
—
—
—
0
0
63
446
1.46
2.04
1.5
1.4
—
—
—
0
0
17
83
2.08
2.03
1.1
3.2
32.6
34.0
umol/l
0.10
12
74
5
11
4.57
1.94
1.4
1.0
11766.6
365.5
mu/l
—
5
11
5
11
4.57
1.94
1.4
1.0
69.4
76.8
%
—
5
11
8
27
2.99
1.94
1.3
1.2
—
—
—
0
0
11
45
2.47
1.94
1.1
1.2
—
—
—
0
0
7
23
3.07
1.80
3.7
2.2
—
—
—
0
0
67
493
1.41
1.79
2.5
2.6
6.2
8.3
umol/l
0.97
56
423
360
3298
1.24
1.76
4.1
3.6
—
—
—
0
0
17
89
1.94
1.71
1.5
1.2
—
—
—
0
0
14
68
2.09
1.71
1.1
1.4
1.0
0.6
g/l
—
9
52
17
90
1.92
1.67
1.2
1.8
1.2
0.8
nmol/l
0.89
11
74
6
19
3.18
1.66
1.2
1.5
131.7
172.3
nmol/l
—
6
19
14
69
2.05
1.66
1.4
1.3
—
—
—
0
0
100
795
1.31
1.64
1.7
1.8
—
—
—
0
0
16
84
1.93
1.61
1.1
1.4
—
—
—
0
0
547
5314
1.56
1.61
28.3
18.5
258.3
255.2
e9/l
0.58
537
5180
63
469
1.39
1.59
1.5
1.5
—
—
—
0
0
547
5317
1.55
1.56
28.3
18.5
4.4
4.5
e12/l
1.19
538
5171
547
5318
1.55
1.55
28.4
18.6
6.6
6.6
e9/l
0.03
539
5171
14
71
2.00
1.55
1.3
1.1
—
—
—
0
0
5
15
3.35
1.52
1.4
2.0
—
—
—
0
0
29
186
1.59
1.51
1.0
1.1
—
—
—
0
0
14
72
1.97
1.50
1.4
1.1
—
—
—
0
0
9
37
2.45
1.48
2.8
1.5
—
—
—
0
0
9
37
2.45
1.48
1.0
1.2
—
—
—
0
0
85
671
1.31
1.47
1.4
1.5
—
—
—
0
0
9
38
2.39
1.46
1.3
1.2
—
—
—
0
0
26
164
1.61
1.46
2.0
1.8
20.6
21.3
s
0.48
19
148
78
614
1.31
1.39
1.4
1.2
—
—
—
0
0
45
324
1.42
1.39
1.2
1.3
—
—
—
0
0
20
120
1.69
1.36
1.8
3.1
1.4
1.5
mg/l
0.18
20
111
12
61
1.99
1.33
1.1
1.0
—
—
—
0
0
19
113
1.70
1.33
2.1
3.4
—
—
—
0
0
8
34
2.37
1.29
1.1
1.1
—
—
—
0
0
21
130
1.64
1.28
1.2
1.2
—
—
—
0
0
151
1300
1.22
1.27
1.6
1.6
1.5
1.4
mmol/l
0.97
120
1093
9
45
2.02
1.23
1.4
1.2
—
—
—
0
0
5
19
2.65
1.22
1.0
1.4
—
—
—
0
0
8
37
2.18
1.22
1.1
1.1
—
—
—
0
0
23
149
1.57
1.19
9.0
8.9
—
—
—
0
0
8
40
2.01
1.12
2.3
4.6
—
—
—
0
0
29
201
1.47
1.12
6.2
8.8
—
—
—
0
0
13
73
1.80
1.11
1.5
1.5
—
—
—
0
0
16
96
1.69
1.11
1.1
1.3
—
—
—
0
0
7
32
2.20
1.08
3.1
2.2
555.9
475.2
e6/l
—
7
26
9
47
1.93
1.02
2.2
2.5
—
—
—
0
0
17
107
1.61
1.00
2.4
1.5
—
—
—
0
0
47
363
1.32
0.99
1.1
1.2
—
—
—
0
0
7
36
1.96
0.97
1.4
1.2
—
—
—
0
0
38
496
0.75
0.94
1.3
1.4
—
—
—
0
0
10
55
1.83
0.92
1.0
1.0
—
—
—
0
0
6
28
2.15
0.91
1.2
1.8
—
2112.3
—
0
6
6
29
2.08
0.89
4.3
7.0
—
—
—
0
0
8
42
1.92
0.89
1.1
1.3
—
—
—
0
0
23
162
1.44
0.85
2.0
1.9
3.4
3.2
ug/l
0.02
18
151
13
80
1.64
0.85
1.1
1.1
—
—
—
0
0
13
80
1.64
0.85
1.1
1.1
—
—
—
0
0
6
31
1.95
0.84
1.2
2.5
—
—
—
0
0
11
65
1.71
0.83
1.3
1.2
3.0
7.4
u/ml
—
5
21
16
105
1.54
0.82
2.1
2.1
—
—
—
0
0
23
164
1.42
0.81
6.0
5.1
—
—
—
0
0
497
4834
1.20
0.80
5.4
4.7
2.9
2.8
mmol/l
0.12
461
4463
489
4750
1.19
0.80
5.0
4.2
4.8
4.8
mmol/l
0.14
450
4417
471
4565
1.17
0.77
4.5
3.8
1.4
1.3
mmol/l
4.79
435
4199
6
34
1.77
0.76
1.2
1.1
—
—
—
0
0
7
38
1.85
0.73
3.0
3.4
6.8
20.4
mg/l
—
7
26
22
159
1.40
0.73
1.4
1.3
—
—
—
0
0
11
68
1.63
0.72
2.3
3.7
0.6
1.5
%
1.67
11
57
451
4366
1.15
0.70
16.9
13.3
39.8
39.8
%
0.05
318
3245
104
917
1.16
0.69
5.0
4.6
2.0
2.5
ug/l
0.61
89
821
13
86
1.52
0.66
1.2
1.2
225.0
264.5
u/ml
—
7
53
33
260
1.29
0.65
4.5
4.7
—
—
—
0
0
18
129
1.41
0.64
3.7
2.3
8.3
10.8
mg/l
1.08
18
122
0
20
0.00
0.60
0.0
1.6
—
77861.6
—
0
14
18
131
1.39
0.59
2.2
1.4
—
—
—
0
0
8
53
1.52
0.58
2.9
2.2
—
—
—
0
0
8
53
1.52
0.58
7.3
3.1
—
—
—
0
0
8
54
1.49
0.57
1.1
1.1
1.3
1.4
g/l
—
8
45
25
195
1.29
0.55
2.5
2.8
0.6
0.7
%
1.17
25
188
484
4731
1.14
0.55
5.1
4.2
1.5
1.5
mmol/l
3.52
444
4375
11
74
1.50
0.53
1.2
1.8
—
—
—
0
0
16
118
1.37
0.50
1.1
1.1
—
—
—
0
0
7
46
1.53
0.48
1.4
1.1
—
—
—
0
0
44
374
1.19
0.48
3.0
3.5
6.0
5.8
kpa
0.64
44
367
27
218
1.25
0.47
1.2
1.1
—
167.9
—
0
7
25
200
1.26
0.47
2.5
2.9
1.2
1.3
%
0.05
25
200
20
156
1.29
0.45
2.2
1.4
—
—
—
0
0
11
78
1.42
0.43
1.4
1.1
—
—
—
0
0
25
203
1.24
0.42
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
12
160
0.74
0.40
2.3
4.6
1.7
1.6
%
0.25
12
152
5
35
1.43
0.39
1.4
1.6
1.0
1.1
g/l
—
5
35
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
8
112
0.71
0.37
3.8
4.1
—
—
—
0
0
23
190
1.22
0.35
2.9
3.8
23.5
24.1
mmol/l
0.34
23
176
6
43
1.40
0.35
1.0
1.4
—
—
—
0
0
51
455
1.13
0.33
1.5
1.4
—
—
—
0
0
12
154
0.77
0.32
2.3
4.8
1.2
0.9
%
1.23
12
146
20
166
1.21
0.30
2.2
1.4
—
—
—
0
0
20
167
1.20
0.29
2.2
1.4
—
—
—
0
0
35
308
1.15
0.28
1.7
1.9
—
—
—
0
0
9
120
0.75
0.27
3.7
5.6
0.8
1.3
mmol/l
—
9
108
20
168
1.20
0.27
2.2
1.4
—
—
—
0
0
26
225
1.16
0.26
2.8
3.1
—
—
—
0
0
9
73
1.24
0.25
1.0
1.0
—
—
—
0
0
12
96
1.26
0.24
1.9
3.6
—
—
—
0
0
6
84
0.71
0.24
3.3
6.0
106.7
105.6
mmol/l
—
6
77
6
84
0.71
0.24
3.3
6.0
10.8
11.5
mmol/l
—
6
77
13
106
1.23
0.23
5.4
3.7
22.8
29.3
mg/l
—
7
62
5
38
1.32
0.23
2.6
2.2
—
—
—
0
0
34
304
1.13
0.23
3.1
2.5
—
—
—
0
0
5
39
1.28
0.23
1.0
1.1
—
—
—
0
0
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
5
42
1.19
0.21
2.8
2.1
—
—
—
0
0
5
42
1.19
0.21
1.6
1.3
35.6
31.0
g/l
—
5
37
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
58.4
—
0
6
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
18
155
1.17
0.20
1.4
1.3
283.7
273.6
miu/ml
—
7
76
10
82
1.22
0.17
1.8
1.8
—
—
—
0
0
7
63
1.11
0.17
1.1
1.4
—
—
—
0
0
5
67
0.74
0.17
1.4
1.6
—
—
—
0
0
5
68
0.73
0.17
1.0
1.8
—
—
—
0
0
57
535
1.07
0.16
1.5
1.7
—
—
—
0
0
38
411
0.92
0.16
1.6
1.7
—
—
—
0
0
52
547
0.95
0.11
2.8
2.8
0.6
0.8
ug/l
1.60
30
354
18
165
1.09
0.09
2.3
1.4
—
—
—
0
0
127
1299
0.97
0.08
1.6
1.4
—
—
—
0
0
185
1827
1.02
0.05
2.6
2.7
—
—
—
0
0
47
483
0.97
0.04
2.3
4.3
2.8
17.3
ug/l
0.97
31
394
14
131
1.07
0.03
1.7
1.8
3.1
4.1
iu/l
—
5
49
33
340
0.97
0.03
1.4
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
4.6
—
25.3
—
0
9
5
52
0.96
0.00
3.4
2.3
—
—
—
0
0
0
7
0.00
0.00
0.0
5.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
33.7
—
0
5
0
9
0.00
0.00
0.0
3.9
—
—
—
0
0
7
71
0.99
0.00
1.1
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
5
53
0.94
0.00
3.4
2.3
4.5
3.9
mmol/l
—
5
53
5
53
0.94
0.00
3.4
2.3
107.6
105.8
mmol/l
—
5
53
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_TRIOTHUNS and mortality.

Females

Parameter HR [95% CI] p-value
G6_TRIOTHUNS 1.485 [1.28, 1.73] < 0.001
Birth year 0.997 [0.99, 1.01] 0.513

During the follow-up period (1.1.1998 — 31.12.2019), 381 out of 2062 females with G6_TRIOTHUNS died.

Males

Parameter HR [95% CI] p-value
G6_TRIOTHUNS 1.674 [1.35, 2.07] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 247 out of 930 males with G6_TRIOTHUNS died.

Mortality risk

Mortality risk for people of age

years, who have G6_TRIOTHUNS.

N-year risk Females Males
1 0.131% 0.338%
5 0.889% 1.895%
10 2.321% 4.687%
15 4.569% 8.682%
20 7.835% 14.589%

Relationships between endpoints

Index endpoint: G6_TRIOTHUNS – Other and unspecified trigeminal disorders

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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