This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_OSTEOSARCOMA_EXALLC for full statistics.
Osteosarcoma
C3_OSTEOSARCOMA
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
76 |
4. Check minimum number of eventsNone |
76 |
5. Include endpointsNone |
76 |
6. Filter based on genotype QC (FinnGen only) |
76 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF8
Similar endpoints
↥List of similar endpoints to
Osteosarcoma
based on the number of shared cases.
Similar with more cases:
- Osteosarcoma, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of bone and articular cartilage
- Malignant neoplasm of bone and articular cartilage, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm
- Any event in cancer register
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 76 | 32 | 44 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 22.36 | 17.27 | 26.06 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 71
- Matched controls
- 710
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
+∞
51.4
43
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
+∞
41.8
36
*
130
Kela drug reimbursment
Malignant tumour
50.1
35.9
44
22
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
199.9
34.1
33
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
18.5
17
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
54.4
17.4
20
5
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
63.6
17.0
19
*
L03AA02
ATC
filgrastim; parenteral
50.7
16.3
19
5
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
16.2
15
*
N02AA05
ATC
oxycodone; systemic
11.8
14.7
29
39
NF3AA
NOMESCO Finland
Femur X-ray examination
50.6
13.8
16
*
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
12.9
12
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
42.7
11.8
14
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
31.0
11.7
15
6
N03AX16
ATC
pregabalin; oral
6.7
10.7
31
73
TPX15
NOMESCO Finland
Removal of vascular injection port
+∞
10.7
10
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.6
10.5
46
176
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
24.4
10.3
14
7
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
14.5
10.2
17
15
WX408
NOMESCO Finland
General anesthesy, balanced
5.6
10.2
38
121
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
64.0
9.9
11
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
13.5
9.9
17
16
A03FA01
ATC
metoclopramide; systemic, rectal
7.4
9.9
25
48
JN4BD
NOMESCO Finland
Extensive body CT
10.8
9.9
19
23
A04AA01
ATC
ondansetron; systemic, rectal
14.3
9.6
16
14
1707A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Long bones of lower limb[ALARAAJAN PITKIEN LUIDEN SYÖPÄ,OSTEOSARCOMA]
+∞
9.6
9
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
9.6
9
*
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
+∞
9.6
9
*
B01AB05
ATC
enoxaparin; parenteral
5.6
9.5
33
95
ZXA05
NOMESCO Finland
Left side
5.7
9.5
32
89
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
57.2
8.9
10
*
WW500
NOMESCO Finland
Blood transfusion
31.9
8.8
11
*
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
101.5
8.6
9
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
12.3
8.5
15
15
GD1AD
NOMESCO Finland
Thorax CT examination
14.2
8.5
14
12
C40.11
ICD-10 Finland
Osteosarcoma of the short bones of the upper extremity
+∞
8.5
8
*
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
8.5
8
*
C40.01
ICD-10 Finland
Osteosarcoma of the scapula and the long bones of the upper extremity
+∞
8.5
8
*
9180/3-C40.0
ICD-O-3
Osteosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
8.5
8
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
7.5
8.3
20
35
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
25.5
8.3
11
5
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
9.5
7.9
16
21
WX404
NOMESCO Finland
Intravenous generell anesthesy
5.2
7.6
26
71
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
88.9
7.6
8
*
R4110
NOMESCO Finland
Physiotherapy
4.5
7.5
31
103
9101
FHL
Bone biopsy
+∞
7.4
7
*
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
+∞
7.4
7
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.7
7.3
22
52
ZXA00
NOMESCO Finland
Right side
4.6
6.9
27
84
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.7
6.9
26
78
L03AA13
ATC
pegfilgrastim; parenteral
25.3
6.9
9
*
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
25.3
6.9
9
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
14.2
6.8
11
9
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.8
6.6
38
165
NFQ20
NOMESCO Finland
Amputation of femur
76.3
6.5
7
*
J04AB02
ATC
rifampicin; systemic
76.3
6.5
7
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
20.2
6.4
9
5
N02AX02
ATC
tramadol; systemic, rectal
3.6
6.4
38
170
C40.91
ICD-10 Finland
Osteosarcoma in unspecified locations in the bones and articular cartilage of the extremities
+∞
6.3
6
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
6.3
6
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
6.6
6.3
16
30
WX306
NOMESCO Finland
Lumbar epidural anesthesy
7.0
6.3
15
26
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
16.9
6.1
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
11
10
12.69
10.40
1.5
1.5
—
—
—
0
0
35
120
4.55
9.58
8.2
2.3
—
—
—
0
0
50
240
4.17
8.30
26.3
8.1
1.2
1.2
mmol/l
0.63
42
212
10
11
10.32
8.27
2.3
1.9
—
—
—
0
0
23
81
3.64
5.70
2.3
2.0
—
—
—
0
0
49
287
2.99
4.98
23.2
6.8
8.6
11.6
umol/l
2.39
49
275
13
33
4.55
4.94
27.3
6.4
0.9
0.7
%
0.70
13
33
13
33
4.55
4.94
27.1
6.4
1.3
1.5
%
0.49
13
33
9
10
10.02
4.93
2.0
2.2
—
—
—
0
0
44
245
2.89
4.88
8.5
3.8
—
—
—
0
0
8
8
10.99
4.64
1.6
2.1
—
—
—
0
0
9
12
8.33
4.49
1.9
2.0
—
—
—
0
0
54
349
2.89
4.31
30.4
10.2
3.9
4.0
e9/l
0.20
49
299
16
54
3.49
4.14
2.8
1.8
—
—
—
0
0
16
55
3.42
4.02
2.6
1.6
—
—
—
0
0
8
13
6.73
3.60
2.0
2.1
—
—
—
0
0
6
7
9.17
3.32
1.5
1.9
—
—
—
0
0
13
44
3.36
3.32
3.0
2.0
96.5
70.8
ml/min/173m2
—
8
20
6
8
8.02
3.11
1.2
2.4
—
—
—
0
0
5
5
10.57
3.02
1.4
1.0
—
—
—
0
0
6
9
7.12
2.92
1.2
2.2
—
—
—
0
0
12
43
3.13
2.79
5.7
3.9
—
—
—
0
0
9
24
4.11
2.77
1.6
1.5
—
—
—
0
0
19
90
2.48
2.67
4.2
2.8
12.5
15.1
umol/l
0.60
19
83
67
549
2.86
2.62
26.4
10.7
93.2
91.1
ml/min/173m2
0.26
62
441
12
45
2.98
2.59
49.8
8.6
25.0
24.6
mmol/l
0.31
12
45
16
71
2.59
2.56
8.1
3.1
4.2
9.5
umol/l
0.61
16
62
32
198
2.06
2.36
4.9
3.0
—
—
—
0
0
7
19
3.95
2.21
3.0
3.9
18.5
445.9
u/ml
—
7
14
13
58
2.50
2.04
15.9
8.3
—
—
—
0
0
5
13
4.04
1.74
1.2
1.2
—
—
—
0
0
26
164
1.89
1.74
3.0
2.5
0.3
0.3
e6/l
0.11
21
122
6
23
2.74
1.39
1.8
2.6
—
—
—
0
0
69
617
2.28
1.39
37.5
12.2
32.3
22.8
mg/l
1.09
62
450
15
85
1.95
1.35
4.7
2.7
2.6
2.4
g/l
0.30
15
78
25
168
1.73
1.33
4.0
2.6
56.4
54.8
u/l
0.07
25
160
22
148
1.68
1.15
4.3
2.2
1973.8
231.3
u/l
0.56
22
141
71
654
2.30
1.12
26.9
9.3
30.3
27.8
u/l
0.56
71
631
25
177
1.61
1.07
4.2
3.5
11.8
33.0
ng/l
2.59
19
98
7
37
1.98
0.97
2.0
1.5
—
—
—
0
0
44
507
0.69
0.81
3.5
3.6
—
—
—
0
0
9
54
1.75
0.78
11.4
3.5
5.5
5.0
kpa
—
9
49
5
23
2.25
0.77
2.0
2.0
—
—
—
0
0
5
23
2.25
0.77
1.0
1.1
—
—
—
0
0
5
23
2.25
0.77
1.0
1.1
—
—
—
0
0
52
456
1.44
0.72
4.7
3.0
46.7
42.5
u/l
0.25
52
434
8
52
1.60
0.62
12.8
3.5
2.3
0.9
mmol/l
—
8
37
0
21
0.00
0.61
0.0
1.4
—
—
—
0
0
24
191
1.37
0.56
1.8
1.8
103.3
93.2
pmol/l
—
10
108
8
118
0.64
0.50
1.9
2.3
—
—
—
0
0
9
129
0.66
0.48
1.8
2.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.5
—
—
—
0
0
6
44
1.39
0.35
1.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
25
272
0.88
0.15
6.3
3.6
0.0
0.0
estimate
—
6
48
22
202
1.13
0.12
7.0
3.6
—
—
—
0
0
28
266
1.08
0.07
6.0
3.6
0.0
0.0
estimate
—
6
52
11
101
1.10
0.04
2.3
2.4
1.3
0.8
e6/l
—
6
59
15
142
1.07
0.02
2.3
1.5
1.4
1.5
mmol/l
0.10
15
120
15
142
1.07
0.02
8.6
3.6
0.0
0.0
estimate
—
6
51
16
153
1.06
0.01
1.4
1.6
—
—
—
0
0
26
266
0.97
0.00
7.5
5.0
0.0
0.0
estimate
—
6
51
15
146
1.03
0.00
1.8
4.2
27.5
21.3
%
—
8
71
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
91.0
—
0
5
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
0.00
1.7
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
935.7
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
158.4
—
0
5
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_OSTEOSARCOMA – Osteosarcoma
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).