This is a non-core endpoint: only basic statistics are computed.
Osteosarcoma
C3_OSTEOSARCOMA
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
83 |
4. Check minimum number of eventsNone |
83 |
5. Include endpointsNone |
83 |
6. Filter based on genotype QC (FinnGen only) |
81 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- First used in FinnGen datafreeze
- DF8
Similar endpoints
↥List of similar endpoints to
Osteosarcoma
based on the number of shared cases.
Similar with more cases:
- Osteosarcoma, including Hilmo
- Malignant neoplasm of bone and articular cartilage
- Solid cancers, helper endpoint
- Malignant neoplasm
- Any event in cancer register
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 81 | 35 | 46 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 22.31 | 17.39 | 26.06 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 83
- Matched controls
- 830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
64.1
53
*
9180/3-C40.2
ICD-O-3
Osteosarcoma, NOS, of long bones of lower limb and associated joints
+∞
61.2
51
*
C40.21
ICD-10 Finland
Osteosarcoma of the long bones of the lower extremity
+∞
50.2
43
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
251.4
42.2
40
*
N02AA05
ATC
oxycodone; systemic
18.4
38.6
40
40
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
24.1
22
*
A03FA01
ATC
metoclopramide; systemic, rectal
11.2
23.9
32
44
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
87.8
23.4
25
*
NF3AA
NOMESCO Finland
Femur X-ray examination
82.9
22.3
24
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
50.1
21.3
25
7
L03AA02
ATC
filgrastim; parenteral
259.4
20.5
20
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
19.5
18
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
9.0
17.9
27
42
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.9
17.8
32
61
A04AA01
ATC
ondansetron; systemic, rectal
46.0
17.7
21
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
7.1
17.5
56
187
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
17.3
16
*
B01AB05
ATC
enoxaparin; parenteral
6.7
16.7
41
106
GD1AD
NOMESCO Finland
Thorax CT examination
21.9
16.5
24
15
ZXA05
NOMESCO Finland
Left side
6.8
16.4
37
88
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
16.2
15
*
C40.29
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity other or unspecified histology
+∞
16.2
15
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
16.2
15
*
ZXE20
NOMESCO Finland
More than three and less than five hours
7.8
16.1
28
51
WX402
NOMESCO Finland
General anaesthesia
6.9
15.9
33
72
NG4AA
NOMESCO Finland
Lower leg X-ray examination
24.4
15.7
22
12
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.5
15.6
36
87
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
15.0
14
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
25.8
14.6
20
10
H02AB02
ATC
dexamethasone; systemic
65.1
14.4
16
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
65.1
14.4
16
*
N03AX16
ATC
[U] pregabalin
5.9
14.0
36
95
R4110
NOMESCO Finland
Physiotherapy
5.7
13.9
41
122
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
13.9
13
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
13.9
13
*
L03AA13
ATC
pegfilgrastim; parenteral
166.0
13.9
14
*
WX408
NOMESCO Finland
General anesthesy, balanced
5.4
13.0
41
128
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
83.0
13.0
14
*
WW500
NOMESCO Finland
Blood transfusion
36.0
12.1
15
5
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.0
11.9
21
21
NGB30
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part - connected prosthesis
+∞
11.7
11
*
C40.01
ICD-10 Finland
Osteosarcoma of the scapula and the long bones of the upper extremity
+∞
11.7
11
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
41.5
11.7
14
*
JN4BD
NOMESCO Finland
Extensive body CT
15.0
11.6
19
16
ZXE10
NOMESCO Finland
More than one and less than three hours
4.7
11.0
44
162
Z51.5
ICD-10 Finland
Palliative care
38.0
10.7
13
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
10.6
10
*
C40.11
ICD-10 Finland
Osteosarcoma of the short bones of the upper extremity
+∞
10.6
10
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
10.6
10
*
9180/3-C40.0
ICD-O-3
Osteosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.6
10
*
NGR30
NOMESCO Finland
Extensive or radikal excision of tumor of knee or lower leg
+∞
10.6
10
*
1707A
ICD-9 Finland
Malignant neoplasm of bone and articular cartilage, Long bones of lower limb[ALARAAJAN PITKIEN LUIDEN SYÖPÄ,OSTEOSARCOMA]
+∞
10.6
10
*
ZXA00
NOMESCO Finland
Right side
4.7
9.8
31
94
TPX15
NOMESCO Finland
Removal of vascular injection port
112.3
9.6
10
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
8.7
9.6
21
31
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
9.6
9
*
ZXE00
NOMESCO Finland
One hour or less
4.1
9.4
49
214
JN4AD
NOMESCO Finland
Body CT examination
12.9
9.3
16
15
ZXE30
NOMESCO Finland
More than five and less than seven hours
12.9
9.3
16
15
TPH07
NOMESCO Finland
Cathetrisation of artery
8.4
9.1
20
30
WZC30
NOMESCO Finland
Teaching
5.5
8.9
20
45
WZC00
NOMESCO Finland
Treatment plan or consultation
3.9
8.8
45
192
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
15.0
8.7
14
11
J04AB02
ATC
rifampicin; systemic
99.8
8.6
9
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
5.8
8.6
18
38
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
8.5
8
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
8.5
8.3
18
26
WX404
NOMESCO Finland
Intravenous generell anesthesy
4.2
8.3
29
94
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
17.2
8.0
12
8
WX302
NOMESCO Finland
Thoracal epidural anesthesy
17.2
8.0
12
8
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
5.2
7.7
18
42
N02BF02
ATC
pregabalin; oral
12.6
7.6
13
12
N02AX02
ATC
tramadol; systemic, rectal
3.6
7.6
43
192
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.1
7.4
18
31
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
10.3
7.4
14
16
Z89.6
ICD-10 Finland
Acquired absence of leg above knee
+∞
7.4
7
*
9101
FHL
Bone biopsy
+∞
7.4
7
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
+∞
7.4
7
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
7.4
7
*
NFQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of hip or femur
+∞
7.4
7
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
7.4
7
*
J01MA12
ATC
levofloxacin; systemic
4.4
7.3
22
63
ZXD10
NOMESCO Finland
Scheduled procedure
3.5
7.3
43
196
J01FF01
ATC
clindamycin; systemic
3.6
7.0
31
117
JN4CD
NOMESCO Finland
Very extensive body CT
43.8
6.9
8
*
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
43.8
6.9
8
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.9
6.8
25
83
A04AA02
ATC
granisetron; systemic, transdermal
75.4
6.5
7
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
75.4
6.5
7
*
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
75.4
6.5
7
*
ZZA00
NOMESCO Finland
Split skin graft
29.1
6.4
8
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
29.1
6.4
8
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
6.3
6
*
C40.91
ICD-10 Finland
Osteosarcoma in unspecified locations in the bones and articular cartilage of the extremities
+∞
6.3
6
*
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
+∞
6.3
6
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
6.3
6
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
6.3
6
*
GDA20
NOMESCO Finland
Excision of lesion of lung
+∞
6.3
6
*
GDB10
NOMESCO Finland
Wedge resection of lung
+∞
6.3
6
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
9.8
6.3
12
14
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.7
6.0
17
36
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
17
0
+∞
18.40
32.5
0.0
0.37
—
umol/l
—
17
0
41
115
6.07
15.08
8.5
2.1
—
—
—
0
0
30
69
6.24
13.50
2.5
1.6
—
—
—
0
0
57
249
5.12
11.58
35.1
7.9
1.20
1.22
mmol/l
1.11
50
226
22
47
6.01
10.48
2.8
1.5
—
—
—
0
0
21
44
6.05
10.19
28.6
14.2
8.60
9.05
mmol/l
0.09
21
44
21
44
6.05
10.19
48.6
7.4
104.86
106.14
mmol/l
0.68
21
44
22
49
5.75
10.00
2.6
1.4
—
—
—
0
0
17
17
12.24
9.57
21.9
12.2
23.85
23.60
mmol/l
0.12
17
17
56
268
4.35
9.43
25.2
3.7
8.52
11.44
umol/l
2.39
56
256
18
23
9.67
8.95
22.1
11.2
0.89
0.71
%
0.73
18
23
18
23
9.67
8.95
21.9
11.3
1.28
1.51
%
0.49
18
23
51
236
4.01
8.85
7.3
2.2
—
—
—
0
0
16
18
10.71
8.51
8.9
3.9
3.58
4.17
g/l
0.49
16
18
12
8
17.23
7.99
2.3
1.6
—
—
—
0
0
61
347
3.86
7.23
39.1
8.0
3.78
4.06
e9/l
0.41
53
294
47
230
3.41
7.03
13.0
9.1
1.00
1.25
inr
3.49
11
66
12
12
11.45
6.79
1.6
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
13
16
9.40
6.62
17.4
3.4
0.23
0.29
u/ml
—
7
11
14
20
8.18
6.55
2.1
1.4
—
—
—
0
0
11
11
11.31
6.25
1.8
1.5
—
—
—
0
0
11
11
11.31
6.25
1.7
1.2
—
—
—
0
0
10
10
11.17
5.70
1.6
1.2
—
—
—
0
0
10
10
11.17
5.70
1.6
1.2
—
—
—
0
0
8
5
17.47
5.53
1.4
1.2
—
—
—
0
0
9
8
12.42
5.43
1.6
1.3
—
—
—
0
0
17
50
4.02
5.36
72.6
13.3
25.25
24.29
mmol/l
1.11
17
50
20
67
3.62
5.26
7.1
3.5
4.08
10.72
umol/l
0.74
20
57
39
197
2.85
5.13
4.8
4.0
—
—
—
0
0
12
22
6.18
4.81
7.1
3.4
215.83
183.05
%
0.67
12
22
33
161
2.74
4.54
3.3
3.9
0.29
0.16
e6/l
0.46
24
114
22
88
3.04
4.32
4.0
2.8
13.59
15.68
umol/l
0.48
22
80
14
36
4.46
4.24
2.9
1.9
98.11
75.38
ml/min/173m2
—
9
16
13
32
4.62
4.12
5.2
3.0
—
—
—
0
0
12
29
4.65
3.89
1.8
1.7
—
—
—
0
0
7
8
9.41
3.85
1.4
1.0
—
—
—
0
0
7
8
9.41
3.85
1.1
1.3
—
—
—
0
0
9
16
6.16
3.77
1.9
3.1
—
—
—
0
0
7
11
6.83
3.25
1.1
1.2
—
—
—
0
0
18
79
2.63
2.93
4.4
2.8
2.45
2.37
g/l
0.18
18
74
71
562
2.82
2.91
29.2
7.5
93.67
91.14
ml/min/173m2
0.34
65
449
5
6
8.76
2.78
1.2
1.0
—
—
—
0
0
6
11
5.78
2.59
1.5
1.8
—
—
—
0
0
7
16
4.67
2.53
88.1
4.2
1.30
1.22
%
—
7
16
7
17
4.39
2.41
1.9
2.1
—
—
—
0
0
13
53
2.72
2.41
15.9
5.5
—
—
—
0
0
76
663
2.73
2.10
42.9
9.7
32.28
21.09
mg/l
1.57
69
467
6
16
3.95
1.97
1.7
1.7
—
—
—
0
0
6
16
3.95
1.97
2.0
2.0
—
—
—
0
0
78
699
2.92
1.83
30.7
7.6
35.18
26.87
u/l
1.50
78
675
12
55
2.38
1.77
9.8
9.1
1.21
1.08
mmol/l
0.04
12
39
6
20
3.15
1.61
1.0
1.1
—
—
—
0
0
6
20
3.15
1.61
1.0
1.1
—
—
—
0
0
5
15
3.48
1.54
3.0
2.5
—
—
—
0
0
5
15
3.48
1.54
1.0
1.3
—
—
—
0
0
27
180
1.74
1.46
3.9
2.2
54.78
80.24
u/l
0.50
27
175
58
477
1.72
1.42
5.0
3.1
56.95
40.73
u/l
1.18
58
457
27
182
1.72
1.40
4.0
2.9
11.36
54.57
ng/l
1.40
21
108
5
17
3.06
1.38
1.8
1.6
185.20
103.00
u/ml
—
5
6
17
106
1.76
1.14
3.0
3.1
1.35
0.80
e6/l
—
6
61
23
159
1.62
1.06
4.2
2.1
1945.74
234.60
u/l
0.58
23
152
26
190
1.54
0.95
1.8
1.7
98.30
94.19
pmol/l
0.11
11
107
34
272
1.42
0.78
6.7
3.6
0.00
0.00
estimate
—
7
54
7
44
1.64
0.67
1.0
1.3
—
—
—
0
0
5
29
1.77
0.65
1.4
1.4
—
—
—
0
0
19
142
1.44
0.61
3.2
3.7
6.85
9.25
mg/mmol
0.20
11
100
10
143
0.66
0.53
1.7
2.4
—
—
—
0
0
32
271
1.29
0.48
9.2
5.1
0.00
0.00
estimate
—
7
50
9
130
0.66
0.47
1.8
2.3
—
—
—
0
0
22
180
1.30
0.42
1.3
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
2.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
51
551
0.81
0.36
3.9
3.6
—
—
—
0
0
31
278
1.18
0.25
7.0
3.6
0.00
0.00
estimate
—
7
49
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
6.93
—
0
10
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
206.38
—
0
10
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
23
207
1.15
0.17
7.6
3.5
—
—
—
0
0
16
145
1.13
0.10
9.3
3.6
0.00
0.00
estimate
—
7
51
15
158
0.94
0.02
2.3
1.6
1.44
1.56
mmol/l
0.17
15
136
15
145
1.04
0.00
1.8
3.5
27.45
23.26
%
—
8
72
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
7.38
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
97
0.92
-0.00
1.7
1.5
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_OSTEOSARCOMA – Osteosarcoma
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).