No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
98 |
4. Check minimum number of eventsNone |
98 |
5. Include endpointsNone |
98 |
6. Filter based on genotype QC (FinnGen only) |
98 |
Control definitions (FinnGen only)
- Control exclude
- E4_NUTRIDEF
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E61
- Name in latin
- Deficientia magnesii
Similar endpoints
↥List of similar endpoints to
Magnesium deficiency
based on the number of shared cases.
Similar with more cases:
- Other nutritional deficiencies
- Endocrine, nutritional and metabolic diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 425 | 193 | 228 |
| Only index persons | 408 | 188 | 220 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 65.03 | 66.98 | 63.78 |
| Only index persons | 65.36 | 67.07 | 63.90 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 98 | 48 | 50 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 66.32 | 67.47 | 65.22 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 86
- Matched controls
- 860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E61.2
ICD-10 Finland
Magnesium deficiency
+∞
123.8
86
*
E87.6
ICD-10 Finland
Hypokalaemia
42.7
22.2
27
9
E83.51
ICD-10 Finland
Hypocalcemia
240.3
19.4
19
*
N02AA05
ATC
oxycodone; systemic
8.8
14.5
34
59
A03FA01
ATC
metoclopramide; systemic, rectal
6.9
14.3
43
108
A49.9
ICD-10 Finland
Bacterial infection, unspecified
9.2
14.2
32
52
TPH04
NOMESCO Finland
Cathetrisation of vein
6.8
14.0
43
110
E83.4
ICD-10 Finland
Disorders of magnesium metabolism
+∞
13.9
13
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
7.5
13.8
37
78
R4190
NOMESCO Finland
Nutritional therapy
18.9
11.4
17
11
WW500
NOMESCO Finland
Blood transfusion
18.9
11.4
17
11
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
+∞
10.6
10
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
14.8
10.4
17
14
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
10.1
10.1
20
25
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
17.8
9.9
15
10
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
9.7
9.8
20
26
C03CA01
ATC
furosemide; systemic
4.8
9.6
39
127
130
Kela drug reimbursment
Malignant tumour
8.1
9.6
22
35
H02AB02
ATC
dexamethasone; systemic
6.2
9.2
26
56
ZX120
NOMESCO Finland
Intravenous
7.2
8.9
22
39
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.9
8.9
33
97
R53
ICD-10 Finland
Malaise and fatigue
4.9
8.7
32
93
E53.8
ICD-10 Finland
Deficiency of other specified B group vitamins
99.4
8.6
9
*
C03DA01
ATC
spironolactone; oral
6.3
8.4
23
47
R11
ICD-10 Finland
Nausea and vomiting
9.3
8.4
17
22
D64.9
ICD-10 Finland
Anaemia, unspecified
6.8
8.2
21
39
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
15.0
8.2
13
10
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
12.6
8.1
14
13
A02BC02
ATC
pantoprazole; systemic
4.4
7.9
71
444
AA1AD
NOMESCO Finland
CT of head and brain
4.1
7.9
36
128
R56.8
ICD-10 Finland
Other and unspecified convulsions
9.1
7.8
16
21
TPH07
NOMESCO Finland
Cathetrisation of artery
5.4
7.7
24
57
WX892
NOMESCO Finland
Monitored bed care
6.4
7.5
20
39
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
6.2
7.4
20
40
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
11.5
7.3
13
13
WF004
NOMESCO Finland
Palliative radiotherapy
33.1
7.3
9
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.7
7.3
40
163
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.6
7.2
44
193
XF600
NOMESCO Finland
Bloodpressure measurement
7.6
7.0
16
25
A01
ICPC
Pain general/multiple sites
7.6
7.0
16
25
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
5.4
7.0
21
48
K92.1
ICD-10 Finland
Melaena
9.1
6.9
14
18
JDB10
NOMESCO Finland
Percutaneous gastrostomy
18.6
6.9
10
6
Z51.5
ICD-10 Finland
Palliative care
8.0
6.9
15
22
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.7
6.9
35
133
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
6.7
54
287
UJF32
NOMESCO Finland
Coloscopy
3.6
6.6
35
137
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.8
6.6
31
111
J01MA12
ATC
levofloxacin; systemic
4.0
6.5
28
92
E86
ICD-10 Finland
Volume depletion
75.2
6.5
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
6.4
41
183
J01MA02
ATC
ciprofloxacin; systemic
3.2
6.4
47
234
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
29.0
6.3
8
*
103
Kela drug reimbursment
Diabetes, insulin-treated
3.5
6.2
35
141
JN3AD
NOMESCO Finland
Abdominal CT examination
6.8
6.2
15
26
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.2
6.1
24
73
Mortality – FinRegistry
↥Association
Association between endpoint E4_MG_DEF and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have E4_MG_DEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: E4_MG_DEF – Magnesium deficiency
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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