This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
26 |
4. Check minimum number of eventsNone |
26 |
5. Include endpointsNone |
26 |
6. Filter based on genotype QC (FinnGen only) |
26 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
APECED
based on the number of shared cases.
Similar with more cases:
- Autoimmune polyglandular failure
- Polyglandular dysfunction
- Disorders of other endocrine glands
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 26 | 15 | 11 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | 24.36 | 30.64 | 15.79 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3023368) Bacteria identified in Blood by Culture
19
31
19.68
10.38
7.8
3.7
—
—
—
0
0
(3014576) Chloride [Moles/volume] in Serum or Plasma
12
14
15.06
10.20
10.2
3.6
mmol/l
102.1
104.9
0.87
12
14
(3024354) Oxygen [Partial pressure] in Venous blood
12
7
30.01
9.16
8.1
3.9
kpa
4.7
4.8
—
12
7
(3010838) Calcium [Moles/time] in 24 hour Urine
8
0
+∞
8.81
2.4
0.0
—
—
—
0
0
(3021447) Carbon dioxide [Partial pressure] in Venous blood
12
9
23.25
8.43
8.8
8.8
kpa
5.7
6.0
—
12
9
(3000991) Gas panel - Venous blood
11
8
22.46
7.75
11.1
2.8
—
—
—
0
0
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
21
66
12.22
7.44
59.7
4.3
mmol/l
1.1
1.2
3.96
21
60
(3012544) pH of Venous blood
11
9
19.92
7.42
6.9
8.8
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
20
58
11.48
7.40
4.8
1.6
pmol/l
91.0
94.2
0.17
14
30
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
10
15
10.21
6.85
3.4
2.1
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
10
15
10.21
6.85
3.3
1.9
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
15
37
8.22
6.73
8.5
2.2
e6/l
0.0
0.5
0.67
15
24
(3012565) Volume of 24 hour Urine
6
0
+∞
6.50
3.0
0.0
ml
3293.3
—
—
6
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
26
140
+∞
6.49
15.0
6.5
u/l
75.9
71.5
0.32
26
133
(3000494) Fungus identified in Specimen by Culture
11
20
8.80
6.43
2.5
1.5
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
18
53
8.70
6.21
8.5
2.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
12
25
8.06
6.21
1.4
1.2
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
18
55
8.30
6.00
5.9
6.5
inr
1.0
1.2
—
9
16
(3020779) Urea [Moles/volume] in Serum or Plasma
9
8
16.29
5.81
17.3
14.0
mmol/l
8.1
4.9
—
9
8
(3002582) Erythrocytes [#/volume] in Urine
15
43
6.88
5.63
8.7
2.3
e6/l
6.1
13.6
1.00
15
32
(37021550) Renin [Units/volume] in Plasma --upright
5
0
+∞
5.37
3.0
0.0
mu/l
336.2
—
—
5
0
(36304419) Bacteria [Presence] in Urine
14
39
6.61
5.37
9.0
2.3
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
16
54
6.10
4.91
8.6
3.1
e6/l
6.7
5.3
0.13
16
36
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
10
22
6.76
4.77
4.3
2.0
—
—
—
0
0
(3016502) Oxygen saturation in Arterial blood
8
9
12.16
4.66
13.5
4.8
%
94.9
93.2
—
8
9
(3018010) Neutrophils/100 leukocytes in Blood
21
101
6.57
4.35
9.5
5.3
%
59.5
55.4
0.72
21
96
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
7
7
13.05
4.29
20.4
1.9
mmol/l
26.6
25.2
—
7
7
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
7
7
13.05
4.29
1.7
1.9
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
16
61
5.22
4.09
1.9
1.5
u/ml
0.6
0.9
—
7
14
(3002173) Hemoglobin [Mass/volume] in Arterial blood
7
8
11.39
4.05
15.3
5.1
g/l
116.4
135.4
—
7
8
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
6
5
14.96
3.97
11.7
1.8
%
0.5
1.0
—
6
5
(3004119) Hemoglobin [Mass/volume] in Venous blood
6
5
14.96
3.97
8.2
12.8
g/l
126.5
132.6
—
6
5
(3014007) Fractional oxyhemoglobin in Arterial blood
6
6
12.45
3.70
11.7
1.8
%
92.8
88.1
—
6
6
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
6
6
12.45
3.70
6.8
3.7
%
1.8
1.5
—
6
6
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
6
6
12.45
3.70
11.7
1.8
%
1.5
3.1
—
6
6
(3006504) Eosinophils/100 leukocytes in Blood
20
99
5.39
3.64
13.5
5.3
%
1.9
3.0
1.72
20
93
(3019069) Monocytes/100 leukocytes in Blood
20
100
5.30
3.62
13.7
6.1
%
9.3
8.2
0.86
20
95
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
26
183
+∞
3.54
15.0
3.6
mmol/mol
45.9
38.7
1.44
26
174
(40760892) CBC W Ordered Manual Differential panel - Blood
15
60
4.55
3.48
13.7
2.8
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
11
8.22
3.44
1.1
1.1
—
—
—
0
0
(40758558) Short blood count panel - Blood
12
41
4.58
3.39
4.5
4.3
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
19
96
4.61
3.26
14.2
5.6
%
0.7
0.7
0.08
19
90
(3014111) Lactate [Moles/volume] in Serum or Plasma
6
8
9.30
3.24
9.7
3.0
mmol/l
1.1
1.2
—
6
8
(3019060) Gas panel - Arterial blood
6
8
9.30
3.24
14.5
5.0
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
5
5
11.91
3.11
4.4
1.4
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
7
14
6.40
2.96
13.0
2.7
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
7
14
6.40
2.96
4.0
1.9
—
—
—
0
0
(3018677) aPTT in Platelet poor plasma by Coagulation assay
9
25
4.93
2.92
2.9
2.6
s
27.9
29.7
—
9
25
(42870588) Differential panel, method unspecified - Blood
15
67
3.93
2.87
13.2
5.4
—
—
—
0
0
(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction
6
12
6.13
2.56
1.5
1.8
u/l
202.2
235.1
—
6
12
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
6
12
6.13
2.56
5.7
2.1
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
18
100
3.58
2.50
9.3
3.8
estimate
0.0
0.0
—
8
15
(3031040) Bacteria [#/volume] in Urine by Automated count
20
118
3.99
2.49
7.6
3.4
—
—
—
0
0
(3023103) Potassium [Moles/volume] in Serum or Plasma
26
204
+∞
2.43
59.7
9.1
mmol/l
3.9
3.9
0.25
26
199
(3025941) Bacteria identified in Stool by Culture
6
13
5.64
2.42
1.8
1.2
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
18
102
3.47
2.24
7.9
2.5
estimate
0.0
0.0
—
8
15
(3035350) Ketones [Presence] in Urine by Test strip
18
102
3.47
2.24
7.9
2.5
estimate
0.0
0.0
—
8
16
(3020961) Endomysium IgA Ab [Titer] in Serum
5
10
5.89
2.17
1.0
1.3
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
15
86
2.76
1.66
8.7
2.4
—
—
—
0
0
(3022145) Colonoscopy Study observation
6
21
3.39
1.61
1.2
1.2
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
9
43
2.66
1.50
7.0
1.9
—
—
—
0
0
(3015736) pH of Urine
14
81
2.58
1.47
5.7
2.3
—
—
—
0
0
(3044889) 12 lead EKG panel
19
131
2.66
1.42
4.9
2.7
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
8
37
2.67
1.36
5.3
2.9
—
—
—
0
0
(3033658) Prothrombin time (PT) actual/Normal
9
45
2.52
1.22
9.7
3.0
%
86.1
97.6
—
9
45
(3044640) Blood type and Crossmatch panel - Blood
10
54
2.38
1.16
2.7
2.0
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
28
0.00
1.05
0.0
2.1
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
26
229
+∞
1.04
58.0
9.2
umol/l
90.6
73.2
1.46
26
229
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
0
32
0.00
1.03
0.0
1.5
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
13
83
2.13
1.00
4.0
4.0
—
—
—
0
0
(3013512) EKG study
8
43
2.24
0.99
4.5
2.6
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
11
69
2.03
0.86
9.2
2.1
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
24
0.00
0.84
0.0
1.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
26
234
+∞
0.83
31.0
9.9
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
18
138
1.98
0.83
8.0
3.7
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
5
27
2.05
0.73
5.2
2.3
ng/l
226.0
694.6
—
5
21
(3042936) Bacteria identified in Isolate by Culture
5
29
1.89
0.67
1.6
1.9
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
6
34
1.99
0.64
2.7
1.6
umol/l
276.5
13034.0
—
6
28
(3001019) Free T4 and TSH panel - Serum or Plasma
0
19
0.00
0.63
0.0
1.6
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
22
0.00
0.62
0.0
1.5
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
7
48
1.62
0.52
1.7
1.6
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
16
0.00
0.42
0.0
1.4
—
—
—
0
0
(1002224) Polysomnography panel
0
17
0.00
0.42
0.0
1.2
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
0
17
0.00
0.42
0.0
1.6
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
6
42
1.55
0.39
3.3
1.7
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
5
73
0.61
0.31
1.2
1.8
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
21
223
0.70
0.25
27.4
10.7
%
39.3
42.0
1.71
15
192
(3050129) First trimester maternal screen panel - Serum or Plasma
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma
0
14
0.00
0.20
0.0
2.5
—
149.0
—
0
6
(1761868) Lipid panel - Serum or Plasma
10
99
1.02
0.00
5.7
2.4
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
3.8
—
0
6
(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
8
79
1.02
0.00
2.1
1.7
—
—
—
0
0
(3000081) cloZAPine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
15.2
—
1181.5
—
0
6
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
21
209
1.02
0.00
7.9
3.2
mmol/l
1.1
1.2
0.61
21
192
(3008832) Norclozapine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
11.8
—
659.8
—
0
6
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
0.9
—
0
5
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
19
191
0.98
0.00
4.3
3.7
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
6
57
1.07
0.00
1.3
1.7
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
2.6
—
68.7
—
0
7
(3042975) Streptococcus sp identified in Isolate by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4034850)
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
(3003888) Timothy IgE Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.0
—
8.4
—
0
5
(40768793) Breast Pathology biopsy report
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40768443) Skin Pathology biopsy report
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(4094501)
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: E4_APECED – APECED
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).