This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
26 |
4. Check minimum number of eventsNone |
26 |
5. Include endpointsNone |
26 |
6. Filter based on genotype QC (FinnGen only) |
26 |
Control definitions (FinnGen only)
- Control exclude
- E4_ENDOGLAND
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
APECED
based on the number of shared cases.
Similar with more cases:
- Autoimmune polyglandular failure
- Polyglandular dysfunction
- Disorders of other endocrine glands
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 26 | 15 | 11 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | 24.36 | 30.64 | 15.79 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
12
14
15.06
10.20
10.2
3.6
102.1
104.9
mmol/l
0.87
12
14
12
9
23.25
8.43
8.8
8.8
5.7
6.0
kpa
—
12
9
21
66
12.22
7.44
59.7
4.3
1.1
1.2
mmol/l
3.96
21
60
20
58
11.48
7.40
4.8
1.6
91.0
94.2
pmol/l
0.17
14
30
10
15
10.21
6.85
3.4
2.1
—
—
—
0
0
10
15
10.21
6.85
3.3
1.9
—
—
—
0
0
15
37
8.22
6.73
8.5
2.2
0.0
0.5
e6/l
0.67
15
24
26
140
+∞
6.49
15.0
6.5
75.9
71.5
u/l
0.32
26
133
18
53
8.70
6.21
8.5
2.4
—
—
—
0
0
10
22
6.76
4.77
4.3
2.0
—
—
—
0
0
7
7
13.05
4.29
20.4
1.9
26.6
25.2
mmol/l
—
7
7
7
7
13.05
4.29
1.7
1.9
—
—
—
0
0
16
61
5.22
4.09
1.9
1.5
0.6
0.9
u/ml
—
7
14
6
6
12.45
3.70
11.7
1.8
1.5
3.1
%
—
6
6
26
183
+∞
3.54
15.0
3.6
45.9
38.7
mmol/mol
1.44
26
174
5
5
11.91
3.11
4.4
1.4
—
—
—
0
0
9
25
4.93
2.92
2.9
2.6
27.9
29.7
s
—
9
25
6
12
6.13
2.56
1.5
1.8
202.2
235.1
u/l
—
6
12
6
12
6.13
2.56
5.7
2.1
—
—
—
0
0
18
100
3.58
2.50
9.3
3.8
0.0
0.0
estimate
—
8
15
26
204
+∞
2.43
59.7
9.1
3.9
3.9
mmol/l
0.25
26
199
18
102
3.47
2.24
7.9
2.5
0.0
0.0
estimate
—
8
15
18
102
3.47
2.24
7.9
2.5
0.0
0.0
estimate
—
8
16
15
86
2.76
1.66
8.7
2.4
—
—
—
0
0
26
229
+∞
1.04
58.0
9.2
90.6
73.2
umol/l
1.46
26
229
13
83
2.13
1.00
4.0
4.0
—
—
—
0
0
5
27
2.05
0.73
5.2
2.3
226.0
694.6
ng/l
—
5
21
6
34
1.99
0.64
2.7
1.6
276.5
13034.0
umol/l
—
6
28
0
22
0.00
0.62
0.0
1.5
—
—
—
0
0
7
48
1.62
0.52
1.7
1.6
—
—
—
0
0
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
0
15
0.00
0.43
0.0
1.3
—
—
—
0
0
0
17
0.00
0.42
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
3.8
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
21
209
1.02
0.00
7.9
3.2
1.1
1.2
mmol/l
0.61
21
192
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
19
191
0.98
0.00
4.3
3.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: E4_APECED – APECED
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).