Anemia, Hemolytic, Autoimmune: Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder in which various types of auto-antibodies are directed against red blood cells causing their survival to be shortened and resulting in hemolytic anemia.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1342 |
4. Check minimum number of eventsNone |
1342 |
5. Include endpointsNone |
1342 |
6. Filter based on genotype QC (FinnGen only) |
1342 |
Control definitions (FinnGen only)
- Control exclude
- D3_APLASTICANDOTHANAEMIA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D60-D64
- Name in latin
- Anaemia posthaemorrhagica acuta
Similar endpoints
↥List of similar endpoints to
Acute posthaemorrhagic anaemia
based on the number of shared cases.
Similar with more cases:
- Aplastic and other anaemias
- Anaemias
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 15654 | 8391 | 7003 |
| Only index persons | 10414 | 5848 | 4566 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.22 | 0.24 | 0.20 |
| Only index persons | 0.20 | 0.21 | 0.17 |
| Median age at first event (years) | |||
| Whole population | 73.23 | 75.42 | 70.61 |
| Only index persons | 71.10 | 72.75 | 68.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1342 | 632 | 710 |
| Unadjusted period prevalence (%) | 0.27 | 0.22 | 0.31 |
| Median age at first event (years) | 68.11 | 64.57 | 71.27 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1224
- Matched controls
- 12239
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
16384.0
323.0
1116
5
D64.9
ICD-10 Finland
Anaemia, unspecified
34.9
323.0
439
193
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.8
169.8
673
2130
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
18.2
129.3
207
135
2851A
ICD-9 Finland
Other and unspecified anaemias, Acute posthaemorrhagic anaemia
+∞
114.4
108
*
K92.1
ICD-10 Finland
Melaena
8.7
112.9
263
371
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
8.7
112.0
261
368
WW500
NOMESCO Finland
Blood transfusion
13.3
93.4
170
147
C03CA01
ATC
furosemide; systemic
3.0
73.0
656
3369
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
11.3
71.2
139
137
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.3
67.2
288
822
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.8
66.8
339
1125
UJF32
NOMESCO Finland
Coloscopy
3.1
61.9
451
1949
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
55.6
356
1383
TPH04
NOMESCO Finland
Cathetrisation of vein
3.0
50.2
368
1551
I50.9
ICD-10 Finland
Heart failure, unspecified
2.9
47.9
354
1496
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
44.5
625
3745
A02BC02
ATC
pantoprazole; systemic
2.4
44.2
845
5894
K92.0
ICD-10 Finland
Haematemesis
8.0
43.1
101
136
WX892
NOMESCO Finland
Monitored bed care
4.3
40.7
164
427
TPH07
NOMESCO Finland
Cathetrisation of artery
3.5
39.6
206
668
UJF92
NOMESCO Finland
Capsular endoscopy
14.9
38.6
65
46
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
11.5
38.0
72
66
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
37.1
228
833
B01AA03
ATC
warfarin; systemic
2.4
36.9
431
2296
JN3AD
NOMESCO Finland
Abdominal CT examination
4.0
35.5
153
422
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.4
34.9
135
336
C03DA01
ATC
spironolactone; oral
3.0
34.1
228
878
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
9.7
33.9
70
76
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.8
33.5
154
449
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.2
33.4
443
2480
M04AA01
ATC
allopurinol; systemic
2.7
32.6
257
1095
K55.8
ICD-10 Finland
Other vascular disorders of intestine
40.2
31.3
39
10
AA1AD
NOMESCO Finland
CT of head and brain
2.3
31.1
370
1954
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
31.0
180
628
B01AB05
ATC
enoxaparin; parenteral
2.2
30.3
420
2376
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.2
30.2
120
306
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.2
30.0
177
621
TK800
NOMESCO Finland
Hemodialysis
8.5
29.8
66
81
ZX120
NOMESCO Finland
Intravenous
3.2
29.6
169
579
3AC01
NOMESCO Finland
NA
16.4
28.7
46
29
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
10.4
28.4
56
56
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
27.9
347
1854
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.7
27.7
65
88
WX872
NOMESCO Finland
Intensive care
4.2
27.5
110
282
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
4.0
27.3
114
304
B03XA02
ATC
darbepoetin alfa; parenteral
9.3
27.2
57
64
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
27.2
416
2428
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
26.8
138
439
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
26.7
182
704
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.7
26.4
120
345
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
26.3
279
1376
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
26.3
279
1378
A11CC03
ATC
alfacalcidol; systemic
7.5
26.0
62
86
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.3
25.7
100
250
I50.0
ICD-10 Finland
Congestive heart failure
2.7
25.5
189
768
UJD02
NOMESCO Finland
Gastroscopy
3.9
25.2
108
295
WX882
NOMESCO Finland
High dependency care
5.9
25.1
72
129
UJF02
NOMESCO Finland
Peroral enteroscopy
26.8
24.9
34
13
B82
ICPC
Anaemia other/unspecified
7.2
24.1
59
85
JN4BD
NOMESCO Finland
Extensive body CT
2.7
24.1
179
724
N02AX02
ATC
tramadol; systemic, rectal
1.9
24.0
541
3618
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
11.1
23.7
45
42
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
17.3
23.6
37
22
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
6.9
23.4
59
89
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.8
23.4
104
293
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
23.0
222
1040
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.3
23.0
237
1145
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
23.0
293
1562
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
8.5
22.8
50
61
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.1
22.5
327
1844
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.0
22.5
398
2423
C07AB07
ATC
bisoprolol; oral
1.8
22.3
662
4816
UJF30
NOMESCO Finland
Ileoscopy through colon
3.1
21.8
129
452
PG1PT
NOMESCO Finland
Extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
19.3
21.3
32
17
127
Kela drug reimbursment
Transplant complication
11.8
21.3
39
34
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
21.1
131
474
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
20.8
232
1161
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.4
20.8
77
184
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
20.7
417
2640
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.1
20.2
80
204
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
8.2
20.1
45
57
J01MA12
ATC
levofloxacin; systemic
2.1
20.0
269
1457
C01DA14
ATC
isosorbide mononitrate; oral
2.0
19.8
312
1801
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.4
19.5
100
316
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
7.3
19.5
47
67
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
6.8
19.3
49
75
N19
ICD-10 Finland
Unspecified kidney failure
4.0
19.2
79
208
R50.9
ICD-10 Finland
Fever, unspecified
2.3
19.2
193
917
XW000
NOMESCO Finland
Bone marrow biopsy
4.2
19.1
73
180
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
19.1
249
1329
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.9
19.0
346
2102
A41.9
ICD-10 Finland
Sepsis, unspecified
3.8
18.9
82
227
D64.8
ICD-10 Finland
Other specified anaemias
9.5
18.7
38
41
JDA42
NOMESCO Finland
Other endoscopic haemostatic procedure in stomach or pylorus
19.1
18.7
28
15
JN4AD
NOMESCO Finland
Body CT examination
2.9
18.5
117
428
A06AD11
ATC
lactulose; oral
2.0
18.5
265
1467
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.9
18.5
39
45
TKC20
NOMESCO Finland
Catheterisation of bladder
2.7
18.1
132
526
WX002
NOMESCO Finland
Sedation and analgesia
2.0
17.9
250
1369
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.7
17.7
131
528
A02BC01
ATC
omeprazole; systemic
1.8
17.6
381
2445
A12AA04
ATC
calcium carbonate; oral
7.5
17.5
41
56
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
29.2
17.4
23
8
I25.2
ICD-10 Finland
Old myocardial infarction
2.4
17.3
152
673
F10.25
ICD-10 Finland
Alcohol dependence continuous use
7.1
17.3
42
61
A46
ICD-10 Finland
Erysipelas
2.1
17.1
209
1081
Z94.0
ICD-10 Finland
Kidney transplant status
12.9
16.7
29
23
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.1
16.6
65
164
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.5
16.5
132
554
D50.8
ICD-10 Finland
Other iron deficiency anaemias
7.7
16.5
38
51
N05CF01
ATC
zopiclone; oral
1.7
16.4
438
2988
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
16.3
746
5918
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
13.0
16.2
28
22
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.4
16.1
81
253
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
16.1
211
1120
C01AA05
ATC
digoxin; systemic
2.1
16.1
195
1002
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.7
16.1
55
122
I50.1
ICD-10 Finland
Left ventricular failure
2.7
15.8
112
440
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.9
15.7
65
173
R53
ICD-10 Finland
Malaise and fatigue
1.9
15.7
278
1656
R04.0
ICD-10 Finland
Epistaxis
2.6
15.6
120
493
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
8.7
15.5
33
39
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.8
15.5
330
2090
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.8
15.5
100
372
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.3
15.4
57
137
K22.1
ICD-10 Finland
Ulcer of oesophagus
5.4
15.4
46
88
205
Kela drug reimbursment
Chronic hypertension
1.7
15.4
442
3066
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
15.4
196
1028
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
8.8
15.3
32
37
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
8.2
15.1
33
41
J01MA14
ATC
moxifloxacin; systemic
2.5
15.0
123
524
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
15.0
141
644
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.8
14.9
102
390
R4110
NOMESCO Finland
Physiotherapy
1.8
14.8
308
1933
J01MA02
ATC
ciprofloxacin; systemic
1.7
14.8
488
3506
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
14.8
416
2861
N18.8
ICD-10 Finland
Other chronic renal failure
4.1
14.7
58
148
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
14.7
209
1147
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.2
14.7
77
249
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.7
14.6
377
2527
B01AB10
ATC
tinzaparin; parenteral
2.8
14.4
97
369
A02BC03
ATC
lansoprazole; oral
1.7
14.3
355
2349
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.6
14.1
108
443
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.5
14.0
112
471
J01DB01
ATC
cefalexin; oral
1.7
14.0
884
7481
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.0
14.0
56
145
C09AA05
ATC
ramipril; oral
1.7
13.9
350
2323
R06.0
ICD-10 Finland
Dyspnoea
1.7
13.9
317
2041
L04AA06
ATC
mycophenolic acid; systemic
7.0
13.7
33
48
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.3
13.6
125
566
N02AA05
ATC
oxycodone; systemic
1.9
13.2
208
1181
A10AE04
ATC
insulin glargine; parenteral
2.3
13.2
132
620
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
7.0
13.2
32
47
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.5
13.2
105
439
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.6
13.1
95
377
F10.24
ICD-10 Finland
Alcohol depence active use
8.4
13.1
28
34
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
13.0
163
846
A04
ICPC
Weakness/tiredness general
2.1
13.0
163
847
R18
ICD-10 Finland
Ascites
5.1
12.8
40
81
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
11.7
12.8
23
20
E87.5
ICD-10 Finland
Hyperkalaemia
5.3
12.8
38
73
I50
ICD-10 Finland
Heart failure
3.2
12.7
67
218
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.4
12.7
114
510
JAH00
NOMESCO Finland
Laparotomy
3.8
12.6
53
144
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
5.4
12.6
37
70
B02AA02
ATC
tranexamic acid; systemic
2.1
12.3
155
808
K55.2
ICD-10 Finland
Angiodysplasia of colon
8.5
12.3
26
31
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
9.8
12.3
24
25
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.8
12.2
81
307
C07AB02
ATC
metoprolol; systemic
1.7
12.2
318
2119
PC1CC
NOMESCO Finland
Very extensive angiography of aorta and abdominal arteries
16.0
12.2
19
12
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.8
12.1
76
278
C08CA01
ATC
amlodipine; oral
1.6
12.1
452
3309
S97
ICPC
Chronic ulcer skin
2.7
12.1
86
337
J01FF01
ATC
clindamycin; systemic
1.7
12.1
294
1920
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
27.0
12.1
16
6
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.0
374
2613
V03AE01
ATC
polystyrene sulfonate; oral
6.1
12.0
32
54
B01AC04
ATC
clopidogrel; oral
1.8
11.9
220
1318
JN4CD
NOMESCO Finland
Very extensive body CT
3.0
11.9
68
234
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.7
11.8
79
301
E86
ICD-10 Finland
Volume depletion
3.5
11.7
54
159
M10.9
ICD-10 Finland
Gout, unspecified
2.4
11.7
102
448
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.1
11.7
31
52
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
11.7
107
481
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
16.6
11.7
18
11
B80
ICPC
Iron deficiency anaemia
5.6
11.7
33
60
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.2
11.6
119
564
AN1
HP
Coronary angiography
1.9
11.6
181
1023
JFB00
NOMESCO Finland
Partial resection of small intestine
5.2
11.6
35
69
I20.09
ICD-10 Finland
Unstable angina
2.3
11.5
104
466
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.9
11.5
37
78
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.2
11.5
43
106
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
7.6
11.5
26
35
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
121.1
11.4
12
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
11.4
146
765
A12BA01
ATC
potassium chloride; oral
2.3
11.4
105
474
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
11.4
186
1066
K26.4
ICD-10 Finland
Duodenal ulcer, chronic or unspecified with haemorrhage
11.9
11.3
20
17
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.8
11.3
206
1227
Z49.0
ICD-10 Finland
Preparatory care for dialysis
9.0
11.3
23
26
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
9.0
11.3
23
26
PG1QT
NOMESCO Finland
Very extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
35.4
11.3
14
*
K70.1
ICD-10 Finland
Alcoholic hepatitis
9.7
11.3
22
23
L04AX01
ATC
azathioprine; systemic
3.2
11.2
58
187
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.3
11.2
56
176
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
11.2
213
1288
SPAT1262
SPAT
Handing over of treatment supplies
1.8
11.1
214
1301
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.7
11.1
47
130
N03AX16
ATC
pregabalin; oral
1.7
11.0
257
1652
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
11.0
327
2245
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
11.0
347
2420
K70.4
ICD-10 Finland
Alcoholic hepatic failure
14.0
11.0
18
13
RS221
NOMESCO Finland
NA
6.3
10.9
28
45
R55
ICD-10 Finland
Syncope and collapse
1.9
10.9
156
853
N02BE01
ATC
paracetamol; systemic, rectal
1.6
10.8
961
8500
A07AA09
ATC
vancomycin; oral
5.3
10.8
32
62
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
10.8
131
672
D50
ICD-10 Finland
Iron deficiency anaemia
5.9
10.8
29
50
SPAT1254
SPAT
Administration of medicine
1.8
10.8
200
1199
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.8
10.7
70
261
WX402
NOMESCO Finland
General anaesthesia
1.9
10.6
154
847
N17.8
ICD-10 Finland
Other acute renal failure
5.6
10.6
30
55
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
10.6
112
539
P15
ICPC
Chronic alcohol abuse
4.6
10.5
35
77
PD5BD
NOMESCO Finland
Extensive CT of aorta
4.1
10.5
40
101
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
10.4
341
2395
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.2
10.4
102
477
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
10.4
208
1275
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.0
10.4
59
202
PD1CD
NOMESCO Finland
Very extensive CT of abdominal aorta and branches
16.2
10.4
16
10
K72.9
ICD-10 Finland
Hepatic failure, unspecified
12.2
10.4
18
15
K29.2
ICD-10 Finland
Alcoholic gastritis
32.8
10.3
13
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
5.4
10.3
30
57
SPAT1255
SPAT
Intravenous administration of medicine
2.3
10.3
91
405
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.8
10.3
65
240
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
19.0
10.3
15
8
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.8
10.3
66
247
81
HP
Angiography of the heart and coronary arteries
2.1
10.2
117
586
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.9
10.2
63
227
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.6
10.2
73
291
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.7
10.1
28
50
A28
ICPC
Limited function/disability NOS
1.7
10.1
215
1342
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.2
10.1
106
509
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.9
10.0
40
105
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
10.0
237
1523
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.5
10.0
45
131
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.9
9.9
31
64
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.9
227
1446
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.1
9.9
53
176
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.1
9.8
53
177
R11
ICD-10 Finland
Nausea and vomiting
2.1
9.8
109
537
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.4
9.8
82
354
N05BA04
ATC
oxazepam; oral
1.6
9.8
275
1856
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
9.8
111
554
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
9.7
464
3543
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.5
9.7
16
12
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
10.1
9.5
18
18
V03AE02
ATC
sevelamer; oral
15.2
9.5
15
10
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
15.2
9.5
15
10
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
9.5
476
3675
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.3
9.4
90
415
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.6
9.4
31
68
207
Kela drug reimbursment
Chronic arrhythmias
1.7
9.4
207
1301
K76.7
ICD-10 Finland
Hepatorenal syndrome
30.3
9.4
12
*
A07AA11
ATC
rifaximin; oral
30.3
9.4
12
*
WX725
NOMESCO Finland
Noninvasive ventilation
2.7
9.4
61
230
2859X
ICD-9 Finland
Other and unspecified anaemias, Anaemia, unspecified[ANAEMIA NUD]
+∞
9.4
9
*
WX704
NOMESCO Finland
Intubation
2.3
9.4
85
384
A10AE05
ATC
insulin detemir; parenteral
2.5
9.3
71
293
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.0
9.3
122
645
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.1
9.3
28
56
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
6.5
9.3
23
36
N05BA02
ATC
chlordiazepoxide; systemic
3.8
9.3
38
103
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.8
9.3
38
103
A10BH01
ATC
sitagliptin; oral
2.0
9.2
118
618
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
7.8
9.1
20
26
SPAT1104
SPAT
Monitoring of emergency patient
2.3
9.1
86
396
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.2
9.1
90
420
C07AG02
ATC
carvedilol; oral
2.2
9.0
90
426
JDA35
NOMESCO Finland
Endoscopic contact coagulation in stomach or pylorus
18.7
8.9
13
7
A41.8
ICD-10 Finland
Other specified sepsis
4.0
8.9
34
87
C09AA02
ATC
enalapril; systemic
1.6
8.8
271
1865
PD5AD
NOMESCO Finland
CT of aorta
4.6
8.8
29
64
WX730
NOMESCO Finland
Conventional respirator
4.1
8.8
33
83
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.9
8.8
34
88
H02AB06
ATC
prednisolone; systemic
1.4
8.7
516
4094
PC4SC
NOMESCO Finland
Bowel angiography with X-ray
50.3
8.7
10
*
R31
ICD-10 Finland
Unspecified haematuria
1.9
8.6
138
785
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
8.6
298
2107
137
Kela drug reimbursment
Uraemia requiring dialysis
8.3
8.6
18
22
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.6
8.6
62
249
E87.6
ICD-10 Finland
Hypokalaemia
3.0
8.5
49
170
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.2
8.4
43
139
D64.0
ICD-10 Finland
Hereditary sideroblastic anaemia
+∞
8.3
8
*
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
4.3
8.3
29
68
TK810
NOMESCO Finland
Hemofiltration
9.5
8.3
16
17
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.2
8.3
78
360
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.2
8.2
84
399
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.6
8.2
27
60
D70.89
ICD-10 Finland
Neutropenic splenomegaly
6.5
8.2
20
31
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.8
8.2
33
89
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
5.4
8.2
23
43
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
5.7
8.1
22
39
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
17.3
8.1
12
7
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
8.1
253
1747
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
9.0
8.0
16
18
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.9
8.0
21
36
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.6
8.0
55
215
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.5
8.0
59
241
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.0
7.9
100
522
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
7.9
157
955
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
4.3
7.9
28
67
B03XA01
ATC
erythropoietin; parenteral
5.4
7.8
22
41
A10BA02
ATC
metformin; oral
1.5
7.8
329
2421
GD1AD
NOMESCO Finland
Thorax CT examination
2.6
7.8
57
229
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
10.9
7.8
14
13
Z49.2
ICD-10 Finland
Other dialysis
9.5
7.8
15
16
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
7.0
7.8
18
26
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.5
7.7
34
99
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.5
7.7
34
99
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
7.7
148
893
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.2
7.6
78
373
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.7
7.6
50
192
D63.8
ICD-10 Finland
Anaemia in other chronic diseases classified elsewhere
25.2
7.6
10
*
N07BB01
ATC
disulfiram; oral
3.0
7.6
43
148
5781A
ICD-9 Finland
Gastro-intestinal haemorrhage, Melaena[MELAENA]
8.9
7.5
15
17
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
5.5
7.5
21
39
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.7
7.5
48
179
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.1
7.5
86
429
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.5
379
2893
PWE00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of peripheral vessels and lymphatic system
7.2
7.5
17
24
K29.6
ICD-10 Finland
Other gastritis
5.1
7.4
22
44
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
80.5
7.4
8
*
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
7.7
7.4
16
21
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
7.7
7.4
16
21
K86.1
ICD-10 Finland
Other chronic pancreatitis
6.0
7.4
19
32
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.4
330
2459
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.1
7.3
85
429
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.3
7.3
67
306
N06AX11
ATC
mirtazapine; oral
1.5
7.3
314
2319
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
7.3
200
1332
K56.7
ICD-10 Finland
Ileus, unspecified
3.7
7.3
30
83
N05CD07
ATC
temazepam; oral
1.6
7.3
178
1153
L04AD01
ATC
ciclosporin; systemic
4.5
7.3
24
54
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.3
7.3
66
300
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.6
7.3
51
203
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
15.8
7.2
11
7
V03AE03
ATC
lanthanum carbonate; oral
15.8
7.2
11
7
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.0
7.2
93
491
N05BA01
ATC
diazepam; systemic, rectal
1.7
7.2
157
985
J01DA01
ATC
[U] cefalexin; systemic
1.4
7.2
687
5873
JFB30
NOMESCO Finland
Right hemicolectomy
4.0
7.2
27
69
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
3.7
7.2
29
79
A02BC05
ATC
esomeprazole; systemic
1.4
7.2
415
3247
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.9
7.2
42
150
C02EA02
ATC
NA
2.1
7.1
81
406
L28
ICPC
Limited function/disability (L)
1.6
7.1
198
1326
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.9
7.1
27
70
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
6.1
7.1
18
30
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
5.7
7.1
19
34
NF1AA
NOMESCO Finland
Hip X-ray examination
1.8
7.1
112
635
SPAT1088
SPAT
Blood transfusion
8.8
7.1
14
16
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.8
7.0
114
652
R60.0
ICD-10 Finland
Localized oedema
1.8
7.0
131
781
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
1.8
7.0
121
706
N05AH04
ATC
quetiapine; oral
1.7
7.0
144
887
JDA32
NOMESCO Finland
Endoscopic injection in stomach or pylorus
7.0
7.0
16
23
N18.0
ICD-10 Finland
End-stage renal disease
4.5
7.0
23
52
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
4.3
6.9
24
57
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
3.3
6.9
33
103
PD1AD
NOMESCO Finland
CT of abdominal aorta and branches
7.6
6.9
15
20
Z94.4
ICD-10 Finland
Liver transplant status
13.9
6.9
11
8
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
13.9
6.9
11
8
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.4
6.9
31
93
XCK10
NOMESCO Finland
Photography of fundus of eye
1.8
6.8
119
695
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
3.0
6.8
36
121
F10.09
ICD-10 Finland
Alcohol intoxication UNS
3.9
6.8
26
68
L04AA01
ATC
[U] ciclosporin; systemic
4.6
6.8
22
49
F60.9
ICD-10 Finland
Personality disorder, unspecified
5.3
6.8
19
36
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
6.8
47
184
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
6.8
321
2416
I20.01
ICD-10 Finland
Unstable angina
2.5
6.8
49
200
Z72.8
ICD-10 Finland
Other problems related to lifestyle
16.8
6.7
10
6
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.2
6.7
67
317
R10.0
ICD-10 Finland
Acute abdomen
2.9
6.7
39
138
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
2.3
6.7
60
272
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
6.7
111
639
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
4.1
6.7
24
59
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.1
6.7
69
331
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.0
6.7
35
117
WX740
NOMESCO Finland
Nitrogen oxide therapy
22.6
6.7
9
*
X78
ICD-10 Finland
Intentional self-harm by sharp object
22.6
6.7
9
*
R4190
NOMESCO Finland
Nutritional therapy
3.1
6.7
34
112
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
6.5
6.6
16
25
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
6.5
6.6
16
25
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.2
6.6
66
311
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.9
6.6
38
133
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.6
6.6
162
1046
ZZA00
NOMESCO Finland
Split skin graft
2.6
6.6
44
171
S18
ICPC
Laceration/cut
1.4
6.6
419
3320
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
5.5
6.6
18
33
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
5.5
6.6
18
33
XF640
NOMESCO Finland
NA
2.7
6.6
43
164
NB6AA
NOMESCO Finland
Humerus X-ray examination
3.6
6.6
28
80
L03AA02
ATC
filgrastim; parenteral
3.1
6.6
33
107
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
6.6
222
1555
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
3.0
6.6
35
119
R33
ICD-10 Finland
Retention of urine
1.8
6.5
115
676
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
4.4
6.5
22
51
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.1
6.5
70
341
-50
ICPC
Medication/prescr/renewal
2.4
6.5
50
210
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.9
6.5
85
451
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.6
6.5
27
76
U14
ICPC
Kidney symptom/complaint
4.0
6.5
24
61
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
2.3
6.5
56
250
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
3.3
6.5
30
92
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.4
6.5
52
222
C10AA01
ATC
simvastatin; oral
1.4
6.5
521
4300
N03AX14
ATC
levetiracetam; systemic
3.4
6.5
29
87
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.1
6.4
70
347
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
4.7
6.4
20
43
B01AB04
ATC
dalteparin; parenteral
2.1
6.4
65
312
I78.0
ICD-10 Finland
Hereditary haemorrhagic telangiectasia
14.4
6.4
10
7
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
2.0
6.4
76
390
R4120
NOMESCO Finland
Occupational therapy
2.1
6.4
65
313
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
3.0
6.4
34
116
C08DB01
ATC
diltiazem; oral
1.9
6.3
95
528
196
Kela drug reimbursment
Paricalcitol and cinacalcet
8.2
6.3
13
16
ZX112
NOMESCO Finland
Subcutaneous
3.2
6.3
30
94
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.7
6.3
41
156
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
6.0
6.3
16
27
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
11.1
6.3
11
10
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.9
6.3
89
485
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
9.3
6.3
12
13
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.4
6.3
51
221
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
6.3
6
*
SPAT1263
SPAT
Sampling
1.4
6.2
422
3378
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
4.3
6.2
21
49
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
4.3
6.2
21
49
K72.1
ICD-10 Finland
Chronic hepatic failure
26.8
6.2
8
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.0
6.2
77
401
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
7.1
6.2
14
20
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
4.0
6.2
23
59
SPAT1234
SPAT
Support of social functional capacity
2.0
6.2
72
364
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
2.5
6.2
47
196
K78
ICPC
Atrial fibrillation/flutter
1.7
6.2
113
672
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
6.1
68
340
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
7.7
6.1
13
17
S70.0
ICD-10 Finland
Contusion of hip
2.3
6.1
55
248
C02AC05
ATC
moxonidine; oral
2.2
6.1
58
271
T90
ICPC
Diabetes non-insulin dependent
1.5
6.1
240
1733
Z53.0
ICD-10 Finland
Procedure not carried out because of contraindication
12.6
6.1
10
8
G72.8
ICD-10 Finland
Other specified myopathies
3.5
6.0
26
76
WX400
NOMESCO Finland
Inhalation anesthesy
2.5
6.0
44
181
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
368
1097
4.24
110.77
3.2
2.2
2.2
1.7
%
7.65
310
952
412
1362
3.92
106.85
4.5
2.1
2.3
2.3
g/l
0.02
384
1241
605
2583
3.44
105.53
4.0
2.0
3.7
3.0
mg/l
7.09
535
2136
437
1515
3.79
105.53
4.6
2.1
9.5
12.6
umol/l
18.66
404
1378
394
1274
3.96
105.33
4.9
2.2
18.1
22.5
%
7.20
331
1067
199
382
5.94
101.34
2.0
1.9
1.4
1.5
g/l
0.60
163
325
289
850
4.06
86.91
12.0
6.0
13.1
10.8
mmol/l
3.82
267
804
324
1052
3.74
84.29
4.2
3.8
260.7
247.9
u/l
0.49
295
985
141
245
6.31
79.04
3.5
2.3
3.4
3.6
g/l
0.69
133
236
399
1538
3.27
78.61
5.1
2.9
0.8
0.8
mmol/l
2.01
371
1419
349
1289
3.31
73.24
11.4
4.7
1.1
1.0
mmol/l
4.51
323
1174
116
203
6.16
64.32
1.7
1.7
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
158
375
4.64
62.14
4.0
2.4
0.3
0.4
u/ml
1.00
98
217
375
1571
2.92
62.04
3.7
1.8
31.0
29.9
s
1.41
359
1521
683
3931
2.50
58.63
5.5
2.5
167.3
134.2
ug/l
1.71
626
3547
481
2378
2.59
56.76
4.8
2.3
—
—
—
0
0
253
889
3.27
56.43
3.3
2.2
0.2
0.2
g/l
4.74
224
827
733
4508
2.38
52.24
7.9
4.0
—
—
—
0
0
295
1199
2.87
50.55
9.2
7.5
0.7
1.3
mmol/l
1.42
231
927
293
1200
2.84
49.39
9.2
7.4
11.9
11.7
kpa
0.21
270
1135
293
1200
2.84
49.39
9.3
7.5
4.9
5.1
kpa
1.57
268
1135
709
4395
2.30
48.31
10.3
4.4
32.2
34.9
g/l
22.78
658
4047
211
746
3.17
46.04
2.1
1.6
—
—
—
0
0
100
211
5.04
45.04
5.6
2.5
40.0
33.3
umol/l
1.41
83
172
150
449
3.64
42.54
7.3
3.4
23.9
24.1
mmol/l
0.31
137
406
240
952
2.85
42.48
7.0
3.1
1.3
2.1
mmol/l
2.62
188
744
332
1563
2.49
41.57
35.3
29.3
1.6
1.4
inr
0.52
23
187
238
953
2.82
41.31
7.1
3.1
5.7
5.8
kpa
0.84
223
921
770
5161
2.15
40.51
11.4
5.7
13.2
12.1
umol/l
0.98
733
4864
100
235
4.52
39.48
4.5
2.0
215.4
193.9
%
1.15
95
220
703
4602
2.11
38.72
12.9
5.6
1.2
1.2
mmol/l
8.20
648
4108
410
2183
2.26
38.34
2.2
1.8
1185.6
1178.7
nmol/l
0.05
330
1595
224
907
2.76
37.86
8.5
6.7
1.5
1.4
mmol/l
0.70
209
869
235
977
2.70
37.72
10.2
8.4
106.2
121.7
g/l
22.53
226
939
75
148
5.31
36.38
6.7
6.0
504.5
1352.9
iu/ml
0.37
19
19
746
5067
2.06
36.33
14.7
6.2
1.2
1.2
mmol/l
8.38
634
4224
155
532
3.16
35.18
11.4
10.7
—
—
—
0
0
515
3088
2.08
34.91
4.8
2.4
55.4
57.5
u/l
0.66
493
2834
277
1305
2.41
33.94
10.6
6.7
104.3
104.2
mmol/l
0.11
272
1268
134
437
3.30
33.05
2.4
1.7
2.3
1.3
ug/l
0.47
117
370
228
998
2.55
32.66
3.4
2.4
8.7
6.7
ug/l
0.38
189
842
660
4413
1.98
32.21
10.1
5.5
22.7
26.7
%
15.12
611
4060
239
1088
2.46
31.40
4.9
2.6
9.1
9.4
umol/l
0.09
206
946
343
1844
2.16
30.28
2.5
1.8
—
—
—
0
0
63
126
5.20
30.08
7.5
6.9
12.5
12.4
mg/l
0.03
56
114
117
384
3.24
28.48
3.1
2.1
582.6
550.4
ug/l
0.05
111
361
163
662
2.66
26.97
9.6
7.1
24.4
24.6
mmol/l
0.34
150
620
142
546
2.79
26.10
10.0
9.6
23.6
24.5
mmol/l
2.06
128
503
358
2052
2.02
26.09
2.6
1.6
1.6
1.3
mg/l
0.77
276
1583
184
806
2.49
26.00
5.4
2.5
4.6
4.4
kpa
0.59
170
779
186
825
2.46
25.57
3.1
2.8
65.3
66.4
g/l
0.96
160
740
178
779
2.48
25.17
7.6
3.3
162.4
86.2
ng/l
7.07
151
677
156
642
2.62
25.08
10.4
9.2
93.7
93.9
%
0.15
156
636
102
335
3.21
24.76
1.4
1.2
—
—
—
0
0
140
555
2.70
24.22
8.5
7.5
24.4
25.0
mmol/l
1.10
140
550
737
5420
1.80
23.99
14.6
7.9
4.5
4.2
e9/l
1.86
678
4707
456
2916
1.85
23.52
5.3
3.1
39.1
34.0
u/l
0.89
424
2780
244
1282
2.10
22.18
2.3
1.7
—
—
—
0
0
782
5930
1.76
22.16
10.1
4.6
7.4
6.8
mmol/l
5.93
743
5545
243
1277
2.10
22.07
2.3
1.7
—
—
—
0
0
28
34
8.39
21.43
3.5
1.4
51.8
71.4
mg/l
1.15
20
25
467
3110
1.77
20.44
3.0
2.1
187.2
238.2
u/l
0.84
435
2902
52
123
4.36
20.32
1.8
1.3
112.4
111.9
u/ml
0.01
11
22
142
618
2.45
20.19
7.5
3.7
1.7
2.0
mmol/l
0.32
108
461
84
279
3.15
20.00
2.1
1.5
—
—
—
0
0
88
304
3.03
19.59
3.8
3.6
49.9
48.1
mg/l
0.05
65
254
88
304
3.03
19.59
3.8
3.6
78.0
73.8
mg/l
0.06
65
253
145
652
2.37
19.15
7.6
3.7
5.2
5.2
kpa
0.15
133
601
177
874
2.18
18.70
5.3
2.4
29.6
34.8
u/l
1.46
148
735
193
988
2.11
18.58
4.1
3.0
388.6
228.0
ng/l
2.91
184
903
65
194
3.47
18.37
2.0
1.6
—
—
—
0
0
140
632
2.36
18.31
3.4
2.7
10.9
10.9
g/l
0.04
127
567
327
2019
1.82
18.12
6.6
4.0
628.6
372.9
ng/l
0.60
293
1678
69
219
3.27
17.71
11.2
8.4
106.0
105.0
mmol/l
0.77
60
198
136
631
2.29
16.66
1.9
1.4
—
—
—
0
0
199
1072
2.01
16.60
3.1
3.8
7.6
22.6
ug/l
1.17
163
886
17
15
11.47
16.23
1.2
1.3
—
—
—
0
0
579
4294
1.61
15.80
2.7
2.0
90.0
92.7
pmol/l
0.74
339
2162
480
3400
1.64
15.78
4.9
3.0
2879.2
1755.1
ng/l
4.47
421
2936
30
55
5.56
15.76
2.9
2.0
—
—
—
0
0
69
236
3.03
15.64
1.8
1.6
—
—
—
0
0
66
225
3.03
15.05
1.9
1.6
—
—
—
0
0
377
2538
1.68
14.97
2.0
1.5
19.1
20.3
nmol/l
0.73
333
2126
345
2270
1.70
14.93
4.4
2.5
5.8
5.3
e6/l
0.30
316
1991
516
3762
1.60
14.87
5.5
3.2
—
—
—
0
0
135
655
2.18
14.81
5.1
2.8
109.5
128.1
g/l
12.97
130
640
552
4118
1.58
14.26
7.5
3.9
62.0
59.4
ng/l
0.07
439
3039
47
137
3.52
13.81
1.4
1.1
324.5
308.4
u/ml
0.11
37
78
54
173
3.21
13.68
1.9
1.7
—
—
—
0
0
899
7536
1.58
13.59
15.5
7.0
89.2
79.6
u/l
6.01
859
6989
68
251
2.80
13.46
1.7
1.2
—
—
—
0
0
68
251
2.80
13.46
1.7
1.2
—
—
—
0
0
48
145
3.40
13.36
1.4
1.1
—
—
—
0
0
366
2512
1.63
13.21
4.6
2.7
2459.6
8665.6
umol/l
2.00
311
2113
477
3497
1.56
12.99
5.2
3.2
2.3
2.4
mmol/l
4.32
412
2977
813
6706
1.54
12.82
7.6
4.8
169.7
2183.4
e6/l
1.85
20
125
87
372
2.43
12.82
3.3
2.5
7.5
7.5
g/l
0.01
58
279
150
800
1.99
12.76
2.9
2.0
388.1
375.3
nmol/l
0.33
140
722
135
697
2.04
12.57
2.2
1.6
—
—
—
0
0
82
346
2.46
12.44
3.4
2.6
3.4
3.2
g/l
0.69
55
274
86
371
2.41
12.43
3.3
2.5
4.2
3.8
g/l
0.59
55
269
34
85
4.08
12.42
1.7
1.1
70.3
53.0
u/l
0.96
23
58
336
2292
1.62
12.31
2.0
1.7
42806193.7
10276254.4
pmol/l
0.34
278
1849
61
226
2.78
12.01
1.4
1.5
—
—
—
0
0
41
120
3.49
12.00
1.7
1.5
—
—
—
0
0
85
372
2.37
11.90
3.3
2.5
—
—
—
0
0
16
20
8.08
11.90
1.3
1.1
84.3
91.9
%
—
8
11
41
121
3.46
11.85
2.7
1.7
30.7
32.7
pg
1.32
41
121
46
148
3.18
11.61
6.3
3.5
1.9
1.6
%
0.21
33
116
44
138
3.26
11.57
1.9
1.6
—
—
—
0
0
93
429
2.25
11.54
9.3
5.6
1.8
1.7
%
0.58
83
404
76
321
2.45
11.51
3.2
2.9
0.8
1.4
g/l
0.67
57
275
89
405
2.28
11.40
9.0
4.1
24.5
25.0
mmol/l
0.65
82
377
28
65
4.38
11.26
1.5
1.2
—
—
—
0
0
31
79
3.99
11.05
1.6
1.7
—
—
—
0
0
80
353
2.35
11.01
3.2
2.5
10.7
10.7
g/l
0.01
59
298
514
3936
1.50
10.97
3.2
2.2
75.5
78.1
nmol/l
1.34
448
3421
25
55
4.61
10.73
2.5
1.5
6.1
6.6
u/l
0.05
15
25
43
140
3.14
10.66
1.7
1.4
—
—
—
0
0
38
115
3.37
10.59
3.9
2.4
—
—
—
0
0
15
20
7.57
10.57
1.5
1.2
76.0
94.8
%
—
7
11
53
196
2.77
10.50
4.3
2.4
14.7
16.2
%
1.76
27
99
27
65
4.22
10.38
1.6
1.2
—
—
—
0
0
395
2892
1.52
10.34
5.3
3.1
0.5
0.5
e6/l
0.33
336
2231
42
138
3.11
10.26
1.8
1.2
—
—
—
0
0
80
365
2.27
10.20
3.0
2.9
—
—
—
0
0
153
883
1.83
10.20
2.5
1.7
1.9
1.5
%
2.67
125
758
46
160
2.94
10.19
1.7
1.5
—
—
—
0
0
36
108
3.40
10.18
1.9
1.6
—
—
—
0
0
64
265
2.49
10.14
4.8
3.2
25.1
25.3
mmol/l
0.08
57
230
58
229
2.60
10.13
7.1
4.3
5.0
5.1
kpa
0.31
58
224
21
42
5.06
10.06
1.3
1.5
—
—
—
0
0
21
42
5.06
10.06
1.3
1.5
—
—
—
0
0
68
297
2.36
9.60
4.0
3.1
1.0
0.9
nmol/l
0.59
44
231
179
1104
1.72
9.49
5.8
3.3
—
—
—
0
0
21
45
4.72
9.31
1.8
1.3
—
—
—
0
0
53
210
2.59
9.21
1.5
1.3
—
—
—
0
0
53
214
2.54
8.88
3.5
2.1
111.1
131.3
g/l
3.82
39
151
101
534
1.96
8.80
5.8
2.8
24.6
25.2
mmol/l
1.17
96
515
21
48
4.43
8.63
2.1
1.5
—
—
—
0
0
21
48
4.43
8.63
2.1
1.5
—
—
—
0
0
63
282
2.29
8.44
3.5
2.7
0.5
0.0
g/l
0.47
53
258
21
49
4.34
8.42
1.7
1.1
—
—
—
0
0
21
49
4.34
8.42
1.7
1.1
—
—
—
0
0
38
133
2.91
8.37
1.7
1.4
—
—
—
0
0
10
11
9.15
8.09
17.0
11.0
5.3
6.5
mmol/l
—
10
11
13
20
6.55
8.07
1.2
1.4
—
—
—
0
0
59
262
2.31
8.06
3.2
2.8
0.0
0.0
g/l
0.00
50
242
39
142
2.80
8.01
1.1
1.3
1583.3
1322.6
e6/l
0.26
28
101
42
160
2.68
7.93
3.6
3.2
4.3
4.4
e9/l
0.06
42
160
59
265
2.28
7.86
3.2
2.8
0.0
0.0
g/l
0.49
50
243
65
306
2.18
7.74
3.1
2.6
35.1
37.0
g/l
1.39
51
257
26
76
3.47
7.69
2.1
1.6
—
—
—
0
0
685
5777
1.38
7.67
5.8
3.0
85.5
51.8
u/l
5.38
621
5296
42
163
2.63
7.65
4.7
3.4
61.9
58.9
%
0.81
42
163
36
129
2.84
7.63
1.1
1.3
251478.4
110851.0
e6/l
0.31
23
79
11
15
7.39
7.56
1.0
1.1
—
—
—
0
0
22
58
3.84
7.54
2.1
1.4
—
—
—
0
0
68
331
2.11
7.45
5.9
3.7
3.9
3.9
mmol/l
0.26
61
304
11
16
6.92
7.15
2.4
1.7
—
—
—
0
0
85
462
1.90
6.87
2.7
1.9
—
—
—
0
0
16
37
4.36
6.50
2.1
4.0
140.6
95.4
umol/l
—
10
25
30
107
2.84
6.44
1.8
1.8
—
—
—
0
0
33
124
2.70
6.44
4.3
4.1
337.7
357.3
umol/l
0.29
25
108
23
71
3.28
6.29
1.3
1.1
120.0
95.0
titre
—
6
12
9
5
18.11
6.27
8.8
8.0
—
—
—
0
0
78
426
1.88
6.23
2.4
1.7
—
—
—
0
0
21
62
3.43
6.15
1.8
1.5
1.6
1.2
promille
0.55
14
51
47
214
2.24
6.12
1.6
1.3
—
—
—
0
0
11
19
5.83
6.11
3.4
3.1
13.5
15.2
ml/dl
0.90
11
14
18
48
3.79
6.10
1.1
1.1
—
—
—
0
0
34
135
2.56
5.98
1.7
1.3
—
—
—
0
0
16
40
4.04
5.90
2.3
2.0
—
—
—
0
0
34
136
2.54
5.89
1.7
1.3
—
—
—
0
0
72
391
1.89
5.87
3.2
3.2
2287.3
10095.4
u/ml
0.55
54
335
229
1664
1.45
5.87
4.2
3.0
2.2
2.4
e6/l
0.22
142
945
30
113
2.69
5.85
1.3
1.2
2.5
2.3
u/ml
0.10
12
32
34
137
2.52
5.81
1.7
1.3
—
—
—
0
0
21
65
3.27
5.74
2.4
2.6
—
—
—
0
0
16
41
3.94
5.72
1.6
1.7
—
—
—
0
0
16
41
3.94
5.72
1.6
1.7
—
—
—
0
0
16
41
3.94
5.72
1.0
1.0
—
—
—
0
0
378
3007
1.36
5.70
4.1
3.0
6.3
7.4
mmol/l
6.20
305
2474
33
133
2.52
5.64
1.7
1.3
—
—
—
0
0
33
133
2.52
5.64
1.7
1.3
—
—
—
0
0
57
291
2.00
5.57
1.4
1.4
209.3
288.2
ug/g
2.42
39
174
33
134
2.50
5.56
1.7
1.3
—
—
—
0
0
16
42
3.84
5.54
1.6
1.7
—
—
—
0
0
8
5
16.09
5.41
1.6
2.0
—
—
—
0
0
237
1760
1.42
5.37
4.1
2.8
1.1
1.1
e6/l
0.15
152
1035
27
101
2.71
5.35
1.6
1.8
—
—
—
0
0
9
8
11.32
5.29
2.3
1.0
—
—
—
0
0
42
198
2.16
5.08
2.1
3.4
34.6
303.2
u/ml
1.34
37
183
30
122
2.49
5.06
12.8
6.1
8.1
7.3
mmol/l
0.62
25
101
792
7077
1.29
4.90
5.7
4.0
20.5
13.3
mm/h
15.90
718
6466
37
171
2.20
4.71
2.8
2.1
2374.2
1880.7
u/l
0.08
18
66
29
121
2.43
4.66
1.3
1.2
3.7
7.2
u/ml
0.69
13
54
25
97
2.61
4.65
5.8
3.0
55.1
53.6
%
0.11
14
68
238
1813
1.38
4.62
1.3
1.2
2.8
1.8
u/ml
0.23
52
469
17
54
3.18
4.49
1.6
1.6
—
—
—
0
0
17
54
3.18
4.49
1.6
1.6
—
—
—
0
0
17
54
3.18
4.49
1.6
1.6
—
—
—
0
0
17
54
3.18
4.49
1.6
1.6
—
—
—
0
0
78
473
1.69
4.46
3.7
3.2
4.1
4.5
pmol/l
2.08
68
410
30
132
2.30
4.31
2.0
2.2
26.5
27.6
mg/l
0.03
11
37
375
3087
1.30
4.27
4.5
3.8
18.1
8.5
mg/mmol
2.05
255
1950
23
92
2.53
4.06
1.5
1.6
—
—
—
0
0
23
92
2.53
4.06
1.5
1.6
—
—
—
0
0
23
92
2.53
4.06
1.5
1.6
—
—
—
0
0
51
282
1.84
4.02
1.3
1.2
—
—
—
0
0
51
282
1.84
4.02
1.4
1.2
—
—
—
0
0
47
255
1.87
3.93
1.6
2.0
—
—
—
0
0
27
561
0.47
3.84
1.6
1.8
—
—
—
0
0
259
2058
1.32
3.78
4.1
3.0
2.5
2.5
mmol/l
1.88
220
1783
29
134
2.19
3.75
1.2
1.1
—
—
—
0
0
14
45
3.13
3.65
1.8
1.2
—
—
—
0
0
191
2435
0.75
3.39
1.9
1.6
1.5
1.3
mmol/l
1.04
163
2014
8
14
5.74
3.34
1.4
2.1
13.0
14.5
umol/l
—
8
14
6
7
8.60
3.26
1.0
1.0
—
—
—
0
0
32
164
1.97
3.21
1.2
1.2
—
2.1
—
0
11
11
33
3.35
3.19
1.3
1.7
7.2
8.1
mmol/l
0.42
11
19
18
76
2.39
2.90
1.1
1.1
—
—
—
0
0
7
13
5.41
2.87
1.4
1.1
50.2
261.1
ng/l
—
7
8
17
71
2.41
2.80
1.2
1.2
—
—
titre
—
0
0
41
242
1.72
2.69
2.0
1.7
19915.6
17271.4
e6/l
0.11
28
174
113
841
1.38
2.57
6.6
3.2
1.2
1.2
mmol/l
1.25
104
712
5
7
7.17
2.55
1.4
1.0
—
—
—
0
0
6
11
5.47
2.54
5.2
5.2
—
—
—
0
0
9
27
3.35
2.39
1.4
1.2
—
—
—
0
0
11
40
2.76
2.37
2.9
2.7
3469.5
958.1
u/ml
1.00
11
40
174
2126
0.79
2.20
2.8
3.2
0.9
0.8
ug/l
0.29
134
1497
13
54
2.42
2.20
3.7
2.4
—
—
—
0
0
999
9518
1.19
2.14
42.0
15.3
26.6
26.4
mg/l
0.07
926
7653
10
37
2.72
2.10
1.3
1.5
—
—
—
0
0
14
62
2.27
2.08
2.9
1.5
0.9
1.0
g/l
0.99
14
62
31
184
1.70
2.05
1.2
1.3
261.5
224.6
miu/ml
—
10
92
6
15
4.01
2.04
1.0
1.3
46.5
53.3
umol/l
—
6
15
21
111
1.91
2.01
3.9
3.6
—
—
—
0
0
10
38
2.64
2.01
1.1
1.0
—
—
—
0
0
7
21
3.35
1.96
1.7
2.8
—
—
—
0
0
42
274
1.55
1.94
1.4
1.4
—
—
—
0
0
19
99
1.93
1.90
1.4
1.3
5.8
7.4
mmol/l
4.67
14
67
7
22
3.19
1.88
1.7
2.7
—
—
—
0
0
6
17
3.54
1.84
1.5
1.4
—
—
—
0
0
5
12
4.18
1.82
1.0
1.1
—
—
—
0
0
5
12
4.18
1.82
1.0
1.1
—
—
—
0
0
260
2984
0.84
1.76
4.2
4.7
23.8
21.8
%
0.92
117
1550
12
54
2.23
1.74
5.0
4.1
—
—
—
0
0
301
2644
1.18
1.72
6.1
4.2
0.0
0.0
estimate
0.88
110
854
13
61
2.14
1.72
1.6
1.1
—
—
—
0
0
5
13
3.86
1.71
1.2
1.0
—
—
—
0
0
10
42
2.39
1.68
6.8
3.9
223.9
205.0
u/l
—
10
42
7
25
2.81
1.65
1.0
1.0
2423.1
1819.1
miu/ml
—
7
25
856
8977
0.87
1.64
4.7
4.4
1.4
1.5
mmol/l
7.80
765
8081
37
246
1.52
1.61
2.5
2.3
103.7
93.0
ug/min
0.10
25
151
85
1088
0.77
1.60
1.6
1.4
—
—
—
0
0
38
255
1.50
1.59
1.4
1.6
0.3
23.6
iu/ml
0.49
17
51
57
414
1.39
1.59
1.4
1.3
—
—
—
0
0
12
57
2.12
1.55
1.2
1.1
—
—
—
0
0
12
57
2.12
1.55
1.2
1.1
—
—
—
0
0
19
107
1.79
1.55
1.3
1.1
—
—
—
0
0
246
2146
1.18
1.53
6.4
4.4
1.0
1.0
kg/l
0.00
45
304
19
108
1.77
1.51
1.6
1.4
—
—
—
0
0
12
58
2.08
1.49
1.2
1.1
—
—
—
0
0
12
58
2.08
1.49
1.2
1.1
—
—
—
0
0
12
58
2.08
1.49
1.2
1.1
—
—
—
0
0
9
37
2.44
1.48
1.4
1.1
—
71.2
%
—
0
5
892
9301
0.88
1.46
5.1
5.1
2.3
2.6
mmol/l
19.50
790
8397
516
4773
1.13
1.42
5.5
3.8
0.0
0.0
estimate
0.00
116
890
16
88
1.83
1.41
1.6
1.6
—
—
—
0
0
869
9059
0.88
1.36
4.7
4.5
4.2
4.5
mmol/l
18.92
781
8221
14
75
1.88
1.34
1.2
1.2
—
—
—
0
0
9
44
2.05
1.27
1.4
1.3
—
—
—
0
0
519
4829
1.12
1.27
5.6
3.9
0.0
0.0
estimate
0.80
112
878
9
45
2.01
1.23
2.1
2.1
395.4
498.6
e6/l
—
9
40
747
7112
1.11
1.18
4.4
3.8
15.0
14.9
pmol/l
0.32
664
6330
143
1229
1.18
1.10
4.6
4.5
34.4
32.9
%
0.78
106
782
510
4772
1.11
1.10
7.2
5.2
0.0
0.0
estimate
0.00
112
888
7
136
0.51
1.10
2.1
2.0
212.0
202.3
pmol/l
—
7
127
42
557
0.75
1.08
1.8
1.8
—
—
—
0
0
11
59
1.87
1.07
1.0
1.4
2.8
3.3
ug/l
0.19
11
51
5
23
2.18
0.98
2.4
2.1
—
—
—
0
0
0
30
0.00
0.97
0.0
1.2
—
—
—
0
0
7
36
1.95
0.97
2.1
2.5
—
—
—
0
0
7
36
1.95
0.97
2.1
2.5
—
—
—
0
0
863
8334
1.10
0.93
45.7
16.5
35.0
38.9
%
19.09
529
5442
12
70
1.72
0.92
1.2
1.3
—
75.0
—
0
8
28
201
1.40
0.91
1.6
1.7
5.4
5.9
iu/l
—
8
62
62
501
1.25
0.91
1.2
1.2
244.1
267.4
u/ml
0.07
54
455
16
103
1.56
0.87
1.9
1.4
139994.5
179576.0
e6/l
0.09
11
72
6
30
2.00
0.87
1.3
1.5
14.0
8.8
ug/l
—
6
30
49
613
0.79
0.86
1.9
1.9
—
—
—
0
0
35
265
1.33
0.85
1.6
1.7
—
—
—
0
0
395
3709
1.09
0.77
6.0
4.1
—
—
—
0
0
7
39
1.80
0.72
1.9
1.3
—
—
—
0
0
20
142
1.41
0.72
1.3
1.5
—
—
—
0
0
107
1219
0.87
0.72
1.3
1.4
—
—
—
0
0
7
41
1.71
0.70
1.3
1.1
—
—
—
0
0
843
8669
0.93
0.69
4.4
4.0
1.3
1.3
mmol/l
0.92
752
7736
88
761
1.17
0.69
3.4
2.8
52.3
62.6
ml/min/173m2
1.52
53
328
5
27
1.85
0.68
1.2
1.1
—
—
—
0
0
5
27
1.85
0.68
1.2
1.1
—
—
—
0
0
894
9170
0.92
0.68
5.4
4.7
6.3
6.0
mmol/l
5.58
797
8182
18
127
1.42
0.68
1.6
1.6
—
—
—
0
0
792
7679
1.08
0.67
52.3
18.3
15.0
13.8
%
52.72
777
7490
1011
9904
1.08
0.63
48.9
18.2
138.8
139.6
mmol/l
15.18
977
9593
32
253
1.27
0.61
4.6
3.8
34.3
29.7
mg/l
0.18
20
164
18
130
1.39
0.61
1.1
1.1
—
—
—
0
0
527
5050
1.07
0.60
3.0
2.7
—
—
—
0
0
54
639
0.84
0.60
2.1
2.1
9.8
12.2
nmol/l
0.96
40
554
26
201
1.30
0.59
1.3
1.3
—
—
—
0
0
8
53
1.51
0.58
10.8
3.6
—
—
—
0
0
1012
9926
1.08
0.58
49.3
18.3
4.0
4.0
mmol/l
0.78
975
9603
17
123
1.39
0.58
1.1
1.1
17.5
93.3
iu/ml
—
6
25
9
61
1.48
0.53
1.1
1.2
—
—
—
0
0
9
61
1.48
0.53
1.1
1.2
—
—
—
0
0
6
99
0.60
0.52
1.5
1.5
—
—
—
0
0
9
134
0.67
0.52
1.6
1.4
—
—
—
0
0
9
134
0.67
0.52
1.4
1.4
—
—
—
0
0
9
134
0.67
0.52
1.4
1.4
—
—
—
0
0
9
134
0.67
0.52
1.6
1.4
—
—
—
0
0
13
92
1.42
0.50
1.2
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
46
1.52
0.48
1.4
1.2
—
—
—
0
0
20
256
0.78
0.48
1.9
1.6
—
—
—
0
0
858
8747
0.95
0.42
7.6
6.0
41.9
40.4
mmol/mol
3.30
782
7960
10
70
1.43
0.41
1.7
1.2
—
—
—
0
0
28
232
1.21
0.40
1.4
1.2
—
—
—
0
0
45
390
1.16
0.40
1.0
1.0
—
—
—
0
0
19
237
0.80
0.39
1.7
1.7
—
—
—
0
0
5
36
1.39
0.38
1.2
1.9
1.1
6.6
nmol/l
—
5
29
14
107
1.31
0.37
1.0
1.0
—
—
—
0
0
5
37
1.35
0.37
1.2
1.2
—
—
—
0
0
6
43
1.40
0.35
1.2
5.9
—
80.5
—
0
10
6
86
0.70
0.33
1.7
1.5
—
—
—
0
0
6
47
1.28
0.32
1.3
1.1
194.5
526.4
u/l
—
6
42
154
1452
1.07
0.31
1.3
1.2
39.7
37.2
iu/ml
0.09
49
466
27
230
1.18
0.31
1.4
1.5
—
—
—
0
0
130
1385
0.93
0.31
1.3
1.2
5.0
12.8
u/ml
2.24
36
507
10
75
1.34
0.30
1.0
1.0
—
—
—
0
0
873
8606
1.04
0.28
5.4
4.6
2.1
2.1
mu/l
0.10
784
7721
139
1312
1.07
0.28
17.1
8.1
—
—
—
0
0
10
76
1.32
0.28
1.0
1.1
—
—
—
0
0
26
301
0.86
0.28
1.5
1.7
—
—
—
0
0
357
3683
0.96
0.28
4.9
5.4
3.1
4.4
ug/l
0.53
312
3262
18
214
0.84
0.26
2.1
1.4
—
—
—
0
0
1003
9925
1.04
0.26
19.7
10.3
27.1
25.1
u/l
0.61
967
9490
48
528
0.91
0.25
1.1
1.2
73.5
137.5
iu/ml
0.81
18
204
5
40
1.25
0.22
1.4
1.3
—
—
—
0
0
1030
10388
0.96
0.22
61.8
22.3
118.7
133.6
g/l
118.94
1006
10162
28
248
1.13
0.21
4.1
3.0
8.0
7.9
mmol/l
0.06
28
243
0
10
0.00
0.21
0.0
1.4
—
21.3
—
0
5
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
12
98
1.23
0.21
1.7
2.3
0.8
1.8
u/field
—
6
29
15
126
1.19
0.21
1.7
1.7
—
—
—
0
0
1030
10384
0.97
0.20
61.1
22.2
4.0
4.4
e12/l
85.76
997
10023
1030
10381
0.97
0.19
61.1
22.2
237.6
243.0
e9/l
1.16
1002
10061
45
414
1.09
0.19
3.7
2.9
33.9
66.6
u/ml
1.42
45
397
14
118
1.19
0.19
1.6
1.6
55.9
66.5
%
—
9
79
6
52
1.15
0.19
1.2
1.1
256.8
251.8
mg/l
—
6
46
7
60
1.17
0.17
8.9
2.2
13.4
13.2
%
—
7
60
5
69
0.72
0.17
1.8
2.3
—
82.6
—
0
11
23
206
1.12
0.16
1.4
1.4
—
—
—
0
0
10
83
1.21
0.15
1.0
1.1
—
—
—
0
0
28
258
1.09
0.12
4.1
3.0
1.8
1.6
mmol/l
0.27
28
252
5
46
1.09
0.09
1.2
1.2
—
—
—
0
0
6
74
0.81
0.07
1.7
1.4
—
—
—
0
0
8
76
1.05
0.07
1.1
1.1
2.4
1.6
nmol/l
—
8
66
22
208
1.06
0.05
1.2
1.1
—
—
—
0
0
20
209
0.96
0.03
1.3
1.5
276.8
289.3
mu/l
0.11
20
183
876
8775
1.00
0.02
36.3
14.4
70.6
75.5
ml/min/173m2
5.80
757
7270
12
113
1.06
0.02
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
465.6
—
0
5
0
8
0.00
0.00
0.0
1.0
—
64.0
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2.6
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
12.8
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
5
49
1.02
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
0.00
1.0
1.0
—
—
—
0
0
6
64
0.94
0.00
1.2
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint D3_ACUTEPOSTBLEEDANAEMIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_ACUTEPOSTBLEEDANAEMIA | 2.744 [2.4, 3.14] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 3269 out of 5439 females with D3_ACUTEPOSTBLEEDANAEMIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_ACUTEPOSTBLEEDANAEMIA | 3.312 [2.83, 3.88] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.044 |
During the follow-up period (1.1.1998 — 31.12.2019), 3031 out of 4720 males with D3_ACUTEPOSTBLEEDANAEMIA died.
Mortality risk
Mortality risk for people of age
years, who have D3_ACUTEPOSTBLEEDANAEMIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.139% | 0.678% |
| 5 | 1.314% | 4.017% |
| 10 | 3.311% | 10.539% |
| 15 | 6.126% | 19.392% |
| 20 | 10.911% | 30.574% |
Relationships between endpoints
↥Index endpoint: D3_ACUTEPOSTBLEEDANAEMIA – Acute posthaemorrhagic anaemia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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