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Congenital malformations of spine and bony thorax

Endpoint Browser

Q17_CONGEN_MALFO_SPINE_BONY_THORAX_WIDE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — Q76
  • Hospital discharge: ICD-10 — Q76
  • Cause of death: ICD-10 — Q76

3 out of 7 registries used, show all original rules.

255

4. Check minimum number of events

None

255

5. Include endpoints

None

255

6. Filter based on genotype QC (FinnGen only)

244

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13
Parent code in ICD-10
Q6[5-9]|Q7
Name in latin
Malformationes congenitae columnae vertebralis et ossium thoracis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 244 152 92
Unadjusted period prevalence (%) 0.05 0.05 0.04
Median age at first event (years) 34.12 35.87 31.22

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
255
Matched controls
2550
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
47.5
87.9
53
14
Q76.30
ICD-10 Finland
Hemivertebra fusion or failure of segmentation with scoliosis
+∞
64.3
59
*
Q76.48
ICD-10 Finland
Congenital anomalies of other vertebrae, not associated with scoliosis
+∞
49.6
46
*
Q76.38
ICD-10 Finland
Congenital scoliosis due to other specified congenital bony malformation
+∞
35.2
33
*
Q76.1
ICD-10 Finland
Klippel-Feil syndrome
+∞
33.0
31
*
Q76.9
ICD-10 Finland
Congenital malformation of bony thorax, unspecified
+∞
26.5
25
*
Q76.3
ICD-10 Finland
Congenital scoliosis due to congenital bony malformation
+∞
20.1
19
*
N03AX12
ATC
[U] gabapentin; oral
4.1
19.2
65
198
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
+∞
19.0
18
*
Z31.5
ICD-10 Finland
Genetic counselling
5.1
18.3
43
98
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
19.6
16.8
25
14
ZXE20
NOMESCO Finland
More than three and less than five hours
4.0
16.4
54
160
N02AX02
ATC
tramadol; systemic, rectal
3.0
16.3
118
570
N06AX21
ATC
duloxetine; oral
4.0
16.0
52
153
Q76.2
ICD-10 Finland
Congenital spondylolisthesis
+∞
15.8
15
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.6
15.5
41
103
Q76.5
ICD-10 Finland
Cervical rib
+∞
14.7
14
*
Q76.0
ICD-10 Finland
Spina bifida occulta
+∞
14.7
14
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.4
14.6
40
103
TPH07
NOMESCO Finland
Cathetrisation of artery
4.3
14.5
41
108
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
14.3
95
432
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
14.2
54
176
Q76.68
ICD-10 Finland
Other congenital malformations of ribs
+∞
13.7
13
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.4
13.4
28
57
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
10.2
13.3
26
28
Z3226
NOMESCO Finland
Physiotherapist
3.0
13.1
75
313
M41.9
ICD-10 Finland
Scoliosis, unspecified
16.6
12.8
20
13
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
73.6
12.7
14
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.4
12.5
34
87
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.4
12.3
51
175
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.1
12.2
27
58
R4120
NOMESCO Finland
Occupational therapy
4.5
12.0
31
76
M41.5
ICD-10 Finland
Other secondary scoliosis
+∞
11.5
11
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
11.5
113
613
R4110
NOMESCO Finland
Physiotherapy
2.6
11.5
90
438
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
18.1
11.4
17
10
R03AC13
ATC
formoterol; inhalant
6.1
11.2
20
35
N03AX16
ATC
[U] pregabalin
2.9
11.2
64
265
UKC02
NOMESCO Finland
Cystoscopy
3.7
11.1
39
120
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.7
11.0
38
115
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
12.0
10.7
19
17
Q87.26
ICD-10 Finland
VATER association
+∞
10.5
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
10.1
103
561
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.6
10.1
25
59
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
9.8
28
74
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
9.8
109
616
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.7
9.7
64
284
M54.2
ICD-10 Finland
Cervicalgia
3.5
9.4
34
106
M54.5
ICD-10 Finland
Low back pain
2.3
9.3
104
586
M35.7
ICD-10 Finland
Hypermobility syndrome
13.2
9.0
15
12
WX882
NOMESCO Finland
High dependency care
4.4
8.9
23
56
NA1AD
NOMESCO Finland
Cervical spine CT examination
7.1
8.9
21
32
N03AE01
ATC
clonazepam; systemic
4.5
8.8
22
52
N06AA09
ATC
amitriptyline; systemic
3.8
8.6
28
81
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.5
8.5
31
97
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
8.4
69
337
ZX120
NOMESCO Finland
Intravenous
3.3
8.4
34
114
N02BF01
ATC
gabapentin; oral
3.5
8.4
31
98
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
8.4
37
131
L82
ICPC
Congenital anomaly musculoskeletal
+∞
8.4
8
*
Q76.78
ICD-10 Finland
Other specified congenital malformation of sternum
+∞
8.4
8
*
Q76.42
ICD-10 Finland
Congenital anomalies of sacral vetebrae
+∞
8.4
8
*
M01AH01
ATC
celecoxib; oral
3.0
8.3
41
155
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
8.1
68
335
WX402
NOMESCO Finland
General anaesthesia
2.4
7.9
67
331
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.7
7.8
25
72
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
7.7
59
279
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
19.1
7.7
11
6
Z2221
NOMESCO Finland
Medical doctor
2.2
7.7
90
510
M41.8
ICD-10 Finland
Other forms of scoliosis
25.9
7.6
10
*
J45.9
ICD-10 Finland
Asthma, unspecified
2.5
7.6
57
267
L28
ICPC
Limited function/disability (L)
2.8
7.6
41
163
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
7.5
50
221
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
7.5
30
100
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.1
7.4
21
55
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
11.3
7.4
13
12
Q76.40
ICD-10 Finland
Congenital absence of vertebrae without scoliosis
+∞
7.3
7
*
M54.6
ICD-10 Finland
Pain in thoracic spine
3.3
7.3
29
96
Q25.0
ICD-10 Finland
Patent ductus arteriosus
16.3
7.3
11
7
ZXA05
NOMESCO Finland
Left side
2.4
7.2
57
272
R20.2
ICD-10 Finland
Paraesthesia of skin
3.4
7.2
27
86
A28
ICPC
Limited function/disability NOS
2.9
7.0
35
133
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
7.0
61
305
XKC03
NOMESCO Finland
Water cystometry
7.0
6.9
16
24
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
7.5
6.8
15
21
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
17.3
6.8
10
6
M41.2
ICD-10 Finland
Other idiopathic scoliosis
17.3
6.8
10
6
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
17.3
6.8
10
6
SPAT1229
SPAT
Assessment of need for aid
4.2
6.7
18
45
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.2
6.7
27
90
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
4.4
6.7
17
41
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
12.7
6.6
11
9
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.7
6.5
14
19
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.4
6.5
24
76
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.5
6.4
13
16
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
8.5
6.4
13
16
Z2446
NOMESCO Finland
Social worker
2.7
6.4
37
152
J45.1
ICD-10 Finland
Nonallergic asthma
2.9
6.3
32
122
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.1
6.3
28
99
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
6.3
44
198
M79.0
ICD-10 Finland
Rheumatism, unspecified
5.6
6.3
17
32
Q66.0
ICD-10 Finland
Talipes equinovarus
+∞
6.3
6
*
Q76.8
ICD-10 Finland
Other congenital malformations of bony thorax
+∞
6.3
6
*
NAK30
NOMESCO Finland
Osteotomy of spine
+∞
6.3
6
*
WX892
NOMESCO Finland
Monitored bed care
3.2
6.3
25
83
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
27.4
6.3
8
*
J45.8
ICD-10 Finland
Mixed asthma
6.0
6.3
16
28
B02AA02
ATC
tranexamic acid; systemic
2.5
6.2
41
180
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
6.2
67
364
G44.2
ICD-10 Finland
Tension-type headache
2.5
6.2
44
200
Z3231
NOMESCO Finland
Registered nurse
2.0
6.2
88
530
N94.4
ICD-10 Finland
Primary dysmenorrhoea
5.4
6.1
17
33
R5110, ,
SPAT
5.8
6.1
16
29

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
48
236
2.27
5.63
3.2
2.3
—
—
—
0
0
34
145
2.55
5.44
10.6
12.5
96.93
95.72
%
0.77
34
138
93
592
1.90
5.42
3.0
2.4
—
—
—
0
0
36
162
2.42
5.14
10.3
11.5
5.53
5.32
kpa
0.59
36
154
36
162
2.42
5.14
10.3
11.5
14.96
13.63
kpa
0.45
36
154
180
1424
1.90
5.11
8.3
6.7
83.02
86.77
u/l
0.43
170
1330
42
212
2.17
4.60
2.7
2.6
20.49
23.70
%
0.68
36
184
145
1097
1.75
4.53
9.4
7.1
0.04
0.04
e9/l
0.10
139
958
145
1099
1.74
4.48
9.3
7.1
0.56
0.55
e9/l
0.08
139
960
69
421
1.88
4.47
3.8
2.7
1.53
0.87
mg/l
0.59
52
323
30
133
2.42
4.42
11.1
11.5
120.57
123.40
g/l
0.34
30
128
21
78
2.84
4.37
13.3
16.7
—
—
—
0
0
148
1136
1.72
4.30
9.7
7.5
0.17
0.20
e9/l
1.53
138
1013
39
199
2.13
4.15
14.8
7.7
104.95
104.38
mmol/l
0.42
39
199
41
214
2.09
4.12
15.5
9.9
—
—
—
0
0
96
667
1.70
3.94
7.9
9.9
0.99
1.17
inr
6.12
22
205
29
134
2.31
3.91
1.7
4.0
69.56
68.27
e9/l
0.07
21
99
137
1049
1.66
3.86
8.7
7.5
—
—
—
0
0
62
383
1.82
3.81
4.3
3.0
536.44
560.52
mosm/kgh2o
0.32
55
327
119
883
1.65
3.76
13.8
8.6
1.21
1.22
mmol/l
0.28
114
763
69
443
1.76
3.72
4.7
3.4
—
—
—
0
0
145
1141
1.63
3.56
9.4
7.1
1.89
2.02
e9/l
1.12
139
1030
47
280
1.83
3.22
1.6
1.6
136170669.17
454.32
pmol/l
0.49
47
242
62
402
1.72
3.19
5.5
4.0
—
—
—
0
0
82
579
1.61
3.04
2.9
2.8
2.35
2.36
mmol/l
0.20
74
525
20
89
2.35
2.95
13.2
8.9
—
—
—
0
0
152
1242
1.55
2.94
10.6
10.0
3.98
3.93
e9/l
0.08
145
1083
24
116
2.18
2.94
1.4
2.0
8.87
9.07
u/l
0.03
19
89
68
463
1.64
2.90
3.3
2.7
3.21
2.84
mg/l
0.64
60
400
118
916
1.54
2.86
4.9
6.6
10.86
11.10
umol/l
0.07
112
864
239
2208
2.31
2.80
15.9
9.9
—
—
—
0
0
15
60
2.59
2.75
3.1
2.6
—
—
—
0
0
31
171
1.93
2.69
15.9
8.1
24.40
23.77
mmol/l
0.78
31
171
60
403
1.64
2.68
4.5
2.8
7.28
5.04
e6/l
0.58
54
357
122
968
1.50
2.60
5.3
4.8
0.00
0.00
estimate
-0.00
20
193
216
1944
1.73
2.55
20.3
14.4
14.52
14.10
%
0.54
216
1916
144
1187
1.49
2.51
3.3
3.1
—
—
—
0
0
163
1378
1.51
2.51
5.7
4.0
—
—
—
0
0
126
1013
1.48
2.48
10.1
9.4
0.00
0.00
e9/l
0.50
113
806
39
238
1.75
2.47
14.4
7.9
1.96
1.73
mmol/l
0.24
34
189
77
560
1.54
2.45
8.3
7.9
—
—
—
0
0
122
979
1.47
2.40
3.9
3.5
0.00
0.00
estimate
-0.00
20
186
19
91
2.18
2.40
14.5
11.6
25.95
25.43
mmol/l
0.20
19
85
12
46
2.69
2.39
1.3
3.7
—
—
—
0
0
81
599
1.52
2.38
2.1
1.8
92.69
93.67
pmol/l
0.06
47
301
38
234
1.73
2.34
1.5
1.6
1138.13
1143.91
nmol/l
0.01
32
178
74
539
1.53
2.32
6.4
3.3
—
—
—
0
0
44
283
1.67
2.32
3.8
3.3
1367.97
313.01
ng/l
0.92
29
170
75
549
1.52
2.30
4.0
2.5
—
—
—
0
0
91
695
1.48
2.27
6.9
4.2
83.45
35.73
e6/l
0.54
66
484
73
535
1.51
2.22
6.4
3.4
0.52
0.21
e6/l
0.39
59
407
14
61
2.37
2.19
16.4
12.7
1.98
1.57
%
0.68
14
55
208
1876
1.59
2.17
5.8
4.6
1.78
2.46
mu/l
0.54
202
1745
120
973
1.44
2.17
3.9
3.4
0.00
0.00
estimate
-0.00
21
202
9
30
3.07
2.17
1.3
1.2
—
—
—
0
0
10
37
2.77
2.09
2.2
5.8
—
—
—
0
0
52
723
0.65
2.08
2.0
2.5
—
—
—
0
0
24
133
1.89
2.08
6.8
6.1
47.42
60.23
ng/l
0.94
24
125
170
1478
1.45
2.06
4.4
4.3
8.18
9.16
mm/h
0.81
164
1368
102
809
1.43
2.06
3.7
3.1
5.71
5.86
ph
—
7
77
8
26
3.14
2.03
1.4
4.1
47.42
36.67
%
—
8
26
53
369
1.55
2.03
2.4
2.8
133.16
104.98
ug/g
0.18
36
281
46
311
1.58
1.99
5.3
3.3
3.09
2.73
e6/l
0.13
28
181
5
11
4.61
1.95
3.2
2.1
406.60
1133.27
u/ml
—
5
11
27
159
1.78
1.94
13.4
6.7
—
—
—
0
0
12
53
2.33
1.83
1.2
1.3
—
—
—
0
0
5
12
4.23
1.83
1.0
1.0
880.40
1425.75
miu/ml
—
5
12
0
47
0.00
1.72
0.0
1.1
—
2.39
—
0
7
5
13
3.90
1.72
2.8
2.3
36480.00
33585.00
ug/l
—
5
13
35
231
1.60
1.68
3.0
1.5
—
—
—
0
0
73
563
1.42
1.67
2.6
2.7
60.85
55.16
u/l
0.39
68
524
226
2112
1.62
1.65
18.4
11.5
22.34
21.08
mg/l
0.24
190
1559
75
583
1.41
1.64
6.4
3.6
23.33
44.12
e6/l
0.87
61
453
8
32
2.55
1.61
2.5
6.0
—
—
—
0
0
12
57
2.16
1.57
1.3
3.1
1.08
8.02
e6/l
0.76
12
44
12
57
2.16
1.57
1.4
3.2
181.83
300.49
e6/l
0.26
12
45
130
1112
1.34
1.55
10.3
5.8
6.34
6.46
mmol/l
0.22
124
1005
8
33
2.47
1.55
25.9
18.8
106.88
105.11
mmol/l
—
8
28
8
33
2.47
1.55
25.9
18.8
10.75
10.18
mmol/l
—
8
28
0
42
0.00
1.54
0.0
1.2
—
—
—
0
0
64
492
1.40
1.48
4.7
3.6
7.39
7.40
ph
—
8
90
12
61
2.01
1.35
18.3
12.7
0.86
0.92
%
0.20
12
56
71
565
1.36
1.33
3.8
3.2
36.13
33.82
ng/l
0.05
41
307
21
130
1.67
1.31
5.3
3.5
—
—
—
0
0
12
62
1.98
1.30
7.8
4.4
—
—
—
0
0
15
85
1.81
1.26
4.3
1.8
—
—
—
0
0
65
516
1.35
1.23
4.4
3.5
7.51
8.47
mmol/l
0.83
58
462
46
345
1.41
1.23
1.2
1.3
4.86
8.44
u/ml
0.35
23
127
64
509
1.34
1.20
4.4
3.6
0.00
0.01
estimate
0.50
18
193
8
38
2.14
1.19
46.4
10.3
—
—
—
0
0
40
296
1.42
1.15
1.5
1.5
364.44
493.97
titre
—
9
63
14
81
1.77
1.11
2.1
1.6
—
—
—
0
0
24
162
1.53
1.09
2.2
2.3
—
14.59
—
0
9
9
160
0.55
1.02
1.3
1.4
—
—
—
0
0
9
48
1.91
1.01
23.6
14.8
1.09
1.19
mmol/l
—
9
40
30
219
1.42
0.95
1.6
1.5
—
—
—
0
0
197
1847
1.29
0.94
3.9
4.1
2.71
2.83
mmol/l
1.31
191
1735
6
27
2.25
0.94
3.5
2.3
—
—
—
0
0
26
185
1.45
0.94
1.2
1.3
44.22
150.89
iu/ml
—
8
72
57
465
1.29
0.90
4.3
3.2
1.02
1.02
kg/l
—
8
66
6
29
2.09
0.90
1.2
1.7
277.33
287.06
mosm/kgh2o
—
6
18
30
222
1.40
0.89
1.4
1.3
—
—
—
0
0
8
43
1.89
0.88
1.3
1.3
—
—
—
0
0
16
104
1.57
0.87
1.9
2.7
66.94
66.25
g/l
0.13
16
98
8
45
1.80
0.85
2.6
1.9
—
—
—
0
0
10
57
1.79
0.85
2.2
1.5
—
—
—
0
0
11
65
1.72
0.83
6.6
8.2
—
—
—
0
0
45
360
1.30
0.82
1.3
1.3
37.70
27.77
iu/ml
0.22
11
108
0
24
0.00
0.79
0.0
3.5
—
48.48
—
0
24
8
48
1.69
0.79
2.3
1.6
0.22
0.31
nmol/l
—
8
39
48
390
1.28
0.78
3.7
3.9
5.27
52.23
mg/mmol
0.59
33
270
245
2389
1.65
0.78
25.6
16.9
260.04
258.71
e9/l
0.12
245
2329
5
24
2.10
0.75
1.2
1.5
—
—
nmol/l
—
0
0
245
2391
1.63
0.75
26.4
17.0
40.40
40.32
%
0.09
229
2290
193
1825
1.24
0.73
3.6
3.8
1.45
1.47
mmol/l
0.23
186
1712
245
2392
1.62
0.73
25.5
16.8
89.38
89.36
fl
0.02
245
2358
7
39
1.82
0.73
6.1
4.0
61.29
55.64
%
—
7
39
7
39
1.82
0.73
6.1
3.9
3.50
4.11
e9/l
—
7
39
71
610
1.23
0.73
1.7
1.5
1.68
1.99
g/l
1.62
50
343
245
2393
1.61
0.71
25.5
16.7
29.84
29.91
pg
0.23
245
2358
19
135
1.44
0.71
3.9
4.1
—
—
—
0
0
5
27
1.87
0.69
1.2
1.4
—
—
—
0
0
245
2395
1.59
0.68
25.8
17.0
134.91
135.84
g/l
0.51
245
2362
16
111
1.47
0.67
2.5
2.0
—
—
—
0
0
13
86
1.54
0.67
30.5
6.0
0.78
0.69
%
0.38
13
86
20
146
1.40
0.66
1.3
1.3
—
34.97
—
0
7
45
372
1.25
0.65
3.6
3.4
1498.11
227.60
mg/l
0.40
33
264
50
419
1.24
0.64
4.1
3.3
—
—
—
0
0
5
29
1.74
0.64
1.2
1.4
0.46
0.45
nmol/l
—
5
24
26
201
1.33
0.62
1.6
1.4
—
—
—
0
0
186
1766
1.20
0.60
3.4
3.5
1.22
1.25
mmol/l
0.27
181
1654
10
143
0.69
0.49
1.5
1.7
—
—
—
0
0
7
49
1.44
0.46
1.1
1.1
—
—
—
0
0
7
49
1.44
0.46
1.1
1.1
—
—
—
0
0
31
260
1.22
0.42
1.2
1.2
—
—
—
0
0
186
1788
1.15
0.42
3.9
3.5
5.63
5.71
mmol/l
0.26
178
1653
5
33
1.53
0.41
1.2
1.4
—
—
—
0
0
11
79
1.41
0.41
1.1
1.2
—
—
—
0
0
11
79
1.41
0.41
1.9
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
2.82
—
0
16
30
252
1.22
0.40
2.1
4.9
4.29
8.50
umol/l
1.55
24
219
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
20
161
1.26
0.38
2.4
2.6
7259.46
3425.01
u/l
0.23
13
66
14
107
1.33
0.38
30.6
7.0
131.21
131.17
g/l
0.00
14
107
17
134
1.29
0.38
1.2
1.2
—
—
—
0
0
16
125
1.30
0.38
2.1
1.9
—
—
—
0
0
5
37
1.36
0.37
1.0
1.0
—
—
—
0
0
14
179
0.77
0.37
3.2
3.6
—
—
—
0
0
11
81
1.37
0.37
1.5
1.4
—
1.67
—
0
6
24
199
1.23
0.36
1.4
1.2
—
—
—
0
0
5
76
0.65
0.36
1.8
2.0
257.60
169.85
u/ml
—
5
41
37
321
1.18
0.36
1.3
1.6
—
—
—
0
0
6
42
1.44
0.36
1.5
1.2
—
—
—
0
0
16
127
1.28
0.34
1.2
1.4
—
—
—
0
0
73
676
1.11
0.29
1.4
1.5
0.56
1.63
u/ml
1.83
17
153
9
75
1.21
0.25
1.3
2.0
—
—
—
0
0
10
79
1.28
0.22
3.1
2.6
—
—
—
0
0
5
41
1.22
0.22
2.4
3.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.9
—
648.00
—
0
5
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
20
174
1.16
0.20
2.9
2.4
0.50
0.77
ug/l
1.85
13
97
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.5
1.3
—
—
—
0
0
37
402
0.91
0.18
1.5
1.7
—
—
—
0
0
7
62
1.13
0.17
1.1
1.3
—
2.88
—
0
10
10
82
1.23
0.17
2.6
2.2
—
—
—
0
0
37
398
0.92
0.15
1.6
1.8
—
—
—
0
0
19
212
0.89
0.14
1.6
1.4
—
—
—
0
0
24
263
0.90
0.14
1.1
1.3
—
—
—
0
0
74
711
1.06
0.12
2.2
1.9
—
—
—
0
0
18
164
1.10
0.10
3.9
1.5
—
—
—
0
0
53
509
1.05
0.09
1.5
1.7
—
—
—
0
0
16
175
0.91
0.09
4.2
1.5
—
—
—
0
0
19
175
1.09
0.08
3.8
1.6
—
—
—
0
0
19
175
1.09
0.08
3.7
1.5
—
—
—
0
0
5
60
0.83
0.08
2.2
1.3
—
—
—
0
0
5
62
0.80
0.08
1.4
1.1
—
—
—
0
0
65
630
1.04
0.08
1.7
2.0
—
—
—
0
0
8
78
1.03
0.07
1.5
1.2
—
—
—
0
0
19
177
1.08
0.07
3.7
1.5
—
—
—
0
0
8
95
0.84
0.07
1.0
1.1
—
—
—
0
0
18
193
0.93
0.06
1.6
1.5
—
—
—
0
0
9
103
0.87
0.06
1.4
1.6
—
—
—
0
0
13
119
1.10
0.06
1.0
1.2
—
—
—
0
0
15
139
1.08
0.05
4.5
1.6
—
—
—
0
0
66
676
0.97
0.05
1.5
1.7
—
—
—
0
0
10
92
1.09
0.03
4.8
6.3
0.19
0.32
g/l
—
5
54
13
122
1.07
0.02
2.5
1.7
—
—
—
0
0
14
133
1.06
0.01
1.7
1.5
—
—
—
0
0
23
236
0.97
0.00
2.2
1.9
—
—
—
0
0
13
128
1.02
0.00
3.2
3.9
3.63
43.22
ug/l
—
7
96
57
566
1.01
0.00
2.5
3.0
—
—
—
0
0
11
107
1.03
0.00
1.4
1.2
—
—
—
0
0
13
133
0.98
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
156.07
—
0
9
9
99
0.91
-0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.5
—
66.00
—
0
5
7
74
0.94
-0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
99
0.91
-0.00
1.4
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
153.88
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
0.76
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.9
—
51.11
—
0
9
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
7.63
—
0
9
5
55
0.91
-0.00
1.2
1.6
0.89
0.56
nmol/l
—
5
48
0
9
0.00
-0.00
0.0
1.7
—
1688.33
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
4.95
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_CONGEN_MALFO_SPINE_BONY_THORAX_WIDE – Congenital malformations of spine and bony thorax

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).