Haematosalpinx/Haematoma of broad ligament

N14_MAEMABROAD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N83.6, N83.7
  • Hospital discharge: ICD-9 6207
  • Cause of death: ICD-10 N83.6, N83.7
  • Cause of death: ICD-9 6207

2 out of 7 registries used, show all original rules.

71

4. Check minimum number of events

None

71

5. Include endpoints

None

71

6. Filter based on genotype QC (FinnGen only)

65

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 390 390 -
Only index persons 377 377 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population - 39.54 -
Only index persons - 39.34 -

-FinnGen-

Key figures

All Female Male
Number of individuals 65 65 -
Unadjusted period prevalence (%) 0.02 0.02 -
Median age at first event (years) 39.35 39.35 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
71
Matched controls
710
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N83.6
ICD-10 Finland
Haematosalpinx
+∞
57.2
47
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
70.7
29.0
32
8
N83.7
ICD-10 Finland
Haematoma of broad ligament
+∞
20.8
19
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
7.8
17.2
43
117
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
7.1
15.6
37
94
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
+∞
15.1
14
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
18.0
12.9
20
15
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
10.7
10
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
4.9
10.2
41
154
JAH01
NOMESCO Finland
Laparoscopy
26.0
9.8
13
6
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
9.2
9.0
19
27
N81.6
ICD-10 Finland
Rectocele
101.6
8.6
9
*
N80.1
ICD-10 Finland
Endometriosis of ovary
101.6
8.6
9
*
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
+∞
8.5
8
*
N84.0
ICD-10 Finland
Polyp of corpus uteri
+∞
8.5
8
*
N83.1
ICD-10 Finland
Corpus luteum cyst
+∞
7.4
7
*
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
+∞
7.4
7
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
3.9
7.2
46
227
TLC00
NOMESCO Finland
Insertion of intrauterine device
12.8
7.1
12
11
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
20.3
6.4
9
5
N97.8
ICD-10 Finland
Female infertility of other origin
+∞
6.3
6
*
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
+∞
6.3
6
*
N97.1
ICD-10 Finland
Female infertility of tubal origin
+∞
6.3
6
*
N02AX02
ATC
tramadol; systemic, rectal
3.5
6.2
37
170
LCA06
NOMESCO Finland
Biopsy of endometrium
8.1
6.1
13
19

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
11
13
9.77
5.80
2.7
1.5
53.18
98.00
pmol/l
0.45
11
13
56
348
3.88
5.53
4.6
3.5
—
—
—
0
0
28
140
2.65
3.67
2.5
2.3
—
—
—
0
0
22
103
2.65
3.24
1.9
1.8
0.45
0.75
mg/l
1.23
16
83
23
111
2.59
3.18
5.8
3.1
1.02
1.02
kg/l
—
6
17
26
136
2.44
3.03
2.3
2.3
51.92
57.88
u/l
0.64
26
127
13
48
3.09
2.90
1.5
1.5
—
—
—
0
0
5
6
8.84
2.79
1.0
1.0
—
—
—
0
0
34
215
2.12
2.43
2.3
1.7
—
—
—
0
0
37
250
2.00
2.14
3.4
6.0
8.81
9.04
umol/l
0.06
37
239
7
20
3.76
2.11
6.1
4.9
—
—
—
0
0
15
71
2.41
2.10
1.5
1.9
—
—
—
0
0
5
11
4.80
1.97
1.0
2.4
—
—
—
0
0
12
53
2.52
1.93
1.3
1.2
—
—
—
0
0
11
47
2.59
1.88
6.0
5.6
102.91
105.19
mmol/l
0.39
11
47
7
24
3.12
1.77
1.4
1.5
—
—
—
0
0
24
148
1.94
1.74
1.3
2.0
—
—
—
0
0
11
49
2.47
1.74
1.2
1.2
—
—
—
0
0
7
26
2.87
1.62
5.9
6.0
0.74
0.59
%
—
7
26
7
26
2.87
1.62
5.9
6.0
1.37
1.33
%
—
7
26
6
20
3.18
1.62
1.3
1.0
—
—
—
0
0
7
27
2.76
1.56
5.9
5.8
95.76
95.01
%
—
7
27
5
15
3.50
1.55
1.0
1.9
—
4.90
—
0
7
23
147
1.84
1.47
1.7
2.7
10.93
18.17
ng/l
—
10
78
11
53
2.27
1.47
1.6
1.3
87.33
127.60
iu/ml
—
6
28
7
29
2.56
1.43
2.3
1.8
—
—
—
0
0
10
47
2.31
1.41
1.4
2.3
2.80
4.03
umol/l
—
10
37
5
17
3.08
1.38
1.0
1.0
—
—
—
0
0
16
94
1.91
1.31
2.7
3.6
—
—
—
0
0
5
19
2.75
1.23
4.8
5.9
25.10
23.95
mmol/l
—
5
19
18
113
1.79
1.20
3.8
3.1
—
—
—
0
0
27
191
1.67
1.20
9.5
7.9
1.13
1.09
inr
—
7
49
14
81
1.91
1.19
3.7
2.6
68.78
89.38
ng/l
—
9
47
8
40
2.12
1.16
4.3
3.3
—
—
—
0
0
8
42
2.02
0.92
1.3
1.8
—
—
—
0
0
17
240
0.62
0.92
1.4
2.4
—
—
—
0
0
8
43
1.97
0.91
2.4
3.6
4.54
4.60
pmol/l
—
8
37
48
411
1.52
0.84
4.9
3.4
9.87
10.21
mm/h
0.10
48
383
24
182
1.48
0.75
1.8
1.7
99.20
92.92
pmol/l
—
10
94
8
51
1.64
0.63
1.1
1.1
—
—
—
0
0
0
21
0.00
0.61
0.0
2.0
—
1.55
—
0
21
17
125
1.47
0.61
1.7
2.0
122.47
178.01
u/l
0.39
17
117
8
53
1.57
0.61
1.9
1.3
—
—
—
0
0
5
85
0.56
0.61
1.8
1.5
430.00
98649074.03
pmol/l
—
5
74
0
23
0.00
0.59
0.0
2.9
—
22.74
—
0
23
6
39
1.59
0.54
1.2
1.4
—
—
—
0
0
16
119
1.44
0.54
2.2
2.8
—
—
—
0
0
17
128
1.43
0.54
1.6
1.7
—
—
—
0
0
62
582
1.51
0.49
15.2
9.1
29.86
19.75
mg/l
1.14
52
420
29
245
1.31
0.46
3.5
5.4
—
—
—
0
0
17
133
1.37
0.44
4.8
2.3
—
—
—
0
0
5
33
1.55
0.42
2.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
2.0
—
0.63
—
0
18
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
2.0
—
24.04
—
0
19
5
36
1.42
0.39
3.0
4.6
—
—
—
0
0
19
155
1.31
0.37
1.7
1.8
—
—
—
0
0
6
44
1.40
0.35
1.0
1.2
—
—
—
0
0
6
45
1.36
0.35
2.0
2.4
20.00
21.49
%
—
6
37
17
140
1.28
0.31
3.1
2.8
8.79
64.40
e6/l
1.60
12
90
8
62
1.33
0.29
1.8
1.5
—
—
—
0
0
65
627
1.43
0.25
12.1
8.9
—
—
—
0
0
59
565
1.26
0.24
14.2
9.8
139.58
139.82
mmol/l
0.27
59
548
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
1.45
—
0
10
59
567
1.24
0.21
14.1
9.8
3.92
3.92
mmol/l
0.02
59
548
38
353
1.16
0.20
3.6
2.7
—
—
—
0
0
7
58
1.23
0.19
1.6
2.3
11.14
14.42
umol/l
—
7
52
15
170
0.85
0.16
1.5
1.6
—
—
—
0
0
7
86
0.79
0.15
1.1
1.3
—
—
—
0
0
14
122
1.18
0.15
3.7
3.7
1.44
14.60
mg/mmol
—
8
71
12
104
1.19
0.13
3.4
2.5
—
—
—
0
0
13
114
1.17
0.13
3.2
3.1
11.24
713.54
mg/l
—
7
68
6
58
1.04
0.08
1.2
1.4
—
—
—
0
0
7
63
1.12
0.08
1.0
1.4
—
—
—
0
0
7
81
0.85
0.07
1.6
1.4
—
—
—
0
0
59
581
1.09
0.04
4.0
3.4
1.50
1.59
mmol/l
0.94
54
549
14
138
1.02
0.00
5.1
6.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
6.0
—
1093.88
—
0
8
0
7
0.00
-0.00
0.0
3.4
—
1.31
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
174.67
—
0
6
8
87
0.91
-0.00
2.3
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.2
—
2208.75
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
9.37
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
97
0.92
-0.00
1.4
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
19.57
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
1.06
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
105.33
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
4.08
—
0
6
0
8
0.00
-0.00
0.0
1.8
—
53.13
—
0
8

Mortality – FinRegistry

Association

Association between endpoint N14_MAEMABROAD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_MAEMABROAD.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: N14_MAEMABROAD – Haematosalpinx/Haematoma of broad ligament

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data