Haematosalpinx/Haematoma of broad ligament

N14_MAEMABROAD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N83.6, N83.7
  • Hospital discharge: ICD-9 6207
  • Cause of death: ICD-10 N83.6, N83.7
  • Cause of death: ICD-9 6207

2 out of 7 registries used, show all original rules.

71

4. Check minimum number of events

None

71

5. Include endpoints

None

71

6. Filter based on genotype QC (FinnGen only)

71

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 390 390 -
Only index persons 377 377 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population - 39.54 -
Only index persons - 39.34 -

-FinnGen-

Key figures

All Female Male
Number of individuals 71 71 -
Unadjusted period prevalence (%) 0.02 0.02 -
Median age at first event (years) 37.87 37.87 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
66
Matched controls
659
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N83.6
ICD-10 Finland
Haematosalpinx
+∞
52.1
43
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
94.9
26.6
28
5
N83.7
ICD-10 Finland
Haematoma of broad ligament
+∞
19.8
18
*
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
+∞
14.0
13
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
21.6
13.1
19
12
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
7.0
11.8
37
102
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
6.7
11.1
35
95
JAH01
NOMESCO Finland
Laparoscopy
17.6
8.6
13
9
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
10.0
8.5
17
22
N80.1
ICD-10 Finland
Endometriosis of ovary
+∞
8.5
8
*
N81.6
ICD-10 Finland
Rectocele
51.3
7.9
9
*
N83.1
ICD-10 Finland
Corpus luteum cyst
+∞
7.4
7
*
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
23.1
7.4
10
5
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
4.1
6.9
36
148
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
+∞
6.3
6
*

Mortality – FinRegistry

Association

Association between endpoint N14_MAEMABROAD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_MAEMABROAD.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: N14_MAEMABROAD – Haematosalpinx/Haematoma of broad ligament

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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