Slow fetal growth and fetal malnutrition

P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P05
  • Cause of death: ICD-10 P05

2 out of 7 registries used, show all original rules.

221

4. Check minimum number of events

None

221

5. Include endpoints

None

221

6. Filter based on genotype QC (FinnGen only)

203

Control definitions (FinnGen only)

Control exclude
P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P0[5-8]
Name in latin
Crescentia tarda et malnutritio fetalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12946 6759 6182
Only index persons 6781 3568 3213
Unadjusted period prevalence (%)
Whole population 0.18 0.19 0.17
Only index persons 0.13 0.13 0.12
Median age at first event (years)
Whole population 0.01 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 203 127 76
Unadjusted period prevalence (%) 0.04 0.05 0.03
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
220
Matched controls
2181
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
54.0
163.5
103
35
P05.1
ICD-10 Finland
Small for gestational age
+∞
156.1
131
*
P07.3
ICD-10 Finland
Other preterm infants
+∞
103.2
91
*
P05.0
ICD-10 Finland
Light for gestational age
+∞
94.5
84
*
602
Kela drug reimbursment
Children's severe malnutrition
11.2
42.9
51
57
P07.12
ICD-10 Finland
Other low birth weight 2000-2499 g
+∞
40.8
38
*
P07.11
ICD-10 Finland
Other low birth weight 1500-1999 g
+∞
38.6
36
*
P70.4
ICD-10 Finland
Other neonatal hypoglycaemia
14.0
35.5
35
29
E34.31
ICD-10 Finland
Short stature, prenatal disorder
34.1
27.2
35
12
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
6.8
21.4
37
63
WX722
NOMESCO Finland
PEEP
9.6
20.9
26
30
P07.2
ICD-10 Finland
Extreme immaturity
+∞
17.9
17
*
P00.0
ICD-10 Finland
Fetus and newborn affected by maternal hypertensive disorders
21.3
17.2
25
13
P59.0
ICD-10 Finland
Neonatal jaundice associated with preterm delivery
54.2
17.2
20
*
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
+∞
16.8
16
*
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
8.0
16.7
24
33
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
12.0
14.9
27
25
P01.5
ICD-10 Finland
Fetus and newborn affected by multiple pregnancy
56.7
14.0
16
*
P27.1
ICD-10 Finland
Bronchopulmonary dysplasia originating in the perinatal period
+∞
13.6
13
*
P07.10
ICD-10 Finland
Other low birth weight 1000-1499 g
+∞
13.6
13
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.8
13.0
47
147
P05.9
ICD-10 Finland
Slow fetal growth, unspecified
+∞
12.6
12
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.2
12.6
37
100
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.0
12.1
71
299
A11JC
ATC
Vitamins, other combinations
49.1
12.0
14
*
P07.1
ICD-10 Finland
Other low birth weight
+∞
11.5
11
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
11.5
11
*
R4110
NOMESCO Finland
Physiotherapy
2.7
10.9
80
378
P29.30
ICD-10 Finland
Delayed closure of the ductus arteriosus
57.1
9.7
11
*
H01AC01
ATC
somatropin; parenteral
4.3
9.5
26
66
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.0
8.8
43
161
R62.0
ICD-10 Finland
Delayed milestone
3.5
8.7
33
106
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
8.5
61
280
Z38.3
ICD-10 Finland
Twin, born in hospital
92.7
8.4
9
*
P07.01
ICD-10 Finland
Extremely low birth weight 500-749 g
+∞
8.4
8
*
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
8.2
77
400
WX730
NOMESCO Finland
Conventional respirator
17.9
8.1
12
7
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
8.1
93
527
RK312, ,
NOMESCO Finland
19.0
7.6
11
6
WW804
NOMESCO Finland
Transfer from treating institution to higher-Level care, accompanied by doctor
12.4
7.6
13
11
Z3226
NOMESCO Finland
Physiotherapist
2.3
7.6
73
381
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
7.6
60
287
F82
ICD-10 Finland
Specific developmental disorder of motor function
4.2
7.5
21
54
Z3231
NOMESCO Finland
Registered nurse
2.1
6.8
102
633
301
Kela drug reimbursment
Growth hormone
7.5
6.8
15
21
P22.9
ICD-10 Finland
Respiratory distress of newborn, unspecified
8.2
6.7
14
18
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
6.5
79
450
Z2446
NOMESCO Finland
Social worker
2.4
6.4
54
264
P07.02
ICD-10 Finland
Extremely low birth weight 750-999 g
+∞
6.3
6
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
6.2
45
205
WX882
NOMESCO Finland
High dependency care
2.6
6.2
40
173
Q21.10
ICD-10 Finland
Persistent ostium secundum
4.3
6.1
16
39

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
8
7
11.69
4.79
1.3
1.7
—
—
—
0
0
36
168
2.34
4.70
2.8
2.5
4.58
5.51
u/l
0.50
21
99
16
50
3.34
4.36
5.3
6.5
2.12
2.54
ug/l
0.26
16
50
10
19
5.41
3.84
2.4
1.4
—
—
—
0
0
33
174
2.04
3.19
1.5
1.3
21.88
19.27
nmol/l
0.33
28
149
41
234
1.91
3.17
1.7
1.4
99.41
365.54
u/ml
1.79
34
223
29
150
2.06
2.95
3.1
2.5
8.87
6.39
iu/l
0.35
20
95
166
1420
1.65
2.59
4.2
3.7
2.33
2.02
mu/l
2.08
157
1325
28
151
1.96
2.55
23.6
14.8
106.07
105.65
mmol/l
0.31
28
151
14
58
2.49
2.38
1.2
1.3
—
—
—
0
0
9
28
3.28
2.31
2.0
2.8
17.99
17.13
%
—
9
16
6
15
4.05
2.03
7.5
5.9
1.59
1.55
mmol/l
—
6
15
189
1707
1.69
1.99
8.2
7.9
—
—
—
0
0
192
1742
1.73
1.97
10.4
11.6
22.42
23.81
mg/l
0.22
125
1159
17
84
2.09
1.97
1.5
1.6
—
—
—
0
0
110
895
1.44
1.90
4.9
5.0
137.23
133.06
u/l
0.18
103
842
9
36
2.54
1.74
4.7
6.2
—
—
—
0
0
10
40
2.55
1.68
3.7
10.0
—
—
—
0
0
14
69
2.08
1.65
16.3
19.8
0.72
0.73
%
0.05
14
69
14
70
2.05
1.59
16.3
19.5
96.04
95.43
%
0.16
14
70
14
70
2.05
1.59
16.3
19.5
0.99
1.02
%
0.11
14
70
18
99
1.87
1.59
1.7
1.7
—
—
—
0
0
148
1295
1.41
1.56
3.8
3.3
14.41
14.38
pmol/l
0.04
137
1157
14
71
2.02
1.54
16.3
18.9
22.79
24.21
mmol/l
0.92
14
71
47
339
1.48
1.49
5.0
2.8
1.02
1.02
kg/l
0.44
11
62
99
824
1.35
1.37
16.1
14.9
1.23
1.23
mmol/l
0.03
93
786
43
311
1.46
1.35
1.5
1.4
97.16
98.99
pmol/l
0.09
16
157
101
847
1.34
1.31
14.3
13.4
1.23
1.23
mmol/l
0.09
92
785
130
1133
1.34
1.29
7.9
12.4
0.20
0.21
e9/l
0.22
110
937
25
163
1.59
1.26
2.3
2.4
—
—
—
0
0
63
496
1.36
1.23
7.8
9.8
38.68
37.57
g/l
0.96
63
474
12
63
1.94
1.22
1.4
1.8
—
—
—
0
0
0
33
0.00
1.17
0.0
1.1
—
—
—
0
0
44
330
1.40
1.14
5.8
3.4
0.00
0.00
estimate
—
8
118
90
758
1.30
1.09
3.4
2.9
35.23
36.28
mmol/mol
0.47
83
711
54
423
1.35
1.08
2.4
4.1
—
—
—
0
0
5
21
2.39
1.08
1.2
1.0
—
—
—
0
0
73
858
0.77
1.06
2.0
1.9
11.95
3.50
u/ml
0.78
15
143
133
1182
1.29
1.06
8.9
13.0
3.53
3.42
e9/l
0.22
110
958
9
46
1.98
1.04
2.8
4.0
26.89
24.28
umol/l
—
9
46
19
122
1.60
1.03
1.1
1.3
—
—
—
0
0
80
668
1.29
1.03
6.2
11.7
—
—
—
0
0
7
35
2.01
1.00
1.0
1.0
—
—
—
0
0
73
605
1.29
0.99
4.5
3.2
6.59
6.22
ph
0.57
11
81
12
195
0.59
0.99
1.8
1.8
—
—
—
0
0
16
241
0.63
0.97
1.4
1.8
—
—
—
0
0
42
322
1.36
0.97
4.3
3.4
7.41
7.39
ph
—
7
57
9
150
0.58
0.92
1.0
1.9
—
—
—
0
0
6
28
2.15
0.91
4.7
4.8
5.25
4.86
kpa
—
6
28
6
28
2.15
0.91
4.7
4.8
9.28
9.27
kpa
—
6
28
20
281
0.68
0.88
2.2
1.6
—
—
—
0
0
20
136
1.50
0.87
2.7
3.6
72.65
162.18
mg/l
0.88
15
110
6
30
2.01
0.87
15.2
8.2
—
—
—
0
0
11
64
1.74
0.85
6.4
4.1
—
—
—
0
0
52
422
1.29
0.82
4.5
3.2
—
—
—
0
0
13
81
1.63
0.81
34.2
20.0
0.71
0.57
%
0.67
13
81
117
1047
1.23
0.79
8.4
11.6
—
—
—
0
0
165
1533
1.27
0.78
14.0
14.1
3.96
3.94
mmol/l
0.34
160
1468
32
244
1.35
0.77
2.2
1.6
—
—
—
0
0
5
23
2.18
0.76
1.6
2.0
—
—
—
0
0
16
227
0.68
0.75
1.7
1.9
—
—
—
0
0
5
26
1.93
0.70
2.8
3.2
—
250.53
—
0
6
14
93
1.53
0.69
2.1
2.7
5.19
5.27
pmol/l
0.11
14
84
5
92
0.53
0.68
1.0
1.1
—
—
—
0
0
18
243
0.71
0.66
1.6
1.9
—
—
—
0
0
5
28
1.79
0.66
2.0
2.8
11.86
12.28
umol/l
—
5
28
7
44
1.60
0.65
2.1
1.3
—
—
—
0
0
18
242
0.71
0.65
1.6
1.8
—
—
—
0
0
206
1984
1.46
0.64
16.2
17.6
280.33
274.44
e9/l
0.52
199
1872
5
29
1.73
0.63
1.0
1.0
—
—
—
0
0
18
241
0.72
0.63
1.6
1.9
—
—
—
0
0
206
1985
1.45
0.63
18.6
18.7
39.74
39.00
%
1.41
196
1918
12
173
0.67
0.62
2.7
2.0
—
—
—
0
0
79
693
1.20
0.62
4.8
3.4
0.00
0.00
estimate
—
8
120
11
71
1.56
0.61
1.4
3.3
—
—
—
0
0
0
19
0.00
0.60
0.0
1.4
—
21.00
—
0
5
0
19
0.00
0.60
0.0
1.4
—
19.83
—
0
6
0
19
0.00
0.60
0.0
8.7
—
—
—
0
0
121
1107
1.19
0.59
7.4
11.1
0.04
0.03
e9/l
0.63
102
889
206
1988
1.43
0.58
16.1
17.4
4.69
4.59
e12/l
2.46
198
1869
6
35
1.72
0.58
3.8
2.9
23.08
16.85
mmol/l
—
6
35
5
86
0.57
0.57
1.0
1.9
—
—
—
0
0
5
85
0.57
0.57
1.0
1.0
—
—
—
0
0
206
1989
1.42
0.57
16.2
17.5
7.04
6.89
e9/l
0.42
200
1870
6
36
1.67
0.57
1.0
1.1
—
—
—
0
0
9
59
1.53
0.55
1.9
1.6
0.42
0.70
g/l
—
9
50
121
1111
1.18
0.55
7.4
11.1
0.57
0.57
e9/l
0.01
102
893
9
60
1.51
0.55
21.8
19.9
—
—
—
0
0
119
1094
1.17
0.53
7.9
11.4
8.12
8.29
%
0.28
111
1051
78
693
1.18
0.52
6.4
5.0
0.00
0.00
estimate
—
8
123
9
64
1.41
0.51
37.2
23.3
—
—
—
0
0
7
45
1.56
0.49
2.1
1.3
5.72
6.25
g/l
—
7
38
7
45
1.56
0.49
2.1
1.3
0.48
0.40
g/l
—
7
36
7
45
1.56
0.49
2.1
1.3
1.56
2.28
g/l
—
7
38
78
698
1.17
0.48
4.9
3.4
0.00
0.00
estimate
—
8
121
24
190
1.28
0.48
2.2
2.1
13.22
15.47
ng/l
—
10
60
7
47
1.49
0.47
43.0
28.9
12.61
11.63
%
—
7
47
16
119
1.36
0.47
1.7
1.7
460.31
392.17
mu/l
0.39
16
114
7
50
1.40
0.45
9.9
8.5
29.59
93.38
g/mol
—
7
45
123
1143
1.15
0.45
7.5
11.0
36.38
36.19
%
0.06
115
1105
115
1064
1.15
0.44
7.4
11.4
0.54
0.62
%
0.94
107
1026
10
69
1.46
0.43
2.9
2.0
—
—
—
0
0
117
1086
1.15
0.43
7.6
11.3
2.76
3.19
%
1.15
109
1045
164
1560
1.17
0.42
8.4
9.4
25.35
24.08
u/l
0.34
158
1495
44
497
0.85
0.41
2.1
2.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.9
—
—
—
0
0
5
35
1.43
0.39
1.4
4.3
—
—
—
0
0
8
114
0.68
0.38
4.5
3.4
—
—
—
0
0
12
89
1.36
0.37
2.2
1.3
1.18
1.19
g/l
0.01
12
84
9
70
1.29
0.37
8.3
5.1
39.50
37.31
%
—
9
70
25
207
1.22
0.36
3.8
3.6
24.52
21.34
%
0.53
25
199
9
124
0.71
0.36
2.1
2.1
—
—
—
0
0
6
42
1.43
0.35
3.0
4.8
451.33
440.17
umol/l
—
6
42
122
1145
1.13
0.35
7.4
10.9
2.47
2.37
e9/l
0.39
107
954
11
81
1.36
0.35
7.4
4.8
14.82
15.69
%
0.09
11
81
12
154
0.76
0.35
2.6
1.8
133.00
153.50
u/ml
—
6
66
10
73
1.38
0.33
8.0
4.6
26.70
27.25
%
—
10
73
49
435
1.15
0.33
11.5
12.0
—
—
—
0
0
97
1022
0.89
0.32
4.6
4.3
—
—
—
0
0
119
1120
1.12
0.32
7.5
10.9
48.97
48.33
%
0.21
111
1079
29
248
1.18
0.31
1.7
1.9
—
—
—
0
0
15
119
1.27
0.31
2.3
1.4
—
—
—
0
0
7
54
1.29
0.30
1.1
1.5
—
—
—
0
0
7
55
1.27
0.30
1.9
4.9
—
—
—
0
0
76
808
0.90
0.29
2.4
1.8
1.47
1.45
g/l
0.07
40
395
97
906
1.11
0.29
2.8
2.0
5.32
5.29
mmol/l
0.09
86
820
9
115
0.77
0.28
2.3
2.0
—
—
—
0
0
10
76
1.32
0.27
7.9
4.8
67.70
68.32
%
—
10
76
10
76
1.32
0.27
7.9
4.8
14.50
9.04
%
—
10
76
60
549
1.11
0.26
1.5
1.6
—
—
—
0
0
44
395
1.13
0.26
3.2
2.3
—
—
—
0
0
30
262
1.16
0.26
2.3
6.8
5.52
2.48
mg/l
0.43
20
189
9
72
1.25
0.26
1.3
1.3
—
—
—
0
0
54
581
0.90
0.26
1.8
1.9
—
—
—
0
0
5
37
1.35
0.23
1.4
4.2
—
—
—
0
0
5
38
1.31
0.23
2.0
1.5
—
—
—
0
0
5
39
1.28
0.23
2.2
4.0
48.60
49.62
%
—
5
39
5
39
1.28
0.23
2.2
3.8
3.12
3.15
e9/l
—
5
39
21
181
1.17
0.21
4.8
2.5
5285.00
4499.48
u/l
—
7
49
0
11
0.00
0.21
0.0
1.2
—
33.88
—
0
11
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
32
286
1.13
0.21
4.5
5.0
—
—
—
0
0
53
489
1.10
0.20
2.3
3.5
2.59
2.57
mg/l
0.03
47
432
0
14
0.00
0.20
0.0
2.6
—
4.89
—
0
14
23
257
0.87
0.20
1.3
1.6
—
—
—
0
0
94
891
1.08
0.19
3.5
3.4
50.40
51.94
ug/l
0.06
88
840
6
52
1.15
0.19
1.5
1.3
—
—
—
0
0
6
52
1.15
0.19
1.5
1.3
—
—
—
0
0
7
57
1.22
0.18
2.3
1.1
—
233.35
—
0
17
7
58
1.20
0.18
43.7
24.9
76.14
71.21
%
—
7
58
34
308
1.11
0.18
1.4
1.6
—
—
—
0
0
46
424
1.10
0.18
8.2
9.6
—
—
—
0
0
5
65
0.76
0.17
1.0
1.2
—
—
—
0
0
112
1073
1.07
0.17
9.1
13.4
0.00
0.01
e9/l
0.49
91
777
15
171
0.86
0.17
1.6
2.4
—
—
—
0
0
8
68
1.17
0.16
5.1
3.6
1.25
1.24
mmol/l
—
8
58
36
386
0.91
0.16
3.1
3.3
560.93
606.14
mosm/kgh2o
0.64
28
332
17
191
0.87
0.16
2.0
4.2
3337.00
1222.69
ng/l
—
10
116
49
456
1.08
0.16
10.4
11.3
23.31
23.42
mmol/l
0.12
49
456
6
78
0.76
0.16
1.5
1.2
—
—
—
0
0
6
79
0.75
0.15
1.5
1.2
—
—
—
0
0
7
89
0.77
0.14
1.0
1.1
—
—
—
0
0
8
99
0.79
0.14
1.0
1.0
—
—
—
0
0
50
471
1.07
0.12
13.9
11.8
0.50
0.90
mmol/l
0.38
39
376
10
114
0.86
0.11
1.0
1.2
—
—
—
0
0
5
48
1.03
0.09
1.6
1.4
396.80
328.07
ug/g
—
5
27
6
53
1.13
0.09
1.0
1.2
—
—
—
0
0
6
53
1.13
0.09
1.5
1.4
—
—
—
0
0
6
54
1.10
0.09
1.7
4.0
—
—
—
0
0
54
556
0.95
0.09
4.1
4.5
—
—
—
0
0
7
68
1.02
0.08
1.0
6.8
—
—
—
0
0
6
70
0.85
0.08
1.2
1.1
—
—
—
0
0
25
233
1.07
0.07
5.4
5.2
8.51
8.56
g/l
0.02
25
225
8
74
1.07
0.07
1.4
1.6
—
—
—
0
0
98
992
0.96
0.07
5.0
3.8
35.80
132.54
e6/l
—
5
13
19
175
1.08
0.07
1.1
1.2
0.38
0.87
u/ml
0.56
13
134
22
232
0.93
0.07
1.9
1.5
192.00
591.76
titre
—
5
34
15
161
0.92
0.06
1.0
1.1
2.63
10.73
u/ml
—
6
49
36
344
1.04
0.05
6.0
4.4
1.06
1.11
inr
—
8
94
113
1105
1.03
0.05
4.6
4.4
7.01
7.39
mm/h
0.22
105
1023
16
149
1.07
0.04
1.2
1.5
—
—
—
0
0
12
110
1.09
0.04
1.4
1.4
—
—
—
0
0
31
317
0.96
0.03
1.6
1.8
—
—
—
0
0
69
695
0.98
0.03
5.7
5.4
110.45
57.27
e6/l
0.38
47
463
13
121
1.07
0.02
1.8
1.5
—
—
—
0
0
35
356
0.97
0.02
3.2
4.3
2.97
2.44
e6/l
0.23
21
210
55
536
1.02
0.02
15.9
15.1
24.66
24.86
mmol/l
0.23
55
536
55
554
0.98
0.02
4.1
4.6
0.16
0.25
e6/l
0.38
41
417
14
146
0.95
0.02
2.3
2.8
24.64
31.44
u/l
0.53
14
120
21
201
1.04
0.01
3.2
5.8
64.62
59.12
e9/l
0.26
11
124
36
364
0.98
0.01
1.6
1.7
—
—
—
0
0
84
840
0.99
0.01
3.2
2.6
2.73
2.61
mmol/l
0.81
78
789
33
321
1.02
0.00
4.3
2.9
—
—
—
0
0
40
391
1.02
0.00
4.5
3.4
6.47
7.94
e6/l
0.30
33
343
62
611
1.01
0.00
3.4
2.0
—
—
—
0
0
38
374
1.01
0.00
1.4
1.2
—
—
—
0
0
60
594
1.00
0.00
4.8
4.6
25.40
30.79
e6/l
0.21
46
452
84
836
0.99
0.00
3.2
2.6
1.34
1.41
mmol/l
0.97
79
788
87
859
1.01
0.00
3.6
2.8
4.27
4.29
mmol/l
0.06
82
819
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
0.23
—
0
6
7
72
0.96
-0.00
1.0
6.5
294.29
418.21
mg/l
—
7
72
5
49
1.01
-0.00
1.4
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.0
—
—
—
0
0
6
63
0.94
-0.00
1.0
6.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
879.44
—
0
9
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
51
0.97
-0.00
1.0
5.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2000.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
4.21
—
0
7
6
59
1.01
-0.00
1.5
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
14.3
—
92.57
—
0
7
0
5
0.00
-0.00
0.0
5.2
—
12.00
—
0
5

Mortality – FinRegistry

Association

Association between endpoint P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION and mortality.

Females

Parameter HR [95% CI] p-value
P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION 6.474 [4.98, 8.41] < 0.001
Birth year 0.997 [0.99, 1.0] 0.407

During the follow-up period (1.1.1998 — 31.12.2019), 71 out of 6317 females with P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION died.

Males

Parameter HR [95% CI] p-value
P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION 3.741 [2.92, 4.79] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 5727 males with P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION died.

Mortality risk

Mortality risk for people of age

years, who have P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION.

N-year risk Females Males
1 0.569% 0.49%
5 3.842% 3.819%
10 8.574% 10.069%
15 17.236% 18.695%
20 30.123% 31.154%

Relationships between endpoints

Index endpoint: P16_SLOW_FETAL_GROWTH_FETAL_MALNUTRITION – Slow fetal growth and fetal malnutrition

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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