brain aneurysm: A congenital or acquired aneurysm within the cranium.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
268 |
4. Check minimum number of eventsNone |
268 |
5. Include endpointsNone |
268 |
6. Filter based on genotype QC (FinnGen only) |
268 |
Control definitions (FinnGen only)
- Control exclude
- I9_CEREBVASC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- I67
- Name in latin
- Dissectio arteriae cerebralis sine ruptura
Similar endpoints
↥List of similar endpoints to
Dissection of cerebral arteries, nonruptured
based on the number of shared cases.
Similar with more cases:
- Cerebrovascular diseases
- Neurological diseases, wide definition
- Cardiovascular diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1673 | 729 | 931 |
| Only index persons | 1553 | 683 | 870 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 52.52 | 52.32 | 52.80 |
| Only index persons | 51.96 | 51.56 | 52.28 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 268 | 144 | 124 |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | 50.75 | 47.98 | 53.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 244
- Matched controls
- 2441
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I67.0
ICD-10 Finland
Dissection of cerebral arteries, nonruptured
+∞
323.0
243
*
B01AA03
ATC
warfarin; systemic
14.7
70.9
141
207
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
839.6
67.3
63
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
751.9
61.6
58
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
31.5
46.6
62
26
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
+∞
40.8
38
*
AA1AD
NOMESCO Finland
CT of head and brain
7.5
40.7
118
270
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
+∞
36.4
34
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
+∞
34.2
32
*
G90.2
ICD-10 Finland
Horner syndrome
+∞
28.7
27
*
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
315.8
28.4
28
*
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
17.9
23.7
37
24
XA800
NOMESCO Finland
Neuropsychological investigation
15.4
21.8
36
27
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
21.1
20
*
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
+∞
20.1
19
*
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
216.9
19.9
20
*
B01AC04
ATC
clopidogrel; oral
4.8
14.9
53
133
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
7.4
14.8
36
56
K90
ICPC
Stroke/cerebrovascular accident
56.8
14.0
16
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
13.7
13
*
PA6CG
NOMESCO Finland
Extensive MRI examination of neck vasculature with high intensity magnet
147.9
13.6
14
*
XF400
NOMESCO Finland
ECG with 12 standard connections
4.1
13.4
56
164
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
15.2
13.0
21
15
R51.80
ICD-10 Finland
Headache
3.8
12.9
61
199
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
136.7
12.6
13
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.3
12.0
47
129
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.1
11.8
38
85
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.9
11.7
39
91
I65.0
ICD-10 Finland
Occlusion and stenosis of vertebral artery
+∞
11.5
11
*
C10AA05
ATC
atorvastatin; oral
2.7
11.1
102
516
PA6AD
NOMESCO Finland
CT of neck arteries
29.5
10.8
14
5
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
13.8
10.8
18
14
R4150
NOMESCO Finland
Neuropsychological rehabilitation
114.7
10.5
11
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
+∞
10.5
10
*
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
+∞
10.5
10
*
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
34.2
10.4
13
*
H53.1
ICD-10 Finland
Subjective visual disturbances
5.6
9.8
28
55
PA7BD
NOMESCO Finland
CT angiography of neck and brain
22.8
9.5
13
6
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
9.4
9
*
PA7CC
NOMESCO Finland
Very extensive angiography of arteries of neck and brain
+∞
9.4
9
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
10.1
8.9
17
18
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
12.2
8.7
15
13
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
10.6
8.7
16
16
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
13.4
8.5
14
11
B01AB05
ATC
enoxaparin; parenteral
2.4
8.5
88
463
I72.0
ICD-10 Finland
Aneurysm and dissection of carotid artery
+∞
8.4
8
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.0
8.4
33
91
C09AA05
ATC
ramipril; oral
2.6
7.6
63
291
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
82.5
7.5
8
*
K99
ICPC
Cardiovascular disease other
9.8
7.4
14
15
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
+∞
7.3
7
*
I10
ICD-10 Finland
Essential (primary) hypertension
2.1
7.3
132
880
R42
ICD-10 Finland
Dizziness and giddiness
2.5
7.1
58
267
N02BE01
ATC
paracetamol; systemic, rectal
2.6
7.0
213
1765
R4120
NOMESCO Finland
Occupational therapy
4.3
6.7
24
61
N03AF02
ATC
oxcarbazepine; oral
6.5
6.6
16
26
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
71.6
6.5
7
*
I67.8
ICD-10 Finland
Other specified cerebrovascular diseases
71.6
6.5
7
*
C10AA01
ATC
simvastatin; oral
2.1
6.3
91
545
H53.4
ICD-10 Finland
Visual field defects
13.0
6.1
10
8
ZXA05
NOMESCO Finland
Left side
2.2
6.0
68
363
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
102
252
5.92
41.77
2.0
1.8
29.2
29.5
s
0.23
97
242
135
575
3.72
24.98
2.4
1.9
158.9
162.1
u/l
0.03
129
533
56
200
3.28
12.64
7.9
7.8
5.2
5.2
kpa
0.10
50
192
56
200
3.28
12.64
7.4
7.9
1.0
1.4
mmol/l
0.31
39
165
56
200
3.28
12.64
7.9
7.8
13.4
12.0
kpa
0.71
50
194
179
1201
2.48
11.01
6.0
4.2
6.1
6.6
mmol/l
4.95
168
1117
56
225
2.88
10.20
25.5
18.3
2.4
1.2
inr
—
6
35
15
24
6.56
9.09
1.1
1.1
3.3
2.9
u/ml
—
7
10
46
177
2.93
9.01
8.6
8.4
119.4
122.3
g/l
0.38
40
170
72
355
2.41
8.57
3.8
3.4
382.2
228.4
ng/l
0.34
48
259
11
7
16.30
7.29
1.6
2.4
—
—
—
0
0
28
91
3.32
7.25
7.2
10.6
24.6
25.0
mmol/l
0.29
28
82
33
121
2.97
7.00
7.3
8.9
0.7
0.7
%
0.09
33
121
138
955
1.92
6.37
8.6
6.2
1.2
1.2
mmol/l
1.05
116
809
39
165
2.60
6.33
3.3
2.7
68.1
74.4
ml/min/173m2
0.29
15
67
17
43
4.15
6.27
1.6
1.1
38.7
9.7
e6/l
0.36
12
33
127
865
1.89
6.07
7.8
5.2
1.2
1.2
mmol/l
1.22
114
793
31
122
2.74
5.78
7.4
8.6
1.7
1.5
%
0.27
31
122
10
17
6.07
5.67
1.1
1.1
100.6
93.8
%
—
10
17
60
323
2.10
5.59
2.9
2.5
1.3
1.0
e6/l
0.28
33
173
55
296
2.08
5.10
3.4
2.6
3.4
3.0
e6/l
0.06
29
149
28
113
2.65
4.98
9.6
7.1
24.1
24.4
mmol/l
0.18
22
107
104
705
1.78
4.77
3.8
2.8
—
—
—
0
0
11
25
4.55
4.60
1.1
1.1
—
—
—
0
0
252
2265
2.89
4.41
19.7
13.3
4.0
4.0
mmol/l
0.27
246
2218
251
2254
2.79
4.35
19.8
13.2
139.8
139.8
mmol/l
0.10
246
2208
83
545
1.76
4.15
3.5
2.7
0.3
0.3
e6/l
0.17
62
401
247
2216
2.46
4.02
17.6
12.0
21.0
22.5
mg/l
0.25
199
1699
69
434
1.79
3.98
2.1
2.0
2.9
3.2
mg/l
0.37
61
376
16
54
3.09
3.92
1.7
2.3
0.4
1.3
g/l
0.62
16
49
8
11
7.46
3.88
1.1
1.0
—
—
—
0
0
70
453
1.74
3.64
1.6
1.6
0.6
1.0
mg/l
1.90
49
353
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
9
7.95
3.58
1.1
1.3
—
—
—
0
0
43
244
1.91
3.41
3.5
2.2
22.0
23.3
%
0.28
37
217
190
1599
1.65
3.37
4.3
3.8
9.8
10.4
mm/h
0.23
185
1484
72
481
1.68
3.31
2.8
2.1
—
—
—
0
0
38
212
1.92
3.17
2.2
1.7
—
—
—
0
0
14
50
2.90
3.14
1.6
2.0
38.2
39.0
g/l
0.20
14
43
41
236
1.87
3.11
8.5
5.0
1.0
1.0
mmol/l
0.08
36
219
37
206
1.92
3.10
2.1
1.6
—
—
—
0
0
6
9
6.79
2.88
1.2
1.1
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
6
9
6.79
2.88
1.0
1.0
120.8
154.7
%
—
6
9
49
306
1.74
2.85
2.6
3.0
0.8
0.8
mmol/l
0.51
43
295
16
65
2.55
2.85
1.7
1.9
—
—
—
0
0
122
962
1.49
2.64
5.6
3.9
—
—
—
0
0
99
751
1.50
2.57
3.4
3.5
42.1
39.2
ng/l
0.04
60
477
5
7
7.25
2.56
1.2
1.3
—
—
—
0
0
59
402
1.60
2.46
1.3
1.3
38.6
32.4
iu/ml
0.17
19
137
254
2383
2.26
2.39
19.6
13.8
81.1
76.0
umol/l
0.78
254
2383
25
135
1.94
2.31
2.3
2.3
64.3
68.2
g/l
2.18
25
124
223
2019
1.62
2.30
5.0
4.4
1.7
2.4
mu/l
0.62
212
1861
14
60
2.41
2.26
5.6
3.3
3.8
4.0
mmol/l
0.72
14
55
240
2225
1.75
2.12
4.7
4.2
1.4
1.5
mmol/l
0.93
229
2071
180
1570
1.45
2.11
3.4
2.9
46.0
47.7
u/l
0.07
169
1491
234
2156
1.67
2.10
4.2
3.7
1.2
1.3
mmol/l
1.12
223
1996
38
242
1.66
2.07
9.4
6.7
—
—
—
0
0
7
20
3.56
2.07
1.1
1.1
—
—
—
0
0
98
771
1.43
2.03
2.0
1.8
89.9
96.3
pmol/l
0.71
51
411
14
64
2.25
1.98
1.3
2.8
—
—
—
0
0
45
303
1.58
1.97
2.2
1.7
—
—
—
0
0
106
853
1.40
1.91
5.5
4.5
35.8
36.3
g/l
0.44
99
803
243
2275
1.73
1.87
5.4
4.6
2.6
2.9
mmol/l
4.57
236
2115
186
1651
1.41
1.84
8.1
7.4
72.5
77.4
u/l
1.53
176
1563
5
12
4.22
1.83
1.4
1.3
—
—
—
0
0
239
2231
1.66
1.82
4.8
4.2
4.4
4.8
mmol/l
5.10
231
2090
222
2042
1.51
1.76
5.5
5.3
38.2
39.5
mmol/mol
1.40
215
1930
13
61
2.19
1.74
1.0
1.1
—
—
—
0
0
13
61
2.19
1.74
1.0
1.1
—
—
—
0
0
27
165
1.71
1.72
6.6
3.0
2.4
2.3
mmol/l
0.05
18
130
5
13
3.90
1.72
1.0
1.4
0.9
1.2
g/l
—
5
13
11
51
2.21
1.52
1.2
1.2
—
—
—
0
0
7
27
2.63
1.52
3.3
1.4
—
111.7
—
0
6
129
1102
1.33
1.51
5.7
6.3
10.5
11.1
umol/l
0.40
124
1055
141
1234
1.30
1.33
9.5
9.4
4.2
4.0
e9/l
0.40
127
1090
10
48
2.13
1.29
1.7
1.3
—
—
—
0
0
11
55
2.04
1.29
2.1
2.4
1.5
1.4
mg/l
0.09
11
50
6
25
2.43
1.25
1.2
1.1
—
—
—
0
0
6
25
2.43
1.25
1.2
1.1
—
—
—
0
0
223
2091
1.40
1.23
19.5
12.4
39.9
40.7
%
0.62
177
1633
81
665
1.31
1.21
2.2
2.5
60.8
55.2
u/l
0.63
73
611
68
545
1.33
1.20
3.4
3.1
1881.7
958.2
ng/l
0.75
60
453
82
677
1.30
1.17
2.7
3.4
2.3
2.3
mmol/l
0.30
74
606
68
547
1.33
1.17
2.8
2.5
12982.8
6349.7
umol/l
0.31
62
491
182
1663
1.29
1.17
4.2
3.8
14.6
14.7
pmol/l
0.05
174
1528
224
2111
1.37
1.12
14.8
11.1
83.9
84.3
ml/min/173m2
0.12
193
1755
17
265
0.62
1.12
1.5
1.7
—
—
—
0
0
11
59
1.90
1.09
2.8
1.3
—
—
—
0
0
50
389
1.35
1.07
1.3
1.3
1.2
10.4
u/ml
2.12
13
164
87
733
1.28
1.06
3.5
3.2
33.4
31.9
u/l
0.16
82
699
9
46
1.99
1.04
1.8
1.9
—
—
—
0
0
55
438
1.32
1.02
1.5
1.4
18.3
20.9
nmol/l
0.76
50
380
7
36
1.97
0.97
1.7
1.5
—
—
—
0
0
6
28
2.17
0.92
2.8
4.1
—
1096.2
—
0
6
6
28
2.17
0.92
1.0
1.1
—
—
—
0
0
226
2153
1.32
0.87
4.6
4.2
5.8
5.9
mmol/l
0.54
214
1995
117
1039
1.22
0.87
4.0
3.2
0.0
0.0
estimate
0.50
14
202
115
1021
1.22
0.86
4.1
3.2
0.0
0.0
estimate
0.00
14
209
6
31
1.96
0.85
1.3
1.2
—
—
—
0
0
6
33
1.84
0.79
1.8
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
17
115
1.51
0.79
1.1
1.3
—
—
—
0
0
11
67
1.67
0.76
1.2
1.4
179.7
269.6
miu/ml
—
6
36
115
1031
1.20
0.76
5.3
4.3
0.0
0.0
estimate
0.00
14
209
43
348
1.28
0.72
1.6
1.4
—
—
—
0
0
19
135
1.44
0.71
1.3
1.5
—
—
—
0
0
7
41
1.73
0.70
1.0
1.5
—
—
—
0
0
10
61
1.66
0.69
1.4
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
8
52
1.55
0.60
2.8
1.9
—
—
—
0
0
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
6
36
1.68
0.57
1.2
1.1
—
—
—
0
0
17
125
1.38
0.55
2.5
1.8
—
—
—
0
0
67
590
1.18
0.53
1.5
1.7
1.3
1.4
mmol/l
0.74
57
510
21
164
1.30
0.48
1.1
1.2
138.8
155.2
iu/ml
—
8
74
30
246
1.25
0.48
2.4
2.0
—
—
—
0
0
39
330
1.21
0.47
1.5
1.7
1213.1
1163.0
nmol/l
0.13
34
258
7
49
1.44
0.46
1.9
1.6
—
—
—
0
0
14
104
1.37
0.44
2.5
1.7
—
—
—
0
0
49
428
1.18
0.43
1.3
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.48
0.40
1.2
1.2
—
—
—
0
0
8
61
1.32
0.40
1.5
1.2
—
—
—
0
0
9
66
1.38
0.39
1.1
1.4
—
—
—
0
0
26
216
1.23
0.38
2.2
1.9
—
—
—
0
0
5
36
1.40
0.38
2.0
1.8
13.4
13.2
%
—
5
36
5
37
1.36
0.37
1.4
1.1
—
—
—
0
0
29
245
1.21
0.37
1.6
2.3
6.2
7.4
umol/l
0.35
22
215
5
76
0.65
0.36
2.2
1.8
—
—
—
0
0
64
582
1.13
0.34
4.2
4.2
19.7
21.3
%
0.38
25
259
6
45
1.34
0.34
1.8
1.5
—
—
—
0
0
6
46
1.31
0.33
2.0
1.5
—
—
—
0
0
6
46
1.31
0.33
2.0
1.5
—
—
—
0
0
6
46
1.31
0.33
2.0
1.5
—
—
—
0
0
44
391
1.15
0.32
1.5
1.8
411.4
435.4
pmol/l
0.35
39
340
13
101
1.30
0.32
2.9
1.7
—
—
—
0
0
7
98
0.71
0.31
5.0
1.7
—
—
—
0
0
24
206
1.18
0.27
2.9
3.0
—
—
—
0
0
5
38
1.32
0.23
1.2
1.2
30.3
14.9
u/l
—
5
33
51
470
1.11
0.22
1.2
1.3
0.5
2.2
u/ml
1.25
11
140
59
548
1.10
0.22
5.1
3.5
0.0
0.0
estimate
0.68
14
204
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
5
43
1.17
0.21
2.0
3.3
15.2
35.6
u/ml
—
5
43
89
846
1.08
0.20
2.2
2.3
82.8
75.7
nmol/l
0.97
83
766
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
7
60
1.17
0.18
1.1
1.1
—
—
—
0
0
16
183
0.87
0.16
1.8
2.3
0.2
0.2
g/l
0.34
16
173
9
79
1.14
0.15
1.7
1.5
—
—
—
0
0
42
447
0.93
0.13
2.6
2.9
0.6
0.7
ug/l
0.41
21
283
5
45
1.11
0.10
1.6
1.3
—
—
—
0
0
6
58
1.04
0.08
2.2
1.6
—
—
—
0
0
6
58
1.04
0.08
2.0
1.6
—
—
—
0
0
83
808
1.04
0.08
4.5
3.2
—
—
—
0
0
14
153
0.91
0.07
1.5
3.6
1.2
1.2
mmol/l
0.01
14
136
9
84
1.07
0.07
1.3
1.4
—
—
—
0
0
154
1519
1.03
0.07
3.8
3.1
—
—
—
0
0
75
731
1.04
0.07
4.4
4.6
1.5
2.3
ug/l
1.00
67
654
9
104
0.86
0.06
3.2
1.3
—
—
—
0
0
11
107
1.03
0.00
1.1
1.0
—
—
—
0
0
13
127
1.02
0.00
2.7
2.5
25.7
51.1
u/ml
0.62
13
122
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
5
56
0.89
0.00
1.0
1.3
—
1.7
—
0
10
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.6
—
222.7
—
0
7
0
6
0.00
0.00
0.0
7.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_DISCER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_DISCER | 1.628 [1.22, 2.17] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.506 |
During the follow-up period (1.1.1998 — 31.12.2019), 89 out of 624 females with I9_DISCER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_DISCER | 1.389 [1.11, 1.74] | 0.004 |
| Birth year | 0.99 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 128 out of 787 males with I9_DISCER died.
Mortality risk
Mortality risk for people of age
years, who have I9_DISCER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.099% | 0.298% |
| 5 | 0.878% | 1.694% |
| 10 | 2.544% | 4.33% |
| 15 | 4.874% | 8.115% |
| 20 | 8.809% | 14.239% |
Relationships between endpoints
↥Index endpoint: I9_DISCER – Dissection of cerebral arteries, nonruptured
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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