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Hypertrophy of tongue papillae

Endpoint Browser PheWeb

K11_HYPERTROPHY_TONGUE_PAPILLAE

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — K14.3
  • Hospital discharge: ICD-10 — K14.3
  • Hospital discharge: ICD-8 — 5293
  • Cause of death: ICD-10 — K14.3
  • Cause of death: ICD-8 — 5293

3 out of 7 registries used, show all original rules.

434

4. Check minimum number of events

None

434

5. Include endpoints

None

434

6. Filter based on genotype QC (FinnGen only)

434

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2799 1597 1191
Only index persons 2669 1527 1142
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.03
Only index persons 0.05 0.06 0.04
Median age at first event (years)
Whole population 55.06 55.67 54.28
Only index persons 55.73 56.39 54.85

-FinnGen-

Key figures

All Female Male
Number of individuals 434 263 171
Unadjusted period prevalence (%) 0.08 0.09 0.08
Median age at first event (years) 59.84 58.23 62.31

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
375
Matched controls
3748
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K14.31
ICD-10 Finland
Coated tongue
+∞
143.1
128
*
K14.30
ICD-10 Finland
Black hairy tongue
+∞
134.7
121
*
K14.39
ICD-10 Finland
Papillary hypertrophy of the tongue UNS
+∞
68.9
64
*
K14.38
ICD-10 Finland
Other papillary hypertrophy of the tongue
+∞
36.0
34
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
19.0
28.7
44
26
K14.3
ICD-10 Finland
Hypertrophy of tongue papillae
+∞
25.3
24
*
SAA02
NOMESCO Finland
Basic examination of mouth
2.8
17.9
282
1946
A07AA02
ATC
nystatin; oral
5.2
16.7
54
118
A01AB09
ATC
miconazole; local oral
4.1
14.5
60
168
D20
ICPC
Mouth/tongue/lip symptom/complaint
5.8
14.1
40
75
SAA01
NOMESCO Finland
Simple examination of mouth
2.5
13.6
289
2148
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
13.2
184
1105
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.2
12.5
207
1336
SAA03
NOMESCO Finland
Extended examination of mouth
2.2
12.4
175
1052
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.3
12.0
150
846
K02.1
ICD-10 Finland
Caries of dentine
2.2
11.7
234
1628
SFA10
NOMESCO Finland
Fillning on one surface of tooth
2.2
11.6
225
1540
K02.8
ICD-10 Finland
Other dental caries
7.9
10.8
24
32
K02.0
ICD-10 Finland
Caries limited to enamel
2.9
10.7
69
271
WX110
NOMESCO Finland
Local anesthesy
2.2
10.2
278
2139
Z01.2
ICD-10 Finland
Dental examination
2.1
10.2
176
1126
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.3
9.9
51
171
B37.0
ICD-10 Finland
Candidal stomatitis
9.5
9.6
19
21
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
3.0
9.5
57
210
SDA02
NOMESCO Finland
Parodonthologic therapy
2.1
9.5
145
872
EJB10
NOMESCO Finland
Excision of lesion of apex or body of tongue
22.4
9.4
13
6
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
2.0
9.0
231
1686
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
2.0
9.0
155
975
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.3
8.9
93
470
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.9
8.8
221
1598
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.9
8.8
195
1346
K14.1
ICD-10 Finland
Geographic tongue
20.6
8.5
12
6
J02AC01
ATC
fluconazole; systemic
2.0
8.5
158
1016
K14.32
ICD-10 Finland
Hypertrophy of papillae foliatae
+∞
8.4
8
*
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.9
8.3
176
1186
WZA90
NOMESCO Finland
Other doctors statement
2.2
8.3
100
540
A02BC05
ATC
esomeprazole; systemic
1.9
7.8
158
1044
R52.9
ICD-10 Finland
Pain, unspecified
3.1
7.7
43
151
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.0
7.7
119
707
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
7.7
121
728
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
18.8
7.6
11
6
C05AA08
ATC
fluocortolone; rectal, topical
2.5
7.5
62
277
D82
ICPC
Teeth/gum disease
1.9
7.4
138
878
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
6.0
7.3
19
33
SPAT1263
SPAT
Sampling
1.8
7.3
172
1187
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
5.0
7.3
22
46
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.8
7.0
159
1079
S18
ICPC
Laceration/cut
1.8
6.8
163
1123
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.9
6.8
114
695
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
6.7
139
911
SPAT1312
SPAT
General health counselling
1.9
6.7
124
785
SBA00
NOMESCO Finland
Microbiological examinations
6.4
6.5
16
26
A01AB04
ATC
amphotericin B; local oral
3.5
6.5
29
88
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
6.4
91
520
H02AB06
ATC
prednisolone; systemic
1.7
6.4
177
1270
N02BE01
ATC
paracetamol; systemic, rectal
2.0
6.2
318
2752
WX290
NOMESCO Finland
Other blockade of nerve
1.7
6.2
166
1175
K03.66
ICD-10 Finland
Tooth plaque
3.0
6.2
35
126
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
6.1
164
1159
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
6.1
54
252
SPAT1310
SPAT
Counselling related to known health issue
1.8
6.1
123
794

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
99
453
2.54
13.55
1.8
1.4
—
—
—
0
0
344
2660
2.41
12.67
5.2
4.0
13.4
11.7
mm/h
1.09
318
2446
217
1452
1.99
11.10
5.8
4.5
36.2
35.8
g/l
0.49
200
1365
257
1855
1.95
10.21
7.3
5.7
0.2
0.2
e9/l
0.26
228
1657
181
1171
1.94
9.91
7.1
5.4
—
—
—
0
0
241
1719
1.90
9.75
7.7
5.7
27.2
28.2
%
0.73
225
1619
238
1696
1.89
9.60
7.5
5.5
58.3
57.1
%
0.75
224
1607
253
1845
1.89
9.43
6.9
5.5
1.8
2.0
e9/l
0.84
224
1652
249
1807
1.89
9.42
7.0
5.4
0.0
0.0
e9/l
0.50
220
1584
275
2061
1.91
9.41
5.1
4.8
6.5
6.7
mmol/l
0.73
261
1910
234
1671
1.87
9.25
7.8
5.6
2.7
2.8
%
0.19
216
1569
340
2748
2.10
9.22
9.6
7.4
78.9
76.9
u/l
0.41
328
2578
246
1798
1.85
8.90
6.8
5.4
0.6
0.6
e9/l
1.85
218
1574
233
1679
1.84
8.78
8.2
5.8
8.6
8.5
%
0.09
217
1591
253
1870
1.85
8.78
6.8
6.3
10.8
11.0
umol/l
0.04
242
1775
163
1051
1.88
8.78
2.7
2.1
168.8
245.2
u/l
0.50
153
988
226
1614
1.84
8.77
8.0
5.6
0.6
0.7
%
0.44
209
1518
198
1372
1.81
8.36
7.1
8.3
1.2
1.2
inr
0.28
56
415
86
450
2.14
8.35
2.2
2.1
206.1
117.5
ug/g
0.45
65
354
312
2485
1.91
8.31
5.4
4.2
—
—
—
0
0
168
1125
1.80
7.82
3.6
2.4
56.2
56.3
u/l
0.02
157
1046
230
1702
1.75
7.48
9.3
6.7
1.2
1.2
mmol/l
0.01
190
1439
174
1190
1.77
7.46
4.3
3.3
2.4
2.4
mmol/l
0.01
142
1048
202
1445
1.74
7.38
2.7
2.0
—
—
—
0
0
88
488
2.01
7.25
1.3
1.2
—
—
—
0
0
383
3337
2.26
7.13
5.7
4.7
1.8
2.3
mu/l
0.68
354
3068
154
1029
1.77
7.08
5.0
3.8
—
—
—
0
0
87
486
1.99
7.01
1.4
1.3
397.3
454.5
titre
0.19
15
113
404
3608
2.73
7.01
20.0
13.3
20.4
22.4
mg/l
0.70
343
2830
16
36
4.58
6.76
3.6
1.4
286.4
283.1
mosm/kgh2o
0.21
16
23
138
917
1.74
6.35
4.5
4.0
—
—
—
0
0
265
2097
1.68
6.27
11.3
8.9
4.3
4.1
e9/l
1.21
239
1866
330
2786
1.77
5.99
4.6
3.9
14.9
14.8
pmol/l
0.19
303
2537
90
536
1.86
5.93
3.4
3.7
0.8
0.8
mmol/l
0.47
80
512
129
857
1.72
5.87
2.2
2.0
3.1
3.1
mg/l
0.06
112
753
208
1565
1.63
5.86
7.7
5.8
1.2
1.2
mmol/l
0.42
189
1413
123
814
1.71
5.65
1.3
1.2
2.1
1.9
u/ml
0.03
35
220
73
414
1.92
5.57
1.4
1.3
—
—
—
0
0
233
1818
1.61
5.55
4.0
3.6
0.0
0.0
estimate
0.50
52
335
133
905
1.68
5.49
7.6
6.6
—
—
—
0
0
74
427
1.88
5.36
8.6
5.3
1.1
1.0
mmol/l
0.45
67
402
182
1353
1.59
5.21
4.6
3.6
32.2
38.2
ng/l
0.31
126
937
97
619
1.73
5.02
1.3
1.3
3.4
12.8
u/ml
2.38
36
250
44
217
2.14
4.92
1.3
1.2
259.9
260.1
u/ml
0.00
35
196
226
1783
1.56
4.91
3.8
3.5
0.0
0.0
estimate
0.00
49
350
97
624
1.71
4.87
1.7
1.7
1195.0
1236.0
nmol/l
0.15
73
483
145
1051
1.57
4.49
2.7
3.1
270.3
109.4
e6/l
0.27
120
809
225
1796
1.52
4.49
5.4
4.8
0.0
0.0
estimate
0.50
54
351
70
421
1.79
4.42
2.2
1.6
—
—
—
0
0
144
1048
1.56
4.36
2.7
2.9
—
—
—
0
0
97
645
1.65
4.26
1.4
1.3
37.3
40.6
iu/ml
0.07
23
201
106
724
1.61
4.18
1.8
1.7
457.7
443.5
pmol/l
0.23
81
600
182
1404
1.51
4.18
2.5
1.9
99.7
96.4
pmol/l
0.46
100
733
102
694
1.61
4.08
2.7
2.7
549.1
561.3
mosm/kgh2o
0.18
92
590
133
965
1.55
4.03
2.9
3.0
0.3
0.4
e6/l
0.30
109
722
209
1672
1.48
3.95
4.5
4.0
—
—
—
0
0
107
743
1.58
3.92
1.4
1.4
2.2
2.4
g/l
0.62
57
455
57
335
1.81
3.89
1.5
1.4
—
—
—
0
0
22
90
2.52
3.78
3.0
2.9
1.8
1.5
mg/l
0.54
22
83
397
3675
1.94
3.74
21.7
15.4
139.6
139.7
mmol/l
0.25
390
3579
367
3324
1.67
3.70
6.3
5.6
39.7
39.5
mmol/mol
0.13
345
3125
411
3857
2.24
3.63
13.6
10.1
26.8
26.4
u/l
0.17
402
3725
397
3683
1.91
3.59
21.6
15.5
4.0
4.0
mmol/l
0.20
389
3582
104
733
1.55
3.55
2.3
2.4
5.9
5.9
e6/l
0.02
95
648
41
229
1.87
3.30
1.2
1.2
—
—
—
0
0
110
798
1.51
3.26
1.7
1.7
1.2
1.2
mg/l
0.02
78
619
91
635
1.55
3.23
2.8
2.9
2.5
2.4
mmol/l
0.38
78
564
160
1252
1.44
3.23
3.3
3.6
44.5
75.5
e6/l
0.89
128
880
380
3505
1.68
3.18
5.2
4.4
5.9
5.9
mmol/l
0.10
346
3227
16
61
2.69
3.17
2.0
1.3
—
—
—
0
0
11
34
3.29
3.08
1.8
1.3
—
—
—
0
0
132
1007
1.45
3.02
3.4
3.1
—
—
—
0
0
22
101
2.24
2.98
4.2
5.0
—
—
—
0
0
46
276
1.75
2.95
6.0
4.4
0.4
0.4
%
0.01
16
66
45
269
1.75
2.92
7.0
4.6
0.0
0.1
%
0.66
17
72
23
109
2.17
2.90
1.8
2.1
283.8
675.5
ug/l
0.43
23
102
113
845
1.46
2.85
5.6
4.5
—
—
—
0
0
77
533
1.54
2.82
4.0
2.3
14.5
13.5
umol/l
0.21
71
492
68
458
1.57
2.81
3.9
2.3
24.0
22.7
%
0.15
60
399
31
167
1.92
2.80
5.1
3.7
—
—
—
0
0
141
1102
1.41
2.79
2.7
2.3
—
—
—
0
0
194
1601
1.38
2.79
12.1
9.1
0.0
0.0
e9/l
0.63
168
1328
119
903
1.44
2.77
2.5
2.6
346.1
6314.1
umol/l
3.45
96
793
421
4033
2.47
2.77
29.5
19.6
255.3
251.4
e9/l
0.58
415
3939
5
6
8.41
2.75
1.0
1.0
—
—
—
0
0
45
274
1.72
2.75
2.5
2.6
10.0
10.7
g/l
0.57
37
247
421
4036
2.44
2.71
29.3
19.5
4.5
4.5
e12/l
1.17
413
3935
63
421
1.58
2.69
30.3
19.8
1.1
1.3
inr
—
8
58
421
4037
2.43
2.69
29.4
19.6
7.0
6.7
e9/l
3.39
414
3936
74
514
1.53
2.67
1.7
2.1
30.2
29.6
s
0.36
67
501
52
333
1.64
2.64
6.3
4.1
—
—
—
0
0
126
974
1.41
2.64
3.9
3.8
0.0
0.0
estimate
0.80
54
346
39
231
1.76
2.63
1.6
2.5
—
—
—
0
0
37
216
1.78
2.62
1.4
1.3
—
34.6
—
0
15
26
135
1.98
2.61
7.1
4.2
—
—
—
0
0
134
1054
1.39
2.53
5.6
3.7
7.4
7.4
ph
0.52
25
204
11
39
2.87
2.49
1.1
1.1
—
—
—
0
0
29
160
1.87
2.46
2.1
1.7
—
—
—
0
0
61
415
1.55
2.42
6.7
6.7
105.2
104.2
mmol/l
0.98
61
402
121
943
1.39
2.39
3.0
2.9
—
—
—
0
0
37
223
1.72
2.36
6.9
6.5
—
—
—
0
0
50
327
1.60
2.35
2.9
1.8
367.6
366.3
nmol/l
0.02
45
302
22
112
2.02
2.35
3.1
2.0
276.7
3567.8
u/l
—
8
42
59
402
1.54
2.33
2.5
2.6
6.2
7.6
umol/l
0.43
50
354
63
436
1.52
2.32
1.3
1.2
—
—
—
0
0
43
272
1.64
2.31
1.3
1.4
—
—
—
0
0
21
107
2.01
2.24
2.2
1.4
361.7
309.0
ug/g
0.46
13
64
51
341
1.56
2.19
8.0
9.2
96.3
95.7
%
0.48
51
330
44
284
1.61
2.19
8.0
4.5
0.1
0.1
%
0.56
17
84
381
3585
1.51
2.13
5.0
4.4
4.6
4.7
mmol/l
0.74
359
3348
12
49
2.49
2.12
1.4
1.6
71.2
60.2
%
0.87
12
49
46
303
1.58
2.11
7.7
4.4
0.7
0.9
%
0.17
18
94
398
3783
1.63
2.10
20.1
12.4
—
—
—
0
0
133
1073
1.35
2.09
3.7
3.1
6.9
7.6
mmol/l
1.21
110
895
386
3647
1.53
2.06
5.4
4.8
2.7
2.8
mmol/l
0.58
360
3387
29
170
1.76
2.06
2.4
2.5
—
—
—
0
0
15
70
2.18
2.00
1.3
1.2
—
—
—
0
0
38
243
1.62
1.98
2.4
2.5
—
12.3
—
0
12
21
113
1.90
1.95
1.4
1.2
—
—
—
0
0
44
293
1.56
1.94
1.2
1.2
—
—
—
0
0
47
318
1.54
1.93
8.4
9.5
115.9
122.2
g/l
1.09
47
309
124
1003
1.33
1.90
3.3
3.2
1262.7
188.8
mg/l
0.67
76
637
8
28
2.89
1.87
1.0
1.2
—
—
—
0
0
186
1596
1.29
1.84
3.5
2.7
130.6
120.2
ug/l
0.23
170
1486
378
3573
1.45
1.83
4.9
4.3
1.5
1.5
mmol/l
0.56
353
3325
51
356
1.49
1.83
4.6
4.6
4.8
18.2
ug/l
0.61
43
303
7
23
3.08
1.80
1.0
1.1
—
—
—
0
0
129
1059
1.31
1.77
4.3
4.0
7.9
8.4
mg/mmol
0.06
82
650
105
837
1.34
1.77
1.7
1.5
20.0
21.2
nmol/l
0.35
88
713
99
784
1.34
1.74
4.4
3.8
1.0
1.0
kg/l
0.63
16
112
53
377
1.46
1.74
7.8
8.8
11.9
12.3
kpa
0.22
53
367
53
377
1.46
1.74
7.8
8.8
5.1
5.1
kpa
0.11
53
366
40
269
1.54
1.71
3.0
2.8
76.1
71.6
e9/l
0.41
32
215
53
379
1.45
1.69
7.8
8.8
1.5
1.1
mmol/l
0.28
47
303
366
3455
1.38
1.65
4.3
3.9
1.3
1.3
mmol/l
0.05
341
3205
43
297
1.50
1.63
3.2
3.5
—
—
—
0
0
67
504
1.39
1.63
1.9
2.1
—
—
—
0
0
36
241
1.54
1.58
2.4
3.5
126.2
203.8
ng/l
1.13
29
217
101
818
1.31
1.52
3.7
3.6
—
—
—
0
0
44
312
1.46
1.48
3.2
3.3
—
—
—
0
0
32
212
1.55
1.48
11.2
9.0
25.3
24.3
mmol/l
0.82
32
200
45
321
1.45
1.47
4.1
3.4
—
—
—
0
0
19
111
1.74
1.41
7.9
3.5
3.8
3.9
mmol/l
0.20
19
101
38
265
1.48
1.40
5.9
8.3
—
—
—
0
0
7
29
2.44
1.39
1.1
1.2
—
—
—
0
0
43
309
1.43
1.37
1.6
1.4
—
—
—
0
0
29
192
1.55
1.36
1.4
2.7
0.2
0.2
e6/l
0.06
29
185
116
970
1.27
1.36
1.8
1.6
1.4
1.4
mmol/l
0.28
99
824
21
128
1.67
1.36
2.2
2.8
—
—
—
0
0
21
128
1.67
1.36
7.1
3.8
1.1
1.4
mmol/l
1.65
21
123
13
232
0.55
1.34
1.8
1.4
—
—
—
0
0
34
236
1.48
1.29
1.8
2.3
4.1
4.0
e9/l
0.06
24
189
271
2498
1.23
1.26
4.3
3.7
—
—
—
0
0
11
56
1.99
1.23
2.7
2.8
4.1
4.0
mmol/l
0.43
11
56
11
56
1.99
1.23
2.7
2.8
—
—
—
0
0
11
56
1.99
1.23
2.7
2.8
104.5
105.8
mmol/l
0.61
11
56
8
37
2.18
1.22
1.1
1.1
—
—
—
0
0
30
206
1.49
1.21
1.5
1.2
—
—
—
0
0
5
20
2.52
1.15
1.0
1.1
—
—
—
0
0
36
261
1.41
1.12
6.2
3.4
98.9
76.7
ng/l
0.54
30
230
49
375
1.35
1.11
3.0
2.7
1.9
1.8
%
0.47
44
346
12
66
1.84
1.10
1.5
2.5
18.4
15.5
%
—
5
32
13
74
1.78
1.08
3.5
2.9
3.3
2.9
mmol/l
—
7
48
25
170
1.50
1.07
2.7
2.5
1.2
1.2
%
0.01
25
170
78
640
1.27
1.07
4.4
3.8
905.7
263.1
ng/l
0.65
60
496
81
668
1.26
1.07
2.3
1.9
—
—
—
0
0
19
122
1.58
1.04
1.5
1.6
—
—
—
0
0
117
1008
1.22
1.04
5.3
5.1
1.8
2.8
ug/l
1.33
112
905
5
22
2.29
1.03
19.0
13.8
1468.4
1713.8
nmol/l
—
5
22
5
22
2.29
1.03
15.0
11.4
1230.0
896.6
nmol/l
—
5
22
5
22
2.29
1.03
1.0
2.1
—
—
—
0
0
38
283
1.38
1.02
2.5
2.6
3.5
6.8
ug/l
1.80
31
254
9
48
1.89
1.01
3.0
2.9
—
—
—
0
0
11
61
1.82
0.99
1.1
1.1
—
—
—
0
0
16
100
1.62
0.98
1.3
1.2
—
2.7
—
0
16
7
36
1.96
0.97
1.1
1.3
—
—
—
0
0
12
69
1.76
0.97
3.4
3.1
54.4
57.4
%
0.36
12
69
52
412
1.30
0.95
2.1
1.5
—
—
—
0
0
31
228
1.39
0.91
1.5
1.6
1.0
1.5
g/l
1.68
26
208
20
135
1.50
0.91
5.1
1.5
—
—
—
0
0
20
135
1.50
0.91
5.2
1.5
—
—
—
0
0
24
169
1.44
0.89
8.5
12.4
—
—
—
0
0
8
42
1.92
0.89
1.6
1.6
—
—
—
0
0
13
79
1.67
0.89
7.4
2.2
—
—
—
0
0
20
136
1.49
0.88
5.2
1.5
—
—
—
0
0
11
64
1.74
0.87
1.6
1.3
200.6
257.7
u/ml
—
5
32
8
44
1.83
0.86
4.3
1.8
33.0
33.3
pg
—
8
44
6
32
1.89
0.82
2.3
1.2
—
—
—
0
0
34
260
1.33
0.81
1.1
1.3
185.2
125.4
iu/ml
0.25
13
110
12
74
1.64
0.79
1.5
5.5
—
—
—
0
0
13
82
1.60
0.79
1.2
1.2
4.2
3.8
mmol/l
0.89
13
76
6
34
1.78
0.76
1.3
2.9
—
—
—
0
0
18
124
1.47
0.76
5.6
1.5
—
—
—
0
0
33
254
1.32
0.76
2.1
2.2
10.2
12.6
nmol/l
0.65
28
233
19
133
1.45
0.75
5.4
1.5
—
—
—
0
0
5
24
2.10
0.74
1.8
1.6
1.2
1.0
g/l
—
5
24
29
377
0.75
0.74
1.3
1.3
—
—
—
0
0
5
25
2.01
0.73
1.6
1.2
—
—
—
0
0
9
56
1.62
0.72
1.1
1.0
—
—
—
0
0
11
68
1.63
0.72
2.3
2.6
—
—
—
0
0
7
41
1.72
0.70
10.7
3.5
—
—
—
0
0
7
41
1.72
0.70
2.3
2.5
—
—
—
0
0
11
69
1.61
0.69
3.1
3.0
—
—
—
0
0
25
188
1.35
0.68
4.3
3.7
—
—
—
0
0
66
563
1.20
0.67
2.0
1.5
—
—
—
0
0
30
234
1.30
0.65
4.7
2.5
—
—
—
0
0
11
71
1.56
0.62
1.9
1.2
—
—
—
0
0
98
871
1.16
0.62
5.0
3.6
94.7
92.2
%
0.42
92
858
5
30
1.67
0.61
1.2
1.1
—
—
—
0
0
14
197
0.70
0.60
1.6
1.7
—
—
—
0
0
16
114
1.42
0.59
1.5
1.3
—
—
—
0
0
15
106
1.43
0.58
6.5
1.5
—
—
—
0
0
6
35
1.72
0.58
1.2
1.7
—
—
—
0
0
18
133
1.37
0.56
6.1
8.5
1.8
1.6
%
0.32
18
127
14
99
1.43
0.54
1.2
1.2
—
—
—
0
0
17
125
1.37
0.54
2.9
3.3
0.2
0.1
g/l
—
8
46
112
1016
1.14
0.54
1.5
1.4
—
—
—
0
0
11
74
1.50
0.54
2.7
1.4
—
—
—
0
0
10
66
1.53
0.53
1.4
1.2
—
—
—
0
0
9
65
1.39
0.51
1.7
3.2
—
—
—
0
0
10
67
1.50
0.50
3.4
2.8
3.9
4.4
e9/l
—
10
67
19
145
1.32
0.49
1.1
1.2
—
—
—
0
0
7
45
1.56
0.49
1.4
2.5
—
—
—
0
0
315
3049
1.12
0.47
22.6
16.2
13.8
13.6
%
1.28
308
3007
43
367
1.19
0.46
2.0
1.7
—
—
—
0
0
7
51
1.38
0.44
1.3
1.2
—
—
—
0
0
8
56
1.44
0.42
1.5
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
17
132
1.30
0.41
6.4
8.7
0.9
0.9
%
0.05
17
127
43
372
1.17
0.40
1.6
1.4
—
—
—
0
0
340
3317
1.12
0.40
20.1
13.9
38.8
40.1
%
1.38
223
2438
5
37
1.36
0.37
1.8
2.7
—
—
—
0
0
9
70
1.29
0.37
9.8
13.1
10.9
11.4
mmol/l
—
9
65
9
70
1.29
0.37
9.8
13.1
106.6
106.2
mmol/l
—
9
65
6
43
1.40
0.35
1.3
1.2
—
—
—
0
0
21
172
1.23
0.35
8.0
9.9
24.8
24.6
mmol/l
0.09
21
161
6
46
1.31
0.33
1.7
1.8
—
—
—
0
0
124
1313
0.92
0.30
3.5
2.8
—
—
—
0
0
8
66
1.22
0.27
1.7
3.0
—
—
—
0
0
9
73
1.24
0.25
1.1
1.9
—
—
—
0
0
30
264
1.15
0.25
1.5
1.4
—
—
—
0
0
9
75
1.20
0.25
5.9
3.6
18.8
27.9
u/ml
—
9
75
13
158
0.82
0.24
1.1
1.1
—
—
—
0
0
5
41
1.22
0.22
1.2
1.6
—
—
—
0
0
5
41
1.22
0.22
1.2
1.6
—
—
—
0
0
5
41
1.22
0.22
1.2
1.6
—
—
—
0
0
5
41
1.22
0.22
1.2
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
5.5
—
40.4
—
0
10
13
108
1.21
0.20
3.4
3.1
—
—
—
0
0
44
404
1.10
0.20
1.7
1.7
—
—
—
0
0
12
144
0.83
0.20
1.1
1.1
—
—
—
0
0
6
49
1.23
0.20
1.3
1.2
—
—
—
0
0
6
49
1.23
0.20
1.8
1.4
—
—
—
0
0
6
50
1.20
0.20
1.8
1.2
—
—
—
0
0
7
58
1.21
0.18
12.4
1.8
—
—
—
0
0
9
80
1.13
0.15
1.7
1.1
—
—
—
0
0
9
83
1.09
0.14
2.8
2.0
—
—
—
0
0
10
84
1.19
0.14
1.6
3.3
7.5
7.9
kpa
—
10
76
5
47
1.06
0.09
1.2
1.3
—
—
—
0
0
11
98
1.13
0.07
1.3
1.1
—
—
—
0
0
9
104
0.86
0.06
1.6
1.3
—
—
—
0
0
60
584
1.03
0.05
3.1
3.0
0.6
0.8
ug/l
1.52
48
379
10
95
1.05
0.00
9.4
11.5
1.5
1.3
mmol/l
—
10
87
13
125
1.04
0.00
7.2
10.1
—
—
—
0
0
6
66
0.91
0.00
1.7
1.2
—
—
—
0
0
6
60
1.00
0.00
1.3
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
7
76
0.92
0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
3.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
5.4
—
—
—
0
0
9
97
0.93
0.00
1.9
1.2
11.5
10.8
u/l
—
9
81
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
0.00
1.6
1.5
—
—
—
0
0
7
79
0.88
0.00
1.7
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
6
64
0.94
0.00
1.2
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
6.1
—
0
6
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
6
60
1.00
0.00
1.3
1.1
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint K11_HYPERTROPHY_TONGUE_PAPILLAE and mortality.

Females

Parameter HR [95% CI] p-value
K11_HYPERTROPHY_TONGUE_PAPILLAE 1.156 [0.89, 1.5] 0.272
Birth year 0.998 [0.99, 1.01] 0.573

During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 1269 females with K11_HYPERTROPHY_TONGUE_PAPILLAE died.

Males

Parameter HR [95% CI] p-value
K11_HYPERTROPHY_TONGUE_PAPILLAE 1.423 [1.07, 1.89] 0.014
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 126 out of 937 males with K11_HYPERTROPHY_TONGUE_PAPILLAE died.

Mortality risk

Mortality risk for people of age

years, who have K11_HYPERTROPHY_TONGUE_PAPILLAE.

N-year risk Females Males
1 0.14% 0.29%
5 0.731% 1.595%
10 1.941% 4.474%
15 3.717% 8.043%
20 6.267% 13.1%

Relationships between endpoints

↥

Index endpoint: K11_HYPERTROPHY_TONGUE_PAPILLAE – Hypertrophy of tongue papillae

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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