No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
486 |
4. Check minimum number of eventsNone |
486 |
5. Include endpointsNone |
486 |
6. Filter based on genotype QC (FinnGen only) |
473 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF7
Hypertrophy of tongue papillae
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2799 | 1597 | 1191 |
| Only index persons | 2669 | 1527 | 1142 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 55.06 | 55.67 | 54.28 |
| Only index persons | 55.73 | 56.39 | 54.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 473 | 289 | 184 |
| Unadjusted period prevalence (%) | 0.10 | 0.10 | 0.08 |
| Median age at first event (years) | 60.05 | 58.05 | 63.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 486
- Matched controls
- 4860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K14.31
ICD-10 Finland
Coated tongue
+∞
182.1
163
*
K14.30
ICD-10 Finland
Black hairy tongue
+∞
173.7
156
*
K14.39
ICD-10 Finland
Papillary hypertrophy of the tongue UNS
+∞
95.0
88
*
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
26.7
83.6
59
25
K14.38
ICD-10 Finland
Other papillary hypertrophy of the tongue
+∞
47.7
45
*
A07AA02
ATC
nystatin; oral
5.5
32.5
68
139
K14.3
ICD-10 Finland
Hypertrophy of tongue papillae
+∞
31.6
30
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.7
24.8
227
1197
D20
ICPC
Mouth/tongue/lip symptom/complaint
4.9
24.0
56
125
SAA02
NOMESCO Finland
Basic examination of mouth
3.1
23.9
382
2641
SBA00
NOMESCO Finland
Microbiological examinations
8.5
22.0
29
36
A01AB09
ATC
miconazole; local oral
3.7
21.2
74
224
SAA01
NOMESCO Finland
Simple examination of mouth
2.9
19.0
396
2937
Z01.2
ICD-10 Finland
Dental examination
2.3
18.6
263
1630
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
17.7
249
1531
SAA03
NOMESCO Finland
Extended examination of mouth
2.3
17.3
231
1385
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.2
16.9
270
1738
K02.1
ICD-10 Finland
Caries of dentine
2.3
16.6
326
2275
K13.78
ICD-10 Finland
Other change in the oral mucosa
6.4
16.6
28
46
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
6.0
16.5
30
53
K02.0
ICD-10 Finland
Caries limited to enamel
2.6
16.2
119
546
WX110
NOMESCO Finland
Infiltration anesthesia
2.4
15.4
377
2845
B37.0
ICD-10 Finland
Candidal stomatitis
14.6
15.2
25
18
SFA10
NOMESCO Finland
One-surface restoration
2.2
15.2
301
2077
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
2.2
15.1
299
2060
K14.1
ICD-10 Finland
Geographic tongue
58.6
14.9
17
*
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.4
14.7
128
633
K02.8
ICD-10 Finland
Other dental caries
6.0
14.6
26
45
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
14.4
164
908
SDA03
NOMESCO Finland
Periodontal treatment
2.1
13.9
226
1430
K03.66
ICD-10 Finland
Tooth plaque
3.3
13.7
55
181
K03.64
ICD-10 Finland
Dental calculus supragingival
2.1
13.4
180
1058
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.1
13.3
175
1020
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
2.0
13.2
265
1801
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
2.0
13.1
240
1575
EJB10
NOMESCO Finland
Excision of tumor or other lesion of apex or body of tongue
29.3
13.0
17
6
SXC05
NOMESCO Finland
Other oral or dental procedure
3.5
12.9
46
140
SFA20
NOMESCO Finland
Two-surface restoration
2.1
12.7
312
2265
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
12.3
195
1208
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
4.6
12.1
29
66
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
11.7
149
851
WZA90
NOMESCO Finland
Other medical or dental certificate
2.1
11.6
140
782
SDA02
NOMESCO Finland
Periodontal treatment, brief
2.0
11.6
196
1238
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
11.6
126
677
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.6
11.6
71
296
K14.32
ICD-10 Finland
Hypertrophy of papillae foliatae
+∞
11.5
11
*
D82
ICPC
Teeth/gum disease
1.9
11.2
202
1299
J02AC01
ATC
fluconazole; systemic
1.9
10.9
215
1424
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.4
10.7
78
352
A02BC02
ATC
pantoprazole; systemic
2.0
10.7
336
2584
SCA01
NOMESCO Finland
Preventive oral health care, short
2.0
10.4
161
979
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.5
10.4
74
331
SDA04
NOMESCO Finland
Demanding periodontal treatment
2.0
10.3
151
901
SPAT1263
SPAT
Sampling
1.9
10.0
220
1495
A01AB04
ATC
amphotericin B; local oral
3.3
10.0
38
121
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
12.5
9.9
17
14
S18
ICPC
Laceration/cut
1.8
9.7
235
1643
A02BC05
ATC
esomeprazole; systemic
1.8
9.5
208
1406
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
9.3
107
582
SFA30
NOMESCO Finland
Three-surface restoration
1.8
9.2
219
1514
E0000UV, ,
ATC
1.8
9.0
212
1459
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
8.9
226
1590
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
8.7
121
704
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.3
8.7
33
105
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.9
8.7
139
848
WX290
NOMESCO Finland
Other blockage of nerve
1.8
8.5
241
1744
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.4
8.4
61
274
A02BA02
ATC
ranitidine; systemic
2.0
8.4
101
558
M54.5
ICD-10 Finland
Low back pain
1.8
8.3
179
1194
SFA00
NOMESCO Finland
Small restoration
2.2
8.3
78
392
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
4.5
8.2
20
46
UJF30
NOMESCO Finland
Ileoscopy through colon
2.4
8.1
58
259
C05AA08
ATC
fluocortolone; rectal, topical
2.2
8.1
75
374
B37.08
ICD-10 Finland
Other candidal stomatitis
12.0
8.1
14
12
J01FF01
ATC
clindamycin; systemic
1.8
8.1
143
896
R20.2
ICD-10 Finland
Paraesthesia of skin
2.8
8.1
42
160
H02AB06
ATC
prednisolone; systemic
1.7
8.0
233
1689
K59.0
ICD-10 Finland
Constipation
2.9
7.9
38
139
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.8
7.9
143
903
F45.8
ICD-10 Finland
Other somatoform disorders
2.6
7.8
45
181
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
7.8
99
556
UJF32
NOMESCO Finland
Coloscopy
1.9
7.8
128
784
D19
ICPC
Teeth/gum symptom/complaint
1.8
7.7
148
949
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.0
7.7
35
124
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.9
7.7
125
762
P01AB01
ATC
metronidazole; oral, rectal
1.7
7.6
204
1441
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
7.4
56
257
D07AC01
ATC
betamethasone; topical
1.7
7.4
175
1192
H92.0
ICD-10 Finland
Otalgia
2.8
7.3
37
139
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
7.3
165
1107
D10.12
ICD-10 Finland
Bone tumor of the tip of the tongue
+∞
7.3
7
*
SPAT1153
SPAT
Removal of sutures
1.7
7.2
157
1043
A02BC03
ATC
lansoprazole; oral
1.8
7.1
142
920
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.8
7.1
138
887
SPAT1312
SPAT
General health counselling
1.7
7.1
160
1073
K08.80
ICD-10 Finland
Toothache NOS
2.4
7.1
49
216
KMAK, ,
NOMESCO Finland
1.7
7.0
251
1900
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
7.0
91
514
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.8
7.0
35
131
K10.00
ICD-10 Finland
Torus mandibularis
9.5
6.8
13
14
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
6.8
151
1005
D10.19
ICD-10 Finland
Benign tumor of the tongue UNS
40.6
6.8
8
*
L57.0
ICD-10 Finland
Actinic keratosis
2.3
6.7
54
254
R03BA01
ATC
beclometasone; inhalant
2.0
6.7
73
388
L82
ICD-10 Finland
Seborrhoeic keratosis
1.9
6.6
95
555
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
6.6
68
354
L17
ICPC
Foot/toe symptom/complaint
1.7
6.6
147
980
N30.0
ICD-10 Finland
Acute cystitis
2.0
6.6
80
442
J45
ICD-10 Finland
Asthma
2.2
6.5
54
257
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.2
6.5
58
285
N02AX02
ATC
tramadol; systemic, rectal
1.6
6.5
204
1487
K14.9
ICD-10 Finland
Disease of tongue, unspecified
70.7
6.4
7
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
6.4
211
1552
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
3.4
6.3
22
66
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
6.3
74
404
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.2
6.2
53
255
S29
ICPC
Skin symptom/complaint other
1.8
6.2
98
589
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
6.2
91
535
H02AB04
ATC
methylprednisolone; systemic
2.0
6.2
74
406
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
6.2
92
543
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.2
6.2
51
243
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.3
6.1
48
223
J01DB01
ATC
cefalexin; oral
1.8
6.1
399
3473
R42
ICD-10 Finland
Dizziness and giddiness
1.8
6.1
107
664
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
6.0
197
1442
M79.6
ICD-10 Finland
Pain in limb
1.6
6.0
201
1479
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
37
41
9.69
30.73
1.3
1.2
—
—
—
0
0
384
2961
2.41
14.23
5.3
4.0
13.15
11.52
mm/h
1.16
356
2732
245
1598
2.08
13.88
5.6
4.5
36.42
35.83
g/l
1.02
227
1506
104
512
2.31
11.83
2.3
2.2
191.90
113.38
ug/g
0.51
81
407
272
1912
1.96
11.78
8.1
5.7
27.79
28.14
%
0.20
257
1814
269
1890
1.95
11.60
7.8
5.5
57.94
57.15
%
0.50
255
1794
377
3063
2.03
9.62
9.3
7.4
78.14
76.79
u/l
0.29
364
2877
301
2276
1.85
9.54
5.0
4.7
6.45
6.70
mmol/l
1.47
287
2111
246
1753
1.82
9.44
14.3
12.5
1.15
1.21
inr
0.67
71
540
179
1159
1.86
9.37
2.6
2.1
166.15
247.59
u/l
0.62
169
1091
330
2583
1.86
9.19
5.2
4.2
7.60
1273.31
e6/l
—
5
36
279
2078
1.80
9.12
6.5
6.2
10.85
10.89
umol/l
0.01
266
1973
60
263
2.46
8.75
1.9
1.4
—
—
—
0
0
302
2321
1.80
8.70
11.2
9.0
4.25
4.07
e9/l
0.74
273
2064
191
1291
1.79
8.51
4.0
3.3
2.36
2.36
mmol/l
0.01
161
1151
430
3732
2.32
8.33
5.7
4.7
1.81
2.21
mu/l
0.66
400
3431
255
1881
1.75
8.33
9.1
6.6
1.22
1.22
mmol/l
0.05
211
1596
454
4042
2.87
8.24
19.2
13.1
20.02
22.31
mg/l
0.91
381
3156
185
1252
1.77
8.13
3.5
2.4
55.69
59.74
u/l
0.46
173
1167
373
3115
1.85
7.51
4.6
3.9
14.81
14.76
pmol/l
0.14
346
2839
143
915
1.80
7.50
1.4
1.3
2.28
1.84
u/ml
0.16
40
247
145
934
1.79
7.42
2.2
2.0
3.04
3.12
mg/l
0.14
125
818
263
2012
1.67
7.07
3.9
3.5
0.00
0.01
estimate
0.50
56
376
232
1719
1.67
7.06
7.3
5.8
1.21
1.22
mmol/l
0.24
210
1562
337
2765
1.71
6.83
3.7
2.9
44.86
44.35
u/l
0.05
313
2600
124
791
1.76
6.45
1.8
1.5
—
—
—
0
0
82
463
1.93
6.30
8.2
5.3
1.07
1.04
mmol/l
0.30
75
436
256
1982
1.62
6.28
3.9
3.5
0.00
0.00
estimate
0.50
59
417
219
1634
1.62
6.25
2.9
2.2
77.92
76.83
nmol/l
0.24
196
1462
52
250
2.21
6.14
1.3
1.2
238.86
256.74
u/ml
0.05
43
229
108
676
1.77
5.96
1.3
1.3
3.24
12.48
u/ml
2.67
39
274
255
1990
1.59
5.93
5.3
4.7
0.00
0.00
estimate
0.50
58
392
21
64
3.38
5.93
1.3
1.1
—
—
—
0
0
200
1484
1.59
5.70
4.4
3.5
30.46
36.58
ng/l
0.34
136
1022
107
677
1.74
5.66
1.7
1.7
1168.00
1221.50
nmol/l
0.22
82
527
188
1380
1.59
5.58
3.2
3.0
—
—
—
0
0
162
1151
1.61
5.49
2.8
3.0
245.70
115.36
e6/l
0.23
133
882
152
1064
1.62
5.47
2.8
3.2
1142.43
1058.68
ng/l
0.13
119
908
205
1541
1.57
5.47
2.5
1.9
99.56
96.52
pmol/l
0.41
119
798
109
702
1.71
5.40
1.3
1.3
35.59
39.41
iu/ml
0.10
25
228
93
574
1.77
5.35
2.3
2.0
—
—
—
0
0
150
1053
1.61
5.32
2.8
2.9
0.31
0.36
e6/l
0.21
123
794
82
491
1.81
5.21
2.1
2.2
—
—
—
0
0
204
1544
1.55
5.21
3.9
3.6
—
—
—
0
0
96
604
1.73
5.16
3.3
3.6
0.83
0.82
mmol/l
0.09
87
579
46
229
2.11
5.00
1.6
1.4
—
—
—
0
0
75
449
1.79
4.76
2.1
2.1
—
—
—
0
0
118
809
1.61
4.53
1.8
1.7
452.20
10879725.97
pmol/l
0.50
93
671
117
801
1.61
4.51
2.3
2.3
6.55
5.78
e6/l
0.21
112
720
95
625
1.65
4.29
2.4
2.7
1.00
0.97
e6/l
0.05
57
359
445
4116
1.96
4.22
20.7
15.0
139.65
139.69
mmol/l
0.14
438
4007
410
3712
1.67
4.08
6.2
5.5
39.53
39.46
mmol/mol
0.05
387
3489
445
4126
1.93
4.04
20.6
15.1
3.95
3.97
mmol/l
0.38
437
4011
125
893
1.54
3.97
1.7
1.7
1.15
1.17
mg/l
0.05
89
690
89
589
1.63
3.91
3.7
2.3
14.67
13.50
umol/l
0.31
83
549
100
681
1.59
3.91
2.7
2.9
2.46
2.45
mmol/l
0.31
85
608
24
101
2.45
3.88
3.2
2.9
1.81
1.53
mg/l
0.48
24
93
460
4327
2.18
3.81
13.5
10.0
26.90
26.45
u/l
0.18
450
4178
54
319
1.78
3.60
3.0
2.7
62.95
66.14
ml/min/173m2
0.25
22
138
78
510
1.63
3.59
3.6
2.3
23.87
22.75
%
0.14
67
443
227
1870
1.40
3.32
2.8
2.5
—
—
—
0
0
28
137
2.11
3.23
2.0
2.1
—
—
—
0
0
28
138
2.09
3.18
2.1
1.9
—
—
—
0
0
473
4533
2.62
3.16
28.6
19.3
255.98
251.78
e9/l
0.70
466
4428
424
3931
1.62
3.14
5.2
4.4
5.92
5.90
mmol/l
0.07
389
3618
24
112
2.20
3.12
1.3
1.2
—
2.75
—
0
16
473
4536
2.60
3.10
28.5
19.3
4.48
4.51
e12/l
0.77
464
4423
26
126
2.12
3.08
1.9
2.1
257.54
610.65
ug/l
0.46
26
118
415
3839
1.55
2.98
15.2
12.0
83.08
82.96
ml/min/173m2
0.04
358
3151
73
492
1.57
2.97
1.7
1.6
1.58
1.50
%
0.40
64
430
23
108
2.19
2.95
1.2
1.1
8.28
7.86
u/ml
—
5
14
140
1079
1.42
2.94
4.0
3.7
0.00
0.01
estimate
0.80
58
387
26
129
2.07
2.91
2.2
2.3
—
—
—
0
0
36
202
1.84
2.86
1.5
1.8
—
—
—
0
0
120
908
1.43
2.78
1.7
1.5
20.42
21.06
nmol/l
0.17
103
774
15
60
2.55
2.72
1.2
1.1
0.83
1.67
u/ml
—
8
28
42
251
1.74
2.72
2.0
1.8
—
—
—
0
0
82
580
1.50
2.68
2.4
2.9
2.37
2.23
e6/l
0.07
44
317
114
864
1.42
2.61
4.3
3.7
1.01
1.02
kg/l
0.86
19
118
471
4534
2.26
2.59
28.4
19.3
40.40
40.39
%
0.02
446
4272
80
569
1.49
2.55
1.7
2.1
30.26
29.57
s
0.40
73
555
59
393
1.57
2.54
1.8
1.9
—
—
—
0
0
24
123
2.00
2.50
1.4
1.2
—
—
—
0
0
23
116
2.03
2.50
2.1
1.4
342.71
312.65
ug/g
0.23
14
70
120
925
1.39
2.48
2.6
2.3
—
—
—
0
0
59
396
1.56
2.46
1.8
1.9
—
—
—
0
0
65
446
1.53
2.46
2.5
2.6
6.22
7.43
umol/l
0.42
55
388
211
1779
1.33
2.45
3.5
2.7
124.57
119.81
ug/l
0.11
195
1655
39
236
1.71
2.44
4.5
4.0
1.88
1.88
mmol/l
0.00
33
178
37
221
1.73
2.42
1.8
1.3
—
—
—
0
0
7
17
4.16
2.36
2.3
2.9
38314.29
35670.88
ug/l
—
7
17
128
1005
1.37
2.36
2.7
2.6
347.66
6299.72
umol/l
3.89
106
891
34
200
1.75
2.35
1.1
1.0
—
—
—
0
0
9
28
3.25
2.31
1.1
1.0
—
—
—
0
0
25
134
1.91
2.31
2.8
2.1
276.65
4196.96
u/l
—
8
56
26
142
1.88
2.28
1.5
1.6
—
—
—
0
0
70
497
1.48
2.26
4.7
4.4
32.60
32.16
%
0.12
52
335
27
150
1.85
2.25
3.3
2.0
—
—
—
0
0
427
4026
1.50
2.25
5.0
4.3
4.62
4.70
mmol/l
0.79
403
3766
296
2638
1.31
2.23
3.3
3.1
—
—
—
0
0
433
4097
1.52
2.21
5.4
4.8
2.74
2.79
mmol/l
0.52
406
3812
69
492
1.47
2.18
8.9
6.6
—
—
—
0
0
7
19
3.72
2.16
1.0
1.6
—
—
—
0
0
50
334
1.55
2.14
3.9
3.2
0.96
1.98
mmol/l
0.85
44
265
425
4011
1.47
2.14
4.9
4.3
1.45
1.48
mmol/l
0.72
397
3736
23
124
1.90
2.10
1.4
1.2
—
—
—
0
0
54
369
1.52
2.10
2.9
1.8
378.27
363.37
nmol/l
0.24
49
343
41
263
1.61
2.08
2.3
3.5
114.73
195.48
ng/l
1.40
33
236
90
680
1.40
2.08
1.4
1.4
—
—
—
0
0
92
698
1.39
2.08
4.0
3.8
813.67
311.38
ng/l
0.54
67
536
33
201
1.69
2.04
2.1
1.7
—
—
—
0
0
20
104
1.96
2.03
2.3
2.4
0.00
0.05
g/l
0.50
20
98
412
3880
1.41
1.97
4.3
3.9
1.28
1.28
mmol/l
0.02
384
3599
147
1210
1.31
1.94
3.8
3.1
7.07
7.56
mmol/l
0.79
122
1022
20
107
1.91
1.89
1.4
1.4
—
—
—
0
0
22
122
1.84
1.87
4.2
2.9
—
—
—
0
0
144
1189
1.30
1.85
4.2
3.8
10.91
9.09
mg/mmol
0.17
88
735
43
289
1.54
1.82
1.1
1.2
173.30
154.09
iu/ml
0.08
14
122
54
382
1.47
1.80
4.4
4.6
4.68
17.50
ug/l
0.61
44
319
50
349
1.48
1.78
8.1
9.2
116.52
122.17
g/l
0.98
50
342
18
96
1.91
1.73
2.4
2.4
0.00
0.00
g/l
-0.00
18
91
5
13
3.87
1.72
4.4
1.4
—
—
—
0
0
11
48
2.32
1.71
1.0
1.1
—
—
—
0
0
18
97
1.89
1.68
2.4
2.4
0.00
0.00
g/l
-0.00
18
91
19
106
1.82
1.61
1.6
1.3
—
—
—
0
0
35
233
1.54
1.57
10.9
8.5
25.35
24.50
mmol/l
0.75
35
221
23
138
1.70
1.54
1.3
1.4
—
—
—
0
0
41
284
1.48
1.53
2.3
2.2
11.19
12.91
nmol/l
0.49
36
260
16
86
1.89
1.52
2.6
1.8
4.29
5.06
mmol/24h
0.49
16
74
11
51
2.18
1.51
1.0
1.1
—
—
—
0
0
56
415
1.39
1.48
7.6
8.6
1.52
1.17
mmol/l
0.30
50
338
56
415
1.39
1.48
7.6
8.5
11.89
12.17
kpa
0.20
56
402
56
415
1.39
1.48
7.6
8.5
5.10
5.14
kpa
0.11
56
401
31
205
1.55
1.44
1.8
2.6
0.19
0.18
e6/l
0.06
31
197
23
142
1.65
1.41
7.0
3.6
1.06
1.40
mmol/l
1.81
23
135
7
29
2.43
1.39
1.1
1.3
—
—
—
0
0
13
67
1.97
1.39
1.5
1.4
—
—
—
0
0
13
67
1.97
1.39
1.5
1.4
—
—
—
0
0
9
41
2.22
1.37
1.2
1.2
2.53
2.95
ug/l
—
9
34
14
75
1.89
1.35
3.2
3.1
55.29
57.81
%
0.34
14
75
9
42
2.16
1.34
1.1
1.1
—
—
—
0
0
26
389
0.65
1.34
1.8
1.7
—
—
—
0
0
19
113
1.71
1.33
1.4
1.2
—
—
—
0
0
40
286
1.43
1.30
6.1
3.4
98.97
75.88
ng/l
0.67
34
255
17
99
1.74
1.29
1.0
1.2
—
—
—
0
0
23
146
1.60
1.28
2.2
3.3
3747.56
1845.08
u/ml
0.27
18
121
14
77
1.84
1.26
1.4
1.3
—
—
—
0
0
42
307
1.40
1.22
2.4
2.6
3.59
7.01
ug/l
2.06
35
277
5
19
2.65
1.22
1.2
1.4
—
—
—
0
0
5
19
2.65
1.22
1.2
3.0
3237.00
690.95
u/ml
—
5
19
18
109
1.68
1.20
1.3
1.1
—
—
—
0
0
47
352
1.37
1.19
3.1
2.4
28.57
31.35
u/l
0.51
40
306
12
64
1.90
1.19
1.2
1.3
—
—
—
0
0
12
64
1.90
1.19
1.2
1.4
—
—
—
0
0
12
64
1.90
1.19
1.3
1.4
—
—
—
0
0
8
38
2.12
1.19
2.5
2.2
—
—
—
0
0
12
65
1.87
1.14
1.2
1.4
—
—
—
0
0
12
65
1.87
1.14
1.2
1.4
—
—
—
0
0
12
65
1.87
1.14
1.3
1.4
—
—
—
0
0
8
40
2.02
1.12
1.0
1.1
—
94.40
—
0
5
126
1084
1.22
1.11
1.8
1.6
1.42
1.38
mmol/l
0.17
108
915
8
41
1.97
1.09
3.0
3.4
—
—
—
0
0
129
1115
1.21
1.08
5.2
4.9
1.75
2.67
ug/l
1.42
124
1001
15
90
1.69
1.05
1.2
1.2
4.10
3.76
mmol/l
0.87
15
83
5
22
2.29
1.03
5.8
2.0
—
—
—
0
0
5
22
2.29
1.03
5.8
2.0
—
—
—
0
0
11
60
1.85
1.03
2.7
2.8
104.45
105.75
mmol/l
0.60
11
60
11
60
1.85
1.03
2.7
2.8
4.12
4.00
mmol/l
0.47
11
60
25
173
1.47
0.99
2.8
2.5
0.72
0.65
%
0.68
25
173
5
23
2.19
0.98
5.8
1.9
—
—
—
0
0
5
23
2.19
0.98
1.6
1.3
—
—
—
0
0
5
23
2.19
0.98
1.6
1.3
—
—
—
0
0
6
28
2.16
0.92
16.5
16.7
1390.33
1710.43
nmol/l
—
6
28
6
28
2.16
0.92
13.2
13.7
1141.67
911.68
nmol/l
—
6
28
51
405
1.29
0.91
3.4
3.1
—
—
—
0
0
6
29
2.08
0.89
1.0
1.1
—
—
—
0
0
8
43
1.87
0.87
4.0
2.0
—
—
—
0
0
11
65
1.71
0.83
1.3
1.6
—
—
—
0
0
12
73
1.66
0.82
3.2
2.7
3.87
4.46
e9/l
0.63
12
73
12
74
1.64
0.79
1.5
2.5
18.42
15.56
%
—
5
35
16
108
1.50
0.74
2.1
4.4
—
2.37
—
0
13
10
60
1.68
0.72
1.3
1.6
—
—
—
0
0
12
76
1.59
0.72
1.2
1.5
—
—
—
0
0
9
57
1.59
0.71
1.2
1.5
—
—
—
0
0
9
58
1.56
0.70
1.7
1.1
—
—
—
0
0
5
27
1.86
0.68
1.8
1.5
1.15
1.04
g/l
—
5
27
5
27
1.86
0.68
1.4
1.1
—
—
—
0
0
5
28
1.79
0.66
5.8
1.8
—
—
—
0
0
5
28
1.79
0.66
5.8
1.8
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
15
103
1.47
0.65
2.6
2.4
0.32
0.35
u/ml
—
8
53
7
44
1.60
0.65
4.4
1.7
—
—
—
0
0
7
44
1.60
0.65
4.4
1.7
—
—
—
0
0
7
44
1.60
0.65
4.4
1.7
—
—
—
0
0
19
138
1.39
0.63
1.4
1.4
—
—
—
0
0
15
104
1.46
0.63
1.3
1.3
—
—
—
0
0
11
71
1.56
0.62
1.6
1.3
200.60
249.85
u/ml
—
5
34
8
49
1.64
0.62
4.1
1.9
—
—
—
0
0
14
96
1.47
0.62
3.4
1.7
—
—
—
0
0
5
30
1.67
0.61
1.4
1.8
—
—
—
0
0
368
3556
1.14
0.61
21.5
15.5
14.83
14.82
%
0.02
361
3512
0
22
0.00
0.59
0.0
2.5
—
—
—
0
0
0
22
0.00
0.59
0.0
2.5
—
—
—
0
0
10
64
1.57
0.59
1.7
1.5
—
—
—
0
0
99
884
1.15
0.58
4.5
4.3
20.56
20.70
%
0.03
49
414
8
55
1.46
0.56
1.0
1.0
—
—
—
0
0
9
61
1.48
0.54
1.8
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
3.9
—
—
—
0
0
0
15
0.00
0.41
0.0
3.9
—
—
—
0
0
8
59
1.36
0.41
1.1
1.3
—
—
—
0
0
13
97
1.35
0.40
1.8
1.6
—
—
—
0
0
9
66
1.37
0.38
1.4
1.1
—
—
—
0
0
19
152
1.26
0.37
5.8
7.9
1.75
1.58
%
0.29
19
143
5
37
1.35
0.37
1.0
1.7
—
—
—
0
0
5
37
1.35
0.37
1.2
1.1
—
—
—
0
0
10
72
1.40
0.37
3.6
1.7
—
—
—
0
0
10
73
1.38
0.34
3.5
1.7
—
—
—
0
0
10
73
1.38
0.34
3.5
1.7
—
—
—
0
0
6
46
1.31
0.33
1.2
1.2
—
—
—
0
0
13
101
1.30
0.32
3.0
1.7
—
—
—
0
0
7
52
1.35
0.31
1.1
1.1
—
—
—
0
0
7
96
0.73
0.31
1.4
1.6
—
—
—
0
0
22
184
1.20
0.31
1.2
1.3
35.65
26.87
iu/l
0.48
17
158
10
76
1.32
0.28
2.3
2.0
198.50
225.10
pmol/l
—
10
71
13
105
1.24
0.25
1.3
1.3
—
—
—
0
0
11
88
1.26
0.22
1.5
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
24.23
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
410.14
—
0
7
8
68
1.18
0.16
2.4
1.9
—
—
—
0
0
12
103
1.17
0.14
1.3
1.5
—
—
—
0
0
12
103
1.17
0.14
1.3
1.5
—
—
—
0
0
12
103
1.17
0.14
1.3
1.5
—
—
—
0
0
12
103
1.17
0.14
1.3
1.5
—
—
—
0
0
18
199
0.90
0.12
1.4
1.5
—
—
—
0
0
12
106
1.14
0.10
1.6
1.5
—
—
—
0
0
5
47
1.06
0.09
1.2
1.6
—
—
—
0
0
5
47
1.06
0.09
1.2
1.6
—
—
—
0
0
5
48
1.04
0.09
2.4
2.0
12.40
13.20
%
—
5
48
7
84
0.83
0.07
1.1
1.7
—
—
—
0
0
8
92
0.87
0.07
1.5
2.0
—
—
—
0
0
18
170
1.06
0.04
1.2
2.0
—
—
—
0
0
65
658
0.99
0.01
3.0
2.9
0.59
0.74
ug/l
1.43
52
425
12
116
1.04
0.00
1.4
1.5
—
—
—
0
0
12
121
0.99
0.00
1.6
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
2.2
—
1.28
—
0
9
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
6
64
0.94
0.00
1.2
1.2
—
2.68
—
0
19
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
55
0.91
-0.00
1.2
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
57.54
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint K11_HYPERTROPHY_TONGUE_PAPILLAE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_HYPERTROPHY_TONGUE_PAPILLAE | 1.156 [0.89, 1.5] | 0.272 |
| Birth year | 0.998 [0.99, 1.01] | 0.573 |
During the follow-up period (1.1.1998 — 31.12.2019), 117 out of 1269 females with K11_HYPERTROPHY_TONGUE_PAPILLAE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_HYPERTROPHY_TONGUE_PAPILLAE | 1.423 [1.07, 1.89] | 0.014 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 126 out of 937 males with K11_HYPERTROPHY_TONGUE_PAPILLAE died.
Mortality risk
Mortality risk for people of age
years, who have K11_HYPERTROPHY_TONGUE_PAPILLAE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.14% | 0.29% |
| 5 | 0.731% | 1.595% |
| 10 | 1.941% | 4.474% |
| 15 | 3.717% | 8.043% |
| 20 | 6.267% | 13.1% |
Relationships between endpoints
↥Index endpoint: K11_HYPERTROPHY_TONGUE_PAPILLAE – Hypertrophy of tongue papillae
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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