No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
581 |
4. Check minimum number of eventsNone |
581 |
5. Include endpointsNone |
581 |
6. Filter based on genotype QC (FinnGen only) |
566 |
Control definitions (FinnGen only)
- Control exclude
- G6_HYDROCEPH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- G91
- Name in latin
- Hydrocephalia obstructiva
Similar endpoints
↥List of similar endpoints to
Obstructive hydrocephalus
based on the number of shared cases.
Similar with more cases:
- Hydrocephalus
- Other neurological diseases
- Neurological diseases
- Neurological diseases, wide definition
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5759 | 2782 | 2921 |
| Only index persons | 4149 | 2069 | 2080 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | 0.08 |
| Only index persons | 0.08 | 0.08 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 50.19 | 53.09 | 47.07 |
| Only index persons | 46.90 | 51.02 | 42.81 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 566 | 293 | 273 |
| Unadjusted period prevalence (%) | 0.11 | 0.10 | 0.13 |
| Median age at first event (years) | 55.47 | 52.37 | 58.80 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 581
- Matched controls
- 5810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G91.1
ICD-10 Finland
Obstructive hydrocephalus
+∞
307.7
545
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
+∞
299.8
261
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
+∞
186.8
169
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
2374.6
181.1
166
*
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
+∞
173.9
158
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
12.6
171.8
205
241
AA1AD
NOMESCO Finland
CT of head and brain
9.1
159.5
374
962
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
+∞
153.1
140
*
AA1AA
NOMESCO Finland
Head X-ray examination
62.1
151.5
85
16
AAF00
NOMESCO Finland
Ventriculostomy
881.5
144.6
136
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
15.8
134.3
126
100
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
40.4
110.2
68
19
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
7.5
95.0
165
292
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
+∞
90.0
84
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
+∞
88.9
83
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.3
83.6
84
73
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
896.8
81.5
78
*
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
+∞
75.7
71
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
31.4
74.0
49
17
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
8.5
73.2
104
145
ZXD05
NOMESCO Finland
Urgent procedure
4.5
71.1
303
1133
AAF50
NOMESCO Finland
Third ventriculostomy
+∞
65.9
62
*
N03AX14
ATC
levetiracetam; systemic
11.7
61.4
66
63
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
29.3
60.7
41
15
AAF15
NOMESCO Finland
Ventriculoatrial shunt
+∞
60.5
57
*
3314A
ICD-9 Finland
Other cerebral degenerations, Obstructive hydrocephalus
+∞
57.2
54
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
11.8
53.8
57
53
XA800
NOMESCO Finland
Neuropsychological investigation
7.5
53.7
83
126
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.3
53.5
178
538
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
49.7
177
559
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
13.0
49.4
49
41
G91.8
ICD-10 Finland
Other hydrocephalus
+∞
45.4
43
*
R51.80
ICD-10 Finland
Headache
3.8
41.3
163
546
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
5.1
41.0
97
221
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
13.6
37.7
36
28
N03AF02
ATC
oxcarbazepine; oral
7.9
37.0
53
73
ZXE10
NOMESCO Finland
More than one and less than three hours
3.0
36.9
287
1428
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.9
36.6
59
93
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.5
36.4
163
588
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
13.3
35.2
34
27
ZXC86
NOMESCO Finland
Use of endoscopic device
81.3
34.3
38
5
2132
FHL
Ventricular operators sunt
+∞
33.7
32
*
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
12.5
31.0
31
26
N03AG01
ATC
valproic acid; systemic, rectal
4.9
30.9
74
169
AA1BD
NOMESCO Finland
Extensive CT of head and brain
8.7
30.7
40
49
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
30.3
214
989
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
10.6
30.3
34
34
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
10.0
30.0
35
37
XCK00
NOMESCO Finland
Perimetry
4.8
28.4
68
155
N18
ICPC
Paralysis/weakness
8.9
28.2
36
43
K90
ICPC
Stroke/cerebrovascular accident
7.2
27.5
42
62
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
6.6
27.5
46
75
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.9
27.4
65
147
AAA20
NOMESCO Finland
Insertion of intraventricular pressure monitoring device
283.5
27.0
27
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
8.6
26.8
35
43
H47.2
ICD-10 Finland
Optic atrophy
76.0
26.0
29
*
N03AB02
ATC
phenytoin; systemic
9.8
25.5
30
32
ZXD35
NOMESCO Finland
Usual procedure
6.4
25.5
44
74
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.9
25.3
81
230
R42
ICD-10 Finland
Dizziness and giddiness
2.7
24.5
174
794
2133
FHL
Suntin revisio
+∞
24.1
23
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
24.1
122
464
L28
ICPC
Limited function/disability (L)
2.9
23.8
141
585
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
+∞
23.1
22
*
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
+∞
23.1
22
*
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
7.5
22.7
33
46
N28
ICPC
Limited function/disability (N)
8.9
22.1
28
33
Q03.0
ICD-10 Finland
Malformations of aqueduct of Sylvius
+∞
22.0
21
*
Z2445
NOMESCO Finland
Psychologist
4.3
21.7
59
148
SPAT1229
SPAT
Assessment of need for aid
3.8
21.6
71
205
H02AB02
ATC
dexamethasone; systemic
3.1
20.7
95
340
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
20.4
71
213
N03AF01
ATC
carbamazepine; oral, rectal
4.3
20.2
55
138
G97.2
ICD-10 Finland
Intracranial hypotension following ventricular shunting
+∞
19.9
19
*
H53.4
ICD-10 Finland
Visual field defects
7.7
19.7
28
38
TAB00
NOMESCO Finland
Lumbar puncture
4.4
19.6
52
128
A28
ICPC
Limited function/disability NOS
2.6
19.2
133
592
2130
FHL
Ventricular atrial shunt
+∞
18.9
18
*
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
7.6
18.8
27
37
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
18.5
155
754
N29
ICPC
Neurological sympt/complt other
7.4
18.4
27
38
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
26.0
18.4
25
10
D33.07
ICD-10 Finland
Colloid coast in cerebral ventricle
185.4
17.6
18
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
7.6
17.5
25
34
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.7
17.1
57
166
D33.30
ICD-10 Finland
Acoustic neuroma
26.5
17.0
23
9
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
92.8
16.6
18
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.9
16.6
89
346
Z3229
NOMESCO Finland
Other healthcare associate professional
3.0
16.0
75
270
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
7.1
15.8
24
35
AAA10
NOMESCO Finland
Biopsy through craniotomy
+∞
15.7
15
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.7
15.6
37
83
H53.2
ICD-10 Finland
Diplopia
4.9
15.6
35
75
P20
ICPC
Memory disturbance
2.6
14.7
98
424
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.9
14.7
74
277
H02AB09
ATC
hydrocortisone; systemic
4.9
14.6
33
71
G91
ICD-10 Finland
Hydrocephalus
+∞
14.6
14
*
G81.1
ICD-10 Finland
Spastic hemiplegia
+∞
14.6
14
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
14.4
130
646
ZXA00
NOMESCO Finland
Right side
2.1
14.3
178
1006
C71.90
ICD-10 Finland
Malignant tumor in unspecified localization in the brain without histology
43.6
14.2
17
*
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
6.9
14.1
22
33
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
18.1
13.9
21
12
WX872
NOMESCO Finland
Intensive care
3.8
13.8
44
124
Q03.9
ICD-10 Finland
Congenital hydrocephalus, unspecified
+∞
13.6
13
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.9
13.6
67
248
C71.60
ICD-10 Finland
Malignant tumor of cerebellum without histology
143.2
13.5
14
*
R4120
NOMESCO Finland
Occupational therapy
3.2
13.5
55
182
SPAT1231
SPAT
Assessment of adjustments needed in living environment
6.3
13.5
23
38
SPAT1216
SPAT
Assessment of functional ability
2.4
13.5
110
522
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
14.2
13.3
22
16
N99
ICPC
Neurological disease other
12.6
13.2
23
19
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.0
13.1
38
100
N05BA09
ATC
clobazam; oral
13.4
13.0
22
17
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
51.2
12.9
15
*
G93.0
ICD-10 Finland
Cerebral cysts
24.9
12.5
17
7
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
132.8
12.5
13
*
WX730
NOMESCO Finland
Conventional respirator
10.8
12.3
23
22
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
12.2
72
293
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
10.4
12.1
23
23
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
5.8
12.0
22
39
183
Kela drug reimbursment
Lamotrigin and topiramate
9.9
11.8
23
24
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.8
11.8
27
59
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
12.9
11.7
20
16
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
11.7
138
758
130
Kela drug reimbursment
Malignant tumour
2.7
11.6
64
251
2139
FHL
Other measure in this category
+∞
11.5
11
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
11.4
104
515
GBB00
NOMESCO Finland
Tracheostomy
12.1
11.4
20
17
R4110
NOMESCO Finland
Physiotherapy
1.9
11.4
174
1046
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.7
11.4
64
254
JDB10
NOMESCO Finland
Percutaneous gastrostomy
10.8
11.3
21
20
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
35.8
11.3
14
*
R41.0
ICD-10 Finland
Disorientation, unspecified
4.2
11.3
30
74
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
13.0
11.2
19
15
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.5
11.1
22
24
N03AX18
ATC
lacosamide; systemic
14.2
11.0
18
13
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
5.5
10.9
21
39
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
10.9
77
341
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
10.9
10.8
20
19
101
Kela drug reimbursment
Anterior pituitary hypofunction
10.9
10.8
20
19
R11
ICD-10 Finland
Nausea and vomiting
2.6
10.8
68
285
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
13.2
10.7
18
14
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.8
10.7
56
214
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
61.1
10.7
12
*
WX402
NOMESCO Finland
General anaesthesia
2.1
10.7
126
690
WX882
NOMESCO Finland
High dependency care
3.6
10.6
35
101
A06AD11
ATC
lactulose; oral
2.2
10.6
100
502
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
10.5
230
1542
M03BX01
ATC
baclofen; systemic
5.6
10.5
20
37
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
112.0
10.5
11
*
7423A
ICD-9 Finland
Other congenital anomalies of nervous system, Congenital hydrocephalus
+∞
10.4
10
*
C71.69
ICD-10 Finland
Malignant tumor of the cerebellum other or unspecified histology
+∞
10.4
10
*
G40.10
ICD-10 Finland
Simple partial seizures
16.4
10.4
16
10
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.7
10.2
33
94
F83
ICD-10 Finland
Mixed specific developmental disorders
11.6
10.1
18
16
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
11.6
10.1
18
16
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
14.9
10.0
16
11
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
12.5
9.9
17
14
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
9.9
72
323
E23.00
ICD-10 Finland
Panhypopituitarism
26.5
9.8
13
5
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
26.5
9.8
13
5
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
26.5
9.8
13
5
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
20.4
9.8
14
7
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
5.4
9.7
19
36
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
55.9
9.7
11
*
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
55.9
9.7
11
*
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
8.6
9.6
20
24
G41.9
ICD-10 Finland
Status epilepticus, unspecified
15.4
9.6
15
10
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.2
9.5
38
124
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
17.9
9.4
14
8
34793
ICD-8 Finland
Other disease of brain, Hydrocephalus acquisitus NUD
+∞
9.4
9
*
G91.3
ICD-10 Finland
Post-traumatic hydrocephalus, unspecified
+∞
9.4
9
*
P52.2
ICD-10 Finland
Intraventricular (nontraumatic) haemorrhage, grade 3, and grade 4 of fetus and newborn
+∞
9.4
9
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
+∞
9.4
9
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.8
9.4
21
45
ZXC95
NOMESCO Finland
Use of surgical navigator
9.7
9.3
18
19
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
8.5
9.1
19
23
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.8
9.1
45
167
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
37.3
9.0
11
*
N03AX09
ATC
lamotrigine; oral
3.2
9.0
36
118
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
12.8
8.9
15
12
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
14.3
8.7
14
10
H47.1
ICD-10 Finland
Papilloedema, unspecified
11.8
8.6
15
13
WX892
NOMESCO Finland
Monitored bed care
2.6
8.6
53
220
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
6.6
8.6
21
33
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
20.4
8.5
12
6
P85
ICPC
Mental retardation
20.4
8.5
12
6
Z51.5
ICD-10 Finland
Palliative care
2.6
8.5
51
209
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.4
8.5
21
49
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
4.4
8.5
21
49
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
8.4
72
346
R1250
NOMESCO Finland
Evaluation of functional capability
4.1
8.4
23
58
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
13.0
8.4
14
11
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
13.0
8.4
14
11
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
13.0
8.4
14
11
Z3226
NOMESCO Finland
Physiotherapist
1.9
8.4
120
698
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
8.4
185
1228
AAA50
NOMESCO Finland
Intracranial endoscopy
+∞
8.4
8
*
AAF45
NOMESCO Finland
Fenestration of intracranial cyst
+∞
8.4
8
*
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
+∞
8.4
8
*
74209
ICD-8 Finland
Congenital hydrocephalus, Unspecified
+∞
8.4
8
*
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
+∞
8.4
8
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
9.6
8.3
16
17
XX4AW, ,
NOMESCO Finland
14.7
8.2
13
9
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
14.7
8.2
13
9
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
4.4
8.0
20
47
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.0
7.8
34
117
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
11.0
7.8
14
13
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
7.6
82
431
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.5
7.6
26
77
L01AX03
ATC
temozolomide; systemic
12.1
7.6
13
11
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
25.4
7.6
10
*
R32
ICD-10 Finland
Unspecified urinary incontinence
3.9
7.6
22
58
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.3
7.6
58
266
N30.0
ICD-10 Finland
Acute cystitis
2.0
7.5
89
485
WX704
NOMESCO Finland
Intubation
2.5
7.4
49
210
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
81.1
7.4
8
*
R47.0
ICD-10 Finland
Dysphasia and aphasia
8.5
7.4
15
18
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
7.3
24
69
H50.2
ICD-10 Finland
Vertical strabismus
11.0
7.3
13
12
C71.89
ICD-10 Finland
Overall malignant tumor of the brain other or unspecified histology
+∞
7.3
7
*
C71.1
ICD-10 Finland
Malignant neoplasm: Frontal lobe
+∞
7.3
7
*
T85.7
ICD-10 Finland
Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
+∞
7.3
7
*
D33.12
ICD-10 Finland
Cerebellum
+∞
7.3
7
*
AAW99
NOMESCO Finland
Other intracranial operation
+∞
7.3
7
*
G94.2
ICD-10 Finland
Hydrocephalus in other diseases classified elsewhere
+∞
7.3
7
*
3431A
ICD-9 Finland
Infantile cerebral palsy, Hemiplegic
+∞
7.3
7
*
74200
ICD-8 Finland
Congenital hydrocephalus, Communicans
+∞
7.3
7
*
R27.0
ICD-10 Finland
Ataxia, unspecified
16.0
7.2
11
7
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
16.0
7.2
11
7
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
4.6
7.2
17
38
H02.2
ICD-10 Finland
Lagophthalmos
30.4
7.2
9
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
6.7
7.2
17
26
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
7.2
70
355
G40.89
ICD-10 Finland
Other epilepsy
12.2
7.1
12
10
ZXE00
NOMESCO Finland
One hour or less
1.6
7.1
217
1557
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.4
7.0
25
76
R4130
NOMESCO Finland
Speech therapy
3.5
6.9
23
67
R50.9
ICD-10 Finland
Fever, unspecified
1.9
6.9
97
559
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
6.9
43
180
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
6.8
89
500
G04BD07
ATC
tolterodine; oral
2.6
6.8
38
150
RT150, ,
NOMESCO Finland
11.1
6.8
12
11
H50.1
ICD-10 Finland
Divergent concomitant strabismus
11.1
6.8
12
11
C71.70
ICD-10 Finland
Malignant tumor of the brainstem without histology
40.5
6.8
8
*
RT490, ,
NOMESCO Finland
40.5
6.8
8
*
E22.80
ICD-10 Finland
Central precocious puberty
40.5
6.8
8
*
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
40.5
6.8
8
*
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
16.9
6.8
10
6
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
16.9
6.8
10
6
H50.31
ICD-10 Finland
Intermittent exotropia
7.3
6.7
15
21
SPAT1252
SPAT
Overall medication plan or its review
2.5
6.7
44
188
S06.0
ICD-10 Finland
Concussion
2.0
6.7
73
386
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
12.4
6.6
11
9
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
10.2
6.6
12
12
H01AC01
ATC
somatropin; parenteral
7.0
6.5
15
22
R1260
NOMESCO Finland
Evaluation of communicative skills
3.7
6.5
20
55
H53.0
ICD-10 Finland
Amblyopia ex anopsia
7.5
6.4
14
19
I60.4
ICD-10 Finland
Subarachnoid haemorrhage from basilar artery
70.6
6.4
7
*
D33.7
ICD-10 Finland
Benign neoplasm: Other specified parts of central nervous system
70.6
6.4
7
*
Q04.6
ICD-10 Finland
Congenital cerebral cysts
70.6
6.4
7
*
D33.10
ICD-10 Finland
Benign pilosytic astrocytoma of brain stem
70.6
6.4
7
*
G81.0
ICD-10 Finland
Flaccid hemiplegia
70.6
6.4
7
*
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
70.6
6.4
7
*
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
14.5
6.4
10
7
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
14.5
6.4
10
7
R4150
NOMESCO Finland
Neuropsychological rehabilitation
8.3
6.4
13
16
K91
ICPC
Cerebrovascular disease
6.1
6.3
16
27
ZXD00
NOMESCO Finland
Emergency procedure
3.4
6.3
22
66
C71.10
ICD-10 Finland
Malignant tumor in frontal lobe without histology
18.2
6.3
9
5
Q05.2
ICD-10 Finland
Lumbar spina bifida with hydrocephalus
+∞
6.3
6
*
D33.08
ICD-10 Finland
Another benign tumor of the cerebral ventricle
+∞
6.3
6
*
CBH30
NOMESCO Finland
Tarsorraphy
+∞
6.3
6
*
Q85.01
ICD-10 Finland
Neurofibromatosis, type 2
+∞
6.3
6
*
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
+∞
6.3
6
*
D44.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pineal gland
+∞
6.3
6
*
SPAT1234
SPAT
Support of social functional capacity
2.7
6.2
34
133
N06AA09
ATC
amitriptyline; systemic
2.2
6.2
55
268
N05BA01
ATC
diazepam; systemic, rectal
1.9
6.2
79
440
Z3231
NOMESCO Finland
Registered nurse
1.6
6.2
164
1128
SPAT1167
SPAT
Insertion of urinary catheter
3.4
6.2
22
67
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.4
6.2
22
67
F54
ICD-10 Finland
Psychological and behavioural factors associated with disorders or diseases classified elsewhere
12.7
6.1
10
8
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
10.2
6.1
11
11
TJD20
NOMESCO Finland
Change of gastrostomy tube
10.2
6.1
11
11
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.9
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
134
35
49.46
224.48
2.6
1.1
—
—
—
0
0
143
84
22.26
179.78
2.5
2.0
1041.39
238.37
e6/l
1.82
119
65
143
84
22.26
179.78
2.5
1.9
30.63
6.79
e6/l
1.20
115
63
84
19
51.51
144.01
2.7
1.2
—
—
—
0
0
39
22
18.93
48.50
1.6
1.5
—
—
—
0
0
129
468
3.26
27.89
11.3
9.0
1.57
1.16
mmol/l
0.52
100
381
242
1313
2.44
23.50
2.8
2.1
398.22
256.84
u/l
0.46
229
1238
195
1073
2.23
17.27
2.5
2.4
—
—
—
0
0
200
1119
2.20
16.94
4.6
4.3
89.51
89.40
%
0.02
194
1091
301
2044
1.98
14.50
10.4
6.7
1.19
1.22
mmol/l
6.21
277
1859
299
2048
1.95
13.81
2.9
2.6
—
—
—
0
0
24
21
11.87
13.41
1.6
1.0
—
—
—
0
0
359
2640
1.94
13.15
8.9
5.1
6.70
6.62
mmol/l
0.28
351
2460
313
2246
1.85
11.88
9.8
7.2
1.20
1.22
mmol/l
3.56
279
1913
291
2054
1.83
11.53
13.4
13.7
1.19
1.24
inr
0.32
78
616
15
7
21.94
10.73
1.2
1.0
—
—
—
0
0
20
41
5.02
9.37
1.1
1.0
—
—
—
0
0
124
708
1.96
9.22
4.0
4.4
0.84
0.82
mmol/l
1.20
114
664
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
20
27
7.63
9.00
1.5
1.1
—
—
—
0
0
19
25
7.82
8.70
1.6
1.1
—
—
—
0
0
96
521
2.01
8.19
9.9
6.9
—
—
—
0
0
109
619
1.94
8.17
5.2
6.8
1.00
1.09
mmol/l
2.43
99
574
84
440
2.06
7.89
3.8
2.2
341.21
375.98
nmol/l
1.02
78
410
123
737
1.85
7.80
2.3
1.9
—
—
—
0
0
92
515
1.93
7.15
2.2
1.8
—
—
—
0
0
223
1612
1.62
7.07
4.2
3.3
—
—
—
0
0
253
1889
1.60
7.00
5.3
5.1
34.55
35.93
g/l
3.31
237
1775
91
517
1.90
6.76
2.2
1.9
—
—
—
0
0
19
49
3.97
6.76
1.0
1.1
—
—
—
0
0
27
89
3.13
6.70
1.6
1.5
—
—
—
0
0
6
0
+∞
6.26
1.0
0.0
—
—
—
0
0
70
374
1.99
6.21
2.2
2.4
7.70
7.06
ug/l
0.07
55
329
40
171
2.44
6.12
2.4
1.8
0.20
3.07
ug/l
1.11
32
154
33
131
2.61
5.89
3.4
1.6
4.45
7.68
u/l
2.67
27
101
36
158
2.36
5.23
10.5
3.3
1.46
1.41
mmol/l
0.10
36
152
352
2944
1.50
5.20
6.7
4.5
3031.33
2669.89
e6/l
—
9
54
138
949
1.60
5.13
3.2
2.6
6.05
5.69
e6/l
0.09
128
854
199
1487
1.51
5.10
3.6
3.3
2.35
2.36
mmol/l
0.59
167
1315
15
42
3.64
4.79
2.9
3.0
—
—
—
0
0
122
828
1.60
4.76
1.9
1.8
1233.18
1170.84
nmol/l
0.33
97
628
170
1248
1.51
4.67
4.0
3.3
0.40
0.47
e6/l
0.22
139
940
29
122
2.45
4.64
2.4
1.5
—
—
—
0
0
112
759
1.59
4.38
3.1
2.9
1.57
0.93
e6/l
1.44
69
432
19
66
2.94
4.37
1.2
1.7
—
—
—
0
0
19
66
2.94
4.37
1.2
1.7
—
—
—
0
0
30
134
2.31
4.23
2.3
1.5
321.57
291.74
mu/l
0.23
30
125
182
1392
1.45
3.98
4.5
3.3
21.70
111.46
e6/l
1.21
152
1068
30
139
2.22
3.90
1.4
1.2
—
—
—
0
0
75
475
1.66
3.84
5.9
5.2
1.69
1.64
mmol/l
0.03
66
382
7
8
8.84
3.78
1.0
1.4
—
—
—
0
0
11
25
4.46
3.64
1.2
1.0
1.45
1.10
u/l
—
6
17
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
30
144
2.14
3.60
2.6
3.7
0.33
0.34
u/ml
0.09
13
77
114
814
1.50
3.49
3.2
2.9
2.45
2.45
mmol/l
0.06
97
716
211
1689
1.39
3.49
3.8
3.7
33.63
38.26
ng/l
0.26
159
1173
136
1014
1.45
3.34
6.0
3.8
1.01
1.02
kg/l
0.82
18
143
55
333
1.72
3.34
1.8
1.6
—
—
—
0
0
6
7
8.64
3.27
1.2
1.6
—
—
—
0
0
277
2335
1.36
3.26
7.1
6.6
11.89
11.61
umol/l
0.08
260
2201
9
20
4.55
3.12
1.1
1.0
—
—
—
0
0
117
859
1.45
3.11
3.6
3.8
1160.16
336.67
ng/l
0.51
85
671
21
94
2.28
3.00
1.3
1.7
—
—
—
0
0
21
94
2.28
3.00
1.3
1.7
—
—
—
0
0
101
727
1.47
2.97
3.7
3.2
4.65
1.92
e6/l
1.10
60
403
6
10
6.05
2.70
1.0
1.4
—
—
—
0
0
395
4297
0.75
2.65
4.0
4.3
1.39
1.45
mmol/l
2.32
363
3962
10
30
3.37
2.61
1.6
1.8
—
—
—
0
0
372
4076
0.76
2.59
5.9
5.6
39.75
39.75
mmol/mol
0.00
343
3796
8
20
4.04
2.57
1.3
1.2
—
—
—
0
0
8
20
4.04
2.57
1.0
1.1
—
—
—
0
0
8
20
4.04
2.57
1.1
1.2
—
—
—
0
0
5
7
7.19
2.55
1.2
1.4
—
—
—
0
0
25
129
1.98
2.54
1.8
1.7
—
—
—
0
0
120
921
1.38
2.47
1.5
1.7
411.54
6519342.22
pmol/l
0.50
97
767
47
714
0.63
2.45
1.3
1.3
24.82
9.76
u/ml
0.54
19
265
409
4411
0.75
2.43
4.5
4.9
2.67
2.75
mmol/l
1.03
369
4061
6
12
5.04
2.40
1.0
1.0
1732.00
1481.33
miu/ml
—
6
12
42
260
1.66
2.40
1.9
1.7
—
—
—
0
0
5
8
6.29
2.37
1.2
1.4
—
—
—
0
0
21
388
0.52
2.28
1.5
1.7
—
—
—
0
0
7
19
3.72
2.15
1.0
1.3
—
—
—
0
0
51
739
0.66
2.14
1.3
1.3
17.03
34.46
iu/ml
2.84
17
229
42
269
1.61
2.13
1.7
1.4
—
—
—
0
0
24
131
1.87
2.11
1.8
1.7
—
—
—
0
0
14
62
2.29
2.09
1.9
1.7
—
—
—
0
0
11
43
2.59
2.09
2.7
2.6
0.11
0.16
e9/l
0.80
11
34
5
10
5.03
2.07
1.2
6.6
—
—
—
0
0
266
2993
0.79
2.02
3.2
3.1
—
—
—
0
0
386
4156
0.79
1.95
3.7
3.9
1.31
1.29
mmol/l
0.23
355
3822
11
45
2.47
1.94
2.6
2.5
413.45
485.24
e6/l
0.30
11
34
404
4324
0.78
1.92
4.0
4.4
4.50
4.63
mmol/l
1.74
366
4015
131
1061
1.30
1.87
1.5
1.5
20.84
20.61
nmol/l
0.05
117
895
30
185
1.66
1.79
2.2
2.0
—
—
—
0
0
28
171
1.67
1.73
2.3
1.8
—
—
—
0
0
8
30
2.69
1.73
1.3
1.0
—
—
—
0
0
7
24
2.94
1.72
1.7
1.9
467.86
915.67
u/ml
—
7
24
144
1196
1.27
1.69
6.0
3.8
0.00
0.00
estimate
-0.00
37
390
49
344
1.46
1.68
3.5
2.8
70.35
65.88
ml/min/173m2
0.24
17
142
6
19
3.18
1.66
1.5
1.5
199.67
146.38
ng/l
—
6
14
14
69
2.05
1.66
1.3
1.8
—
—
—
0
0
24
143
1.71
1.63
3.0
4.6
3.17
3.40
g/l
0.30
24
137
247
2186
1.23
1.63
5.3
3.6
0.00
0.00
estimate
0.50
42
431
202
1758
1.23
1.56
2.2
2.0
90.28
94.88
pmol/l
0.66
106
902
208
1816
1.23
1.55
2.5
2.4
72.87
76.14
nmol/l
0.87
186
1625
402
4271
0.81
1.55
4.3
4.4
5.99
5.92
mmol/l
0.37
368
3889
69
893
0.74
1.54
1.7
1.6
—
—
—
0
0
7
27
2.61
1.52
1.1
1.4
—
—
—
0
0
63
820
0.74
1.46
2.9
2.9
0.64
0.78
ug/l
1.08
43
522
9
38
2.39
1.46
1.9
1.2
3.47
3.63
ug/l
—
9
33
7
28
2.52
1.45
1.1
1.1
—
—
—
0
0
495
5128
0.77
1.45
31.5
20.5
131.71
135.59
g/l
6.39
490
5045
16
88
1.84
1.42
1.6
1.6
—
—
—
0
0
15
81
1.87
1.41
1.9
1.5
—
—
—
0
0
10
46
2.19
1.40
3.1
1.4
7.22
26.74
u/l
—
10
36
495
5125
0.77
1.40
31.3
20.3
4.44
4.51
e12/l
2.32
485
4970
30
198
1.54
1.40
13.6
4.6
9.58
8.94
kpa
1.19
30
189
495
5122
0.77
1.36
31.3
20.3
267.14
249.35
e9/l
5.21
486
4983
5
17
2.96
1.36
1.2
1.1
103.80
83.71
%
—
5
17
495
5121
0.77
1.35
31.7
20.5
39.35
40.16
%
2.34
461
4809
25
161
1.58
1.31
2.6
4.3
100.92
90.49
%
2.09
25
155
16
267
0.59
1.29
1.4
1.9
—
—
—
0
0
32
220
1.48
1.26
3.9
3.6
25.08
24.98
mmol/l
0.06
32
215
295
2703
1.19
1.25
11.5
9.3
4.61
4.04
e9/l
2.42
262
2365
246
2220
1.19
1.25
5.3
3.6
0.00
0.01
estimate
0.50
38
388
243
2191
1.19
1.24
6.8
4.9
0.00
0.00
estimate
-0.00
39
399
12
63
1.92
1.23
1.0
1.1
—
—
—
0
0
88
716
1.27
1.23
2.4
2.4
11.55
13.41
umol/l
1.42
79
668
170
1490
1.20
1.19
3.4
3.5
35.78
32.28
u/l
0.19
161
1424
0
36
0.00
1.14
0.0
1.9
—
—
—
0
0
55
425
1.32
1.14
3.2
3.3
—
—
—
0
0
16
97
1.67
1.07
2.2
1.7
—
—
—
0
0
18
113
1.61
1.07
1.4
1.4
—
—
—
0
0
54
421
1.31
1.06
2.2
2.4
31.87
31.13
u/l
0.07
38
348
13
213
0.60
1.01
1.3
1.9
—
—
—
0
0
46
355
1.32
0.98
10.4
4.5
1.47
1.97
mmol/l
0.63
35
251
397
4160
0.86
0.97
17.6
12.9
86.95
81.92
ml/min/173m2
3.56
333
3391
34
252
1.37
0.94
4.0
2.8
0.47
0.24
e6/l
1.04
34
243
75
621
1.24
0.93
2.7
2.5
20.87
23.07
%
0.60
65
537
14
88
1.61
0.85
3.1
2.6
16.55
15.84
%
—
6
45
365
3464
1.14
0.84
4.0
3.8
15.16
14.74
pmol/l
2.17
330
3122
189
1717
1.15
0.83
5.9
3.7
—
—
—
0
0
8
47
1.71
0.81
1.0
1.4
—
—
—
0
0
17
114
1.51
0.80
1.3
1.8
—
—
—
0
0
9
150
0.59
0.79
1.2
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
98
1124
0.85
0.79
2.3
2.9
330.02
7602.74
umol/l
5.01
89
972
78
664
1.20
0.76
2.5
2.4
2.27
2.34
g/l
0.49
70
616
50
610
0.80
0.76
1.3
1.4
—
—
—
0
0
104
1179
0.86
0.73
1.7
1.7
1.34
1.39
mmol/l
0.29
90
987
117
1314
0.86
0.72
3.9
3.8
9.54
9.53
mg/mmol
0.00
76
842
7
39
1.80
0.72
1.1
1.1
1.50
1.56
nmol/l
—
7
34
10
158
0.63
0.71
1.5
1.7
—
304.00
—
0
5
247
2304
1.13
0.71
8.0
6.2
26.30
28.56
%
2.14
232
2178
9
143
0.62
0.70
1.1
1.1
—
12.41
—
0
18
155
1407
1.14
0.69
2.8
2.5
51.17
59.55
u/l
1.39
143
1304
128
1150
1.14
0.66
2.9
2.3
3.37
2.98
mg/l
0.65
111
985
8
128
0.62
0.64
1.6
4.0
—
2.48
—
0
12
41
500
0.81
0.64
1.6
2.2
—
—
—
0
0
45
543
0.81
0.64
4.8
4.3
30.16
31.35
%
0.37
31
366
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
128
1409
0.88
0.60
3.3
3.3
7.26
7.63
mmol/l
0.36
109
1188
129
1414
0.89
0.56
4.4
4.7
1.63
2.42
ug/l
1.78
119
1263
6
37
1.63
0.55
2.3
2.3
—
—
—
0
0
57
492
1.18
0.51
3.6
4.5
213.72
265.40
u/l
1.60
50
459
9
64
1.41
0.51
1.0
1.2
—
—
—
0
0
39
465
0.83
0.51
1.6
2.1
—
—
—
0
0
282
2953
0.91
0.50
3.2
3.3
51.17
46.69
u/l
0.47
262
2757
21
267
0.78
0.49
1.3
1.2
—
—
—
0
0
7
111
0.63
0.48
1.3
1.5
—
—
—
0
0
12
165
0.72
0.47
2.7
1.8
—
—
—
0
0
63
555
1.15
0.45
2.4
3.6
21.09
9.30
umol/l
0.90
50
483
7
50
1.40
0.45
1.4
1.3
0.54
0.48
nmol/l
—
7
43
25
307
0.81
0.45
1.1
1.2
235.91
150.68
iu/ml
—
7
120
9
129
0.69
0.43
1.0
2.2
0.00
0.00
g/l
—
9
117
14
104
1.35
0.43
1.2
1.2
—
—
—
0
0
9
131
0.68
0.43
1.1
1.3
—
—
—
0
0
43
369
1.18
0.43
1.4
3.1
69.66
66.57
g/l
1.86
36
331
5
31
1.62
0.43
1.0
1.5
89.20
76.58
umol/l
—
5
31
105
1144
0.90
0.42
3.9
4.2
22.77
21.77
%
0.26
46
539
470
4606
1.11
0.41
22.6
13.9
26.12
23.92
mg/l
0.74
390
3611
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
8.76
—
0
18
7
103
0.68
0.40
1.9
1.2
—
—
—
0
0
356
3452
1.08
0.39
8.2
7.5
87.53
81.32
u/l
1.19
336
3221
9
71
1.27
0.36
1.8
1.5
—
—
—
0
0
22
265
0.82
0.35
1.0
1.0
—
—
—
0
0
10
73
1.38
0.34
1.8
1.6
—
—
—
0
0
475
4826
0.91
0.34
11.9
10.3
27.68
26.27
u/l
0.78
460
4654
108
1006
1.09
0.32
2.1
2.0
1.14
1.22
mg/l
0.16
83
774
101
1084
0.92
0.31
1.3
1.3
1.19
1.73
u/ml
0.32
23
270
236
2269
1.07
0.31
7.9
6.0
58.30
56.36
%
1.45
222
2145
7
52
1.35
0.31
1.4
1.3
—
—
—
0
0
11
142
0.77
0.31
1.0
1.1
—
—
—
0
0
8
63
1.27
0.28
1.4
1.8
—
—
—
0
0
13
161
0.80
0.27
1.8
1.7
—
—
—
0
0
134
1276
1.07
0.24
2.8
3.3
1053.93
1434.79
ng/l
1.05
115
1085
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
12
98
1.23
0.21
2.1
1.3
—
—
—
0
0
12
98
1.23
0.21
2.1
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
27.53
—
0
13
9
111
0.81
0.20
1.2
1.3
—
—
—
0
0
15
176
0.85
0.20
1.4
2.0
—
—
—
0
0
6
50
1.20
0.19
1.3
1.5
—
—
—
0
0
6
51
1.18
0.19
1.5
1.3
—
—
—
0
0
11
90
1.23
0.19
5.6
3.6
53.91
56.33
%
0.16
11
90
422
4166
1.05
0.17
4.8
4.5
1.90
2.22
mu/l
0.53
392
3796
5
70
0.71
0.16
1.2
1.5
—
—
—
0
0
7
88
0.79
0.14
1.7
1.8
—
—
—
0
0
8
97
0.82
0.14
1.9
1.6
—
—
—
0
0
9
110
0.82
0.13
1.7
1.3
—
—
—
0
0
17
152
1.12
0.12
2.0
1.9
—
—
—
0
0
52
544
0.95
0.10
1.6
1.8
1.49
1.47
%
0.06
44
484
10
87
1.15
0.09
3.5
3.2
4.27
4.25
e9/l
—
10
87
14
155
0.90
0.09
1.3
1.1
—
—
—
0
0
5
61
0.82
0.08
1.2
1.0
—
—
—
0
0
5
64
0.78
0.08
1.2
1.4
—
—
—
0
0
5
64
0.78
0.08
1.2
1.4
—
—
—
0
0
5
65
0.77
0.08
1.2
1.4
—
—
—
0
0
5
65
0.77
0.08
1.2
1.4
—
—
—
0
0
7
68
1.03
0.08
1.0
1.1
—
—
—
0
0
14
153
0.91
0.07
1.3
1.1
—
—
—
0
0
14
153
0.91
0.07
3.9
2.8
—
—
—
0
0
13
142
0.91
0.06
1.2
1.4
—
—
—
0
0
44
455
0.96
0.05
4.3
4.1
6.58
31.06
ug/l
0.80
38
384
335
3370
0.99
0.04
3.8
4.2
14.60
11.83
mm/h
2.11
305
3099
194
1951
0.99
0.02
3.1
2.7
118.99
123.84
ug/l
0.14
177
1801
11
103
1.07
0.02
1.5
1.7
7.18
6.58
iu/l
—
6
32
12
113
1.06
0.02
1.5
1.4
—
—
—
0
0
10
94
1.06
0.01
1.8
1.6
234.70
233.60
pmol/l
—
10
87
10
105
0.95
0.00
1.3
1.6
—
—
—
0
0
5
49
1.02
0.00
2.6
3.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.2
—
53.45
—
0
6
6
62
0.97
-0.00
2.2
1.7
—
—
—
0
0
6
65
0.92
-0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
0.50
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
52.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint G6_HCOBSTR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCOBSTR | 4.198 [3.58, 4.93] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.317 |
During the follow-up period (1.1.1998 — 31.12.2019), 633 out of 1803 females with G6_HCOBSTR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCOBSTR | 4.142 [3.49, 4.92] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 664 out of 1881 males with G6_HCOBSTR died.
Mortality risk
Mortality risk for people of age
years, who have G6_HCOBSTR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.303% | 0.858% |
| 5 | 2.097% | 4.966% |
| 10 | 5.729% | 12.13% |
| 15 | 11.161% | 22.418% |
| 20 | 19.411% | 35.9% |
Relationships between endpoints
↥Index endpoint: G6_HCOBSTR – Obstructive hydrocephalus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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