external ear disease: A disease involving the external ear. [database_cross_reference: MONDO:DesignPattern]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1304 |
4. Check minimum number of eventsNone |
1304 |
5. Include endpointsNone |
1304 |
6. Filter based on genotype QC (FinnGen only) |
1304 |
Control definitions (FinnGen only)
- Control exclude
- H8_EXTERNAL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified disorders of external ear
based on the number of shared cases.
Similar with more cases:
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8281 | 2364 | 5883 |
| Only index persons | 7659 | 2206 | 5453 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.07 | 0.16 |
| Only index persons | 0.17 | 0.08 | 0.21 |
| Median age at first event (years) | |||
| Whole population | 54.74 | 53.01 | 55.43 |
| Only index persons | 55.12 | 53.64 | 55.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1304 | 331 | 973 |
| Unadjusted period prevalence (%) | 0.35 | 0.11 | 0.43 |
| Median age at first event (years) | 59.23 | 57.41 | 59.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1150
- Matched controls
- 11501
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H61.8
ICD-10 Finland
Other specified disorders of external ear
4854.9
323.0
988
15
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
744.6
196.2
188
*
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
2025.7
176.7
167
*
H61.9
ICD-10 Finland
Disorder of external ear, unspecified
161.3
98.9
103
7
3808A
ICD-9 Finland
Disorders of external ear, Other disorders of external ear[EXOSTOSIS MEATUS ACUSTICI EXTERNI]
+∞
87.6
83
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
8.7
80.8
185
247
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
799.4
77.2
75
*
UDC00
NOMESCO Finland
Ear microscopy
6.3
76.8
224
425
4112
FHL
Removal of ear canal tumor (eg exostosis)
697.2
67.7
66
*
DFF00
NOMESCO Finland
Pure tone audiometry
5.1
65.7
230
536
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.1
65.1
294
884
H60.3
ICD-10 Finland
Other infective otitis externa
25.3
61.6
87
37
H61.2
ICD-10 Finland
Impacted cerumen
7.2
55.7
143
223
H60.8
ICD-10 Finland
Other otitis externa
19.0
55.0
85
48
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.9
40.0
300
1266
H29
ICPC
Ear symptom/complaint other
3.2
27.9
162
565
DC1AD
NOMESCO Finland
Temporalbone CT
12.2
26.4
48
41
H60.4
ICD-10 Finland
Cholesteatoma of external ear
95.6
25.7
28
*
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.4
23.8
124
398
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
4.3
23.1
89
221
H60
ICD-10 Finland
Otitis externa
4.8
22.9
79
175
H01
ICPC
Ear pain/earache
3.1
22.4
130
449
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.1
21.9
291
1583
DBW99
NOMESCO Finland
Other operation on external auditory canal
+∞
20.9
20
*
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
11.2
20.8
39
36
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
5.5
20.3
61
116
H13
ICPC
Plugged feeling ear
2.1
20.2
252
1327
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.7
19.8
46
62
H81
ICPC
Excessive ear wax
2.2
19.6
233
1203
S02CA02
ATC
flumetasone and antiinfectives; otic
3.6
19.2
90
266
H71
ICD-10 Finland
Cholesteatoma of middle ear
10.6
18.7
36
35
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
18.4
339
2073
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.7
18.2
82
235
M01AH05
ATC
etoricoxib; oral
1.7
18.1
636
4788
N02BE01
ATC
paracetamol; systemic, rectal
2.0
17.4
964
8331
A98
ICPC
Health maint/preventive medicine
2.6
17.2
1082
9853
H02
ICPC
Hearing complaint
2.3
17.1
174
832
ZXA05
NOMESCO Finland
Left side
1.9
16.9
308
1868
J01DA01
ATC
[U] cefalexin; systemic
1.7
16.7
673
5215
H65.3
ICD-10 Finland
Chronic mucoid otitis media
6.4
16.0
42
68
ZXA00
NOMESCO Finland
Right side
1.8
15.8
329
2079
H70
ICPC
Otitis externa
5.7
15.7
45
82
DAB00
NOMESCO Finland
Excision of lesion of auricle
7.8
15.4
35
46
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
15.4
161
778
J01DB01
ATC
cefalexin; oral
1.8
15.4
907
7760
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
15.3
539
3980
DFF15
NOMESCO Finland
Speech audiometry
3.5
15.3
73
220
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
4.9
14.3
46
96
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
13.7
505
3738
DAX08
NOMESCO Finland
Fitting of hearing aid
3.2
13.6
72
235
S18
ICPC
Laceration/cut
1.6
13.4
495
3657
M01AE01
ATC
ibuprofen; systemic, rectal
1.8
13.4
971
8595
H60.1
ICD-10 Finland
Cellulitis of external ear
11.1
13.0
24
22
H61.0
ICD-10 Finland
Perichondritis of external ear
50.6
12.9
15
*
J01CA04
ATC
amoxicillin; systemic
1.7
12.8
854
7302
DCD00
NOMESCO Finland
Myringoplasty
11.7
12.8
23
20
4111
FHL
Ear canal extension
131.3
12.5
13
*
E0000UV
ATC
NA
1.6
12.4
399
2824
H66.9
ICD-10 Finland
Otitis media, unspecified
3.2
12.3
65
212
R01AD08
ATC
fluticasone; nasal
1.7
12.1
279
1798
WX110
NOMESCO Finland
Local anesthesy
1.6
11.9
724
5983
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
11.8
519
3966
Z97.4
ICD-10 Finland
Presence of external hearing-aid
2.9
11.7
73
266
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
11.6
141
723
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.5
11.6
54
161
H65.0
ICD-10 Finland
Acute serous otitis media
8.7
11.5
24
28
R01AD12
ATC
fluticasone furoate; nasal
1.7
11.4
269
1740
L08
ICPC
Shoulder symptom/complaint
1.8
11.3
217
1318
Z01.2
ICD-10 Finland
Dental examination
1.6
11.2
394
2840
H60.0
ICD-10 Finland
Abscess of external ear
20.2
11.1
16
8
TDA90
NOMESCO Finland
Removal wax from ear
5.5
11.1
32
60
D82
ICPC
Teeth/gum disease
1.6
11.0
332
2300
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
10.9
210
1278
K02.1
ICD-10 Finland
Caries of dentine
1.5
10.8
570
4508
M01AE02
ATC
naproxen; oral, rectal
1.5
10.7
573
4548
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
60.5
10.6
12
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
10.6
399
2916
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
11.3
10.6
19
17
D07AB02
ATC
hydrocortisone butyrate; topical
1.7
10.6
284
1902
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
7.4
10.5
24
33
D01BA02
ATC
terbinafine; oral; topical
1.6
10.4
299
2039
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
3.0
10.2
59
206
SPAT1043
SPAT
Audiometry
2.0
10.2
131
690
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
10.0
196
1197
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.2
10.0
51
164
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
9.9
440
3328
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
4.6
9.9
33
73
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
9.9
211
1321
H04
ICPC
Ear discharge
3.3
9.9
49
154
WX002
NOMESCO Finland
Sedation and analgesia
1.7
9.8
224
1431
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.9
9.8
150
840
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
9.7
419
3143
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.7
9.7
229
1475
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.6
9.7
27
49
H93.1
ICD-10 Finland
Tinnitus
2.4
9.6
81
354
M01AB05
ATC
diclofenac; systemic, rectal
1.5
9.3
698
5871
J01FA10
ATC
azithromycin; systemic
1.5
9.3
526
4171
N02AX02
ATC
tramadol; systemic, rectal
1.5
9.2
467
3619
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
9.0
254
1716
R01AD09
ATC
mometasone; nasal
1.5
9.0
407
3075
L17
ICPC
Foot/toe symptom/complaint
1.6
9.0
252
1701
H65.2
ICD-10 Finland
Chronic serous otitis media
5.5
8.9
25
46
H92.0
ICD-10 Finland
Otalgia
3.0
8.8
48
162
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.3
8.8
79
355
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
8.8
618
5103
J01AA02
ATC
doxycycline; systemic
1.5
8.6
818
7164
G47.3
ICD-10 Finland
Sleep apnoea
1.6
8.5
257
1762
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
8.3
300
2150
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
4.5
8.3
28
64
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
8.2
180
1131
J01MA02
ATC
ciprofloxacin; systemic
1.5
8.1
434
3378
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
11.8
8.1
14
12
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
8.1
554
4523
J02AC01
ATC
fluconazole; systemic
1.5
8.0
288
2055
R06AX27
ATC
desloratadine; oral
1.6
7.9
217
1452
M79.6
ICD-10 Finland
Pain in limb
1.5
7.8
339
2522
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
7.8
222
1495
L57.0
ICD-10 Finland
Actinic keratosis
1.9
7.8
118
656
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
3.9
7.8
30
78
DGW00
NOMESCO Finland
Dilatation of eustachian tube
45.3
7.7
9
*
J05AB01
ATC
aciclovir; systemic
1.6
7.5
193
1265
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
3.2
7.5
38
123
J01FF01
ATC
clindamycin; systemic
1.5
7.5
283
2039
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
7.5
258
1823
A02BC02
ATC
pantoprazole; systemic
1.4
7.4
682
5842
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.0
7.3
95
500
AA1AD
NOMESCO Finland
CT of head and brain
1.5
7.3
260
1846
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
7.3
264
1882
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
9.4
7.3
14
15
M01AC06
ATC
meloxicam; systemic, rectal
1.5
7.2
350
2656
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.9
7.2
108
604
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.2
222
1529
H74.1
ICD-10 Finland
Adhesive middle ear disease
30.2
7.2
9
*
S29
ICPC
Skin symptom/complaint other
1.6
7.1
173
1119
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
7.0
245
1729
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.0
687
5919
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
7.0
364
2797
SPAT1312
SPAT
General health counselling
1.5
7.0
314
2344
D07AC01
ATC
betamethasone; topical
1.4
6.9
346
2637
WX320
NOMESCO Finland
Spinalanesthesy
1.5
6.9
242
1714
M54.5
ICD-10 Finland
Low back pain
1.5
6.9
306
2280
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
6.8
119
699
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
6.7
6.8
16
24
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
6.8
104
583
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.5
6.8
263
1906
SPAT1153
SPAT
Removal of sutures
1.4
6.7
352
2704
H02AB06
ATC
prednisolone; systemic
1.4
6.7
479
3892
M03BX02
ATC
tizanidine; oral
1.4
6.7
595
5023
J34.2
ICD-10 Finland
Deviated nasal septum
2.1
6.7
69
332
R74
ICPC
Upper respiratory infection acute
1.5
6.7
218
1520
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
6.7
156
999
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.6
321
2430
R05
ICD-10 Finland
Cough
1.6
6.6
182
1218
A02BC05
ATC
esomeprazole; systemic
1.4
6.5
396
3127
X58
ICD-10 Finland
Exposure to other specified factors
1.7
6.5
142
892
N03AX16
ATC
pregabalin; oral
1.5
6.5
236
1681
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
6.4
233
1657
R5140
NOMESCO Finland
Monitoring the use of the aid
1.7
6.4
129
792
DBB02
NOMESCO Finland
Excision of a neoplasm from external auditory canal
70.2
6.4
7
*
DBD10
NOMESCO Finland
Reconstruction of external auditory canal
70.2
6.4
7
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.4
337
2587
R06AX13
ATC
loratadine; oral
1.7
6.4
125
760
M02AA07
ATC
piroxicam; topical
1.4
6.4
351
2718
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.5
6.3
221
1560
UJF32
NOMESCO Finland
Coloscopy
1.5
6.3
268
1970
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
6.3
287
2142
TDA10
NOMESCO Finland
Needle biopsy of auricle or external auditory canal
11.1
6.3
11
10
M01AX05
ATC
glucosamine; oral
1.6
6.3
186
1263
38798
ICD-8 Finland
Other disease of ear and mastoid process, Alii definiti
+∞
6.3
6
*
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
2.0
6.2
75
387
M25.5
ICD-10 Finland
Pain in joint
1.5
6.1
245
1779
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.1
243
1764
R03AC02
ATC
salbutamol; inhalant
1.4
6.0
487
4022
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
6.0
534
4475
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
263
1363
2.16
25.09
5.0
4.7
32.5
31.8
%
0.39
175
931
747
5816
1.67
17.62
2.7
2.6
—
—
—
0
0
1238
11292
2.90
17.10
12.3
10.9
27.4
27.7
u/l
0.17
1188
10896
1267
11726
3.84
16.66
27.0
23.2
6.8
6.8
e9/l
0.44
1231
11385
1266
11720
3.75
16.45
26.9
23.2
235.3
239.0
e9/l
1.31
1235
11416
1266
11724
3.74
16.36
26.9
23.2
4.5
4.5
e12/l
0.50
1231
11381
1266
11727
3.73
16.29
27.1
23.3
136.8
137.0
g/l
0.23
1246
11547
1189
10757
2.19
14.83
5.5
5.2
2.6
2.6
mmol/l
0.02
1060
9880
1130
10058
1.93
14.49
17.6
14.8
77.9
78.6
ml/min/173m2
0.59
993
8386
1213
11082
2.36
14.44
21.3
18.9
139.8
139.7
mmol/l
0.52
1186
10822
1159
10428
2.00
14.04
5.2
4.8
6.1
6.1
mmol/l
0.02
1028
9485
1122
10005
1.87
13.72
6.7
6.2
40.6
40.5
mmol/mol
0.05
996
9250
925
7832
1.62
13.69
4.2
4.0
12.9
12.6
mm/h
0.22
829
7223
1213
11119
2.30
13.68
21.5
19.0
4.0
4.0
mmol/l
0.34
1182
10848
1169
10580
2.01
13.45
18.5
16.0
25.5
26.9
mg/l
0.66
966
8494
1130
10120
1.87
13.33
4.5
4.2
1.3
1.3
mmol/l
0.18
1012
9231
1164
10527
1.98
13.30
5.0
4.6
4.5
4.5
mmol/l
0.19
1047
9738
972
8368
1.63
13.06
8.8
7.9
77.3
79.8
u/l
1.22
914
7894
1157
10456
1.95
13.05
5.1
4.6
1.4
1.4
mmol/l
1.18
1037
9598
804
6648
1.55
12.63
4.8
5.3
6.8
6.8
mmol/l
0.59
759
6269
385
2720
1.59
12.25
2.3
2.6
—
—
—
0
0
714
5777
1.52
12.22
6.8
6.7
11.7
12.5
umol/l
1.29
668
5498
573
4427
1.53
12.19
4.2
3.9
36.0
67.2
ng/l
1.73
430
3302
1223
11330
2.28
12.05
21.0
18.8
85.3
84.3
umol/l
0.40
1223
11325
1057
9369
1.68
11.85
4.9
4.2
2.2
2.0
mu/l
0.56
915
8485
588
4587
1.51
11.84
2.1
2.0
92.4
92.5
pmol/l
0.01
297
2542
819
6909
1.50
10.85
3.7
3.3
49.1
55.9
u/l
1.84
741
6438
244
1602
1.64
10.28
30.1
26.9
1.5
1.4
inr
0.35
31
225
102
515
2.06
10.10
4.0
4.2
24.8
24.8
mmol/l
0.08
90
489
191
1183
1.72
10.02
2.4
2.2
12.5
13.0
nmol/l
0.32
158
1046
139
790
1.85
9.75
3.7
3.8
1.4
1.8
mmol/l
0.58
105
592
448
3438
1.46
9.13
2.2
2.2
218.7
268.7
u/l
0.58
411
3230
457
3534
1.45
8.90
2.9
3.2
1660.2
1572.3
ng/l
0.15
376
3075
813
6981
1.44
8.87
5.2
4.3
1379.3
1298.1
e6/l
—
6
120
143
844
1.78
8.85
3.8
3.8
5.1
5.1
kpa
0.08
127
784
624
5157
1.40
8.18
4.0
4.4
—
—
—
0
0
655
5465
1.40
8.08
6.9
7.6
1.2
1.2
mmol/l
1.47
541
4628
1043
9459
1.51
8.07
18.0
17.0
40.3
40.1
%
0.37
693
6464
729
6213
1.39
7.82
8.9
9.1
4.3
4.3
e9/l
0.15
632
5439
438
3436
1.41
7.62
2.6
2.6
56.4
57.7
u/l
0.30
395
3194
852
7472
1.40
7.61
4.0
3.5
14.7
14.9
pmol/l
0.91
734
6728
603
5009
1.38
7.41
6.4
6.7
1.2
1.2
mmol/l
1.09
534
4548
442
3520
1.39
6.89
3.5
3.5
2.4
2.3
mmol/l
0.85
352
3079
304
2275
1.44
6.75
1.6
1.7
1.1
1.4
mg/l
0.83
236
1789
203
1418
1.51
6.37
4.9
4.1
231.7
244.3
u/l
1.24
193
1342
725
6346
1.32
5.68
6.1
5.1
3.0
3.1
ug/l
0.09
639
5710
401
3228
1.35
5.62
3.7
3.2
0.4
0.5
e6/l
0.55
315
2483
480
3984
1.32
5.42
2.3
2.2
76.9
76.1
nmol/l
0.27
410
3546
282
2166
1.39
5.27
1.9
1.8
1073.2
1145.6
nmol/l
0.44
189
1678
261
1981
1.40
5.24
1.3
1.2
0.9
1.5
u/ml
1.49
67
540
558
4747
1.31
5.22
4.8
5.4
35.4
35.0
g/l
0.85
498
4438
340
2697
1.35
5.18
1.6
1.6
20.4
19.7
nmol/l
0.40
271
2314
114
734
1.61
5.13
1.8
1.6
—
—
—
0
0
255
1937
1.39
5.08
2.0
1.9
—
—
—
0
0
248
1882
1.39
4.96
1.8
2.2
31.0
30.2
s
0.77
238
1830
145
1007
1.49
4.67
3.0
2.7
66.1
66.4
g/l
0.15
127
936
497
4211
1.29
4.64
3.8
3.3
—
—
—
0
0
381
3121
1.31
4.58
3.1
2.9
4064.4
7270.8
umol/l
0.89
321
2713
106
692
1.58
4.53
1.5
1.5
—
—
—
0
0
52
278
1.91
4.51
1.4
1.6
—
—
—
0
0
439
3687
1.29
4.32
3.5
3.1
0.8
0.8
ug/l
0.14
296
2527
306
2459
1.32
4.17
2.7
2.6
4.0
4.1
e6/l
0.06
268
2162
28
124
2.29
3.98
1.1
1.1
4.7
1.9
u/ml
0.33
14
53
78
490
1.63
3.93
2.0
2.0
—
—
—
0
0
149
1077
1.43
3.92
2.0
2.3
151.3
161.2
ug/g
0.12
110
871
184
1381
1.39
3.91
7.8
7.8
—
—
—
0
0
49
275
1.81
3.71
1.8
1.4
7.9
8.8
u/l
0.17
36
220
414
3510
1.26
3.66
3.1
3.4
34.1
39.4
u/l
0.39
385
3347
72
454
1.62
3.60
1.9
1.8
—
—
—
0
0
435
3722
1.25
3.54
3.5
3.2
8.2
8.1
mmol/l
0.07
348
3113
492
4286
1.24
3.37
2.9
2.8
164.8
164.6
ug/l
0.00
442
3946
58
356
1.66
3.24
2.1
1.7
—
—
—
0
0
435
3780
1.23
2.97
4.4
4.0
8.6
9.5
mg/mmol
0.20
282
2523
232
1884
1.28
2.87
3.8
3.1
1.5
1.2
e6/l
0.24
144
1104
65
427
1.55
2.80
1.9
2.7
3.1
3.1
g/l
0.07
50
347
336
2867
1.23
2.70
2.3
2.2
2.9
3.0
mg/l
0.38
270
2459
6
10
6.02
2.70
1.0
1.0
—
—
—
0
0
60
397
1.54
2.52
2.1
2.8
1.1
1.3
g/l
0.15
50
353
28
152
1.86
2.44
6.2
5.0
357.3
356.4
umol/l
0.01
23
135
241
2005
1.25
2.43
3.2
3.2
2.4
2.4
mmol/l
0.15
208
1765
16
70
2.30
2.41
1.6
1.7
—
—
—
0
0
31
175
1.79
2.39
1.4
1.6
—
—
—
0
0
195
1586
1.27
2.39
1.3
1.3
36.7
39.5
iu/ml
0.09
66
479
141
1100
1.32
2.37
2.3
2.3
0.2
0.2
g/l
0.39
129
1023
131
1013
1.33
2.35
2.4
2.5
29.6
85.3
u/l
0.63
112
874
27
147
1.85
2.34
2.0
2.2
14.8
19.8
mg/l
—
6
33
178
1436
1.28
2.33
2.9
2.5
1.7
1.8
%
0.32
151
1284
55
365
1.53
2.31
1.5
2.6
37.2
37.5
g/l
0.12
48
323
47
302
1.58
2.27
1.2
1.4
—
—
—
0
0
157
1251
1.29
2.27
2.6
2.9
6.6
10.0
umol/l
3.08
132
1122
186
1516
1.26
2.24
1.3
1.2
12.4
12.4
u/ml
0.00
62
579
36
217
1.68
2.24
1.3
1.6
—
—
—
0
0
142
1119
1.30
2.23
2.3
2.5
7.6
7.6
ug/l
0.02
110
1020
66
460
1.46
2.20
1.9
2.6
3.9
3.9
g/l
0.03
50
342
66
460
1.46
2.20
1.9
2.6
—
—
—
0
0
66
460
1.46
2.20
1.9
2.6
7.2
7.3
g/l
0.06
50
353
266
2261
1.22
2.19
4.2
4.0
251.9
812.9
ng/l
0.77
220
1876
24
131
1.85
2.09
1.5
1.6
52.3
63.7
%
0.71
15
89
165
1341
1.26
2.05
1.9
1.8
—
—
—
0
0
15
69
2.19
2.05
1.6
1.7
—
—
—
0
0
152
1224
1.27
2.04
4.4
3.6
—
—
—
0
0
220
1848
1.23
2.04
2.7
2.7
12.5
12.9
umol/l
0.39
198
1717
11
44
2.51
2.01
1.3
1.3
—
—
—
0
0
163
1326
1.26
2.01
1.9
1.8
1.6
1.6
%
0.02
129
1138
119
931
1.31
1.99
2.4
2.2
346.1
367.7
nmol/l
0.60
111
862
58
404
1.46
1.97
1.6
1.8
42.2
39.9
nmol/l
0.29
53
389
32
195
1.66
1.94
1.3
1.5
—
—
—
0
0
228
1939
1.21
1.87
3.5
3.5
0.8
0.8
mmol/l
0.17
209
1832
29
174
1.68
1.87
1.3
1.6
—
—
—
0
0
84
631
1.35
1.87
2.3
1.7
—
—
—
0
0
235
2010
1.21
1.82
3.5
2.9
0.7
0.9
e6/l
1.36
148
1222
32
199
1.62
1.81
4.5
3.0
3.3
4.5
e9/l
4.27
32
199
101
784
1.31
1.81
3.8
4.4
88.1
101.2
ng/l
0.92
85
698
17
87
1.97
1.80
1.6
1.4
18.3
24.2
u/l
0.22
11
69
203
1715
1.22
1.79
2.7
2.7
2.3
2.3
g/l
0.31
182
1597
194
1632
1.22
1.78
2.8
2.7
21.6
23.1
%
0.86
167
1385
33
208
1.60
1.78
4.5
3.3
54.6
58.2
%
0.93
33
208
17
88
1.94
1.75
1.1
1.3
—
—
—
0
0
163
1350
1.24
1.74
1.9
1.8
—
—
—
0
0
556
5118
1.15
1.73
4.2
4.5
22.0
21.5
%
0.26
274
2587
35
226
1.56
1.72
1.0
1.2
—
544.0
—
0
5
16
82
1.96
1.70
1.6
1.6
—
—
—
0
0
12
55
2.19
1.67
1.1
1.1
174.4
82.0
u/l
0.51
12
40
23
136
1.70
1.59
1.5
1.7
—
—
—
0
0
27
167
1.63
1.59
1.6
1.5
2358.0
1609.2
e6/l
0.74
22
116
7
26
2.70
1.58
1.4
1.5
—
—
—
0
0
56
409
1.39
1.52
1.1
1.0
—
—
—
0
0
14
257
0.54
1.51
3.2
3.7
40.8
28.8
mg/l
—
8
163
21
123
1.72
1.51
1.3
1.4
0.6
0.7
nmol/l
0.32
21
115
6
21
2.87
1.50
1.0
1.0
—
—
—
0
0
64
479
1.35
1.50
2.7
3.5
4.4
4.5
pmol/l
0.15
56
425
76
584
1.32
1.50
3.4
4.1
24.2
24.1
mmol/l
0.08
67
527
134
1107
1.23
1.49
4.9
7.7
1.4
1.4
mmol/l
0.08
125
1070
155
1301
1.22
1.48
1.4
1.4
—
—
—
0
0
18
102
1.78
1.45
1.2
1.3
—
—
—
0
0
40
278
1.45
1.44
1.4
1.6
14414.6
19008.1
e6/l
0.32
29
206
72
553
1.32
1.44
2.5
1.9
2.1
2.8
ug/l
0.32
63
502
6
22
2.73
1.43
1.7
1.1
—
—
—
0
0
43
305
1.42
1.39
1.4
1.7
—
—
—
0
0
12
60
2.01
1.38
1.5
1.8
—
—
—
0
0
145
1220
1.21
1.36
3.7
4.4
17.4
27.8
ug/l
0.31
113
1027
16
90
1.79
1.33
1.4
1.6
—
—
—
0
0
29
192
1.52
1.32
3.8
4.2
1.1
1.3
%
0.09
20
155
8
34
2.36
1.29
1.0
1.1
—
—
—
0
0
83
661
1.27
1.29
5.4
10.8
24.2
24.3
mmol/l
0.17
77
628
6
132
0.45
1.28
2.3
2.3
—
—
—
0
0
21
130
1.63
1.27
2.2
2.8
—
—
—
0
0
318
2871
1.14
1.27
1.7
1.6
1.4
1.4
mmol/l
0.04
269
2371
57
433
1.33
1.25
1.9
2.6
10.7
10.6
g/l
0.03
49
376
108
891
1.23
1.24
4.8
3.9
1.2
1.2
mmol/l
1.15
94
790
17
100
1.71
1.23
1.5
1.7
—
—
—
0
0
86
696
1.25
1.19
2.4
1.8
—
—
—
0
0
33
232
1.43
1.16
1.0
1.1
4.7
10.3
u/ml
—
5
19
59
458
1.30
1.14
2.9
2.8
—
—
—
0
0
5
111
0.45
1.13
1.0
1.1
—
—
—
0
0
22
143
1.55
1.12
1.2
1.5
—
—
—
0
0
20
127
1.58
1.11
4.8
4.2
—
—
—
0
0
69
549
1.27
1.11
1.5
1.3
430.8
262.0
u/ml
0.26
63
509
5
21
2.39
1.09
1.0
1.0
—
—
—
0
0
22
144
1.54
1.09
1.2
1.5
—
—
—
0
0
22
144
1.54
1.09
1.2
1.5
—
—
—
0
0
204
2294
0.87
1.08
4.4
3.9
1.0
1.0
kg/l
0.45
23
321
11
59
1.87
1.07
1.1
1.0
—
—
—
0
0
38
279
1.37
1.06
1.6
1.5
—
—
—
0
0
29
203
1.44
1.06
2.4
2.1
1.4
1.7
mmol/l
2.22
29
197
13
75
1.74
1.03
1.3
1.5
18.2
20.8
u/ml
—
5
15
551
5195
1.11
1.02
4.1
3.6
0.0
0.0
estimate
0.50
120
942
34
249
1.38
0.98
1.7
1.6
—
—
—
0
0
15
92
1.64
0.97
4.3
3.1
13.2
13.2
%
0.01
15
92
52
408
1.29
0.96
3.2
3.4
54.2
73.7
mg/l
0.54
40
333
52
408
1.29
0.96
3.3
3.4
35.0
82.9
mg/l
0.85
40
334
59
472
1.26
0.94
1.2
1.9
37.6
38.7
u/l
0.19
52
413
25
175
1.44
0.93
1.3
1.6
—
—
—
0
0
72
592
1.23
0.91
1.7
1.9
1.5
1.5
g/l
0.01
61
513
109
934
1.18
0.90
2.9
2.9
63.3
64.0
ml/min/173m2
0.09
51
376
62
502
1.25
0.90
1.2
1.2
96.3
148.6
iu/ml
1.25
20
190
10
56
1.79
0.88
2.1
1.4
1.7
2.2
u/field
—
10
39
6
30
2.00
0.87
4.7
2.1
131.8
132.5
nmol/l
—
6
24
11
64
1.72
0.86
1.4
2.2
—
—
—
0
0
22
153
1.45
0.86
1.6
1.5
114510.2
84552.0
e6/l
0.13
14
90
38
291
1.32
0.85
1.6
1.7
—
—
—
0
0
12
72
1.67
0.85
1.1
1.2
—
—
—
0
0
12
72
1.67
0.85
1.1
1.2
—
—
—
0
0
6
31
1.94
0.84
1.3
1.7
—
—
—
0
0
542
5145
1.09
0.84
4.2
3.5
0.0
0.0
estimate
0.00
122
978
540
5126
1.09
0.83
5.3
4.7
0.0
0.0
estimate
0.00
123
998
122
1064
1.16
0.83
3.3
2.9
307.8
222.4
ng/l
0.55
112
965
33
249
1.33
0.82
4.3
5.8
2063.7
957.7
iu/ml
—
6
40
16
105
1.53
0.82
1.2
1.2
65.8
57.4
u/l
—
9
72
891
8652
1.09
0.80
21.7
19.3
13.8
13.8
%
0.10
874
8458
23
164
1.41
0.80
1.3
1.3
—
—
—
0
0
29
216
1.35
0.79
1.5
1.8
—
—
—
0
0
6
33
1.82
0.79
1.0
1.2
102.7
108.5
%
—
6
27
6
33
1.82
0.79
1.2
1.1
—
—
—
0
0
9
149
0.60
0.79
1.2
1.4
—
—
—
0
0
11
66
1.67
0.78
1.3
2.0
—
—
—
0
0
11
66
1.67
0.78
1.3
2.0
—
—
—
0
0
11
66
1.67
0.78
1.3
2.0
—
—
—
0
0
11
66
1.67
0.78
1.3
2.0
—
—
—
0
0
18
123
1.47
0.77
4.7
4.4
61.5
55.8
%
0.42
11
83
24
175
1.38
0.75
1.5
1.7
—
—
—
0
0
20
141
1.42
0.74
1.1
1.0
—
—
—
0
0
39
307
1.28
0.74
1.2
1.2
—
—
—
0
0
34
263
1.30
0.73
3.3
2.7
15.4
16.1
%
0.37
19
134
30
228
1.32
0.73
1.7
1.3
—
—
—
0
0
20
142
1.41
0.72
1.1
1.5
—
—
—
0
0
20
142
1.41
0.72
1.1
1.5
—
—
—
0
0
20
143
1.40
0.70
1.1
1.5
—
—
—
0
0
38
301
1.27
0.70
1.3
1.5
347.7
274.4
ug/g
1.79
25
184
39
310
1.27
0.70
3.4
3.0
1.7
1.6
mg/l
0.21
33
282
135
1204
1.14
0.69
4.6
3.9
5.9
5.8
kpa
0.27
128
1166
11
69
1.60
0.68
1.5
1.6
2.8
6.5
u/l
—
5
37
39
311
1.26
0.68
1.4
1.6
—
—
—
0
0
5
93
0.54
0.67
1.2
1.5
—
—
—
0
0
11
70
1.58
0.65
1.1
1.2
—
—
—
0
0
134
1202
1.13
0.64
4.5
3.9
1.6
2.0
mmol/l
0.58
111
944
71
825
0.85
0.63
7.9
7.9
25.4
24.4
mmol/l
1.31
66
770
38
306
1.25
0.63
1.2
1.2
—
—
—
0
0
17
121
1.41
0.62
1.2
1.3
267.6
294.9
pmol/l
0.18
17
96
28
217
1.30
0.62
1.9
1.8
—
—
—
0
0
304
2851
1.09
0.62
4.8
3.9
0.0
0.0
estimate
0.39
116
934
0
20
0.00
0.60
0.0
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
10.8
—
6.0
—
0
21
16
114
1.41
0.59
1.3
1.8
—
—
—
0
0
16
114
1.41
0.59
1.3
1.8
—
—
—
0
0
16
114
1.41
0.59
1.3
1.8
—
—
—
0
0
36
291
1.24
0.58
1.4
2.0
18.0
11.3
mg/l
0.49
31
265
31
247
1.26
0.57
1.4
1.3
—
—
—
0
0
31
247
1.26
0.57
1.4
1.3
—
—
—
0
0
6
36
1.67
0.56
1.8
1.0
1722.8
1403.0
miu/ml
—
6
36
17
124
1.38
0.56
1.1
1.1
—
—
—
0
0
18
239
0.75
0.54
1.5
1.2
3.8
3.9
mmol/l
0.24
18
223
12
82
1.47
0.54
1.2
1.3
—
—
—
0
0
6
38
1.58
0.54
1.2
1.3
—
—
—
0
0
110
989
1.12
0.53
4.1
3.1
4.4
4.5
kpa
0.39
104
954
10
66
1.52
0.52
1.1
1.1
—
—
—
0
0
10
66
1.52
0.52
1.1
1.1
—
—
—
0
0
258
2423
1.08
0.52
1.9
1.7
427.9
23619748.7
pmol/l
1.69
188
2028
53
454
1.17
0.50
1.3
1.3
—
—
—
0
0
9
65
1.39
0.50
1.1
1.4
—
—
—
0
0
9
65
1.39
0.50
1.1
1.4
—
—
—
0
0
13
92
1.42
0.50
1.0
1.0
—
—
—
0
0
34
279
1.22
0.50
1.9
1.8
—
—
—
0
0
6
41
1.47
0.50
1.7
1.3
2.2
3.2
ug/l
—
6
31
25
198
1.27
0.49
1.8
1.5
121.2
132.4
u/ml
—
5
32
10
68
1.47
0.47
1.2
1.4
—
52.5
—
0
8
7
48
1.46
0.47
1.6
2.3
—
—
—
0
0
7
48
1.46
0.47
1.4
2.3
—
—
—
0
0
7
48
1.46
0.47
1.4
2.3
—
—
—
0
0
26
209
1.25
0.46
1.3
1.1
—
—
—
0
0
8
121
0.66
0.45
1.0
1.1
—
—
—
0
0
7
50
1.40
0.45
1.0
1.0
—
—
—
0
0
10
69
1.45
0.44
1.1
1.1
—
—
—
0
0
10
69
1.45
0.44
1.1
1.1
—
—
—
0
0
10
69
1.45
0.44
1.1
1.1
—
—
—
0
0
11
78
1.41
0.43
1.9
1.5
0.9
1.0
g/l
0.31
11
78
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
158
1468
1.09
0.43
5.7
8.3
5.1
5.1
kpa
0.28
147
1402
22
273
0.80
0.42
4.7
2.8
70.4
56.1
u/ml
0.20
22
264
8
56
1.43
0.42
1.1
2.5
1222.9
1269.1
u/ml
—
8
56
158
1469
1.09
0.42
5.7
8.3
12.4
12.0
kpa
0.37
147
1405
30
249
1.21
0.42
1.2
1.6
0.8
0.8
nmol/l
0.22
24
209
0
15
0.00
0.41
0.0
2.9
—
69.9
—
0
15
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
2.2
—
0
8
8
59
1.36
0.41
2.5
3.7
—
—
—
0
0
12
88
1.37
0.40
1.1
1.2
—
—
titre
—
0
0
23
187
1.23
0.39
2.6
2.9
—
2344.4
u/ml
—
0
18
40
345
1.16
0.38
1.2
1.3
—
—
—
0
0
9
68
1.33
0.37
5.2
3.5
—
—
—
0
0
9
68
1.33
0.37
2.8
2.4
—
—
—
0
0
126
1168
1.09
0.37
7.6
7.9
10.9
10.5
mmol/l
0.28
112
1110
8
112
0.71
0.37
1.1
1.4
139.5
227.8
pmol/l
—
8
112
5
37
1.35
0.37
1.2
2.1
19.5
242.5
ug/l
—
5
31
25
207
1.21
0.36
1.6
1.2
241.7
280.9
u/ml
0.29
17
119
28
235
1.20
0.36
1.2
1.1
—
—
—
0
0
14
108
1.30
0.35
1.4
1.1
—
—
—
0
0
26
218
1.20
0.34
1.5
1.2
—
—
—
0
0
18
146
1.24
0.32
1.2
1.5
—
—
—
0
0
29
248
1.17
0.32
1.2
1.4
—
—
—
0
0
27
316
0.85
0.32
1.7
1.7
—
—
—
0
0
7
97
0.72
0.31
1.0
1.0
—
—
—
0
0
17
138
1.23
0.30
2.1
2.2
3161.3
3853.9
u/l
—
8
51
37
326
1.14
0.29
1.1
1.8
—
—
—
0
0
20
238
0.84
0.29
1.8
1.4
289.1
216.4
e6/l
0.10
14
201
20
238
0.84
0.29
1.8
1.3
8.2
40.7
e6/l
0.70
13
193
8
111
0.72
0.28
1.3
1.2
—
—
—
0
0
11
140
0.78
0.28
1.1
1.1
115.8
113.5
%
0.14
11
128
10
76
1.32
0.28
1.3
2.0
—
—
—
0
0
89
828
1.08
0.27
1.6
1.6
—
—
—
0
0
155
1472
1.06
0.26
5.7
8.3
0.9
1.1
mmol/l
0.42
123
1137
13
104
1.25
0.26
1.5
1.4
—
—
—
0
0
26
225
1.16
0.26
1.7
1.4
—
15.2
—
0
6
11
87
1.27
0.24
1.0
1.1
—
63.8
—
0
8
29
255
1.14
0.24
2.7
3.0
0.8
0.9
nmol/l
0.65
23
191
409
3990
1.04
0.23
4.3
3.8
—
—
—
0
0
13
107
1.22
0.21
1.6
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
115.3
—
0
10
38
344
1.11
0.21
1.5
2.3
83.0
88.2
%
0.72
38
329
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
49
532
0.92
0.20
6.4
6.4
1.6
1.6
%
0.10
44
497
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
20
174
1.15
0.19
1.1
1.1
—
—
—
0
0
12
99
1.21
0.19
1.4
1.5
38.1
398.0
pmol/l
—
6
28
6
51
1.18
0.19
1.7
3.6
15.6
74.8
u/ml
—
6
51
6
51
1.18
0.19
1.2
1.5
—
—
—
0
0
6
53
1.13
0.18
1.3
1.4
—
—
—
0
0
68
724
0.94
0.18
1.6
1.4
—
—
—
0
0
118
1234
0.95
0.18
6.8
9.0
121.5
122.0
g/l
0.11
112
1188
164
1584
1.04
0.17
6.6
6.6
1.1
1.0
mmol/l
1.33
149
1487
5
70
0.71
0.16
1.0
1.5
—
—
—
0
0
5
70
0.71
0.16
1.0
1.5
—
—
—
0
0
27
244
1.11
0.16
1.1
1.3
—
—
—
0
0
15
130
1.16
0.15
1.4
2.0
—
1616.0
—
0
5
75
788
0.95
0.14
1.6
1.8
—
—
—
0
0
7
86
0.81
0.14
1.3
1.5
—
—
—
0
0
7
86
0.81
0.14
1.3
1.4
—
—
—
0
0
7
86
0.81
0.14
1.3
1.5
—
—
—
0
0
27
246
1.10
0.14
1.2
1.2
17.3
5.8
u/ml
—
5
37
24
222
1.08
0.10
3.0
1.2
38.8
48.9
u/l
0.17
19
192
13
116
1.12
0.09
1.0
1.0
1.9
2.3
u/ml
—
6
43
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
6
56
1.07
0.08
1.2
1.2
86.5
221.9
iu/ml
—
6
56
6
57
1.05
0.08
21.8
18.8
843.0
1403.7
nmol/l
—
6
57
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
479
1.05
0.08
2.5
2.8
0.4
0.3
u/ml
0.86
31
274
5
60
0.83
0.08
1.0
1.1
—
—
—
0
0
27
287
0.94
0.08
1.2
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
7
66
1.06
0.08
1.1
1.2
—
—
—
0
0
7
66
1.06
0.08
1.1
1.6
—
—
—
0
0
12
133
0.90
0.07
1.5
1.9
—
—
—
0
0
33
313
1.06
0.07
1.8
1.6
0.2
21.2
iu/ml
—
8
57
8
78
1.03
0.07
1.9
1.2
1.8
2.0
mmol/l
—
8
73
32
308
1.04
0.04
1.5
2.4
191.8
197.2
%
0.12
32
293
32
332
0.96
0.04
2.0
2.4
55.3
109.8
ug/min
0.81
15
203
14
149
0.94
0.03
1.1
1.2
1.4
5.0
u/ml
—
5
53
14
149
0.94
0.03
1.1
1.2
5.1
6.3
u/ml
—
7
68
10
106
0.94
0.01
1.1
1.1
100.8
95.2
%
—
10
99
10
102
0.98
0.00
1.3
1.2
1.1
1.5
nmol/l
—
10
93
12
121
0.99
0.00
1.4
1.9
—
—
—
0
0
27
269
1.00
0.00
4.9
3.5
7.2
7.6
mmol/l
0.44
27
264
16
163
0.98
0.00
1.3
1.5
—
—
—
0
0
35
347
1.01
0.00
1.1
1.1
—
2.2
—
0
5
26
265
0.98
0.00
2.8
2.3
122.9
129.2
g/l
0.61
21
197
35
355
0.99
0.00
1.3
1.7
3.4
3.0
mg/l
0.10
23
257
10
105
0.95
0.00
1.3
1.4
—
—
—
0
0
14
145
0.97
0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
0.00
1.1
1.0
196.4
298.5
mg/l
—
7
60
0
5
0.00
0.00
0.0
1.0
—
1709.6
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
289.4
—
0
5
0
6
0.00
0.00
0.0
5.0
—
382.8
—
0
6
5
58
0.86
0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
24.2
—
0
8
5
57
0.88
0.00
1.0
1.5
—
—
—
0
0
7
72
0.97
0.00
1.6
1.5
—
—
—
0
0
6
65
0.92
0.00
1.2
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
5
57
0.88
0.00
1.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXTDISNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXTDISNAS | 1.237 [1.0, 1.53] | 0.05 |
| Birth year | 0.992 [0.98, 1.0] | 0.063 |
During the follow-up period (1.1.1998 — 31.12.2019), 211 out of 1882 females with H8_EXTDISNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_EXTDISNAS | 0.863 [0.76, 0.98] | 0.02 |
| Birth year | 0.988 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 652 out of 4632 males with H8_EXTDISNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXTDISNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.1% | 0.141% |
| 5 | 0.707% | 1.015% |
| 10 | 1.709% | 2.44% |
| 15 | 3.23% | 4.766% |
| 20 | 5.448% | 8.588% |
Relationships between endpoints
↥Index endpoint: H8_EXTDISNAS – Other specified disorders of external ear
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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