Other specified disorders of external ear

H8_EXTDISNAS

external ear disease: A disease involving the external ear. [database_cross_reference: MONDO:DesignPattern]

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H61.8, H61.9
  • Hospital discharge: ICD-9 380[8-9]
  • Cause of death: ICD-10 H61.8, H61.9
  • Cause of death: ICD-9 380[8-9]

2 out of 7 registries used, show all original rules.

1386

4. Check minimum number of events

None

1386

5. Include endpoints

None

1386

6. Filter based on genotype QC (FinnGen only)

1341

Control definitions (FinnGen only)

Control exclude
H8_EXTERNAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8281 2364 5883
Only index persons 7659 2206 5453
Unadjusted period prevalence (%)
Whole population 0.14 0.07 0.16
Only index persons 0.17 0.08 0.21
Median age at first event (years)
Whole population 54.74 53.01 55.43
Only index persons 55.12 53.64 55.72

-FinnGen-

Key figures

All Female Male
Number of individuals 1341 357 984
Unadjusted period prevalence (%) 0.36 0.13 0.45
Median age at first event (years) 60.24 58.93 60.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1386
Matched controls
13860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H61.8
ICD-10 Finland
Other specified disorders of external ear
6207.3
307.7
1183
13
H61.9
ICD-10 Finland
Disorder of external ear, unspecified
116.4
286.3
146
14
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
646.1
227.4
219
*
DBB00
NOMESCO Finland
Excision of lesion of external auditory canal
1098.0
199.1
190
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
8.2
165.5
242
347
UDC00
NOMESCO Finland
Ear microscopy
6.7
156.3
285
517
H60.3
ICD-10 Finland
Other infective otitis externa
20.9
145.7
112
58
H60.8
ICD-10 Finland
Other otitis externa
16.9
141.8
121
78
DFF00
NOMESCO Finland
Pure tone audiometry
4.7
113.8
313
807
DC1AD
NOMESCO Finland
Temporalbone CT
24.8
102.5
73
31
3808A
ICD-9 Finland
Disorders of external ear, Other disorders of external ear[EXOSTOSIS MEATUS ACUSTICI EXTERNI]
+∞
100.2
95
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.9
99.5
366
1162
H61.2
ICD-10 Finland
Impacted cerumen
5.7
93.2
191
380
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
147.2
91.3
96
7
4112
FHL
Removal of ear canal tumor (eg exostosis)
801.8
78.1
76
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.7
55.1
377
1670
H60
ICD-10 Finland
Otitis externa
4.8
48.6
114
252
H29
ICPC
Ear symptom/complaint other
3.1
46.0
225
825
H71
ICD-10 Finland
Cholesteatoma of middle ear
11.3
45.3
48
44
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
3.4
41.4
162
518
H70
ICPC
Otitis externa
6.8
38.5
61
93
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.6
38.4
55
75
D23.2
ICD-10 Finland
Benign neoplasm: Skin of ear and external auricular canal
9.1
38.2
47
53
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
3.5
35.6
128
387
H65.3
ICD-10 Finland
Chronic mucoid otitis media
7.7
35.4
50
67
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
5.2
34.4
72
144
H60.4
ICD-10 Finland
Cholesteatoma of external ear
78.2
34.0
38
5
H13
ICPC
Plugged feeling ear
2.2
32.7
349
1836
H01
ICPC
Ear pain/earache
2.8
31.6
169
645
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.2
31.0
350
1878
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.5
30.2
111
340
S02CA02
ATC
flumetasone and antiinfectives; otic
3.3
27.5
107
339
DBW99
NOMESCO Finland
Other operation on external auditory canal
+∞
25.1
24
*
H81
ICPC
Excessive ear wax
2.1
25.0
305
1669
H66.9
ICD-10 Finland
Otitis media, unspecified
3.5
24.9
90
272
Z97.4
ICD-10 Finland
Presence of external hearing-aid
3.1
24.1
108
373
DAB00
NOMESCO Finland
Excision of lesion of auricle
6.4
23.6
39
62
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.2
23.2
218
1076
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
4.7
22.8
53
116
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
22.6
402
2492
H60.1
ICD-10 Finland
Cellulitis of external ear
8.9
22.5
28
32
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.4
22.1
82
252
J01DB01
ATC
cefalexin; oral
2.0
22.0
1141
9663
DAX08
NOMESCO Finland
Fitting of hearing aid
2.8
21.8
116
440
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
5.4
20.2
40
76
TDA90
NOMESCO Finland
Removal wax from ear
5.5
20.0
39
73
H02
ICPC
Hearing complaint
2.0
20.0
235
1261
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
19.3
698
5230
H04
ICPC
Ear discharge
3.5
19.1
68
204
Z01.2
ICD-10 Finland
Dental examination
1.7
18.9
569
4057
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
8.2
18.8
25
31
S18
ICPC
Laceration/cut
1.7
18.8
671
5001
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
5.8
18.6
34
60
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
18.2
589
4268
H65.2
ICD-10 Finland
Chronic serous otitis media
6.0
17.0
30
51
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
5.2
17.0
35
69
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
4.8
16.9
38
81
N02BE01
ATC
paracetamol; systemic, rectal
2.0
16.8
1220
10842
L08
ICPC
Shoulder symptom/complaint
1.8
16.7
311
1930
A98
ICPC
Health maint/preventive medicine
3.0
16.6
1327
12226
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
16.1
260
1543
E0000UV, ,
ATC
1.6
16.0
522
3757
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.1
16.0
66
217
M01AH05
ATC
etoricoxib; oral
1.6
15.7
810
6490
DFF15
NOMESCO Finland
Speech audiometry
2.6
15.6
93
374
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
15.2
929
7723
ZXA00
NOMESCO Finland
Right side
1.7
15.2
383
2578
R01AD08
ATC
fluticasone; nasal
1.7
15.0
352
2323
H61.0
ICD-10 Finland
Perichondritis of external ear
57.3
14.8
17
*
K02.1
ICD-10 Finland
Caries of dentine
1.6
14.8
743
5883
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
14.7
607
4596
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
14.4
541
4000
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
14.4
189
1048
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.7
14.3
358
2400
DCD00
NOMESCO Finland
Myringoplasty
10.6
14.2
27
26
L17
ICPC
Foot/toe symptom/complaint
1.6
14.2
376
2554
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.7
14.2
314
2036
ZXA05
NOMESCO Finland
Left side
1.7
14.2
354
2370
J01CA04
ATC
amoxicillin; systemic
1.7
14.1
1066
9234
R01AD12
ATC
fluticasone furoate; nasal
1.7
14.1
362
2441
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.9
13.7
182
1012
H68.1
ICD-10 Finland
Obstruction of Eustachian tube
5.0
13.6
29
59
D82
ICPC
Teeth/gum disease
1.6
13.6
443
3160
4111
FHL
Ear canal extension
75.9
13.6
15
*
H92.0
ICD-10 Finland
Otalgia
2.7
13.2
72
277
M79.6
ICD-10 Finland
Pain in limb
1.5
13.0
522
3894
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
13.0
65
239
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
12.9
248
1543
SFA20
NOMESCO Finland
Two-surface restoration
1.5
12.8
725
5821
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
12.6
895
7522
J01DA01
ATC
[U] cefalexin
1.5
12.6
791
6477
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
12.6
353
2423
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
12.6
490
3628
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
12.5
667
5277
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
6.3
12.5
21
34
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.5
429
3088
N02AX02
ATC
tramadol; systemic, rectal
1.5
12.4
598
4629
H65.0
ICD-10 Finland
Acute serous otitis media
4.6
12.4
29
64
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
12.2
503
3765
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
12.1
544
4144
H02AB06
ATC
prednisolone; systemic
1.5
12.0
625
4907
M01AE02
ATC
naproxen; oral, rectal
1.5
11.9
698
5607
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.6
11.9
291
1927
SPAT1043
SPAT
Audiometry
1.9
11.8
161
901
M54.5
ICD-10 Finland
Low back pain
1.5
11.7
440
3223
Z71.8
ICD-10 Finland
Other specified counselling
1.6
11.6
363
2548
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
11.5
260
1685
H60.0
ICD-10 Finland
Abscess of external ear
13.7
11.5
19
14
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
11.3
798
6630
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.5
11.0
682
5507
J02AC01
ATC
fluconazole; systemic
1.5
11.0
373
2665
M01AB05
ATC
diclofenac; systemic, rectal
1.5
10.8
860
7279
J01MA02
ATC
ciprofloxacin; systemic
1.5
10.7
535
4135
D01BA02
ATC
terbinafine; oral
1.5
10.6
372
2672
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
10.5
1180
10723
WX002
NOMESCO Finland
Sedation and analgesia
1.6
10.3
270
1814
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.9
10.2
137
763
L57.0
ICD-10 Finland
Actinic keratosis
1.8
10.2
156
906
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
10.2
356
2554
N02BF02
ATC
pregabalin; oral
2.3
10.1
76
340
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.2
10.1
86
406
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
9.9
171
1027
J01FA10
ATC
azithromycin; systemic
1.4
9.9
651
5278
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
9.8
240
1583
J01AA02
ATC
doxycycline; systemic
1.5
9.8
1006
8862
R05
ICD-10 Finland
Cough
1.6
9.7
257
1727
D07AC13
ATC
mometasone; topical
1.5
9.7
361
2620
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
9.7
328
2333
S29
ICPC
Skin symptom/complaint other
1.6
9.5
238
1580
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
9.5
160
956
N03AX16
ATC
[U] pregabalin
1.5
9.4
296
2069
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
12.4
9.4
16
13
A02BC05
ATC
esomeprazole; systemic
1.4
9.3
504
3933
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
9.6
9.3
18
19
A02BC02
ATC
pantoprazole; systemic
1.4
9.3
886
7651
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
9.3
244
1638
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
9.2
514
4028
H93.1
ICD-10 Finland
Tinnitus
2.0
9.2
95
483
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
9.2
485
3763
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.5
9.2
323
2314
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.0
9.1
40
137
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
5.1
9.1
19
38
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.8
9.1
137
791
L03
ICPC
Low back symptom/complaint
1.5
9.0
317
2267
J05AB01
ATC
aciclovir; systemic
1.6
9.0
249
1688
J02AC02
ATC
itraconazole; systemic
1.6
9.0
205
1326
R06AX27
ATC
desloratadine; oral
1.5
9.0
287
2010
SFA10
NOMESCO Finland
One-surface restoration
1.4
9.0
659
5417
G47.3
ICD-10 Finland
Sleep apnoea
1.5
9.0
337
2445
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
9.0
496
3878
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
8.9
374
2774
R01AD09
ATC
mometasone; nasal
1.4
8.9
515
4059
L15
ICPC
Knee symptom/complaint
1.5
8.8
279
1952
J01FF01
ATC
clindamycin; systemic
1.5
8.6
346
2543
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
8.6
217
1441
TDA10
NOMESCO Finland
Needle biopsy of auricle or external auditory canal
9.0
8.5
17
19
UJF32
NOMESCO Finland
Coloscopy
1.5
8.5
347
2557
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
8.4
289
2054
ECA30
NOMESCO Finland
Excision of lesion of gingiva
4.5
8.4
20
45
SPAT1312
SPAT
General health counselling
1.5
8.3
376
2822
DBD10
NOMESCO Finland
Reconstruction of external auditory canal
+∞
8.3
8
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.3
284
2016
ZXE00
NOMESCO Finland
One hour or less
1.4
8.3
479
3762
SDA03
NOMESCO Finland
Periodontal treatment
1.4
8.2
450
3498
M75.2
ICD-10 Finland
Bicipital tendinitis
2.9
8.0
36
125
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
8.0
255
1782
F29
ICPC
Eye symptom/complaint other
1.8
8.0
114
647
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
2.4
8.0
52
219
M03BX02
ATC
tizanidine; oral
1.4
8.0
744
6320
M19.0
ICD-10 Finland
Primary arthrosis of other joints
1.8
8.0
133
792
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
7.9
158
988
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
7.9
341
2535
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
7.9
305
2219
L13
ICPC
Hip symptom/complaint
1.6
7.8
217
1471
SFA30
NOMESCO Finland
Three-surface restoration
1.4
7.8
524
4214
X58
ICD-10 Finland
Exposure to other specified factors
1.6
7.8
185
1209
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.8
7.8
112
638
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.4
7.8
51
216
ZXD20
NOMESCO Finland
Day surgery
1.7
7.7
153
957
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
7.6
388
2971
J01FA09
ATC
clarithromycin; systemic
1.4
7.6
351
2639
L29
ICPC
Musculoskeletal sympt/complt other
1.9
7.6
101
561
WZA90
NOMESCO Finland
Other medical or dental certificate
1.5
7.5
274
1967
S83.2
ICD-10 Finland
Tear of meniscus, current
1.9
7.5
96
526
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.0
7.5
84
440
K08.80
ICD-10 Finland
Toothache NOS
1.9
7.5
91
490
AA1AD
NOMESCO Finland
CT of head and brain
1.4
7.5
371
2824
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
7.5
174
1132
SPAT1153
SPAT
Removal of sutures
1.4
7.4
424
3310
DBB02
NOMESCO Finland
Excision of a neoplasm from external auditory canal
80.5
7.4
8
*
D07AC01
ATC
betamethasone; topical
1.4
7.4
442
3478
Z3229
NOMESCO Finland
Other healthcare associate professional
1.8
7.3
110
635
DBD30
NOMESCO Finland
Correction of atresia of external auditory canal
+∞
7.3
7
*
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.2
7.3
62
294
L14
ICPC
Leg/thigh symptom/complaint
1.8
7.2
100
563
J37.0
ICD-10 Finland
Chronic laryngitis
2.4
7.2
48
205
T78.4
ICD-10 Finland
Allergy, unspecified
2.4
7.2
46
193
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.7
7.1
126
762
R06AX13
ATC
loratadine; oral
1.7
7.1
147
927
R42
ICD-10 Finland
Dizziness and giddiness
1.5
7.1
271
1963
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
7.0
448
3556
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.8
6.9
93
520
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
3.3
6.8
25
77
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.6
6.8
152
978
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
11.0
6.8
12
11
G44.2
ICD-10 Finland
Tension-type headache
1.7
6.8
136
851
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.0
6.7
68
344
DCD10
NOMESCO Finland
Tympanoplasty
16.8
6.7
10
6
J01DA09
ATC
[U] cefadroxil
1.4
6.7
304
2272
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
2.2
6.7
53
244
S82
ICPC
Naevus/mole
1.6
6.7
152
982
R03AC02
ATC
salbutamol; inhalant
1.3
6.7
633
5336
A04
ICPC
Weakness/tiredness general
1.6
6.6
163
1073
R74
ICPC
Upper respiratory infection acute
1.4
6.6
297
2216
R02
ICPC
Shortness of breath/dyspnoea
1.6
6.6
163
1074
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
1.9
6.6
87
483
PD5AD
NOMESCO Finland
CT of aorta
2.5
6.6
39
158
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.7
6.5
114
688
XF402
NOMESCO Finland
ECG with work load test
1.6
6.5
151
981
S06
ICPC
Rash localized
2.0
6.5
71
370
XKD00
NOMESCO Finland
Uroflowmetry
1.4
6.5
289
2153
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
6.2
6.5
16
26
M48.0
ICD-10 Finland
Spinal stenosis
1.6
6.5
165
1096
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.4
232
1661
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
1.8
6.4
89
502
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
6.4
126
785
R06.5
ICD-10 Finland
Mouth breathing
1.7
6.4
127
793
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
2.5
6.4
37
148
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.8
6.4
19
51
R06AE07
ATC
cetirizine; oral
1.4
6.3
453
3655
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
6.3
127
797
38798
ICD-8 Finland
Other disease of ear and mastoid process, Alii definiti
+∞
6.3
6
*
TQW40
NOMESCO Finland
Remowal of suture of skin
1.8
6.2
86
484
WX320
NOMESCO Finland
Spinalanesthesy
1.4
6.2
310
2353
WX290
NOMESCO Finland
Other blockage of nerve
1.3
6.2
517
4259
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
6.2
53
252
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.2
457
3699
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
5.1
6.2
18
36
L28
ICPC
Limited function/disability (L)
1.5
6.2
211
1493
J33.8
ICD-10 Finland
Other polyp of sinus
2.5
6.1
37
151
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.1
431
3461
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
6.1
832
7350
S06.0
ICD-10 Finland
Concussion
1.6
6.1
131
835
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
6.1
294
2220
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
2.3
6.1
42
183
J05AB11
ATC
valaciclovir; oral
1.6
6.1
157
1047
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.4
6.0
268
1993
SPAT1172
SPAT
Guidance concerning hydration
3.0
6.0
26
89

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
285
1445
2.22
28.89
5.0
4.6
32.44
31.80
%
0.40
192
1000
530
3556
1.79
23.05
4.8
4.1
—
—
—
0
0
260
1396
2.06
22.23
1.9
1.7
—
—
—
0
0
1319
12026
3.00
18.57
12.2
10.9
27.38
27.78
u/l
0.34
1267
11608
1348
12486
3.90
17.61
26.8
23.1
6.75
6.84
e9/l
0.71
1309
12122
1348
12491
3.89
17.49
26.9
23.2
136.83
136.92
g/l
0.07
1327
12302
1347
12483
3.81
17.33
26.8
23.1
235.61
239.49
e9/l
1.50
1313
12164
1347
12485
3.80
17.28
26.7
23.0
91.46
91.40
fl
0.20
1325
12300
1347
12486
3.80
17.26
26.6
23.0
30.55
30.50
pg
0.49
1325
12299
1347
12487
3.80
17.23
26.8
23.1
4.51
4.52
e12/l
0.31
1308
12123
1343
12474
3.47
16.17
26.8
23.3
40.68
40.48
%
0.60
1275
11604
1238
11103
2.08
15.95
5.2
4.8
6.06
6.07
mmol/l
0.02
1100
10099
1292
11793
2.41
15.75
21.1
18.8
139.78
139.69
mmol/l
0.65
1263
11520
589
4381
1.60
15.67
2.4
2.1
—
—
—
0
0
1265
11465
2.18
15.40
5.5
5.2
2.64
2.64
mmol/l
0.04
1133
10538
204
1136
1.93
15.36
4.2
4.6
—
—
—
0
0
1197
10651
1.91
15.20
6.7
6.1
40.52
40.47
mmol/mol
0.04
1066
9851
1281
11681
2.28
15.13
17.8
15.0
—
—
—
0
0
1292
11829
2.36
15.00
21.3
18.9
4.01
4.00
mmol/l
0.56
1259
11546
1247
11264
2.07
14.95
18.3
15.9
25.03
26.68
mg/l
0.87
1028
9071
1204
10790
1.88
14.14
4.5
4.2
1.32
1.32
mmol/l
0.01
1081
9845
614
4688
1.56
14.13
4.2
3.8
34.57
65.20
ng/l
1.84
459
3497
985
8372
1.61
14.02
4.3
4.0
12.90
12.61
mm/h
0.21
884
7720
1239
11223
1.98
13.86
5.1
4.6
4.49
4.48
mmol/l
0.10
1118
10393
1232
11145
1.95
13.74
5.2
4.6
1.40
1.38
mmol/l
1.24
1109
10240
631
4868
1.54
13.74
2.1
2.0
92.57
92.59
pmol/l
0.00
319
2708
856
7071
1.55
13.54
4.9
5.3
6.75
6.84
mmol/l
0.68
808
6672
1032
8902
1.62
13.50
8.7
7.9
76.71
79.82
u/l
1.78
969
8411
1134
10024
1.72
13.45
4.9
4.2
2.21
1.98
mu/l
0.52
983
9093
741
5949
1.53
13.23
19.6
17.1
1.35
1.33
inr
0.15
206
1708
501
3712
1.55
12.87
2.2
2.7
—
—
—
0
0
1301
12063
2.28
12.64
20.8
18.7
85.11
84.06
umol/l
0.42
1301
12057
404
2876
1.57
12.29
2.3
2.6
—
—
—
0
0
752
6142
1.49
11.79
6.7
6.7
11.51
12.39
umol/l
1.44
705
5851
918
7832
1.51
11.45
4.9
4.2
—
—
—
0
0
672
5388
1.48
11.41
5.6
5.9
58.05
57.84
%
0.17
619
5080
679
5468
1.47
11.20
6.1
6.1
26.67
26.78
%
0.09
625
5150
667
5360
1.47
11.08
6.2
6.3
8.79
8.92
%
0.41
610
5035
203
1248
1.73
10.91
2.5
2.2
12.65
12.96
nmol/l
0.19
169
1112
482
3648
1.49
10.75
2.2
2.2
211.60
265.35
u/l
0.71
443
3432
666
5372
1.46
10.73
6.8
6.3
—
—
—
0
0
867
7360
1.48
10.69
3.6
3.3
48.76
55.94
u/l
2.12
784
6858
662
5339
1.46
10.64
5.9
6.0
2.98
2.90
%
0.38
609
5011
873
7434
1.47
10.49
5.1
4.3
1193.43
1442.89
e6/l
—
7
133
489
3730
1.48
10.41
2.9
3.2
1610.18
1540.55
ng/l
0.12
401
3243
269
1804
1.61
10.32
2.0
2.2
—
—
—
0
0
106
540
2.04
10.22
4.0
4.2
24.79
24.86
mmol/l
0.09
94
513
706
5802
1.44
10.05
6.9
7.6
1.21
1.21
mmol/l
1.89
590
4947
639
5188
1.43
9.54
6.0
6.0
0.64
0.66
%
0.38
584
4864
651
5308
1.43
9.47
6.3
6.7
1.21
1.20
mmol/l
1.39
579
4855
918
7988
1.44
9.15
4.0
3.5
14.74
14.86
pmol/l
0.79
792
7194
707
5894
1.41
8.84
6.0
6.0
0.21
0.20
e9/l
0.59
621
5179
335
2437
1.49
8.77
1.6
1.7
1.07
1.38
mg/l
1.21
257
1909
686
5700
1.40
8.69
5.6
5.7
0.61
0.61
e9/l
0.10
592
4915
663
5482
1.40
8.61
2.6
2.8
—
—
—
0
0
148
891
1.74
8.52
3.9
3.8
5.14
5.13
kpa
0.05
134
859
686
5715
1.40
8.47
5.7
5.7
0.04
0.04
e9/l
0.37
595
4936
778
6621
1.40
8.47
8.7
9.1
4.28
4.28
e9/l
0.02
675
5791
146
879
1.74
8.40
3.9
3.8
7.42
7.41
ph
0.41
17
105
210
1396
1.59
8.25
1.5
1.4
—
—
—
0
0
697
5844
1.39
8.17
5.7
5.8
1.87
1.95
e9/l
0.40
621
5168
464
3666
1.40
7.62
2.6
2.6
56.41
58.78
u/l
0.57
421
3412
474
3763
1.39
7.55
3.4
3.5
2.35
2.34
mmol/l
0.80
381
3311
217
1497
1.53
7.20
1.4
1.3
—
—
—
0
0
186
1263
1.55
6.62
1.3
1.3
—
—
—
0
0
109
648
1.74
6.58
3.8
3.9
—
—
—
0
0
21
60
3.54
6.45
3.8
2.6
—
—
—
0
0
26
87
3.03
6.24
2.0
1.4
—
—
—
0
0
85
478
1.83
6.19
1.2
1.3
—
—
—
0
0
517
4267
1.34
6.14
2.3
2.2
77.07
76.22
nmol/l
0.28
439
3796
31
116
2.71
6.11
1.0
1.1
2.51
0.96
u/ml
0.60
16
55
303
2303
1.40
6.04
1.9
1.8
1075.65
1144.63
nmol/l
0.44
204
1783
598
5052
1.32
6.00
4.7
5.3
35.50
35.05
g/l
1.13
536
4722
281
2114
1.41
5.93
1.3
1.2
0.84
1.63
u/ml
2.04
71
580
760
6652
1.32
5.86
6.1
5.1
2.91
3.08
ug/l
0.11
670
5977
31
120
2.62
5.74
1.0
1.1
4.39
7.33
u/ml
0.44
17
63
363
2864
1.36
5.73
1.6
1.6
20.41
19.66
nmol/l
0.40
285
2458
358
2831
1.36
5.55
6.7
6.9
—
—
—
0
0
410
3321
1.33
5.39
3.0
2.9
3824.43
6794.37
umol/l
0.88
343
2910
420
3419
1.33
5.32
3.8
3.2
0.37
0.49
e6/l
0.68
336
2656
34
144
2.40
5.25
2.5
2.4
—
—
—
0
0
81
487
1.70
4.75
2.6
1.8
—
—
—
0
0
462
3869
1.29
4.64
3.6
3.1
0.79
0.76
ug/l
0.18
312
2640
162
1151
1.46
4.63
1.9
2.3
140.66
166.50
ug/g
0.44
123
942
152
1067
1.48
4.62
2.9
2.8
66.08
66.40
g/l
0.20
134
992
449
3748
1.29
4.62
4.0
3.3
37.14
94.87
e6/l
1.77
364
2953
128
871
1.52
4.53
2.3
2.5
—
—
—
0
0
110
724
1.56
4.52
2.4
2.4
18.00
19.05
au/ml
—
8
44
324
2606
1.32
4.36
2.7
2.6
4.08
4.13
e6/l
0.03
296
2349
256
2001
1.34
4.18
1.8
2.1
30.99
30.22
s
0.87
246
1945
393
3275
1.28
4.00
3.8
3.2
—
—
—
0
0
463
3954
1.26
3.81
3.5
3.2
8.12
8.09
mmol/l
0.05
372
3322
140
1005
1.44
3.81
1.3
1.4
—
—
—
0
0
109
745
1.50
3.81
2.8
3.3
3.68
6.58
e9/l
2.14
70
612
205
1580
1.35
3.67
1.3
1.2
—
—
—
0
0
490
4227
1.25
3.66
4.6
3.8
73.22
127.11
e6/l
0.93
384
3132
97
654
1.52
3.62
1.3
1.3
84.10
62.71
au/ml
—
7
34
51
292
1.78
3.62
1.8
1.4
7.66
9.08
u/l
0.34
38
233
523
4554
1.24
3.57
3.0
2.8
160.25
164.53
ug/l
0.12
471
4184
426
3631
1.25
3.52
4.9
4.6
—
—
—
0
0
361
3023
1.26
3.47
3.9
4.2
85.92
85.79
%
0.03
353
2959
441
3793
1.24
3.33
3.6
3.3
303.82
251.13
mg/l
0.12
290
2584
32
162
2.00
3.31
5.7
5.1
350.64
357.31
umol/l
0.10
25
144
24
109
2.22
3.26
1.0
1.0
4.49
2.14
u/ml
0.31
13
59
215
1701
1.31
3.21
1.3
1.3
36.86
38.74
iu/ml
0.06
73
521
28
138
2.05
3.12
1.1
1.1
4.69
1.89
u/ml
0.33
14
80
240
1937
1.29
3.09
1.6
1.5
2.48
2.71
g/l
1.13
140
1210
125
915
1.40
3.09
4.3
4.3
0.17
0.13
%
0.20
42
311
103
728
1.45
3.08
1.2
1.2
—
—
—
0
0
297
2465
1.26
3.05
3.2
2.9
602.59
564.28
mosm/kgh2o
2.29
260
2118
206
1633
1.31
3.04
1.3
1.2
11.40
12.29
u/ml
0.06
68
626
357
3028
1.24
3.02
2.2
2.2
2.94
3.03
mg/l
0.37
286
2591
460
4009
1.22
3.01
4.3
3.9
13.22
9.26
mg/mmol
0.42
295
2672
431
3734
1.22
2.98
3.0
3.4
33.84
39.71
u/l
0.48
402
3556
90
626
1.47
2.94
2.7
2.7
—
—
—
0
0
6
9
6.69
2.87
1.8
1.0
—
—
—
0
0
130
977
1.36
2.76
4.3
4.2
1.06
0.96
%
0.14
47
369
119
885
1.38
2.70
4.0
4.0
0.49
0.73
%
0.87
39
313
116
862
1.38
2.65
4.1
4.2
0.06
0.10
%
0.21
33
258
242
1996
1.26
2.61
3.9
3.1
1.50
1.24
e6/l
0.22
149
1168
9
25
3.62
2.57
1.4
1.4
—
—
—
0
0
20
94
2.14
2.55
1.5
1.4
17.41
24.28
u/l
0.29
12
76
257
2144
1.24
2.51
3.1
3.2
2.45
2.45
mmol/l
0.20
223
1885
45
279
1.63
2.48
3.6
2.4
—
—
—
0
0
37
219
1.71
2.43
1.4
1.5
—
—
—
0
0
52
337
1.56
2.40
1.5
1.7
—
—
—
0
0
111
834
1.36
2.39
1.6
1.4
—
—
—
0
0
146
1144
1.31
2.37
3.7
2.7
66.90
69.78
e9/l
0.56
107
887
557
5034
1.18
2.32
12.4
10.0
0.00
0.00
e9/l
0.19
464
4125
137
1075
1.30
2.21
2.6
2.5
29.37
82.48
u/l
0.64
117
926
66
460
1.46
2.20
3.1
3.4
0.25
0.26
g/l
0.04
29
207
149
1187
1.29
2.15
2.4
2.5
7.30
7.48
ug/l
0.05
116
1082
81
589
1.40
2.15
2.4
2.0
1.92
2.74
ug/l
0.37
68
536
163
1317
1.27
2.11
2.6
2.8
6.49
9.75
umol/l
3.12
137
1181
62
431
1.46
2.10
1.7
1.8
41.44
40.01
nmol/l
0.18
57
415
280
2401
1.21
2.09
4.3
4.0
241.03
802.13
ng/l
0.83
231
1991
32
191
1.69
2.07
1.3
1.3
—
—
—
0
0
9
31
2.92
2.07
1.4
1.1
—
—
—
0
0
56
383
1.48
2.06
1.5
2.6
36.97
37.53
g/l
0.30
49
344
17
83
2.06
2.01
1.6
1.6
87.94
86.59
umol/l
0.08
17
83
125
984
1.30
1.99
2.4
2.1
347.76
369.11
nmol/l
0.60
116
914
232
1969
1.21
1.93
2.7
2.7
12.55
12.92
umol/l
0.31
210
1840
14
279
0.50
1.89
3.2
3.7
40.75
28.84
mg/l
—
8
176
25
143
1.76
1.89
1.4
1.5
52.27
64.30
%
0.76
15
92
183
1525
1.23
1.82
2.9
2.5
1.73
1.78
%
0.30
155
1367
5
12
4.18
1.82
1.2
1.1
—
—
—
0
0
248
2131
1.20
1.81
3.6
2.9
0.73
0.91
e6/l
0.83
156
1295
79
592
1.35
1.79
1.3
1.3
—
—
—
0
0
21
116
1.82
1.79
1.2
1.3
—
—
nmol/l
—
0
0
207
1752
1.21
1.78
2.8
2.7
21.71
23.09
%
0.77
179
1490
22
124
1.79
1.76
1.3
1.3
—
—
—
0
0
239
2053
1.20
1.76
3.4
3.5
0.82
0.82
mmol/l
0.01
220
1942
15
74
2.04
1.75
1.5
1.3
—
—
—
0
0
168
1394
1.23
1.75
1.4
1.3
454.81
475.47
titre
0.04
27
300
383
3427
1.16
1.73
4.7
4.3
7.40
7.40
ph
0.13
78
660
106
836
1.29
1.70
3.7
4.4
87.23
101.01
ng/l
1.07
90
749
143
1171
1.25
1.68
2.3
2.3
0.20
0.21
g/l
0.33
131
1091
214
1834
1.20
1.62
2.8
2.6
2.31
2.27
g/l
0.39
192
1704
33
215
1.55
1.57
4.4
3.1
3.33
4.46
e9/l
4.60
33
215
68
510
1.35
1.56
2.7
3.5
4.43
4.50
pmol/l
0.17
58
452
34
224
1.53
1.55
4.5
3.4
54.79
57.97
%
0.82
34
224
48
341
1.42
1.52
1.5
1.7
—
—
—
0
0
37
250
1.49
1.51
1.0
1.1
4.70
8.57
u/ml
—
5
23
22
131
1.69
1.50
1.3
1.3
0.61
0.65
nmol/l
0.23
22
123
22
131
1.69
1.50
1.5
1.5
—
—
—
0
0
90
710
1.29
1.47
1.2
1.4
—
—
—
0
0
179
1524
1.20
1.47
1.8
1.7
—
—
—
0
0
134
1115
1.22
1.39
6.4
9.3
—
—
—
0
0
42
299
1.42
1.34
1.6
1.6
13504.55
18609.43
e6/l
0.40
31
217
352
3186
1.14
1.33
3.5
3.1
—
—
—
0
0
22
136
1.63
1.33
1.0
1.2
—
—
—
0
0
866
8275
1.12
1.33
4.3
4.1
—
—
—
0
0
28
184
1.53
1.32
4.3
3.5
—
—
—
0
0
339
3067
1.14
1.29
1.7
1.7
1.38
1.38
mmol/l
0.02
286
2532
1001
9660
1.13
1.26
20.5
18.8
15.79
15.17
%
1.86
986
9490
76
600
1.28
1.26
1.4
1.3
409.81
254.43
u/ml
0.27
70
556
13
70
1.87
1.24
1.7
1.4
1.11
1.09
nmol/l
—
7
52
27
179
1.52
1.24
1.6
1.5
2358.05
1588.13
e6/l
0.78
22
125
34
237
1.45
1.23
1.7
2.0
—
—
—
0
0
75
597
1.27
1.18
2.8
2.4
—
—
—
0
0
20
125
1.61
1.18
1.4
1.2
—
—
—
0
0
49
368
1.34
1.17
12.1
10.9
—
—
—
0
0
88
716
1.24
1.16
3.2
2.7
—
—
—
0
0
41
300
1.38
1.15
4.1
4.0
—
—
—
0
0
19
118
1.62
1.15
2.1
2.2
—
—
—
0
0
29
199
1.47
1.15
3.8
4.1
1.00
1.44
%
0.36
23
183
25
167
1.51
1.12
1.1
1.1
—
—
—
0
0
23
151
1.53
1.12
1.7
1.6
—
—
—
0
0
73
584
1.26
1.12
1.7
1.6
—
—
—
0
0
16
96
1.67
1.10
1.0
1.0
2.84
1.97
u/ml
—
7
47
117
988
1.20
1.09
5.6
3.7
—
—
—
0
0
589
5552
1.11
1.08
4.2
3.5
0.00
0.00
estimate
0.50
123
995
122
1035
1.20
1.08
3.5
3.2
—
—
—
0
0
44
330
1.34
1.08
1.2
1.2
—
—
—
0
0
16
97
1.66
1.07
4.1
3.0
13.14
13.16
%
0.01
16
97
30
211
1.43
1.06
1.8
2.4
—
—
—
0
0
44
331
1.34
1.06
3.3
3.0
1.71
1.62
mg/l
0.20
38
302
149
1290
1.17
1.05
3.7
4.3
17.08
26.90
ug/l
0.30
116
1082
7
33
2.13
1.05
2.0
1.6
—
—
—
0
0
23
154
1.50
1.04
1.7
1.5
—
—
—
0
0
29
204
1.43
1.03
1.4
1.4
—
—
—
0
0
72
582
1.25
1.03
3.9
3.6
—
—
—
0
0
7
34
2.06
1.03
2.0
2.9
—
—
—
0
0
58
458
1.28
1.00
1.9
2.7
10.49
10.63
g/l
0.08
51
417
12
68
1.77
1.00
1.1
1.1
—
—
—
0
0
35
257
1.37
0.99
1.7
1.9
—
—
—
0
0
9
49
1.84
0.98
1.1
1.4
174.67
193.10
mmol/24h
—
9
49
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
111
945
1.19
0.97
4.9
4.0
1.21
1.22
mmol/l
1.35
97
833
35
259
1.36
0.95
1.7
1.9
—
—
—
0
0
39
294
1.34
0.95
5.8
5.1
2.95
2.49
mmol/l
0.33
26
202
9
51
1.77
0.94
1.4
1.7
—
—
—
0
0
9
51
1.77
0.94
1.1
1.2
—
—
—
0
0
47
365
1.30
0.94
3.3
3.2
25.26
24.73
mmol/l
0.50
47
359
35
260
1.36
0.93
1.7
1.9
—
—
—
0
0
578
5477
1.09
0.92
5.3
4.7
0.00
0.00
estimate
-0.00
127
1057
9
52
1.74
0.92
5.1
7.3
—
—
—
0
0
150
1316
1.16
0.92
4.0
3.9
7.36
7.39
ph
—
5
11
30
218
1.38
0.92
2.6
2.0
1.38
1.73
mmol/l
2.90
30
212
6
28
2.15
0.91
1.5
2.1
—
—
—
0
0
55
438
1.27
0.91
3.4
3.5
34.69
84.16
mg/l
0.97
42
356
55
438
1.27
0.91
3.3
3.5
52.87
73.20
mg/l
0.62
42
355
32
428
0.74
0.90
7.5
7.6
1.31
1.36
mmol/l
0.18
27
370
9
152
0.59
0.89
1.4
1.1
—
—
—
0
0
9
153
0.59
0.89
1.4
1.1
—
—
—
0
0
27
194
1.40
0.88
2.5
2.8
—
—
—
0
0
8
42
1.91
0.88
1.1
2.0
—
—
—
0
0
581
5517
1.09
0.88
4.2
3.5
0.00
0.00
estimate
0.50
136
1110
52
414
1.27
0.87
1.1
1.2
—
—
—
0
0
6
30
2.00
0.87
4.7
2.1
131.83
132.46
nmol/l
—
6
24
20
136
1.48
0.86
1.2
1.3
—
—
—
0
0
20
136
1.48
0.86
3.3
4.9
—
—
—
0
0
21
145
1.46
0.85
1.6
1.5
—
—
—
0
0
42
327
1.29
0.84
1.3
1.5
343.21
273.48
ug/g
1.73
28
200
11
65
1.70
0.82
1.1
1.0
—
—
—
0
0
84
710
1.19
0.82
1.3
1.3
—
—
—
0
0
17
113
1.51
0.82
2.0
2.0
—
—
—
0
0
66
545
1.22
0.82
1.2
1.2
89.12
142.95
iu/ml
1.49
23
207
31
232
1.34
0.81
2.1
1.7
—
—
—
0
0
128
1122
1.16
0.81
3.3
2.9
296.42
217.29
ng/l
0.53
117
1020
39
305
1.29
0.77
1.5
2.0
17.12
11.48
mg/l
0.44
34
277
24
174
1.39
0.77
1.1
1.1
—
—
—
0
0
17
115
1.48
0.77
1.5
1.3
—
—
—
0
0
41
323
1.28
0.77
1.1
1.2
55.00
95.00
titre
—
6
28
102
884
1.17
0.76
2.6
2.7
10.47
10.75
g/l
0.17
89
817
10
59
1.70
0.76
2.4
1.3
7.57
8.77
ug/l
—
10
50
10
59
1.70
0.76
2.1
1.3
1.70
2.43
u/field
—
10
42
21
149
1.42
0.75
1.5
1.3
—
—
—
0
0
74
873
0.84
0.75
7.9
7.7
25.12
24.45
mmol/l
0.82
69
825
15
99
1.52
0.75
1.3
1.1
—
—
—
0
0
17
116
1.47
0.74
1.8
1.3
23.82
25.95
%
0.09
11
73
127
1122
1.15
0.74
1.7
1.6
—
—
—
0
0
74
627
1.19
0.72
1.6
1.9
1.53
1.53
g/l
0.00
63
542
330
3083
1.09
0.71
1.4
1.3
—
—
—
0
0
326
3044
1.09
0.71
4.8
3.8
0.03
0.00
estimate
0.39
118
987
7
40
1.75
0.71
4.9
5.8
—
—
—
0
0
7
41
1.71
0.70
1.6
2.5
—
—
—
0
0
23
169
1.37
0.69
2.3
2.6
—
—
—
0
0
13
85
1.53
0.69
1.5
2.0
41.48
36.72
%
0.34
13
85
33
257
1.29
0.69
1.7
1.8
—
—
—
0
0
10
61
1.64
0.68
5.3
19.0
—
—
—
0
0
11
69
1.60
0.68
1.1
1.1
—
—
—
0
0
18
127
1.42
0.68
4.7
4.3
56.92
55.15
%
0.09
12
111
13
86
1.52
0.66
1.0
1.2
—
—
—
0
0
20
145
1.38
0.66
1.4
1.3
—
—
—
0
0
18
128
1.41
0.65
1.2
1.3
270.61
335.76
pmol/l
0.48
18
112
12
78
1.54
0.65
2.6
2.6
—
—
—
0
0
228
2466
0.91
0.65
4.4
3.9
1.02
1.02
kg/l
0.42
28
345
22
163
1.36
0.64
1.6
1.5
114510.21
78864.87
e6/l
0.16
14
97
8
49
1.64
0.62
1.0
1.1
—
7.40
—
0
11
10
63
1.59
0.62
1.6
1.3
128.40
146.82
nmol/l
—
10
63
129
1158
1.13
0.61
1.5
1.5
—
—
—
0
0
8
50
1.60
0.61
1.1
1.2
—
—
—
0
0
141
1273
1.12
0.61
4.8
3.9
5.89
5.85
kpa
0.20
134
1231
21
156
1.35
0.61
2.2
2.2
2810.86
3341.89
u/l
—
9
60
26
200
1.31
0.61
1.8
1.8
—
—
—
0
0
0
22
0.00
0.59
0.0
10.5
—
6.00
—
0
22
27
210
1.29
0.59
1.7
1.5
121.20
130.08
u/ml
—
5
33
81
707
1.15
0.59
2.4
1.8
1.86
1.51
g/l
0.23
70
651
140
1269
1.11
0.57
4.7
3.9
1.61
2.00
mmol/l
0.64
119
1041
35
283
1.24
0.57
3.7
2.6
15.19
16.15
%
0.58
20
143
14
98
1.43
0.56
1.1
1.4
—
—
—
0
0
19
141
1.35
0.56
1.3
1.2
—
—
—
0
0
5
86
0.58
0.56
2.4
1.4
—
—
—
0
0
10
65
1.54
0.55
1.7
1.1
—
—
—
0
0
39
321
1.22
0.55
3.3
3.4
7.98
7.94
kpa
0.07
39
314
116
1044
1.12
0.54
4.1
3.1
4.41
4.53
kpa
0.31
110
1007
19
142
1.34
0.54
1.2
1.1
—
—
—
0
0
15
205
0.73
0.54
1.7
1.3
56.63
64.50
mmol/l
—
8
175
6
38
1.58
0.54
1.0
1.4
—
—
—
0
0
6
39
1.54
0.53
1.3
1.1
—
—
—
0
0
6
39
1.54
0.53
1.8
1.0
1722.83
1450.59
miu/ml
—
6
39
6
40
1.50
0.51
1.0
1.0
—
—
—
0
0
29
233
1.25
0.51
1.7
1.5
—
—
—
0
0
23
291
0.79
0.50
1.3
1.1
—
—
—
0
0
32
261
1.23
0.50
1.2
1.2
14.92
5.43
u/ml
—
6
39
38
316
1.21
0.50
1.4
1.2
—
—
—
0
0
12
84
1.43
0.49
1.9
1.5
0.92
0.98
g/l
0.30
12
84
168
1553
1.09
0.49
5.6
8.4
5.08
5.12
kpa
0.25
157
1482
168
1554
1.09
0.48
5.6
8.3
12.46
12.03
kpa
0.45
157
1485
312
2959
1.07
0.48
3.8
3.3
—
—
—
0
0
122
1113
1.11
0.47
1.5
1.5
—
—
—
0
0
7
48
1.46
0.47
1.0
1.3
—
—
—
0
0
25
200
1.25
0.46
1.6
1.4
—
—
—
0
0
7
50
1.40
0.45
1.7
1.4
—
—
—
0
0
20
253
0.79
0.44
1.5
1.2
3.74
3.89
mmol/l
0.47
20
235
5
31
1.62
0.43
1.4
1.1
—
—
—
0
0
8
56
1.43
0.42
1.8
1.4
—
1.27
—
0
11
5
32
1.56
0.42
1.8
1.2
—
1.40
%
—
0
5
19
149
1.28
0.42
1.1
1.2
—
—
—
0
0
5
33
1.52
0.41
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
135
1248
1.09
0.41
7.8
7.9
10.74
10.48
mmol/l
0.15
121
1188
8
59
1.36
0.41
1.1
2.4
1222.88
1251.17
u/ml
—
8
59
270
2565
1.07
0.40
1.9
1.7
429.79
28026488.02
pmol/l
2.13
199
2148
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.0
—
—
—
0
0
5
34
1.47
0.40
1.4
2.0
—
—
—
0
0
458
4423
1.05
0.39
3.6
3.3
5.72
5.77
ph
0.13
32
280
50
569
0.87
0.39
6.4
6.2
1.60
1.64
%
0.09
45
531
15
115
1.31
0.39
1.3
1.2
—
—
—
0
0
17
133
1.28
0.38
1.2
1.3
32.81
51.41
mu/l
0.46
17
123
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
9
68
1.33
0.37
1.7
1.3
1.50
1.51
g/l
—
9
68
31
262
1.19
0.37
1.2
1.5
0.80
0.84
nmol/l
0.15
25
219
26
216
1.21
0.37
1.5
1.2
234.36
287.05
u/ml
0.45
18
125
78
707
1.11
0.36
1.4
1.5
—
—
—
0
0
49
432
1.14
0.35
1.1
1.1
—
—
—
0
0
5
76
0.66
0.35
1.4
2.2
—
—
—
0
0
5
77
0.65
0.35
1.2
1.4
—
—
—
0
0
5
77
0.65
0.35
1.2
1.4
—
—
—
0
0
5
80
0.62
0.35
1.2
1.5
—
—
—
0
0
924
9382
0.95
0.34
22.4
20.6
333.43
333.16
g/l
0.42
919
9315
33
283
1.17
0.34
2.9
3.0
—
—
—
0
0
18
145
1.24
0.33
3.7
2.4
1.56
1.72
g/24h
—
8
72
6
45
1.33
0.33
3.0
2.9
—
—
—
0
0
15
118
1.27
0.33
2.5
2.4
—
—
—
0
0
37
424
0.87
0.33
4.8
4.2
3.85
3.97
mmol/l
0.96
37
417
165
1556
1.07
0.32
5.7
8.4
0.83
1.13
mmol/l
0.46
132
1220
32
277
1.16
0.30
2.5
1.7
—
—
—
0
0
39
442
0.88
0.30
1.1
1.1
—
165.13
—
0
8
16
196
0.81
0.30
1.3
1.2
—
—
—
0
0
13
102
1.28
0.30
1.8
1.3
4.91
7.66
g/l
—
8
69
13
102
1.28
0.30
1.8
1.3
0.28
0.45
g/l
—
8
69
7
57
1.23
0.29
1.9
1.5
—
—
—
0
0
36
317
1.14
0.28
1.1
1.1
—
—
—
0
0
123
1308
0.93
0.28
6.9
9.0
121.82
122.22
g/l
0.08
117
1270
12
94
1.28
0.28
1.4
1.2
—
—
—
0
0
51
562
0.90
0.26
6.4
6.3
0.83
0.87
%
0.31
46
525
9
73
1.23
0.25
1.1
1.0
203.67
305.97
mg/l
—
9
64
79
849
0.93
0.25
1.4
1.4
—
—
—
0
0
22
254
0.86
0.23
1.8
1.4
253.12
496.31
e6/l
0.29
16
213
22
254
0.86
0.23
1.7
1.3
7.47
39.43
e6/l
0.75
15
204
27
237
1.14
0.23
2.8
1.2
36.20
49.66
u/l
0.26
21
207
5
38
1.32
0.23
1.2
2.1
19.50
235.22
ug/l
—
5
32
5
38
1.32
0.23
1.4
1.1
—
—
—
0
0
26
229
1.14
0.21
1.7
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
268
2598
1.04
0.21
4.1
3.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
8.00
—
0
6
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
30
268
1.12
0.20
2.6
3.0
0.75
0.86
nmol/l
0.60
23
202
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
132
1262
1.05
0.19
1.7
1.6
—
—
—
0
0
14
118
1.19
0.19
1.1
1.2
—
—
—
0
0
7
58
1.21
0.18
19.9
18.8
836.86
1399.88
nmol/l
—
7
58
7
58
1.21
0.18
1.1
1.2
91.43
223.09
iu/ml
—
7
58
7
59
1.19
0.18
2.4
1.9
—
—
—
0
0
22
195
1.13
0.17
3.8
2.3
—
—
—
0
0
53
567
0.93
0.17
1.4
1.5
—
—
—
0
0
16
139
1.15
0.16
1.4
2.1
—
1616.00
—
0
5
8
71
1.13
0.16
4.5
4.1
—
—
—
0
0
11
92
1.20
0.16
1.5
1.2
—
—
—
0
0
8
72
1.11
0.16
1.1
1.4
—
—
—
0
0
12
102
1.18
0.15
1.4
1.4
133.37
256.29
pmol/l
0.69
12
102
9
82
1.10
0.15
2.7
2.4
—
—
—
0
0
36
333
1.08
0.14
4.2
3.7
—
—
—
0
0
12
103
1.17
0.13
1.8
1.3
—
—
—
0
0
40
373
1.07
0.13
1.1
1.1
—
2.20
—
0
5
70
734
0.95
0.13
8.5
11.8
—
—
—
0
0
28
258
1.09
0.12
3.4
3.0
—
—
—
0
0
12
104
1.16
0.12
3.1
2.1
11.39
11.21
%
0.06
12
104
37
346
1.07
0.12
4.2
3.5
—
—
—
0
0
383
3880
0.98
0.10
3.1
3.0
—
—
—
0
0
172
1684
1.02
0.09
6.7
6.7
1.10
1.04
mmol/l
1.44
156
1582
5
63
0.79
0.08
1.0
1.0
—
—
—
0
0
20
215
0.93
0.07
1.3
1.3
—
—
—
0
0
34
323
1.05
0.07
1.1
1.1
—
—
—
0
0
10
112
0.89
0.07
1.8
1.4
—
—
—
0
0
39
373
1.05
0.07
1.2
1.7
—
—
—
0
0
57
551
1.04
0.07
5.9
4.6
—
—
—
0
0
18
167
1.08
0.07
1.6
1.6
0.70
0.85
g/l
0.41
12
128
90
922
0.97
0.06
4.8
5.4
—
—
—
0
0
144
1417
1.02
0.05
6.2
8.7
95.17
95.47
%
0.19
134
1363
27
283
0.95
0.05
4.9
3.5
7.17
7.60
mmol/l
0.46
27
277
10
110
0.91
0.05
4.5
3.8
—
—
—
0
0
10
91
1.10
0.04
2.5
1.5
—
—
—
0
0
14
149
0.94
0.03
2.4
2.4
—
—
—
0
0
36
351
1.03
0.02
1.7
2.3
52.56
106.56
ug/min
0.87
16
216
31
316
0.98
0.00
4.0
4.6
—
—
—
0
0
16
164
0.98
0.00
1.2
1.2
5.14
7.19
u/ml
—
7
78
27
274
0.99
0.00
3.2
2.3
121.59
129.60
g/l
0.85
22
206
11
111
0.99
0.00
1.3
1.2
1.07
1.49
nmol/l
1.63
11
100
17
171
0.99
0.00
2.8
2.7
—
—
—
0
0
13
127
1.02
0.00
1.0
1.0
1.88
2.08
u/ml
—
6
50
8
82
0.98
0.00
1.4
1.2
—
—
—
0
0
8
83
0.96
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
8
83
0.96
-0.00
1.9
1.2
1.81
1.99
mmol/l
—
8
78
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
382.83
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
5.25
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
3.6
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
289.40
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
8.57
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
174.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
15.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
2.04
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
17.37
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
68.00
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
72
0.97
-0.00
2.7
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
1.56
—
0
8

Mortality – FinRegistry

Association

Association between endpoint H8_EXTDISNAS and mortality.

Females

Parameter HR [95% CI] p-value
H8_EXTDISNAS 1.237 [1.0, 1.53] 0.05
Birth year 0.992 [0.98, 1.0] 0.063

During the follow-up period (1.1.1998 — 31.12.2019), 211 out of 1882 females with H8_EXTDISNAS died.

Males

Parameter HR [95% CI] p-value
H8_EXTDISNAS 0.863 [0.76, 0.98] 0.02
Birth year 0.988 [0.98, 1.0] 0.016

During the follow-up period (1.1.1998 — 31.12.2019), 652 out of 4632 males with H8_EXTDISNAS died.

Mortality risk

Mortality risk for people of age

years, who have H8_EXTDISNAS.

N-year risk Females Males
1 0.1% 0.141%
5 0.707% 1.015%
10 1.709% 2.44%
15 3.23% 4.766%
20 5.448% 8.588%

Relationships between endpoints

Index endpoint: H8_EXTDISNAS – Other specified disorders of external ear

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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