Idiopathic urticaria

L12_URTICA_IDIOPAT

urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L50.1
  • Hospital discharge: ICD-9 7081
  • Cause of death: ICD-10 L50.1
  • Cause of death: ICD-9 7081

2 out of 7 registries used, show all original rules.

843

4. Check minimum number of events

None

843

5. Include endpoints

None

843

6. Filter based on genotype QC (FinnGen only)

810

Control definitions (FinnGen only)

Control exclude
L12_URTICARIAERYTHEMA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L50
Name in latin
Urticaria idiopathica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5662 3560 2061
Only index persons 5072 3268 1804
Unadjusted period prevalence (%)
Whole population 0.09 0.10 0.06
Only index persons 0.10 0.12 0.07
Median age at first event (years)
Whole population 30.93 35.13 23.53
Only index persons 33.36 36.62 27.47

-FinnGen-

Key figures

All Female Male
Number of individuals 810 618 192
Unadjusted period prevalence (%) 0.19 0.22 0.09
Median age at first event (years) 43.46 42.15 47.67

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
843
Matched controls
8430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L50.8
ICD-10 Finland
Other urticaria
186.7
312.7
153
10
L50.1
ICD-10 Finland
Idiopathic urticaria
13176.9
307.7
774
9
L50.9
ICD-10 Finland
Urticaria, unspecified
62.4
307.7
292
71
L50.3
ICD-10 Finland
Dermatographic urticaria
82.1
224.7
120
17
L50.0
ICD-10 Finland
Allergic urticaria
30.8
184.0
124
47
C01CA24
ATC
epinephrine; parenteral
9.1
155.2
223
321
R03DC03
ATC
montelukast; oral
6.2
145.6
363
918
H02AB06
ATC
prednisolone; systemic
6.0
129.5
612
2597
R06AX27
ATC
desloratadine; oral
5.4
128.8
520
1939
T78.3
ICD-10 Finland
Angioneurotic oedema
38.3
128.4
80
23
L50
ICD-10 Finland
Urticaria
17.9
127.1
107
68
XQ800
NOMESCO Finland
Prick test
7.0
112.1
199
355
T78.4
ICD-10 Finland
Allergy, unspecified
8.7
104.5
146
199
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.5
87.1
200
450
R06AE09
ATC
levocetirizine; oral
4.5
85.5
276
820
344
Kela drug reimbursment
Omalizumab
893.1
84.0
81
*
R06AE07
ATC
cetirizine; oral
4.1
83.0
581
2940
R03DX05
ATC
omalizumab; parenteral
856.5
80.8
78
*
7081A
ICD-9 Finland
Urticaria, Idiopathic urticaria
+∞
71.9
68
*
R06AX22
ATC
ebastine; oral
3.5
55.1
255
939
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
6.7
48.3
80
129
A92
ICPC
Allergy/allergic reaction NOS
5.7
43.0
85
163
H02AB07
ATC
prednisone; oral
3.6
42.9
170
559
L04AD01
ATC
ciclosporin; systemic
9.5
38.0
46
51
A02BA02
ATC
ranitidine; systemic
2.9
32.5
182
727
S98
ICPC
Urticaria
41.9
32.4
40
10
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.6
30.7
226
1036
ZX112
NOMESCO Finland
Subcutaneous
7.1
28.7
44
65
R03AC02
ATC
salbutamol; inhalant
2.2
24.8
546
3865
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
7.9
23.1
32
42
S88
ICPC
Dermatitis contact/allergic
5.7
22.6
43
79
R06AX13
ATC
loratadine; oral
2.4
22.1
184
880
L50.5
ICD-10 Finland
Cholinergic urticaria
+∞
20.9
20
*
E0000UV, ,
ATC
2.0
20.0
393
2596
XQ802
NOMESCO Finland
Epicutan test
3.9
19.8
60
162
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.3
19.7
188
949
H02AB04
ATC
methylprednisolone; systemic
2.5
19.0
136
604
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.0
18.7
86
304
R02
ICPC
Shortness of breath/dyspnoea
2.5
18.4
124
535
D07AB08
ATC
desonide; topical
2.5
17.6
118
508
R51.80
ICD-10 Finland
Headache
2.1
16.5
183
975
J46
ICD-10 Finland
Status asthmaticus
4.9
16.5
37
79
D07AC01
ATC
betamethasone; topical
1.9
16.5
303
1927
R03AK07
ATC
formoterol and budesonide; inhalant
2.0
16.1
204
1141
J01MA02
ATC
ciprofloxacin; systemic
1.9
16.0
294
1865
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
16.0
179
956
N02AX02
ATC
tramadol; systemic, rectal
1.9
15.9
331
2183
R06.0
ICD-10 Finland
Dyspnoea
2.0
15.9
218
1254
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
15.9
140
680
L50.2
ICD-10 Finland
Urticaria due to cold and heat
34.1
15.8
20
6
S21
ICPC
Skin texture symptom/complaint
2.3
15.7
136
655
J01AA02
ATC
doxycycline; systemic
1.9
15.7
624
5014
J01FF01
ATC
clindamycin; systemic
1.9
15.4
234
1391
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.7
15.1
49
139
R03BA02
ATC
budesonide; inhalant
2.1
14.9
175
950
D02AX
ATC
Other emollients and protectives
3.8
14.4
45
124
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.6
14.3
88
362
Z71.8
ICD-10 Finland
Other specified counselling
1.8
14.0
306
2032
N05BB01
ATC
hydroxyzine; systemic
2.8
13.7
72
273
A02BC02
ATC
pantoprazole; systemic
1.8
13.7
526
4089
3DX05, ,
NOMESCO Finland
+∞
13.6
13
*
R01AD08
ATC
fluticasone; nasal
1.8
13.4
268
1729
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
13.2
318
2164
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
13.1
340
2361
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.3
13.1
49
153
L20.0
ICD-10 Finland
Besnier prurigo
2.3
12.9
106
497
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.6
12.7
74
296
R03BA08
ATC
ciclesonide; inhalant
2.4
12.6
96
436
X49
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
9.8
12.3
24
25
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
12.0
187
1110
Z2221
NOMESCO Finland
Medical doctor
1.8
11.9
246
1592
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
11.9
256
1678
H02AB09
ATC
hydrocortisone; systemic
4.3
11.8
30
71
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
11.7
102
490
R01AD58
ATC
fluticasone, combinations; nasal
1.8
11.7
253
1658
R03BB04
ATC
tiotropium bromide; inhalant
2.6
11.7
69
278
D07AC13
ATC
mometasone; topical
1.8
11.5
237
1532
X57
ICD-10 Finland
Unspecified privation
4.3
11.3
29
69
S29
ICPC
Skin symptom/complaint other
1.9
11.3
166
965
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
11.2
212
1333
J01
ICD-10 Finland
Acute sinusitis
2.6
11.2
65
260
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
11.1
508
4034
R03BA05
ATC
fluticasone; inhalant
1.8
11.0
177
1060
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
8.4
10.9
23
28
C07AB07
ATC
bisoprolol; oral
1.7
10.8
298
2079
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
10.8
117
613
R06AX26
ATC
fexofenadine; oral
2.3
10.7
81
366
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.9
10.6
52
190
D07AA02
ATC
hydrocortisone; topical
1.9
10.6
144
816
A02BC05
ATC
esomeprazole; systemic
1.6
10.4
315
2244
Z3231
NOMESCO Finland
Registered nurse
1.7
10.4
222
1442
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
10.3
164
978
S02
ICPC
Pruritus
3.1
10.2
43
144
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
10.2
163
971
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
10.1
273
1887
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
10.1
247
1665
XQ818
NOMESCO Finland
Conjunctival allergen provocation test
40.6
10.0
12
*
R01AD09
ATC
mometasone; nasal
1.6
10.0
410
3139
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.2
10.0
26
63
R60.0
ICD-10 Finland
Localized oedema
2.2
9.9
87
419
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.4
9.9
70
308
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
9.8
249
1691
J02AC01
ATC
fluconazole; systemic
1.6
9.8
362
2698
L17
ICPC
Foot/toe symptom/complaint
1.7
9.8
235
1574
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
9.7
205
1324
J45
ICD-10 Finland
Asthma
2.1
9.6
98
500
R20.2
ICD-10 Finland
Paraesthesia of skin
2.3
9.6
73
331
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
9.6
348
2580
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.2
9.6
80
378
L29.9
ICD-10 Finland
Pruritus, unspecified
3.5
9.5
32
93
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
9.5
291
2069
J31.0
ICD-10 Finland
Chronic rhinitis
2.2
9.5
84
406
N03AX16
ATC
[U] pregabalin
1.8
9.5
175
1088
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.2
9.5
79
373
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
9.3
104
549
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.8
9.3
21
45
J01FA06
ATC
roxithromycin; oral
1.6
9.2
311
2262
L29.8
ICD-10 Finland
Other pruritus
5.1
9.1
19
38
R03AC03
ATC
terbutaline; inhalant
1.9
9.0
120
674
R60.9
ICD-10 Finland
Oedema, unspecified
2.8
8.9
45
168
N02BE01
ATC
paracetamol; systemic, rectal
1.9
8.8
725
6478
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
8.8
112
619
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.5
8.7
55
229
A04
ICPC
Weakness/tiredness general
1.8
8.6
132
774
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
8.6
61
268
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
4.6
8.6
20
44
R4110
NOMESCO Finland
Physiotherapy
1.7
8.5
207
1384
P01AB01
ATC
metronidazole; oral, rectal
1.6
8.5
339
2551
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
8.4
85
432
A02BC01
ATC
omeprazole; systemic
1.7
8.4
201
1339
70891
ICD-8 Finland
Urticaria, Recidivans, Chronica
+∞
8.3
8
*
R03AC13
ATC
formoterol; inhalant
2.7
8.3
44
168
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.1
8.3
80
400
J01FA10
ATC
azithromycin; systemic
1.5
8.2
528
4389
Z3226
NOMESCO Finland
Physiotherapist
1.8
8.2
146
895
UJF32
NOMESCO Finland
Coloscopy
1.7
8.2
169
1080
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.2
337
2545
J45.1
ICD-10 Finland
Nonallergic asthma
2.3
8.2
62
281
N01
ICPC
Headache
1.8
8.0
143
877
R05
ICPC
Cough
1.6
8.0
214
1462
J01DB01
ATC
cefalexin; oral
1.7
8.0
685
6068
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.7
8.0
43
166
M03BX02
ATC
tizanidine; oral
1.5
8.0
505
4174
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
6.2
7.9
20
33
R96
ICPC
Asthma
2.1
7.8
77
388
J01FA09
ATC
clarithromycin; systemic
1.6
7.8
263
1896
R74
ICPC
Upper respiratory infection acute
1.5
7.7
336
2561
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
7.7
215
1483
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.2
7.6
30
97
X58
ICD-10 Finland
Exposure to other specified factors
1.8
7.6
123
734
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
7.5
276
2026
M79.6
ICD-10 Finland
Pain in limb
1.5
7.5
329
2510
U07
ICPC
Urine symptom/complaint other
2.3
7.5
58
266
EB1AA, ,
SPAT
2.1
7.4
68
334
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
7.3
155
997
XQ810
NOMESCO Finland
Physical test for urticaria
+∞
7.3
7
*
R05
ICD-10 Finland
Cough
1.6
7.1
174
1160
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
7.1
230
1638
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
7.1
43
176
D01
ICPC
Abdominal pain/cramps general
1.8
7.1
117
701
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
7.0
167
1107
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
6.4
7.0
17
27
N06AX16
ATC
venlafaxine; oral
1.7
7.0
133
831
J20
ICD-10 Finland
Acute bronchitis
1.9
6.9
86
471
G44.2
ICD-10 Finland
Tension-type headache
1.7
6.9
130
810
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.0
6.8
79
423
XQ817, ,
NOMESCO Finland
40.4
6.8
8
*
J01MA14
ATC
moxifloxacin; systemic
2.1
6.7
64
319
D11
ICPC
Diarrhoea
1.7
6.7
119
729
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.7
121
745
C07AA05
ATC
propranolol; systemic
1.6
6.6
187
1289
C08CA01
ATC
amlodipine; oral
1.5
6.6
207
1463
AA1AD
NOMESCO Finland
CT of head and brain
1.6
6.6
161
1073
M25.5
ICD-10 Finland
Pain in joint
1.5
6.6
265
1975
R03AK08
ATC
formoterol and beclometasone; inhalant
2.5
6.5
41
171
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
3.1
6.5
26
85
A02BC03
ATC
lansoprazole; oral
1.6
6.5
193
1346
N03AX12
ATC
[U] gabapentin; oral
1.7
6.3
119
741
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
6.3
200
1415
64091
ICD-8 Finland
Medical termination of pregnancy, Weakness (medical-social reason)
2.8
6.3
30
109
R03DA04
ATC
theophylline; systemic, rectal
2.8
6.2
31
115
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
6.2
108
656
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.2
150
995
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
2.4
6.2
43
188
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
6.2
78
430
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.4
6.2
21
62
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
6.1
146
965
L01BB02
ATC
mercaptopurine; oral
4.2
6.1
16
39
R01AD12
ATC
fluticasone furoate; nasal
1.5
6.1
287
2199
U01
ICPC
Dysuria/painful urination
1.9
6.1
74
403
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
8.7
6.1
12
14
E03.89
ICD-10 Finland
Other specified hypothyroidism
2.7
6.0
32
123
A08
ICPC
Swelling
2.5
6.0
36
147
K07
ICPC
Swollen ankles/oedema
2.8
6.0
29
106
M54.5
ICD-10 Finland
Low back pain
1.5
6.0
286
2195

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
165
211
9.48
125.17
1.6
1.5
0.23
0.23
g/l
0.12
157
200
166
220
9.15
122.26
1.6
1.5
1.20
1.17
g/l
0.58
158
207
241
491
6.47
119.39
1.6
1.3
209.17
218.86
u/ml
0.06
235
449
60
15
42.99
99.45
1.1
1.1
1.44
1.41
u/ml
0.00
60
15
603
3587
3.39
57.48
6.7
6.0
0.18
0.18
e9/l
0.17
541
3191
588
3449
3.33
57.35
6.5
5.6
0.55
0.54
e9/l
0.15
521
3036
588
3459
3.31
56.85
6.6
5.6
0.04
0.04
e9/l
1.89
521
3041
561
3244
3.18
55.22
6.1
6.1
—
—
—
0
0
594
3579
3.23
53.79
6.5
5.6
1.98
1.95
e9/l
0.24
533
3221
543
3133
3.06
52.68
6.6
5.7
0.59
0.68
%
3.78
524
2927
550
3269
2.96
49.15
6.6
5.6
2.76
2.76
%
0.00
533
3068
624
3981
3.18
48.84
8.3
8.5
4.17
3.96
e9/l
1.68
560
3496
550
3288
2.94
48.27
6.9
5.9
7.96
8.15
%
0.85
533
3096
557
3408
2.87
45.75
6.9
5.6
28.99
29.34
%
0.38
540
3219
551
3373
2.83
44.84
6.6
5.5
56.60
56.45
%
0.13
531
3181
86
162
5.80
44.39
1.2
1.1
4.22
5.25
u/ml
0.28
70
86
82
156
5.72
41.84
1.1
1.1
0.73
0.71
u/ml
0.02
59
67
89
183
5.32
41.71
1.2
1.2
2.57
4.56
u/ml
0.64
65
99
80
155
5.60
40.00
1.2
1.1
1.38
2.80
u/ml
0.81
63
81
235
992
2.90
38.53
1.5
1.3
565.85
512.93
titre
0.14
41
215
689
5021
3.04
35.57
4.9
3.8
10.36
10.03
mm/h
0.31
664
4665
318
1723
2.36
29.90
6.5
6.2
—
—
—
0
0
131
463
3.17
28.81
1.2
1.2
—
—
—
0
0
30
30
10.33
26.62
1.2
1.1
0.90
1.79
u/ml
0.41
25
15
470
3100
2.17
26.28
7.6
8.4
0.00
0.00
e9/l
0.61
369
2557
66
164
4.28
24.41
1.2
1.9
10.57
10.13
g/l
0.28
59
153
54
116
4.91
23.90
1.1
1.1
4.96
6.86
u/ml
0.25
36
43
38
60
6.59
23.26
1.1
1.1
0.26
3.28
u/ml
0.96
19
20
60
145
4.38
22.99
1.2
2.0
39.55
38.65
g/l
0.45
53
135
152
655
2.61
22.88
1.3
1.2
147.21
149.28
iu/ml
0.02
47
268
33
46
7.43
22.60
1.1
1.1
7.72
0.45
u/ml
0.48
20
12
51
111
4.83
22.22
1.1
1.1
0.07
0.49
u/ml
1.03
33
37
362
2286
2.02
21.35
4.4
3.3
39.54
84.15
e6/l
1.14
261
1518
78
240
3.48
21.29
1.2
1.2
—
—
—
0
0
55
136
4.26
20.45
1.1
1.1
3.44
5.24
u/ml
0.34
38
64
304
1859
1.99
19.16
3.5
2.9
16.05
57.02
e6/l
3.46
246
1395
100
382
2.84
18.89
2.5
2.6
68.14
67.21
g/l
0.69
90
350
270
1606
2.00
18.25
1.5
1.4
2.22
2.17
g/l
0.16
151
1016
102
401
2.76
18.23
1.5
1.4
—
—
—
0
0
279
1681
1.99
18.16
3.2
2.8
—
—
—
0
0
280
1692
1.98
18.05
3.4
2.8
0.32
0.35
e6/l
0.14
228
1245
609
4767
2.00
17.73
4.9
3.9
—
—
—
0
0
32
57
5.80
17.38
1.1
1.2
0.39
4.61
u/ml
0.68
17
24
179
931
2.17
17.23
2.7
2.6
4.04
3.54
e6/l
0.21
103
479
624
4953
2.00
17.08
7.9
6.6
74.13
75.63
u/l
0.31
598
4642
184
979
2.13
16.66
2.7
2.5
1.19
0.96
e6/l
0.23
109
525
85
321
2.83
16.36
1.9
2.2
—
—
—
0
0
685
5667
2.11
16.07
4.9
4.1
14.39
14.46
pmol/l
0.39
660
5226
75
269
2.96
15.84
1.7
1.6
—
—
—
0
0
125
587
2.33
15.29
2.3
2.1
31.63
33.15
u/l
0.20
105
493
760
6601
2.54
15.13
5.9
4.7
1.73
1.98
mu/l
0.76
739
6167
796
7086
3.21
14.86
16.0
11.1
17.85
20.65
mg/l
2.03
675
5441
54
166
3.41
14.73
1.2
1.2
32.48
42.30
u/ml
—
9
16
244
1493
1.89
14.64
2.5
2.4
1746.73
5066.72
umol/l
1.18
224
1322
180
998
2.02
14.40
3.8
3.2
853.49
334.57
ng/l
0.30
105
635
572
4530
1.82
14.27
5.0
4.0
8.43
1025.87
e6/l
—
7
60
56
183
3.21
13.86
1.2
1.2
1.61
2.92
u/ml
—
7
22
74
284
2.76
13.79
1.3
1.2
1.38
1.39
u/ml
—
9
23
56
185
3.17
13.62
1.2
1.2
5.35
11.24
u/ml
0.49
11
34
213
1286
1.88
13.13
3.0
2.4
5.24
8.04
e6/l
2.56
194
1142
266
1722
1.80
13.07
3.6
3.5
7.40
7.40
ph
0.00
26
320
242
1525
1.82
12.99
3.6
3.2
—
—
—
0
0
163
912
1.98
12.57
3.0
3.4
0.81
0.82
mmol/l
0.43
154
858
136
713
2.08
12.56
1.6
1.3
—
—
—
0
0
362
2583
1.70
12.46
4.9
5.5
1.22
1.22
mmol/l
0.49
337
2354
427
3187
1.69
12.40
5.2
5.4
10.56
10.43
umol/l
0.08
406
3001
388
2835
1.68
12.12
2.6
2.3
73.35
74.88
nmol/l
0.51
370
2581
29
66
4.51
11.98
1.2
1.1
—
—
—
0
0
209
1292
1.82
11.80
1.4
1.3
23.42
29.53
iu/ml
0.42
60
421
392
2904
1.65
11.38
5.4
6.1
1.22
1.22
mmol/l
0.22
354
2465
328
2326
1.67
11.26
2.1
1.8
96.22
96.99
pmol/l
0.13
170
1213
377
2776
1.65
11.14
3.2
3.0
5.95
5.88
ph
0.19
43
258
202
1256
1.80
11.11
1.4
1.2
9.72
12.06
u/ml
0.16
71
517
73
310
2.48
11.10
1.1
1.1
—
1.04
—
0
5
342
2463
1.65
10.99
4.9
4.4
36.60
36.49
g/l
0.14
321
2305
721
6320
1.97
10.96
18.4
13.3
19.74
14.33
%
0.49
713
6215
454
3527
1.62
10.63
3.4
2.7
85.76
82.49
ug/l
0.15
432
3310
165
980
1.85
10.48
2.4
2.4
118.89
101.36
ug/g
0.36
132
773
293
2048
1.66
10.46
2.5
2.1
—
—
—
0
0
48
172
2.90
10.17
1.2
1.3
—
—
—
0
0
234
1555
1.70
10.06
2.2
1.7
0.77
0.93
mg/l
0.83
190
1155
45
158
2.95
9.89
2.2
2.9
—
—
—
0
0
268
1857
1.65
9.77
1.4
1.3
3.56
1.79
u/ml
0.52
53
517
246
1673
1.66
9.62
2.6
2.1
160.51
210.81
u/l
0.34
239
1584
116
638
1.95
9.26
1.3
1.2
—
—
—
0
0
162
1005
1.76
8.80
2.3
2.6
2.43
2.43
mmol/l
0.28
141
880
455
3636
1.55
8.73
4.4
4.3
6.41
6.47
mmol/l
0.29
425
3312
36
123
3.01
8.32
1.2
1.3
1.81
6.48
u/ml
1.62
16
54
308
2278
1.55
8.26
3.2
3.0
27.90
29.97
u/l
0.91
298
2170
188
1236
1.67
8.22
2.9
2.7
561.14
542.24
mosm/kgh2o
0.49
161
1056
117
671
1.86
8.21
2.1
1.9
378.71
376.63
nmol/l
0.04
112
621
120
703
1.82
7.86
2.7
2.3
8.13
6.73
umol/l
0.30
103
592
278
2033
1.55
7.74
3.0
3.1
2.34
2.36
mmol/l
0.89
248
1828
91
492
1.95
7.62
3.0
3.5
4.58
4.62
pmol/l
0.13
82
440
82
430
2.00
7.49
1.2
1.2
—
—
—
0
0
795
7407
2.29
7.48
11.5
8.8
25.26
25.43
u/l
0.10
781
7167
142
891
1.71
7.33
2.2
2.2
15.33
13.75
umol/l
1.15
137
824
429
3464
1.49
7.32
3.6
3.2
0.00
0.00
estimate
0.80
61
731
566
4840
1.52
7.24
3.2
2.8
39.57
39.24
u/l
0.04
542
4586
755
6921
1.87
7.23
15.4
11.8
3.90
3.93
mmol/l
2.10
741
6717
753
6900
1.86
7.18
15.2
11.8
139.54
139.59
mmol/l
0.25
740
6709
201
1392
1.58
7.01
4.2
3.9
—
—
—
0
0
121
743
1.73
6.73
2.3
2.2
23.40
23.24
%
0.04
106
647
111
665
1.77
6.73
1.5
1.5
—
—
—
0
0
224
1606
1.54
6.67
2.2
2.0
2.48
2.93
mg/l
3.12
196
1368
425
3472
1.45
6.56
5.3
4.3
0.00
0.00
estimate
0.50
61
704
265
1980
1.49
6.46
2.8
2.6
—
—
—
0
0
348
2752
1.45
6.31
2.3
2.0
—
—
—
0
0
6
0
+∞
6.26
1.0
0.0
0.32
—
u/ml
—
6
0
65
336
2.01
6.20
1.1
1.1
—
—
—
0
0
214
1542
1.52
6.17
2.6
2.1
—
—
—
0
0
427
3517
1.43
6.16
3.6
3.2
0.00
0.00
estimate
0.50
60
682
16
39
4.16
6.11
1.0
1.2
—
—
—
0
0
659
5916
1.52
5.87
4.9
4.7
38.38
38.43
mmol/mol
0.03
629
5563
177
1261
1.51
5.31
2.7
2.9
1032.00
921.74
ng/l
0.17
153
1028
22
75
2.99
5.17
1.1
1.3
—
—
—
0
0
269
2090
1.42
5.13
2.3
2.0
—
—
—
0
0
179
1300
1.48
4.86
1.6
1.4
20.74
21.18
nmol/l
0.15
158
1123
124
835
1.57
4.78
2.5
2.0
—
—
—
0
0
500
4348
1.37
4.67
3.5
3.1
—
—
—
0
0
302
2427
1.38
4.64
12.4
8.7
1.15
1.14
inr
0.07
81
797
267
2106
1.39
4.58
3.6
3.0
45.51
54.52
ng/l
0.10
128
1163
21
75
2.85
4.58
2.9
4.6
87.41
66.98
u/ml
—
7
23
380
3191
1.35
4.33
3.0
2.5
—
—
—
0
0
146
1043
1.48
4.28
1.7
1.5
—
—
—
0
0
17
56
3.08
4.26
1.1
1.0
—
—
—
0
0
787
7490
1.76
4.15
12.5
10.3
—
—
—
0
0
58
333
1.80
4.10
2.6
2.9
170.06
149.15
ng/l
0.14
53
297
21
80
2.67
4.09
2.5
2.9
—
—
—
0
0
826
7997
2.63
4.08
23.5
16.4
266.82
259.88
e9/l
2.49
817
7812
700
6500
1.45
4.01
4.2
3.7
5.72
5.73
mmol/l
0.06
667
6005
11
22
5.05
4.01
1.0
1.0
—
—
—
0
0
32
150
2.18
4.01
1.2
1.0
2.24
2.39
u/ml
0.06
11
75
62
366
1.75
4.00
1.4
1.3
236.90
241.28
miu/ml
0.03
35
183
37
184
2.06
3.99
2.3
2.3
—
—
—
0
0
18
64
2.85
3.97
1.4
1.3
5.70
6.41
g/l
0.71
18
46
18
64
2.85
3.97
1.4
1.3
2.91
2.60
g/l
0.53
18
45
18
64
2.85
3.97
1.4
1.3
0.34
0.36
g/l
0.12
18
46
826
8004
2.59
3.94
23.4
16.4
4.54
4.52
e12/l
0.78
817
7803
21
82
2.60
3.91
1.1
1.3
—
—
nmol/l
—
0
0
42
221
1.95
3.89
1.2
1.2
—
—
—
0
0
826
8007
2.57
3.88
23.5
16.4
6.89
6.68
e9/l
2.34
816
7799
18
65
2.81
3.87
1.3
1.3
—
—
—
0
0
21
83
2.57
3.82
1.2
1.3
—
—
—
0
0
76
482
1.63
3.77
2.4
2.5
4.18
5.83
e9/l
1.10
60
425
45
246
1.88
3.73
1.2
1.1
1.80
6.16
u/ml
—
6
43
824
7993
2.37
3.61
23.4
16.4
40.47
40.18
%
0.91
794
7600
18
68
2.68
3.58
1.1
1.7
—
—
—
0
0
26
118
2.24
3.54
1.2
1.1
—
—
—
0
0
71
452
1.62
3.49
3.0
2.3
—
—
—
0
0
118
846
1.46
3.39
1.3
1.2
—
—
—
0
0
238
1925
1.33
3.32
3.2
2.3
57.62
58.83
u/l
0.13
220
1782
19
78
2.47
3.23
1.8
1.5
—
—
—
0
0
80
535
1.55
3.21
3.7
2.7
1.69
1.76
%
0.19
71
476
9
20
4.54
3.12
1.1
1.4
—
—
—
0
0
25
119
2.13
3.07
1.9
1.7
38082.94
14836.36
e6/l
0.65
18
89
718
6775
1.40
3.06
4.4
4.1
2.82
2.85
mmol/l
0.37
688
6359
32
168
1.94
3.03
1.5
1.4
328.51
312.54
ug/g
0.13
18
97
12
36
3.37
3.02
1.1
1.1
136.36
157.28
iu/ml
0.23
12
36
64
416
1.58
2.92
6.5
7.8
—
—
—
0
0
51
315
1.66
2.86
1.4
1.2
—
—
—
0
0
21
96
2.22
2.85
1.3
1.0
—
—
—
0
0
104
753
1.43
2.85
2.2
1.6
—
—
—
0
0
13
48
2.74
2.72
1.0
1.3
—
—
—
0
0
101
736
1.42
2.68
1.9
1.4
—
—
—
0
0
72
491
1.51
2.67
4.6
3.7
2.38
1.85
mmol/l
0.90
58
399
26
134
1.97
2.62
1.4
1.1
—
—
—
0
0
36
210
1.75
2.50
1.9
1.9
2.89
5.01
iu/l
1.27
13
77
98
720
1.41
2.49
1.6
1.3
—
—
—
0
0
27
144
1.90
2.49
1.1
1.1
—
—
—
0
0
212
1752
1.28
2.45
3.1
3.1
7.85
7.89
mmol/l
0.04
189
1519
705
6688
1.33
2.44
4.2
3.8
4.67
4.77
mmol/l
1.68
675
6307
109
820
1.38
2.42
1.2
1.2
—
—
—
0
0
17
78
2.20
2.32
1.2
2.1
—
—
—
0
0
9
28
3.24
2.31
1.0
1.3
—
—
—
0
0
702
6670
1.31
2.29
4.0
3.7
1.43
1.50
mmol/l
4.23
673
6272
184
1507
1.28
2.27
3.7
3.4
1.02
1.02
kg/l
0.18
34
195
56
380
1.51
2.17
2.3
1.8
—
—
—
0
0
677
6416
1.28
2.16
3.7
3.4
1.30
1.25
mmol/l
1.02
648
6003
15
68
2.23
2.12
1.1
2.0
—
—
—
0
0
12
49
2.47
2.11
1.8
2.5
—
—
—
0
0
6
15
4.02
2.04
3.3
2.8
52.75
55.50
%
—
6
15
27
156
1.75
1.98
2.0
2.3
—
—
—
0
0
67
481
1.43
1.97
2.2
1.8
—
—
—
0
0
7
21
3.35
1.97
2.4
2.8
—
—
—
0
0
9
33
2.75
1.93
1.9
2.5
458.33
740.45
u/ml
—
9
33
29
173
1.70
1.92
2.4
2.3
4.12
4.84
umol/l
0.55
24
126
22
121
1.84
1.90
3.3
3.9
25.85
27.37
mg/l
0.12
17
96
67
485
1.41
1.90
2.2
1.8
—
—
—
0
0
7
22
3.20
1.88
1.1
1.2
—
—
—
0
0
45
302
1.52
1.86
2.9
3.0
—
—
—
0
0
67
489
1.40
1.82
2.2
1.8
—
—
—
0
0
198
1680
1.23
1.79
1.9
1.7
—
—
—
0
0
25
146
1.73
1.79
1.5
1.2
261.78
249.64
u/ml
0.08
18
87
67
491
1.40
1.78
4.3
3.9
60.96
29.87
ug/l
0.33
51
393
67
491
1.40
1.78
2.2
1.8
—
—
—
0
0
71
528
1.38
1.74
5.3
8.5
0.66
1.14
mmol/l
0.55
54
415
51
358
1.45
1.72
3.8
2.6
78.65
73.79
e9/l
0.26
38
267
68
503
1.38
1.72
3.6
4.4
0.41
0.15
%
0.44
22
140
45
308
1.49
1.72
2.1
1.7
—
—
—
0
0
51
359
1.45
1.70
1.2
1.1
—
—
—
0
0
62
453
1.40
1.69
2.2
1.9
—
—
—
0
0
40
270
1.51
1.64
2.8
4.1
24.33
23.91
mmol/l
0.54
40
265
137
1130
1.25
1.60
1.7
1.5
—
—
—
0
0
16
84
1.92
1.60
1.5
1.8
—
—
—
0
0
10
43
2.34
1.59
2.9
2.3
—
—
—
0
0
194
1665
1.21
1.57
1.7
1.6
1.29
1.38
mmol/l
0.92
179
1424
45
630
0.70
1.56
4.1
3.5
—
—
—
0
0
160
1349
1.23
1.54
1.8
1.7
—
—
—
0
0
18
100
1.82
1.54
1.6
1.3
—
—
—
0
0
25
154
1.64
1.51
1.8
1.7
—
—
—
0
0
64
480
1.36
1.51
3.3
4.2
1.06
0.69
%
0.21
17
136
69
525
1.34
1.49
3.6
4.3
1.80
1.04
%
0.42
23
163
17
94
1.83
1.48
2.1
1.7
—
—
—
0
0
61
457
1.36
1.46
3.6
3.2
—
—
—
0
0
65
492
1.35
1.46
1.4
1.4
—
—
—
0
0
33
220
1.52
1.45
3.0
2.2
—
—
—
0
0
117
961
1.25
1.43
1.6
1.6
951.83
1208.57
nmol/l
2.92
96
721
34
230
1.50
1.41
1.3
1.2
—
—
—
0
0
256
2279
1.18
1.37
1.5
1.6
—
—
—
0
0
13
68
1.93
1.34
1.0
1.1
9.62
7.71
iu/ml
—
5
17
41
293
1.42
1.31
3.5
6.6
—
—
—
0
0
8
34
2.37
1.29
2.3
2.8
—
—
—
0
0
62
476
1.33
1.29
3.2
4.5
0.07
0.10
%
0.10
14
115
18
107
1.70
1.26
1.2
1.1
11.00
112.45
iu/ml
—
5
32
91
738
1.26
1.26
5.1
5.2
1.07
1.04
mmol/l
0.65
86
686
8
36
2.23
1.24
4.9
8.5
—
—
—
0
0
24
157
1.54
1.18
1.1
1.8
—
—
—
0
0
27
185
1.47
1.09
1.3
1.5
442.04
458.77
mg/l
0.10
27
172
5
21
2.39
1.09
1.6
1.7
—
—
—
0
0
11
59
1.88
1.07
1.2
1.2
—
—
—
0
0
11
59
1.88
1.07
1.1
1.2
—
—
—
0
0
164
1436
1.18
1.07
3.4
3.3
419.62
189.21
mg/l
0.27
112
933
69
554
1.27
1.06
1.5
1.4
32.51
24.58
iu/l
1.01
61
472
31
221
1.42
1.04
10.4
8.8
—
—
—
0
0
9
46
1.97
1.03
1.2
1.1
—
—
—
0
0
7
35
2.01
1.00
1.0
1.0
—
—
—
0
0
172
1522
1.16
0.99
3.9
3.9
12.01
9.72
mg/mmol
0.19
116
966
79
951
0.81
0.98
1.3
1.3
—
—
—
0
0
5
23
2.18
0.98
1.2
2.4
2.08
1.35
ug/l
—
5
23
0
32
0.00
0.95
0.0
1.0
—
—
—
0
0
6
117
0.51
0.94
7.0
2.7
—
—
—
0
0
7
37
1.90
0.94
2.6
5.2
11.03
11.01
%
—
7
37
7
37
1.90
0.94
1.0
1.0
—
—
—
0
0
24
167
1.45
0.93
1.2
1.7
33.26
12.81
e6/l
0.27
19
130
24
167
1.45
0.93
1.2
1.8
88.84
157.43
e6/l
0.32
19
134
6
29
2.08
0.89
1.0
1.3
19328.33
38626.47
e6/l
—
6
17
8
42
1.91
0.88
4.4
2.2
—
—
—
0
0
6
30
2.01
0.87
1.0
1.5
62.05
71.47
nmol/24h
—
6
30
222
2023
1.13
0.85
2.9
2.9
—
—
—
0
0
6
31
1.94
0.84
1.0
1.3
1407.67
2223.36
e6/l
—
6
22
35
269
1.31
0.79
2.1
2.2
—
—
—
0
0
43
342
1.27
0.76
4.3
2.2
—
—
—
0
0
9
53
1.71
0.75
1.1
2.2
46.78
42.62
%
—
9
53
5
24
2.09
0.74
1.2
2.3
44.10
77.96
ug/l
—
5
24
43
344
1.26
0.73
1.4
1.5
—
—
—
0
0
20
142
1.42
0.73
2.0
1.4
—
—
—
0
0
7
39
1.80
0.72
1.1
1.2
—
—
—
0
0
10
60
1.67
0.72
1.1
1.1
—
—
—
0
0
32
247
1.31
0.71
8.6
10.9
—
—
—
0
0
5
26
1.93
0.70
1.0
1.4
—
—
—
0
0
110
969
1.16
0.70
4.6
4.2
1.90
2.12
ug/l
0.15
102
876
9
142
0.63
0.70
1.2
1.4
—
—
—
0
0
13
85
1.54
0.69
1.5
1.7
—
—
—
0
0
16
110
1.46
0.68
1.2
1.1
—
—
—
0
0
15
102
1.48
0.68
2.6
2.6
—
—
—
0
0
7
43
1.63
0.67
1.1
1.1
—
—
—
0
0
7
43
1.63
0.67
1.1
1.2
—
—
—
0
0
5
28
1.79
0.66
1.2
1.4
103.00
146.30
nmol/l
—
5
28
260
2750
0.92
0.51
2.4
2.5
—
—
—
0
0
13
92
1.42
0.50
1.4
1.3
—
—
—
0
0
40
336
1.20
0.48
1.4
1.4
—
—
—
0
0
7
49
1.43
0.46
1.0
1.4
73.00
68.76
umol/l
—
7
49
16
121
1.33
0.44
1.3
1.1
—
—
—
0
0
14
185
0.75
0.43
1.3
1.2
—
—
—
0
0
5
32
1.57
0.42
2.6
3.2
—
—
—
0
0
5
32
1.57
0.42
1.0
1.4
—
—
—
0
0
22
176
1.26
0.42
1.4
1.1
—
—
—
0
0
13
96
1.36
0.41
4.8
4.3
—
—
—
0
0
8
58
1.38
0.41
1.5
3.1
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
6.0
—
25.30
—
0
15
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
9.5
—
—
—
0
0
5
34
1.47
0.40
1.2
1.6
—
—
—
0
0
39
334
1.18
0.40
1.4
1.4
—
—
—
0
0
11
80
1.38
0.38
1.4
1.4
—
—
—
0
0
65
582
1.13
0.38
2.1
2.2
13815.81
4507.66
u/l
0.85
26
245
50
566
0.88
0.37
1.9
1.7
—
—
—
0
0
8
115
0.69
0.37
3.9
2.9
4.81
4.94
kpa
—
8
115
8
115
0.69
0.37
3.9
2.9
9.81
9.03
kpa
—
8
115
26
307
0.84
0.33
1.4
1.4
10.09
10.29
u/l
0.03
21
245
6
87
0.69
0.33
2.5
2.2
—
—
—
0
0
21
173
1.22
0.33
1.2
1.2
—
—
—
0
0
41
465
0.88
0.32
2.4
3.3
1.24
1.23
mmol/l
0.51
32
393
61
551
1.12
0.32
2.6
3.5
—
—
—
0
0
10
75
1.34
0.30
1.5
1.3
36.43
34.25
nmol/l
—
10
66
21
176
1.20
0.29
1.4
1.1
—
—
—
0
0
7
57
1.23
0.29
1.6
2.1
—
—
—
0
0
43
384
1.13
0.28
2.3
2.2
10.77
12.33
nmol/l
0.55
38
356
9
116
0.77
0.27
1.6
1.4
—
—
—
0
0
22
187
1.18
0.27
6.3
4.5
—
—
—
0
0
62
570
1.09
0.25
2.4
2.7
0.75
0.72
ug/l
0.05
34
339
25
217
1.16
0.24
2.6
3.8
0.14
0.26
g/l
—
10
88
9
77
1.17
0.24
1.3
1.2
25.78
41.70
mg/l
—
9
55
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
—
—
0
0
0
12
0.00
0.21
0.0
7.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
4702.13
—
0
8
96
910
1.06
0.19
1.8
1.9
—
—
—
0
0
7
58
1.21
0.18
7.6
3.2
—
—
—
0
0
7
63
1.11
0.17
1.3
1.2
—
—
—
0
0
12
101
1.19
0.16
2.5
3.8
—
—
—
0
0
8
71
1.13
0.16
1.3
1.1
223.13
223.00
mg/l
—
8
58
8
72
1.11
0.16
1.8
2.1
—
—
—
0
0
164
1592
1.04
0.14
3.5
3.2
—
—
—
0
0
47
441
1.07
0.14
1.4
1.5
256.34
310.57
mu/l
1.49
41
399
23
253
0.91
0.13
5.1
4.4
—
—
—
0
0
128
1240
1.04
0.13
1.4
1.6
74775211.92
24342535.44
pmol/l
0.29
111
1064
61
582
1.05
0.11
1.3
1.4
—
—
—
0
0
5
45
1.11
0.10
1.6
2.9
—
—
—
0
0
5
47
1.06
0.09
1.0
1.2
—
—
—
0
0
31
329
0.94
0.09
1.5
1.3
—
—
—
0
0
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
6
55
1.09
0.09
1.3
1.2
—
—
—
0
0
6
56
1.07
0.08
1.2
1.1
—
0.25
—
0
9
5
62
0.81
0.08
1.0
1.4
1.86
1.24
promille
—
5
48
7
64
1.09
0.08
2.1
1.6
—
—
—
0
0
7
67
1.05
0.08
4.4
2.3
3.96
3.96
mmol/l
—
7
67
7
67
1.05
0.08
4.4
2.3
106.57
106.31
mmol/l
—
7
67
7
67
1.05
0.08
4.4
2.3
—
—
—
0
0
12
133
0.90
0.07
2.6
3.6
4.12
4.15
e9/l
0.03
12
133
13
143
0.91
0.07
3.6
4.0
—
—
—
0
0
12
108
1.11
0.07
3.8
2.9
—
—
—
0
0
12
132
0.91
0.06
3.3
3.7
16.34
27.76
mg/l
—
5
83
188
1853
1.02
0.06
3.7
3.5
0.00
0.01
estimate
1.34
61
696
11
120
0.92
0.05
1.5
1.2
—
—
—
0
0
12
111
1.08
0.04
1.3
1.7
8.65
7.71
mmol/l
0.66
12
106
13
138
0.94
0.02
2.5
3.8
57.46
56.66
%
0.09
13
138
13
124
1.05
0.00
1.6
2.1
136.43
132.49
g/l
—
7
93
14
137
1.02
0.00
4.8
4.7
9.03
8.44
kpa
0.57
14
137
18
181
0.99
0.00
6.0
4.8
1.25
1.36
mg/l
0.46
18
170
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
314.00
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
5
50
1.00
0.00
1.6
1.3
2.20
1.35
nmol/l
—
5
44
0
5
0.00
0.00
0.0
2.6
—
194.60
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
11.63
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
15.62
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
33.93
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_URTICA_IDIOPAT and mortality.

Females

Parameter HR [95% CI] p-value
L12_URTICA_IDIOPAT 1.082 [0.86, 1.37] 0.511
Birth year 0.995 [0.99, 1.0] 0.272

During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 2558 females with L12_URTICA_IDIOPAT died.

Males

Parameter HR [95% CI] p-value
L12_URTICA_IDIOPAT 1.073 [0.8, 1.43] 0.632
Birth year 0.991 [0.98, 1.0] 0.045

During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 1446 males with L12_URTICA_IDIOPAT died.

Mortality risk

Mortality risk for people of age

years, who have L12_URTICA_IDIOPAT.

N-year risk Females Males
1 0.094% 0.229%
5 0.676% 1.245%
10 1.577% 3.287%
15 3.005% 6.357%
20 5.357% 10.726%

Relationships between endpoints

Index endpoint: L12_URTICA_IDIOPAT – Idiopathic urticaria

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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